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FY2025 NIH awards · Principal investigators

Pharmacology at University of North Carolina at Chapel Hill

Chapel Hill, NC

Funding
$27.1M
$27,112,757
Awards
63
FY2025 NIH awards in Pharmacology
Principal investigators
68
51 lead a grant here, 17 co-investigators
Department rank
#7
of 127 · Ranking
  • NIH names only the principal investigators on an award, so this page lists only them. The department is the award's: it is where ScienceDex counts the award, not a list of the department's members.
  • These are the awards in the Pharmacology row of the University of North Carolina at Chapel Hill page.

Leads a grant in this department

51 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

  1. Juliane Nguyen

    Leads 3 awards · $1,963,948

    • 1R01DK140954-01A1Department: NIH department code
      Targeted Probiotic Yeast for Treating Inflammatory Bowel Diseases

      Principal investigators: Juliane Nguyen (contact PI), Janelle C Arthur

      $790,359
      award amount
    • 5R01HL174038-02Department: NIH department code
      Maximizing Therapeutic Accumulation and Retention for Enhanced Cardiac Repair
      $692,843
      award amount
    • 5R01HL161456-04Department: NIH department code
      Engineering a cross-linked cellular network for cardiac repair
      $480,746
      award amount
  2. Juan Song

    Leads 3 awards · $1,909,246

    • 5R01MH132222-03Department: NIH department code
      Regulation and functional contribution of hypothalamic modified adult hippocampal neurogenesis
      $747,199
      award amount
    • 5R01AG084207-03Department: NIH department code
      Enhancing adult-born neurons to restore brain functions in Alzheimer's disease
      $700,646
      award amount
    • 5R01NS121300-05Department: NIH department code
      Role of Cholecystokinin in the Dentate Gyrus
      $461,401
      award amount

    Also a principal investigator on 1R21AG091124-01A1, led by Brent Asrican.

  3. Bryan L. Roth

    Leads 3 awards · $1,814,029

    • 5R37DA045657-08Department: NIH department code
      Mechanistic insights into LSD actions at 5-HT2A serotonin receptors
      $650,756
      award amount
    • 5R01MH112205-09Department: NIH department code
      Molecular Details of Psychoactive Drug Actions

      Principal investigators: Bryan L. Roth (contact PI), Brian K Shoichet

      $599,826
      award amount
    • 5R01DA055656-04Department: NIH department code
      STRUCTURE AND FUNCTION OF MRG-FAMILY RECEPTORS

      Principal investigators: Bryan L. Roth (contact PI), Brian K Shoichet

      $563,447
      award amount
  4. Elias Rosen

    Leads 1 award · $1,414,502

    • 1R01AI192048-01Department: NIH department code
      Assessing Time-to-Treatment Variability in Antiretroviral Penetration by Multimodal Imaging

      Principal investigators: Elias Rosen (contact PI), Jacob D Estes

      $1,414,502
      award amount
  5. Thomas L. Kash

    Leads 4 awards · $1,321,416

    • 5R01AA019454-14Department: NIH department code
      Extended Amygdala Regulation of Dorsal Raphe Function in Ethanol Self-Administration
      $499,436
      award amount
    • 5R01NS122230-05Department: NIH department code
      Determining the impact of BNST CRF systems on inflammatory pain-induced disruptions of behavior
      $395,372
      award amount
    • 5R01AA031450-02Department: NIH department code
      Probing Ethanol Dysregulation of Hypothalamic CRH neurons

      Principal investigators: Thomas L. Kash (contact PI), Jaideep Bains

      $314,945
      award amount
    • 3R01AA031450-02S1Department: NIH department code
      Probing Ethanol Dysregulation of Hypothalamic CRH neurons

      Principal investigators: Thomas L. Kash (contact PI), Jaideep Bains

      $111,663
      award amount
  6. Michael James Emanuele

    Leads 2 awards · $1,115,526

    • 5R35GM153250-02Department: NIH department code
      Proteostasis signaling in cell cycle control
      $581,076
      award amount
    • 2T32GM135095-06Department: NIH department code
      Pharmacological Sciences Training Program

