Pharmacology at University of North Carolina at Chapel Hill

Leads a grant in this department

63 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Song, Juan

   Leads 4 awards · $2,515,914

   • 1R01MH132222-01A1Department: NIH department code

     Regulation and functional contribution of hypothalamic modified adult hippocampal neurogenesis
     $757,874

     award amount
   • 1R01AG084207-01Department: NIH department code

     Enhancing adult-born neurons to restore brain functions in Alzheimer's disease
     $725,620

     award amount
   • 5R01MH122692-04Department: NIH department code

     Sex-dependent role of 5HT1A receptors in adult neurogenesis and hippocampal function
     $571,019

     award amount
   • 5R01NS121300-03Department: NIH department code

     Role of Cholecystokinin in the Dentate Gyrus
     $461,401

     award amount

2. Kash, Thomas L.

   Leads 2 awards · $2,144,749

   • 2P60AA011605-26Department: NIH department code

     Molecular and Circuit Pathogenesis of Alcohol Use Disorders
     $1,749,377

     award amount
   • 5R01NS122230-03Department: NIH department code

     Determining the impact of BNST CRF systems on inflammatory pain-induced disruptions of behavior
     $395,372

     award amount

3. Roth, Bryan L.

   Leads 3 awards · $1,842,636

   • 4R37DA045657-06Department: NIH department code

     Mechanistic insights into LSD actions at 5-HT2A serotonin receptors
     $664,506

     award amount
   • 5R01MH112205-07Department: NIH department code

     Molecular Details of Psychoactive Drug Actions
     $611,184

     award amount
   • 5R01DA055656-02Department: NIH department code

     STRUCTURE AND FUNCTION OF MRG-FAMILY RECEPTORS
     $566,946

     award amount

4. Lai, Samuel

   Leads 3 awards · $1,397,104

   • 5R01AI165853-02Department: NIH department code

     Engineered “muco-trapping” antibodies for inhaled therapy of parainfluenza and human metapneumovirus infections
     $688,330

     award amount
   • 5R01HD101562-04Department: NIH department code

     Engineering bispecific antibodies for non-hormonal contraception
     $493,843

     award amount
   • 1R21CA273983-01A1Department: NIH department code

     Engineering Siglec15/TGF-beta targeted bispecific antibodies that modulate the tumor microenvironment and enhances T-cell immunotherapy against pancreatic cancer
     $214,931

     award amount

5. Crews, Fulton T

   Leads 3 awards · $1,368,771

   • 5U01AA020023-14Department: NIH department code

     5/8 NADIA U01 Effects of Adolescent Alcohol on adult brain Neurocircuitry
     $570,876

     award amount
   • 5U24AA020024-14Department: NIH department code

     1/1 NADIA U24 Administrative Core
     $486,895

     award amount
   • 5U54AA030463-02Department: NIH department code

     2/2 Partnerships to Enhance Alcohol Research Across NCCU and UNC (PEAR-NC)
     $311,000

     award amount

6. James, Lindsey Ingerman

   Leads 2 awards · $1,205,782

   • 5R33DA047023-05Department: NIH department code

     POLYCOMB REPRESSIVE COMLEXE AS KEY REGULATORS OF HIV LATENCY AND TARGETS FOR LATENCY REVERSAL
     $878,498

     award amount
   • 5R01CA242305-05Department: NIH department code

     DISCOVERY OF FIRST-IN-CLASS NSD2 DEGRADERS FOR CANCER THERAPY
     $327,284

     award amount

7. Baldwin, Albert Sidney

   Leads 1 award · $1,135,383

   • 5U01TR003715-03Department: NIH department code

     A consortium effort to translate therapies for neurological diseases via an ex vivo organotypic platform
     $1,135,383

     award amount

8. Aube, Jeffrey

   Leads 2 awards · $1,048,441

   • 5R01AI155510-03Department: NIH department code

     Discovery of Phospopantetheinyl Transferse Inhibitors Against Mycobacterium tuberculosis
     $778,372

     award amount
   • 5T32GM135122-03Department: NIH department code

     UNC Chemical Biology Interface Training Program
     $270,069

     award amount

9. Kabanov, Alexander V

   Leads 2 awards · $923,962

   • 5R01CA264488-03Department: NIH department code

     TOWARD TRANSLATION OF NANFORMULATED PACLITAXEL-PLATINUM COMBINATION
     $496,337

     award amount
   • 1R21NS135362-01Department: NIH department code

     Naturally Targeted Exosomal TLR7/8 Agonist for Immunotherapy of Medulloblastoma
     $427,625

