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FY2024 NIH awards · Principal investigators

Pharmacology at University of North Carolina at Chapel Hill

Chapel Hill, NC

Funding
$32.2M
$32,165,064
Awards
83
FY2024 NIH awards in Pharmacology
Principal investigators
79
58 lead a grant here, 21 co-investigators
Department rank
#4
of 139 · Ranking
  • NIH names only the principal investigators on an award, so this page lists only them. The department is the award's: it is where ScienceDex counts the award, not a list of the department's members.
  • These are the awards in the Pharmacology row of the University of North Carolina at Chapel Hill page.

Leads a grant in this department

58 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

  1. Juan Song

    Leads 5 awards · $3,094,026

    • 5R01MH132222-02Department: NIH department code
      Regulation and functional contribution of hypothalamic modified adult hippocampal neurogenesis
      $747,199
      award amount
    • 5R01AG084207-02Department: NIH department code
      Enhancing adult-born neurons to restore brain functions in Alzheimer's disease
      $714,945
      award amount
    • 4R01AG071000-02Department: NIH department code
      Glutamatergic neural circuit modulation for treating Alzheimer’s disease
      $599,462
      award amount
    • 5R01MH122692-05Department: NIH department code
      Sex-dependent role of 5HT1A receptors in adult neurogenesis and hippocampal function
      $571,019
      award amount
    • 5R01NS121300-04Department: NIH department code
      Role of Cholecystokinin in the Dentate Gyrus
      $461,401
      award amount

  2. Bryan L. Roth

    Leads 3 awards · $1,819,764

    • 5R37DA045657-07Department: NIH department code
      Mechanistic insights into LSD actions at 5-HT2A serotonin receptors
      $650,756
      award amount
    • 5R01MH112205-08Department: NIH department code
      Molecular Details of Psychoactive Drug Actions

      Principal investigators: Bryan L. Roth (contact PI), Brian K Shoichet

      $605,561
      award amount
    • 5R01DA055656-03Department: NIH department code
      STRUCTURE AND FUNCTION OF MRG-FAMILY RECEPTORS

      Principal investigators: Bryan L. Roth (contact PI), Brian K Shoichet

      $563,447
      award amount

  3. Shawn Hingtgen

    Leads 2 awards · $1,527,323

    • 5U01TR003715-04Department: NIH department code
      A consortium effort to translate therapies for neurological diseases via an ex vivo organotypic platform

      Principal investigators: Shawn Hingtgen (contact PI), Albert Sidney Baldwin, Catherine T Flores, Scott R Floyd

      $1,117,537
      award amount
    • 5R01CA269974-03Department: NIH department code
      Harnessing Continuous Liquid Interface 3D Printing to Improve Tumor-homing Stem Cell Therapy for Post-surgical Brain Cancer

      Principal investigators: Shawn Hingtgen (contact PI), Jillian Perry

      $409,786
      award amount

  4. Juliane Nguyen

    Leads 3 awards · $1,512,206

    • 1R01HL174038-01Department: NIH department code
      Maximizing Therapeutic Accumulation and Retention for Enhanced Cardiac Repair
      $706,718
      award amount
    • 5R01HL161456-03Department: NIH department code
      Engineering a cross-linked cellular network for cardiac repair
      $471,130
      award amount
    • 5R01CA241679-05Department: NIH department code
      Polarizing Macrophages to Tumor Suppressors by Blocking Multiple CCR2 Chemokine Receptor Epitopes
      $334,358
      award amount

  5. Thomas L. Kash

    Leads 3 awards · $1,346,987

    • 2R01AA019454-13A1Department: NIH department code
      Extended Amygdala Regulation of Dorsal Raphe Function in Ethanol Self-Administration
      $524,936
      award amount
    • 1R01AA031450-01Department: NIH department code
      Probing Ethanol Dysregulation of Hypothalamic CRH neurons

      Principal investigators: Thomas L. Kash (contact PI), Jaideep Bains

      $438,539
      award amount
    • 5R01NS122230-04Department: NIH department code
      Determining the impact of BNST CRF systems on inflammatory pain-induced disruptions of behavior
      $383,512
      award amount

