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FY2025 NIH awards · Principal investigators

Anatomy & Cell Biology at University of California-Irvine

Irvine, CA

Funding
$33.2M
$33,244,519
Awards
54
FY2025 NIH awards in Anatomy & Cell Biology
Principal investigators
52
32 lead a grant here, 20 co-investigators
Department rank
#2
of 82 · Ranking
  • NIH names only the principal investigators on an award, so this page lists only them. The department is the award's: it is where ScienceDex counts the award, not a list of the department's members.
  • These are the awards in the Anatomy & Cell Biology row of the University of California-Irvine page.

Leads a grant in this department

32 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

  1. Xiangmin Xu

    Leads 8 awards · $9,346,016

    • 5U01AG076791-04Department: NIH department code
      Cell-type-specific neural circuit connectomes in the mouse models of aging and Alzheimer's disease

      Principal investigators: Xiangmin Xu (contact PI), Eran A Mukamel, Kim Green, Wei Xu

      $2,591,567
      award amount
    • 1R61AG094609-01Department: NIH department code
      Enhancer AAV-based genetic access and manipulation of specific brain cell types implicated in aging and Alzheimer's Disease
      $2,220,145
      award amount
    • 5R01AG082127-03Department: NIH department code
      Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regions

      Principal investigators: Xiangmin Xu (contact PI), Bing Ren, Michael D Koob

      $1,979,459
      award amount
    • 5U24MH133236-03Department: NIH department code
      UC Irvine Center for the production and distribution of cell-type-specific viral targeting reagents

      Principal investigators: Xiangmin Xu (contact PI), Gordon J Fishell

      $945,779
      award amount
    • 1R01AG092453-01Department: NIH department code
      Cell-type-specific and spatial proteogenomics analysis of aberrant RNA splicing and misfolded proteins in Alzheimer's related tauopathies

      Principal investigators: Xiangmin Xu (contact PI), Bogdan Bintu, Charles G. Glabe

      $773,816
      award amount
    • 5R01NS121246-05Department: NIH department code
      Neural activity-dependent modulation of cortical microvascular restoration

      Principal investigators: Xiangmin Xu (contact PI), Andre Obenaus

      $540,469
      award amount
    • 5T32AG081185-02Department: NIH department code
      The UC Irvine Center for Neural Circuit Mapping training program in Alzheimer's disease research

      Principal investigators: Xiangmin Xu (contact PI), Todd C Holmes

      $274,781
      award amount
    • 1R13MH139291-01Department: NIH department code
      UC Irvine Center for Neural Circuit Mapping 2025 Conference: The Changing Brain
      $20,000
      award amount

  2. Michael A Yassa

    Leads 6 awards · $3,824,277

    • 5R01AG053555-08Department: NIH department code
      Assessing the role of cerebrovascular brain injury and dysfunction in Alzheimer’s disease pathogenesis in the BEACoN Cohort
      $2,493,770
      award amount
    • 5R01MH128306-03Department: NIH department code
      Testing a Memory-Based Hypothesis for Anhedonia

      Principal investigators: Michael A Yassa (contact PI), Julian F. Thayer

      $742,709
      award amount
    • 5R25GM146300-04Department: NIH department code
      The Brain Explorer Academy (BEA): An Informal Science Education Partnership

      Principal investigators: Michael A Yassa (contact PI), Manuella Yassa

      $253,790
      award amount
    • 5T32MH119049-07Department: NIH department code
      Howard Schneiderman Training Program in Learning and Memory

      Principal investigators: Michael A Yassa (contact PI), Bruce L McNaughton, Manuella Yassa

      $169,624
      award amount
    • 3R01AG053555-08S1Department: NIH department code
      Assessing the role of cerebrovascular brain injury and dysfunction in Alzheimer’s disease pathogenesis in the BEACoN Cohort
      $82,192
      award amount
    • 3R01MH128306-03S1Department: NIH department code
      Testing a Memory-Based Hypothesis for Anhedonia

      Principal investigators: Michael A Yassa (contact PI), Julian F. Thayer

      $82,192
      award amount

  3. Kei M Igarashi

    Leads 3 awards · $3,643,948

    • 1RF1AG091584-01A1Department: NIH department code
      Circuit vulnerability of the lateral and medial entorhinal cortices in tauopathy models of Alzheimer's disease
      $2,489,452
      award amount
    • 1R01MH137156-01A1Department: NIH department code
      Understanding output circuits of the lateral entorhinal cortex
      $625,108
      award amount
    • 5R01AG086441-02Department: NIH department code
      Lateral entorhinal cortex dysfunction in an APP knock-in model of Alzheimer's disease
      $529,388
      award amount

