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NIH funding notice RFA-CA-27-002

Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)

Closed on November 10, 2026.

Posted
June 3, 2026
Close date
November 10, 2026
Activity codes
R33
Institutes taking part
NCI

Read the notice on Grants.gov

The notices it replaced

  1. Reissues: RFA-CA-25-002 Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)
  2. 2 steps back: RFA-CA-24-009 Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)
  3. 3 steps back: RFA-CA-23-003 Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)
  4. 4 steps back: RFA-CA-22-002 Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)
  5. 5 steps back: RFA-CA-21-004 Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)
  6. 6 steps back: RFA-CA-20-018 Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33 Clinical Trials Not Allowed)
  7. 7 steps back: RFA-CA-19-020 Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33 Clinical Trials Not Allowed)
  8. 8 steps back: RFA-CA-18-003 Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33 - Clinical Trial Not Allowed)
  9. 9 steps back: RFA-CA-17-011 Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33)
  10. 10 steps back: RFA-CA-16-002 Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33)
  11. 11 steps back: RFA-CA-15-003 Advanced Development and Validation of Emerging Molecular Analysis Technologies for Cancer Research (R33)
  12. 12 steps back: RFA-CA-14-004 Validation and Advanced Development of Emerging Molecular Analysis Technologies for Cancer Research (R33)
  13. 13 steps back: RFA-CA-13-002 Validation and Advanced Development of Emerging Molecular Analysis Technologies for Cancer Research (R33)
  14. 14 steps back: RFA-CA-12-003 Validation and Advanced Development of Emerging Technologies for Cancer Research (R33)
  15. 15 steps back: RFA-CA-10-004 Validation and Advanced Development of Emerging Technologies for Cancer Research (R33)
  16. 16 steps back: RFA-CA-09-007 Application and Use of Transformative Emerging Technologies in Cancer Research (R33)
  17. 17 steps back: RFA-CA-08-008
  18. 18 steps back: RFA-CA-07-036
  19. 19 steps back: RFA-CA-07-018
  20. 20 steps back: RFA-CA-07-002
  21. 21 steps back: RFA-CA-06-003
  22. 22 steps back: RFA-CA-05-003

Who won it before

128 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $54,765,579 in first-year total cost, median $391,290.

Most frequent study sections

  1. Special Emphasis Panel[ZCA1 TCRB-J (M1)]15
  2. Special Emphasis Panel[ZCA1 TCRB-J (J1)]14
  3. Special Emphasis Panel[ZCA1 TCRB-Q (O2)]13
  4. Special Emphasis Panel[ZCA1 TCRB-D (O1)]11
  5. Special Emphasis Panel[ZCA1 TCRB-D (M1)]9

Most frequent institutions

  1. UNIVERSITY OF WASHINGTON6
  2. YALE UNIVERSITY6
  3. ARIZONA STATE UNIVERSITY-TEMPE CAMPUS4
  4. MASSACHUSETTS INSTITUTE OF TECHNOLOGY4
  5. STANFORD UNIVERSITY4
Competing awards under RFA-CA-27-002 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025Single-cell (phospho-)proteomics platform for functional analysis of tumor microenvironment1R33CA287139-01A1 · under RFA-CA-24-009SHI, TUJINBATTELLE PACIFIC NORTHWEST LABORATORIES, WA$450,904ZCA1
2025Advanced Development of Patient Ascites Therapeutic Response Biosensors1R33CA291166-01A1 · under RFA-CA-24-009BOEHM, JESSE SAMUELCIMINI, BETHKLEMPNER, SAMUEL JMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$419,133ZCA1
2025Precision single-cell mapping of chromatin-associated protein activity by molecular footprinting to chart disruptions to gene regulation and dissect tumor heterogeneity in cancer1R33CA302607-01 · under RFA-CA-24-009LANDAU, DANWEILL MEDICAL COLL OF CORNELL UNIV, NY$401,829ZCA1
