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NIH funding notice RFA-MH-16-775

BRAIN Initiative: Development and Validation of Novel Tools to Analyze Cell-Specific and Circuit-Specific Processes in the Brain (R01)

Closed on February 2, 2016.

Posted
November 17, 2015
Close date
February 2, 2016
Activity codes
R01
Institutes taking part
NIMH, NEI, NIA, NIAAA, NIBIB, NICHD, NIDCD, NIDA, NINDS, NCCIH

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: RFA-MH-15-225 BRAIN Initiative: Development and Validation of Novel Tools to Analyze Cell-Specific and Circuit Specific Processes in the Brain (U01)
  2. 2 steps back: RFA-MH-14-216 BRAIN Initiative: Development and Validation of Novel Tools to Analyze Cell-Specific and Circuit Specific Processes in the Brain (U01)

Replaced by RFA-MH-17-220.

Who won it before

34 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $26,336,067 in first-year total cost, median $716,835.

Most frequent study sections

  1. Special Emphasis Panel[ZMH1 ERB-L (04)]19
  2. Special Emphasis Panel[ZMH1 ERB-L (06)]15

Most frequent institutions

  1. MASSACHUSETTS INSTITUTE OF TECHNOLOGY4
  2. COLD SPRING HARBOR LABORATORY2
  3. JOHNS HOPKINS UNIVERSITY2
  4. WASHINGTON UNIVERSITY2
  5. BOSTON CHILDREN'S HOSPITAL1
Competing awards under RFA-MH-16-775 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2016In situ transcriptional analysis of brain circuits at single cell resolution1R01MH111502-01DULAC, CATHERINEREGEV, AVIVZHUANG, XIAOWEIHARVARD UNIVERSITY, MA$1,593,922ZMH1
2016Mapping and controlling gene expression in inhibitory interneurons mammals1R01MH111529-01FISHELL, GORDON JNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$1,124,687ZMH1
2016Next-gen Opto-GPCRs: spatiotemporal simulation of neuromodulator signaling1R01MH111520-01BRUCHAS, MICHAEL R.SUNAHARA, ROGER KWASHINGTON UNIVERSITY, MO$1,103,836ZMH1
2016Developing a noninvasive method to manipulate specific cell types within the mammalian brain1R01MH111534-01CHALASANI, SREEKANTH H.SALK INSTITUTE FOR BIOLOGICAL STUDIES, CA$1,035,349ZMH1
2016Realization of Optical Cell-based Reporters for in vivo Detection of Neuropeptides1R01MH111499-01KLEINFELD, DAVIDSLESINGER, PAUL AICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$996,914ZMH1
2016A platform for high-throughput production of targeting systems for cell-type-specific transgene expression in wild-type animals1R01MH111503-01WICKERSHAM, IAN RMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$993,992ZMH1
2016Multiparametric Biosensor Imaging in Brain Slices1R01MH111527-01BLANPIED, THOMAS AMEREDITH, ANDREA LRIZZO, MEGAN AUNIVERSITY OF MARYLAND BALTIMORE, MD$635,832ZMH1
2016Multiplex in vivo imaging of cell-specific and circuit-specific signaling pathways during synaptic plasticity1R01MH111516-01HUGANIR, RICHARD LZHANG, JINJOHNS HOPKINS UNIVERSITY, MD$619,950ZMH1
2016Optogenetic signaling inhibitors for studying brain plasticity1R01MH111486-01GAN, WENBIAOYASUDA, RYOHEIMAX PLANCK FLORIDA CORPORATION, FL$482,250ZMH1
2015AN INDUCIBLE MOLECULAR MEMORY SYSTEM TO RECORD TRANSIENT STATES OF CNS CELLS1U01MH109133-01 · under RFA-MH-15-225MITRA, ROBI DWASHINGTON UNIVERSITY, MO$1,146,862ZMH1
2015Intrabody-dependent activation of cell-specific gene expression in CNS1U01MH109102-01 · under RFA-MH-15-225BLACKSHAW, SETHJOHNS HOPKINS UNIVERSITY, MD$1,048,356ZMH1
2015SYNPLA: A scaleable method for monitoring circuit-specific learning-induced changes in synaptic strength1U01MH109113-01 · under RFA-MH-15-225MALINOW, ROBERTOZADOR, ANTHONY MCOLD SPRING HARBOR LABORATORY, NY$1,005,931ZMH1
2015Tracing Brain Circuits by Transneuronal Control of Transcription1U01MH109147-01 · under RFA-MH-15-225HONG, ELIZABETH JENNIFERLOIS, CARLOSZINN, KAI GCALIFORNIA INSTITUTE OF TECHNOLOGY, CA$936,185ZMH1
2015Anion channelrhodopsin-based viral tools to manipulate brain networks in behaving animals1U01MH109146-01 · under RFA-MH-15-225DRAGOI, VALENTINJANZ, ROGERSPUDICH, JOHN LEEUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$931,074ZMH1