  4. Thomas F Schilling

    Leads 3 awards · $2,764,004

    • 2R01DE013828-21Department: NIH department code
      Role and Regulation of Cellular Polarity in Craniofacial Skeletogenesis
      $1,845,189
      award amount
    • 5R01DE030565-05Department: NIH department code
      Dissecting single cell dynamics that coordinate neural crest migration and diversification

      Principal investigators: Thomas F Schilling (contact PI), Qing Nie

      $552,433
      award amount
    • 5R01AR067797-09Department: NIH department code
      Developmental regulation of cranial tendon fibroblast diversity and ECM interactions
      $366,382
      award amount

  5. Seyed Ali Mortazavi

    Leads 1 award · $2,483,575

    • 5UM1HG012077-05Department: NIH department code
      Center for Mouse Genomic Variation at Single Cell Resolution

      Principal investigators: Seyed Ali Mortazavi (contact PI), Barbara J Wold

      $2,483,575
      award amount

  6. Robert F Hunt

    Leads 3 awards · $1,396,507

    • 1R01NS137630-01A1Department: NIH department code
      Targeting synaptic dysfunction in lissencephaly

      Principal investigators: Robert F Hunt (contact PI), Lulu Yiju Chen

      $488,507
      award amount
    • 5R01NS126399-03Department: NIH department code
      Bidirectional control of Chd2 haploinsufficiency
      $483,456
      award amount
    • 5R01NS096012-10Department: NIH department code
      Rewiring the Injured Brain with GABA Progenitors
      $424,544
      award amount

    Also a principal investigator on 5T32NS045540-22, led by Tallie Z. Baram.

  7. Evgeny Kvon

    Leads 2 awards · $1,346,190

    • 4DP2GM149555-02Department: NIH department code
      Deciphering the mechanism of long-range gene regulation in vivo
      $942,000
      award amount
    • 5R01HD115268-02Department: NIH department code
      Decoding the Mechanism of Pathogenic Enhancer Mutations In Congenital Limb Disorders
      $404,190
      award amount

  8. Xiaoyu Shi

    Leads 1 award · $933,009

    • 4DP2GM150017-02Department: NIH department code
      Gel-based Optical-isolation Single-Cell 3D Spatial Multiomics
      $933,009
      award amount

  9. Aimee L Edinger

    Leads 2 awards · $714,886

    • 1R21TR005645-01Department: NIH department code
      Accelerating the translation of oligonucleotide therapeutics by enhancing delivery
      $419,398
      award amount
    • 5R01CA254360-05Department: NIH department code
      A novel strategy to overcome drug resistance in cancer
      $295,488
      award amount

  10. Wenqi Wang

    Leads 2 awards · $626,685

    • 5R01GM126048-08Department: NIH department code
      Regulation and function of the Hippo pathway in growth control
      $323,420
      award amount
    • 5R01GM143233-04Department: NIH department code
      Interplay of heavy metal homeostasis and cell growth-related signaling networks

      Principal investigators: Wenqi Wang (contact PI), Rahul Warrior

      $303,265
      award amount

  11. David C Lyon

    Leads 1 award · $575,017

    • 5R01EY032948-04Department: NIH department code
      Retinal sheet transplant impact on functional organization of visual cortex in retinal degenerate animal models

      Principal investigators: David C Lyon (contact PI), Magdalene J Seiler

      $575,017
      award amount

  12. Daniele Piomelli

    Leads 1 award · $541,998

    • 5R01DA055578-03Department: NIH department code
      The lipid hydrolase NAAA as a target for non-addictive analgesic medications
      $541,998
      award amount

  13. Maksim V Plikus

    Leads 1 award · $531,355

    • 5R01AR079150-04Department: NIH department code
      Tissue Size and Precision Control in Growing Hair Follicles

      Principal investigators: Maksim V Plikus (contact PI), Qing Nie

      $531,355
      award amount

  14. Christine M Gall

    Leads 2 awards · $526,073

    • 5R01HD101642-05Department: NIH department code
      Postnatal Oxytocin Treatment and Cognitive Function in Fragile X

      Principal investigators: Christine M Gall (contact PI), Gary S Lynch

      $443,855
      award amount
    • 3R01HD101642-05S1Department: NIH department code
      Postnatal Oxytocin Treatment and Cognitive Function in Fragile X

      Principal investigators: Christine M Gall (contact PI), Gary S Lynch

      $82,218
      award amount

  15. Arthur D Lander

    Leads 1 award · $505,410

    • 2T32GM136624-06Department: NIH department code
      Mathematical, Computational and Systems Biology

