Biochemistry at Columbia University

Leads a grant in this department

36 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Leong, Kam W

   Leads 2 awards · $1,955,674

   • 5UH3TR002151-04Department: NIH department code

     Integrated Microphysiological System of Cerebral Organoid and Blood Vessel for Disease Modeling and Neuropsychiatric Drug screening
     $1,189,483

     award amount
   • 5UG3NS115598-03Department: NIH department code

     Focused Ultrasound-mediated Delivery of Gene-editing Elements to the Brain for Neurodegenerative Disorders
     $766,191

     award amount

2. Tavazoie, Saeed F

   Leads 4 awards · $1,698,447

   • 1R01CA257153-01Department: NIH department code

     Mapping the regulatory landscape of RNA binding proteins and their causal roles in tumorigenesis and patient survival
     $562,675

     award amount
   • 5R01AI077562-12Department: NIH department code

     Systems biological interrogation of bacterial persistence
     $530,830

     award amount
   • 5R01GM139215-02Department: NIH department code

     Stochastic tuning: a novel regulatory mechanism for cellular adaptation
     $402,442

     award amount
   • 1R21AI157298-01Department: NIH department code

     Single-cell characterization of antibiotic-induced heteroresistance
     $202,500

     award amount

3. Fitzpatrick, Anthony William Paul

   Leads 1 award · $1,629,162

   • 5U01NS110438-04Department: NIH department code

     Patient-Based Structural Biology of Tauopathies and TDP-43 Proteinopathies using Cryo-Electron Microscopy and Mass Spectrometry
     $1,629,162

     award amount

4. Lomvardas, Stavros

   Leads 3 awards · $1,561,981

   • 5U01DA052783-02Department: NIH department code

     Interrogating genome folding trajectories in health and disease
     $622,658

     award amount
   • 5R01DC018744-02Department: NIH department code

     Olfactory receptor mRNAs as lncRNAs that regulate genomic interactions
     $480,534

     award amount
   • 5R01DC018745-02Department: NIH department code

     Principles of zonal olfactory receptor gene expression
     $458,789

     award amount

5. Greene, Eric C

   Leads 4 awards · $1,370,058

   • 2R35GM118026-06Department: NIH department code

     Mechanisms of Genome Integrity
     $551,971

     award amount
   • 5R01CA236606-03Department: NIH department code

     Helicase regulation during homologous recombination
     $370,575

     award amount
   • 5R01CA221858-02Department: NIH department code

     Defining the contributions of BRCA1, BRCA2, and RAD52 to genome stability
     $354,110

     award amount
   • 3R35GM118026-06S1Department: NIH department code

     Protein purification instrumentation in support of single molecule studies of genome integrity
     $93,402

     award amount

6. Maniatis, Thomas P

   Leads 2 awards · $1,137,680

   • 2R01MH108579-06A1Department: NIH department code

     The role of the clustered protocadherins in neural circuit formation and implications for neurodevelopmental disorders
     $657,586

     award amount
   • 5R01MH114817-09Department: NIH department code

     The structural basis of cis and trans protocadherin interactions
     $480,094

     award amount

7. Vitkup, Dennis

   Leads 2 awards · $1,116,646

   • 5R01DK118044-04Department: NIH department code

     Ecological dynamics and metabolic interactions in thegut microbiome across space and time
     $677,285

     award amount
   • 5R35GM131884-03Department: NIH department code

     Systems Biology of Protein and Phenotypic Evolution
     $439,361

     award amount

8. Mann, Richard S

   Leads 2 awards · $1,092,101

   • 2R35GM118336-06Department: NIH department code

     Interpreting and Deploying Genomic Information During Animal Development
     $630,577

     award amount
   • 5R01NS070644-12Department: NIH department code

     Development and function of an adult locomotion circuit in Drosophila
     $461,524

     award amount

9. Zhang, Chaolin

   Leads 2 awards · $958,352

   • 1R01GM136856-01A1Department: NIH department code

     Integrative analysis of tissue-specific alternative splicing regulation under adaptive selection
     $516,697

     award amount
   • 5R01GM124486-04Department: NIH department code

     Single-nucleotide resolution mapping of allelic protein-RNA interactions and splicing-regulatory variants
     $441,655

     award amount

10. Bussemaker, Harmen J

    Leads 1 award · $776,594

    • 5R01MH106842-05Department: NIH department code

      Integrative analysis of genetic variation and transcription factor networks to elucidate mechanisms of mental health disorders
      $776,594

      award amount

11. Gogos, Joseph A

    Leads 1 award · $760,468

    • 5R01MH124923-02Department: NIH department code

      Discovery and analysis of brain circuits and cell types affected in autism and schizophrenia
      $760,468

      award amount

12. Sobolevsky, Alexander

    Leads 2 awards · $757,787

    • 5R01CA206573-05Department: NIH department code

      Structure and function of Transient Receptor Potential channels
      $383,699

      award amount
    • 5R01NS107253-04Department: NIH department code

      Single-particle cryo-EM characterization of AMPA receptor functional states
      $374,088

      award amount

13. Landweber, Laura F

    Leads 1 award · $724,888

    • 5R35GM122555-05Department: NIH department code

      Understanding Complex Gene Editing Systems and RNA Biology in Oxytricha
      $724,888

      award amount

14. Goff, Stephen Paine

    Leads 2 awards · $709,522

    • 5R01CA030488-40Department: NIH department code

      Mechanisms of Silencing of Retroviral DNAs in Embryonic Cell Lines
      $466,522