     award amount

10. Der, Channing J.

    Leads 1 award · $902,485

    • 5R35CA232113-06Department: NIH department code

      Targeting undruggable RAS for cancer treatment
      $902,485

      award amount

11. Nguyen, Juliane

    Leads 3 awards · $897,656

    • 5R01HL161456-02Department: NIH department code

      Engineering a cross-linked cellular network for cardiac repair
      $480,498

      award amount
    • 5R01CA241679-04Department: NIH department code

      Polarizing Macrophages to Tumor Suppressors by Blocking Multiple CCR2 Chemokine Receptor Epitopes
      $344,915

      award amount
    • 3R01CA241679-04S1Department: NIH department code

      Polarizing Macrophages to Tumor Suppressors by Blocking Multiple CCR2 Chemokine Receptor Epitopes
      $72,243

      award amount

12. Graham, Douglas K

    Leads 2 awards · $813,679

    • 5R01CA249190-04Department: NIH department code

      MERTK/AXL dual inhibitors provide novel treatment for cancer by targeting tumor cells and activating anti-tumor immunity
      $497,060

      award amount
    • 5R01CA259077-03Department: NIH department code

      Novel TYRO3 inhibitors for treatment of cancer
      $316,619

      award amount

13. Hahn, Klaus M.

    Leads 1 award · $810,270

    • 5R35GM122596-07Department: NIH department code

      Dissecting signaling in vivo via precise control and visualization of protein activity
      $810,270

      award amount

14. Ritola, Kimberly

    Leads 2 awards · $795,958

    • 5R01FD007476-03Department: NIH department code

      Nanopore Methods for Determining Capsid Viability
      $398,075

      award amount
    • 5U24NS124025-03Department: NIH department code

      BRAIN Viral Vector Services and Distribution Core
      $397,883

      award amount

15. Bizon, Christopher

    Leads 1 award · $787,968

    • 5U24ES035214-02Department: NIH department code

      Supporting Biomedical Discovery with the ROBOKOP Graph Knowledgebase.
      $787,968

      award amount

16. Emanuele, Michael James

    Leads 4 awards · $745,876

    • 5R01GM134231-04Department: NIH department code

      Deubiquitinases in Cell Cycle Control
      $352,617

      award amount
    • 5R01GM120309-07Department: NIH department code

      SCF Ubiquitin Ligases in Cell Cycle Control and Chromosome Stability
      $314,382

      award amount
    • 3R01GM120309-07S1Department: NIH department code

      SCF Ubiquitin Ligases in Cell Cycle Control and Chromosome Stability
      $39,600

      award amount
    • 3R01GM134231-04S1Department: NIH department code

      Deubiquitinases in Cell Cycle Control
      $39,277

      award amount

17. Brouwer, Kim L.r.

    Leads 1 award · $744,336

    • 5T32GM086330-13Department: NIH department code

      UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program
      $744,336

      award amount

18. Dumond, Julie Brumer

    Leads 1 award · $744,135

    • 5R01AI153007-03Department: NIH department code

      Quantifying Sex-and-Age-Related Differences in Antiretroviral Exposure and Adverse Effects in the MACS/WIHS Combined Cohort Study
      $744,135

      award amount

19. Dohlman, Henrik G.

    Leads 2 awards · $729,769

    • 5R35GM118105-08Department: NIH department code

      Negative and positive feedback in cell signaling
      $659,119

      award amount
    • 3R35GM118105-08S1Department: NIH department code

      Negative and positive feedback in cell signaling
      $70,650

      award amount

20. Calabrese, Joseph Mauro

    Leads 2 awards · $721,125

    • 5R01GM136819-04Department: NIH department code

      Cooperative control of Polycomb Repressive Complexes by long noncoding RNAs, CpG island DNA, and RNA-binding proteins
      $386,771

      award amount
    • 5R01GM121806-07Department: NIH department code

      Mechanisms of gene silencing induced by long noncoding RNAs
      $334,354

      award amount

21. Lawrence, David S.

    Leads 1 award · $720,847

    • 5R01HL153744-03Department: NIH department code

      Design and Application of Photoresponsive Modules in Circulating Erythrocytes
      $720,847