  6. Michael James Emanuele

    Leads 3 awards · $1,320,472

    • 1R35GM153250-01Department: NIH department code
      Proteostasis signaling in cell cycle control
      $581,533
      award amount
    • 5T32GM135095-05Department: NIH department code
      Predoctoral Training in the Pharmacological Sciences

      Principal investigators: Michael James Emanuele (contact PI), Joseph Mauro Calabrese

      $549,359
      award amount
    • 3R35GM153250-01S1Department: NIH department code
      Proteostasis signaling in cell cycle control
      $189,580
      award amount

  7. Channing J. Der

    Leads 2 awards · $1,198,512

    • 5R35CA232113-07Department: NIH department code
      Targeting undruggable RAS for cancer treatment
      $865,656
      award amount
    • 5T32CA071341-27Department: NIH department code
      Cancer Cell Biology Training Program

      Principal investigators: Channing J. Der (contact PI), Adrienne D Cox

      $332,856
      award amount

  8. Fulton T Crews

    Leads 2 awards · $1,057,771

    • 5U01AA020023-15Department: NIH department code
      5/8 NADIA U01 Effects of Adolescent Alcohol on adult brain Neurocircuitry
      $570,876
      award amount
    • 5U24AA020024-15Department: NIH department code
      1/1 NADIA U24 Administrative Core
      $486,895
      award amount

    Also a principal investigator on 5R01AA028924-05, led by Leon Garland Coleman.

  9. Jeffrey Aube

    Leads 2 awards · $1,051,961

    • 5R01AI155510-04Department: NIH department code
      Discovery of Phospopantetheinyl Transferse Inhibitors Against Mycobacterium tuberculosis
      $770,597
      award amount
    • 5T32GM135122-04Department: NIH department code
      UNC Chemical Biology Interface Training Program
      $281,364
      award amount

  10. Erin L Heinzen

    Leads 2 awards · $815,971

    • 5R01NS115017-05Department: NIH department code
      Defining disease mechanisms in SLC35A2 epilepsy

      Principal investigators: Erin L Heinzen (contact PI), Peter B Crino

      $667,685
      award amount
    • 3R01NS115017-04S1Department: NIH department code
      Defining disease mechanisms in SLC35A2 epilepsy

      Principal investigators: Erin L Heinzen (contact PI), Peter B Crino

      $148,286
      award amount

  11. Klaus M. Hahn

    Leads 1 award · $810,270

    • 5R35GM122596-08Department: NIH department code
      Dissecting signaling in vivo via precise control and visualization of protein activity
      $810,270
      award amount

  12. Samuel Lai

    Leads 2 awards · $798,803

    • 5R01AI165853-03Department: NIH department code
      Engineered “muco-trapping” antibodies for inhaled therapy of parainfluenza and human metapneumovirus infections

      Principal investigators: Samuel Lai (contact PI), Raymond J Pickles

      $629,240
      award amount
    • 5R21CA273983-02Department: NIH department code
      Engineering Siglec15/TGF-beta targeted bispecific antibodies that modulate the tumor microenvironment and enhances T-cell immunotherapy against pancreatic cancer
      $169,563
      award amount

  13. Alexander Tropsha

    Leads 1 award · $787,035

    • 5U24ES035214-03Department: NIH department code
      Supporting Biomedical Discovery with the ROBOKOP Graph Knowledgebase.

      Principal investigators: Alexander Tropsha (contact PI), Christopher Bizon

      $787,035
      award amount

  14. Xiaodong Wang

    Leads 2 awards · $770,193

    • 5R01CA249190-05Department: NIH department code
      MERTK/AXL dual inhibitors provide novel treatment for cancer by targeting tumor cells and activating anti-tumor immunity

      Principal investigators: Xiaodong Wang (contact PI), Douglas K Graham

      $463,267
      award amount
    • 5R01CA259077-04Department: NIH department code
      Novel TYRO3 inhibitors for treatment of cancer

