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NIH funding notice RFA-HL-26-002

NHLBI Outstanding Investigator Award (OIA) (R35 Clinical Trial Optional)

Open. Closes April 28, 2027.

Posted
April 26, 2024
Close date
April 28, 2027
Activity codes
R35
Institutes taking part
NHLBI

The notices it replaced

3 notices since 2015, oldest first, each with its awards since FY2014.

  1. Posted 2015RFA-HL-16-02469 awards
  2. Posted 2019RFA-HL-20-01135 awards
  3. Posted 2021RFA-HL-23-00436 awards
  4. Posted 2024RFA-HL-26-002This notice, open · 15 awards

Who won it before

Competing awards, new and renewals, since FY2014, under this notice and the notices it replaced.

Past awards
155
155 new
Median first-year cost
$948,730
$143,450,996 in all
Institutions
66
129 contact PIs
Patents
21
from 15 funded projects

Awards by fiscal year

Fiscal years 2014 to 2026.

Most frequent institutions

  1. COLUMBIA UNIVERSITY HEALTH SCIENCES11
  2. UNIVERSITY OF MICHIGAN AT ANN ARBOR8
  3. UNIVERSITY OF CALIFORNIA LOS ANGELES6
  4. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO6
  5. YALE UNIVERSITY6

and 61 other institutions

Most frequent study sections

  1. Special Emphasis Panel (ZHL1 CSR-I (O1))78
  2. Special Emphasis Panel (ZHL1 CSR-R (O3))37
  3. Special Emphasis Panel (ZHL1 CSR-R (O1))13
  4. Special Emphasis Panel (ZHL1 CSR-I (O2))12
  5. Special Emphasis Panel (ZRG1 RCCS-K (90))6

