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FY2026 NIH awards · Principal investigators

Biochemistry at University of California-Irvine

Irvine, CA

Funding
$20.8M
$20,789,931
Awards
46
FY2026 NIH awards in Biochemistry
Principal investigators
44
32 lead a grant here, 12 co-investigators
Department rank
#9
of 136 · Ranking
  • NIH names only the principal investigators on an award, so this page lists only them. The department is the award's: it is where ScienceDex counts the award, not a list of the department's members.
  • These are the awards in the Biochemistry row of the University of California-Irvine page.

Leads a grant in this department

32 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

  1. Ivan Marazzi

    Leads 3 awards · $3,219,438

    • 5U54OD039864-02Department: NIH department code
      Center for Modeling Non-Coding Disease Variants

      Principal investigators: Changrui Xiao (contact PI), Evgeny Kvon (contact PI), Grant R MacGregor (contact PI), Ivan Marazzi (contact PI), Marcus Michael Seldin (contact PI)

      $1,834,108
      award amount
    • 5R01AI168130-05Department: NIH department code
      Regulation of inflammatory gene expression during SARS2 infection
      $747,848
      award amount
    • 5R01NS123287-04Department: NIH department code
      T cell Immunity in a Rare Juvenile Form of Motor Neuron Disease

      Principal investigators: Ivan Marazzi (contact PI), Laura Campisi

      $637,482
      award amount

  2. Changrui Xiao

    Leads 1 award · $1,834,108

  3. Evgeny Kvon

    Leads 1 award · $1,834,108

  4. Grant R MacGregor

    Leads 1 award · $1,834,108

  5. Marcus Michael Seldin

    Leads 1 award · $1,834,108

  6. Charles G. Glabe

    Leads 2 awards · $1,832,902

    • 5U24AG079683-05Department: NIH department code
      Shared resource to develop tools and reagents to study structural polymorphisms in Abeta amyloid aggregates in AD

      Principal investigators: Charles G. Glabe (contact PI), Elizabeth Head

      $1,089,279
      award amount
    • 5R01AG079185-03Department: NIH department code
      Temporal, Spatial and Cellular Dynamics of Amyloid Plaque Deposition
      $743,623
      award amount

  7. Christopher C. W. Hughes

    Leads 2 awards · $1,642,222

    • 4R01CA290115-03Department: NIH department code
      A vascularized microphysiological system (MPS) platform for modeling peritoneal carcinomatosis

      Principal investigators: Christopher C. W. Hughes (contact PI), Maheswari Senthil

      $1,563,722
      award amount
    • 5R03NS141038-02Department: NIH department code
      Repurposing drugs to treat Hereditary Hemorrhagic Telangiectasia: identification using a vascularized HHT on-a-chip microphysiological system platform
      $78,500
      award amount

  8. Peter Kaiser

    Leads 5 awards · $1,636,518

    • 5R35GM148350-04Department: NIH department code
      Ubiquitin and Metabolite Signaling
      $605,891
      award amount
    • 5R01CA283462-04Department: NIH department code
      Mechanisms of mutant p53 reactivation

      Principal investigators: Peter Kaiser (contact PI), Scott D. Rychnovsky

      $585,199
      award amount
    • 1R21CA307778-01Department: NIH department code
      Harnessing Nutritional Modulation to Enhance Cancer Drug Potency

      Principal investigators: Peter Kaiser (contact PI), Christopher J. Halbrook

      $403,686
      award amount
    • 3R35GM148350-04S2Department: NIH department code
      Ubiquitin and Metabolite Signaling
      $26,516
      award amount
    • 3R35GM148350-04S1Department: NIH department code
      Ubiquitin and Metabolite Signaling
      $15,226
      award amount

  9. Dequina Angelina Nicholas

    Leads 3 awards · $1,457,078

    • 5U01AI180164-03Department: NIH department code
      Impact of aging on human B cell vaccine responses

      Principal investigators: Dequina Angelina Nicholas (contact PI), Dorota Skowronska-Krawczyk, Lisa Wagar

      $565,200
      award amount
    • 5DP2AI171121-05Department: NIH department code
      Lipid Antigen Presentation as a Driver of T2D Inflammation
      $456,187
      award amount
    • 1R61HD123427-01Department: NIH department code
      Toll-Like Receptor 4 Antagonism for Infertility Management in Polycystic Ovary Syndrome

      Principal investigators: Dequina Angelina Nicholas (contact PI), Jessica Chan, Ulrike Luderer

      $435,691
      award amount

  10. Kai Kessenbrock

    Leads 1 award · $1,445,280

    • 4R01CA234496-08Department: NIH department code
      Microenvironmental regulation of breast tumorigenesis
      $1,445,280
      award amount

  11. Remi Buisson

    Leads 4 awards · $1,209,613

    • 1R01CA307676-01A1Department: NIH department code
      Mechanisms and Functional Roles of PARP1 Hyperactivation in Cancer
      $639,707
      award amount
    • 4R37CA252081-06Department: NIH department code
      Molecular Mechanisms of APOBEC-Induced Mutagenesis in Cancer
      $351,656
      award amount
    • 5R21AI185033-02Department: NIH department code
      Role of APOBEC3B in the Innate Immune Response
      $196,250
      award amount
    • 1R13CA317939-01Department: NIH department code
      2026 SoCal Genome Stability Symposium
      $22,000
      award amount

