Biochemistry at University of California-Irvine

Leads a grant in this department

31 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Roberto Tinoco

   Leads 1 award · $2,832,747

   • 1R01AI187458-01A1Department: NIH department code

     Metabolic Regulation by SAPS3 of Virus-specific T cell Immunity

     Principal investigators: Roberto Tinoco (contact PI), Mei Kong

     $2,832,747

     award amount

2. Charles G. Glabe

   Leads 2 awards · $1,823,416

   • 5U24AG079683-04Department: NIH department code

     Shared resource to develop tools and reagents to study structural polymorphisms in Abeta amyloid aggregates in AD

     Principal investigators: Charles G. Glabe (contact PI), Elizabeth Head

     $1,089,279

     award amount
   • 4R01AG079185-02Department: NIH department code

     Temporal, Spatial and Cellular Dynamics of Amyloid Plaque Deposition
     $734,137

     award amount

3. Ivan Marazzi

   Leads 2 awards · $1,363,155

   • 5R01AI168130-04Department: NIH department code

     Regulation of inflammatory gene expression during SARS2 infection
     $725,413

     award amount
   • 5R01NS123287-03Department: NIH department code

     T cell Immunity in a Rare Juvenile Form of Motor Neuron Disease

     Principal investigators: Ivan Marazzi (contact PI), Laura Campisi

     $637,742

     award amount

4. Peter Kaiser

   Leads 3 awards · $1,260,468

   • 5R35GM148350-03Department: NIH department code

     Ubiquitin and Metabolite Signaling
     $605,891

     award amount
   • 5R01CA283462-03Department: NIH department code

     Mechanisms of mutant p53 reactivation

     Principal investigators: Peter Kaiser (contact PI), Scott D. Rychnovsky

     $563,224

     award amount
   • 3R35GM148350-03S1Department: NIH department code

     Ubiquitin and Metabolite Signaling
     $91,353

     award amount

5. Selma Masri

   Leads 2 awards · $1,133,722

   • 5R01CA259370-04Department: NIH department code

     Circadian Clock and Myc-dependent Regulation of Cellular Transformation
     $571,805

     award amount
   • 2R01CA244519-06A1Department: NIH department code

     Circadian Clock Disruption and Colorectal Cancer
     $561,917

     award amount

6. Remi Buisson

   Leads 4 awards · $1,095,438

   • 1R21ES036190-01A1Department: NIH department code

     NF-KB regulation by the DNA damage response
     $431,750

     award amount
   • 5R37CA252081-05Department: NIH department code

     Molecular Mechanisms of APOBEC-Induced Mutagenesis in Cancer
     $337,605

     award amount
   • 1R21AI185033-01A1Department: NIH department code

     Role of APOBEC3B in the Innate Immune Response
     $228,435

     award amount
   • 3R37CA252081-05S1Department: NIH department code

     Molecular Mechanisms of APOBEC-Induced Mutagenesis in Cancer
     $97,648

     award amount

7. Dequina Angelina Nicholas

   Leads 2 awards · $1,025,092

   • 5U01AI180164-02Department: NIH department code

     Impact of aging on human B cell vaccine responses

     Principal investigators: Dequina Angelina Nicholas (contact PI), Dorota Skowronska-Krawczyk, Lisa Wagar

     $565,200

     award amount
   • 5DP2AI171121-04Department: NIH department code

     Lipid Antigen Presentation as a Driver of T2D Inflammation
     $459,892

     award amount

8. Mei Kong

   Leads 2 awards · $809,379

   • 5R01CA244360-05Department: NIH department code

     Using dietary glutamine supplementation for melanoma prevention and targeted therapy
     $424,991

     award amount
   • 5R35GM153227-02Department: NIH department code

     Regulatory Mechanisms of PP2A Family Phosphatases
     $384,388

     award amount

   Also a principal investigator on 1R01AI187458-01A1, led by Roberto Tinoco.