and 3 other study sections

155 awards under RFA-HL-26-002 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
FY2026Non-coding RNAs and chronic limb threatening ischemia1R35HL183402-01Feinberg, Mark WBRIGHAM AND WOMEN'S HOSPITAL, MAFirst-year cost $1,242,222Study section ZRG1
FY2026Bridging the gap between basic and clinical research to prevent cardiovascular disease in diabetes1R35HL184266-01Bornfeldt, Karin EUNIVERSITY OF WASHINGTON, WAFirst-year cost $1,233,682Study section ZRG1
FY2026A Program Investigating New Concepts ofMacrophage Biology in Atherosclerosis and Atherosclerosis-MASH Cardiometabolic Disease1R35HL183005-01Tabas, Ira ACOLUMBIA UNIVERSITY HEALTH SCIENCES, NYFirst-year cost $1,151,500Study section ZRG1
FY2026Regenerate the lung through a better understanding of development1R35HL184263-01Que, JianwenCOLUMBIA UNIVERSITY HEALTH SCIENCES, NYFirst-year cost $1,151,498Study section ZRG1
FY2026Dynamics and plasticity of the hematopoietic stem cell niche1R35HL184177-01Ding, LeiCOLUMBIA UNIVERSITY HEALTH SCIENCES, NYFirst-year cost $1,137,883Study section ZRG1
FY2026Therapeutic editing for cardiovascular diseases1R35HL183558-01Musunuru, KiranUNIVERSITY OF PENNSYLVANIA, PAFirst-year cost $1,137,435Study section ZRG1
FY2026Regulation of Ubiquitin E3 ligases and Innate Immunity in ARDS1R35HL182842-01Mallampalli, Rama KOHIO STATE UNIVERSITY, OHFirst-year cost $1,102,500Study section ZRG1
FY2026Program to block age-related pulmonary fibrosis and restore lung regeneration1R35HL183538-01Chapman, Harold AUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CAFirst-year cost $1,097,760Study section ZRG1
FY2026Interorganellar Calcium Signaling in Health and Disease1R35HL183468-01Trebak, MohamedUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PAFirst-year cost $1,088,692Study section ZRG1
FY2026Novel pathways and mechanisms underlying disorders of platelet count and/or function1R35HL183547-01Bergmeier, WolfgangUNIV OF NORTH CAROLINA CHAPEL HILL, NCFirst-year cost $1,081,420Study section ZRG1
FY2026Decoding kindlin-3 signaling in platelets and neutrophils1R35HL183465-01Ma, Yan-QingVERSITI BLOOD HEALTH, INC., WIFirst-year cost $1,069,072Study section ZRG1
FY2026Screening and validation of miRNA targets for neurogenic hypertension.1R35HL184169-01Lazartigues, Eric DLSU HEALTH SCIENCES CENTER, LAFirst-year cost $1,008,719Study section ZRG1
FY2026The protein C pathway: Mechanisms, Structure-function, and Translation1R35HL184173-01Mosnier, Laurent OlivierSCRIPPS RESEARCH INSTITUTE, THE, CAFirst-year cost $863,954Study section ZRG1
FY2026Leveraging the nutrient sensing and degradative capacity of lysosomes in macrophages as a novel therapeutic approach in cardiovascular disease1R35HL183548-01Razani, BabakUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PAFirst-year cost $756,607Study section ZRG1
FY2026Decoding the enigma of cardiac arrhythmia and mechanosensitivity1R35HL184262-01Chiamvimonvat, NipavanUNIVERSITY OF ARIZONA, AZFirst-year cost $558,127Study section ZRG1
FY2025Molecular and Translational Studies in Hematologic Disorders1R35HL177719-01 · under RFA-HL-23-004Lopez, Jose AronBLOODWORKS, WAFirst-year cost $1,276,908Study section ZHL1
FY2025Advancing Precision Medicine for ARDS and Sepsis1R35HL177135-01 · under RFA-HL-23-004Calfee, CarolynUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CAFirst-year cost $1,147,992Study section ZHL1
FY2025Locking and Unlocking Cardiac Maturation1R35HL177035-01 · under RFA-HL-23-004Kelly, Daniel PatrickUNIVERSITY OF PENNSYLVANIA, PAFirst-year cost $1,137,498Study section ZHL1
FY2025Macrophages in Cardiovascular Health1R35HL176359-01 · under RFA-HL-23-004Nahrendorf, MatthiasMASSACHUSETTS GENERAL HOSPITAL, MAFirst-year cost $1,127,798Study section ZHL1
FY2025The microenvironment in bone marrow hematopoiesis1R35HL177125-01 · under RFA-HL-23-004Lucas, DanielCINCINNATI CHILDRENS HOSP MED CTR, OHFirst-year cost $1,123,357Study section ZHL1
FY2025Molecular Mechanism and Targeting of Chronic Pain in Sickle Cell Disease1R35HL177406-01 · under RFA-HL-23-004Wang, Zaijie JimUNIVERSITY OF ILLINOIS AT CHICAGO, ILFirst-year cost $1,103,783Study section ZHL1
FY2025The role of cancer in cardiovascular disease1R35HL176060-01 · under RFA-HL-23-004Leeper, Nicholas JamesSTANFORD UNIVERSITY, CAFirst-year cost $1,102,957Study section ZHL1
FY2025Regulation of Intravascular Triglyceride Hydrolysis1R35HL176438-01 · under RFA-HL-23-004Young, Stephen G.UNIVERSITY OF CALIFORNIA LOS ANGELES, CAFirst-year cost $1,102,500Study section ZHL1
FY2025Intersection of the PPARγ-RhoBTB1-Cullin-3 Pathway and Renin-Angiotensin System in Blood Pressure, Vascular Function and Arterial Stiffness1R35HL177123-01 · under RFA-HL-23-004Sigmund, Curt DanielMEDICAL COLLEGE OF WISCONSIN, WIFirst-year cost $1,092,000Study section ZHL1
FY2025Phagocyte Crosstalk in the Balance of Inflammation & Cardiac Disease1R35HL177401-01 · under RFA-HL-23-004Thorp, Edward BenjaminNORTHWESTERN UNIVERSITY, ILFirst-year cost $1,091,824Study section ZHL1
FY2025CD4+ T cell Immunity in the Respiratory Tract1R35HL177381-01 · under RFA-HL-23-004Kolls, Jay KTULANE UNIVERSITY OF LOUISIANA, LAFirst-year cost $1,063,324Study section ZHL1
FY2025Immune crosstalk in lung injury and fibrosis1R35HL176572-01 · under RFA-HL-23-004Moore, Bethany B.UNIVERSITY OF MICHIGAN AT ANN ARBOR, MIFirst-year cost $1,061,189Study section ZHL1
