Pharmacology at University of North Carolina at Chapel Hill

Leads a grant in this department

58 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Roth, Bryan L.

   Leads 5 awards · $4,839,679

   • 5U24DK116195-06Department: NIH department code

     Illuminating the Druggable GPCR-ome
     $2,239,055

     award amount
   • 3U24DK116195-05S1Department: NIH department code

     Illuminating the Druggable GPCR-ome
     $749,510

     award amount
   • 5R37DA045657-05Department: NIH department code

     Mechanistic insights into LSD actions at 5-HT2A serotonin receptors
     $639,458

     award amount
   • 2R01MH112205-06Department: NIH department code

     Molecular Details of Psychoactive Drug Actions
     $629,016

     award amount
   • 1R01DA055656-01Department: NIH department code

     STRUCTURE AND FUNCTION OF MRG-FAMILY RECEPTORS
     $582,640

     award amount

2. Johnson, Gary L.

   Leads 1 award · $2,252,146

   • 5U24DK116204-06Department: NIH department code

     Illuminating Function of the Understudied Druggable Kinome
     $2,252,146

     award amount

3. Kash, Thomas L.

   Leads 2 awards · $2,154,339

   • 5P60AA011605-25Department: NIH department code

     Molecular and Circuit Pathogenesis of Alcohol Addiction
     $1,737,035

     award amount
   • 5R01NS122230-02Department: NIH department code

     Determining the impact of BNST CRF systems on inflammatory pain-induced disruptions of behavior
     $417,304

     award amount

4. Crews, Fulton T

   Leads 3 awards · $1,368,771

   • 5U01AA020023-13Department: NIH department code

     5/8 NADIA U01 Effects of Adolescent Alcohol on adult brain Neurocircuitry
     $570,876

     award amount
   • 5U24AA020024-13Department: NIH department code

     1/1 NADIA U24 Administrative Core
     $486,895

     award amount
   • 1U54AA030463-01Department: NIH department code

     2/2 Partnerships to Enhance Alcohol Research Across NCCU and UNC (PEAR-NC)
     $311,000

     award amount

5. Emanuele, Michael James

   Leads 5 awards · $1,331,507

   • 5T32GM135095-03Department: NIH department code

     Predoctoral Training in the Pharmacological Sciences
     $520,362

     award amount
   • 5R01GM134231-03Department: NIH department code

     Deubiquitinases in Cell Cycle Control
     $352,617

     award amount
   • 2R01GM120309-06Department: NIH department code

     SCF Ubiquitin Ligases in Cell Cycle Control and Chromosome Stability
     $314,382

     award amount
   • 3R01GM134231-03S1Department: NIH department code

     Deubiquitinases in Cell Cycle Control
     $78,554

     award amount
   • 3R01GM134231-03S2Department: NIH department code

     Deubiquitinases in Cell Cycle Control
     $65,592

     award amount

6. Lai, Samuel

   Leads 2 awards · $1,208,378

   • 1R01AI165853-01A1Department: NIH department code

     Engineered “muco-trapping” antibodies for inhaled therapy of parainfluenza and human metapneumovirus infections
     $688,413

     award amount
   • 5R01HD101562-03Department: NIH department code

     Engineering bispecific antibodies for non-hormonal contraception
     $519,965

     award amount

7. James, Lindsey Ingerman

   Leads 2 awards · $1,205,956

   • 4R33DA047023-04Department: NIH department code

     POLYCOMB REPRESSIVE COMLEXE AS KEY REGULATORS OF HIV LATENCY AND TARGETS FOR LATENCY REVERSAL
     $878,498

     award amount
   • 5R01CA242305-04Department: NIH department code

     DISCOVERY OF FIRST-IN-CLASS NSD2 DEGRADERS FOR CANCER THERAPY
     $327,458

     award amount

8. Baldwin, Albert Sidney

   Leads 1 award · $1,150,319

   • 5U01TR003715-02Department: NIH department code

     A consortium effort to translate therapies for neurological diseases via an ex vivo organotypic platform
     $1,150,319

     award amount

9. Lawrence, David S.

   Leads 2 awards · $1,061,003

   • 5R01HL153744-02Department: NIH department code

     Design and Application of Photoresponsive Modules in Circulating Erythrocytes
     $720,847

     award amount
   • 5R01NS103486-05Department: NIH department code

     Spatiotemporal Control of Migratory Cellular Behavior
     $340,156

     award amount

10. Aube, Jeffrey

    Leads 2 awards · $1,043,892

    • 5R01AI155510-02Department: NIH department code

      Discovery of Phospopantetheinyl Transferse Inhibitors Against Mycobacterium tuberculosis
      $779,927

