Biochemistry at Columbia University

Leads a grant in this department

31 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Chaolin Zhang

   Leads 3 awards · $2,093,449

   • 5R35GM145279-03Department: NIH department code

     Complexity and evolution of splicing-regulatory networks
     $906,022

     award amount
   • 5R01HG012359-02Department: NIH department code

     Mapping proximal and distal splicing-regulatory elements
     $595,863

     award amount
   • 5R01NS125018-03Department: NIH department code

     RNA Regulatory Networks in Neuronal Cell Type Diversity and Function
     $591,564

     award amount

2. Stavros Lomvardas

   Leads 4 awards · $2,092,669

   • 5U01DA052783-05Department: NIH department code

     Interrogating genome folding trajectories in health and disease
     $622,658

     award amount
   • 5R01DC015451-08Department: NIH department code

     Converting stochastic olfactory receptor expression to stereotypic axon guidance programs
     $530,688

     award amount
   • 5R01DC018744-05Department: NIH department code

     Olfactory receptor mRNAs as lncRNAs that regulate genomic interactions
     $480,534

     award amount
   • 5R01DC018745-05Department: NIH department code

     Principles of zonal olfactory receptor gene expression
     $458,789

     award amount

3. Alexander Sobolevsky

   Leads 4 awards · $1,978,984

   • 2R37NS083660-11A1Department: NIH department code

     Structure and Function of Ionotropic Glutamate Receptors
     $574,613

     award amount
   • 5R01AR078814-03Department: NIH department code

     Structural and functional principles of activation and regulation of the transient receptor potential channel TRPV3.
     $568,116

     award amount
   • 5R01CA206573-07Department: NIH department code

     Structure and function of Transient Receptor Potential Channels
     $437,475

     award amount
   • 5R01NS107253-07Department: NIH department code

     Single-Particle Cryo-EM Characterization of AMPA Receptor Functional States
     $398,780

     award amount

4. Sara Zaccara

   Leads 2 awards · $1,656,453

   • 1DP2HD118273-01Department: NIH department code

     Programmable depletion and rescue platform to screen dynamic regulatory events during cellular differentiation.
     $1,463,997

     award amount
   • 5K22CA258954-03Department: NIH department code

     The DF phospho-code regulating the degradation of m6A mRNA
     $192,456

     award amount

5. Harris H Wang

   Leads 3 awards · $1,607,454

   • 5R01AI132403-07Department: NIH department code

     Micron-scale Spatial Metagenomic Mapping of Microbial Biogeography in the Gastrointestinal Tract
     $729,963

     award amount
   • 5R01EB031935-04Department: NIH department code

     A high-performance and versatile technology for precision microbiome engineering

     Principal investigators: Harris H Wang (contact PI), Samuel Henry Sternberg

     $630,741

     award amount
   • 1R21AI183029-01Department: NIH department code

     Profiling diarrhea-predominant irritable bowel syndrome (IBS-D) using stool-based RNAs
     $246,750

     award amount

6. Thomas P Maniatis

   Leads 2 awards · $1,378,693

   • 5R01MH130592-02Department: NIH department code

     The impact of loss of function DNA sequence variants in the human protocadherin gene cluster on neural circuit assembly.
     $753,507

     award amount
   • 5R01MH108579-09Department: NIH department code

     The role of the clustered protocadherins in neural circuit formation and implications for neurodevelopmental disorders
     $625,186

     award amount

7. Eric C Greene

   Leads 3 awards · $1,270,224

   • 5R35GM118026-09Department: NIH department code

     Mechanisms of Genome Integrity
     $551,971

     award amount
   • 5R01CA221858-05Department: NIH department code

     Defining the contributions of BRCA1, BRCA2, and RAD52 to genome stability
     $373,251

     award amount
   • 5R01CA236606-06Department: NIH department code

     Helicase regulation during homologous recombination
     $345,002

     award amount

8. Richard S Mann

   Leads 2 awards · $1,078,256

   • 5R35GM118336-09Department: NIH department code

     Interpreting and Deploying Genomic Information During Animal Development
     $630,577

