Pharmacology at University of North Carolina at Chapel Hill

Leads a grant in this department

52 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Crews, Fulton T

   Leads 6 awards · $3,781,975

   • 5P60AA011605-22Department: NIH department code

     Molecular and Circuit Pathogenesis of Alcohol Addiction
     $1,743,681

     award amount
   • 5T32AA007573-22Department: NIH department code

     Molecular and Cellular Alcohol Research Training
     $494,653

     award amount
   • 5U01AA020023-10Department: NIH department code

     5/8 NADIA U01 Adolescent Alcohol and Adult Brian Dysfunction
     $478,456

     award amount
   • 5U24AA020024-10Department: NIH department code

     1/1 NADIA Administrative Core
     $402,835

     award amount
   • 3P60AA011605-22S1Department: NIH department code

     Neuroimmune Sensitization and Circuit Pathogenesis: An Alzheimer’s supplement to P60-AA011605: Molecular and Circuit Pathogenesis of Alcohol Addiction
     $388,750

     award amount
   • 5U54AA019767-10Department: NIH department code

     2/2 Mechanisms of alcohol pathology: A collaborative partnership between NCCU & UNC
     $273,600

     award amount

2. Roth, Bryan L.

   Leads 3 awards · $3,480,747

   • 5U24DK116195-03Department: NIH department code

     Illuminating the Druggable GPCR-ome
     $2,243,887

     award amount
   • 5R37DA045657-02Department: NIH department code

     Mechanistic insights into LSD actions at 5-HT2A serotonin receptors
     $634,832

     award amount
   • 5R01MH112205-03Department: NIH department code

     Molecular Details of Psychoactive Drug Actions
     $602,028

     award amount

3. Der, Channing J.

   Leads 3 awards · $2,451,083

   • 5P01CA203657-04Department: NIH department code

     Defining RAS isoform- and mutation-specific roles in oncogenesis
     $1,491,448

     award amount
   • 5R35CA232113-02Department: NIH department code

     Targeting undruggable RAS for cancer treatment
     $894,826

     award amount
   • 3P01CA203657-04S1Department: NIH department code

     Defining RAS isoform- and mutation-specific roles in oncogenesis
     $64,809

     award amount

4. Johnson, Gary L.

   Leads 1 award · $2,265,987

   • 5U24DK116204-03Department: NIH department code

     Illuminating Function of the Understudied Druggable Kinome
     $2,265,987

     award amount

5. Kash, Thomas L.

   Leads 6 awards · $1,636,253

   • 3U01AA020911-08S1Department: NIH department code

     Probing Ethanol Induced Acceleration of Hindbrain and Amygdalar Pathology in an Alzheimer’s Disease Model
     $387,910

     award amount
   • 5U01AA020911-08Department: NIH department code

     6/8: INIA Stress and Chronic Alcohol Interactions: Deconstructing the role of extended amygdala circuits in stress regulated alcohol drinking
     $380,000

     award amount
   • 5R01AA019454-10Department: NIH department code

     The Role of Serotonin in Alcohol-Withdrawal Induced Anxiety
     $379,187

     award amount
   • 5U24AA025475-03Department: NIH department code

     Core 1: Brain Circuit Validation Core
     $228,000

     award amount
   • 1R21AA027460-01A1Department: NIH department code

     Dissecting the role of ethanol-induced plasticity in the PAG to BNST pathway in pain-related behaviors
     $218,691

     award amount
   • 3U01AA020911-08S2Department: NIH department code

     6/8: INIA Stress and Chronic Alcohol Interactions: Deconstructing the role of extended amygdala circuits in stress regulated alcohol drinking
     $42,465

     award amount

6. Ainslie, Kristy M

   Leads 2 awards · $1,468,567

   • 5R01AI125147-04Department: NIH department code

     Host Targeted Therapy for Drug Resistant Salmonella and Francisella infection
     $1,092,009

