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NIH funding notice PAS-25-205

Stimulating Hematology Investigation: New Endeavors (SHINE) (R01 Clinical Trial Not Allowed)

Open. Closes January 6, 2028.

Posted
November 6, 2024
Close date
January 6, 2028
Activity codes
R01
Institutes taking part
NIDDK, NHLBI, NIA

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PAS-22-096 Stimulating Hematology Investigation: New Endeavors (SHINE) (R01 Clinical Trial Not Allowed)
  2. 2 steps back: PAS-19-105 Stimulating Hematology Investigation: New Endeavors (SHINE) (R01 Clinical Trial Not Allowed)
  3. 3 steps back: PAS-16-033 Stimulating Hematology Investigation: New Endeavors (SHINE) (R01)
  4. 4 steps back: PAS-13-031 Stimulating Hematology Investigation: New Endeavors (SHINE) (R01)
  5. 5 steps back: PAS-10-046 Stimulating Hematology Investigation: New Endeavors (SHINE) (R01)

Who won it before

197 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $83,012,846 in first-year total cost, median $425,543.

Most frequent study sections

  1. Molecular and Cellular Hematology Study Section[MCH]70
  2. Hemostasis, Thrombosis, Blood Cells and Transfusion Study Section[HTBT]38
  3. Basic Biology of Blood, Heart and Vasculature Study Section [BBHV]30
  4. Special Emphasis Panel[ZRG1 VH-C (02)]8
  5. Special Emphasis Panel[ZRG1 VH-D (02)]5

Most frequent institutions

  1. CINCINNATI CHILDRENS HOSP MED CTR14
  2. UNIVERSITY OF WISCONSIN-MADISON9
  3. ALBERT EINSTEIN COLLEGE OF MEDICINE7
  4. BOSTON CHILDREN'S HOSPITAL7
  5. STANFORD UNIVERSITY7
Competing awards under PAS-25-205 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025Base editing and prime editing for sickle cell disease2R01HL156647-05 · under PAS-22-096CZECHOWICZ, AGNIESZKALIU, DAVID RWEISS, MITCHELL JST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN$830,254TAG
2025Erythroblastic island macrophages in normal erythropoiesis and disordered erythropoiesis in polycythemia vera1R01HL181370-01 · under PAS-22-096AN, XIULINEW YORK BLOOD CENTER, NY$801,628HTBT
2025Stress Granules in Red Blood Cell Development1R01DK143991-01 · under PAS-22-096ZON, LEONARD IRABOSTON CHILDREN'S HOSPITAL, MA$801,000BBHV
2025Probing human HSC genesis in a flow-directed 3D hemogenic vascular niche model1R01HL179317-01 · under PAS-22-096HADLAND, BRANDON KZHENG, YINGFRED HUTCHINSON CANCER CENTER, WA$776,511ZRG1
2025The molecular pathophysiology of the congenital dyserythropoietic anemias2R01HL148333-06A1 · under PAS-22-096KHORIATY, RAMIUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$775,521HTBT
2025Niche-specific endothelial mechanisms regulating the extravasation of hematopoietic stem cells1R01HL178832-01 · under PAS-22-096HAGEDORN, ELLIOTT JENNINGSBOSTON MEDICAL CENTER, MA$734,607ZRG1
2025Mechanisms of granulocyte homeostasis2R01HL122661-09 · under PAS-22-096GRIMES, H. LEIGHTONSALOMONIS, NATHAN G.CINCINNATI CHILDRENS HOSP MED CTR, OH$728,731ZRG1
2025Role of environmental exposure and inflammation on hematopoietic stem cell disorders1R01DK144815-01 · under PAS-22-096VERMA, DIVIJALBERT EINSTEIN COLLEGE OF MEDICINE, NY$560,100HTBT
2025Hematopoietic Regulation via GATA Switches2R01DK068634-20 · under PAS-22-096BRESNICK, EMERY H.UNIVERSITY OF WISCONSIN-MADISON, WI$545,540ZRG1
2025Protein Aggregation in Hematopoietic Stem Cells1R01HL180754-01 · under PAS-22-096SIGNER, ROBERT A.J.UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$536,468HTBT
2025The role of SRCAP in therapy related clonal hematopoiesis1R01DK141535-01 · under PAS-22-096SPERLING, ADAMBRIGHAM AND WOMEN'S HOSPITAL, MA$465,155BBHV
2025Regenerative function of myeloid derived suppressor cells in the damaged bone marrow endothelial niche1R01HL176781-01A1 · under PAS-22-096PAJCINI, KOSTANDINUNIVERSITY OF ILLINOIS AT CHICAGO, IL$461,132HTBT
2025Structural Proteome Diversity as a Determinant of Hematopoietic Aging1R56DK141457-01A1 · under PAS-22-096CATIC, ANDREDI STEFANO, BRUNOBAYLOR COLLEGE OF MEDICINE, TX$200,000BBHV
2025CLINICAL SIGNIFICANCE OF SOMATIC MOSAIC STATES IN THE CONTEXT OF SHORT TELOMERES1R56DK141633-01 · under PAS-22-096FERRER, ALEJANDROMAYO CLINIC ROCHESTER, MN$150,000BBHV
2025Correcting the myeloid bias of aged HSPCs by preventing linker histone turnover1R56DK143320-01 · under PAS-22-096GUO, SHANGQINYALE UNIVERSITY, CT$133,333HTBT
2025Dissecting the Roles of PPM1D and TP53 in Hematopoietic Stem Cells and Clonal Hematopoiesis1R56DK142828-01 · under PAS-22-096MILLER, PETER GRANTMASSACHUSETTS GENERAL HOSPITAL, MA$133,328BBHV
