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FY2025 NIH awards · Principal investigators

Physiology at University of North Carolina at Chapel Hill

Chapel Hill, NC

Funding
$26.1M
$26,144,050
Awards
61
FY2025 NIH awards in Physiology
Principal investigators
56
39 lead a grant here, 17 co-investigators
Department rank
#1
of 86 · Ranking
  • NIH names only the principal investigators on an award, so this page lists only them. The department is the award's: it is where ScienceDex counts the award, not a list of the department's members.
  • These are the awards in the Physiology row of the University of North Carolina at Chapel Hill page.

Leads a grant in this department

39 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

  1. Mark J. Zylka

    Leads 5 awards · $3,679,454

    • 1UG3NS137515-01A1Department: NIH department code
      Genome editor therapy for Angelman syndrome
      $1,508,248
      award amount
    • 5R35ES028366-07Department: NIH department code
      Environmental-use chemicals that target pathways linked to autism and other neurodevelopmental disorders
      $852,030
      award amount
    • 1R01NS144331-01Department: NIH department code
      Targeted high-fidelity integration of DNA elements into the genome
      $603,457
      award amount
    • 5T32NS007431-27Department: NIH department code
      Neuroscience Predoctoral Training at UNC-Chapel Hill

      Principal investigators: Mark J. Zylka (contact PI), Juan Song

      $482,469
      award amount
    • 1R21NS142886-01Department: NIH department code
      Luminescence-based biosensor to non-invasively measure UBE3A activity in the brain
      $233,250
      award amount

  2. Mohanish P Deshmukh

    Leads 5 awards · $3,010,823

    • 5T32GM152316-02Department: NIH department code
      UNC Medical Scientist Training Program

      Principal investigators: Mohanish P Deshmukh (contact PI), Toni Darville

      $1,399,081
      award amount
    • 5R01AG082140-03Department: NIH department code
      miR-29: A brain homeostasis molecule for Alzheimer’s disease prevention
      $620,826
      award amount
    • 5R01NS117133-03Department: NIH department code
      Unexpected Function of Inflammasomes in Axon Pruning: Focus on NLRP1
      $547,528
      award amount
    • 5R01NS122399-05Department: NIH department code
      Spatial Restriction of Apoptotic Machinery during Neuronal Apoptosis and Pruning
      $382,843
      award amount
    • 3T32GM152316-02S1Department: NIH department code
      UNC Medical Scientist Training Program

      Principal investigators: Mohanish P Deshmukh (contact PI), Toni Darville

      $60,545
      award amount

  3. Eva S Anton

    Leads 3 awards · $2,865,991

    • 4RF1MH132710-04Department: NIH department code
      Primary Cilia: A Novel Signaling Gateway To Neural Circuit Modulation

      Principal investigators: Eva S Anton (contact PI), Jeff W Lichtman, Ryohei Yasuda

      $2,189,936
      award amount
    • 5R35NS116859-06Department: NIH department code
      DEFINING MECHANISMS OF PROGENITOR BALANCE AND NEURONAL CONNECTIVITY
      $544,250
      award amount
    • 3R35NS116859-06S1Department: NIH department code
      DEFINING MECHANISMS OF PROGENITOR BALANCE AND NEURONAL CONNECTIVITY
      $131,805
      award amount

  4. Benjamin D Philpot

    Leads 3 awards · $1,472,483

    • 5R01NS131615-03Department: NIH department code
      Small Molecule Therapeutic Discovery for Angelman Syndrome

      Principal investigators: Benjamin D Philpot (contact PI), Jeffrey Aube

      $575,490
      award amount
    • 5T32HD040127-24Department: NIH department code
      Postdoctoral Research in Neurodevelopmental Disorders

      Principal investigators: Benjamin D Philpot (contact PI), Mark D Shen

      $533,062
      award amount
    • 5R01NS129914-03Department: NIH department code
      Investigating UBE3A as a driver gene in Duplication 15q syndrome
      $363,931
      award amount

  5. Gregory Scherrer

    Leads 1 award · $1,397,859

    • 5R01DA054583-05Department: NIH department code
      A comprehensive dissection of cell types, circuits and molecular adaptations during opioid use

      Principal investigators: Gregory Scherrer (contact PI), Hongkui Zeng, Mark J Schnitzer

      $1,397,859
      award amount

  6. Michael C Bressan

    Leads 2 awards · $1,270,459

    • 1R01HL175577-01A1Department: NIH department code
      "Outside-in” Model of Cardiac Pacemaking: Extracellular Mediated Automaticity

      Principal investigators: Michael C Bressan (contact PI), Steven Poelzing

      $668,783
      award amount
    • 5R01HL146626-07Department: NIH department code
      Regulation of cardiac pacemaker cell cytoarchitecture
      $601,676
      award amount

