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NIH funding notice RFA-RM-22-019

NIH Directors New Innovator Award Program (DP2 Clinical Trial Optional)

Closed on August 19, 2022.

Posted
April 7, 2022
Close date
August 19, 2022
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

57 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $80,829,540 in first-year total cost, median $1,408,500.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 RCCS-A (70)]29
  2. Special Emphasis Panel[ZRG1 RCCS-L (70)]28

Most frequent institutions

  1. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO5
  2. BRIGHAM AND WOMEN'S HOSPITAL2
  3. DUKE UNIVERSITY2
  4. HARVARD MEDICAL SCHOOL2
  5. PURDUE UNIVERSITY2
Competing awards under RFA-RM-22-019 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2023Studying the Regulatory Dynamics with Single-cell Multiomics1DP2GM154011-01ZHU, CHENXUNEW YORK GENOME CENTER, NY$1,737,000ZRG1
2023IDENTIFYING MICROBIAL MECHANISMS THAT REGULATE ANIMAL INSULIN SIGNALING1DP2DK139569-01BURTON, NICHOLAS OVAN ANDEL RESEARCH INSTITUTE, MI$1,710,000ZRG1
2023Tracking the Mechanisms of Adaptation to Autophagy Inhibition1DP2CA290705-01TOWERS, CHRISTINA GSALK INSTITUTE FOR BIOLOGICAL STUDIES, CA$1,710,000ZRG1
2023Identifying neurons for interoception using simultaneous profiling of activity- and projection- specific populations1DP2DA060436-01STERN, SARAHMAX PLANCK FLORIDA CORPORATION, FL$1,699,800ZRG1
2023Illuminating neurodegenerative tauopathy from somatic genomic landscapes of single human brain cells1DP2AG086138-01MILLER, MICHAEL BBRIGHAM AND WOMEN'S HOSPITAL, MA$1,611,000ZRG1
2023Engineering programmable enzymes for proteome editing1DP2GM154013-01ZHOU, XINDANA-FARBER CANCER INST, MA$1,602,000ZRG1
2023Defining the universal genomic language of hallmarks in tumor development1DP2CA290196-01DIETLEIN, FELIXBOSTON CHILDREN'S HOSPITAL, MA$1,593,000ZRG1
2023Investigating Genetic and Epigenetic Control of T Cell Function in Autoimmunity1DP2AI183504-01RAY, JOHN PHILIPBENAROYA RESEARCH INST AT VIRGINIA MASON, WA$1,559,700ZRG1
2023Unraveling Neural Circuitry in Peripheral Cancer Pathogenesis: From Local Innervation to Systemic Influences1DP2CA290968-01VENKATESH, HUMSABRIGHAM AND WOMEN'S HOSPITAL, MA$1,535,160ZRG1
2023Capturing, quantifying, and understanding combinatorial effects in small molecule signaling1DP2GM154152-01JOST, MARCOHARVARD MEDICAL SCHOOL, MA$1,525,500ZRG1
2023Visualizing mechanisms at the intersection of chromatin, transcription, and epigenetics1DP2ES036404-01FARNUNG, LUCASHARVARD MEDICAL SCHOOL, MA$1,525,500ZRG1
2023Studying the cellular ecology of organ formation using a novel tissue reconstitution system1DP2DE033856-01SHYER, AMY ELIZABETHROCKEFELLER UNIVERSITY, NY$1,525,500ZRG1
2023Spatial single-cell analysis of somatic mutation in human brain during aging and neurodegeneration1DP2AG086139-01LODATO, MICHAEL ANTHONYUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$1,507,500ZRG1
2023Base-Editing the Cancer Kinome to Enable Drug Discovery1DP2CA290245-01VASAN, NEILCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$1,480,500ZRG1
2023How do animals learn the structure of their natural environment?1DP2MH136496-01FERNANDEZ-RUIZ, ANTONIOCORNELL UNIVERSITY, NY$1,476,000ZRG1
2023Decoding the fundamental principles of autonomous clocks: mechanism, design and function1DP2GM154328-01AYDOGAN, MUSTAFA GONENCUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$1,453,500ZRG1
