Biochemistry at Columbia University

Leads a grant in this department

33 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Leong, Kam W

   Leads 2 awards · $1,977,406

   • 5UG3TR002151-02Department: NIH department code

     Integrated Microphysiological System of Cerebral Organoid and Blood Vessel for Disease Modeling and Neuropsychiatric Drug screening
     $1,178,937

     award amount
   • 1UG3NS115598-01Department: NIH department code

     Focused Ultrasound-mediated Delivery of Gene-editing Elements to the Brain for Neurodegenerative Disorders
     $798,469

     award amount

2. Fitzpatrick, Anthony William Paul

   Leads 1 award · $1,434,762

   • 5U01NS110438-02Department: NIH department code

     Patient-Based Structural Biology of Tauopathies and TDP-43 Proteinopathies using Cryo-Electron Microscopy and Mass Spectrometry
     $1,434,762

     award amount

3. Vitkup, Dennis

   Leads 2 awards · $1,136,441

   • 5R01DK118044-02Department: NIH department code

     Ecological dynamics and metabolic interactions in thegut microbiome across space and time
     $697,080

     award amount
   • 1R35GM131884-01Department: NIH department code

     Systems Biology of Protein and Phenotypic Evolution
     $439,361

     award amount

4. Mann, Richard S

   Leads 2 awards · $1,075,961

   • 5R35GM118336-04Department: NIH department code

     Interpreting and Deploying Genomic Information During Animal Development
     $608,052

     award amount
   • 5R01NS070644-10Department: NIH department code

     Development and function of an adult locomotion circuit in Drosophila
     $467,909

     award amount

5. Lomvardas, Stavros

   Leads 2 awards · $1,042,045

   • 1R56AG062454-01Department: NIH department code

     Anosmia as a predictor of preclinical Alzheimer's disease
     $649,633

     award amount
   • 5R01DC015451-04Department: NIH department code

     Deciphering the molecular principles of olfactory receptor gene choice
     $392,412

     award amount

6. Tavazoie, Saeed F

   Leads 2 awards · $1,036,527

   • 5R01HG009065-05Department: NIH department code

     Massively parallel mapping of all molecular interactions in a single tube
     $610,261

     award amount
   • 5R01AI077562-10Department: NIH department code

     Comprehensive genetic analysis of antibiotic persistence
     $426,266

     award amount

7. Shapiro, Lawrence S

   Leads 2 awards · $939,976

   • 5R01AR073846-02Department: NIH department code

     Structure and mechanism of pemphigus autoantibodies
     $492,118

     award amount
   • 5R01GM118584-03Department: NIH department code

     Structure and Function of Desmosomal Cadherins
     $447,858

     award amount

8. Brown, Lewis M.

   Leads 2 awards · $909,880

   • 5U01DA040582-05Department: NIH department code

     Deciphering nuclear bodies and compartments that govern singular olfactory receptor expression.
     $573,246

     award amount
   • 3U01DA040582-05S1Department: NIH department code

     Deciphering nuclear bodies and compartments that govern singular olfactory receptor expression.
     $336,634

     award amount

9. Greene, Eric C

   Leads 2 awards · $893,656

   • 5R35GM118026-04Department: NIH department code

     Mechanisms of Genome Integrity
     $523,081

     award amount
   • 1R01CA236606-01Department: NIH department code

     Helicase regulation during homologous recombination
     $370,575

     award amount

10. Maniatis, Thomas P

    Leads 2 awards · $880,094

    • 5R01MH114817-07Department: NIH department code

      The structural basis of cis and trans protocadherin interactions
      $480,094

      award amount
    • 5R01MH108579-04Department: NIH department code

      Role of the protocadherin alpha gene cluster in serotonergic circuitry formation and its implications in depressive disorders
      $400,000

      award amount

11. Frank, Joachim

    Leads 2 awards · $859,283

    • 5R01GM029169-37Department: NIH department code

      Structural Analysis of Macromolecular Assemblies
      $497,847

      award amount
    • 2R01GM055440-22Department: NIH department code

      Time-resolved Cryo-EM of Short-lived States in Eukaryotic Translation
      $361,436

      award amount

12. Zhang, Chaolin

    Leads 2 awards · $787,098

    • 5R01GM124486-02Department: NIH department code

      Single-nucleotide resolution mapping of allelic protein-RNA interactions and splicing-regulatory variants
      $441,752

      award amount
    • 5R01NS089676-05Department: NIH department code

      RNA regulatory networks in motor neuron development and function
      $345,346

      award amount

13. Sobolevsky, Alexander

    Leads 2 awards · $754,272

    • 5R01CA206573-03Department: NIH department code

      Structure and function of Transient Receptor Potential channels
      $380,184

      award amount
    • 5R01NS107253-02Department: NIH department code

      Single-particle cryo-EM characterization of AMPA receptor functional states
      $374,088

