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FY2026 NIH awards · Principal investigators

Physiology at University of North Carolina at Chapel Hill

Chapel Hill, NC

Funding
$25.9M
$25,921,159
Awards
63
FY2026 NIH awards in Physiology
Principal investigators
56
41 lead a grant here, 15 co-investigators
Department rank
#1
of 89 · Ranking
  • NIH names only the principal investigators on an award, so this page lists only them. The department is the award's: it is where ScienceDex counts the award, not a list of the department's members.
  • These are the awards in the Physiology row of the University of North Carolina at Chapel Hill page.

Leads a grant in this department

41 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

  1. Kathleen M Caron

    Leads 3 awards · $3,311,668

    • 1R01HL176992-01A1Department: NIH department code
      Allostery of RAMP-CLR Signaling in Vascular Cells During Migraine
      $2,676,945
      award amount
    • 5R01HD060860-14Department: NIH department code
      Adrenomedullin Signaling at the Maternal-Fetal Interface
      $419,055
      award amount
    • 5T32GM133364-07Department: NIH department code
      Training Program in Cellular Systems and Integrative Physiology

      Principal investigators: Kathleen M Caron (contact PI), Natasha T Snider

      $215,668
      award amount

  2. Mark J. Zylka

    Leads 6 awards · $2,761,412

    • 5R35ES028366-08Department: NIH department code
      Environmental-use chemicals that target pathways linked to autism and other neurodevelopmental disorders
      $852,030
      award amount
    • 1R01NS148408-01Department: NIH department code
      UBE3A mosaicism and its relationship to Angelman syndrome phenotypes
      $615,286
      award amount
    • 5R01NS144331-02Department: NIH department code
      Targeted high-fidelity integration of DNA elements into the genome
      $609,019
      award amount
    • 5T32NS007431-28Department: NIH department code
      Neuroscience Predoctoral Training at UNC-Chapel Hill

      Principal investigators: Mark J. Zylka (contact PI), Juan Song

      $335,981
      award amount
    • 5R21NS142886-02Department: NIH department code
      Luminescence-based biosensor to non-invasively measure UBE3A activity in the brain
      $194,375
      award amount
    • 3UG3NS137515-01A1S1Department: NIH department code
      Genome editor therapy for Angelman syndrome
      $154,721
      award amount

  3. Mohanish P Deshmukh

    Leads 3 awards · $2,108,674

    • 5T32GM152316-03Department: NIH department code
      UNC Medical Scientist Training Program

      Principal investigators: Mohanish P Deshmukh (contact PI), Toni Darville

      $1,414,011
      award amount
    • 5R01AG082140-04Department: NIH department code
      miR-29: A brain homeostasis molecule for Alzheimer’s disease prevention
      $633,496
      award amount
    • 3T32GM152316-03S1Department: NIH department code
      UNC Medical Scientist Training Program

      Principal investigators: Mohanish P Deshmukh (contact PI), Toni Darville

      $61,167
      award amount

  4. Benjamin D Philpot

    Leads 4 awards · $1,984,448

    • 1R01EY037934-01Department: NIH department code
      Leveraging mouse models and retinal organoids to optimize a gene therapy for IMPG2-associated retinal degeneration

      Principal investigators: Benjamin D Philpot (contact PI), David M Gamm

      $603,053
      award amount
    • 5R01NS131615-04Department: NIH department code
      Small Molecule Therapeutic Discovery for Angelman Syndrome

      Principal investigators: Benjamin D Philpot (contact PI), Jeffrey Aube

      $562,899
      award amount
    • 5T32HD040127-25Department: NIH department code
      Postdoctoral Research in Neurodevelopmental Disorders

      Principal investigators: Benjamin D Philpot (contact PI), Mark D Shen

      $414,128
      award amount
    • 5R01NS129914-04Department: NIH department code
      Investigating UBE3A as a driver gene in Duplication 15q syndrome
      $404,368
      award amount

  5. Jessica E Thaxton

    Leads 3 awards · $1,859,332

    • 1R01CA305975-01A1Department: NIH department code
      Mechanisms of ATF4-Directed Macrophage Dysfunction in Cancer

      Principal investigators: Jessica E Thaxton (contact PI), Jennifer L. Guerriero

      $713,290
      award amount
    • 1R01CA310022-01Department: NIH department code
      Regulation of Immunometabolism by the Integrated Stress Response in Cancer
      $624,194
      award amount
    • 5R01CA288976-02Department: NIH department code
      Manipulating Lipid Metabolism to Reverse Immune Dysfunction in Solid Cancers
      $521,848
      award amount

  6. Michael C Bressan

    Leads 2 awards · $1,270,350

    • 5R01HL175577-02Department: NIH department code
      "Outside-in” Model of Cardiac Pacemaking: Extracellular Mediated Automaticity

      Principal investigators: Michael C Bressan (contact PI), Steven Poelzing

      $680,708
      award amount
    • 5R01HL146626-08Department: NIH department code
      Regulation of cardiac pacemaker cell cytoarchitecture
      $589,642
      award amount

