Genetics at University of Massachusetts Medical School Worcester

Leads a grant in this department

45 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Andrei Korostelev

   Leads 2 awards · $2,305,999

   • 1R01HL183308-01Department: NIH department code

     Molecular principles of translational reprogramming by angiogenin
     $1,660,688

     award amount
   • 5R35GM127094-09Department: NIH department code

     Translational Control: Discovery and Mechanisms
     $645,311

     award amount

2. Phillip Tai

   Leads 2 awards · $1,842,500

   • 1R01GM155648-01A1Department: NIH department code

     Interrogating the roles of truncated/mutated inverted terminal repeat sequences in adeno-associated virus vectors in transgene stability through episome formation and host cell genome integration
     $1,675,000

     award amount
   • 5R21AI183080-02Department: NIH department code

     In vitro and in vivo modeling of gene therapy vector stability when challenged by natural virus infection in human hepatocytes
     $167,500

     award amount

3. Anastasia Khvorova

   Leads 3 awards · $1,568,767

   • 5R01NS104022-09Department: NIH department code

     Expanding the Chemical Diversity of Therapeutic Oligonucleotides
     $688,196

     award amount
   • 5R35GM131839-07Department: NIH department code

     Chemical engineering of therapeutic RNAs for extrahepatic delivery
     $460,625

     award amount
   • 1R01AG099051-01Department: NIH department code

     RNAi-Mediated Combinatorial Modulation of ApoE, Innate Immune Response, and Tau Pathology for a Disease-Modifying Treatment of Alzheimer's Disease (AD)
     $419,946

     award amount

4. A. J. Marian Walhout

   Leads 2 awards · $1,510,440

   • 5R35GM122502-10Department: NIH department code

     Gene regulatory and metabolic network structure, function and evolution
     $843,915

     award amount
   • 5R01DK068429-20Department: NIH department code

     C. elegans models of metabolism in health and disease
     $666,525

     award amount

5. Jennifer Eileen Adair

   Leads 2 awards · $1,309,920

   • 5R01AI167009-05Department: NIH department code

     In vivo CRISPR engineering of B cells to produce anti-HIV broadly neutralizing antibodies using novel nanoparticles

     Principal investigators: Jennifer Eileen Adair (contact PI), Justin J Taylor

     $717,470

     award amount
   • 5R01AI158728-05Department: NIH department code

     Targeted genetic engineering of B cells to induce protective antibody responses to pathogens

     Principal investigators: Jennifer Eileen Adair (contact PI), Justin J Taylor

     $592,450

     award amount

6. Heather L Gray-Edwards

   Leads 2 awards · $1,299,360

   • 5R01NS145295-02Department: NIH department code

     Evaluating the efficiency of in vivo gene transfer to correct the molecular neuropathology causing psychiatric disease in MSUD
     $652,662

     award amount
   • 5R01NS139268-03Department: NIH department code

     AAV Gene Therapy for Sialidosis: from Mice to IND
     $646,698

     award amount

7. Athma A Pai

   Leads 2 awards · $1,219,395

   • 5R01HG012967-04Department: NIH department code

     A kinetic framework to map the genetic determinants of alternative RNA isoform expression

     Principal investigators: Athma A Pai (contact PI), Barbara Engelhardt

     $740,345

     award amount
   • 5R35GM133762-07Department: NIH department code

     Tracking transcriptome diversity in real-time
     $479,050

     award amount

8. Jae-Hyuck Shim

   Leads 2 awards · $1,118,893

   • 5R01AR086572-02Department: NIH department code

     Development of a long-lasting, bone-targeted gene therapy for osteogenesis imperfecta
     $617,739

     award amount
   • 5R01AR078230-05Department: NIH department code

     Novel approaches to promote healing of bone loss in inflammatory arthritis

     Principal investigators: Jae-Hyuck Shim (contact PI), Ellen M Gravallese

     $501,154

     award amount

9. Vanni Bucci

   Leads 1 award · $836,691

   • 1R01AI194527-01A1Department: NIH department code

     Investigating the nonlinear complex dynamics of the tuft cell-microbiome cross-talk: the impact of feedback loops on immune regulation, microbial modulation and response to tissue insults

     Principal investigators: Vanni Bucci (contact PI), Andrea Reboldi

     $836,691

     award amount

10. Michael Jungho Lee

    Leads 2 awards · $832,790

    • 5R35GM152194-03Department: NIH department code

      Systems and Network-level Regulation of Cell Death
      $418,750

      award amount
    • 5U01CA305435-02Department: NIH department code

      MEDUSA(GM): an analysis platform for resolving mechanisms of action for anti-cancer drugs
      $414,040

      award amount

11. Job Dekker

    Leads 1 award · $731,771

    • 5R01HG003143-21Department: NIH department code

      Structural Annotation of the Human Genome
      $731,771

      award amount

12. Jonathan K Watts

    Leads 1 award · $665,737

    • 5R01NS111990-08Department: NIH department code

      Multi-Targeting Oligonucleotide Therapeutics for Familial and Sporadic Amyotrophic Lateral Sclerosis