     award amount
   • 5R01NS070644-15Department: NIH department code

     Development and Function of an Adult Locomotion Circuit in Drosophila
     $447,679

     award amount

9. Laura F Landweber

   Leads 3 awards · $969,523

   • 5R35GM122555-08Department: NIH department code

     Understanding Complex Genome Editing and RNA Biology in Oxytricha
     $771,697

     award amount
   • 3R35GM122555-08S1Department: NIH department code

     Understanding Complex Genome Editing and RNA Biology in Oxytricha
     $147,973

     award amount
   • 3R35GM122555-08S2Department: NIH department code

     Understanding Complex Genome Editing and RNA Biology in Oxytricha
     $49,853

     award amount

10. Saeed F Tavazoie

    Leads 2 awards · $869,260

    • 5R01AI077562-15Department: NIH department code

      Systems biological interrogation of bacterial persistence
      $530,830

      award amount
    • 5R01CA257153-04Department: NIH department code

      Mapping the regulatory landscape of RNA binding proteins and their causal roles in tumorigenesis and patient survival

      Principal investigators: Saeed F Tavazoie (contact PI), Sohail F. Tavazoie

      $338,430

      award amount

11. Joachim Frank

    Leads 2 awards · $818,507

    • 5R35GM139453-04Department: NIH department code

      Structural Studies of Macromolecular Assemblies Using Cryo-EM
      $767,819

      award amount
    • 3R35GM139453-04S1Department: NIH department code

      Structural Studies of Macromolecular Assemblies Using Cryo-EM
      $50,688

      award amount

12. Hashim M Al-Hashimi

    Leads 1 award · $805,019

    • 5R01AI178848-02Department: NIH department code

      Development and application of a quantitive model for HIV-1 transcriptional activation driven by TAR RNA conformational dynamics

      Principal investigators: Hashim M Al-Hashimi (contact PI), Daniel Herschlag, Stephen Paine Goff

      $805,019

      award amount

13. Harmen J Bussemaker

    Leads 1 award · $776,594

    • 5R01MH106842-08Department: NIH department code

      Integrative analysis of genetic variation and transcription factor networks to elucidate mechanisms of mental health disorders

      Principal investigators: Harmen J Bussemaker (contact PI), Tuuli Lappalainen

      $776,594

      award amount

14. Dennis Vitkup

    Leads 1 award · $752,885

    • 5R01MH124923-05Department: NIH department code

      Discovery and analysis of brain circuits and cell types affected in autism and schizophrenia

      Principal investigators: Dennis Vitkup (contact PI), Joseph A Gogos

      $752,885

      award amount

15. Samuel K Sia

    Leads 1 award · $638,942

    • 1R01AI181318-01Department: NIH department code

      Degradable bioplastics for microfluidic diagnostic assays towards improved environmental and human health
      $638,942

      award amount

16. Arthur G Palmer

    Leads 1 award · $628,140

    • 2R35GM130398-06Department: NIH department code

      Macromolecular dynamics and conformational changes in biological function
      $628,140

      award amount

17. Stephen Paine Goff

    Leads 1 award · $560,787

    • 5R01CA030488-43Department: NIH department code

      Mechanisms of Silencing of Retroviral DNAs in Embryonic Cell Lines
      $560,787

      award amount

    Also a principal investigator on 5R01AI178848-02, led by Hashim M Al-Hashimi.

