The notices it replaced
- Reissues: RFA-MH-16-775 BRAIN Initiative: Development and Validation of Novel Tools to Analyze Cell-Specific and Circuit-Specific Processes in the Brain (R01)
- 2 steps back: RFA-MH-15-225 BRAIN Initiative: Development and Validation of Novel Tools to Analyze Cell-Specific and Circuit Specific Processes in the Brain (U01)
- 3 steps back: RFA-MH-14-216 BRAIN Initiative: Development and Validation of Novel Tools to Analyze Cell-Specific and Circuit Specific Processes in the Brain (U01)
Replaced by RFA-MH-19-136.
Who won it before
51 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $67,958,368 in first-year total cost, median $996,914.
Most frequent study sections
- Special Emphasis Panel[ZMH1 ERB-L (04)]19
- Special Emphasis Panel[ZMH1 ERB-L (06)]15
- Special Emphasis Panel[ZMH1 ERB-M (03)]11
- Special Emphasis Panel[ZMH1 ERB-C (03)]6
Most frequent institutions
- MASSACHUSETTS INSTITUTE OF TECHNOLOGY4
- COLD SPRING HARBOR LABORATORY3
- WASHINGTON UNIVERSITY3
- ALLEN INSTITUTE2
- CALIFORNIA INSTITUTE OF TECHNOLOGY2
| FY | Project | PIs | Institution | First-year cost | Study section |
|---|---|---|---|---|---|
| 2018 | DART2.0: comprehensive cell type-specific behavioral neuropharmacology1RF1MH117055-01 | TADROSS, MICHAEL R | DUKE UNIVERSITY, NC | $3,838,425 | ZMH1 |
| 2018 | PARALLEL ANALYSIS OF TRANSCRIPTION AND PROTEIN-DNA INTERACTIONS IN SINGLE CNS CELLS1RF1MH117070-01 | DOUGHERTY, JOSEPH DMITRA, ROBI D | WASHINGTON UNIVERSITY, MO | $3,148,838 | ZMH1 |
| 2018 | Technology for functional study of cells and circuits in large postmortem brains ex vivo1RF1MH117064-01 | SESTAN, NENAD | YALE UNIVERSITY, CT | $2,801,084 | ZMH1 |
| 2018 | Noninvasive Gene Delivery for Monitoring and Perturbing Cell Types and Circuits in Transgenic and Non-Transgenic Animals1RF1MH117069-01 | GRADINARU, VIVIANA | CALIFORNIA INSTITUTE OF TECHNOLOGY, CA | $2,301,120 | ZMH1 |
| 2018 | A method for anterograde trans-synaptic tracing1RF1MH116989-01 | ARNOLD, DONALD B | UNIVERSITY OF SOUTHERN CALIFORNIA, CA | $1,706,735 | ZMH1 |
| 2018 | Brain-wide correlation of single-cell firing properties to patterns of gene expression1RF1MH117042-01 | COHEN, ADAM EZRA | HARVARD UNIVERSITY, MA | $1,203,825 | ZMH1 |
| 2017 | Development of tools for cell-type specific labeling of human and mouse neocortical neurons1RF1MH114126-01 | LEIN, EDLEVI, BOAZ PIRIETING, JONATHAN T | ALLEN INSTITUTE, WA | $4,479,935 | ZMH1 |
| 2017 | Integrative approach to classifying neuronal cell types of the mouse hippocampus1RF1MH114112-01 | DONG, HONG-WEIZHANG, LI I | UNIVERSITY OF SOUTHERN CALIFORNIA, CA | $4,225,053 | ZMH1 |
| 2017 | Revealing circuit control of neuronal excitation with next-generation voltage indicators1RF1MH114105-01 | CLANDININ, THOMAS ROBERTLIN, MICHAEL Z. | STANFORD UNIVERSITY, CA | $2,893,914 | ZMH1 |
| 2017 | High throughput mapping of neuronal circuitry using DNA sequencing1RF1MH114132-01 | ZADOR, ANTHONY M | COLD SPRING HARBOR LABORATORY, NY | $2,723,622 | ZMH1 |
| 2017 | A General Approach for the Development of New Cell-Type-Specific Viral Vectors1RF1MH114081-01 | GREENBERG, MICHAEL ELDON | HARVARD MEDICAL SCHOOL, MA | $2,446,424 | ZMH1 |
| 2017 | Split RNA polymerases for sensitive, multidimensional analysis of intercellular PPIs at synapses1RF1MH114102-01 | DICKINSON, BRYANOZKAN, ENGIN | UNIVERSITY OF CHICAGO, IL | $2,299,353 | ZMH1 |
| 2017 | High Throughput Approaches for Cell-Specific Synapse Characterization1RF1MH114103-01 | BARTH, ALISON LBRUCHEZ, MARCEL P | CARNEGIE-MELLON UNIVERSITY, PA | $2,194,397 | ZMH1 |
| 2017 | Nano-switches for optogenetic control of neuronal proteins with ultra-specificity1RF1MH114079-01 | WANG, LEI | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $1,751,778 | ZMH1 |
| 2017 | Cerebellar network mapping with a high-throughput TEM platform1RF1MH114047-01 | LEE, WEI-CHUNG ALLEN | HARVARD MEDICAL SCHOOL, MA | $1,271,250 | ZMH1 |
