Anatomy & Cell Biology at University of California-Irvine

Leads a grant in this department

29 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Xiangmin Xu

   Leads 10 awards · $9,847,923

   • 5U01AG076791-03Department: NIH department code

     Cell-type-specific neural circuit connectomes in the mouse models of aging and Alzheimer's disease

     Principal investigators: Xiangmin Xu (contact PI), Eran A Mukamel, Kim Green, Wei Xu

     $2,650,917

     award amount
   • 5R01AG082127-02Department: NIH department code

     Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regions

     Principal investigators: Xiangmin Xu (contact PI), Bing Ren, Michael D Koob

     $2,019,855

     award amount
   • 5R24AG073198-04Department: NIH department code

     Comparative Single-Cell Epigenomic Analysis of AD-like Pathogenesis in Unconventional Animal Models

     Principal investigators: Xiangmin Xu (contact PI), Bing Ren

     $1,177,566

     award amount
   • 5U24MH133236-02Department: NIH department code

     UC Irvine Center for the production and distribution of cell-type-specific viral targeting reagents

     Principal investigators: Xiangmin Xu (contact PI), Gordon J Fishell

     $992,170

     award amount
   • 5R01AG067153-05Department: NIH department code

     Epigenomic analysis of neural circuits in Alzheimer's disease mouse models

     Principal investigators: Xiangmin Xu (contact PI), Bing Ren

     $738,680

     award amount
   • 5U01DA052769-05Department: NIH department code

     Single-Cell Analysis of Aging-Associated 4D Nucleome in the Human Hippocampus

     Principal investigators: Xiangmin Xu (contact PI), Bing Ren

     $595,448

     award amount
   • 5R01NS121246-04Department: NIH department code

     Neural activity-dependent modulation of cortical microvascular restoration

     Principal investigators: Xiangmin Xu (contact PI), Andre Obenaus

     $531,129

     award amount
   • 4R01AG065675-02Department: NIH department code

     Neural circuit mechanisms underlying AD-related memory impairments
     $480,320

     award amount
   • 3U01DA052769-04S1Department: NIH department code

     Single-cell analysis of aging-associated 4D nucleome in the human hippocampus

     Principal investigators: Xiangmin Xu (contact PI), Bing Ren

     $382,100

     award amount
   • 1T32AG081185-01A1Department: NIH department code

     The UC Irvine Center for Neural Circuit Mapping training program in Alzheimer's disease research

     Principal investigators: Xiangmin Xu (contact PI), Todd C Holmes

     $279,738

     award amount

2. Michael A Yassa

   Leads 6 awards · $3,894,627

   • 5R01AG053555-07Department: NIH department code

     Assessing the role of cerebrovascular brain injury and dysfunction in Alzheimer’s disease pathogenesis in the BEACoN Cohort
     $2,544,663

     award amount
   • 5R01MH128306-02Department: NIH department code

     Testing a Memory-Based Hypothesis for Anhedonia

     Principal investigators: Michael A Yassa (contact PI), Julian F. Thayer

     $767,246

     award amount
   • 5R25GM146300-03Department: NIH department code

     The Brain Explorer Academy (BEA): An Informal Science Education Partnership

     Principal investigators: Michael A Yassa (contact PI), Nancy G. Guerra

     $256,243

     award amount
   • 2T32MH119049-06Department: NIH department code

     Howard Schneiderman Training Program in Learning and Memory

     Principal investigators: Michael A Yassa (contact PI), Bruce L McNaughton, Manuella Yassa

     $197,372

     award amount
   • 3R01AG053555-07S1Department: NIH department code

     Assessing the role of cerebrovascular brain injury and dysfunction in Alzheimer’s disease pathogenesis in the BEACoN Cohort
     $70,456

     award amount
   • 3R01MH128306-02S1Department: NIH department code

     Testing a Memory-Based Hypothesis for Anhedonia

     Principal investigators: Michael A Yassa (contact PI), Julian F. Thayer

     $58,647

     award amount

3. Seyed Ali Mortazavi

   Leads 1 award · $2,483,575

   • 5UM1HG012077-04Department: NIH department code

     Center for Mouse Genomic Variation at Single Cell Resolution

     Principal investigators: Seyed Ali Mortazavi (contact PI), Barbara J Wold

     $2,483,575

     award amount

4. Christine Suetterlin

   Leads 2 awards · $1,208,720

   • 5R01AI151212-05Department: NIH department code

     Mechanism of RB-to-EB Conversion in Chlamydia

     Principal investigators: Christine Suetterlin (contact PI), Daniela Boassa, German Andres Enciso, Ming Tan