      Principal investigators: Jonathan K Watts (contact PI), Robert H Brown

      $665,737

      award amount

13. Toloo Taghian

    Leads 1 award · $659,245

    • 1R01NS146452-01Department: NIH department code

      Development of a Gene Therapy for UBA5 Deficiency
      $659,245

      award amount

14. Wen Xue

    Leads 1 award · $625,607

    • 5R01CA275945-04Department: NIH department code

      In vivo prime editing for precision cancer mouse models
      $625,607

      award amount

    Also a principal investigator on 5R01GM150273-04, led by Erik J. Sontheimer.

15. Guocai Zhong

    Leads 1 award · $609,675

    • 5R01EB037025-02Department: NIH department code

      Synthetic RNA Switch-Based Temporal and Dose Control of in Vivo Gene Therapies
      $609,675

      award amount

16. Erik J. Sontheimer

    Leads 1 award · $583,738

    • 5R01GM150273-04Department: NIH department code

      Advanced Delivery Platforms for Base Editing In Vivo

      Principal investigators: Erik J. Sontheimer (contact PI), Wen Xue

      $583,738

      award amount

17. Cynthia N Fuhrmann

    Leads 1 award · $539,502

    • 5R25GM160996-02Department: NIH department code

      Mentorship Education to Advance Biomedical Research Career Development

      Principal investigators: Cynthia N Fuhrmann (contact PI), Christine E Pfund

      $539,502

      award amount

18. Guangping Gao

    Leads 1 award · $530,432

    • 5R01NS076991-12Department: NIH department code

      Oligodendrocyte-focused rAAV gene therapy strategies for Canavan disease and Leukodystrophies
      $530,432

      award amount

19. Phillip D Zamore

    Leads 1 award · $525,064

    • 2R35GM136275-06Department: NIH department code

      Understanding the Evolution, Biology, and Molecular Mechanism of Argonaute
      $525,064

      award amount

20. Amir Mitchell

    Leads 1 award · $460,625

    • 5R35GM133775-07Department: NIH department code

      Interactions underlying resilient bacterial communities and successful colonization of host niches
      $460,625

      award amount

21. Craig C Mello

    Leads 1 award · $460,625

    • 5R35GM153442-03Department: NIH department code

      Investigation of RNA interference and related gene regulatory mechanisms
      $460,625

      award amount

22. Emma V. Watson

    Leads 1 award · $460,625

    • 5R35GM160085-02Department: NIH department code

      Modeling Aneuploidy-Driven Phenotypes Across Tissues
      $460,625

      award amount

23. Jun Xie

    Leads 1 award · $460,625

    • 1R21NS146929-01A1Department: NIH department code

      AAV-mediated gene silencing for the treatment of Hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC)
      $460,625

      award amount

24. Robert Charles Brewster

    Leads 1 award · $460,625

    • 1R35GM161523-01Department: NIH department code

      Uncovering the fundamental principles of transcriptional regulation
      $460,625

      award amount

25. Elizabeth Anne Shank

    Leads 1 award · $418,750

    • 5R35GM145261-05Department: NIH department code

      Investigating the molecules and mechanisms of bacterial cell-cell interactions
      $418,750

      award amount

26. Li Li

    Leads 1 award · $418,750

    • 5R35GM155169-03Department: NIH department code

      IRES-mediated translation: mechanisms and applications in mRNA therapeutics
      $418,750

      award amount

27. Wenwen Fang

    Leads 1 award · $418,750

    • 5R35GM150953-04Department: NIH department code

      Understanding double-stranded RNA recognition in human cells
      $418,750

      award amount

28. Qinglan Ling

    Leads 1 award · $241,357

    • 5R00HD109359-05Department: NIH department code

      First murine animal model and adeno-associated virus (AAV)-based gene therapy for MTATP6 mitochondrial diseases
      $241,357

      award amount

29. Qi Tang

    Leads 1 award · $232,328

    • 5R00AR082987-04Department: NIH department code

      Developing a programmable siRNA-based therapeutic platform for gene silencing in the skin
      $232,328

      award amount

30. Zintis Inde

    Leads 1 award · $132,472

    • 5K99AG086405-02Department: NIH department code

      Apoptotic Dysregulation Across Cell Types in Aging and Neurodegeneration
      $132,472