9. Paul D Gershon

   Leads 1 award · $738,091

   • 1S10OD038285-01Department: NIH department code

     From hybrid to Tribrid: A refurbished Orbitrap Eclipse Tribrid Mass Spectrometer
     $738,091

     award amount

10. Kyoko Yokomori

    Leads 2 awards · $725,684

    • 5R01AR071287-09Department: NIH department code

      Genetic and epigenetic mechanisms of FSHD pathogenesis

      Principal investigators: Kyoko Yokomori (contact PI), Seyed Ali Mortazavi

      $487,728

      award amount
    • 5T32AR083870-02Department: NIH department code

      MAXIMUS: MAXimizing Training in MUScle Research

      Principal investigators: Kyoko Yokomori (contact PI), Sergio Armando Villalta, Tahseen Mozaffar

      $237,956

      award amount

11. Marcus Michael Seldin

    Leads 2 awards · $659,233

    • 5DP1DK130640-05Department: NIH department code

      Integrative approaches to dissection of endocrine communication
      $618,000

      award amount
    • 3DP1DK130640-05S1Department: NIH department code

      Integrative approaches to dissection of endocrine communication
      $41,233

      award amount

12. Melissa Bruckner Lodoen

    Leads 3 awards · $614,242

    • 1R21AI189465-01A1Department: NIH department code

      Microglial immunity in Toxoplasmic encephalitis
      $227,018

      award amount
    • 2T32AI141346-06A1Department: NIH department code

      T32 for Training in Microbiology & Infectious Diseases

      Principal investigators: Melissa Bruckner Lodoen (contact PI), Celia Goulding, Jennifer Bellanca Hughes Martiny

      $198,924

      award amount
    • 5R21AI181315-02Department: NIH department code

      Role of TREM2 in host defense and immunity during infection
      $188,300

      award amount

13. Christopher C. W. Hughes

    Leads 2 awards · $599,740

    • 5R01CA290115-02Department: NIH department code

      A vascularized microphysiological system (MPS) platform for modeling peritoneal carcinomatosis

      Principal investigators: Christopher C. W. Hughes (contact PI), Maheswari Senthil

      $521,240

      award amount
    • 1R03NS141038-01Department: NIH department code

      Repurposing drugs to treat Hereditary Hemorrhagic Telangiectasia: identification using a vascularized HHT on-a-chip microphysiological system platform
      $78,500

      award amount

14. Irina F Sevrioukova

    Leads 1 award · $561,595

    • 5R01ES025767-09Department: NIH department code

      Toxicological importance of CYP3A4 catalysis and inhibition
      $561,595

      award amount

15. Kai Kessenbrock

    Leads 1 award · $481,760

    • 5R01CA234496-07Department: NIH department code

      Microenvironmental regulation of breast tumorigenesis
      $481,760

      award amount

16. Nir Drayman

    Leads 1 award · $460,359

    • 5DP2AI154437-04Department: NIH department code

      Harnessing cell-to-cell variability to understand viral infection outcomes
      $460,359

      award amount

17. Travis J Wiles

    Leads 2 awards · $453,453

    • 5DP2AI154420-05Department: NIH department code

      Connecting the Spatiotemporal Organization of Gut Bacterial Communities to the Emergence and Spread of Antibiotic Resistance
      $452,668

      award amount
    • 3DP2AI154420-05S1Department: NIH department code

      Connecting the Spatiotemporal Organization of Gut Bacterial Communities to the Emergence and Spread of Antibiotic Resistance
      $785

      award amount

18. Christopher J. Halbrook

    Leads 1 award · $445,319

    • 5R37CA283575-02Department: NIH department code

      Targeting Metabolic Crosstalk in Pancreatic Cancer
      $445,319

      award amount

19. Cholsoon Jang

    Leads 2 awards · $438,983

    • 5R01AA029124-05Department: NIH department code

      Elucidating dietary fructose and alcohol interactions during liver cancer development
      $353,250

      award amount
    • 3R01AA029124-05S1Department: NIH department code

      Elucidating dietary fructose and alcohol interactions during liver cancer development
      $85,733

      award amount

20. Ray Luo

    Leads 1 award · $431,750

    • 2R35GM130367-06Department: NIH department code

      Multi-scaled Modeling of Electrostatic and Polarization Effects in Biomolecules
      $431,750

      award amount

21. Xing Dai

    Leads 1 award · $431,750

    • 5R35GM145307-04Department: NIH department code

      Intrinsic and extrinsic control of epithelial tissue stem cell activity
      $431,750

      award amount

22. Feng Qiao

    Leads 1 award · $392,500

    • 5R35GM149572-03Department: NIH department code

      Molecular Mechanisms of Telomere Length Homeostasis
      $392,500

      award amount

23. Benjamin Robert Morehouse

    Leads 1 award · $379,823

    • 1R35GM157311-01Department: NIH department code

      Defining the mechanisms that drive novel cyclic nucleotide signaling in immune defense
      $379,823

      award amount

24. Shane Gonen

    Leads 1 award · $372,060

    • 5R35GM142797-05Department: NIH department code

      Breaking barriers in CryoEM through computational protein design
      $372,060

      award amount

    Also a principal investigator on 5R21AI185695-02, led by Celia Goulding.