2025Inflammatory landscapes shaped by bone marrow cavities define hematopoietic response to stress and clonal selection1R56DK143951-01 · under PAS-22-096YEH, SHU-CHIUNIVERSITY OF ROCHESTER, NY$133,315BBHV
2025Early myeloid lineage specification mechanisms at the top of the hematopoietic hierarchy1R56DK139218-01A1 · under PAS-22-096KANG, YOON AWASHINGTON UNIVERSITY, MO$86,856BBHV
2024Intracellular trafficking of the essential signaling metabolite heme in myeloid cells: impact on physiology and disease1R01DK138430-01A1 · under PAS-22-096NAGY, LASZLOSAEZ, ENRIQUESCRIPPS RESEARCH INSTITUTE, THE, CA$780,012III
2024Critical roles of RNA m5C-MBD6-H2AK119ub deubiquitylation axis in TET2-mediated HSC regulation1R01HL174477-01 · under PAS-22-096HE, CHUANXU, MINGJIANGUNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX$717,415HTBT
2024Investigating and targeting the translational landscape of DBA1R01DK136961-01A1 · under PAS-22-096BARNA, MARIASAKAMOTO, KATHLEEN MSTANFORD UNIVERSITY, CA$678,778TAG
2024Molecular mechanism underlying clonal expansion of hematopoietic stem cells2R01HL150624-05 · under PAS-22-096LIU, YANNORTHWESTERN UNIVERSITY AT CHICAGO, IL$678,278BBHV
2024Erythroid Self-Renewal1R01HL172500-01 · under PAS-22-096PALIS, JAMESSTEINER, LAURIE A.UNIVERSITY OF ROCHESTER, NY$677,600BBHV
2024RUNX1-mediated regulation of MEP fate specification1R01DK139675-01 · under PAS-22-096KRAUSE, DIANE SYALE UNIVERSITY, CT$669,741BBHV
2024Regulatory mechanisms of hematopoietic stem cell functions post-transplant1R01HL167731-01A1 · under PAS-22-096FILIPPI, MARIE-DOMINIQUECINCINNATI CHILDRENS HOSP MED CTR, OH$642,754HTBT
2024Altered RNA fates due to an MDS driver mutation in SF3B11R01HL167071-01A1 · under PAS-22-096NEUGEBAUER, KARLA MPILLAI, MANOJ M.YALE UNIVERSITY, CT$619,750HTBT
2024Developing Effective Approaches to Extend Hematopoietic Healthspan by Targeting Cell-Extrinsic and Cell-Intrinsic Alterations at Middle Age2R01DK118072-06A1 · under PAS-22-096TROWBRIDGE, JENNIFER JEANJACKSON LABORATORY, ME$615,355CMAD
2024Molecular and Cellular Mechanisms of Mutant ASXL1-driven Clonal Hematopoiesis1R01AG081469-01A1 · under PAS-22-096ZHANG, JINGUNIVERSITY OF WISCONSIN-MADISON, WI$570,922CMAD
2024Regulation of hematopoietic stem cell niche aging by the sympathetic nervous system1R01HL174801-01 · under PAS-22-096MARIANOVICH, MARIAALBERT EINSTEIN COLLEGE OF MEDICINE, NY$566,022HTBT
2024Skeletal heterogeneity of bone marrow stress responses.1R01DK141465-01 · under PAS-22-096LUCAS, DANIELCINCINNATI CHILDRENS HOSP MED CTR, OH$518,603HTBT
2024Modulation of Endoplasmic Reticulum Associated Degradation to Support Ex Vivo Expansion of Hematopoietic Stem Cells1R01HL174566-01 · under PAS-22-096LI, QINGUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$503,097BBHV
2024Reprogramming of hematopoietic stem cells during contact with the perivascular niche1R01HL174965-01 · under PAS-22-096TAMPLIN, OWEN JAMESUNIVERSITY OF WISCONSIN-MADISON, WI$493,810HTBT
2024The role of the N-terminus of GATA1 in erythropoiesis1R01DK141059-01 · under PAS-22-096CRISPINO, JOHN DST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN$475,020HTBT
2024Elucidating the Role of Integrator Complex in Erythropoiesis1R01HL173979-01 · under PAS-22-096STEINER, LAURIE A.WAGNER, ERIC JUNIVERSITY OF ROCHESTER, NY$385,000BBHV
2024Elucidation of the mechanisms by which fatty acids drive megakaryopoiesis1R01DK139341-01 · under PAS-22-096MACHLUS, KELLIE RAEBOSTON CHILDREN'S HOSPITAL, MA$354,000HTBT
2024α-Synuclein Regulation of the Erythroid Iron Restriction Response1R56DK141123-01 · under PAS-22-096GOLDFARB, ADAM N.UNIVERSITY OF VIRGINIA, VA$225,000HTBT
2024Mitochondria mediated intercellular metabolic coupling in bone marrow regeneration2R01DK124115-04A1 · under PAS-22-096CANCELAS, JOSE A.DANA-FARBER CANCER INST, MA$150,000ZRG1
2023Mechanisms of Intercellular Heme Homeostasis in Liver1R01DK134783-01 · under PAS-22-096YASUDA, MAKIKOICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$655,405HTBT
2023Preserving bone marrow niche integrity and function to rejuvenate aged hematopoietic stem cells1R01HL166512-01A1 · under PAS-22-096BUTLER, JASON MATHEWUNIVERSITY OF FLORIDA, FL$651,013HTBT
2023Gradient biomaterials to investigate niche regulation of hematopoiesis2R01DK099528-06A1 · under PAS-22-096HARLEY, BRENDAN A.UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$601,729ZRG1
2023Regulation of erythroid iron metabolism by the CLPX unfoldase1R01DK137107-01 · under PAS-22-096YIEN, YVETTE YUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$542,538HTBT
2023Using spatial, single-cell genomic recording to investigate age-associated clonal hematopoiesis1R01AG080982-01 · under PAS-22-096ELOWITZ, MICHAEL BLOIS, CARLOSLU, RONGUNIVERSITY OF SOUTHERN CALIFORNIA, CA$541,387ZRG1