2025Microbiome-Mediated Tumor Immunomodulation in a Pathomimetic Colorectal Cancer Chip1R33CA286797-01A1 · under RFA-CA-24-009KIM, HYUN JUNGCLEVELAND CLINIC LERNER COM-CWRU, OH$400,890ZCA1
2025Sequence optimization for mRNA cancer therapy1R33CA286947-01A1 · under RFA-CA-24-009SEELIG, GEORGUNIVERSITY OF WASHINGTON, WA$380,337ZCA1
2025Spatiomolecular Profiling of Human Cancer at Scale1R33CA297902-01A1 · under RFA-CA-24-009CHEVRIER, NICOLASUNIVERSITY OF CHICAGO, IL$372,628ZCA1
2025Efficient, cost-effective, and ultrasensitive sequencing of somatic mutations and methylation1R33CA302385-01 · under RFA-CA-24-009SALIPANTE, STEPHEN JUNIVERSITY OF WASHINGTON, WA$369,468ZCA1
2025Next generation platforms for interrogating TCR specificity1R33CA302206-01 · under RFA-CA-24-009GARCIA, KENAN CHRISTOPHERSTANFORD UNIVERSITY, CA$368,294ZCA1
2024A platform for multi-modal single nucleus spatial genomics for molecular tumor analysis1R33CA291199-01 · under RFA-CA-23-003CHEN, FEIBROAD INSTITUTE, INC., MA$417,586ZCA1
2024Nano-CRISPR extracellular vesicle sensing system for longitudinal tumor monitoring1R33CA281794-01A1 · under RFA-CA-23-003IM, HYUNGSOONMASSACHUSETTS GENERAL HOSPITAL, MA$415,830ZCA1
2024Enabling in vivo barcoded single-cell multiomics-compatible genome-wide screens in personalized tumor models using defined-copy somatic transgenesis1R33CA278564-01A1 · under RFA-CA-23-003BREUNIG, JOSHUA JOHNCEDARS-SINAI MEDICAL CENTER, CA$414,491ZCA1
2024An integrated functional proteomics platform for accelerated discovery of isoform-specific determinants of cancer1R33CA281919-01A1 · under RFA-CA-23-003SHEYNKMAN, GLORIAYI, S. STEPHENUNIVERSITY OF VIRGINIA, VA$412,365ZCA1
2024Bio-orthogonal Mid-Infrared Photothermal Imaging of Cancer Metabolism1R33CA287046-01A1 · under RFA-CA-23-003CHENG, JI-XINBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$407,113ZCA1
2024Develop and validate demineralized bone paper-based human bone metabolic and senolytic assays1R33CA291301-01 · under RFA-CA-23-003LEE, JUNGWOOUNIVERSITY OF MASSACHUSETTS AMHERST, MA$394,482ZCA1
2024High Throughput Digital Droplet Assays for Ultrasensitive Multimodal (DNA, RNA, and Protein) Diagnostics1R33CA287135-01 · under RFA-CA-23-003ISSADORE, DAVID AARONUNIVERSITY OF PENNSYLVANIA, PA$389,746ZCA1
2024Spatial protein-protein interaction networks in situ by multiplexed proximity ligation1R33CA291197-01 · under RFA-CA-23-003COSKUN, AHMET F.GEORGIA INSTITUTE OF TECHNOLOGY, GA$374,123ZCA1
2024Quantification of molecular interactions across the matrix spectrum enables cancer research.1R33CA291185-01 · under RFA-CA-23-003BORNHOP, DARRYL J.VANDERBILT UNIVERSITY, TN$335,944ZCA1
20243D Proteomics at Single Cell Resolution with Covalent Protein Painting (CPP)1R33CA272339-01A1 · under RFA-CA-23-003YATES III, JOHN RSCRIPPS RESEARCH INSTITUTE, THE, CA$240,092ZCA1
2023Clonal analysis of cancer by mitochondrial DNA barcoding1R33CA278393-01 · under RFA-CA-22-002SANKARAN, VIJAY GANESHVAN GALEN, PETERBRIGHAM AND WOMEN'S HOSPITAL, MA$462,970ZCA1
2023A platform to identify in vivo targets of covalent cancer drugs in 3D tissues1R33CA281918-01 · under RFA-CA-22-002CRAVATT, BENJAMIN FYE, LISCRIPPS RESEARCH INSTITUTE, THE, CA$450,690ZCA1
2023Advanced development of composite gene delivery and CAR engineering systems1R33CA281702-01 · under RFA-CA-22-002CHEN, SIDIYALE UNIVERSITY, CT$417,075ZCA1
2023Bioorthogonal probe development for highly parallel in vivo imaging1R33CA277820-01 · under RFA-CA-22-002WEISSLEDER, MD, PHD, RALPHMASSACHUSETTS GENERAL HOSPITAL, MA$415,830ZCA1