      Principal investigators: Xiaodong Wang (contact PI), Douglas K Graham

      $306,926
      award amount

  15. Jessica Jillian Walsh

    Leads 1 award · $757,002

    • 1R01MH136266-01Department: NIH department code
      Neural mechanisms underlying sustained enhancement of sociability
      $757,002
      award amount

  16. David S. Lawrence

    Leads 1 award · $687,920

    • 5R01HL153744-04Department: NIH department code
      Design and Application of Photoresponsive Modules in Circulating Erythrocytes
      $687,920
      award amount

  17. Henrik G. Dohlman

    Leads 1 award · $659,119

    • 5R35GM118105-09Department: NIH department code
      Negative and positive feedback in cell signaling
      $659,119
      award amount

  18. Joseph Mauro Calabrese

    Leads 1 award · $629,698

    • 1R35GM153293-01Department: NIH department code
      Mechanisms of gene regulation by long noncoding RNAs
      $629,698
      award amount

    Also a principal investigator on 5T32GM135095-05, led by Michael James Emanuele.

  19. Jonathan C. Schisler

    Leads 3 awards · $623,497

    • 5R01AG066710-05Department: NIH department code
      Protein quality control in age-related diseases
      $447,532
      award amount
    • 1R25NS130653-01A1Department: NIH department code
      CAROLINA SUMMER FELLOWS PROGRAM IN NEUROPHARMACOLOGY AND NEUROBIOLOGICAL DISEASES (CSF-NEURO)

      Principal investigators: Jonathan C. Schisler (contact PI), Benjamin D Philpot, Leon Garland Coleman

      $135,000
      award amount
    • 3R01AG066710-05S1Department: NIH department code
      Protein quality control in age-related diseases
      $40,965
      award amount

  20. Julie Brumer Dumond

    Leads 1 award · $621,756

    • 5R01AI153007-04Department: NIH department code
      Quantifying Sex-and-Age-Related Differences in Antiretroviral Exposure and Adverse Effects in the MACS/WIHS Combined Cohort Study
      $621,756
      award amount

  21. Leon Garland Coleman

    Leads 2 awards · $612,281

    • 5R01AA028924-05Department: NIH department code
      Microglia Activation and TLR-induced Neurodegeneration by Alcohol Promotes Progression of Alzheimer Pathology

      Principal investigators: Leon Garland Coleman (contact PI), Fulton T Crews

      $388,750
      award amount
    • 1R21AA031414-01A1Department: NIH department code
      3D Human neurocircuits to determine the role of microglia in AUD and Alzheimer's neuronal pathology

      Principal investigators: Leon Garland Coleman (contact PI), Jeffrey M. MacDonald

      $223,531
      award amount

    Also a principal investigator on 1R25NS130653-01A1, led by Jonathan C. Schisler.

  22. Alexander V Kabanov

    Leads 1 award · $582,405

    • 5R01CA264488-04Department: NIH department code
      TOWARD TRANSLATION OF NANFORMULATED PACLITAXEL-PLATINUM COMBINATION
      $582,405
      award amount

  23. Andrew L Lee

    Leads 4 awards · $576,033

    • 5R35GM144348-03Department: NIH department code
      Mechanisms and dynamics of allosteric function in proteins
      $462,164
      award amount
    • 3R35GM144348-03S1Department: NIH department code
      Mechanisms and dynamics of allosteric function in proteins
      $87,839
      award amount
    • 3R35GM144348-02S1Department: NIH department code
      Mechanisms and dynamics of allosteric function in proteins
      $14,642
      award amount
    • 3R35GM144348-03S2Department: NIH department code
      Mechanisms and dynamics of allosteric function in proteins
      $11,388
      award amount

  24. Kristy M Ainslie

    Leads 1 award · $553,436

    • 5R01AI147497-05Department: NIH department code
      Optimizing a Universal Influenza Subunit Nano/Microparticulate Vaccine
      $553,436
      award amount

  25. William C Zamboni

    Leads 1 award · $528,058

    • 5R01CA247652-04Department: NIH department code
      Minibeam Radiation Therapy Enhanced Delivery of Nanoparticle Anticancer Agents to Pancreatic Cancer Tumors