2023Improving the interaction of hematopoietic stem cells with the perivascular niche to promote engraftment2R56HL142998-06 · under PAS-22-096TAMPLIN, OWEN JAMESUNIVERSITY OF WISCONSIN-MADISON, WI$537,640DEV2
2023Mitochondria in the Regulation of Terminal Erythropoiesis2R01HL136255-05A1 · under PAS-22-096GHAFFARI, SAGHIICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$533,421BBHV
2023Deciphering a Novel Mechanism for Iron-sensing at Mitochondria and Its Role in Erythropoiesis1R01DK134341-01 · under PAS-22-096SEKINE, SHIORISEKINE, YUSUKEUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$529,999CSRS
2023EpoR & Stat5 regulation of ribosome biogenesis and protein synthesis in erythropoiesis1R01DK136321-01 · under PAS-22-096SOCOLOVSKY, MERAVUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$515,212ZRG1
2023Molecular Mechanisms of MDS pathogenesis with aging1R01AG080142-01A1 · under PAS-22-096KOUSTENI, STAVROULACOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$500,000BCO
2023The Roles of Lipid Metabolism in the Maintenance of Hematopoietic Stem Cells2R01DK098263-12A1 · under PAS-22-096ITO, KEISUKEALBERT EINSTEIN COLLEGE OF MEDICINE, NY$489,880BBHV
2023Establishing CUX1 as a determinant of hematopoietic stem cell fate1R01HL166184-01 · under PAS-22-096MCNERNEY, MEGANUNIVERSITY OF CHICAGO, IL$474,898HTBT
2023Aberrant glycolysis as a driver of mutant HSPC expansion in clonal hematopoiesis1R01DK137183-01 · under PAS-22-096PIETRAS, ERIC MUNIVERSITY OF COLORADO DENVER, CO$456,912HTBT
2023Diabetic Memory in Hematopoietic Stem Cells1R01DK133145-01A1 · under PAS-22-096REYNAUD, DAMIENCINCINNATI CHILDRENS HOSP MED CTR, OH$450,413BBHV
2023Mutual reinforcement between somatic mutations and transcription factors in clonal hematopoiesis1R01DK132286-01A1 · under PAS-22-096CHENG, XIAODONGHUANG, YUNTEXAS A&M UNIVERSITY HEALTH SCIENCE CTR, TX$445,109BBHV
2023Dormancy-dependent determination of hematopoietic stem cell fate from hemogenic endothelium1R01HL168110-01 · under PAS-22-096HADLAND, BRANDON KFRED HUTCHINSON CANCER CENTER, WA$440,000BBHV
2023The role of Septin6 Group in Murine and Human Hematopoiesis1R01DK137172-01 · under PAS-22-096WILLIAMS, DAVID ABOSTON CHILDREN'S HOSPITAL, MA$354,000BBHV
2023Heme-induced metabolic stress drives ferroptosis in sickle cell disease1R01DK139694-01A1 · under PAS-22-096ZHU, XINGGUOAUGUSTA UNIVERSITY, GA$308,000HTBT
2023Defining the role of Wnt11 and Wnt5a in regulating hematopoietic and skeletal stem cell self-renewal potential during homeostasis and stress1R01DK135090-01A1 · under PAS-22-096KLUG, CHRISTOPHERWEINMANN, AMY SUSANUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$297,000HTBT
2023Genetic Dissection of Stress Responses in Shwachman-Diamond Syndrome1R01DK132812-01A1 · under PAS-22-096COREY, SETH JOELCLEVELAND CLINIC LERNER COM-CWRU, OH$241,500HTBT
2023Protein homeostasis in hematopoietic stem cells2R01DK116951-06 · under PAS-22-096SIGNER, ROBERT A.J.UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$237,000BBHV
2023Investigating and targeting the translational landscape of DBA1R56DK136961-01 · under PAS-22-096BARNA, MARIASAKAMOTO, KATHLEEN MSTANFORD UNIVERSITY, CA$150,000TAG
2023Flow, Fatty Acid Biosynthesis, and Hematopoiesis1R56DK137153-01 · under PAS-22-096FANG, LONGHOUWENZEL, PAMELA LYNNYOSHIMOTO, MOMOKOMETHODIST HOSPITAL RESEARCH INSTITUTE, TX$150,000BBHV
2023Delineating Drivers of Inflammation and Progression in Clonal Hematopoiesis1R56DK138826-01A1 · under PAS-22-096FERRELL, PAUL BVANDERBILT UNIVERSITY MEDICAL CENTER, TN$150,000BBHV
2023Developing Effective Approaches to Extend Hematopoietic Healthspan by Targeting Cell-Extrinsic and Cell-Intrinsic Alterations at Middle Age2R56DK118072-06 · under PAS-22-096TROWBRIDGE, JENNIFER JEANJACKSON LABORATORY, ME$100,000CMAD
2023Deciphering the molecular mechanism of ineffective erythropoiesis in MDS-5q1R56DK136280-01 · under PAS-22-096ABKOWITZ, JANIS LUNIVERSITY OF WASHINGTON, WA$99,999HTBT
2022Privileged and primitive hematopoietic stem cells, niches, and regulatory T cells2R01HL129506-07 · under PAS-19-105FUJISAKI, JOJIBETH ISRAEL DEACONESS MEDICAL CENTER, MA$774,122TTT
2022Eltombopag: Novel Mode of Action on Normal and Aplastic Anemia Hematopoietic Stem Cells1R01DK131923-01A1 · under PAS-19-105JHA, BABAL KMACIEJEWSKI, JAROSLAW P.CLEVELAND CLINIC LERNER COM-CWRU, OH$658,812HTBT
2022ULK-mediated autophagy of α-globin in ß-thalassemia1R01HL165798-01 · under PAS-19-105WEISS, MITCHELL JST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN$652,585HTBT