FY2025Promoting weight-related health in the next generation of adolescents and young adults:A comprehensive program of research1R35HL177136-01 · under RFA-HL-23-004Neumark-Sztainer, Dianne RUNIVERSITY OF MINNESOTA, MNFirst-year cost $1,057,905Study section ZHL1
FY2025Targeting Hypoxia-Inducible Factors (HIFs) for Heart and Lung Disease1R35HL177402-01 · under RFA-HL-23-004Eltzschig, Holger K.UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TXFirst-year cost $564,445Study section ZHL1
FY2024Developmental origins of pericyte heterogeneity1R35HL171534-01 · under RFA-HL-23-004Lawson, Nathan DUNIV OF MASSACHUSETTS MED SCH WORCESTER, MAFirst-year cost $1,172,500Study section ZHL1
FY2024Emergency Myelopoiesis in the Control of Blood Production1R35HL171521-01 · under RFA-HL-23-004Passegue, EmmanuelleCOLUMBIA UNIVERSITY HEALTH SCIENCES, NYFirst-year cost $1,131,261Study section ZHL1
FY2024From genetic association to function: pleiotropic novel genes and variants linking lipid metabolism and cardiovascular diseases1R35HL172107-01 · under RFA-HL-23-004Rader, Daniel JamesUNIVERSITY OF PENNSYLVANIA, PAFirst-year cost $1,123,889Study section ZHL1
FY2024Transcriptional and epigenetic mechanisms of alveologenesis and re-alveologenesis1R35HL171346-01 · under RFA-HL-23-004Chen, JichaoCINCINNATI CHILDRENS HOSP MED CTR, OHFirst-year cost $1,122,351Study section ZHL1
FY2024Heterozygous SERPINE1 Deficiency Confers Durable Cardiovascular Fitness in Humans1R35HL171553-01 · under RFA-HL-23-004Vaughan, Douglas ENORTHWESTERN UNIVERSITY AT CHICAGO, ILFirst-year cost $1,114,010Study section ZHL1
FY2024Ion Channels and Membrane Receptors in Pulmonary Arterial Hypertension1R35HL171538-01 · under RFA-HL-23-004Yuan, Jason X JUNIVERSITY OF CALIFORNIA, SAN DIEGO, CAFirst-year cost $1,106,000Study section ZHL1
FY2024Mitofusin 2 as a Nodal Regulator of Mitochondrial Function in Cardiomyopathy1R35HL171080-01 · under RFA-HL-23-004Dorn, Gerald W.WASHINGTON UNIVERSITY, MOFirst-year cost $1,088,500Study section ZHL1
FY2024Cardiovascular potassium channels: From molecular basis to disease therapeutics1R35HL171542-01 · under RFA-HL-23-004Nichols, Colin GWASHINGTON UNIVERSITY, MOFirst-year cost $1,088,500Study section ZHL1
FY2024Neural Control of Breathing1R35HL171451-01 · under RFA-HL-23-004Feldman, Jack LUNIVERSITY OF CALIFORNIA LOS ANGELES, CAFirst-year cost $1,088,345Study section ZHL1
FY2024Molecular and Cellular Regulation of Vascular Calcification1R35HL171342-01 · under RFA-HL-23-004Giachelli, Cecilia MUNIVERSITY OF WASHINGTON, WAFirst-year cost $1,067,521Study section ZHL1
FY2024Mechanisms in Blood Clotting1R35HL171334-01 · under RFA-HL-23-004Morrissey, James H.UNIVERSITY OF MICHIGAN AT ANN ARBOR, MIFirst-year cost $988,138Study section ZHL1
FY2024The Molecular Genetics of Hemostasis1R35HL171421-01 · under RFA-HL-23-004Ginsburg, DavidUNIVERSITY OF MICHIGAN AT ANN ARBOR, MIFirst-year cost $941,106Study section ZHL1
FY2023Inflammation and thrombosis fuel cardiovascular and pulmonary disease: Focus on the interplay of neutrophil inflammasomes with NETs1R35HL166556-01 · under RFA-HL-23-004Wagner, Denisa DBOSTON CHILDREN'S HOSPITAL, MAFirst-year cost $1,239,000Study section ZHL1
FY2023Regulation of Progenitor Cell Plasticity in Lung Development and Disease-Repair1R35HL166661-01 · under RFA-HL-23-004Cardoso, Wellington V.COLUMBIA UNIVERSITY HEALTH SCIENCES, NYFirst-year cost $1,117,873Study section ZHL1
FY2023Decoding innate immune signaling in normal and myelodysplastic hematopoiesis1R35HL166430-01 · under RFA-HL-23-004Starczynowski, DanielCINCINNATI CHILDRENS HOSP MED CTR, OHFirst-year cost $1,113,000Study section ZHL1
FY2023Mechanical Load Effects on Cardiac Function and Heart Diseases1R35HL166575-01 · under RFA-HL-23-004Chen-Izu, YeUNIVERSITY OF CALIFORNIA AT DAVIS, CAFirst-year cost $1,101,935Study section ZHL1
FY2023GPIb-IX and VWF in thrombosis and thrombocytopenia1R35HL166654-01 · under RFA-HL-23-004Li, RenhaoEMORY UNIVERSITY, GAFirst-year cost $1,095,500Study section ZHL1
FY2023Supply and Demand: Oxygen and Workload Regulate Cardiomyocyte Proliferation1R35HL166563-01 · under RFA-HL-23-004Sadek, HeshamUT SOUTHWESTERN MEDICAL CENTER, TXFirst-year cost $1,071,753Study section ZHL1
FY2023Targeted immune therapies in heart transplantation1R35HL166640-01 · under RFA-HL-23-004Abdi, RezaBRIGHAM AND WOMEN'S HOSPITAL, MAFirst-year cost $1,050,893Study section ZHL1
FY2023Pathogenic Exosomes in COPD1R35HL166433-01 · under RFA-HL-23-004Blalock, J EdwinUNIVERSITY OF ALABAMA AT BIRMINGHAM, ALFirst-year cost $1,026,066Study section ZHL1
FY2023Dysregulated Immunometabolism and Premature Senescence in Corticosteroid-Refractory Severe Asthma1R35HL166219-01 · under RFA-HL-23-004Ray, AnuradhaUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PAFirst-year cost $743,410Study section ZHL1
FY2023Intersection of Obesity and Heart Failure with Preserved Ejection Fraction1R35HL166565-01 · under RFA-HL-23-004Kass, David AlanJOHNS HOPKINS UNIVERSITY, MDFirst-year cost $736,477Study section ZHL1
FY2022The Centrosome as a master controller of platelet production.1R35HL161175-01 · under RFA-HL-20-011Italiano, Joseph EBOSTON CHILDREN'S HOSPITAL, MAFirst-year cost $1,062,000Study section ZHL1