      Principal investigators: William C Zamboni (contact PI), Sha X Chang, Steven K. Libutti

      $528,058
      award amount

  26. Timothy C Elston

    Leads 1 award · $466,907

    • 5R35GM127145-07Department: NIH department code
      Mathematical modeling of cellular signaling systems
      $466,907
      award amount

  27. Rihe Liu

    Leads 1 award · $464,182

    • 5R01EB032865-03Department: NIH department code
      A Wholly Protein-based Self-assembly Nanoplatform for TNBC-specific Combination Therapy
      $464,182
      award amount

  28. Robert McGinty

    Leads 1 award · $461,304

    • 2R35GM133498-06Department: NIH department code
      Molecular Mechanisms of Chromatin Recognition
      $461,304
      award amount

  29. Nicholas Gene Brown

    Leads 1 award · $454,118

    • 5R35GM128855-07Department: NIH department code
      Spindle Assembly Checkpoint Silencing
      $454,118
      award amount

  30. John E Sondek

    Leads 1 award · $427,684

    • 5R35GM149299-02Department: NIH department code
      Phospholipase C Isozymes
      $427,684
      award amount

  31. Stephen Vernon Frye

    Leads 1 award · $425,839

    • 5R35GM139514-04Department: NIH department code
      PROBING ALLOSTERY IN METHYL-LYSINE READER DOMAINS
      $425,839
      award amount

  32. Samantha Gail Pattenden

    Leads 1 award · $400,467

    • 5R01GM138912-04Department: NIH department code
      Development of a cavitation enhancement technology to access archived tissues for epigenetic-based biomedical research

      Principal investigators: Samantha Gail Pattenden (contact PI), Ian J Davis

      $400,467
      award amount

  33. Albert A Bowers

    Leads 1 award · $389,341

    • 5R35GM125005-08Department: NIH department code
      Chemoenzymatic Synthesis, Mode of Action and Evolution of Natural Product-based Macrocycles
      $389,341
      award amount

  34. Daniel Issac Dominguez

    Leads 1 award · $388,750

    • 5R35GM142864-04Department: NIH department code
      Protein Disorder as a Mechanism of RNA Binding and Regulation
      $388,750
      award amount

  35. Richard J Samulski

    Leads 1 award · $388,750

    • 5R01HL151348-04Department: NIH department code
      Development of AAV vectors for CF therapy

      Principal investigators: Richard J Samulski (contact PI), Chengwen Li

      $388,750
      award amount

  36. Maria M. Aleman

    Leads 1 award · $378,446

    • 5R01DK124773-05Department: NIH department code
      Iron-sensitive RNA regulation during erythropoiesis
      $378,446
      award amount

  37. Marina Sokolsky-Papkov

    Leads 1 award · $377,088

    • 5R01NS125073-03Department: NIH department code
      Nanoformulated small molecule immunotherapy for SHH medulloblastoma
      $377,088
      award amount

  38. Kimberly Ritola

    Leads 1 award · $369,593

    • 5U24NS124025-04Department: NIH department code
      BRAIN Viral Vector Services and Distribution Core
      $369,593
      award amount

  39. Adam Christopher Palmer

    Leads 1 award · $344,581

    • 1R01CA279968-01A1Department: NIH department code
      Modeling and analysis of curative combination therapy for Diffuse Large B-Cell Lymphoma
      $344,581
      award amount

  40. Kirsten L Bryant

    Leads 1 award · $306,070

    • 5R37CA251877-05Department: NIH department code
      Mechanistic dissection and inhibitor targeting of autophagy in RAS driven cancers
      $306,070
      award amount

  41. Robert A Nicholas

    Leads 1 award · $218,503

    • 1R21AI180668-01A1Department: NIH department code
      Modulation of immune responses mediated by PorB from Neisseria gonorrhoeae

      Principal investigators: Robert A Nicholas (contact PI), Joseph A Duncan

      $218,503
      award amount

  42. Yevgeny Brudno

    Leads 1 award · $199,164

    • 7R21CA277018-02Department: NIH department code
      Biomaterial Scaffolds for In Vivo CAR T Cell Manufacture
      $199,164
      award amount

