Biochemistry at Columbia University

Leads a grant in this department

26 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Chaolin Zhang

   Leads 4 awards · $2,211,577

   • 5R35GM145279-04Department: NIH department code

     Complexity and evolution of splicing-regulatory networks
     $906,022

     award amount
   • 5R01HG012359-03Department: NIH department code

     Mapping proximal and distal splicing-regulatory elements
     $595,863

     award amount
   • 5R01NS125018-04Department: NIH department code

     RNA Regulatory Networks in Neuronal Cell Type Diversity and Function
     $549,057

     award amount
   • 1T32GM158494-01Department: NIH department code

     Columbia University Graduate Training Program in Computational and Systems Biology

     Principal investigators: Chaolin Zhang (contact PI), Peter Alan Sims

     $160,635

     award amount

2. Alexander Sobolevsky

   Leads 4 awards · $1,978,083

   • 5R37NS083660-12Department: NIH department code

     Structure and Function of Ionotropic Glutamate Receptors
     $579,353

     award amount
   • 5R01AR078814-04Department: NIH department code

     Structural and functional principles of activation and regulation of the transient receptor potential channel TRPV3.
     $527,117

     award amount
   • 5R01CA206573-08Department: NIH department code

     Structure and function of Transient Receptor Potential Channels
     $460,501

     award amount
   • 5R01NS107253-08Department: NIH department code

     Single-Particle Cryo-EM Characterization of AMPA Receptor Functional States
     $411,112

     award amount

3. Mohammed Nazar Alquraishi

   Leads 2 awards · $1,852,155

   • 1R01LM014674-01Department: NIH department code

     Fast and slow prediction of stable and transient protein-protein interactions
     $1,440,905

     award amount
   • 5R35GM150546-03Department: NIH department code

     Machine learning of biomolecular interactions and the human signaling networks they comprise
     $411,250

     award amount

4. Thomas P Maniatis

   Leads 2 awards · $1,435,373

   • 5R01MH130592-03Department: NIH department code

     The impact of loss of function DNA sequence variants in the human protocadherin gene cluster on neural circuit assembly.
     $810,187

     award amount
   • 5R01MH108579-10Department: NIH department code

     The role of the clustered protocadherins in neural circuit formation and implications for neurodevelopmental disorders
     $625,186

     award amount

5. Hashim M Al-Hashimi

   Leads 2 awards · $1,257,024

   • 5R01AI178848-03Department: NIH department code

     Development and application of a quantitive model for HIV-1 transcriptional activation driven by TAR RNA conformational dynamics

     Principal investigators: Hashim M Al-Hashimi (contact PI), Daniel Herschlag, Stephen Paine Goff

     $796,527

     award amount
   • 2R01GM089846-15Department: NIH department code

     Role of DNA structural dynamics in mutagenesis and oncogenesis
     $460,497

     award amount

6. Samuel K Sia

   Leads 2 awards · $1,225,608

   • 5R01AI181318-02Department: NIH department code

     Degradable bioplastics for microfluidic diagnostic assays towards improved environmental and human health
     $650,252

     award amount
   • 1R01AI188944-01A1Department: NIH department code

     PRECISE: accessible sample-to-answer RT-PCR detection of hepatitis C infection from whole blood
     $575,356

     award amount

7. Stavros Lomvardas

   Leads 2 awards · $1,150,630

   • 1R01DC022975-01Department: NIH department code

     Solid phase transition as a facilitator of olfactory receptor choice
     $619,942

     award amount
   • 5R01DC015451-09Department: NIH department code

     Converting stochastic olfactory receptor expression to stereotypic axon guidance programs
     $530,688

     award amount

8. Eric C Greene

   Leads 2 awards · $965,894

   • 5R35GM118026-10Department: NIH department code

     Mechanisms of Genome Integrity
     $551,971

     award amount
   • 2R01CA236606-07Department: NIH department code

     Helicase regulation during homologous recombination
     $413,923

     award amount

9. Harris H Wang

   Leads 2 awards · $921,194

   • 5R01AI132403-08Department: NIH department code

     Micron-scale Spatial Metagenomic Mapping of Microbial Biogeography in the Gastrointestinal Tract
     $721,738

     award amount
   • 5R21AI183029-02Department: NIH department code

     Profiling diarrhea-predominant irritable bowel syndrome (IBS-D) using stool-based RNAs
     $199,456

     award amount

10. Laura F Landweber

    Leads 2 awards · $784,028

    • 5R35GM122555-09Department: NIH department code

      Understanding Complex Genome Editing and RNA Biology in Oxytricha
      $771,697

      award amount
    • 3R35GM122555-09S1Department: NIH department code

      Understanding Complex Genome Editing and RNA Biology in Oxytricha
      $12,331

      award amount

11. Joachim Frank

    Leads 1 award · $767,819

    • 5R35GM139453-05Department: NIH department code

      Structural Studies of Macromolecular Assemblies Using Cryo-EM
      $767,819

      award amount

12. Richard S Mann

    Leads 1 award · $630,577

    • 5R35GM118336-10Department: NIH department code

      Interpreting and Deploying Genomic Information During Animal Development
      $630,577