     $688,445

     award amount
   • 5R01AI153410-05Department: NIH department code

     Primary cilia loss and cell cycle re-entry in Chlamydia-infected cells

     Principal investigators: Christine Suetterlin (contact PI), Ming Tan

     $520,275

     award amount

5. Daniele Piomelli

   Leads 2 awards · $1,152,188

   • 5R01DA055578-02Department: NIH department code

     The lipid hydrolase NAAA as a target for non-addictive analgesic medications
     $576,282

     award amount
   • 4R01AG065329-02Department: NIH department code

     The lipid amidase NAAA as a therapeutic target for Alzheimer's disease

     Principal investigators: Daniele Piomelli (contact PI), Kim Green

     $575,906

     award amount

6. Robert F Hunt

   Leads 2 awards · $941,599

   • 5R01NS126399-02Department: NIH department code

     Bidirectional control of Chd2 haploinsufficiency
     $521,059

     award amount
   • 5R01NS096012-09Department: NIH department code

     Rewiring the Injured Brain with GABA Progenitors
     $420,540

     award amount

   Also a principal investigator on 2T32NS045540-21, led by Tallie Z. Baram.

7. Kei M Igarashi

   Leads 2 awards · $932,691

   • 1R01AG086441-01Department: NIH department code

     Lateral entorhinal cortex dysfunction in an APP knock-in model of Alzheimer's disease
     $540,191

     award amount
   • 5R01AG066806-05Department: NIH department code

     Cell-type-specific vulnerability of the entorhinal cortex in Alzheimer's disease
     $392,500

     award amount

8. Thomas F Schilling

   Leads 2 awards · $907,767

   • 5R01DE030565-04Department: NIH department code

     Dissecting single cell dynamics that coordinate neural crest migration and diversification

     Principal investigators: Thomas F Schilling (contact PI), Qing Nie

     $541,385

     award amount
   • 5R01AR067797-08Department: NIH department code

     Developmental regulation of cranial tendon fibroblast diversity and ECM interactions
     $366,382

     award amount

9. Aimee L Edinger

   Leads 2 awards · $900,545

   • 5R01CA247556-05Department: NIH department code

     Defining the role of macropinocytosis in solid tumor growth and therapeutic resistance
     $456,227

     award amount
   • 5R01CA254360-04Department: NIH department code

     A novel strategy to overcome drug resistance in cancer
     $444,318

     award amount

10. Bruce Blumberg

    Leads 2 awards · $653,040

    • 5R01ES023316-12Department: NIH department code

      Chromatin contacts are germline-transmissable vehicles underlying epigenetic transgenerational inheritance

      Principal investigators: Bruce Blumberg (contact PI), Toshihiro Shioda

      $640,087

      award amount
    • 3R01ES031139-04S1Department: NIH department code

      Interactions between prenatal obesogen exposure and Total Western diet lead to a transgenerational thrifty phenotype: functional and epigenomic analysis of effects in fat and liver

      Principal investigators: Bruce Blumberg (contact PI), Toshihiro Shioda

      $12,953

      award amount

11. Wenqi Wang

    Leads 2 awards · $627,293

    • 5R01GM126048-07Department: NIH department code

      Regulation and function of the Hippo pathway in growth control
      $323,420

      award amount
    • 5R01GM143233-03Department: NIH department code

      Interplay of heavy metal homeostasis and cell growth-related signaling networks

      Principal investigators: Wenqi Wang (contact PI), Rahul Warrior

      $303,873

      award amount

12. David C Lyon

    Leads 1 award · $583,625

    • 5R01EY032948-03Department: NIH department code

      Retinal sheet transplant impact on functional organization of visual cortex in retinal degenerate animal models