  43. Lindsey Ingerman James

    Leads 1 award · $138,700

    • 5R01CA242305-06Department: NIH department code
      DISCOVERY OF FIRST-IN-CLASS NSD2 DEGRADERS FOR CANCER THERAPY
      $138,700
      award amount

  44. Jennifer E Klomp

    Leads 1 award · $111,438

    • 5K99CA276700-02Department: NIH department code
      Mechanistic Basis for ERK in driving KRAS-dependent pancreatic cancer
      $111,438
      award amount

  45. Meghan Elizabeth Flanigan

    Leads 1 award · $104,106

    • 5K99AA030628-02Department: NIH department code
      Regulation of alcohol-induced social disturbances by lateral habenula serotonin receptors
      $104,106
      award amount

  46. Daniel Dewran Kocak

    Leads 1 award · $98,161

    • 5K99GM149931-02Department: NIH department code
      DRUG DISCOVERY BY DIRECTED EVOLUTION IN MAMMALIAN CELLS
      $98,161
      award amount

  47. Brianna Elyse George

    Leads 1 award · $78,796

    • 8K00AA031604-02Department: NIH department code
      Early-Life Stress Drives Increased Heroin Vulnerability: Role of D3 Receptors
      $78,796
      award amount

  48. Kevin Pruitt

    Leads 1 award · $77,750

    • 5R03AG080356-03Department: NIH department code
      Post-translational regulation of aromatase in aging
      $77,750
      award amount

  49. Victoria Alice Macht

    Leads 1 award · $48,070

    • 3K99AA030089-02S1Department: NIH department code
      Supplement: Adolescent intermittent ethanol induction of neuroimmune signaling disrupts the mature phenotype of surviving hippocampal neuroprogenitors
      $48,070
      award amount

  50. McKenzie Murvin

    Leads 1 award · $42,234

    • 5F31HD111292-02Department: NIH department code
      Dissecting mechanisms of gene silencing by the lncRNA Kcnq1ot1 in mouse trophoblast stem cells
      $42,234
      award amount

  51. Tania Jazmine Bellinger

    Leads 1 award · $40,441

    • 1F31DA060688-01Department: NIH department code
      Structural and functional responses of nucleus accumbens microglia following long-access cocaine self-administration
      $40,441
      award amount

  52. Amy Aponte

    Leads 1 award · $40,188

    • 1F31CA288070-01Department: NIH department code
      Regulation of the retinoblastoma (Rb) tumor suppressor by the ubiquitin-proteasome system
      $40,188
      award amount

  53. Elizabeth Abrash

    Leads 1 award · $40,064

    • 1F31HD114456-01A1Department: NIH department code
      Decoding Repression: Recruitment of epigenetic silencers by RNA binding proteins and long non-coding RNAs
      $40,064
      award amount

  54. Ryan Robb

    Leads 1 award · $40,064

    • 1F31CA284869-01A1Department: NIH department code
      Mechanistic examination and inhibitor targeting of nutrient scavenging for the treatment of pancreatic cancer
      $40,064
      award amount

  55. Michael Sean Sturdivant

    Leads 1 award · $35,843

    • 1F31CA281339-01A1Department: NIH department code
      The Mutagenic Effects of APOBEC3A and APOBEC3B in Urothelial Carcinoma
      $35,843
      award amount

  56. Megan C. Roberts

    Leads 1 award · $33,000

    • 5R13CA261073-03Department: NIH department code
      Transdisciplinary Conference for Future Leaders in Precision Public Health

      Principal investigators: Megan C. Roberts (contact PI), Caitlin Gloeckner Allen

      $33,000
      award amount

  57. Madigan Bedard

    Leads 1 award · $32,922

    • 5F31DA056211-02Department: NIH department code
      GABAergic alterations in the BNST to VTA circuit following morphine withdrawal
      $32,922
      award amount

  58. Kim L.r. Brouwer

    Leads 1 award · $1

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.