2023Rapid, simple, and ultrasensitive quantitation of KRAS ctDNA at the point of care using CRISPR/Cas amplification and digital resolution biosensor microscopy1R33CA272271-01A1 · under RFA-CA-22-002CUNNINGHAM, BRIAN T.MANSFIELD, AARON SCOTTWANG, XINGUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$391,467ZCA1
2023Multiplex In-Solution Protein Array (MISPA) for high throughput, quantitative, early profiling of pathogen-induced head and neck1R33CA281802-01 · under RFA-CA-22-002LABAER, JOSHUAARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$390,906ZCA1
2023Combining Machine Learning and Nanofluidic Technology for The Multiplexed Diagnosis of Pancreatic Adenocarcinoma1R33CA278551-01 · under RFA-CA-22-002CARPENTER, ERICAISSADORE, DAVID AARONUNIVERSITY OF PENNSYLVANIA, PA$388,274ZCA1
2023Engineering Protein Modulators of Notch Activation for T-cell immunotherapy1R33CA272331-01A1 · under RFA-CA-22-002GORDON, WENDY RYANMURETTA, JOSEPH M.UNIVERSITY OF MINNESOTA, MN$384,750ZCA1
2023Single cell modeling of cancer mutations1R33CA278469-01 · under RFA-CA-22-002JI, HANLEE PSTANFORD UNIVERSITY, CA$375,297ZCA1
2023A High-Throughput Screening Platform to Discover RNA Methylation Inhibitors1R33CA281602-01 · under RFA-CA-22-002MEYER, KATHRYN DDUKE UNIVERSITY, NC$372,790ZCA1
2023Micro-capsules for versatile multiplexed cytometry1R33CA278392-01 · under RFA-CA-22-002KLEIN, ALLON MOSHEMAZUTIS, LINASHARVARD MEDICAL SCHOOL, MA$370,215ZCA1
2022Systematic characterization of cancer variants using single-cell functional genomics1R33CA267221-01 · under RFA-CA-21-004LOWE, SCOTT W.NORMAN, THOMAS MAXWELLSLOAN-KETTERING INST CAN RESEARCH, NY$440,728ZCA1
2022A low-cost, multiplexed digital high resolution melt platform for DNA methylation-based detection and identification of cancers in liquid biopsies1R33CA272321-01 · under RFA-CA-21-004PISANIC II, THOMAS RUSSELLWANG, TZA-HUEI JEFFJOHNS HOPKINS UNIVERSITY, MD$433,765ZCA1
2022A highly sensitive linear amplification based DNA methylation profiling technique for clinical cancer research1R33CA269100-01 · under RFA-CA-21-004CHIU, BRIAN C-HZHANG, WEIUNIVERSITY OF CHICAGO, IL$421,166ZCA1
2022Expanding the GoT toolkit to link single-cell clonal genotypes with protein, transcriptomic, epigenomic and spatial phenotypes1R33CA267219-01A1 · under RFA-CA-21-004LANDAU, DANWEILL MEDICAL COLL OF CORNELL UNIV, NY$419,174ZCA1
2022Transfer RNA sequencing and application to cancer research and clinics1R33CA272357-01 · under RFA-CA-21-004BISSONNETTE, BRUCE MARCPAN, TAOSHOGAN, BENJAMINUNIVERSITY OF CHICAGO, IL$405,277ZCA1
2022Optogenetic Control of Tumor Initiation and Tumor Progression in vivo1R33CA258012-01A1 · under RFA-CA-21-004KARGINOV, ANDREI VREHMAN, JALEESUNIVERSITY OF ILLINOIS AT CHICAGO, IL$403,638ZCA1
2022Advanced development and validation of an in vitro platform to phenotype brain metastatic tumor cells using artificial intelligence1R33CA261696-01A1 · under RFA-CA-21-004MERAJVER, SOFIA DIANAOLIVER, CHRISTOPHER RYANUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$388,438ZCA1
2022Accessible high-throughput single-cell genome sequencing1R33CA269015-01 · under RFA-CA-21-004ADEY, ANDREWOREGON HEALTH & SCIENCE UNIVERSITY, OR$379,328ZCA1
2022A synthetic toolkit for the recombinant production of tyrosine phosphorylated proteins and peptides1R33CA259451-01A1 · under RFA-CA-21-004NAEGLE, KRISTEN MUNIVERSITY OF VIRGINIA, VA$378,839ZCA1
2022Single-Cell Protein Activity Profiling in Breast Cancer Cells and Tissues1R33CA269094-01 · under RFA-CA-21-004MOELLERING, RAYMOND EUNIVERSITY OF CHICAGO, IL$373,510ZCA1