     award amount
   • 5R01AI137525-02Department: NIH department code

     Biomaterials to study tolerance immune induction kinetics
     $376,558

     award amount

7. James, Lindsey Ingerman

   Leads 2 awards · $1,237,349

   • 5R61DA047023-02Department: NIH department code

     POLYCOMB REPRESSIVE COMLEXE AS KEY REGULATORS OF HIV LATENCY AND TARGETS FOR LATENCY REVERSAL
     $890,017

     award amount
   • 1R01CA242305-01Department: NIH department code

     DISCOVERY OF FIRST-IN-CLASS NSD2 DEGRADERS FOR CANCER THERAPY
     $347,332

     award amount

8. Frye, Stephen Vernon

   Leads 3 awards · $1,094,309

   • 5R01CA218392-02Department: NIH department code

     DISCOVERY OF IN VIVO CHEMICAL PROBES FOR POLYCOMB CBX DOMAINS
     $504,942

     award amount
   • 5R01GM100919-08Department: NIH department code

     Discovery of Chemical Probes for Chromatin Readers
     $416,687

     award amount
   • 5R21CA216673-02Department: NIH department code

     Modulating the DNA methylation program through UHRF1 antagonism
     $172,680

     award amount

9. Kashuba, Angela D

   Leads 1 award · $1,009,616

   • 5R01AI122319-04Department: NIH department code

     Novel Mass Spectrometry Imaging Methods to Quantify Antiretroviral Adherence
     $1,009,616

     award amount

10. Song, Juan

    Leads 3 awards · $912,745

    • 5R01MH111773-04Department: NIH department code

      Neural circuitry mechanisms regulating adult hippocampal neurogenesis
      $447,355

      award amount
    • 5R21NS104530-02Department: NIH department code

      Role of TRIM9 in regulating neurogenesis-associated hippocampal functions
      $233,250

      award amount
    • 5R21AG058160-02Department: NIH department code

      Targeting inhibitory neural network for treatment of Alzheimers disease
      $232,140

      award amount

11. Tropsha, Alexander

    Leads 1 award · $882,674

    • 3OT2TR002514-01S1Department: NIH department code

      Biomedical Data Translator Technical Feasibility Assessment of Reasoning Tool: University of North Carolina at Chapel Hill
      $882,674

      award amount

12. Hahn, Klaus M.

    Leads 1 award · $789,940

    • 5R35GM122596-03Department: NIH department code

      Dissecting signaling in vivo via precise control and visualization of protein activity
      $789,940

      award amount

13. Brouwer, Kim L.r.

    Leads 1 award · $737,877

    • 5T32GM086330-09Department: NIH department code

      UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program
      $737,877

      award amount

14. Gonzalez, Daniel

    Leads 2 awards · $667,439

    • 5R01HD096435-02Department: NIH department code

      Physiologically-Based Pharmacokinetic Modeling to Guide Drug Dosing in Children with Obesity
      $512,014

      award amount
    • 5K23HD083465-05Department: NIH department code

      Use of Physiologically-Based PK/PD Models to Streamline Drug Approvals
      $155,425

      award amount

15. Lai, Samuel

    Leads 1 award · $664,881

    • 5R01HL141934-02Department: NIH department code

      Overcoming anti-PEG immunity to restore prolonged circulation and efficacy of PEGylated therapeutics
      $664,881

      award amount

16. Batrakova, Elena

    Leads 2 awards · $661,155

    • 5R01NS102412-02Department: NIH department code

      Cell-based Platform for Gene Delivery to the Brain
      $338,579

      award amount
    • 1R01NS112019-01Department: NIH department code

      Extracellular Vesicles for CNS Delivery of Therapeutic Enzymes to Treat Lysosomal Storage Disorders
      $322,576

      award amount

17. Drewry, David Harold

    Leads 1 award · $630,383

    • 5R01CA218442-03Department: NIH department code

      Creation of in vivo active chemical probes for CAMKK2 to treat cancer
      $630,383

      award amount

18. Elston Lafata, Jennifer M

    Leads 1 award · $587,421

    • 5R01CA197205-05Department: NIH department code

      e-Assist: A Post-Visit Patient Portal Tool to Promote Colorectal Cancer Screening
      $587,421

