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NIH funding notice RFA-HL-23-008

NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional)

Closed on February 28, 2024.

Posted
November 16, 2021
Close date
February 28, 2024
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

Competing awards, new and renewals, since FY2014, under this notice and the notices it replaced.

Past awards
7
7 renewals
Median first-year cost
$999,578
$6,797,391 in all
Institutions
7
7 contact PIs
Patents
1
from 1 funded project

Awards by fiscal year

Fiscal years 2014 to 2026.

Most frequent institutions

  1. ADVENT THERAPEUTICS, INC.1
  2. ANNOVIANT, INC1
  3. DNA MEDICINE INSTITUTE1
  4. HILLHURST BIOPHARMACEUTICALS, INC.1
  5. POLYVASCULAR INC1

and 2 other institutions

Most frequent study sections

  1. Special Emphasis Panel (ZHL1 CSR-O (O3))3
  2. Special Emphasis Panel (ZHL1 CSR-F (O1))2
  3. Special Emphasis Panel (ZHL1 CSR-F (O2))2
7 awards under RFA-HL-23-008 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
FY2025An in vitro diagnostic assay for the early and accurate detection of platelet-activating antibodies associated with Heparin-inducedThrombocytopenia2R44HL147734-04Jones, CurtisRETHAM TECHNOLOGIES, INC., WIFirst-year cost $1,154,002Study section ZHL1
FY2025DUCTUS ARTERIOSUS STENT TO IMPROVE CONGENITAL HEART DEFECT MORTALITY2R44HL158304-04A1Tang, BeverlySTARLIGHT CARDIOVASCULAR, INC., CAFirst-year cost $999,918Study section ZHL1
FY2025Development of a Polymeric Percutaneous Pulmonary Valve for Use in Young Children2R44HL129577-04A1Harrington, Daniel AKhalil, Vivian FikryPOLYVASCULAR INC, TXFirst-year cost $815,391Study section ZHL1
FY2024Hemophilia Point-of-Care Monitoring Device and App2R44HL151147-03Chan, Eugene Yan-HoDNA MEDICINE INSTITUTE, MAFirst-year cost $999,888Study section ZHL1
FY2024Pulmonary Valved Graft with Regeneration Potential for Pediatric Patients2R44HL147771-04Houde, AjayANNOVIANT, INC, GAFirst-year cost $833,493Study section ZHL1
FY2023HBI-002 to Prevent Vaso-Occlusive Crises in Sickle Cell Disease2R44HL131065-05Gomperts, EdwardHILLHURST BIOPHARMACEUTICALS, INC., CAFirst-year cost $999,578Study section ZHL1
FY2023Aerosolized Vitamin A: Developing a Prevention for Hyperoxic Lung Injury and Bronchopulmonary Dysplasia, with Focus on Neonatal Lung Maturation2R44HL142353-04Gelfand, CraigRehan, Virender KADVENT THERAPEUTICS, INC., PAFirst-year cost $995,121Study section ZHL1
Newest fiscal year first, then first-year cost.

Patents from its funded projects

1 patent names 1 of the 7 funded projects.

  1. US 12,366,584 (opens the patent at USPTO, a PDF, in a new tab)IDENTIFICATION OF PLATELET ACTIVATING ANTIBODIESGranted July 22, 2025 to RETHAM TECHNOLOGIES, INC.R44HL147734 · RETHAM TECHNOLOGIES, INC., WI

Each number opens the patent at USPTO, beside the project NIH ties it to and that project's institution. NIH ties a patent to a project, not to a year of its funding, and says its list is incomplete. The grant date and the owners are USPTO's: the organizations the patent names as assignees on the day it was granted. Source: United States Patent and Trademark Office, www.uspto.gov, which does not endorse ScienceDex.

Data: Grants.gov's daily extract and NIH's notice pages, award files and patents file, in ScienceGraph release conductgrants-2026-11-13-0.3.2. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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RFA-HL-23-008: NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional) | ScienceDex | ConductScience