2022Microfluidic Precision Engineered Artificial Antigen Presenting Cells for Cancer Immunotherapy1R33CA267258-01A1 · under RFA-CA-21-004AGRAWAL, ANSHULEE, ABRAHAM PUNIVERSITY OF CALIFORNIA-IRVINE, CA$367,506ZCA1
2022Targeted Isolation and Identification of Sialylated Glycoproteins in Cancer Tissues, Cells and Biofluids1R33CA267226-01 · under RFA-CA-21-004DRAKE, RICHARD R.MEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$337,036ZCA1
2021Liquid biopsy-based toolkits for neoantigen and cognate TCR discovery for cancer immunotherapy1R33CA256112-01A1 · under RFA-CA-20-018WEI, WEIINSTITUTE FOR SYSTEMS BIOLOGY, WA$462,881ZCA1
2021Joint receptor and protein expression immunophenotyping through split-pool barcoding1R33CA255893-01 · under RFA-CA-20-018SEELIG, GEORGUNIVERSITY OF WASHINGTON, WA$427,567ZCA1
2021Universal Sample Multiplexing for Single Cell Analysis1R33CA247744-01A1 · under RFA-CA-20-018GARTNER, ZEV JORDANUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$398,629ZCA1
2021Mapping Cancer Metabolism by Mid-infrared Photothermal Microscopy1R33CA261726-01 · under RFA-CA-20-018CHENG, JI-XINBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$398,440ZCA1
2021A streamlined, high-throughput platform for validation of cancer antigen presentation and isolation of cancer antigen reactive T cells1R33CA256086-01A1 · under RFA-CA-20-018BROCK, AMYJIANG, NING JENNYUNIVERSITY OF PENNSYLVANIA, PA$394,894ZCA1
2021Validating Urine Derived Cancer Cells (UDCC) -- Non-Invasive and Living Liquid Biopsies -- in Bladder Cancer Clinics1R33CA258016-01 · under RFA-CA-20-018LIU, XUEFENGOHIO STATE UNIVERSITY, OH$390,660ZCA1
2021Super-resolution microscopy for dynamic analysis of focal enhancer amplifications in cancer1R33CA257878-01 · under RFA-CA-20-018HANSEN, ANDERS SEJRMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$379,981ZCA1
2021Multimodal iterative sequencing of cancer genomes and single tumor cells1R33CA247700-01A1 · under RFA-CA-20-018JI, HANLEE PSTANFORD UNIVERSITY, CA$365,977ZCA1
2021Multimodality X-ray transmission and diffraction scanner for molecular analysis of cancer specimens1R33CA256102-01 · under RFA-CA-20-018GREENBERG, JOELKAPADIA, ANUJ J.DUKE UNIVERSITY, NC$360,935ZCA1
2021Integrative Functional Profiling of Tumor-Derived Extracellular Vesicles1R33CA252158-01A1 · under RFA-CA-20-018XU, LIANGZENG, YONGUNIVERSITY OF FLORIDA, FL$354,506ZCA1
2020T-cell Biofactories for targeting extracellular matrix1R33CA247739-01 · under RFA-CA-19-020BHATNAGAR, PARIJATSRI INTERNATIONAL, CA$1,606,207ZCA1
2020Advancing Ultra Long-read Sequencing and Chromatin Interaction Analyses for Chromosomal and Extrachromosomal Structural Variation Characterization in Cancer1R33CA236681-01A1 · under RFA-CA-19-020VERHAAK, ROEL GWWEI, CHIA-LINJACKSON LABORATORY, ME$1,377,810ZCA1
2020Comprehensive breakpoint analyses for simultaneous quantification of all DNA double strand break repair pathways1R33CA236670-01A1 · under RFA-CA-19-020HIGGINSON, DANIELSLOAN-KETTERING INST CAN RESEARCH, NY$1,322,190ZCA1
2020Multiplexed imaging of chromatin folding and RNA profiles in cancer1R33CA251037-01 · under RFA-CA-19-020MUZUMDAR, MANDAR DEEPAKWANG, SIYUANYALE UNIVERSITY, CT$1,237,899ZCA1
2020Detecting diverse nucleic acid biomarkers of cancer with solid-state nanopores1R33CA246448-01A1 · under RFA-CA-19-020HALL, ADAM ROGERWAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$1,089,730ZCA1
2020High-Throughput Screening Platform for Cancer Drug Discovery1R33CA240191-01A1 · under RFA-CA-19-020RECHT, MICHAELPALO ALTO RESEARCH CENTER, CA$720,575ZCA1