      award amount

14. Landweber, Laura F

    Leads 1 award · $727,524

    • 5R35GM122555-03Department: NIH department code

      Understanding Complex Gene Editing Systems and RNA Biology in Oxytricha
      $727,524

      award amount

15. Mueller, Ulrich

    Leads 1 award · $649,303

    • 5R01DC016960-02Department: NIH department code

      Integrative Structural and Functional Characterization of Tip-Link Cadherins Deafness
      $649,303

      award amount

16. Wang, Harris H

    Leads 1 award · $612,352

    • 5R01AI132403-03Department: NIH department code

      Micron-scale Spatial Metagenomic Mapping of Microbial Biogeography in the Gastrointestinal Tract
      $612,352

      award amount

17. Vander Heiden, Matthew G.

    Leads 1 award · $563,778

    • 5R01CA201276-04Department: NIH department code

      Analysis of cancer cell metabolism in diverse environmental conditions
      $563,778

      award amount

18. Hendrickson, Wayne A.

    Leads 2 awards · $556,142

    • 5R01GM107462-06Department: NIH department code

      Atomic Level Analysis of Biomolecular Structure
      $396,857

      award amount
    • 3R01GM107462-06S1Department: NIH department code

      Atomic Level Analysis of Biomolecular Structure
      $159,285

      award amount

19. Kurnikova, Maria G

    Leads 1 award · $501,861

    • 5R01NS083660-07Department: NIH department code

      Structure and Function of AMPA subtype ionotropic glutamate receptors
      $501,861

      award amount

20. Shen, Yufeng

    Leads 2 awards · $490,182

    • 5R01GM120609-03Department: NIH department code

      Integrate cancer genomics data in genetic studies and diagnosis of developmental disorders
      $332,608

      award amount
    • 1R03HL147197-01Department: NIH department code

      Integrate gene expression data to characterize the contribution of rare genetic risk factors to structural birth defects
      $157,574

      award amount

21. Palmer, Arthur G

    Leads 1 award · $470,009

    • 1R35GM130398-01Department: NIH department code

      Macromolecular dynamics and conformational changes in biological function
      $470,009

      award amount

22. Shapira, Sagi

    Leads 2 awards · $420,159

    • 1R21AI147201-01Department: NIH department code

      Leveraging experimental and computational tools to define molecular functions of non-coding RNAs in innate immune responses to viral infection
      $260,000

      award amount
    • 3R01GM109018-05S1Department: NIH department code

      Quantitative Studies of influenza Evolution
      $160,159

      award amount

23. Sia, Samuel K

    Leads 1 award · $394,629

    • 5R01HL141935-02Department: NIH department code

      Injectable microtissues to promote rapid host re-perfusion of ischemic tissues
      $394,629

      award amount

24. Gottesman, Max Elliot

    Leads 1 award · $375,684

    • 5T32DK007328-40Department: NIH department code

      HORMONES: BIOCHEMISTRY AND MOLECULAR BIOLOGY
      $375,684

      award amount

25. Barr, R Graham

    Leads 1 award · $375,146

    • 5R01HL142028-02Department: NIH department code

      Integration of omics data to improve interpretation of genetic risk variants in lung disease
      $375,146

      award amount

26. Sheng, Zizhang

    Leads 1 award · $243,000

    • 5R21AI138024-02Department: NIH department code

      Structural basis of antibody affinity maturation by somatic hypermutation
      $243,000

      award amount

27. Duffie, Rachel

    Leads 1 award · $162,000

    • 1R21DC017823-01Department: NIH department code

      Translational control of sensory identity
      $162,000

      award amount

28. Glassford, William Joseph

    Leads 1 award · $63,746

    • 5F32GM125329-02Department: NIH department code

      The role of protein-protein interaction motifs in coordinating the DNA binding and regulatory specificity of Hox proteins
      $63,746

      award amount

29. Momen-Roknabadi, Amir

    Leads 1 award · $63,746

    • 5F32GM125170-02Department: NIH department code

      Systems Level Characterization of a New Epigenetic Mechanism of Gene Expression and Cellular Adaptation
      $63,746

      award amount

30. Chen, Sway Peng

    Leads 1 award · $50,016

    • 5F30DK111145-03Department: NIH department code

      Novel genetic engineering tools for functional studies of the gut microbiome
      $50,016

      award amount

31. Hobson, Benjamin

    Leads 1 award · $50,016

    • 1F30DA047775-01Department: NIH department code

      Gene Expression Programs in Maturing Dopamine Neurons: Temporal Regulation, Subcellular Localization, and Alteration by Amphetamine
      $50,016

      award amount

32. Luo, Katherine

    Leads 1 award · $42,881

    • 5F31CA236516-02Department: NIH department code

      Characterizing LIN-12/Notch Regulation and Activity
      $42,881

      award amount

33. Horta, Adan

    Leads 1 award · $42,276

    • 5F31DC016785-03Department: NIH department code

      Developmentally dynamic chromatin architecture during neurogenesis
      $42,276

      award amount