      award amount
    • 5T32GM135122-02Department: NIH department code

      UNC Chemical Biology Interface Training Program
      $263,965

      award amount

11. Song, Juan

    Leads 2 awards · $1,032,420

    • 5R01MH122692-03Department: NIH department code

      Sex-dependent role of 5HT1A receptors in adult neurogenesis and hippocampal function
      $571,019

      award amount
    • 5R01NS121300-02Department: NIH department code

      Role of Cholecystokinin in the Dentate Gyrus
      $461,401

      award amount

12. Ainslie, Kristy M

    Leads 2 awards · $945,210

    • 5R01AI147497-03Department: NIH department code

      Optimizing a Universal Influenza Subunit Nano/Microparticulate Vaccine
      $568,652

      award amount
    • 5R01AI137525-05Department: NIH department code

      Biomaterials to study tolerance immune induction kinetics
      $376,558

      award amount

13. Dumond, Julie Brumer

    Leads 2 awards · $939,703

    • 5R01AI153007-02Department: NIH department code

      Quantifying Sex-and-Age-Related Differences in Antiretroviral Exposure and Adverse Effects in the MACS/WIHS Combined Cohort Study
      $724,842

      award amount
    • 5R01HD096435-05Department: NIH department code

      Physiologically-Based Pharmacokinetic Modeling to Guide Drug Dosing in Children with Obesity
      $214,861

      award amount

14. Der, Channing J.

    Leads 1 award · $899,999

    • 5R35CA232113-05Department: NIH department code

      Targeting undruggable RAS for cancer treatment
      $899,999

      award amount

15. Ritola, Kimberly

    Leads 2 awards · $859,599

    • 5R01FD007476-02Department: NIH department code

      Nanopore Methods for Determining Capsid Viability
      $461,132

      award amount
    • 5U24NS124025-02Department: NIH department code

      BRAIN Viral Vector Services and Distribution Core
      $398,467

      award amount

16. Nguyen, Juliane

    Leads 2 awards · $824,884

    • 1R01HL161456-01A1Department: NIH department code

      Engineering a cross-linked cellular network for cardiac repair
      $479,969

      award amount
    • 5R01CA241679-03Department: NIH department code

      Polarizing Macrophages to Tumor Suppressors by Blocking Multiple CCR2 Chemokine Receptor Epitopes
      $344,915

      award amount

17. Bizon, Christopher

    Leads 1 award · $819,030

    • 1U24ES035214-01Department: NIH department code

      Supporting Biomedical Discovery with the ROBOKOP Graph Knowledgebase.
      $819,030

      award amount

18. Graham, Douglas K

    Leads 2 awards · $813,679

    • 5R01CA249190-03Department: NIH department code

      MERTK/AXL dual inhibitors provide novel treatment for cancer by targeting tumor cells and activating anti-tumor immunity
      $497,060

      award amount
    • 5R01CA259077-02Department: NIH department code

      Novel TYRO3 inhibitors for treatment of cancer
      $316,619

      award amount

19. Hahn, Klaus M.

    Leads 1 award · $810,270

    • 2R35GM122596-06Department: NIH department code

      Dissecting signaling in vivo via precise control and visualization of protein activity
      $810,270

      award amount

20. Kabanov, Alexander V

    Leads 3 awards · $768,844

    • 5R01CA264488-02Department: NIH department code

      TOWARD TRANSLATION OF NANFORMULATED PACLITAXEL-PLATINUM COMBINATION
      $600,798

      award amount
    • 3R01CA264488-02S1Department: NIH department code

      TOWARD TRANSLATION OF NANFORMULATED PACLITAXEL-PLATINUM COMBINATION
      $117,913

      award amount
    • 3R01CA264488-01S1Department: NIH department code

      Diversity Supplement - TOWARD TRANSLATION OF NANFORMULATED PACLITAXEL-PLATINUM COMBINATION
      $50,133

      award amount

21. Crino, Peter B

    Leads 2 awards · $756,927

    • 5R01NS115017-03Department: NIH department code

      Defining disease mechanisms in SLC35A2 epilepsy
      $688,977

      award amount
    • 3R01NS115017-03S1Department: NIH department code

      Defining disease mechanisms in SLC35A2 epilepsy
      $67,950

      award amount

22. Calabrese, Joseph Mauro

    Leads 2 awards · $721,125

    • 5R01GM136819-03Department: NIH department code

      Cooperative control of Polycomb Repressive Complexes by long noncoding RNAs, CpG island DNA, and RNA-binding proteins
      $386,771

      award amount
    • 2R01GM121806-06Department: NIH department code

      Mechanisms of gene silencing induced by long noncoding RNAs
      $334,354

      award amount

23. Brouwer, Kim L.r.

    Leads 1 award · $710,612

    • 5T32GM086330-12Department: NIH department code

      UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program
      $710,612

      award amount

24. Liu, Rihe

    Leads 2 awards · $668,029

    • 1R01EB032865-01Department: NIH department code

      A Wholly Protein-based Self-assembly Nanoplatform for TNBC-specific Combination Therapy
      $473,654