2020Clinical implementations of spatial transcriptomics in tumors1R33CA246455-01 · under RFA-CA-19-020ASHENBERG, ORRCHEN, FEIRODIG, SCOTT JBROAD INSTITUTE, INC., MA$449,518ZCA1
2020High-throughput single-cell co-sequencing of small and large RNAs to identify molecular circuitry in cancer1R33CA246711-01 · under RFA-CA-19-020FAN, RONGLU, JUNYALE UNIVERSITY, CT$417,077ZCA1
2020Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer using Pathology Biopsies1R33CA240181-01A1 · under RFA-CA-19-020CHAICHANA, KAISORN LEECOOKS, ROBERT GRAHAMQUINONES-HINOJOSA, ALFREDOPURDUE UNIVERSITY, IN$392,146ZCA1
2020A Virion-Display Oscillator Array and Detection Platform for Quantification of Transmembrane Protein Binding Kinetics1R33CA235294-01A1 · under RFA-CA-19-020WANG, SHAOPENGARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$391,113ZCA1
2020Time-resolved FRET-based allostery sensors for any protein kinase drug target1R33CA246363-01 · under RFA-CA-19-020LEVINSON, NICHOLAS MARKUNIVERSITY OF MINNESOTA, MN$375,535ZCA1
2019A High Throughput Human Tumor Modeling Technology for Cancer Drug Discovery1R33CA225549-01A1 · under RFA-CA-18-003LUKER, GARY DTAVANA, HOSSEINUNIVERSITY OF AKRON, OH$476,844ZCA1
2019A high-throughput nanoparticle assay to characterize cancer neoepitope-specific T cells1R33CA229042-01A1 · under RFA-CA-18-003SCHNECK, JONATHAN PJOHNS HOPKINS UNIVERSITY, MD$416,450ZCA1
2019GESTALT Barcoding and Single-cell Transcriptomics of Tumor Cell Evolution in Personalized Tumor Models1R33CA236687-01 · under RFA-CA-18-003BREUNIG, JOSHUA JOHNCEDARS-SINAI MEDICAL CENTER, CA$413,100ZCA1
2019Advanced Development of the MasSpec Pen for Cancer Diagnosis and Surgical Margin Evaluation1R33CA229068-01A1 · under RFA-CA-18-003SCHIAVINATO EBERLIN, LIVIAUNIVERSITY OF TEXAS AT AUSTIN, TX$411,941ZCA1
2019Multi-color Mapping of Cancer Molecular Signatures and Tumor microenvironment1R33CA235319-01A1 · under RFA-CA-18-003YANG, JENNY J.GEORGIA STATE UNIVERSITY, GA$407,268ZCA1
2019Rapidly scalable platforms for direct in vivo screening of functional drivers in lethal cancers1R33CA225498-01A1 · under RFA-CA-18-003CHEN, SIDIYALE UNIVERSITY, CT$407,025ZCA1
2019Activity based profiling of Phosphoprotein phosphatases in cancer using mass spectrometry-based proteomics1R33CA225458-01A1 · under RFA-CA-18-003GERBER, SCOTT A.KETTENBACH, ARMINJA NADINEDARTMOUTH COLLEGE, NH$400,114ZCA1
2019Optimization and validation of integrated microscale technologies for low-cost, automated production of PET molecular imaging tracers for cancer research1R33CA240201-01 · under RFA-CA-18-003VAN DAM, ROBERT MICHAELUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$379,082ZCA1
2019Spatially Resolved Metagenomics to Explore Tumor-Microbiome Interactions in Human Colorectal Cancer1R33CA235302-01A1 · under RFA-CA-18-003BRITO, ILANA LAURENDE VLAMINCK, IWIJNZIPFEL, WARREN RCORNELL UNIVERSITY, NY$349,262ZCA1
2019Multiscale microscope for 3D cancer imaging in model organisms and organoids1R33CA235254-01 · under RFA-CA-18-003FIOLKA, RETO PAULUT SOUTHWESTERN MEDICAL CENTER, TX$328,541ZCA1
2019Increased Sensitivity of Minimal Residual Disease Monitoring using Peripheral Blood in Pediatric Patients with Acute Lymphoblastic Leukemia1R33CA235597-01A1 · under RFA-CA-18-003AUGUST, KEITHSOPER, STEVEN ALLANUNIVERSITY OF KANSAS LAWRENCE, KS$241,587ZCA1
2018Pro-Codes: A novel vector and cell barcoding technology1R33CA223947-01A1 · under RFA-CA-17-011BROWN, BRIAN DICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$421,587ZCA1