FY2022Patient-specific Outcome Prediction from Cardiovascular Multimodality Imaging by Artificial Intelligence1R35HL161195-01 · under RFA-HL-20-011Slomka, Piotr JCEDARS-SINAI MEDICAL CENTER, CAFirst-year cost $1,027,005Study section ZHL1
FY2022Molecular Atlas of the Cardiac Intercalated Disc1R35HL160840-01 · under RFA-HL-20-011Delmar, MarioNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NYFirst-year cost $998,006Study section ZHL1
FY2022Mesenchymal Vascular Progenitor Depletion Promotes Lung Aging and Susceptibility to Emphysema1R35HL161238-01 · under RFA-HL-20-011Majka, Susan MNATIONAL JEWISH HEALTH, COFirst-year cost $996,000Study section ZHL1
FY2022Investigating Individual Susceptibility and Host Response in Acute Respiratory Distress Syndrome1R35HL161196-01 · under RFA-HL-20-011Meyer, Nuala JenningsUNIVERSITY OF PENNSYLVANIA, PAFirst-year cost $975,000Study section ZHL1
FY2022New and Disruptive Therapeutic Approaches to Target Fundamental Molecular Mechanisms Underlying Atrial Fibrillation1R35HL161249-01 · under RFA-HL-20-011Arora, RishiNORTHWESTERN UNIVERSITY AT CHICAGO, ILFirst-year cost $960,000Study section ZHL1
FY2022Cell competition in pulmonary fibrosis and ARDS1R35HL161169-01 · under RFA-HL-20-011De Langhe, Stijn Piet JohanMAYO CLINIC ROCHESTER, MNFirst-year cost $954,000Study section ZHL1
FY2022Connexin-based Signaling in the Heart: Cellular and Exosomal1R35HL161237-01 · under RFA-HL-20-011Gourdie, Robert GVIRGINIA POLYTECHNIC INST AND ST UNIV, VAFirst-year cost $874,987Study section ZHL1
FY2022Immune Pathophysiology of Sickle Cell Disease1R35HL161239-01 · under RFA-HL-20-011Yazdanbakhsh, KarinaNEW YORK BLOOD CENTER, NYFirst-year cost $846,806Study section ZHL1
FY2022Immunobiology of the normal and injured lung1R35HL161241-01 · under RFA-HL-20-011Looney, Mark RobertsUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CAFirst-year cost $566,011Study section ZHL1
FY2021Human and mouse transcriptome profiling identifies cross-species homology of mononuclear phagocytes1R35HL155458-01 · under RFA-HL-20-011Jakubzick, Claudia VDARTMOUTH COLLEGE, NHFirst-year cost $984,000Study section ZHL1
FY2021Novel signaling molecules regulating platelet activation1R35HL155694-01 · under RFA-HL-20-011Kunapuli, Satya P.TEMPLE UNIV OF THE COMMONWEALTH, PAFirst-year cost $950,997Study section ZHL1
FY2021Neurobiology of the Bronchopulmonary System1R35HL155671-01 · under RFA-HL-20-011Undem, Bradley JoelJOHNS HOPKINS UNIVERSITY, MDFirst-year cost $938,076Study section ZHL1
FY2021Insights into the molecular mechanisms regulating vascular and immune metabolism in vascular diseases1R35HL155988-01 · under RFA-HL-20-011Suarez, YajairaYALE UNIVERSITY, CTFirst-year cost $936,044Study section ZHL1
FY2021Endogenous circadian mechanisms underlying cardiovascular risk1R35HL155681-01 · under RFA-HL-20-011Shea, Steven AOREGON HEALTH & SCIENCE UNIVERSITY, ORFirst-year cost $924,000Study section ZHL1
FY2021Understanding the Cardiac Benefits of Exercise at the Cellular and Molecular Level1R35HL155318-01 · under RFA-HL-20-011Rosenzweig, AnthonyMASSACHUSETTS GENERAL HOSPITAL, MAFirst-year cost $909,471Study section ZHL1
FY2021Tissue factor-dependent coagulation in thrombosis and immune responses1R35HL155657-01 · under RFA-HL-20-011Mackman, NigelUNIV OF NORTH CAROLINA CHAPEL HILL, NCFirst-year cost $863,736Study section ZHL1
FY2021TRP channels as fundamental sensors of the cerebral microcirculation1R35HL155008-01 · under RFA-HL-20-011Earley, ScottUNIVERSITY OF NEVADA RENO, NVFirst-year cost $862,070Study section ZHL1
FY2021Transendothelial Migration of Leukocytes: Developing New Paradigms in Health and Disease1R35HL155652-01 · under RFA-HL-20-011Muller, William ANORTHWESTERN UNIVERSITY AT CHICAGO, ILFirst-year cost $848,469Study section ZHL1
FY2021Mechanisms addressing the causal relationships of sleep, circadian rhythms, and cardiometabolic health1R35HL155670-01 · under RFA-HL-20-011St-Onge, Marie-PierreCOLUMBIA UNIVERSITY HEALTH SCIENCES, NYFirst-year cost $815,838Study section ZHL1
FY2021Determinants of Aorta Heterogeneity1R35HL155649-01 · under RFA-HL-20-011Daugherty, AlanUNIVERSITY OF KENTUCKY, KYFirst-year cost $596,149Study section ZHL1
FY2021Role of mitophagy in age-related respiratory and vascular diseases1R35HL155169-01 · under RFA-HL-20-011Goldstein, Daniel RobertUNIVERSITY OF MICHIGAN AT ANN ARBOR, MIFirst-year cost $585,000Study section ZHL1
FY2020New Mechanistic Insights & Therapeutic Applications of Megakaryocytes/Platelets1R35HL150698-01 · under RFA-HL-20-011Poncz, MortimerCHILDREN'S HOSP OF PHILADELPHIA, PAFirst-year cost $1,056,000Study section ZHL1
FY2020Identifying new strategies for prevention of cardiovascular complications of diabetes1R35HL150754-01 · under RFA-HL-20-011Bornfeldt, Karin E.UNIVERSITY OF WASHINGTON, WAFirst-year cost $1,037,755Study section ZHL1
FY2020Adaptable tissue-specific endothelial cells for organ regeneration1R35HL150809-01 · under RFA-HL-20-011Rafii, ShahinWEILL MEDICAL COLL OF CORNELL UNIV, NYFirst-year cost $1,032,314Study section ZHL1
FY2020Novel vascular smooth muscle cell progenitors in development and disease1R35HL150766-01 · under RFA-HL-20-011Greif, DanielYALE UNIVERSITY, CTFirst-year cost $1,003,144Study section ZHL1