      Principal investigators: Michael James Emanuele (contact PI), Joseph Mauro Calabrese

      $534,450
      award amount
  7. Klaus M. Hahn

    Leads 1 award · $810,270

    • 5R35GM122596-09Department: NIH department code
      Dissecting signaling in vivo via precise control and visualization of protein activity
      $810,270
      award amount
  8. Kim L.r. Brouwer

    Leads 1 award · $799,378

    • 5T32GM086330-15Department: NIH department code
      UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program

      Principal investigators: Kim L.r. Brouwer (contact PI), Daniel Gonzalez, Paul B Watkins

      $799,378
      award amount
  9. Alexander Tropsha

    Leads 1 award · $786,413

    • 5U24ES035214-04Department: NIH department code
      Supporting Biomedical Discovery with the ROBOKOP Graph Knowledgebase.

      Principal investigators: Alexander Tropsha (contact PI), Christopher Bizon

      $786,413
      award amount
  10. Samuel Lai

    Leads 2 awards · $768,383

    • 5R01AI165853-04Department: NIH department code
      Engineered “muco-trapping” antibodies for inhaled therapy of parainfluenza and human metapneumovirus infections

      Principal investigators: Samuel Lai (contact PI), Raymond J Pickles

      $535,133
      award amount
    • 1R21AI185808-01A1Department: NIH department code
      Engineering non-replicating self-recirculating phages as platform for gene therapy of the microbiome
      $233,250
      award amount
  11. David S. Lawrence

    Leads 1 award · $767,077

    • 1R01HL176666-01Department: NIH department code
      Assembly, Dosimetry, and Assessment of a Platform Technology for the Delivery of Thrombolytics
      $767,077
      award amount
  12. Jessica Jillian Walsh

    Leads 1 award · $757,901

    • 5R01MH136266-02Department: NIH department code
      Neural mechanisms underlying sustained enhancement of sociability
      $757,901
      award amount
  13. Kirsten L Bryant

    Leads 1 award · $717,245

    • 4R37CA251877-06Department: NIH department code
      Mechanistic dissection and inhibitor targeting of autophagy in RAS driven cancers
      $717,245
      award amount
  14. Henrik G. Dohlman

    Leads 1 award · $659,119

    • 5R35GM118105-10Department: NIH department code
      Negative and positive feedback in cell signaling
      $659,119
      award amount
  15. Joseph Mauro Calabrese

    Leads 1 award · $624,197

    • 5R35GM153293-02Department: NIH department code
      Mechanisms of gene regulation by long noncoding RNAs
      $624,197
      award amount

    Also a principal investigator on 2T32GM135095-06, led by Michael James Emanuele.

  16. Julie Brumer Dumond

    Leads 1 award · $579,148

    • 5R01AI153007-05Department: NIH department code
      Quantifying Sex-and-Age-Related Differences in Antiretroviral Exposure and Adverse Effects in the MACS/WIHS Combined Cohort Study
      $579,148
      award amount
  17. William C Zamboni

    Leads 1 award · $555,851

    • 5R01CA247652-05Department: NIH department code
      Minibeam Radiation Therapy Enhanced Delivery of Nanoparticle Anticancer Agents to Pancreatic Cancer Tumors

      Principal investigators: William C Zamboni (contact PI), Sha X Chang, Steven K. Libutti

      $555,851
      award amount
  18. Andrew L Lee

    Leads 2 awards · $535,361

    • 5R35GM144348-04Department: NIH department code
      Mechanisms and dynamics of allosteric function in proteins
      $462,164
      award amount
    • 3R35GM144348-04S1Department: NIH department code
      Mechanisms and dynamics of allosteric function in proteins
      $73,197
      award amount
  19. Kristy M Ainslie