2018Determining treatment sensitivity in B cell lymphoma by novel microfluidics-based NK cell immunogenicity platform1R33CA223908-01 · under RFA-CA-17-011EVENS, ANDREW MHUANG, TONY JUNKONRY, TANIA TALINORTHEASTERN UNIVERSITY, MA$421,501ZCA1
2018Advanced development and validation of microdevices for high-throughput in situ drug sensitivity testing in tumors1R33CA223904-01 · under RFA-CA-17-011CIMA, MICHAEL JMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$416,667ZCA1
2018An integrated therapeutic T cell receptor screening platform for adoptive cell therapy in cancer1R33CA225539-01 · under RFA-CA-17-011JIANG, NING JENNYUNIVERSITY OF TEXAS AT AUSTIN, TX$396,959ZCA1
2018CRISPR-based Enhanced Molecular Chipper Technology for Identifying Functional Noncoding Elements in Cancer1R33CA225863-01 · under RFA-CA-17-011LU, JUNYALE UNIVERSITY, CT$395,674ZCA1
2018Quantitative SRS Imaging of Cancer Metabolism at Single Cell Level1R33CA223581-01A1 · under RFA-CA-17-011CHENG, JI-XINBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$390,880ZCA1
2018Optimization and Validation of Single-Molecule Kinetic Fingerprinting Technology for Rapid, Ultra-Specific Detection of Cancer Mutations1R33CA229023-01 · under RFA-CA-17-011TEWARI, MUNEESHWALTER, NILS GUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$388,440ZCA1
2018Multiplex matrix ELISA for T cell protein-interaction networks in cancer1R33CA228979-01 · under RFA-CA-17-011SCHRUM, ADAM G.UNIVERSITY OF MISSOURI-COLUMBIA, MO$387,880ZCA1
2018Advanced development and validation of genome-scale molecular diagnostics for microsatelliteinstability using targeted molecular counting methods1R33CA222344-01 · under RFA-CA-17-011SALIPANTE, STEPHEN JUNIVERSITY OF WASHINGTON, WA$386,677ZCA1
2018High-throughput super-resolution imaging of chromatin structures at different epigenetic states1R33CA225494-01 · under RFA-CA-17-011LIU, YANGUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$351,864ZCA1
2017Maximum efficiency sequencing using nuclease-based mutation enrichment and digital barcodes1R33CA217652-01 · under RFA-CA-16-002MAKRIGIORGOS, G. MIKEDANA-FARBER CANCER INST, MA$456,746ZCA1
2017Measurement of Aberrant Protein Folds in Malignant Cells with Proteomics and Mass Spectrometry1R33CA212973-01 · under RFA-CA-16-002YATES III, JOHN RSCRIPPS RESEARCH INSTITUTE, THE, CA$435,649ZCA1
2017Droplet microfluidic technology for single cell cancer genomics1R33CA212697-01 · under RFA-CA-16-002KLEIN, ALLON MOSHEHARVARD MEDICAL SCHOOL, MA$411,954ZCA1
2017High Resolution High Throughput Proteomics Platform for Cancer Research1R33CA217699-01 · under RFA-CA-16-002IBRAHIM, YEHIABATTELLE PACIFIC NORTHWEST LABORATORIES, WA$410,858ZCA1
2017Integrated exosomes profiling for minimally invasive diagnosis and monitoring of cancer1R33CA214333-01 · under RFA-CA-16-002GODWIN, ANDREW K.SAMUEL, GLENSONZENG, YONGUNIVERSITY OF KANSAS LAWRENCE, KS$400,098ZCA1
2017Next-generation MOWChIP-seq for high-throughput epigenomic profiling using clinically relevant samples1R33CA214176-01 · under RFA-CA-16-002LU, CHANGVIRGINIA POLYTECHNIC INST AND ST UNIV, VA$391,723ZCA1
2017TARGETED SINGLE-MOLECULE SEQUENCING ASSAY INCORPORATING MOLECULAR BARCODES1R33CA217700-01 · under RFA-CA-16-002DUNCAVAGE, ERIC JWALTER, MATTHEW JWASHINGTON UNIVERSITY, MO$379,725ZCA1
2017Multiplex FRET Imaging of Kinase-Epigenome Interregulations in Live Cancer Cells1R33CA204704-01A1 · under RFA-CA-16-002WANG, YINGXIAOUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$376,821ZCA1
2017Cancer histology and QC via MUSE: Sample-sparing UV surface-excitation microscopy1R33CA202881-01A1 · under RFA-CA-16-002LEVENSON, RICHARD M.UNIVERSITY OF CALIFORNIA AT DAVIS, CA$373,637ZCA1