FY2020Platelet Exocytosis and Endocytosis in Thrombosis and Immunity1R35HL150818-01 · under RFA-HL-20-011Whiteheart, Sidney WaldoUNIVERSITY OF KENTUCKY, KYFirst-year cost $970,913Study section ZHL1
FY2020Program to promote lung regeneration and block fibrosis1R35HL150767-01 · under RFA-HL-20-011Chapman, Harold AUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CAFirst-year cost $965,500Study section ZHL1
FY2020Leveraging zebrafish models to dissect and enhance heart regeneration1R35HL150713-01 · under RFA-HL-20-011Poss, Kenneth DDUKE UNIVERSITY, NCFirst-year cost $960,647Study section ZHL1
FY2020Mechanisms of integrin signaling and a new anti-platelet/anti-inflammatory approach1R35HL150797-01 · under RFA-HL-20-011Du, XiaopingUNIVERSITY OF ILLINOIS AT CHICAGO, ILFirst-year cost $959,400Study section ZHL1
FY2020Ca2+ Signaling Networks in Health and Disease1R35HL150778-01 · under RFA-HL-20-011Trebak, MohamedPENNSYLVANIA STATE UNIV HERSHEY MED CTR, PAFirst-year cost $944,709Study section ZHL1
FY2020Vascular Barrier Leakage in Inflammation1R35HL150732-01 · under RFA-HL-20-011Yuan, Sarah YUNIVERSITY OF SOUTH FLORIDA, FLFirst-year cost $893,838Study section ZHL1
FY2020Cell-cell interactions governing lung epithelial progenitor cells1R35HL150876-01 · under RFA-HL-20-011Kim, Carla F.BOSTON CHILDREN'S HOSPITAL, MAFirst-year cost $885,000Study section ZHL1
FY2020Molecular Regulation of Progressive Pulmonary Fibrosis1R35HL150829-01 · under RFA-HL-20-011Noble, Paul WesleyCEDARS-SINAI MEDICAL CENTER, CAFirst-year cost $847,538Study section ZHL1
FY2020Viral and allergen-driven immunity in chronic lung disease1R35HL150682-01 · under RFA-HL-20-011Lukacs, Nicholas WUNIVERSITY OF MICHIGAN AT ANN ARBOR, MIFirst-year cost $684,921Study section ZHL1
FY2019Molecular and Translational Studies in Hematologic Disorders1R35HL145262-01 · under RFA-HL-16-024Lopez, Jose AronBLOODWORKS, WAFirst-year cost $1,105,665Study section ZHL1
FY2019Toward a Mechanism-Based Approach to Treating Cardiac Arrhythmia1R35HL144980-01 · under RFA-HL-16-024Knollmann, Bjorn CVANDERBILT UNIVERSITY MEDICAL CENTER, TNFirst-year cost $1,020,000Study section ZHL1
FY2019Airway epithelial cell gene regulation: new mechanisms and therapeutic strategies1R35HL145235-01 · under RFA-HL-16-024Erle, David JUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CAFirst-year cost $961,617Study section ZHL1
FY2019A Mechanistic and Translational Research Program Linking Impaired Resolution, Defective Efferocytosis, and Clonal Hematopoiesis to the Formation of Clinically Dangerous Atherosclerotic Plaques1R35HL145228-01 · under RFA-HL-16-024Tabas, Ira ACOLUMBIA UNIVERSITY HEALTH SCIENCES, NYFirst-year cost $955,996Study section ZHL1
FY2019Defining and Controlling Airway Disease1R35HL145242-01 · under RFA-HL-16-024Holtzman, Michael JWASHINGTON UNIVERSITY, MOFirst-year cost $939,000Study section ZHL1
FY2019Novel Functions of Lung Macrophages and Fibroblasts in Pulmonary Inflammation and Fibrosis1R35HL144979-01 · under RFA-HL-16-024Peters-Golden, Marc LUNIVERSITY OF MICHIGAN AT ANN ARBOR, MIFirst-year cost $928,378Study section ZHL1
FY2019Vascular macrophages and T cells in atherosclerosis1R35HL145241-01 · under RFA-HL-16-024Ley, Klaus F.LA JOLLA INSTITUTE FOR IMMUNOLOGY, CAFirst-year cost $927,585Study section ZHL1
FY2019PPARG-dependent Mechanisms Control Endothelial-Smooth Muscle Coordination, Arterial Pressure, Vasomotor Function and Arterial Stiffness1R35HL144807-01 · under RFA-HL-16-024Sigmund, Curt DanielMEDICAL COLLEGE OF WISCONSIN, WIFirst-year cost $924,000Study section ZHL1
FY2019Organizational strategies for improving evidence-uptake in intensive care1R35HL144804-01 · under RFA-HL-16-024Kahn, Jeremy MUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PAFirst-year cost $922,387Study section ZHL1
FY2019Capillaries as a Sensory Web that Controls Cerebral Blood Flow in Health and Disease1R35HL140027-01 · under RFA-HL-16-024Nelson, Mark TUNIVERSITY OF VERMONT & ST AGRIC COLLEGE, VTFirst-year cost $919,963Study section ZHL1
FY2019Role of the giant protein titin in cardiac health and disease1R35HL144998-01 · under RFA-HL-16-024Granzier, Henk L.UNIVERSITY OF ARIZONA, AZFirst-year cost $884,369Study section ZHL1
FY2019Renewing the heart: cardiomyocyte cell cycle regulation1R35HL144984-01 · under RFA-HL-16-024Evans, Sylvia MUNIVERSITY OF CALIFORNIA, SAN DIEGO, CAFirst-year cost $865,334Study section ZHL1
FY2019Immunobiology of Lung Injury and Fibrosis1R35HL144481-01 · under RFA-HL-16-024Moore, Bethany B.UNIVERSITY OF MICHIGAN AT ANN ARBOR, MIFirst-year cost $847,613Study section ZHL1
FY2019Cilia in Heart Development and Disease1R35HL145249-01 · under RFA-HL-16-024Brueckner, MartinaYALE UNIVERSITY, CTFirst-year cost $726,127Study section ZHL1
FY2019Small GTPases in the biology of platelets and megakaryocytes1R35HL144976-01 · under RFA-HL-16-024Bergmeier, WolfgangUNIV OF NORTH CAROLINA CHAPEL HILL, NCFirst-year cost $561,180Study section ZHL1
FY2019Translational Control of Megakaryocyte and Platelet Gene Expression in Disease1R35HL145237-01 · under RFA-HL-16-024Weyrich, Andrew SUNIVERSITY OF UTAH, UTFirst-year cost $253,797Study section ZHL1
FY2018Insights into the Molecular and Cellular Mechanisms governing Endothelial Function1R35HL139945-01 · under RFA-HL-16-024Sessa, William CYALE UNIVERSITY, CTFirst-year cost $1,005,000Study section ZHL1