2022Mechanisms that regulate erythroid differentiation of hematopoietic stem cells1R01HL165145-01 · under PAS-19-105NAKADA, DAISUKEBAYLOR COLLEGE OF MEDICINE, TX$612,835HTBT
2022Oxidative stress mechanisms regulating gamma-globin gene transcription in sickle cell disease1R01HL160697-01 · under PAS-19-105ZENNADI, RAHIMADUKE UNIVERSITY, NC$610,202HTBT
2022Mechanisms of marrow microenvironmental aging and their impact of progression of clonal hematopoiesis1R01AG079556-01 · under PAS-19-105BECKER, MICHAEL WCALVI, LAURA MUNIVERSITY OF ROCHESTER, NY$534,854HTBT
2022Hematopoietic Stem Cell engraftment in the injured niche1R01HL162649-01 · under PAS-19-105LUCAS, DANIELCINCINNATI CHILDRENS HOSP MED CTR, OH$526,265HTBT
2022PI3 Kinase Inactivation in Myelodysplastic Syndrome1R01DK130895-01A1 · under PAS-19-105GRITSMAN, KIRAALBERT EINSTEIN COLLEGE OF MEDICINE, NY$518,587HTBT
2022Metabolic regulation of stem cell niche development and function1R01HL162725-01 · under PAS-19-105QU, CHENG-KUIEMORY UNIVERSITY, GA$508,625BBHV
2022Hematopoietic stem and progenitor cell regulation of the niche through extracellular vesicles1R01HL164633-01 · under PAS-19-105KURRE, PETERCHILDREN'S HOSP OF PHILADELPHIA, PA$440,000HTBT
2022The role of glycolysis and glucose oxidation in hematopoiesis1R01HL161387-01 · under PAS-19-105AGATHOCLEOUS, MICHALISUT SOUTHWESTERN MEDICAL CENTER, TX$403,615BBHV
2022Control of hematopoietic maturation by Lin28b/let-71R01DK134515-01 · under PAS-22-096ROWE, ROBERT GRANTBOSTON CHILDREN'S HOSPITAL, MA$354,000HTBT
2022Understanding the role of cell-cycle specific RNAs in hematopoiesis1R01DK136116-01A1 · under PAS-19-105DI RUSCIO, ANNALISABETH ISRAEL DEACONESS MEDICAL CENTER, MA$345,800BBHV
20223D Genome Reorganization and Epigenome Dynamics of Clonal Hematopoiesis1R56AG071766-01A1 · under PAS-19-105LI, SHENGOGURO, HIDEYUKITROWBRIDGE, JENNIFER JEANJACKSON LABORATORY, ME$343,103BBHV
2022Role of IL-10R signaling in inflammation induced exhaustion of HSC and emergence of JAK2V617F clonal hematopoiesis1R01DK136069-01 · under PAS-19-105FLEISCHMAN, ANGELA GOFFREDOUNIVERSITY OF CALIFORNIA-IRVINE, CA$224,896BBHV
2022Targeting splicing in myelodysplasia through GSK-31R56DK133258-01 · under PAS-19-105KLEIN, PETER SUNIVERSITY OF PENNSYLVANIA, PA$99,999HTBT
2022Mechanistic understanding of dysregulated iron metabolism in polycythemia vera1R56DK132146-01 · under PAS-19-105GINZBURG, YELENAHOFFMAN, RONALDICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$99,997HTBT
2022Clarifying the Origins of Blood Stem Cell Heterogeneity by Single-Cell Epigenetic State Profiling1R56DK132084-01A1 · under PAS-22-096KUEH, HAO YUANVAUGHAN, JOSHUAUNIVERSITY OF WASHINGTON, WA$99,374BBHV
2021REGULATION OF HEMATOPOIETIC PROGENITORS BY DE NOVO DNA METHYLATION2R01DK092883-10 · under PAS-19-105GOODELL, MARGARET A.BAYLOR COLLEGE OF MEDICINE, TX$664,850MCH
2021The role of mitochondria in hematopoietic stem cell self-renewal1R01HL151654-01A1 · under PAS-19-105FILIPPI, MARIE-DOMINIQUECINCINNATI CHILDRENS HOSP MED CTR, OH$615,104MCH
2021Erythrocyte maturation through global remodeling of the proteome1R01HL153970-01A1 · under PAS-19-105FINLEY, DANIEL JFLEMING, MARK DHARVARD MEDICAL SCHOOL, MA$598,449MBPP
2021Role of the local vascular microenvironment in the bone marrow response to inflammation1R01HL158616-01 · under PAS-19-105LUCAS, DANIELCINCINNATI CHILDRENS HOSP MED CTR, OH$568,892BBHV
2021The Role of PHF6 in HSC self-renewal and myeloid expansion1R01HL155144-01 · under PAS-19-105PARALKAR, VIKRAM R.UNIVERSITY OF PENNSYLVANIA, PA$536,436MCH
2021Hematopoiesis in germline RUNX1mutation carriers: impact of inflammation and the bone marrow niche1R01HL155426-01A1 · under PAS-19-105AGARWAL, ANUPRIYAGODLEY, LUCY ANNOREGON HEALTH & SCIENCE UNIVERSITY, OR$532,884HTBT
2021Exosome educated monocytes for acute radiation syndrome1R01HL153721-01A1 · under PAS-19-105CAPITINI, CHRISTIANHEMATTI, PEIMANUNIVERSITY OF WISCONSIN-MADISON, WI$525,256RTB
2021The role of PHF6 in the control of hematopoietic stem cell aging.1R01AG077020-01 · under PAS-19-105FERRANDO, ADOLFO A.RABADAN, RAULCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$500,000BBHV
2021Heme synthesis, use and trafficking during erythropoiesis2R01HL031823-31 · under PAS-19-105ABKOWITZ, JANIS LUNIVERSITY OF WASHINGTON, WA$499,586MCH
2021Regulation and manipulation of the telomerase RNA component in hematopoiesis2R01DK107716-06A1 · under PAS-19-105AGARWAL, SUNEETBOSTON CHILDREN'S HOSPITAL, MA$480,051BBHV
2021Transcriptional Control of Hemoglobin Synthesis and Erythrocyte Development2R01DK050107-25 · under PAS-19-105BRESNICK, EMERY HUNIVERSITY OF WISCONSIN-MADISON, WI$478,444ZRG1