| 2017 | Develop and validate novel chemogenetic tools to modulate synaptic transmission1RF1MH114078-01 | TOMITA, SUSUMU | YALE UNIVERSITY, CT | $1,256,250 | ZMH1 |
| 2017 | Brain circuit mapping using light inducible recombinase systems1RF1MH114106-01 | CETIN, ALI HAYDAR | ALLEN INSTITUTE, WA | $1,080,298 | ZMH1 |
| 2016 | In situ transcriptional analysis of brain circuits at single cell resolution1R01MH111502-01 · under RFA-MH-16-775 | DULAC, CATHERINEREGEV, AVIVZHUANG, XIAOWEI | HARVARD UNIVERSITY, MA | $1,593,922 | ZMH1 |
| 2016 | Mapping and controlling gene expression in inhibitory interneurons mammals1R01MH111529-01 · under RFA-MH-16-775 | FISHELL, GORDON J | NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY | $1,124,687 | ZMH1 |
| 2016 | Next-gen Opto-GPCRs: spatiotemporal simulation of neuromodulator signaling1R01MH111520-01 · under RFA-MH-16-775 | BRUCHAS, MICHAEL R.SUNAHARA, ROGER K | WASHINGTON UNIVERSITY, MO | $1,103,836 | ZMH1 |
| 2016 | Developing a noninvasive method to manipulate specific cell types within the mammalian brain1R01MH111534-01 · under RFA-MH-16-775 | CHALASANI, SREEKANTH H. | SALK INSTITUTE FOR BIOLOGICAL STUDIES, CA | $1,035,349 | ZMH1 |
| 2016 | Realization of Optical Cell-based Reporters for in vivo Detection of Neuropeptides1R01MH111499-01 · under RFA-MH-16-775 | KLEINFELD, DAVIDSLESINGER, PAUL A | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY | $996,914 | ZMH1 |
| 2016 | A platform for high-throughput production of targeting systems for cell-type-specific transgene expression in wild-type animals1R01MH111503-01 · under RFA-MH-16-775 | WICKERSHAM, IAN R | MASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA | $993,992 | ZMH1 |
| 2016 | Multiparametric Biosensor Imaging in Brain Slices1R01MH111527-01 · under RFA-MH-16-775 | BLANPIED, THOMAS AMEREDITH, ANDREA LRIZZO, MEGAN A | UNIVERSITY OF MARYLAND BALTIMORE, MD | $635,832 | ZMH1 |
| 2016 | Multiplex in vivo imaging of cell-specific and circuit-specific signaling pathways during synaptic plasticity1R01MH111516-01 · under RFA-MH-16-775 | HUGANIR, RICHARD LZHANG, JIN | JOHNS HOPKINS UNIVERSITY, MD | $619,950 | ZMH1 |
| 2016 | Optogenetic signaling inhibitors for studying brain plasticity1R01MH111486-01 · under RFA-MH-16-775 | GAN, WENBIAOYASUDA, RYOHEI | MAX PLANCK FLORIDA CORPORATION, FL | $482,250 | ZMH1 |
| 2015 | AN INDUCIBLE MOLECULAR MEMORY SYSTEM TO RECORD TRANSIENT STATES OF CNS CELLS1U01MH109133-01 · under RFA-MH-15-225 | MITRA, ROBI D | WASHINGTON UNIVERSITY, MO | $1,146,862 | ZMH1 |
| 2015 | Intrabody-dependent activation of cell-specific gene expression in CNS1U01MH109102-01 · under RFA-MH-15-225 | BLACKSHAW, SETH | JOHNS HOPKINS UNIVERSITY, MD | $1,048,356 | ZMH1 |
| 2015 | SYNPLA: A scaleable method for monitoring circuit-specific learning-induced changes in synaptic strength1U01MH109113-01 · under RFA-MH-15-225 | MALINOW, ROBERTOZADOR, ANTHONY M | COLD SPRING HARBOR LABORATORY, NY | $1,005,931 | ZMH1 |
| 2015 | Tracing Brain Circuits by Transneuronal Control of Transcription1U01MH109147-01 · under RFA-MH-15-225 | HONG, ELIZABETH JENNIFERLOIS, CARLOSZINN, KAI G | CALIFORNIA INSTITUTE OF TECHNOLOGY, CA | $936,185 | ZMH1 |
| 2015 | Anion channelrhodopsin-based viral tools to manipulate brain networks in behaving animals1U01MH109146-01 · under RFA-MH-15-225 | DRAGOI, VALENTINJANZ, ROGERSPUDICH, JOHN LEE | UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX | $931,074 | ZMH1 |
| 2015 | BRAIN Initiative: Integrated Multimodal Analysis of Cell and Circuit-Specific Processes in Hippocampal Function1U01MH109062-01 · under RFA-MH-15-225 | SWEEDLER, JONATHAN V. | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL | $778,402 | ZMH1 |
| 2015 | A new strategy for cell-type specific gene disruption in flies and mice1U01MH109119-01 · under RFA-MH-15-225 | CLANDININ, THOMAS ROBERTSHAH, NIRAO MAHESH | STANFORD UNIVERSITY, CA | $750,263 | ZMH1 |