      award amount
    • 5R21AI163793-02Department: NIH department code

      Trimerization of the N-terminal Domain of ACE2 for Bifunctional Trapping of Future SARS-CoV-2 Variants
      $194,375

      award amount

25. Dohlman, Henrik G.

    Leads 1 award · $659,119

    • 5R35GM118105-07Department: NIH department code

      Negative and positive feedback in cell signaling
      $659,119

      award amount

26. Batrakova, Elena

    Leads 2 awards · $636,147

    • 5R01NS102412-05Department: NIH department code

      Cell-based Platform for Gene Delivery to the Brain
      $338,579

      award amount
    • 5R01NS112019-04Department: NIH department code

      Extracellular Vesicles for CNS Delivery of Therapeutic Enzymes to Treat Lysosomal Storage Disorders
      $297,568

      award amount

27. Coleman, Leon Garland

    Leads 2 awards · $573,406

    • 5R01AA028924-03Department: NIH department code

      Microglia Activation and TLR-induced Neurodegeneration by Alcohol Promotes Progression of Alzheimer Pathology
      $388,750

      award amount
    • 5R21AA028599-02Department: NIH department code

      Ethanol Inhibition of anti-PD-1 Immunotherapy via T-cell Dysfunction and Intestinal Dysbiosis
      $184,656

      award amount

28. Lee, Andrew L

    Leads 3 awards · $554,263

    • 1R35GM144348-01Department: NIH department code

      Mechanisms and dynamics of allosteric function in proteins
      $462,164

      award amount
    • 3R35GM144348-01S2Department: NIH department code

      Mechanisms and dynamics of allosteric function in proteins
      $77,043

      award amount
    • 3R35GM144348-01S1Department: NIH department code

      Equipment Supplement to Mechanisms and dynamics of allosteric function in proteins
      $15,056

      award amount

29. Chang, Sha X

    Leads 1 award · $544,735

    • 5R01CA247652-02Department: NIH department code

      Minibeam Radiation Therapy Enhanced Delivery of Nanoparticle Anticancer Agents to Pancreatic Cancer Tumors
      $544,735

      award amount

30. Gonzalez, Daniel

    Leads 1 award · $491,626

    • 5R01HD102949-02Department: NIH department code

      Application of Physiologically-Based Pharmacokinetic Modeling to Characterize Drug-Drug Interactions in Infants
      $491,626

      award amount

31. Hingtgen, Shawn

    Leads 1 award · $467,151

    • 1R01CA269974-01Department: NIH department code

      Harnessing Continuous Liquid Interface 3D Printing to Improve Tumor-homing Stem Cell Therapy for Post-surgical Brain Cancer
      $467,151

      award amount

32. Dominguez, Daniel Issac

    Leads 2 awards · $464,644

    • 5R35GM142864-02Department: NIH department code

      Protein Disorder as a Mechanism of RNA Binding and Regulation
      $388,750

      award amount
    • 3R35GM142864-02S1Department: NIH department code

      Protein Disorder as a Mechanism of RNA Binding and Regulation
      $75,894

      award amount

33. Schisler, Jonathan C.

    Leads 1 award · $456,458

    • 5R01AG066710-03Department: NIH department code

      Protein quality control in age-related diseases
      $456,458

      award amount

34. Davis, Ian J

    Leads 2 awards · $453,808

    • 5R01GM138912-02Department: NIH department code

      Development of a cavitation enhancement technology to access archived tissues for epigenetic-based biomedical research
      $400,961

      award amount
    • 3R01GM138912-02S1Department: NIH department code

      Development of a cavitation enhancement technology to access archived tissues for epigenetic-based biomedical research
      $52,847

      award amount

35. Elston, Timothy C

    Leads 1 award · $450,950

    • 5R35GM127145-05Department: NIH department code

      Mathematical modeling of cellular signaling systems
      $450,950

      award amount

36. Crews, Fulton T

    Leads 1 award · $441,187

    • 5T32AA007573-25Department: NIH department code

      Molecular and Cellular Alcohol Research Training
      $441,187

      award amount

37. Frankowski, Kevin J.

    Leads 2 awards · $427,625

    • 5R21AG068833-02Department: NIH department code

      D1 dopamine receptor positive allosteric modulators as a practical treatment for cognitive decline
      $233,250

      award amount
    • 5UG3DA050820-02Department: NIH department code

      Negative allosteric modulators of the D3 dopamine receptor as therapeutic leads for substance use disorders
      $194,375