2023A physiologically-focused approach to training multi-modality AI algorithms in medicine1DP2HL174046-01TISON, GEOFFREY HUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$1,453,500ZRG1
2023Simulating Ancestrally Unbiased Tumor Evolution To Interrogate Drug Resistance1DP2CA290244-01BOSE, ROHITUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$1,453,500ZRG1
2023Live-Cell Chromatin Imaging and Biology: Application to Extrachromosomal DNA1DP2GM154017-01XIE, LIANGQICLEVELAND CLINIC LERNER COM-CWRU, OH$1,449,000ZRG1
2023Optogenetic engineering of tumor topography in native tissue environments1DP2CA290967-01MADDIPATI, RAVIKANTHUT SOUTHWESTERN MEDICAL CENTER, TX$1,437,358ZRG1
2023Reliable AI for Medical Image Reconstruction1DP2LM014564-01SOLTANOLKOTABI, MAHDIUNIVERSITY OF SOUTHERN CALIFORNIA, CA$1,434,445ZRG1
2023Protecting microbes so they can protect us1DP2GM154015-01FURST, ARIEL LESAMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$1,431,000ZRG1
2023Functional, Structural and Molecular Decoding of Astrocyte-Neuron Interaction1DP2NS136871-01YU, XINZHUUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$1,427,400ZRG1
2023Harnessing stem cells and synthetic gene circuits to repair glomerular injury1DP2DK139544-01MUSAH, SAMIRADUKE UNIVERSITY, NC$1,425,761ZRG1
2023Probing sex differences in myocardial fibrosis at multiple length scales using biomaterials1DP2HL173948-01AGUADO, BRIAN ALBERTOUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$1,422,000ZRG1
2023Unraveling the synaptic and circuit mechanisms underlying a plasticity-driving instructive signal1DP2MH136393-01GRIENBERGER, CHRISTINEBRANDEIS UNIVERSITY, MA$1,415,167ZRG1
2023Activity-dependent probes for spatially-defined proteomics1DP2MH136588-01KIM, CHRISTINAUNIVERSITY OF CALIFORNIA AT DAVIS, CA$1,414,340ZRG1
2023Innovations in Personalizing Treatment for Eating Disorders Using Idiographic Methods and the Impact of Personalization on Psychological, Physical, and Sociodemographic Outcomes1DP2MH136495-01LEVINSON, CHERI ALICIAUNIVERSITY OF LOUISVILLE, KY$1,411,981ZRG1
2023Monitoring neuronal activity with a blood test - Released Markers of Activity (RMA)1DP2EB035905-01SZABLOWSKI, JERZY OLGIERDRICE UNIVERSITY, TX$1,408,500ZRG1
2023Cellular FM-radios: seeing, probing, and perturbing single-cell protein activity dynamics in biological systems with frequency-barcoded spatiotemporal signaling circuits1DP2GM154329-01COYLE, SCOTT M.UNIVERSITY OF WISCONSIN-MADISON, WI$1,399,500ZRG1
2023Uncovering the regulatory logic of gene expression encoded by disordered regions1DP2CA290639-01HOLEHOUSE, ALEX SWASHINGTON UNIVERSITY, MO$1,399,500ZRG1
2023Defining and Exploiting the Circadian Clocks in Malaria Parasites1DP2GM154010-01RIJO-FERREIRA, FILIPAUNIVERSITY OF CALIFORNIA BERKELEY, CA$1,399,125ZRG1
2023Decoding natural protective mechanisms during diapause and longevity to counter aging1DP2AG086979-01SINGH, PARAM PRIYAUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$1,395,075ZRG1
2023Deep phenotyping of fusion oncoprotein-driven pediatric cancer metastasis with single-cell proteomics1DP2CA290802-01VLASSAKIS, JULEARICE UNIVERSITY, TX$1,389,742ZRG1
2023Vascular mural cells in the development of the blood brain barrier1DP2MH136391-01CROUCH, ELIZABETH ERINUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$1,388,925ZRG1
2023Mapping and Therapeutic Hijacking of Lysosomal Transport1DP2GM154016-01BANIK, STEVENSTANFORD UNIVERSITY, CA$1,385,226ZRG1
2023Measuring input-output operations of cortical neurons with large-scale neurotransmitter imaging1DP2NS136990-01PODGORSKI, KASPARALLEN INSTITUTE, WA$1,385,000ZRG1