    Leads 1 award · $501,011

    • 1R01AI187725-01Department: NIH department code
      Biodegradable polymeric microparticles comprised of acetalated dextran induce immune tolerance
      $501,011
      award amount
  20. Rihe Liu

    Leads 1 award · $473,654

    • 5R01EB032865-04Department: NIH department code
      A Wholly Protein-based Self-assembly Nanoplatform for TNBC-specific Combination Therapy
      $473,654
      award amount
  21. Timothy C Elston

    Leads 1 award · $466,907

    • 5R35GM127145-08Department: NIH department code
      Mathematical modeling of cellular signaling systems
      $466,907
      award amount
  22. Robert McGinty

    Leads 1 award · $461,304

    • 5R35GM133498-07Department: NIH department code
      Molecular Mechanisms of Chromatin Recognition
      $461,304
      award amount
  23. Nicholas Gene Brown

    Leads 1 award · $454,118

    • 5R35GM128855-08Department: NIH department code
      Spindle Assembly Checkpoint Silencing
      $454,118
      award amount
  24. Shawn Hingtgen

    Leads 1 award · $430,654

    • 5R01CA269974-04Department: NIH department code
      Harnessing Continuous Liquid Interface 3D Printing to Improve Tumor-homing Stem Cell Therapy for Post-surgical Brain Cancer

      Principal investigators: Shawn Hingtgen (contact PI), Jillian Perry

      $430,654
      award amount
  25. John E Sondek

    Leads 1 award · $427,684

    • 5R35GM149299-03Department: NIH department code
      Phospholipase C Isozymes
      $427,684
      award amount
  26. Brent Asrican

    Leads 1 award · $426,674

    • 1R21AG091124-01A1Department: NIH department code
      Implications of long-range Mossy Cell signaling and connectivity in AD

      Principal investigators: Brent Asrican (contact PI), Juan Song

      $426,674
      award amount
  27. Yevgeny Brudno

    Leads 1 award · $401,164

    • 5R33CA281875-03Department: NIH department code
      MASTER Scaffolds for Rapid, Single-Step Manufacture and Prototyping of CAR-T cells
      $401,164
      award amount
  28. Alexander V Kabanov

    Leads 1 award · $399,829

    • 1R21CA305031-01Department: NIH department code
      Discovering Fusobacterium nucleatum's Impact on Breast Cancer Progression and Treatment with POx Micelle Technology
      $399,829
      award amount
  29. Albert A Bowers

    Leads 1 award · $389,341

    • 5R35GM125005-09Department: NIH department code
      Chemoenzymatic Synthesis, Mode of Action and Evolution of Natural Product-based Macrocycles
      $389,341
      award amount
  30. Daniel Issac Dominguez

    Leads 1 award · $388,750

    • 5R35GM142864-05Department: NIH department code
      Protein Disorder as a Mechanism of RNA Binding and Regulation
      $388,750
      award amount
  31. Stephen Vernon Frye

    Leads 1 award · $383,255

    • 5R35GM139514-05Department: NIH department code
      PROBING ALLOSTERY IN METHYL-LYSINE READER DOMAINS
      $383,255
      award amount
  32. Owen S Fenton

    Leads 1 award · $381,995

    • 1R35GM157060-01Department: NIH department code
      Investigating and Manipulating Cells in Low Oxygen Environments Using Lipid Nanoparticles
      $381,995
      award amount
  33. Kimberly Ritola

    Leads 1 award · $358,096

    • 5U24NS124025-05Department: NIH department code
      BRAIN Viral Vector Services and Distribution Core
      $358,096
      award amount
  34. Marina Sokolsky-Papkov

    Leads 1 award · $349,875

    • 5R01NS125073-04Department: NIH department code
      Nanoformulated small molecule immunotherapy for SHH medulloblastoma
      $349,875
      award amount
  35. Adam Christopher Palmer