FY2018Embryonic origins of endothelial heterogeneity1R35HL140017-01 · under RFA-HL-16-024Lawson, Nathan DUNIV OF MASSACHUSETTS MED SCH WORCESTER, MAFirst-year cost $1,005,000Study section ZHL1
FY2018Imaging organ system interfaces in ischemic heart disease1R35HL139598-01 · under RFA-HL-16-024Nahrendorf, MatthiasMASSACHUSETTS GENERAL HOSPITAL, MAFirst-year cost $987,881Study section ZHL1
FY2018Basic Investigation and Translational Applications Concerning the Cell and Molecular Biology of Blood and Vascular Cells1R35HL139937-01 · under RFA-HL-16-024Newman, Peter JVERSITI WISCONSIN, INC., WIFirst-year cost $986,967Study section ZHL1
FY2018Cardiac lineage determination and nuclear architecture1R35HL140018-01 · under RFA-HL-16-024Epstein, Jonathan A.UNIVERSITY OF PENNSYLVANIA, PAFirst-year cost $957,952Study section ZHL1
FY2018CaMKII signaling in physiology, heart failure and arrhythmias1R35HL140034-01 · under RFA-HL-16-024Anderson, Mark EJOHNS HOPKINS UNIVERSITY, MDFirst-year cost $950,658Study section ZHL1
FY2018Tie2-driven vascular control in critical illness1R35HL139424-01 · under RFA-HL-16-024Parikh, Samir MBETH ISRAEL DEACONESS MEDICAL CENTER, MAFirst-year cost $939,488Study section ZHL1
FY2018Mechanisms of vascular and valvular calcification1R35HL139602-01 · under RFA-HL-16-024Giachelli, Cecilia MUNIVERSITY OF WASHINGTON, WAFirst-year cost $931,250Study section ZHL1
FY2018Eating, Activity, and Weight-Related Problems Across the Life Course in Diverse Populations1R35HL139853-01 · under RFA-HL-16-024Neumark-Sztainer, Dianne RUNIVERSITY OF MINNESOTA, MNFirst-year cost $927,214Study section ZHL1
FY2018Vascular Growth and Regeneration1R35HL140014-01 · under RFA-HL-16-024Iruela-Arispe, M. LuisaUNIVERSITY OF CALIFORNIA LOS ANGELES, CAFirst-year cost $924,642Study section ZHL1
FY2018MOLECULAR AND CELLULAR CONTROL OF ANGIOGENESIS1R35HL139950-01 · under RFA-HL-16-024Bautch, Victoria LUNIV OF NORTH CAROLINA CHAPEL HILL, NCFirst-year cost $922,296Study section ZHL1
FY2018Potassium Channels and Control of Cardiovascular Function1R35HL140024-01 · under RFA-HL-16-024Nichols, Colin GWASHINGTON UNIVERSITY, MOFirst-year cost $915,000Study section ZHL1
FY2018CD4_T-cell_Immunity_in_the_Lung1R35HL139930-01 · under RFA-HL-16-024Kolls, Jay KTULANE UNIVERSITY OF LOUISIANA, LAFirst-year cost $860,539Study section ZHL1
FY2018Variant Hemoglobin and Cardiorespiratory Regulation in Humans1R35HL139854-01 · under RFA-HL-16-024Joyner, Michael JMAYO CLINIC ROCHESTER, MNFirst-year cost $806,184Study section ZHL1
FY2018Biochemistry and Pathophysiology of Factor XI and Contact Activation1R35HL140025-01 · under RFA-HL-16-024Gailani, DavidVANDERBILT UNIVERSITY MEDICAL CENTER, TNFirst-year cost $790,000Study section ZHL1
FY2018Genomics of Pulmonary Vascular Disease1R35HL140019-01 · under RFA-HL-16-024Aldred, Micheala AINDIANA UNIVERSITY INDIANAPOLIS, INFirst-year cost $777,434Study section ZHL1
FY2018Investigating Mechanisms for Lipid Transport in Health and Disease1R35HL139725-01 · under RFA-HL-16-024Young, Stephen G.UNIVERSITY OF CALIFORNIA LOS ANGELES, CAFirst-year cost $775,320Study section ZHL1
FY2018Deconvoluting the Vascular Adhesome1R35HL139947-01 · under RFA-HL-16-024Ginsberg, Mark HowardUNIVERSITY OF CALIFORNIA, SAN DIEGO, CAFirst-year cost $774,183Study section ZHL1
FY2018Controlling Influences of Oxygen Tension and CD26/DPP4 Enzymatic Activity on Regulation of Hematopoietic Stem/Progenitor Cells and Hematopoiesis During Health, Ageing, and Disease1R35HL139599-01 · under RFA-HL-16-024Broxmeyer, Hal E.INDIANA UNIVERSITY INDIANAPOLIS, INFirst-year cost $768,104Study section ZHL1
FY2018Mechanisms of Immune Activation in Hypertension1R35HL140016-01 · under RFA-HL-16-024Harrison, David GVANDERBILT UNIVERSITY MEDICAL CENTER, TNFirst-year cost $767,077Study section ZHL1
FY2018Molecular mechanism and targeting of chronic pain in sickle cell disease1R35HL140031-01 · under RFA-HL-16-024Wang, Zaijie JimUNIVERSITY OF ILLINOIS AT CHICAGO, ILFirst-year cost $661,398Study section ZHL1
FY2018SOD3 regulation of redox sensitive signaling in pulmonary vascular diseases1R35HL139726-01 · under RFA-HL-16-024Nozik, Eva S.UNIVERSITY OF COLORADO DENVER, COFirst-year cost $571,435Study section ZHL1
FY2017Phenotypic and Molecular Signatures for Sleep Apnea and Related Morbidities1R35HL135818-01 · under RFA-HL-16-024Redline, Susan S.BRIGHAM AND WOMEN'S HOSPITAL, MAFirst-year cost $1,057,510Study section ZHL1
FY2017The Identification and characterization of genetic variants underlying cardiovascular diseases1R35HL135767-01 · under RFA-HL-16-024Mani, AryaYALE UNIVERSITY, CTFirst-year cost $1,005,000Study section ZHL1
FY2017Leveraging Protein Kinase G-1 Nanodomain Control and Molecular Targeting to Enhance its Therapeutic Use Against Myocardial Disease1R35HL135827-01 · under RFA-HL-16-024Kass, David AlanJOHNS HOPKINS UNIVERSITY, MDFirst-year cost $994,861Study section ZHL1
FY2017Beyond the barrier: alveolar epithelial cell biology in health and disease1R35HL135747-01 · under RFA-HL-16-024Borok, ZeaUNIVERSITY OF SOUTHERN CALIFORNIA, CAFirst-year cost $990,000Study section ZHL1
FY2017Phenotyping Genetic Disorders of Hepatic Lipid and Lipoprotein Metabolism in Cells, Mice, and Men1R35HL135833-01 · under RFA-HL-16-024Ginsberg, Henry NCOLUMBIA UNIVERSITY HEALTH SCIENCES, NYFirst-year cost $953,882Study section ZHL1