      award amount

19. Bronich, Tatiana K

    Leads 1 award · $545,618

    • 5U01CA198910-05Department: NIH department code

      Targeted Core Shell Nanogels for Triple Negative Breast Cancer
      $545,618

      award amount

20. Nguyen, Juliane

    Leads 1 award · $482,859

    • 7R01EB023262-03Department: NIH department code

      RNA EXO-Codes: A novel way to reprogram pathological exosomes
      $482,859

      award amount

21. Sondek, John E

    Leads 2 awards · $472,139

    • 5R01GM057391-19Department: NIH department code

      Regulation of phospholipase C
      $403,371

      award amount
    • 3R01GM057391-19S1Department: NIH department code

      Regulation of phospholipase C
      $68,768

      award amount

22. Elston, Timothy C

    Leads 1 award · $450,950

    • 5R35GM127145-02Department: NIH department code

      Mathematical modeling of cellular signaling systems
      $450,950

      award amount

23. Lee, Andrew L

    Leads 1 award · $401,435

    • 1R01GM127698-01A1Department: NIH department code

      Structural and Dynamic Mechanisms in Classical Protein Allostery
      $401,435

      award amount

24. Calabrese, Joseph Mauro

    Leads 2 awards · $390,059

    • 5R01GM121806-03Department: NIH department code

      Mechanisms of gene silencing induced by long noncoding RNAs
      $316,141

      award amount
    • 3R01GM121806-03S1Department: NIH department code

      Mechanisms of gene silencing induced by long noncoding RNAs
      $73,918

      award amount

25. Brown, Nicholas Gene

    Leads 1 award · $388,750

    • 5R35GM128855-02Department: NIH department code

      Spindle Assembly Checkpoint Silencing
      $388,750

      award amount

26. Bowers, Albert A

    Leads 1 award · $383,398

    • 5R35GM125005-03Department: NIH department code

      Chemoenzymatic Synthesis, Mode of Action and Evolution of Natural Product-based Macrocycles
      $383,398

      award amount

27. McGinty, Robert

    Leads 1 award · $382,895

    • 1R35GM133498-01Department: NIH department code

      Molecular Mechanisms of Chromatin Recognition
      $382,895

      award amount

28. Besheer, Joyce

    Leads 1 award · $380,000

    • 5R01AA025582-04Department: NIH department code

      Unbiased analysis of molecular and circuit targets of low dose alcohol
      $380,000

      award amount

29. Liu, Rihe

    Leads 1 award · $358,307

    • 5R01GM120291-04Department: NIH department code

      Inhibition of GTPases and G proteins to treat human disease
      $358,307

      award amount

30. Herman, Melissa A

    Leads 1 award · $349,875

    • 1R01AA026858-01A1Department: NIH department code

      The role of a nucleus tractus solitarius-central amygdala circuit in alcohol-induced plasticity and drinking behavior
      $349,875

      award amount

31. Lawrence, David S.

    Leads 1 award · $340,156

    • 5R01NS103486-02Department: NIH department code

      Spatiotemporal Control of Migratory Cellular Behavior
      $340,156

      award amount

32. Kabanov, Alexander V

    Leads 1 award · $334,212

    • 5R01CA184088-05Department: NIH department code

      Liposomal Doxorubicin and Pluronic Combination for Cancer Therapy
      $334,212

      award amount

33. Liu, Jian

    Leads 1 award · $333,991

    • 1R01HL144970-01Department: NIH department code

      Synthesis and Pharmacological Evaluation of Homogenous Ultra-Low Molecular Weight Heparins
      $333,991

      award amount

34. Dumond, Julie Brumer

    Leads 2 awards · $330,153

    • 1R21AG063660-01A1Department: NIH department code

      Interaction of Nucleoside Reverse Transcriptase Inhibitor Pharmacology and Aging in the Multicenter AIDS Cohort Study
      $193,450

      award amount
    • 5R21AG058490-02Department: NIH department code

      Effects of Aging and Inflammation on Intracellular Nucleoside Reverse Transcriptase Inhibitor Pharmacology in the WIHS Cohort
      $136,703

      award amount

35. Hingtgen, Shawn

    Leads 1 award · $328,885

    • 5R01NS097507-04Department: NIH department code

      Nanofiber matrices to improve neural stem cell-mediated cancer therapy
      $328,885