      award amount

22. Crino, Peter B

    Leads 1 award · $688,977

    • 5R01NS115017-04Department: NIH department code

      Defining disease mechanisms in SLC35A2 epilepsy
      $688,977

      award amount

23. Fallon, John Kevin

    Leads 1 award · $600,000

    • 1S10OD032350-01A1Department: NIH department code

      Shared LC-MS/MS for Quantitative Targeted Proteomics
      $600,000

      award amount

24. Ainslie, Kristy M

    Leads 1 award · $560,411

    • 5R01AI147497-04Department: NIH department code

      Optimizing a Universal Influenza Subunit Nano/Microparticulate Vaccine
      $560,411

      award amount

25. Crews, Fulton T

    Leads 1 award · $554,616

    • 2T32AA007573-26Department: NIH department code

      Molecular and Cellular Alcohol Research Training
      $554,616

      award amount

26. Schisler, Jonathan C.

    Leads 3 awards · $553,397

    • 5R01AG066710-04Department: NIH department code

      Protein quality control in age-related diseases
      $453,908

      award amount
    • 3R01AG066710-04S1Department: NIH department code

      Protein quality control in age-related diseases
      $70,227

      award amount
    • 3R01AG066710-03S1Department: NIH department code

      Organotypic Slice Culture Model of CHIP Mediated Neuroprotection
      $29,262

      award amount

27. Chang, Sha X

    Leads 1 award · $544,735

    • 5R01CA247652-03Department: NIH department code

      Minibeam Radiation Therapy Enhanced Delivery of Nanoparticle Anticancer Agents to Pancreatic Cancer Tumors
      $544,735

      award amount

28. Calabrese, Joseph Mauro

    Leads 1 award · $530,535

    • 5T32GM135095-04Department: NIH department code

      Predoctoral Training in the Pharmacological Sciences
      $530,535

      award amount

29. Liu, Rihe

    Leads 1 award · $473,654

    • 5R01EB032865-02Department: NIH department code

      A Wholly Protein-based Self-assembly Nanoplatform for TNBC-specific Combination Therapy
      $473,654

      award amount

30. Elston, Timothy C

    Leads 1 award · $467,252

    • 2R35GM127145-06Department: NIH department code

      Mathematical modeling of cellular signaling systems
      $467,252

      award amount

31. Lee, Andrew L

    Leads 1 award · $462,164

    • 5R35GM144348-02Department: NIH department code

      Mechanisms and dynamics of allosteric function in proteins
      $462,164

      award amount

32. Brown, Nicholas Gene

    Leads 1 award · $454,118

    • 2R35GM128855-06Department: NIH department code

      Spindle Assembly Checkpoint Silencing
      $454,118

      award amount

33. Sondek, John E

    Leads 1 award · $427,684

    • 1R35GM149299-01Department: NIH department code

      Phospholipase C Isozymes
      $427,684

      award amount

34. Hingtgen, Shawn

    Leads 1 award · $427,463

    • 5R01CA269974-02Department: NIH department code

      Harnessing Continuous Liquid Interface 3D Printing to Improve Tumor-homing Stem Cell Therapy for Post-surgical Brain Cancer
      $427,463

      award amount

35. Frye, Stephen Vernon

    Leads 1 award · $425,839

    • 5R35GM139514-03Department: NIH department code

      PROBING ALLOSTERY IN METHYL-LYSINE READER DOMAINS
      $425,839

      award amount

36. Bowers, Albert A

    Leads 2 awards · $414,837

    • 5R35GM125005-07Department: NIH department code

      Chemoenzymatic Synthesis, Mode of Action and Evolution of Natural Product-based Macrocycles
      $389,341

      award amount
    • 3R35GM125005-06S1Department: NIH department code

      Chemoenzymatic Synthesis, Mode of Action and Evolution of Natural Product-based Macrocycles
      $25,496

      award amount

37. Davis, Ian J

    Leads 1 award · $400,726

    • 5R01GM138912-03Department: NIH department code

      Development of a cavitation enhancement technology to access archived tissues for epigenetic-based biomedical research
      $400,726

      award amount

38. Aleman, Maria M.

    Leads 1 award · $394,214

    • 5R01DK124773-04Department: NIH department code

      Iron-sensitive RNA regulation during erythropoiesis
      $394,214

      award amount

39. Coleman, Leon Garland

    Leads 1 award · $388,750

    • 5R01AA028924-04Department: NIH department code

      Microglia Activation and TLR-induced Neurodegeneration by Alcohol Promotes Progression of Alzheimer Pathology
      $388,750