      Principal investigators: Arthur D Lander (contact PI), Qing Nie

      $505,410
      award amount

  16. Bruce Blumberg

    Leads 1 award · $460,781

    • 5R01ES031139-05Department: NIH department code
      Interactions between prenatal obesogen exposure and Total Western diet lead to a transgenerational thrifty phenotype: functional and epigenomic analysis of effects in fat and liver

      Principal investigators: Bruce Blumberg (contact PI), Toshihiro Shioda

      $460,781
      award amount

  17. Ken W.y. Cho

    Leads 1 award · $409,763

    • 5R35GM139617-05Department: NIH department code
      Maternal transcription factors shaping early embryonic chromatin landscape
      $409,763
      award amount

  18. Laura Ewell

    Leads 1 award · $392,500

    • 5R01NS128222-03Department: NIH department code
      Determining the shared neuronal network mechanisms of focal epileptic discharges and impaired memory processing in temporal lobe epilepsy
      $392,500
      award amount

  19. Pablo Andres Lara-Gonzalez

    Leads 1 award · $381,220

    • 5R35GM150786-03Department: NIH department code
      Developmental regulation of the cell cycle machinery
      $381,220
      award amount

  20. Dae Seok Eom

    Leads 1 award · $378,822

    • 5R35GM142791-05Department: NIH department code
      Signaling at a distance mediated by vesicles on novel cellular protrusions
      $378,822
      award amount

  21. Sha Sun

    Leads 1 award · $317,887

    • 5R01GM141424-05Department: NIH department code
      Elucidating the molecular basis of lncRNA evolution for mammalian dosage compensation
      $317,887
      award amount

    Also a principal investigator on 1R01HG014004-01, led by Hu Cang.

  22. Tallie Z. Baram

    Leads 1 award · $306,570

    • 5T32NS045540-22Department: NIH department code
      Epilepsy Research Training Program

      Principal investigators: Tallie Z. Baram (contact PI), Robert F Hunt

      $306,570
      award amount

  23. Hu Cang

    Leads 1 award · $289,900

    • 1R01HG014004-01Department: NIH department code
      Smart Laser Capturing Microscope for Genome Wide Single Cell Spatial Transcriptomics

      Principal investigators: Hu Cang (contact PI), Sha Sun

      $289,900
      award amount

  24. Alex Mabou Tagne

    Leads 1 award · $169,388

    • 1K01DK143205-01Department: NIH department code
      FAAH-regulated endocannabinoid signaling controls nociception in acute pancreatitis
      $169,388
      award amount

  25. Cassandra Leigh Kooiker

    Leads 1 award · $54,538

    • 5F30MH126615-04Department: NIH department code
      The thalamic paraventricular nucleus mediates the influence of early-life adversity on reward-seeking behaviors
      $54,538
      award amount

  26. Joshua Andrei Alcantara

    Leads 1 award · $46,770

    • 1F31HD118819-01Department: NIH department code
      Dissecting how gene regulatory redundancy ensures robustness of mammalian development
      $46,770
      award amount

  27. Grace Cabot Bower

    Leads 1 award · $46,705

    • 5F31HD112201-03Department: NIH department code
      Characterizing a mechanism of enhancer-promoter interaction in vivo
      $46,705
      award amount

  28. Ethan W Hollingsworth

    Leads 1 award · $46,427

    • 5F30HD110233-03Department: NIH department code
      Deciphering Mechanisms of Limb Malformations Caused by Noncoding Variants In Vivo
      $46,427
      award amount

  29. Chenyi Yang

    Leads 1 award · $46,127

    • 1F30MH135688-01A1Department: NIH department code
      Hippocampal network mediating behavioral effects of social isolation in mice
      $46,127
      award amount

  30. Gregory De Carvalho

    Leads 1 award · $46,127

    • 5F31MH138115-02Department: NIH department code
      The Impact of Early Life Adversity on mGluR5-driven Endocannabinoid Signaling and Behavioral Adaptability
      $46,127
      award amount

  31. Alexa Marie Tierno

    Leads 1 award · $46,022

    • 5F31NS132447-03Department: NIH department code
      Imaging progressive circuit reorganization after traumatic brain injury
      $46,022
      award amount

  32. Bernardo Maximiliano Garduno

    Leads 1 award · $46,022

    • 5F31AG082485-02Department: NIH department code
      Neuropathological and spatial transcriptome brain maps in Octodon degus, a natural Alzheimer's disease rodent model
      $46,022
      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.