    Leads 1 award · $344,581

    • 5R01CA279968-02Department: NIH department code
      Modeling and analysis of curative combination therapy for Diffuse Large B-Cell Lymphoma
      $344,581
      award amount
  36. Xiaodong Wang

    Leads 1 award · $323,080

    • 5R01CA259077-05Department: NIH department code
      Novel TYRO3 inhibitors for treatment of cancer

      Principal investigators: Xiaodong Wang (contact PI), Douglas K Graham

      $323,080
      award amount
  37. Jeffrey Aube

    Leads 1 award · $273,018

    • 5T32GM135122-05Department: NIH department code
      UNC Chemical Biology Interface Training Program
      $273,018
      award amount
  38. Channing J. Der

    Leads 1 award · $251,339

  39. Laura Brockway Ferguson

    Leads 1 award · $248,844

    • 4R00AA030821-03Department: NIH department code
      RNA biomarkers for alcohol use disorder
      $248,844
      award amount
  40. Robert A Nicholas

    Leads 1 award · $194,375

    • 5R21AI180668-02Department: NIH department code
      Modulation of immune responses mediated by PorB from Neisseria gonorrhoeae

      Principal investigators: Robert A Nicholas (contact PI), Joseph A Duncan

      $194,375
      award amount
  41. Anthony M Downs

    Leads 1 award · $184,706

    • 1K01DA061050-01A1Department: NIH department code
      Impact of fentanyl consumption on noradrenergic plasticity in the basolateral amygdala
      $184,706
      award amount
  42. Leon Garland Coleman

    Leads 1 award · $184,656

    • 5R21AA031414-02Department: NIH department code
      3D Human neurocircuits to determine the role of microglia in AUD and Alzheimer's neuronal pathology

      Principal investigators: Leon Garland Coleman (contact PI), Jeffrey M. MacDonald

      $184,656
      award amount

    Also a principal investigator on 5R25NS130653-02, led by Jonathan C. Schisler.

  43. Jonathan C. Schisler

    Leads 1 award · $135,000

  44. Brianna Elyse George

    Leads 1 award · $78,796

    • 5K00AA031604-03Department: NIH department code
      Early-Life Stress Drives Increased Heroin Vulnerability: Role of D3 Receptors
      $78,796
      award amount
  45. Jonathan M Ellis

    Leads 1 award · $73,828

    • 1F32GM157944-01Department: NIH department code
      Engineering and application of modular chimeric tRNA synthetases in mRNA display
      $73,828
      award amount
  46. McKenzie Murvin

    Leads 1 award · $42,798

    • 5F31HD111292-03Department: NIH department code
      Dissecting mechanisms of gene silencing by the lncRNA Kcnq1ot1 in mouse trophoblast stem cells
      $42,798
      award amount
  47. Amy Aponte

    Leads 1 award · $40,752

    • 5F31CA288070-02Department: NIH department code
      Regulation of the retinoblastoma (Rb) tumor suppressor by the ubiquitin-proteasome system
      $40,752
      award amount
  48. Quinn Elise Eberhard

    Leads 1 award · $40,628

    • 1F31HG014413-01Department: NIH department code
      Computational tools to study relationships between sequence, structure, and function in lncRNAs
      $40,628
      award amount
  49. Ryan Robb

    Leads 1 award · $40,628

    • 5F31CA284869-02Department: NIH department code
      Mechanistic examination and inhibitor targeting of nutrient scavenging for the treatment of pancreatic cancer
      $40,628
      award amount
  50. Michael Sean Sturdivant

    Leads 1 award · $39,407

    • 5F31CA281339-02Department: NIH department code
      The Mutagenic Effects of APOBEC3A and APOBEC3B in Urothelial Carcinoma
      $39,407
      award amount
  51. Megan C. Roberts

    Leads 1 award · $23,000

    • 5R13CA261073-04Department: NIH department code
      Transdisciplinary Conference for Future Leaders in Precision Public Health

      Principal investigators: Megan C. Roberts (contact PI), Caitlin Gloeckner Allen

      $23,000
      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.