18. Anum Azam Glasgow

    Leads 2 awards · $485,776

    • 5R00GM135529-05Department: NIH department code

      Mapping and rewiring protein allostery
      $249,000

      award amount
    • 1R21EB035208-01A1Department: NIH department code

      Computationally designed, small molecule-responsive cell receptors for treating solid tumors
      $236,776

      award amount

19. Shanti Pal Gangwar

    Leads 1 award · $452,375

    • 1R21NS139087-01Department: NIH department code

      Molecular regulation of Kainate receptors
      $452,375

      award amount

20. Anna-Lena Steckelberg

    Leads 1 award · $411,250

    • 5R35GM150778-02Department: NIH department code

      Understanding the antiviral roles of acellular RNA quality control pathway
      $411,250

      award amount

21. Mohammed Nazar Alquraishi

    Leads 1 award · $411,250

    • 5R35GM150546-02Department: NIH department code

      Machine learning of biomolecular interactions and the human signaling networks they comprise
      $411,250

      award amount

22. Yufeng Shen

    Leads 1 award · $406,912

    • 5R35GM149527-02Department: NIH department code

      Computational methods to interpret genomic variation and integrate functional genomics data in genetic analysis of human diseases
      $406,912

      award amount

23. Joan M. Pulupa

    Leads 2 awards · $201,042

    • 5K99DC021219-02Department: NIH department code

      Identifying the mechanism of olfactory receptor gene regulation in olfactory neurons with live-cell imaging
      $125,442

      award amount
    • 3K99DC021219-02S1Department: NIH department code

      Identifying the mechanism of olfactory receptor gene regulation in olfactory neurons with live-cell imaging
      $75,600

      award amount

24. Jaeseung Hahn

    Leads 1 award · $172,044

    • 1K99CA283259-01A1Department: NIH department code

      Programmable biohybrid system for cancer therapy
      $172,044

      award amount

25. Erin Flaherty

    Leads 1 award · $131,733

    • 5K99MH132889-02Department: NIH department code

      The role of the protocadherin gene cluster in neurodevelopment and the implications for neurodevelopmental disorders
      $131,733

      award amount

26. Sahiti Kuppa

    Leads 1 award · $91,635

    • 5K00CA274696-03Department: NIH department code

      Role of nuclear chaperones in genomic instability and carcinogenesis
      $91,635

      award amount

27. William Francis Kindschuh

    Leads 1 award · $53,974

    • 5F30HD108886-03Department: NIH department code

      Quantifying the interactions among maternal race, vaginal metabolites, and microbes in preterm birth
      $53,974

      award amount

28. Stephen Tang

    Leads 1 award · $50,937

    • 1F30AI183830-01Department: NIH department code

      Mechanisms of reverse transcriptase mediated phage resistance in Enterobacteriaceae
      $50,937

      award amount

29. Rebeca Teresa King

    Leads 1 award · $49,946

    • 5F31HL167530-02Department: NIH department code

      Leveraging CRISPR RNA-guided DNA Transposases for Gene Insertion at the CFTR Locus
      $49,946

      award amount

30. Ariel David Pourmorady

    Leads 1 award · $49,270

    • 5F30DC020900-03Department: NIH department code

      Deciphering mechanisms for olfactory receptor choice in single cells
      $49,270

      award amount

31. Belen Sundberg

    Leads 1 award · $48,974

    • 1F31AI184134-01Department: NIH department code

      Elucidating the complex allosteric regulation of PFK-1, a broadly evolutionarily conserved glycolytic enzyme
      $48,974

      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.

• Daniel Herschlag

  Co-investigator on 5R01AI178848-02, led by Hashim M Al-Hashimi

  From the FY2024 awards this person leads

  • Stanford University · Biochemistry (NIH department code, 1 award)

• Tuuli Lappalainen

  Co-investigator on 5R01MH106842-08, led by Harmen J Bussemaker

  From the FY2024 awards this person leads

  • New York Genome Center (no department on record, 1 award)

• Joseph A Gogos

  Co-investigator on 5R01MH124923-05, led by Dennis Vitkup

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Samuel Henry Sternberg

  Co-investigator on 5R01EB031935-04, led by Harris H Wang

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Sohail F. Tavazoie

  Co-investigator on 5R01CA257153-04, led by Saeed F Tavazoie

  From the FY2024 awards this person leads

  • Rockefeller University · Biology (NIH department code, 1 award)
  • Rockefeller University (no department on record, 3 awards)