      Principal investigators: David C Lyon (contact PI), Magdalene J Seiler

      $583,625

      award amount

13. Maksim V Plikus

    Leads 1 award · $531,355

    • 5R01AR079150-03Department: NIH department code

      Tissue Size and Precision Control in Growing Hair Follicles

      Principal investigators: Maksim V Plikus (contact PI), Qing Nie

      $531,355

      award amount

14. Christine M Gall

    Leads 2 awards · $472,954

    • 5R01HD101642-04Department: NIH department code

      Postnatal Oxytocin Treatment and Cognitive Function in Fragile X

      Principal investigators: Christine M Gall (contact PI), Gary S Lynch

      $451,894

      award amount
    • 3R01HD101642-04S1Department: NIH department code

      Postnatal Oxytocin Treatment and Cognitive Function in Fragile X

      Principal investigators: Christine M Gall (contact PI), Gary S Lynch

      $21,060

      award amount

15. Ken W.y. Cho

    Leads 1 award · $410,119

    • 5R35GM139617-04Department: NIH department code

      Maternal transcription factors shaping early embryonic chromatin landscape
      $410,119

      award amount

16. Evgeny Kvon

    Leads 1 award · $400,369

    • 1R01HD115268-01A1Department: NIH department code

      Decoding the Mechanism of Pathogenic Enhancer Mutations In Congenital Limb Disorders
      $400,369

      award amount

17. Pablo Andres Lara-Gonzalez

    Leads 1 award · $381,220

    • 5R35GM150786-02Department: NIH department code

      Developmental regulation of the cell cycle machinery
      $381,220

      award amount

18. Laura Ewell

    Leads 1 award · $380,725

    • 5R01NS128222-02Department: NIH department code

      Determining the shared neuronal network mechanisms of focal epileptic discharges and impaired memory processing in temporal lobe epilepsy
      $380,725

      award amount

19. Dae Seok Eom

    Leads 1 award · $379,597

    • 5R35GM142791-04Department: NIH department code

      Signaling at a distance mediated by vesicles on novel cellular protrusions
      $379,597

      award amount

20. Arthur D Lander

    Leads 1 award · $319,250

    • 5T32GM136624-05Department: NIH department code

      Mathematical, Computational and Systems Biology

      Principal investigators: Arthur D Lander (contact PI), Qing Nie

      $319,250

      award amount

21. Sha Sun

    Leads 1 award · $318,556

    • 5R01GM141424-04Department: NIH department code

      Elucidating the molecular basis of lncRNA evolution for mammalian dosage compensation
      $318,556

      award amount

22. Xiaoyu Shi

    Leads 1 award · $270,116

    • 3DP2GM150017-01S1Department: NIH department code

      3D spatial single-cell multiomics mapping of Alzheimer's disease
      $270,116

      award amount

23. Cassandra Leigh Kooiker

    Leads 1 award · $53,974

    • 5F30MH126615-03Department: NIH department code

      The thalamic paraventricular nucleus mediates the influence of early-life adversity on reward-seeking behaviors
      $53,974

      award amount

24. Gregory De Carvalho

    Leads 1 award · $45,563

    • 1F31MH138115-01Department: NIH department code

      The Impact of Early Life Adversity on mGluR5-driven Endocannabinoid Signaling and Behavioral Adaptability
      $45,563

      award amount

25. Grace Cabot Bower

    Leads 1 award · $45,458

    • 5F31HD112201-02Department: NIH department code

      Characterizing a mechanism of enhancer-promoter interaction in vivo
      $45,458

      award amount

26. Ethan W Hollingsworth

    Leads 1 award · $45,134

    • 5F30HD110233-02Department: NIH department code

      Deciphering Mechanisms of Limb Malformations Caused by Noncoding Variants In Vivo
      $45,134

      award amount

27. Alexa Marie Tierno

    Leads 1 award · $44,751

    • 5F31NS132447-02Department: NIH department code

      Imaging progressive circuit reorganization after traumatic brain injury
      $44,751

      award amount

28. Bernardo Maximiliano Garduno

    Leads 1 award · $44,751

    • 1F31AG082485-01A1Department: NIH department code

      Neuropathological and spatial transcriptome brain maps in Octodon degus, a natural Alzheimer's disease rodent model
      $44,751

      award amount

29. Tallie Z. Baram

    Leads 1 award · $11,626

    • 2T32NS045540-21Department: NIH department code

      Epilepsy Research Training Program

      Principal investigators: Tallie Z. Baram (contact PI), Robert F Hunt

      $11,626

      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.