      award amount

31. Julianna E Buchwald

    Leads 1 award · $52,007

    • 5F30DK131853-05Department: NIH department code

      Investigating siRNA-mediated inhibition of ischemia-reperfusion injury during the liver transplantation process
      $52,007

      award amount

32. Laurel Blaine Stine

    Leads 1 award · $38,153

    • 1F31AI197867-01Department: NIH department code

      Defining mechanisms that regulate plasma membrane rupture
      $38,153

      award amount

33. Rebecca S Panwala-Sciambra

    Leads 1 award · $36,081

    • 1F30CA306325-01A1Department: NIH department code

      High throughput screening to generate and investigate cancer driver mutations in hepatocellular carcinoma.
      $36,081

      award amount

34. Sara Keane

    Leads 1 award · $35,454

    • 1F31HD123790-01Department: NIH department code

      Investigating how histone methyltransferases cause gene silencing in the C. elegans germline
      $35,454

      award amount

35. Arshia Kaur

    Leads 1 award · $35,446

    • 1F31CA306339-01A1Department: NIH department code

      Exploring autophagy as a cellular response to fusion oncogene-induced stress
      $35,446

      award amount

36. Eva Jazbec

    Leads 1 award · $35,446

    • 1F31AI203274-01Department: NIH department code

      Reprogramming the Core Spliceosome in Innate Immunity
      $35,446

      award amount

37. David Cooper

    Leads 1 award · $34,946

    • 1F31AR086004-01A1Department: NIH department code

      Development of a Combinatorial siRNA Therapy for the Treatment of Fibrodysplasia Ossificans Progressiva
      $34,946

      award amount

38. Emily Sholi

    Leads 1 award · $34,946

    • 5F31HL180041-02Department: NIH department code

      Translational control in heart and lung disease by RNase A family
      $34,946

      award amount

39. Grace Schiefelbein

    Leads 1 award · $34,946

    • 5F31HD118787-02Department: NIH department code

      Probing the Mammalian piRISC Cleavage Mechanism
      $34,946

      award amount

40. Jesse William Lehman

    Leads 1 award · $34,946

    • 5F31AI189160-02Department: NIH department code

      Temporal Regulation of mRNA Biogenesis in Immune Responses
      $34,946

      award amount

41. Kim Anh Vu

    Leads 1 award · $34,946

    • 1F31HL184773-01Department: NIH department code

      Engineering circularly structured guide RNA for sustained CRISPRi-mediated suppression of Idiopathic Pulmonary Fibrosis drivers.
      $34,946

      award amount

42. Nicholas Gaston

    Leads 1 award · $34,946

    • 5F31HL176178-03Department: NIH department code

      A single prime editing strategy for correcting diverse mutations responsible for RBM20-associated dilated cardiomyopathy
      $34,946

      award amount

43. Jenny Gao

    Leads 1 award · $34,920

    • 5F30HL176024-03Department: NIH department code

      Developing a novel adenine base editor tool for in vivo alpha-1 antitrypsin deficiency gene correction.
      $34,920

      award amount

44. Sarah Jane Allen

    Leads 1 award · $34,920

    • 5F31NS137681-03Department: NIH department code

      Examining the Role of a Pathogenic HTT Isoform, HTT1a, in Somatic Expansion and RNA Aggregation in Huntington's Disease
      $34,920

      award amount

45. Alejandro Felix Mejia

    Leads 1 award · $34,344

    • 5F31GM157877-02Department: NIH department code

      Engineering bacterial group I introns for efficient production of safe and durable nucleoside-modified circular mRNA therapeutics
      $34,344

      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.

• Justin J Taylor

  Co-investigator on 5R01AI167009-05, led by Jennifer Eileen Adair; 5R01AI158728-05, led by Jennifer Eileen Adair

  From the FY2026 awards this person leads

  • University of Washington · Internal Medicine (NIH department code, 1 award)

• Andrea Reboldi

  Co-investigator on 1R01AI194527-01A1, led by Vanni Bucci

  From the FY2026 awards this person leads

  • University of Massachusetts Medical School Worcester · Pathology (NIH department code, 2 awards)

• Barbara Engelhardt

  Co-investigator on 5R01HG012967-04, led by Athma A Pai

  From the FY2026 awards this person leads

  • J. David Gladstone Institutes (no department on record, 1 award)

• Robert H Brown

  Co-investigator on 5R01NS111990-08, led by Jonathan K Watts

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Christine E Pfund

  Co-investigator on 5R25GM160996-02, led by Cynthia N Fuhrmann

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Ellen M Gravallese

  Co-investigator on 5R01AR078230-05, led by Jae-Hyuck Shim

  From the FY2026 awards this person leads

  • Brigham and Women's Hospital · Internal Medicine (investigator's affiliation, 1 award)