25. Wei Li

    Leads 1 award · $360,307

    • 5R01CA193466-10Department: NIH department code

      Computational and Experimental Modeling of Alternative Polyadenylation
      $360,307

      award amount

26. David Alexander Fruman

    Leads 1 award · $333,547

    • 5T32CA009054-45Department: NIH department code

      A Training Program for Interdisciplinary Cancer Research

      Principal investigators: David Alexander Fruman (contact PI), Aimee L Edinger

      $333,547

      award amount

27. Michael T. Green

    Leads 1 award · $320,356

    • 2R01GM101390-10Department: NIH department code

      Thermodynamic, Electronic, Structural, and Kinetic Characterizations of Cytochrome P450 Compounds I & II
      $320,356

      award amount

28. Olga V Razorenova

    Leads 1 award · $209,646

    • 5R21CA280564-02Department: NIH department code

      Therapeutic targeting of VHL-deficient clear cell renal cell carcinoma
      $209,646

      award amount

29. Celia Goulding

    Leads 1 award · $187,188

    • 5R21AI185695-02Department: NIH department code

      Investigation of the interaction of Bordetella FhaB adhesin with microtubules

      Principal investigators: Celia Goulding (contact PI), Christopher S. Hayes, Shane Gonen

      $187,188

      award amount

    Also a principal investigator on 2T32AI141346-06A1, led by Melissa Bruckner Lodoen.

30. Johnny Le

    Leads 1 award · $54,538

    • 5F31DK134173-03Department: NIH department code

      Elucidating the role of nonessential amino acid metabolism in diabetic skin wounds
      $54,538

      award amount

31. Miranda Emiko Kelly

    Leads 1 award · $43,019

    • 1F31HL182220-01Department: NIH department code

      Identifying novel microproteins and protein translation mechanisms involved in the development of atherosclerosis
      $43,019

      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.

• Elizabeth Head

  Co-investigator on 5U24AG079683-04, led by Charles G. Glabe

  From the FY2025 awards this person leads

  • University of California-Irvine · Pathology (NIH department code, 3 awards)
  • University of California-Irvine (no department on record, 1 award)

• Laura Campisi

  Co-investigator on 5R01NS123287-03, led by Ivan Marazzi

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Dorota Skowronska-Krawczyk

  Co-investigator on 5U01AI180164-02, led by Dequina Angelina Nicholas

  From the FY2025 awards this person leads

  • University of California-Irvine · Ophthalmology (NIH department code, 2 awards)

• Lisa Wagar

  Co-investigator on 5U01AI180164-02, led by Dequina Angelina Nicholas

  From the FY2025 awards this person leads

  • University of California-Irvine · Physiology (NIH department code, 1 award)
  • Scripps Research Institute (no department on record, 1 award)

• Scott D. Rychnovsky

  Co-investigator on 5R01CA283462-03, led by Peter Kaiser

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Maheswari Senthil

  Co-investigator on 5R01CA290115-02, led by Christopher C. W. Hughes

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Seyed Ali Mortazavi

  Co-investigator on 5R01AR071287-09, led by Kyoko Yokomori

  From the FY2025 awards this person leads

  • University of California-Irvine · Anatomy & Cell Biology (NIH department code, 1 award)
  • University of California-Irvine (no department on record, 1 award)

• Aimee L Edinger

  Co-investigator on 5T32CA009054-45, led by David Alexander Fruman

  From the FY2025 awards this person leads

  • University of California-Irvine · Anatomy & Cell Biology (NIH department code, 2 awards)

• Sergio Armando Villalta

  Co-investigator on 5T32AR083870-02, led by Kyoko Yokomori

  From the FY2024 awards this person leads

  • University of California-Irvine · Physiology (NIH department code, 3 awards)

• Tahseen Mozaffar

  Co-investigator on 5T32AR083870-02, led by Kyoko Yokomori

  From the FY2025 awards this person leads

  • University of California-Irvine · Neurology (NIH department code, 1 award)

• Jennifer Bellanca Hughes Martiny

  Co-investigator on 2T32AI141346-06A1, led by Melissa Bruckner Lodoen

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Christopher S. Hayes

  Co-investigator on 5R21AI185695-02, led by Celia Goulding

  From the FY2025 awards this person leads

  • University of California Santa Barbara · Biochemistry (NIH department code, 2 awards)