FY2017KLF control of aging and age-associated cardiovascular disease1R35HL135789-01 · under RFA-HL-16-024Jain, Mukesh KumarCASE WESTERN RESERVE UNIVERSITY, OHFirst-year cost $951,000Study section ZHL1
FY2017Mechanisms Controlling Expansion and Lineage Specification of Airway Progenitors in Development and Disease1R35HL135834-01 · under RFA-HL-16-024Cardoso, Wellington V.COLUMBIA UNIVERSITY HEALTH SCIENCES, NYFirst-year cost $948,730Study section ZHL1
FY2017AIBP therapy1R35HL135737-01 · under RFA-HL-16-024Miller, YuryUNIVERSITY OF CALIFORNIA, SAN DIEGO, CAFirst-year cost $930,000Study section ZHL1
FY2017Mechanisms of sphingolipid signaling in vascular health and disease1R35HL135821-01 · under RFA-HL-16-024Hla, Timothy TunBOSTON CHILDREN'S HOSPITAL, MAFirst-year cost $926,656Study section ZHL1
FY2017S-glutathionylation chemistry in fibrotic lung remodeling1R35HL135828-01 · under RFA-HL-16-024Janssen-Heininger, Yvonne M. W.UNIVERSITY OF VERMONT & ST AGRIC COLLEGE, VTFirst-year cost $923,815Study section ZHL1
FY2017THE MITOCHONDRIAL DYNAMISM/FITNESS/BIOGENESIS INTERACTOME IN CARDIAC DISEASE1R35HL135736-01 · under RFA-HL-16-024Dorn, Gerald W.WASHINGTON UNIVERSITY, MOFirst-year cost $915,000Study section ZHL1
FY2017Signaling mechanisms and functions related to patho-physiology of vascular, lung and blood systems1R35HL135805-01 · under RFA-HL-16-024Wu, DianqingYALE UNIVERSITY, CTFirst-year cost $912,314Study section ZHL1
FY2017Omics Phenotyping for Identifying Molecular Signatures of the Healthy and Failing Heart: An Integrated Data Science Platform1R35HL135772-01 · under RFA-HL-16-024Ping, PeipeiUNIVERSITY OF CALIFORNIA LOS ANGELES, CAFirst-year cost $910,734Study section ZHL1
FY2017Defining novel mechanisms for human arrhythmia1R35HL135754-01 · under RFA-HL-16-024Mohler, Peter J.OHIO STATE UNIVERSITY, OHFirst-year cost $908,050Study section ZHL1
FY2017How inflammation and thrombosis fuel disease and aging: Focus on NETs1R35HL135765-01 · under RFA-HL-16-024Wagner, Denisa DBOSTON CHILDREN'S HOSPITAL, MAFirst-year cost $885,000Study section ZHL1
FY2017A Novel Exosomal Inflammatory Pathway1R35HL135710-01 · under RFA-HL-16-024Blalock, J EdwinUNIVERSITY OF ALABAMA AT BIRMINGHAM, ALFirst-year cost $877,566Study section ZHL1
FY2017Pneumonia Biology1R35HL135756-01 · under RFA-HL-16-024Mizgerd, Joseph PBOSTON UNIVERSITY MEDICAL CAMPUS, MAFirst-year cost $868,938Study section ZHL1
FY2017Pediatric Heart Disease: Getting from Mutations to Therapeutics1R35HL135742-01 · under RFA-HL-16-024Gelb, Bruce DICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NYFirst-year cost $856,106Study section ZHL1
FY2017Non-coding RNA regulation of cholesterol homeostasis and atherosclerosis1R35HL135799-01 · under RFA-HL-16-024Moore, Kathryn JNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NYFirst-year cost $823,175Study section ZHL1
FY2017Emergency Myelopoiesis Pathways in the Control of Blood Production1R35HL135763-01 · under RFA-HL-16-024Passegue, EmmanuelleCOLUMBIA UNIVERSITY HEALTH SCIENCES, NYFirst-year cost $816,806Study section ZHL1
FY2017A Gata456 Pipeline of Discovery1R35HL135778-01 · under RFA-HL-16-024Evans, Todd RWEILL MEDICAL COLL OF CORNELL UNIV, NYFirst-year cost $810,723Study section ZHL1
FY2017Innate Immune Clearance of Host-Adapted Pulmonary Pathogens1R35HL135800-01 · under RFA-HL-16-024Prince, Alice SCOLUMBIA UNIVERSITY HEALTH SCIENCES, NYFirst-year cost $796,640Study section ZHL1
FY2017Neural control of breathing1R35HL135779-01 · under RFA-HL-16-024Feldman, Jack LUNIVERSITY OF CALIFORNIA LOS ANGELES, CAFirst-year cost $781,655Study section ZHL1
FY2017Role of LDL receptor family members in protecting the vasculature1R35HL135743-01 · under RFA-HL-16-024Strickland, Dudley K.UNIVERSITY OF MARYLAND BALTIMORE, MDFirst-year cost $770,872Study section ZHL1
FY2017Ion Channels and Membrane Receptors in Pulmonary Arterial Hypertension1R35HL135807-01 · under RFA-HL-16-024Yuan, Jason X JUNIVERSITY OF ARIZONA, AZFirst-year cost $767,500Study section ZHL1
FY2017The Molecular Genetics of Hemostasis1R35HL135793-01 · under RFA-HL-16-024Ginsburg, DavidUNIVERSITY OF MICHIGAN AT ANN ARBOR, MIFirst-year cost $578,742Study section ZHL1
FY2017Thiol Isomerases in Hemostasis and Thrombosis1R35HL135775-01 · under RFA-HL-16-024Flaumenhaft, Robert CBETH ISRAEL DEACONESS MEDICAL CENTER, MAFirst-year cost $432,500Study section ZHL1
FY2017Macrophages in homeostasis and cardiovascular disease1R35HL135752-01 · under RFA-HL-16-024Swirski, Filip KMASSACHUSETTS GENERAL HOSPITAL, MAFirst-year cost $427,500Study section ZHL1
FY2017Structure-Function and Roles of Protease-Activated Receptors1R35HL135755-01 · under RFA-HL-16-024Coughlin, Shaun R.UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CAFirst-year cost $396,250Study section ZHL1
FY2017Therapeutic Implications of Molecular Defects in Bone Marrow Failure1R35HL135795-01 · under RFA-HL-16-024Maciejewski, Jaroslaw P.CLEVELAND CLINIC LERNER COM-CWRU, OHFirst-year cost $396,250Study section ZHL1
FY2017Mechanisms in Blood Clotting1R35HL135823-01 · under RFA-HL-16-024Morrissey, James H.UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, ILFirst-year cost $311,265Study section ZHL1
Newest fiscal year first, then first-year cost.