  7. Scott Parnell

    Leads 2 awards · $1,164,291

    • 5R01AA026068-07Department: NIH department code
      Cellular Mechanisms in Fetal Alcohol Spectrum Disorders

      Principal investigators: Scott Parnell (contact PI), Kevin Peter Williams

      $625,123
      award amount
    • 5R01AA031346-03Department: NIH department code
      Characterizing the Genetics of FASD in Complementary Mouse and Fish Models

      Principal investigators: Scott Parnell (contact PI), Johann K Eberhart, Lisa M Tarantino

      $539,168
      award amount

  8. Lori L O'Brien

    Leads 2 awards · $1,088,514

    • 2R01DK121014-06A1Department: NIH department code
      Trophic interactions directing proper kidney development
      $660,889
      award amount
    • 1R21HD117223-01Department: NIH department code
      Redefining kidney developmental origins
      $427,625
      award amount

  9. Adam Hantman

    Leads 2 awards · $1,007,970

    • 1R01NS145518-01Department: NIH department code
      Causally linking UBE3A misexpression to altered circuit dynamics controlling skilled movements

      Principal investigators: Adam Hantman (contact PI), Matthew Charles Judson

      $587,904
      award amount
    • 5R01NS118030-04Department: NIH department code
      Deconstructing the roles of basal ganglia and cerebellum-related thalamic inputs to motor cortex during control of dexterous behavior
      $420,066
      award amount

  10. Sarah Cohen

    Leads 2 awards · $981,606

    • 5R01AG081421-03Department: NIH department code
      Assessing the role of APOE in glial lipid droplet metabolism and function

      Principal investigators: Sarah Cohen (contact PI), Lance Allen Johnson

      $560,263
      award amount
    • 2R35GM133460-06Department: NIH department code
      Composition and Function of Membrane Contact Sites in Differentiation and Disease
      $421,343
      award amount

  11. Graham Hugh Diering

    Leads 2 awards · $914,421

    • 5R01AG068063-03Department: NIH department code
      Sleep-dependent synaptic homeostasis in Alzheimer's disease

      Principal investigators: Graham Hugh Diering (contact PI), Todd Jonathan Cohen

      $688,115
      award amount
    • 5R21MH135250-02Department: NIH department code
      Developmental sleep disruption interacts with underlying CHD8 genetic vulnerability in autism spectrum disorder
      $226,306
      award amount

  12. Douglas H. Phanstiel

    Leads 2 awards · $905,845

    • 5R35GM128645-07Department: NIH department code
      Mechanisms and impacts of chromatin looping
      $456,600
      award amount
    • 5R01AR079538-04Department: NIH department code
      Identifying novel osteoarthritis risk genes using GWAS, chondrocyte genomics, and genome editing

      Principal investigators: Douglas H. Phanstiel (contact PI), Richard F Loeser

      $449,245
      award amount

  13. Stephanie Gupton

    Leads 2 awards · $856,791

    • 2R35GM135160-06Department: NIH department code
      Coordinated Cytoskeletal Dynamics and Membrane Remodeling in Cellular Shape Change
      $443,311
      award amount
    • 1R21NS144608-01Department: NIH department code
      Defining the Substrates and Interactome of Focal Adhesion Kinase that Regulate Exocytic Vesicle Fusion
      $413,480
      award amount

  14. Kathleen M Caron

    Leads 2 awards · $632,235

    • 5R01HD060860-13Department: NIH department code
      Adrenomedullin Signaling at the Maternal-Fetal Interface
      $419,055
      award amount
    • 2T32GM133364-06Department: NIH department code
      Training Program in Cellular Systems and Integrative Physiology

      Principal investigators: Kathleen M Caron (contact PI), Natasha T Snider

      $213,180
      award amount

  15. James E Bear

    Leads 1 award · $588,330

    • 5R35GM130312-07Department: NIH department code
      Systematic Analysis of the Actin Cytoskeleton and Directed Cell Migration
      $588,330
      award amount

  16. Jessica E Thaxton

    Leads 1 award · $496,391

    • 1R01CA288976-01A1Department: NIH department code
      Manipulating Lipid Metabolism to Reverse Immune Dysfunction in Solid Cancers
      $496,391
      award amount

  17. Natasha T Snider

    Leads 1 award · $479,397

    • 1R01NS136621-01A1Department: NIH department code
      Regenerative Strategies Targeting Retinoic Acid Signaling in Giant Axonal Neuropathy

      Principal investigators: Natasha T Snider (contact PI), Diane Armao

      $479,397
      award amount

    Also a principal investigator on 2T32GM133364-06, led by Kathleen M Caron.