2017LETSSGo: Lymphoma-on-chip Engineered Technology for Single-Organoid Sequencing and Genomics1R33CA212968-01 · under RFA-CA-16-002SINGH, ANKURCORNELL UNIVERSITY, NY$371,216ZCA1
2017Fluorescence lifetime-based single fluorophore biosensors of post-translational modification enzyme activity1R33CA217780-01 · under RFA-CA-16-002PARKER, LAURIE L.UNIVERSITY OF MINNESOTA, MN$345,244ZCA1
2017Development and validation of nanoparticle-mediated microfluidic profiling approach for rare cell analysis1R33CA204574-01A1 · under RFA-CA-16-002KELLEY, SHANA OUNIVERSITY OF TORONTO, ON$258,952ZCA1
2016Advanced Development and Validation of 3 Dimensional Spheroid Culture of Primary Cancer Cells using Nano3D Technology1R33CA206949-01 · under RFA-CA-15-003SPICER, TIMOTHY PATRICKSCRIPPS FLORIDA, FL$501,426ZCA1
2016Clinical implementation of single cell tumor transcriptome analysis1R33CA202820-01 · under RFA-CA-15-003REGEV, AVIVBROAD INSTITUTE, INC., MA$457,465ZCA1
2016Analysis of scant cancer cells in fine needle aspirates1R33CA202064-01 · under RFA-CA-15-003WEISSLEDER, MD, PHD, RALPHMASSACHUSETTS GENERAL HOSPITAL, MA$433,261ZCA1
2016A Genetic Toolbox for the Identification and Interrogation of Tumor Cells of Origin, Propagation, and Recurrence From Patient-derived Oncogenic Drivers1R33CA202900-01 · under RFA-CA-15-003BREUNIG, JOSHUA JOHNCEDARS-SINAI MEDICAL CENTER, CA$418,128ZCA1
2016Validating Rapid Microfluidic Isolation of Personalized Aptamers for Monitoring Minimal Residual Disease in Multiple Myeloma1R33CA196470-01A1 · under RFA-CA-15-003LIN, QIAOCOLUMBIA UNIV NEW YORK MORNINGSIDE, NY$394,518ZCA1
2016Translational Molecular and Cellular Imaging Technologies for Prostate Tumor Pathology1R33CA196458-01A1 · under RFA-CA-15-003BHARGAVA, ROHITCHEVILLE, JOHN CUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$387,693ZCA1
2016Charge sensitive optical detection for high-throughput study of small molecules1R33CA202834-01A1 · under RFA-CA-15-003TAO, NONGJIANARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$381,382ZCA1
2016Online Raman Diagnostics of Oncometabolites1R33CA206922-01 · under RFA-CA-15-003SCHULTZ, ZACHARYUNIVERSITY OF NOTRE DAME, IN$363,875ZCA1
2016GESI: a novel technology for functional imaging in living cells1R33CA196445-01A1 · under RFA-CA-15-003LAM, KIT SUNIVERSITY OF CALIFORNIA AT DAVIS, CA$362,749ZCA1
2016Protein painting identifies therapeutic targets at protein-protein interfaces1R33CA206937-01 · under RFA-CA-15-003LIOTTA, LANCE ALLENGEORGE MASON UNIVERSITY, VA$348,203ZCA1
2016High Throughput GO Chip isolation of Lung CTCs for Molecular Diagnosis and Drug Testing1R33CA202867-01 · under RFA-CA-15-003NAGRATH, SUNITHARAMNATH, NITHYAUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$343,664ZCA1
2016A novel molecular assay for early detection and assessment of cancer risk1R33CA202898-01 · under RFA-CA-15-003QUEIMADO, LURDESUNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, OK$340,594ZCA1
2016Monitoring Recurrent Bladder Cancer with Electro-Phage Biosensors1R33CA206955-01 · under RFA-CA-15-003WEISS, GREGORY A.UNIVERSITY OF CALIFORNIA-IRVINE, CA$322,131ZCA1
2016Large-Scale Integration of Single Cell RNA-Seq and High-Content Imaging for Analyzing Drug Response in Cancer1R33CA202827-01 · under RFA-CA-15-003SIMS, PETER ALANCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$316,149ZCA1
2016Brillouin confocal microscopy for biomechanical studies of metastatic cascade in 3D microenvironments1R33CA204582-01 · under RFA-CA-15-003SCARCELLI, GIULIANOUNIV OF MARYLAND, COLLEGE PARK, MD$295,733ZCA1