| 2015 | Anterograde monosynaptic tracing1U01MH109129-01 · under RFA-MH-15-225 | WICKERSHAM, IAN R | MASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA | $728,000 | ZMH1 |
| 2015 | Novel tools for cell-specific imaging of functional connectivity and circuit operations1U01MH109069-01 · under RFA-MH-15-225 | ISACOFF, EHUD | UNIVERSITY OF CALIFORNIA BERKELEY, CA | $705,670 | ZMH1 |
| 2015 | Generating Multiple Circuit and Neuron Type Specific AAV Vectors With Cross-Species Applicability1U01MH109107-01 · under RFA-MH-15-225 | HE, ZHIGANG | BOSTON CHILDREN'S HOSPITAL, MA | $700,563 | ZMH1 |
| 2015 | Sub-micrometer x-ray tomography for neuroanatomy1U01MH109100-01 · under RFA-MH-15-225 | JACOBSEN, CHRIS JOHNSONKORDING, KONRAD P. | NORTHWESTERN UNIVERSITY, IL | $677,177 | ZMH1 |
| 2015 | Sparse, Strong and Large Area Targeting of Genetically Encoded Indicators1U01MH109091-01 · under RFA-MH-15-225 | ANTIC, SRDJAN DKNOPFEL, THOMAS | UNIVERSITY OF CONNECTICUT SCH OF MED/DNT, CT | $549,797 | ZMH1 |
| 2015 | LIPS: A novel technology for spatial and temporal control of protein synthesis in dendritic spines1U01MH109087-01 · under RFA-MH-15-225 | GAN, WENBIAOJAFFREY, SAMIE R | WEILL MEDICAL COLL OF CORNELL UNIV, NY | $525,875 | ZMH1 |
| 2015 | Genetic tools and imaging technology for mapping cholinergic engrams of anxiety1U01MH109104-01 · under RFA-MH-15-225 | ROLE, LORNA W | STATE UNIVERSITY NEW YORK STONY BROOK, NY | $479,913 | ZMH1 |
| 2015 | Engineered viral tropism for cell-type specific manipulation of neuronal circuits1U01MH109038-01 · under RFA-MH-15-225 | SCHMIDT, DANIELTHOMAS, MARK JOHN | UNIVERSITY OF MINNESOTA, MN | $357,250 | ZMH1 |
| 2014 | DREADD2.0: AN ENHANCED CHEMOGENETIC TOOLKIT1U01MH105892-01 · under RFA-MH-14-216 | JIN, JIANKASH, THOMAS L.ROTH, BRYAN L. | UNIV OF NORTH CAROLINA CHAPEL HILL, NC | $997,398 | ZMH1 |
| 2014 | Mapping neuronal chloride microdomains1U01MH106013-01 · under RFA-MH-14-216 | STALEY, KEVIN J. | MASSACHUSETTS GENERAL HOSPITAL, MA | $913,294 | ZMH1 |
| 2014 | Ultra-Multiplexed Nanoscale In Situ Proteomics for Understanding Synapse Types1U01MH106011-01 · under RFA-MH-14-216 | BATHE, MARKBOYDEN, EDWARD S.YIN, PENG | MASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA | $735,278 | ZMH1 |
| 2014 | Novel technologies for nontoxic transsynaptic tracing1U01MH106018-01 · under RFA-MH-14-216 | WICKERSHAM, IAN R | MASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA | $699,916 | ZMH1 |
| 2014 | Developing drivers for neuron type-specific gene expression1U01MH105924-01 · under RFA-MH-14-216 | HOBERT, OLIVER | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $626,021 | ZMH1 |
| 2014 | Novel Genetic Strategy for Sparse Labeling and Manipulation of Mammalian Neurons1U01MH106008-01 · under RFA-MH-14-216 | YANG, XIANGDONG WILLIAM | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $592,089 | ZMH1 |
| 2014 | In-vivo circuit activity measurement at single cell, sub-threshold resolution1U01MH106027-01 · under RFA-MH-14-216 | FOREST, CRAIGSTANLEY, GARRETT B. | GEORGIA INSTITUTE OF TECHNOLOGY, GA | $504,959 | ZMH1 |
| 2014 | Identification of enhancers whose activity defines cortical interneuron types1U01MH105948-01 · under RFA-MH-14-216 | RUBENSTEIN, JOHN L. R.SOHAL, VIKAAS SINGH | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $487,159 | ZMH1 |
| 2014 | An optogenetic toolkit for the interrogation and control of single cells.1U01MH106035-01 · under RFA-MH-14-216 | HANNON, GREGORY J | COLD SPRING HARBOR LABORATORY, NY | $452,400 | ZMH1 |
| 2014 | Remote regulation of neural activity1U01MH105941-01 · under RFA-MH-14-216 | STANLEY, SARAH AMY | ROCKEFELLER UNIVERSITY, NY | $419,503 | ZMH1 |
Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-10-0.1.1. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.