  18. Patrick J Brennwald

    Leads 1 award · $457,456

    • 2R01GM054712-27A1Department: NIH department code
      Polarized Exocytosis: Rabs, Tethers, and SNAREs
      $457,456
      award amount

  19. Robert Houston Dowen

    Leads 1 award · $422,076

    • 2R35GM137985-06Department: NIH department code
      Developmental and nutritional regulation of lipid metabolism
      $422,076
      award amount

  20. Douglas M Cyr

    Leads 1 award · $410,708

    • 5R01GM151501-03Department: NIH department code
      Hsp40 and Hsp70 in Membrane Protein Triage
      $410,708
      award amount

  21. Adam David Gracz

    Leads 1 award · $388,748

    • 7R35GM142503-06Department: NIH department code
      Chromatin regulation of epithelial stem cell function
      $388,748
      award amount

  22. Jimena Giudice

    Leads 1 award · $383,755

    • 5R35GM152426-02Department: NIH department code
      When alternative splicing meets cytoskeleton organization, local translation, and transcription regulation
      $383,755
      award amount

  23. Adrien Tassou

    Leads 1 award · $222,758

    • 1K99NS138387-01A1Department: NIH department code
      Disentangling the specific contributions of different dorsal root ganglia neuron types to pain representation in the brain.
      $222,758
      award amount

  24. Hokyung Kay Chung

    Leads 1 award · $159,840

    • 5K01EB034321-03Department: NIH department code
      Next-generation T cell therapy: SMARTER T cells for enhanced and durable anti-tumor immunity
      $159,840
      award amount

  25. Heather A McCauley

    Leads 1 award · $158,485

    • 5K01DK125341-05Department: NIH department code
      Enteroendocrine Regulation of Intestinal Metabolism
      $158,485
      award amount

  26. Ukrae Cho

    Leads 1 award · $125,683

    • 5K01AR080828-04Department: NIH department code
      Caspase-mediated nuclear pore complex trimming in myogenesis and muscular dystrophies
      $125,683
      award amount

  27. Jesse Niehaus

    Leads 1 award · $80,224

    • 5F32DA057779-03Department: NIH department code
      Characterizing the connectivity and molecular composition of opioid-sensitive neurons in the periaqueductal gray
      $80,224
      award amount

  28. Jessica Leigh Cote

    Leads 1 award · $76,756

    • 5F32AR084326-02Department: NIH department code
      Clathrin alternative splicing in skeletal muscle development
      $76,756
      award amount

  29. Udodirim Onwubiko

    Leads 1 award · $75,520

    • 1F32HD117621-01Department: NIH department code
      Defining the contributions of apoptosis to germline syncytium function during oogenesis
      $75,520
      award amount

  30. Samantha Ella Ryken

    Leads 1 award · $49,538

    • 1F31NS141456-01A1Department: NIH department code
      Defining the regulation of exocytosis in developing neurons
      $49,538
      award amount

  31. Nicholas W Ringelberg

    Leads 1 award · $47,920

    • 5F30HD111296-02Department: NIH department code
      Neural Circuit Mechanisms of Seizure Susceptibility in a Mouse Model of Angelman Syndrome
      $47,920
      award amount

  32. Nicole Elise Ochandarena

    Leads 1 award · $45,650

    • 5F30DA057839-03Department: NIH department code
      Circuit mechanisms for opioid analgesia and addiction in prefrontal cortex
      $45,650
      award amount

  33. Kimberly Lukasik

    Leads 2 awards · $43,143

    • 5F99CA294269-02Department: NIH department code
      The interface of neurons and cancer
      $40,143
      award amount
    • 3F99CA294269-01S1Department: NIH department code
      The interface of neurons and cancer
      $3,000
      award amount

  34. Emily Claire Bulik-Sullivan

    Leads 1 award · $41,184

    • 5F30HL172628-02Department: NIH department code
      Therapeutic potential of CC-90009 for cystic fibrosis
      $41,184
      award amount

  35. Keith Breau

    Leads 1 award · $40,982

    • 5F31DK136305-03Department: NIH department code
      Investigating a role for Wnt-associated planar polarity in collective migration of human intestinal epithelium
      $40,982
      award amount

  36. Christina So

    Leads 1 award · $40,628

    • 5F31HL176142-02Department: NIH department code
      Mechanism of Intracellular ANGPTL3 and ANGPTL8 Trafficking
      $40,628
      award amount

  37. Joseph Krzeski

    Leads 1 award · $40,628

    • 5F31NS139445-02Department: NIH department code
      The Role of UBE3A Isoforms in AS-associated Seizure Susceptibility
      $40,628
      award amount

  38. Reginald James Edwards

    Leads 1 award · $19,507

    • 5F31NS129292-03Department: NIH department code
      Molecular mechanisms of spectrin-dependent axonal organization and function in cerebellar granule cells
      $19,507
      award amount

  39. Toshihide Hige

    Leads 1 award · $1

    • 5R01DC018874-05Department: NIH department code
      Molecular and circuit mechanisms of learning supported by heterogeneous dopaminergic neurons
      $1
      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.