      award amount

38. Frye, Stephen Vernon

    Leads 1 award · $425,839

    • 5R35GM139514-02Department: NIH department code

      PROBING ALLOSTERY IN METHYL-LYSINE READER DOMAINS
      $425,839

      award amount

39. Roberts, Megan C.

    Leads 1 award · $420,769

    • 1R21HG012672-01Department: NIH department code

      Implementing and Evaluating Genetic Screening in Healthy Adults for Precision Public Health
      $420,769

      award amount

40. Bowers, Albert A

    Leads 1 award · $401,511

    • 2R35GM125005-06Department: NIH department code

      Chemoenzymatic Synthesis, Mode of Action and Evolution of Natural Product-based Macrocycles
      $401,511

      award amount

41. Aleman, Maria M.

    Leads 1 award · $394,214

    • 5R01DK124773-03Department: NIH department code

      Iron-sensitive RNA regulation during erythropoiesis
      $394,214

      award amount

42. Lee, Craig R

    Leads 1 award · $393,579

    • 5R01HD098742-03Department: NIH department code

      Mechanisms of Altered Hepatic Drug Metabolism and Transport in Pregnancy
      $393,579

      award amount

43. Brown, Nicholas Gene

    Leads 1 award · $388,750

    • 5R35GM128855-05Department: NIH department code

      Spindle Assembly Checkpoint Silencing
      $388,750

      award amount

44. Li, Chengwen

    Leads 1 award · $388,750

    • 5R01HL151348-02Department: NIH department code

      Development of AAV vectors for CF therapy
      $388,750

      award amount

45. Sokolsky-Papkov, Marina

    Leads 1 award · $388,750

    • 1R01NS125073-01Department: NIH department code

      Nanoformulated small molecule immunotherapy for SHH medulloblastoma
      $388,750

      award amount

46. McGinty, Robert

    Leads 1 award · $382,895

    • 5R35GM133498-04Department: NIH department code

      Molecular Mechanisms of Chromatin Recognition
      $382,895

      award amount

47. Herman, Melissa A

    Leads 1 award · $349,875

    • 5R01AA026858-04Department: NIH department code

      The role of a nucleus tractus solitarius-central amygdala circuit in alcohol-induced plasticity and drinking behavior
      $349,875

      award amount

48. Bryant, Kirsten L

    Leads 1 award · $315,401

    • 5R37CA251877-03Department: NIH department code

      Mechanistic dissection and inhibitor targeting of autophagy in RAS driven cancers
      $315,401

      award amount

49. Graves, Lee M

    Leads 1 award · $314,448

    • 5R01GM138520-03Department: NIH department code

      Elucidating the mechanism of action of novel ClpP activators in activation of the mitochondrial unfolded protein response.
      $314,448

      award amount

50. Hathaway, Nathaniel A.

    Leads 1 award · $304,179

    • 5R01GM132299-03Department: NIH department code

      Computational and experimental insights into the structure and dynamics of heterochromatin
      $304,179

      award amount

51. Asrican, Brent

    Leads 1 award · $194,375

    • 5R21AG074293-02Department: NIH department code

      Altered Diversity of Astrocyte sub-types and Signaling Capabilities in Alzheimer's Disease
      $194,375

      award amount

52. Cottrell, MacKenzie

    Leads 1 award · $192,295

    • 5R21AI157853-02Department: NIH department code

      Accelerating to the Cure: A Novel IVIVE Model for Advancing HIV Eradication Strategies
      $192,295

      award amount

53. Mercer-Smith, Alison R.

    Leads 1 award · $48,776

    • 5F30CA243270-04Department: NIH department code

      Therapeutic Engineered Stem Cells as a New Adjuvant Therapy for Non-Small Cell Lung Cancer Brain Metastases
      $48,776

      award amount

54. Truong, Andrew

    Leads 1 award · $46,752

    • 5F31CA247250-03Department: NIH department code

      Effect of APOBEC3 on Bladder Cancer Biology and Response to Immunotherapy
      $46,752

      award amount

55. Zhu, Manhua

    Leads 1 award · $39,967

    • 5F31DA053064-02Department: NIH department code

      Impact of electronic nicotine vapor on mouse mesolimbic CRFR1 circuitry and motivated behavior
      $39,967

      award amount

56. Cherney, Rachel Elizabeth

    Leads 1 award · $38,562

    • 5F31HD103334-03Department: NIH department code

      Regulation of Polycomb by long noncoding RNAs during pre-implantation development
      $38,562

      award amount

57. Cartaya, Ana

    Leads 1 award · $36,171

    • 5F31HL156427-02Department: NIH department code

      Selective delivery of superoxide dismutase and catalase for restenosis prevention
      $36,171

      award amount

58. Zarmer, Sandra

    Leads 1 award · $35,170

    • 5F31CA257224-02Department: NIH department code

      Identifying targets for combination therapy with FOLFIRINOX and investigating cell polarity loss as a potential driver of invasion in basal-like PDAC
      $35,170

      award amount