      award amount

36. Cox, Adrienne D

    Leads 1 award · $323,651

    • 3U01CA199235-04S1Department: NIH department code

      Identification of synthetic lethal interactors in pancreatic cancer
      $323,651

      award amount

37. Hathaway, Nathaniel A.

    Leads 1 award · $306,188

    • 5R01GM118653-03Department: NIH department code

      MECHANISM OF HP1-MEDIATED HETEROCHROMATIN ASSEMBLY AND DURABILITY IN LIVE CELLS
      $306,188

      award amount

38. Emanuele, Michael James

    Leads 1 award · $301,840

    • 5R01GM120309-04Department: NIH department code

      SCF Ubiquitin Ligases in Cell Cycle Control and Chromosome Stability
      $301,840

      award amount

39. Cottrell, MacKenzie

    Leads 1 award · $287,052

    • 1R21AI145646-01Department: NIH department code

      Feminizing Sex Hormones Impact on PrEP Pharmacology in Transgender Women
      $287,052

      award amount

40. Huang, Xi-Ping

    Leads 1 award · $256,925

    • 1R21MH120422-01Department: NIH department code

      Designing and developing PAM-antagonists for GPR68
      $256,925

      award amount

41. Nicholas, Robert A

    Leads 1 award · $233,568

    • 5T32GM007040-45Department: NIH department code

      Predoctoral Training in Pharmacological Sciences
      $233,568

      award amount

42. Mosedale, Merrie

    Leads 1 award · $223,571

    • 1R21OD028216-01Department: NIH department code

      Development of an in vitro mouse genetic reference platform to improve preclinical drug safety assessment
      $223,571

      award amount

43. Strachan, Ryan Thomas

    Leads 1 award · $110,409

    • 5K01MH109943-04Department: NIH department code

      Integrated discovery of tool molecules for illuminating the brain GPCRome
      $110,409

      award amount

44. Gurysh, Elizabeth Grace

    Leads 1 award · $63,746

    • 1F32CA225199-01A1Department: NIH department code

      Combination Therapy of Stem Cells and Drug Eluting Scaffolds to Treat Glioblastoma
      $63,746

      award amount

45. Klomp, Jennifer E

    Leads 1 award · $61,226

    • 1F32CA239328-01Department: NIH department code

      Defining the roles of ERK MAPK in driving KRAS-mutant pancreatic cancer growth.
      $61,226

      award amount

46. Murphy, Ryan Mary

    Leads 1 award · $45,816

    • 1F31DE028749-01Department: NIH department code

      Investigating the role of NRF2 in promoting radioresistance in oral squamous cell carcinoma.
      $45,816

      award amount

47. Yu, Waylin

    Leads 1 award · $36,927

    • 5F31AA027129-02Department: NIH department code

      Midbrain and extended amygdala contributions to sex differences in pain and alcohol withdrawal
      $36,927

      award amount

48. Beaudoin, James John

    Leads 1 award · $36,560

    • 1F31DK120196-01A1Department: NIH department code

      Elucidating the Role of Organic Solute Transporter (OST) Alpha/Beta in Bile Acid Transport and Drug Interactions
      $36,560

      award amount

49. Mercer-Smith, Alison R.

    Leads 1 award · $36,523

    • 1F30CA243270-01Department: NIH department code

      Therapeutic Engineered Stem Cells as a New Adjuvant Therapy for Non-Small Cell Lung Cancer Brain Metastases
      $36,523

      award amount

50. Vogt, Caleb D.

    Leads 1 award · $36,340

    • 1F31CA239322-01Department: NIH department code

      Chimeric Inhibitors of Androgen Biosynthesis and Signaling
      $36,340

      award amount

51. Agajanian, Megan

    Leads 1 award · $34,324

    • 1F99CA245724-01Department: NIH department code

      Mechanistic studies and therapeutic targeting of the WNT signaling pathway
      $34,324

      award amount

52. Lipner, Matthew

    Leads 1 award · $31,050

    • 5F30CA213916-03Department: NIH department code

      FOLFOX-induced kinome reprogramming in pancreatic cancer tumor xenografts
      $31,050

      award amount