2015BRAIN Initiative: Integrated Multimodal Analysis of Cell and Circuit-Specific Processes in Hippocampal Function1U01MH109062-01 · under RFA-MH-15-225SWEEDLER, JONATHAN V.UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$778,402ZMH1
2015A new strategy for cell-type specific gene disruption in flies and mice1U01MH109119-01 · under RFA-MH-15-225CLANDININ, THOMAS ROBERTSHAH, NIRAO MAHESHSTANFORD UNIVERSITY, CA$750,263ZMH1
2015Anterograde monosynaptic tracing1U01MH109129-01 · under RFA-MH-15-225WICKERSHAM, IAN RMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$728,000ZMH1
2015Novel tools for cell-specific imaging of functional connectivity and circuit operations1U01MH109069-01 · under RFA-MH-15-225ISACOFF, EHUDUNIVERSITY OF CALIFORNIA BERKELEY, CA$705,670ZMH1
2015Generating Multiple Circuit and Neuron Type Specific AAV Vectors With Cross-Species Applicability1U01MH109107-01 · under RFA-MH-15-225HE, ZHIGANGBOSTON CHILDREN'S HOSPITAL, MA$700,563ZMH1
2015Sub-micrometer x-ray tomography for neuroanatomy1U01MH109100-01 · under RFA-MH-15-225JACOBSEN, CHRIS JOHNSONKORDING, KONRAD P.NORTHWESTERN UNIVERSITY, IL$677,177ZMH1
2015Sparse, Strong and Large Area Targeting of Genetically Encoded Indicators1U01MH109091-01 · under RFA-MH-15-225ANTIC, SRDJAN DKNOPFEL, THOMASUNIVERSITY OF CONNECTICUT SCH OF MED/DNT, CT$549,797ZMH1
2015LIPS: A novel technology for spatial and temporal control of protein synthesis in dendritic spines1U01MH109087-01 · under RFA-MH-15-225GAN, WENBIAOJAFFREY, SAMIE RWEILL MEDICAL COLL OF CORNELL UNIV, NY$525,875ZMH1
2015Genetic tools and imaging technology for mapping cholinergic engrams of anxiety1U01MH109104-01 · under RFA-MH-15-225ROLE, LORNA WSTATE UNIVERSITY NEW YORK STONY BROOK, NY$479,913ZMH1
2015Engineered viral tropism for cell-type specific manipulation of neuronal circuits1U01MH109038-01 · under RFA-MH-15-225SCHMIDT, DANIELTHOMAS, MARK JOHNUNIVERSITY OF MINNESOTA, MN$357,250ZMH1
2014DREADD2.0: AN ENHANCED CHEMOGENETIC TOOLKIT1U01MH105892-01 · under RFA-MH-14-216JIN, JIANKASH, THOMAS L.ROTH, BRYAN L.UNIV OF NORTH CAROLINA CHAPEL HILL, NC$997,398ZMH1
2014Mapping neuronal chloride microdomains1U01MH106013-01 · under RFA-MH-14-216STALEY, KEVIN J.MASSACHUSETTS GENERAL HOSPITAL, MA$913,294ZMH1
2014Ultra-Multiplexed Nanoscale In Situ Proteomics for Understanding Synapse Types1U01MH106011-01 · under RFA-MH-14-216BATHE, MARKBOYDEN, EDWARD S.YIN, PENGMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$735,278ZMH1
2014Novel technologies for nontoxic transsynaptic tracing1U01MH106018-01 · under RFA-MH-14-216WICKERSHAM, IAN RMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$699,916ZMH1
2014Developing drivers for neuron type-specific gene expression1U01MH105924-01 · under RFA-MH-14-216HOBERT, OLIVERCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$626,021ZMH1
2014Novel Genetic Strategy for Sparse Labeling and Manipulation of Mammalian Neurons1U01MH106008-01 · under RFA-MH-14-216YANG, XIANGDONG WILLIAMUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$592,089ZMH1
2014In-vivo circuit activity measurement at single cell, sub-threshold resolution1U01MH106027-01 · under RFA-MH-14-216FOREST, CRAIGSTANLEY, GARRETT B.GEORGIA INSTITUTE OF TECHNOLOGY, GA$504,959ZMH1
2014Identification of enhancers whose activity defines cortical interneuron types1U01MH105948-01 · under RFA-MH-14-216RUBENSTEIN, JOHN L. R.SOHAL, VIKAAS SINGHUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$487,159ZMH1
2014An optogenetic toolkit for the interrogation and control of single cells.1U01MH106035-01 · under RFA-MH-14-216HANNON, GREGORY JCOLD SPRING HARBOR LABORATORY, NY$452,400ZMH1
2014Remote regulation of neural activity1U01MH105941-01 · under RFA-MH-14-216STANLEY, SARAH AMYROCKEFELLER UNIVERSITY, NY$419,503ZMH1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-10-0.1.1. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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