2021Molecular Analysis of Transcriptional Enhancers in Hematopoiesis2R01DK111430-06 · under PAS-19-105XU, JIANUT SOUTHWESTERN MEDICAL CENTER, TX$436,481HTBT
2021Hematopoietic Regulation via GATA Switches2R01DK068634-16 · under PAS-19-105BRESNICK, EMERY HUNIVERSITY OF WISCONSIN-MADISON, WI$432,719ZRG1
2021GATA Factor Mechanisms in Erythroid Regeneration1R01HL155439-01 · under PAS-19-105HEWITT, KYLE JUNIVERSITY OF NEBRASKA MEDICAL CENTER, NE$382,500MCH
2021The role of ascorbate in myelopoiesis and infection1R01DK125713-01A1 · under PAS-19-105AGATHOCLEOUS, MICHALISUT SOUTHWESTERN MEDICAL CENTER, TX$360,342ZRG1
2021PI3 Kinase Inactivation in Myelodysplastic Syndrome1R56DK130895-01 · under PAS-19-105GRITSMAN, KIRAALBERT EINSTEIN COLLEGE OF MEDICINE, NY$99,999HTBT
2021Gradient biomaterials to investigate niche regulation of hematopoiesis2R56DK099528-06 · under PAS-19-105HARLEY, BRENDAN A.UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$99,847ZRG1
2020Transcriptional Control During Erythropoiesis2R01DK098449-06 · under PAS-19-105BRAND, MARJORIE CAROLEPRICE, NATHAN DRANISH, JEFFREY AINSTITUTE FOR SYSTEMS BIOLOGY, WA$726,583MCH
2020miR-223 regulates endothelial to hematopoietic transition1R01DK118728-01A1 · under PAS-19-105HIRSCHI, KAREN KEMPERNICOLI, STEFANIAYALE UNIVERSITY, CT$692,264MCH
2020The Role of Erythroblastic Islands in Anemia of Inflammation1R01HL152099-01 · under PAS-19-105BLANC, LIONELKALFA, THEODOSIA ANASTASIOSCINCINNATI CHILDRENS HOSP MED CTR, OH$634,684ZRG1
2020Uncovering the role for MSI2 network in hematopoietic stem cells2R01DK101989-06A1 · under PAS-19-105KHARAS, MICHAELSLOAN-KETTERING INST CAN RESEARCH, NY$632,731MCH
2020Regulation of Ribosome Biogenesis in Hematopoietic Stem Cells1R01DK127738-01 · under PAS-19-105TONG, WEICHILDREN'S HOSP OF PHILADELPHIA, PA$602,358ZRG1
2020Mechanisms of granulocyte homeostasis2R01HL122661-05 · under PAS-19-105GRIMES, H. LEIGHTONCINCINNATI CHILDRENS HOSP MED CTR, OH$592,095MCH
2020Regulation of functionally discrete hematopietic stem cells1R01DK121062-01A1 · under PAS-19-105FILIPPI, MARIE-DOMINIQUEGRIMES, H. LEIGHTONCINCINNATI CHILDRENS HOSP MED CTR, OH$592,073ZRG1
2020The function and underlying mechanism of TET1 in myelodysplastic syndromes1R01DK124116-01 · under PAS-19-105CHEN, JIANJUNBECKMAN RESEARCH INSTITUTE/CITY OF HOPE, CA$564,921ZRG1
2020Developmental Activation of the Inflammasome Controls Hematopoietic Stem Cell Production1R01HL154580-01 · under PAS-19-105NORTH, TRISTA E.BOSTON CHILDREN'S HOSPITAL, MA$559,320MCH
2020The roles of mDia2 in hematopoietic stem and progenitor cell engraftment and migration1R01HL148012-01A1 · under PAS-19-105JI, PENGNORTHWESTERN UNIVERSITY AT CHICAGO, IL$531,208ZRG1
2020Ex vivo hematopoietic stem cell growth mediated by the heat shock response1R01DK124775-01 · under PAS-19-105SIGNER, ROBERT A.J.UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$507,548MCH
2020Heme trafficking and recycling in iron metabolism1R01DK125740-01 · under PAS-19-105HAMZA, IQBALUNIV OF MARYLAND, COLLEGE PARK, MD$493,652INMP
2020Discovery of Aging-Associated Mechanisms Causing Expansion and Progression of Clonal Hematopoiesis of Indeterminant Potential (CHIP)1R01AG069010-01A1 · under PAS-19-105TROWBRIDGE, JENNIFER JEANJACKSON LABORATORY, ME$492,639MCH
2020The role of ER associated degradation (ERAD) in hematopoietic stem cells1R01HL150707-01A1 · under PAS-19-105LI, QINGUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$490,716MCH
2020Coordinate regulation of erythroid and macrophage lineages in development by EKLF/KLF11R01DK121671-01A1 · under PAS-19-105BIEKER, JAMES JICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$465,752ZRG1
2020Identification of unique nitric oxide-expressing hematopoietic stem cells and their special vascular niche1R01DK121889-01A1 · under PAS-19-105FUJISAKI, JOJICOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$425,543MCH
2020Novel Mechanisms of Congenital Dyserythropoietic Anemia1R01DK111539-01A1 · under PAS-19-105GALLAGHER, PATRICK GHENDRICKSON, JEANNE EYALE UNIVERSITY, CT$418,383MCH
2020Crosstalk of Splicing and Signaling in HSPC fate choices1R01DK121738-01A1 · under PAS-19-105BOWMAN, TERESA VALBERT EINSTEIN COLLEGE OF MEDICINE, NY$415,030MCH
2020Iron-sensitive RNA regulation during erythropoiesis1R01DK124773-01 · under PAS-19-105ALEMAN, MARIA M.UNIV OF NORTH CAROLINA CHAPEL HILL, NC$414,753MCH
2020The roles of mDia2 in membrane remodeling and organelle clearance during reticulocyte formation1R01DK124220-01 · under PAS-19-105JI, PENGNORTHWESTERN UNIVERSITY AT CHICAGO, IL$394,349MCH