      award amount
    • 5R21AI150813-02Department: NIH department code

      Role of heme oxygenase 2 in trafficking and regulation of myristoylated proteins
      $243,000

      award amount

15. Korem, Tal

    Leads 1 award · $695,238

    • 1R01HD106017-01Department: NIH department code

      A large scale investigation of the vaginal metagenome and metabolome and their role in spontaneous preterm birth
      $695,238

      award amount

16. Sternberg, Samuel Henry

    Leads 1 award · $688,498

    • 1R01EB031935-01Department: NIH department code

      A high-performance and versatile technology for precision microbiome engineering
      $688,498

      award amount

17. Mueller, Ulrich

    Leads 1 award · $647,665

    • 5R01DC016960-04Department: NIH department code

      Integrative Structural and Functional Characterization of Tip-Link Cadherins Deafness
      $647,665

      award amount

18. Frank, Joachim

    Leads 1 award · $640,351

    • 1R35GM139453-01Department: NIH department code

      Structural Studies of Macromolecular Assemblies Using Cryo-EM
      $640,351

      award amount

19. Barasch, Jonathan M.

    Leads 1 award · $631,377

    • 5R01DK124667-02Department: NIH department code

      Structure and mechanism of the protein-capture receptors of the kidney proximal tubule
      $631,377

      award amount

20. Wang, Harris H

    Leads 1 award · $611,597

    • 5R01AI132403-05Department: NIH department code

      Micron-scale Spatial Metagenomic Mapping of Microbial Biogeography in the Gastrointestinal Tract
      $611,597

      award amount

21. Palmer, Arthur G

    Leads 1 award · $559,114

    • 5R35GM130398-03Department: NIH department code

      Macromolecular dynamics and conformational changes in biological function
      $559,114

      award amount

22. Kurnikova, Maria G

    Leads 1 award · $501,283

    • 5R01NS083660-09Department: NIH department code

      Structure and Function of AMPA subtype ionotropic glutamate receptors
      $501,283

      award amount

23. Shapiro, Lawrence S

    Leads 1 award · $477,355

    • 5R01AR073846-04Department: NIH department code

      Structure and mechanism of pemphigus autoantibodies
      $477,355

      award amount

24. Hendrickson, Wayne A.

    Leads 1 award · $396,857

    • 5R01GM107462-08Department: NIH department code

      Atomic Level Analysis of Biomolecular Structure
      $396,857

      award amount

25. Sia, Samuel K

    Leads 1 award · $392,798

    • 5R01HL141935-04Department: NIH department code

      Injectable microtissues to promote rapid host re-perfusion of ischemic tissues
      $392,798

      award amount

26. Shen, Yufeng

    Leads 1 award · $333,146

    • 5R01GM120609-05Department: NIH department code

      Integrate cancer genomics data in genetic studies and diagnosis of developmental disorders
      $333,146

      award amount

27. Rubin, Mishaela R

    Leads 1 award · $283,500

    • 1R01DK126479-01A1Department: NIH department code

      Continuous calcium sensor patch for hypoparathyroid patients
      $283,500

      award amount

28. Duffie, Rachel

    Leads 1 award · $162,000

    • 5R21DC017823-03Department: NIH department code

      Translational control of sensory identity
      $162,000

      award amount

29. Campbell, Melissa McKenzie

    Leads 1 award · $109,935

    • 1K99MH126430-01Department: NIH department code

      mRNA Alternative Splicing Regulatory Networks in the Specification of Cortical Interneuron Subtypes
      $109,935

      award amount

30. Zamurrad, Sumaira

    Leads 2 awards · $76,390

    • 5F32MH123012-02Department: NIH department code

      Mapping the neural circuitry underlying walking
      $73,890

      award amount
    • 3F32MH123012-01S1Department: NIH department code

      Mapping the neural circuitry underlying walking
      $2,500

      award amount

31. Hobson, Benjamin

    Leads 1 award · $51,036

    • 5F30DA047775-03Department: NIH department code

      Gene Expression Programs in Maturing Dopamine Neurons: Temporal Regulation, Subcellular Localization, and Alteration by Amphetamine
      $51,036

      award amount

32. Tuddenham, John

    Leads 1 award · $51,036

    • 1F30CA261090-01Department: NIH department code

      Elucidating transcriptomic and functional heterogeneity of microglia in low-grade glioma and glioma-associated epilepsy.
      $51,036

      award amount

33. Martorella, Molly

    Leads 1 award · $46,521

    • 5F30HG011194-02Department: NIH department code

      Experimental and Computational Methods for Scaling-up Transcriptome Analyses and Improving Disease Risk Predictions
      $46,521

      award amount

34. Shayya, Hani John

    Leads 1 award · $46,521

    • 5F30DC019263-02Department: NIH department code

      The unfolded protein response as a mechanism for cellular identity in the developing olfactory system
      $46,521

      award amount

35. Akinade, Tolulope Olatokunbo

    Leads 1 award · $46,036

    • 1F31CA257399-01Department: NIH department code

      Design and Application of Cationic Nanocarriers to Inhibit Breast Cancer Progression in Primary and Metastatic Sites
      $46,036

      award amount

36. Flynn, Elise Duboscq

    Leads 1 award · $37,424

    • 5F31HG010580-02Department: NIH department code

      Investigating the role of transcription factors in the context variability of genetic variant effects
      $37,424

      award amount