      award amount

13. Arthur G Palmer

    Leads 1 award · $628,140

    • 5R35GM130398-07Department: NIH department code

      Macromolecular dynamics and conformational changes in biological function
      $628,140

      award amount

14. Saeed F Tavazoie

    Leads 1 award · $532,716

    • 5R01CA257153-05Department: NIH department code

      Mapping the regulatory landscape of RNA binding proteins and their causal roles in tumorigenesis and patient survival

      Principal investigators: Saeed F Tavazoie (contact PI), Sohail F. Tavazoie

      $532,716

      award amount

15. Anum Azam Glasgow

    Leads 2 awards · $526,415

    • 1R35GM157185-01Department: NIH department code

      Mechanism-informed design of allosteric protein sensors
      $287,488

      award amount
    • 5R21EB035208-02Department: NIH department code

      Computationally designed, small molecule-responsive cell receptors for treating solid tumors
      $238,927

      award amount

16. Anna-Lena Steckelberg

    Leads 1 award · $411,250

    • 5R35GM150778-03Department: NIH department code

      Understanding the antiviral roles of acellular RNA quality control pathway
      $411,250

      award amount

17. Ya-Cheng Liao

    Leads 1 award · $411,250

    • 1R35GM157319-01Department: NIH department code

      Dissecting the molecular composition and function of contact between membrane-bound and membrane-less organelles
      $411,250

      award amount

18. Yufeng Shen

    Leads 1 award · $406,912

    • 5R35GM149527-03Department: NIH department code

      Computational methods to interpret genomic variation and integrate functional genomics data in genetic analysis of human diseases
      $406,912

      award amount

19. Naomi Latorraca

    Leads 1 award · $249,000

    • 4R00GM148823-03Department: NIH department code

      Decoding Structural Determinants of Efficacy and Specificity in a GPCR Subfamily
      $249,000

      award amount

20. Jaeseung Hahn

    Leads 1 award · $172,044

    • 5K99CA283259-02Department: NIH department code

      Programmable biohybrid system for cancer therapy
      $172,044

      award amount

21. Sahiti Kuppa

    Leads 1 award · $96,243

    • 5K00CA274696-04Department: NIH department code

      Role of nuclear chaperones in genomic instability and carcinogenesis
      $96,243

      award amount

22. Rebeca Teresa King

    Leads 1 award · $54,538

    • 5F31HL167530-03Department: NIH department code

      Leveraging CRISPR RNA-guided DNA Transposases for Gene Insertion at the CFTR Locus
      $54,538

      award amount

23. Stephen Tang

    Leads 1 award · $52,040

    • 5F30AI183830-02Department: NIH department code

      Mechanisms of reverse transcriptase mediated phage resistance in Enterobacteriaceae
      $52,040

      award amount

24. Tiberiu Mihaila

    Leads 1 award · $51,492

    • 1F30DC022796-01Department: NIH department code

      Disentangling the roles of endoplasmic reticulum stress and activity in the peripheral olfactory circuit
      $51,492

      award amount

25. Belen Sundberg

    Leads 1 award · $49,538

    • 5F31AI184134-02Department: NIH department code

      Elucidating the complex allosteric regulation of PFK-1, a broadly evolutionarily conserved glycolytic enzyme
      $49,538

      award amount

26. Thomas Payne Newton

    Leads 1 award · $49,538

    • 1F31NS147755-01Department: NIH department code

      Structure Determination of Heterologous and Native AMPA Receptors and their Complexes with Auxiliary Subunits
      $49,538

      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.

• Daniel Herschlag

  Co-investigator on 5R01AI178848-03, led by Hashim M Al-Hashimi

  From the FY2025 awards this person leads

  • Stanford University · Biochemistry (NIH department code, 1 award)

• Stephen Paine Goff

  Co-investigator on 5R01AI178848-03, led by Hashim M Al-Hashimi

  From the FY2024 awards this person leads

  • Columbia University · Biochemistry (NIH department code, 1 award)

• Sohail F. Tavazoie

  Co-investigator on 5R01CA257153-05, led by Saeed F Tavazoie

  From the FY2025 awards this person leads

  • Rockefeller University · Biology (NIH department code, 1 award)
  • Rockefeller University (no department on record, 1 award)

• Peter Alan Sims

  Co-investigator on 1T32GM158494-01, led by Chaolin Zhang

  From the FY2025 awards this person leads

  • Columbia University (no department on record, 4 awards)