2020Estrogen Receptor Signaling in Hematopoietic Stem Cell Proliferation and Mobilization1R01DK125747-01 · under PAS-19-105OGURO, HIDEYUKIUNIVERSITY OF CONNECTICUT SCH OF MED/DNT, CT$360,800MCH
2020Inflammatory Stress Promotes Clonal Expansion of DNMT3A-mutant HSCs1R01DK124883-01A1 · under PAS-19-105CHALLEN, GRANT ANTHONYWASHINGTON UNIVERSITY, MO$238,230ZRG1
2019The molecular pathophysiology of the congenital dyserythropoietic anemias1R01HL148333-01 · under PAS-16-033KHORIATY, RAMIUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$614,718MCH
2019Regulation of Erythroid Cell Progenitors by the Nuclear Receptor Transcription Factor VDR2R01DK102945-05A1 · under PAS-16-033BARON, MARGARET HICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$585,111ZRG1
2019Dissection and Manipulation of the Cellular Response to Iron Restriction2R01DK079924-09A1 · under PAS-19-105GOLDFARB, ADAM N.UNIVERSITY OF VIRGINIA, VA$477,832INMP
2019Roles and therapeutic potential of CD150high niche-associated regulatory T cells in bone marrow injury and engraftment1R01HL145154-01A1 · under PAS-16-033FUJISAKI, JOJICOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$456,642TTT
2019Macrophage regulation of the erythron1R01DK119285-01A1 · under PAS-16-033ELLIOTT, MICHAEL RUSTYPALIS, JAMESUNIVERSITY OF ROCHESTER, NY$455,457MCH
2019Molecular mechanisms underlying clonal expansion of hematopoietic stem cells1R01HL150624-01 · under PAS-16-033LIU, YANINDIANA UNIVERSITY INDIANAPOLIS, IN$393,750MCH
2019The Metabolic Regulation of Hematopoietic Stem Cell Function1R01DK118745-01A1 · under PAS-16-033MORRISON, SEAN JUT SOUTHWESTERN MEDICAL CENTER, TX$364,500DEV2
2019The role of DNMT3A mutations in clonal heterogeneity and evolution of hematopoiesis1R01DK121831-01 · under PAS-16-033GURYANOVA, OLGA AUNIVERSITY OF FLORIDA, FL$343,125MCH
2019Osteomacs and megakaryocytes interact to regulate hematopoietic stem cell function1R01DK118782-01A1 · under PAS-16-033KACENA, MELISSA ASROUR, EDWARD FINDIANA UNIVERSITY INDIANAPOLIS, IN$317,000MCH
2019Selenium, Selenoproteins, and Stress Erythropoiesis1R01DK119865-01A1 · under PAS-16-033PAULSON, ROBERT FRANKPRABHU, KUMBLE SANDEEPPENNSYLVANIA STATE UNIVERSITY, THE, PA$316,100MCH
2019Extramedullary Hematopoiesis and the Splenic Niche1R01DK121117-01 · under PAS-16-033SCOTT, EDWARD WUNIVERSITY OF FLORIDA, FL$274,500MCH
2018Maintenance and expansion of long-term hematopoietic stem cells1R01HL141759-01 · under PAS-16-033KLEIN, PETER SUNIVERSITY OF PENNSYLVANIA, PA$540,335DEV2
2018Developing Effective Approaches to Extend Hematopoietic Healthspan by Targeting Cell-extrinsic and Cell-intrinsic Alterations at Middle Age1R01DK118072-01 · under PAS-16-033TROWBRIDGE, JENNIFER JEANJACKSON LABORATORY, ME$473,290MCH
2018Defining the Self-Renewal Program in Human Hematopoietic Stem Cells2R01DK100959-04A1 · under PAS-16-033MIKKOLA, HANNA KATRI ANNIKKIUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$432,674ZRG1
2018Hematopoietic Stem Cell Aging1R01DK117481-01 · under PAS-16-033CHEN, DANICAUNIVERSITY OF CALIFORNIA BERKELEY, CA$427,075ASG
2018Modulating HSC-niche interactions to understand aging and improve transplantation1R01HL147124-01 · under PAS-16-033NAKAUCHI, HIROMITSUSTANFORD UNIVERSITY, CA$406,711MCH
2018Improving the interaction of hematopoietic stem cells with the perivascular niche to promote engraftment1R01HL142998-01 · under PAS-16-033TAMPLIN, OWEN JAMESUNIVERSITY OF ILLINOIS AT CHICAGO, IL$399,750MCH
2018Epigenetic, Transcriptional, and Microenvironmental Determinants of Human HSC Self-Renewal1R01HL142637-01 · under PAS-16-033MAJETI, RAVINDRASTANFORD UNIVERSITY, CA$397,048MCH
2018Nutrient Sensing, Hematopoietic Stem Cell Metabolism and Aging1R01AG063404-01 · under PAS-16-033CHEN, DANICAUNIVERSITY OF CALIFORNIA BERKELEY, CA$392,500ZRG1
2018Mechanisms regulating the aging of HSC niches1R01DK112976-01A1 · under PAS-16-033FRENETTE, PAUL SALBERT EINSTEIN COLLEGE OF MEDICINE, INC, NY$375,750MCH
2018Cellular and molecular analyses of hematopoietic stem cell [HSC] interactions with bone marrow niches to improve HSC engraftment for transplantation and tolerance induction1R01DK115600-01A1 · under PAS-16-033WEISSMAN, IRVING L.STANFORD UNIVERSITY, CA$369,622TTT
2018Valine as a Metabolic Modulator of Hematopoiesis1R01DK116944-01 · under PAS-16-033NAKAUCHI, HIROMITSUSTANFORD UNIVERSITY, CA$363,414MCH
2018Defining the Niche-dependent Role of RNA Editing in Aged and MDS Hematopoietic Stem and Progenitor Cell Dysfunction2R01DK114468-02 · under PAS-16-033JAMIESON, CATRIONA HELEN MACLEODUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$353,344MCH