• Bing Ren

  Co-investigator on 5R01AG082127-02, led by Xiangmin Xu; 5R24AG073198-04, led by Xiangmin Xu; 5R01AG067153-05, led by Xiangmin Xu; 5U01DA052769-05, led by Xiangmin Xu; 3U01DA052769-04S1, led by Xiangmin Xu

  From the FY2024 awards this person leads

  • University of California, San Diego · Other Basic Sciences (NIH department code, 2 awards)

• Kim Green

  Co-investigator on 5U01AG076791-03, led by Xiangmin Xu; 4R01AG065329-02, led by Daniele Piomelli

  From the FY2024 awards this person leads

  • University of California-Irvine · Other Basic Sciences (NIH department code, 2 awards)

• Eran A Mukamel

  Co-investigator on 5U01AG076791-03, led by Xiangmin Xu

  From the FY2024 awards this person leads

  • University of California, San Diego · Psychology (NIH department code, 1 award)

• Wei Xu

  Co-investigator on 5U01AG076791-03, led by Xiangmin Xu

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Barbara J Wold

  Co-investigator on 5UM1HG012077-04, led by Seyed Ali Mortazavi

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Michael D Koob

  Co-investigator on 5R01AG082127-02, led by Xiangmin Xu

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Qing Nie

  Co-investigator on 5R01DE030565-04, led by Thomas F Schilling; 5R01AR079150-03, led by Maksim V Plikus; 5T32GM136624-05, led by Arthur D Lander

  From the FY2024 awards this person leads

  • University of California-Irvine · Biostatistics & Math Sciences (NIH department code, 1 award)

• Ming Tan

  Co-investigator on 5R01AI151212-05, led by Christine Suetterlin; 5R01AI153410-05, led by Christine Suetterlin

  From the FY2024 awards this person leads

  • University of California-Irvine · Microbiology & Immunology (NIH department code, 1 award)

• Gordon J Fishell

  Co-investigator on 5U24MH133236-02, led by Xiangmin Xu

  From the FY2024 awards this person leads

  • Harvard Medical School · Biology (NIH department code, 2 awards)
  • Broad Institute, Inc. (no department on record, 1 award)

• Julian F. Thayer

  Co-investigator on 5R01MH128306-02, led by Michael A Yassa; 3R01MH128306-02S1, led by Michael A Yassa

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Daniela Boassa

  Co-investigator on 5R01AI151212-05, led by Christine Suetterlin

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• German Andres Enciso

  Co-investigator on 5R01AI151212-05, led by Christine Suetterlin

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Toshihiro Shioda

  Co-investigator on 5R01ES023316-12, led by Bruce Blumberg; 3R01ES031139-04S1, led by Bruce Blumberg

  From the FY2024 awards this person leads

  • Massachusetts General Hospital · Genetics (topic-inferred, 1 award)
  • Massachusetts General Hospital · Biomedical Engineering (topic-inferred, 1 award)
  • Massachusetts General Hospital · Neurosciences (topic-inferred, 1 award)

• Magdalene J Seiler

  Co-investigator on 5R01EY032948-03, led by David C Lyon

  From the FY2024 awards this person leads

  • University of California-Irvine · Ophthalmology (NIH department code, 1 award)

• Andre Obenaus

  Co-investigator on 5R01NS121246-04, led by Xiangmin Xu

  From the FY2024 awards this person leads

  • University of California Riverside (no department on record, 2 awards)

• Gary S Lynch

  Co-investigator on 5R01HD101642-04, led by Christine M Gall; 3R01HD101642-04S1, led by Christine M Gall

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Rahul Warrior

  Co-investigator on 5R01GM143233-03, led by Wenqi Wang

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Todd C Holmes

  Co-investigator on 1T32AG081185-01A1, led by Xiangmin Xu

  From the FY2024 awards this person leads

  • University of California-Irvine · Physiology (NIH department code, 2 awards)

• Nancy G. Guerra

  Co-investigator on 5R25GM146300-03, led by Michael A Yassa

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Bruce L McNaughton

  Co-investigator on 2T32MH119049-06, led by Michael A Yassa

  From the FY2024 awards this person leads

  • University of California-Irvine · Other Basic Sciences (NIH department code, 1 award)

• Manuella Yassa

  Co-investigator on 2T32MH119049-06, led by Michael A Yassa

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.