| #1 | Vanderbilt University Medical Center | Nashville | School Of Medicine | $429M | 586 | 600 |
| #2 | Vanderbilt University | Nashville | School Of Medicine | $122.4M | 369 | 342 |
| #3 | St. Jude Children's Research Hospital | Memphis | Hospital | $109.4M | 165 | 138 |
| #4 | University of Tennessee Health Science Center | Memphis | University | $44.5M | 90 | 99 |
| #5 | University of Tennessee Knoxville | Knoxville | University | $11.7M | 34 | 33 |
| #6 | Meharry Medical College | Nashville | School Of Medicine | $8.1M | 24 | 34 |
| #7 | East Tennessee State University | Johnson City | University | $5.6M | 17 | 15 |
| #8 | University of Memphis | Memphis | University | $2.7M | 14 | 18 |
| #9 | Tennessee State University | Nashville | University | $1.5M | 6 | 11 |
| #10 | Tn State Department of Agriculture | Nashville | Other | $1.5M | 5 | 4 |
| #11 | Baptist Memorial Hospital - Tipton | Covington | Hospital | $1.4M | 1 | 1 |
| #12 | Volumetrix, LLC | Nashville | Other | $1.2M | 3 | 2 |
| #13 | Tavo Biotherapeutics, Inc | Memphis | Other | $1.2M | 3 | 1 |
| #14 | Oak Ridge Associated Universities | Oak Ridge | Other | $1.2M | 1 | 3 |
| #15 | Yaya Scientific, LLC | Franklin | Other | $1.1M | 1 | 1 |
| #16 | Healing Innovations Inc | Nashville | Other | $1M | 1 | 2 |
| #17 | Endotheia, Inc. | Nashville | Other | $1M | 2 | 1 |
| #18 | Immuno Technologies, Inc. | Memphis | Other | $999.9K | 1 | 1 |
| #19 | Very Real Help, LLC | Nashville | Other | $910.4K | 1 | 1 |
| #20 | Virtuoso Surgical, Inc. | Nashville | Other | $908.1K | 1 | 1 |
| #21 | Tennessee State Department of Health | Nashville | Other | $874.5K | 6 | 6 |
| #22 | Myriad Sensors, Inc. | Brentwood | Other | $864.1K | 1 | 1 |
| #23 | Middle Tennessee State University | Murfreesboro | University | $625.1K | 3 | 3 |
| #24 | University of Tennessee Chattanooga | Chattanooga | University | $396.8K | 1 | 1 |
| #25 | Oak Ridge National Laboratory | Oak Ridge | Other | $377.3K | 1 | 1 |
| #26 | Pediadose LLC | Gallatin | Other | $333.6K | 1 | 1 |
| #27 | St. Jude Children's Research Hospital Graduate School of Biomedical Sciences, LLC | Memphis | Hospital | $316.3K | 8 | 8 |
| #28 | College On Problems of Drug Dependence | Brentwood | University | $95K | 1 | 1 |
| #29 | University of Tennessee Martin | Martin | University | $88.2K | 1 | 1 |
| #30 | International Mammalian Genome Society | Oak Ridge | Other | $56.5K | 1 | 1 |