2018Protein Homeostasis in Hematopoietic Stem Cells1R01DK116951-01 · under PAS-16-033SIGNER, ROBERT A.J.UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$353,063MCH
2018The roles of lipid metabolism in the maintenance of hematopoietic stem cells2R01DK098263-07 · under PAS-16-033ITO, KEISUKEALBERT EINSTEIN COLLEGE OF MEDICINE, INC, NY$233,498ZRG1
2018Molecular mechanisms underlying clonal expansion of hematopoietic stem cells1R56DK119524-01 · under PAS-16-033LIU, YANINDIANA UNIVERSITY INDIANAPOLIS, IN$150,000MCH
2018Macrophage regulation of the erythron1R56DK119285-01 · under PAS-16-033ELLIOTT, MICHAEL RUSTYPALIS, JAMESUNIVERSITY OF ROCHESTER, NY$100,000MCH
2018The role, mechanism and therapeutic potential of TET1 in MDS1R56DK120282-01 · under PAS-16-033CHEN, JIANJUNBECKMAN RESEARCH INSTITUTE/CITY OF HOPE, CA$100,000MCH
2018Intrinsic and extrinsic control of erythropoietic maturation2R56DK102260-05 · under PAS-16-033BIEKER, JAMES JICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$99,999MCH
2018The metabolic regulation of hematopoietic stem cell function1R56DK118745-01 · under PAS-16-033MORRISON, SEAN JUT SOUTHWESTERN MEDICAL CENTER, TX$99,999DEV2
2018Mechanisms of Impaired Erythropoiesis in Post Burn Anemia of Critical Illness2R56DK097760-06 · under PAS-16-033MUTHUMALAIAPPAN, KUZHALILOYOLA UNIVERSITY CHICAGO, IL$99,999SAT
2018miR-223 regulates endothelial to hematopoietic transition1R56DK118728-01 · under PAS-16-033HIRSCHI, KAREN KEMPERNICOLI, STEFANIAYALE UNIVERSITY, CT$99,999MCH
2017Single cell approach to uncovering factors regulating HSC division symmetry in vivo1R01DK115577-01 · under PAS-16-033ITO, KEISUKELIN, CHARLES P.ALBERT EINSTEIN COLLEGE OF MEDICINE, INC, NY$609,456ZRG1
2017NPM1 regulation of 2'-O-methylation in hematopoiesis and bone marrow failure disorder1R01DK115536-01 · under PAS-16-033PANDOLFI, PIER PAOLOBETH ISRAEL DEACONESS MEDICAL CENTER, MA$408,289MCH
2017Novel regulation of Notch-induced HSPC expansion1R01DK110563-01A1 · under PAS-16-033BERNSTEIN, IRWIN DFRED HUTCHINSON CANCER RESEARCH CENTER, WA$396,000MCH
2017Transcript decay regulates hematopoietic aging1R01DK115454-01 · under PAS-16-033CATIC, ANDREBAYLOR COLLEGE OF MEDICINE, TX$356,625ZRG1
2017Defining the Niche-dependent Role of RNA Editing in Aged and MDS Hematopoietic Stem and Progenitor Cell Dysfunction1R01DK114468-01 · under PAS-16-033JAMIESON, CATRIONA HELEN MACLEODUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$232,500MCH
2017Defining the Self-Renewal Program in Human Hematopoietic Stem Cells2R56DK100959-04 · under PAS-16-033MIKKOLA, HANNA KATRI ANNIKKIUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$226,470MCH
2017Aging-induced Alterations in the Microenvironment as Drivers of Myeloid Lineage Skewing1R56DK112947-01A1 · under PAS-16-033TROWBRIDGE, JENNIFER JEANJACKSON LABORATORY, ME$150,000MCH
2016Regulation of Hematopoietic Progenitors by de novo DNA methylation2R01DK092883-05 · under PAS-13-031GOODELL, MARGARET A.BAYLOR COLLEGE OF MEDICINE, TX$568,203ZRG1
2016DEK Regulation of Hematopoietic Stem Cell Renewal, Fate, and Hematopoiesis1R01DK109188-01 · under PAS-13-031BROXMEYER, HAL E.MARKOVITZ, DAVID MICHAELINDIANA UNIVERSITY INDIANAPOLIS, IN$512,978MCH
2016Cdc42, hematopoietic stem cell polarity, and cell fate1R01DK104814-01A1 · under PAS-13-031ZHENG, YICINCINNATI CHILDRENS HOSP MED CTR, OH$496,716ZRG1
2016Mesenchymal Stromal Cells Regulate Hematopoietic Stem Cell Aging1R01DK107413-01 · under PAS-13-031NAKADA, DAISUKEBAYLOR COLLEGE OF MEDICINE, TX$431,329CMAD
2016Regulation of the telomerase RNA component in hematopoiesis1R01DK107716-01 · under PAS-13-031AGARWAL, SUNEETBOSTON CHILDREN'S HOSPITAL, MA$398,250MCH
2016Signaling Pathways in MDS1R01DK107286-01A1 · under PAS-16-033LIN, SHUOSAKAMOTO, KATHLEEN MSTANFORD UNIVERSITY, CA$363,278ZRG1
2016The molecular mechanism of clonal dominance in 5q(del) MDS1R01DK107615-01A1 · under PAS-13-031QIAN, ZHIJIANUNIVERSITY OF ILLINOIS AT CHICAGO, IL$359,775MCH
2016Rcor1 Regulates Myelomonocytic Progenitor Cell Fate1R01DK109694-01A1 · under PAS-16-033FLEMING, WILLIAM HOREGON HEALTH & SCIENCE UNIVERSITY, OR$346,500MCH
2016U2AF1 mutations in myelodysplastic syndromes: from mechanism to therapy1R01DK103854-01A1 · under PAS-13-031BRADLEY, ROBERT KFRED HUTCHINSON CANCER RESEARCH CENTER, WA$341,375ZRG1
2016Hematopoietic Regulation via GATA Switches2R01DK068634-11 · under PAS-13-031BRESNICK, EMERY HUNIVERSITY OF WISCONSIN-MADISON, WI$340,434MCH
2016The Role of Long Noncoding RNA in Hematopoiesis1R01DK110108-01 · under PAS-13-031HUANG, SUMINGUNIVERSITY OF FLORIDA, FL$337,500MCH