2015Single cell cytokine analysis of circulating malignant hematopoietic cells1R33CA196411-01 · under RFA-CA-14-004FAN, RONGLEVINE, ROSS LYALE UNIVERSITY, CT$421,227ZCA1
2015High-throughput on-chip platform for interrogation of mitochondrial membrane potential and apoptosis1R33CA182384-01A1 · under RFA-CA-14-004BURKE, PETER J.UNIVERSITY OF CALIFORNIA-IRVINE, CA$412,541ZCA1
2015Noninvasive detection of circulating RNAs for lung cancer early detection and prognosis1R33CA191245-01A1 · under RFA-CA-14-004WU, YUNSTATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$411,504ZCA1
2015Development of a virion display (VirD) array to profile human GPCR interactions1R33CA186790-01A1 · under RFA-CA-14-004DESAI, PRASHANT JZHU, HENGJOHNS HOPKINS UNIVERSITY, MD$403,372ZCA1
2015A Cancer Rainbow Mouse for Simultaneous Assessment of Multiple Oncogenes1R33CA191198-01 · under RFA-CA-14-004CARON, MARC G.DUKE UNIVERSITY, NC$389,963ZCA1
2015Using Adductomics to Characterize Exposures to Carcinogens1R33CA191159-01A1 · under RFA-CA-14-004RAPPAPORT, STEPHEN MORRISUNIVERSITY OF CALIFORNIA BERKELEY, CA$380,395ZCA1
2015Advanced development and validation of targeted molecular counting methods for precise and ultrasensitive quantitation of low prevalence somatic mutations1R33CA192980-01 · under RFA-CA-14-004SALIPANTE, STEPHEN JUNIVERSITY OF WASHINGTON, WA$375,858ZCA1
2015Scalable Cancer Genomics via Nanocoding and Sequencing1R33CA182360-01A1 · under RFA-CA-14-004MA, JIANSCHWARTZ, DAVID C.UNIVERSITY OF WISCONSIN-MADISON, WI$372,503ZCA1
2015Fast interference-based super-resolution microscope for cancer mechanobiology1R33CA193043-01 · under RFA-CA-14-004ZIPFEL, WARREN RCORNELL UNIVERSITY, NY$364,273ZCA1
2015Single cell growth assay for residual cells in acute lymphoblastic leukemia1R33CA191143-01 · under RFA-CA-14-004MANALIS, SCOTT RMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$363,946ZCA1
2015RASL-Seq Expression Profiling of FFPE Tissues1R33CA183688-01A1 · under RFA-CA-14-004YEAKLEY, JOANNE MULLIGANBIOSPYDER TECHNOLOGIES, INC., CA$363,706ZCA1
2015Validation and Advanced Development of Glycan Node Analysis in Lung Cancer Research1R33CA191110-01 · under RFA-CA-14-004BORGES, CHAD RARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$317,654ZCA1
2014Integrating mass cytometric and transcriptomic profiles of solid tumors1R33CA183692-01 · under RFA-CA-13-002WEISS, WILLIAM AUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$408,712ZCA1
2014Large-Scale Characterization of Anti-Cancer Antibody Responses in Lung Adenocarci1R33CA183659-01 · under RFA-CA-13-002ROBINSON, WILLIAM HSTANFORD UNIVERSITY, CA$399,643ZCA1
2014Validation and Advanced Development of Duplex Sequencing1R33CA181771-01A1 · under RFA-CA-13-002LOEB, LAWRENCE AUNIVERSITY OF WASHINGTON, WA$384,923ZCA1
2014Validating Technology To Optimize Antibody Affinity For Targeting Therapeutics1R33CA177333-01A1 · under RFA-CA-13-002FEDERSPIEL, MARK JMAYO CLINIC ROCHESTER, MN$375,008ZCA1
2014Non-Circulating Microparticles for Improved Localization and Resection Cancer1R33CA177449-01A1 · under RFA-CA-13-002BLAIR, SARAH LUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$361,766ZCA1
2014Multiplexed Kinase Biosensor Technology to Detect Leukemia Signaling with Mass Sp1R33CA183671-01 · under RFA-CA-13-002PARKER, LAURIE L.UNIVERSITY OF MINNESOTA, MN$341,454ZCA1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-11-0.1.2. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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