2023Decoding the Spatial Grammar of Developmental Signaling1DP2HD115158-01LORD, NATHAN DALEUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$1,383,800ZRG1
2023Addressing Cervical Cancer Disparities Among People Experiencing Homelessness1DP2MD019356-01RODRIGUEZ, NATALIA MARIAPURDUE UNIVERSITY, IN$1,382,625ZRG1
2023Functional maturation of neural circuits for biological motion perception and social engagement1DP2EY036251-01LOVETT-BARRON, MATTHEWUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$1,378,728ZRG1
2023The facts of the matter: decoding the molecular properties of brain white matter using cell-type-specific quantitative proteomics1DP2NS136873-01BALDWIN, KATHERINE THERESEUNIV OF NORTH CAROLINA CHAPEL HILL, NC$1,377,516ZRG1
2023A biochemical approach towards subcellular, label-free molecular imaging1DP2MH136390-01GAO, RUIXUANUNIVERSITY OF ILLINOIS AT CHICAGO, IL$1,372,964ZRG1
2023Droplet-based Spatially Encoded Live Cell Digital Extraction1DP2GM154018-01KO, JINAUNIVERSITY OF PENNSYLVANIA, PA$1,368,750ZRG1
2023Under Pressure: Biophysical Mapping of Herpesvirus Capsid Assembly and Genome Packaging1DP2GM154151-01DRAGANOVA, ELIZABETH BENNETTEMORY UNIVERSITY, GA$1,367,863ZRG1
2023Enzymatic and genetic strategies for targeting disease-associated microbial metabolites1DP2GM154019-01LI, JIAHEUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$1,355,273ZRG1
2023Imaging Spatiotemporal Regulation of Acetyl-CoA1DP2GM154012-01SCHMITT, DANIELLE LYNANNEUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$1,354,522ZRG1
2023A Novel Class of Synthetic Receptors to Empower the Age of mRNA Therapies1DP2EB035891-01GAO, XIAOJING JSTANFORD UNIVERSITY, CA$1,350,770ZRG1
2023Water Emergency Team (WET): Community-Driven Rapid Response Team to Evaluate Antibiotic-Resistant Bacteria Exposures and Household Environmental Health Risks from Sewer Overflows and Basement Flooding1DP2MD019355-01GOLDSTEIN, RACHEL EUNIV OF MARYLAND, COLLEGE PARK, MD$1,345,283ZRG1
2023Reactivating regulatory programs for regeneration1DP2HL173858-01MARTIK, MEGAN LEEUNIVERSITY OF CALIFORNIA BERKELEY, CA$1,344,373ZRG1
2023Molecular determinants of host-feeding manipulation and microbial colonization1DP2GM154014-01ODONNELL, MICHAEL PATRICKYALE UNIVERSITY, CT$1,338,750ZRG1
2023A Paradigm Shift in Health Behavior Change: Understanding When and How Social Comparison Supports Healthy Behavior1DP2HL173857-01ARIGO, DANIELLEROWAN UNIVERSITY, NJ$1,336,496ZRG1
2023Bioengineering Tools to Resolve and Manipulate Neuroimmune Signaling1DP2MH136493-01BARTELLE, BENJAMIN BARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$1,336,458ZRG1
2023Brewing anti-toxin drugs using probiotic yeast1DP2AT012795-01CROOK, NATHAN C.NORTH CAROLINA STATE UNIVERSITY RALEIGH, NC$1,333,682ZRG1
2023Multi-scale feedbacks for robust organ development1DP2HD115157-01MUNJAL, AKANKSHIDUKE UNIVERSITY, NC$1,319,060ZRG1
2023Crowd-Powered Machine Learning to Diagnose ASD and ADHD in Adolescents from Digital Social Interactions1DP2EB035858-01WASHINGTON, PETERUNIVERSITY OF HAWAII AT MANOA, HI$1,309,500ZRG1
2023Massively scalable 3D electrophysiology and two-photon imaging in freely-moving animals1DP2MH136494-01JAYANT, KRISHNAPURDUE UNIVERSITY, IN$1,304,216ZRG1
2023Sensory Augmentation, Restoration, and Modulation Using a Spinal Neuroprosthesis1DP2NS136872-01YADAV, AMOL PINDIANA UNIVERSITY INDIANAPOLIS, IN$191,206ZRG1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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