2016Metabolic regulation of hematopoietic stem cells2R01DK092722-05 · under PAS-13-031QU, CHENG-KUIEMORY UNIVERSITY, GA$273,000MCH
2015MicroRNAs and hematopoietic differentiation2R01DK068348-11 · under PAS-13-031LODISH, HARVEY FWHITEHEAD INSTITUTE FOR BIOMEDICAL RES, MA$500,175MCH
2015Regulation of hematopoietic stem cell self-renewal by GTPase activating protein signaling1R01DK102890-01A1 · under PAS-13-031FILIPPI, MARIE-DOMINIQUEMALIK, PUNAMCINCINNATI CHILDRENS HOSP MED CTR, OH$426,291ZRG1
2015Regulatory role of iron transport in stress and ineffective erythropoiesis1R01DK107670-01 · under PAS-13-031GINZBURG, YELENANEW YORK BLOOD CENTER, NY$369,573MCH
2015Role of Transcription Pausing in Hematopoietic Stem Cell Development1R01DK105287-01 · under PAS-13-031BAI, XIAOYINGUT SOUTHWESTERN MEDICAL CENTER, TX$354,487MCH
2015Role of the Hypoxia-Inducible Factor-1alpha in Myelodysplastic Syndromes1R01DK105014-01 · under PAS-13-031HUANG, GANGCINCINNATI CHILDRENS HOSP MED CTR, OH$351,000MCH
2015EPIGENTIC REGULATION OF HEMATOPOIETIC STEM CELL FUNCTION AND TRANSFORMATION1R01DK102428-01A1 · under PAS-13-031CHALLEN, GRANT ANTHONYWASHINGTON UNIVERSITY, MO$343,125MCH
2015Roles of Neogenin and Matriptase-2 in Hemojuvelin-Mediated Hepcidin Expression1R01DK102791-01A1 · under PAS-13-031ZHANG, AN-SHENGOREGON HEALTH & SCIENCE UNIVERSITY, OR$332,264MCH
2015Regulation of hematopoietic stem and progenitor cell fate determination by Dpy301R01DK105531-01A1 · under PAS-13-031JIANG, HAOUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$330,750MCH
2015Noncoding RNA-DNMT1 interactions in hematopoiesis1R01DK103858-01 · under PAS-13-031TENEN, DANIEL GBETH ISRAEL DEACONESS MEDICAL CENTER, MA$261,000MCH
2015Quantitative Notch Signaling in Hematopoiesis1R56DK104063-01A1 · under PAS-13-031BERNSTEIN, IRWIN DFRED HUTCHINSON CANCER RESEARCH CENTER, WA$140,800MCH
2015The role of a lincRNA in chromatin structure and hematopoiesis1R56DK101994-01A1 · under PAS-13-031HUANG, SUMINGUNIVERSITY OF FLORIDA, FL$120,000ZRG1
2014Confounder-Corrected Quantitative MRI Biomarkers of Hepatic1R01DK100651-01 · under PAS-13-031REEDER, SCOTT B.UNIVERSITY OF WISCONSIN-MADISON, WI$698,355ZRG1
2014Uncovering the role for Msi2 in hematopoietic stem cells1R01DK101989-01A1 · under PAS-13-031KHARAS, MICHAELSLOAN-KETTERING INST CAN RESEARCH, NY$394,706MCH
2014Epigenetic and Cell Cycle Functions of Glucocorticoids in Erythropoietic Stress1R01DK100915-01A1 · under PAS-13-031SOCOLOVSKY, MERAVUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$361,812MCH
2014Novel regulators of stress erythropoiesis2R01DK089439-04A1 · under PAS-13-031WOJCHOWSKI, DON MICHAELMAINEHEALTH, ME$360,110MCH
2014Dissection and Manipulation of the Cellular Response to Iron Restriction2R01DK079924-05A1 · under PAS-13-031GOLDFARB, ADAM N.UNIVERSITY OF VIRGINIA, VA$343,650INMP
2014HRI-eIF2a Phosphorylation signaling in oxidative stress and erythropoiesis2R01DK087984-04A1 · under PAS-13-031CHEN, JANE-JANEMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$339,300MCH
2014Molecular Determinants of Asymmetric Division1R01DK099335-01A1 · under PAS-13-031REYA, TANNISHTHAUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$337,125MCH
2014The role of emergency granulopoiesis in the pathogenesis of Fanconi Anemia1R01DK098812-01A1 · under PAS-13-031EKLUND, ELIZABETH ANNNORTHWESTERN UNIVERSITY AT CHICAGO, IL$336,038MCH
2014Gradient Biomaterials to Investigate Niche Regulation of Hematopoiesis1R01DK099528-01A1 · under PAS-13-031HARLEY, BRENDAN A.UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$335,859BTSS
2014ZIP Proteins and Iron Metabolism2R01DK080706-06 · under PAS-13-031KNUTSON, MITCHELL DUNIVERSITY OF FLORIDA, FL$314,986INMP
2014BMP4 Dependent Stress Erythropoiesis Pathway in Short-term Radioprotection2R01DK080040-05A1 · under PAS-13-031PAULSON, ROBERT FRANKPENNSYLVANIA STATE UNIVERSITY, THE, PA$311,223MCH
2014Epigenetic regulation by microRNA of MDS pathogenesis1R01DK100689-01 · under PAS-13-031ITO, KEISUKEALBERT EINSTEIN COLLEGE OF MEDICINE, NY$250,500MCH
2014Non-cell-autonomous hedgehog signaling in B lymphopoiesis1R01DK099188-01A1 · under PAS-13-031DESIDERIO, STEPHEN VJOHNS HOPKINS UNIVERSITY, MD$243,000MCH
2014Molecular Pathogenesis of MDS1R01DK102759-01 · under PAS-13-031STARCZYNOWSKI, DANIELCINCINNATI CHILDRENS HOSP MED CTR, OH$234,000MCH
2014U2AF1 mutations in myelodysplastic syndromes: from mechanism to therapy1R56DK103854-01 · under PAS-13-031BRADLEY, ROBERT KFRED HUTCHINSON CANCER RESEARCH CENTER, WA$114,400ZRG1

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