  7. Scott Parnell

    Leads 2 awards · $1,157,022

    • 5R01AA026068-08Department: NIH department code
      Cellular Mechanisms in Fetal Alcohol Spectrum Disorders

      Principal investigators: Scott Parnell (contact PI), Kevin Peter Williams

      $625,123
      award amount
    • 5R01AA031346-04Department: NIH department code
      Characterizing the Genetics of FASD in Complementary Mouse and Fish Models

      Principal investigators: Scott Parnell (contact PI), Johann K Eberhart, Lisa M Tarantino

      $531,899
      award amount

  8. Adam Hantman

    Leads 2 awards · $1,007,970

    • 5R01NS145518-02Department: NIH department code
      Causally linking UBE3A misexpression to altered circuit dynamics controlling skilled movements

      Principal investigators: Adam Hantman (contact PI), Matthew Charles Judson

      $587,904
      award amount
    • 5R01NS118030-05Department: NIH department code
      Deconstructing the roles of basal ganglia and cerebellum-related thalamic inputs to motor cortex during control of dexterous behavior
      $420,066
      award amount

  9. Sarah Cohen

    Leads 2 awards · $993,038

    • 5R01AG081421-04Department: NIH department code
      Assessing the role of APOE in glial lipid droplet metabolism and function

      Principal investigators: Sarah Cohen (contact PI), Lance Allen Johnson

      $571,695
      award amount
    • 5R35GM133460-07Department: NIH department code
      Composition and Function of Membrane Contact Sites in Differentiation and Disease
      $421,343
      award amount

  10. Douglas H. Phanstiel

    Leads 2 awards · $930,804

    • 5R01AR079538-05Department: NIH department code
      Identifying novel osteoarthritis risk genes using GWAS, chondrocyte genomics, and genome editing

      Principal investigators: Douglas H. Phanstiel (contact PI), Richard F Loeser

      $474,204
      award amount
    • 5R35GM128645-08Department: NIH department code
      Mechanisms and impacts of chromatin looping
      $456,600
      award amount

  11. Katherine Therese Baldwin

    Leads 1 award · $915,362

    • 4DP2NS136873-02Department: NIH department code
      The facts of the matter: decoding the molecular properties of brain white matter using cell-type-specific quantitative proteomics
      $915,362
      award amount

  12. Eva S Anton

    Leads 1 award · $702,267

    • 5R35NS116859-07Department: NIH department code
      DEFINING MECHANISMS OF PROGENITOR BALANCE AND NEURONAL CONNECTIVITY
      $702,267
      award amount

  13. Lori L O'Brien

    Leads 1 award · $652,426

    • 5R01DK121014-07Department: NIH department code
      Trophic interactions directing proper kidney development
      $652,426
      award amount

  14. James E Bear

    Leads 1 award · $588,330

    • 5R35GM130312-08Department: NIH department code
      Systematic Analysis of the Actin Cytoskeleton and Directed Cell Migration
      $588,330
      award amount

  15. Stephanie Gupton

    Leads 2 awards · $512,175

    • 5R35GM135160-07Department: NIH department code
      Coordinated Cytoskeletal Dynamics and Membrane Remodeling in Cellular Shape Change
      $443,311
      award amount
    • 3R35GM135160-07S1Department: NIH department code
      Equipment supplement for R35
      $68,864
      award amount

  16. Natasha T Snider

    Leads 1 award · $479,397

    • 5R01NS136621-02Department: NIH department code
      Regenerative Strategies Targeting Retinoic Acid Signaling in Giant Axonal Neuropathy

      Principal investigators: Natasha T Snider (contact PI), Diane Armao

      $479,397
      award amount

    Also a principal investigator on 5T32GM133364-07, led by Kathleen M Caron.

  17. Patrick J Brennwald

    Leads 1 award · $457,596

    • 5R01GM054712-28Department: NIH department code
      Polarized Exocytosis: Rabs, Tethers, and SNAREs
      $457,596
      award amount

  18. Richard E Cheney

    Leads 1 award · $432,135

    • 1R35GM161616-01Department: NIH department code
      Molecular mechanisms of myosin-X and filopodial function
      $432,135
      award amount

  19. Graham Hugh Diering

    Leads 1 award · $427,625

    • 1R21MH144624-01Department: NIH department code
      Synaptic protein translation as an interface between circadian rhythms and the need for sleep
      $427,625
      award amount

  20. Adam David Gracz

    Leads 1 award · $422,179

    • 2R35GM142503-07Department: NIH department code
      Chromatin regulation of epithelial stem cell function
      $422,179
      award amount

  21. Robert Houston Dowen

    Leads 1 award · $422,076

    • 5R35GM137985-07Department: NIH department code
      Developmental and nutritional regulation of lipid metabolism
      $422,076
      award amount