  12. Selma Masri

    Leads 2 awards · $1,092,566

    • 5R01CA244519-07Department: NIH department code
      Circadian Clock Disruption and Colorectal Cancer
      $588,619
      award amount
    • 5R01CA259370-05Department: NIH department code
      Circadian Clock and Myc-dependent Regulation of Cellular Transformation
      $503,947
      award amount

  13. Kyoko Yokomori

    Leads 2 awards · $707,573

  14. Ray Luo

    Leads 2 awards · $609,371

    • 5R35GM130367-07Department: NIH department code
      Multi-scaled Modeling of Electrostatic and Polarization Effects in Biomolecules
      $431,750
      award amount
    • 3R35GM130367-07S1Department: NIH department code
      Multi-scaled modeling of electrostatic and polarization effects in biomolecules
      $177,621
      award amount

  15. Yilin Hu

    Leads 1 award · $503,280

    • 1R35GM161208-01Department: NIH department code
      Nitrogenase - From mechanistic investigation to heterologous expression
      $503,280
      award amount

  16. Markus W Ribbe

    Leads 1 award · $487,953

    • 1R35GM161209-01Department: NIH department code
      Nitrogenase - Where Haber-Bosch meets Fischer-Tropsch
      $487,953
      award amount

  17. Nir Drayman

    Leads 1 award · $460,359

    • 5DP2AI154437-05Department: NIH department code
      Harnessing cell-to-cell variability to understand viral infection outcomes
      $460,359
      award amount

  18. Christopher J. Halbrook

    Leads 1 award · $446,746

    • 5R37CA283575-03Department: NIH department code
      Targeting Metabolic Crosstalk in Pancreatic Cancer
      $446,746
      award amount

    Also a principal investigator on 1R21CA307778-01, led by Peter Kaiser.

  19. Xing Dai

    Leads 1 award · $431,750

    • 5R35GM145307-05Department: NIH department code
      Intrinsic and extrinsic control of epithelial tissue stem cell activity
      $431,750
      award amount

  20. Feng Qiao

    Leads 1 award · $392,500

    • 5R35GM149572-04Department: NIH department code
      Molecular Mechanisms of Telomere Length Homeostasis
      $392,500
      award amount

  21. Vittorio Sebastiano

    Leads 1 award · $392,500

    • 7R01HL157139-05Department: NIH department code
      Dissecting the Molecular Role of TBX1 in the Context of Human Pharyngeal EndodermDevelopment
      $392,500
      award amount

  22. Mei Kong

    Leads 1 award · $383,902

    • 5R35GM153227-03Department: NIH department code
      Regulatory Mechanisms of PP2A Family Phosphatases
      $383,902
      award amount

  23. Benjamin Robert Morehouse

    Leads 1 award · $379,823

    • 5R35GM157311-02Department: NIH department code
      Defining the mechanisms that drive novel cyclic nucleotide signaling in immune defense
      $379,823
      award amount

  24. Melissa Bruckner Lodoen

    Leads 2 awards · $368,240

  25. Reginald McNulty

    Leads 1 award · $365,267

    • 1R35GM163899-01Department: NIH department code
      Macromolecular Structure and Mechanism of Innate Immune Complexes
      $365,267
      award amount

  26. Celia Goulding

    Leads 2 awards · $346,928

    • 1R21AI193989-01A1Department: NIH department code
      Discovery and preliminary characterization of proteins required for Mycobacterium tuberculosis heme degradation
      $205,216
      award amount
    • 1R21AI190954-01A1Department: NIH department code
      Characterization of a novel histidine phosphotransfer system involved in the virulence of Mycobacterium tuberculosis
      $141,712
      award amount

    Also a principal investigator on 5T32AI141346-07, led by Melissa Bruckner Lodoen.

  27. Michael T. Green

    Leads 1 award · $318,337

    • 5R01GM101390-11Department: NIH department code
      Thermodynamic, Electronic, Structural, and Kinetic Characterizations of Cytochrome P450 Compounds I & II
      $318,337
      award amount

  28. Ran Jing

    Leads 1 award · $249,000

    • 7R00HL170075-04Department: NIH department code
      Identification of Novel Epigenetic Regulators of lymphocyte Development
      $249,000
      award amount

  29. Paul D Gershon

    Leads 1 award · $235,500

    • 1R21AI196970-01Department: NIH department code
      Molecular Architecture of the Vaccinia virus factory
      $235,500
      award amount

  30. Miranda Louise Lopez

    Leads 1 award · $76,848

    • 1R36AG097777-01Department: NIH department code
      Unraveling the longitudinal effects of lifelong inulin supplementation on the metabolic pathophysiology of aging
      $76,848
      award amount

  31. Johnny Le

    Leads 1 award · $55,114

    • 5F31DK134173-04Department: NIH department code
      Elucidating the role of nonessential amino acid metabolism in diabetic skin wounds
      $55,114
      award amount

  32. Ian James Tamburini

    Leads 1 award · $43,323

    • 1F31HL182233-01A1Department: NIH department code
      Innate immune pathway activation in endothelial cells by circulating bile acids during atherosclerosis
      $43,323
      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.