Patents from its funded projects

21 patents name 15 of the 155 funded projects. The newest 5, by patent number.

  1. US 12,725,261 (opens the patent at USPTO, a PDF, in a new tab)CONVOLUTIONAL LONG SHORT-TERM MEMORY NETWORKS FOR RAPID MEDICAL IMAGE SEGMENTATIONGranted September 1, 2026 to CEDARS-SINAI MEDICAL CENTERR35HL161195 · CEDARS-SINAI MEDICAL CENTER, CA
  2. US 12,714,678 (opens the patent at USPTO, a PDF, in a new tab)PEPTIDES AND METHODS OF TREATING SEPSIS, ATHEROSCLEROSIS, THROMBOSIS, STROKE, HEART ATTACK AND INFLAMMATIONGranted August 25, 2026 to The Board of Trustees of the University of IllinoisR35HL150797 · UNIVERSITY OF ILLINOIS AT CHICAGO, IL
  3. US 12,678,433 (opens the patent at USPTO, a PDF, in a new tab)COMPOUNDS FOR TREATMENT OF HEMOLYSIS-AND INFLAMMASOME-ASSOCIATED DISEASESGranted July 14, 2026 to New York Blood Center, Inc.R35HL161239 · NEW YORK BLOOD CENTER, NY
  4. US 12,661,390 (opens the patent at USPTO, a PDF, in a new tab)ADAMTS13 TREATMENT TO ENHANCE GRAFT SURVIVALGranted June 23, 2026 to THE CHILDREN'S MEDICAL CENTER CORPORATIONR35HL135765 · BOSTON CHILDREN'S HOSPITAL, MA
  5. US 12,583,920 (opens the patent at USPTO, a PDF, in a new tab)COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF ALZHEIMER'S DISEASEGranted March 24, 2026 to UNIVERSITY OF MARYLAND, BALTIMORE and THE GENERAL HOSPITAL CORPORATIONR35HL135743 · UNIVERSITY OF MARYLAND BALTIMORE, MD

Each number opens the patent at USPTO, beside the project NIH ties it to and that project's institution. NIH ties a patent to a project, not to a year of its funding, and says its list is incomplete. The grant date and the owners are USPTO's: the organizations the patent names as assignees on the day it was granted. Source: United States Patent and Trademark Office, www.uspto.gov, which does not endorse ScienceDex.

Data: Grants.gov's daily extract and NIH's notice pages, award files and patents file, in ScienceGraph release conductgrants-2026-11-13-0.3.2. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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RFA-HL-26-002: NHLBI Outstanding Investigator Award (OIA) (R35 Clinical Trial Optional) | ScienceDex | ConductScience