  22. Jimena Giudice

    Leads 2 awards · $415,035

    • 5R35GM152426-03Department: NIH department code
      When alternative splicing meets cytoskeleton organization, local translation, and transcription regulation
      $383,755
      award amount
    • 3R35GM152426-03S1Department: NIH department code
      When alternative splicing meets cytoskeleton organization, local translation, and transcription regulation
      $31,280
      award amount

  23. Hokyung Kay Chung

    Leads 2 awards · $411,164

    • 1R21AI202462-01Department: NIH department code
      Designing AMR-resistant Organ via Rewiring of Aberrant Signaling to Effector Release (RASER)

      Principal investigators: Hokyung Kay Chung (contact PI), Jean Kwun

      $251,324
      award amount
    • 5K01EB034321-04Department: NIH department code
      Next-generation T cell therapy: SMARTER T cells for enhanced and durable anti-tumor immunity
      $159,840
      award amount

  24. Douglas M Cyr

    Leads 1 award · $410,708

    • 5R01GM151501-04Department: NIH department code
      Hsp40 and Hsp70 in Membrane Protein Triage
      $410,708
      award amount

  25. Toshihide Hige

    Leads 1 award · $324,185

    • 5R01DC018874-06Department: NIH department code
      Molecular and circuit mechanisms of learning supported by heterogeneous dopaminergic neurons
      $324,185
      award amount

  26. Heather A McCauley

    Leads 1 award · $113,089

    • 1R03DK142839-01A1Department: NIH department code
      Enteroendocrine regulation of intestinal barrier function
      $113,089
      award amount

  27. Yanna Tian

    Leads 1 award · $109,696

    • 1K99HL186015-01Department: NIH department code
      The role of apelin receptor signaling in lymphatic vessel
      $109,696
      award amount

  28. Sarah Ray McLarnon

    Leads 1 award · $91,380

    • 1K99DK146140-01A1Department: NIH department code
      Investigating the implications of vascular patterning and maturation for kidney injury and repair
      $91,380
      award amount

  29. Jessica Leigh Cote

    Leads 1 award · $81,580

    • 5F32AR084326-03Department: NIH department code
      Clathrin alternative splicing in skeletal muscle development
      $81,580
      award amount

  30. Udodirim Onwubiko

    Leads 1 award · $79,348

    • 5F32HD117621-02Department: NIH department code
      Defining the contributions of apoptosis to germline syncytium function during oogenesis
      $79,348
      award amount

  31. Nicholas W Ringelberg

    Leads 1 award · $50,220

    • 5F30HD111296-03Department: NIH department code
      Neural Circuit Mechanisms of Seizure Susceptibility in a Mouse Model of Angelman Syndrome
      $50,220
      award amount

  32. Samantha Ella Ryken

    Leads 1 award · $50,114

    • 5F31NS141456-02Department: NIH department code
      Defining the regulation of exocytosis in developing neurons
      $50,114
      award amount

  33. Emily Claire Bulik-Sullivan

    Leads 1 award · $48,348

    • 5F30HL172628-03Department: NIH department code
      Therapeutic potential of CC-90009 for cystic fibrosis
      $48,348
      award amount

  34. Hayli Elizabeth Spence-Osorio

    Leads 1 award · $44,404

    • 1F31NS145447-01A1Department: NIH department code
      Regulation of astrocyte maturation and synapse development by PTPRZ1
      $44,404
      award amount

  35. Anna Beeson

    Leads 1 award · $44,340

    • 1F31HD122384-01Department: NIH department code
      Pinopode formation in endometrial receptivity and fertility
      $44,340
      award amount

  36. Gabrielle Bais

    Leads 1 award · $42,767

    • 5F31HL176049-02Department: NIH department code
      The roles of Fragile-X related protein 1 in cardiomyocyte and heart biology
      $42,767
      award amount

  37. Juliet Stanton King

    Leads 1 award · $42,731

    • 5F31DE033915-02Department: NIH department code
      Determining the role of cell-cell adhesions in palate closure
      $42,731
      award amount

  38. Kayla Kristine Mason

    Leads 1 award · $41,816

    • 1F31HL184778-01Department: NIH department code
      Sex-Specific Regulation of Cardiac Excitation-Contraction Coupling by the RNA Helicase DDX3X
      $41,816
      award amount

  39. Katherine Descant

    Leads 1 award · $41,404

    • 1F31EY039091-01Department: NIH department code
      Developing a gene therapy for IMPG2-Associated Retinal Degeneration in a knockout mouse model
      $41,404
      award amount

  40. Madison Amy Kalk

    Leads 1 award · $41,340

    • 1F31HL186613-01Department: NIH department code
      Cellular Context of RAMP-GPCR Signaling in Lymphatic Microvasculature
      $41,340
      award amount

  41. Joseph Krzeski

    Leads 1 award · $41,204

    • 5F31NS139445-03Department: NIH department code
      The Role of UBE3A Isoforms in AS-associated Seizure Susceptibility
      $41,204
      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.