      award amount

40. Dominguez, Daniel Issac

    Leads 1 award · $388,750

    • 5R35GM142864-03Department: NIH department code

      Protein Disorder as a Mechanism of RNA Binding and Regulation
      $388,750

      award amount

41. Li, Chengwen

    Leads 1 award · $388,750

    • 5R01HL151348-03Department: NIH department code

      Development of AAV vectors for CF therapy
      $388,750

      award amount

42. Sokolsky-Papkov, Marina

    Leads 1 award · $388,750

    • 5R01NS125073-02Department: NIH department code

      Nanoformulated small molecule immunotherapy for SHH medulloblastoma
      $388,750

      award amount

43. McGinty, Robert

    Leads 1 award · $382,895

    • 5R35GM133498-05Department: NIH department code

      Molecular Mechanisms of Chromatin Recognition
      $382,895

      award amount

44. Lee, Craig R

    Leads 1 award · $381,351

    • 5R01HD098742-04Department: NIH department code

      Mechanisms of Altered Hepatic Drug Metabolism and Transport in Pregnancy
      $381,351

      award amount

45. Bryant, Kirsten L

    Leads 1 award · $352,097

    • 5R37CA251877-04Department: NIH department code

      Mechanistic dissection and inhibitor targeting of autophagy in RAS driven cancers
      $352,097

      award amount

46. Herman, Melissa A

    Leads 1 award · $349,875

    • 5R01AA026858-05Department: NIH department code

      The role of a nucleus tractus solitarius-central amygdala circuit in alcohol-induced plasticity and drinking behavior
      $349,875

      award amount

47. Cox, Adrienne D

    Leads 1 award · $314,720

    • 2T32CA071341-26Department: NIH department code

      Cancer Cell Biology Training Program
      $314,720

      award amount

48. Graves, Lee M

    Leads 1 award · $314,448

    • 5R01GM138520-04Department: NIH department code

      Elucidating the mechanism of action of novel ClpP activators in activation of the mitochondrial unfolded protein response.
      $314,448

      award amount

49. Batrakova, Elena

    Leads 1 award · $297,568

    • 5R01NS112019-05Department: NIH department code

      Extracellular Vesicles for CNS Delivery of Therapeutic Enzymes to Treat Lysosomal Storage Disorders
      $297,568

      award amount

50. Miao, Yinglong

    Leads 1 award · $295,313

    • 7R01GM132572-06Department: NIH department code

      Enhanced Sampling of G-Protein-Coupled Receptor-G Protein Interactions
      $295,313

      award amount

51. Brudno, Yevgeny

    Leads 1 award · $261,931

    • 7R33CA281875-02Department: NIH department code

      MASTER Scaffolds for Rapid, Single-Step Manufacture and Prototyping of CAR-T cells
      $261,931

      award amount

52. Macht, Victoria Alice

    Leads 1 award · $125,519

    • 5K99AA030089-02Department: NIH department code

      Adolescent intermittent ethanol induction of neuroimmune signaling disrupts the mature phenotype of surviving hippocampal neuroprogenitors
      $125,519

      award amount

53. Klomp, Jennifer E

    Leads 1 award · $111,438

    • 1K99CA276700-01A1Department: NIH department code

      Mechanistic Basis for ERK in driving KRAS-dependent pancreatic cancer
      $111,438

      award amount

54. Flanigan, Meghan Elizabeth

    Leads 1 award · $107,869

    • 1K99AA030628-01A1Department: NIH department code

      Regulation of alcohol-induced social disturbances by lateral habenula serotonin receptors
      $107,869

      award amount

55. Haldane, Allan

    Leads 1 award · $98,865

    • 7R56DK135824-02Department: NIH department code

      Probing Mechanisms of Polycystin-1 Regulation Using Peptide Modulators Designed by Sequence- and Structure-Based Learning
      $98,865

      award amount

56. Kocak, Daniel Dewran

    Leads 1 award · $98,161

    • 1K99GM149931-01Department: NIH department code

      DRUG DISCOVERY BY DIRECTED EVOLUTION IN MAMMALIAN CELLS
      $98,161

      award amount

57. Gonzalez, Daniel

    Leads 1 award · $71,519

    • 5R01HD102949-03Department: NIH department code

      Application of Physiologically-Based Pharmacokinetic Modeling to Characterize Drug-Drug Interactions in Infants
      $71,519

      award amount

58. Pruitt, Kevin

    Leads 1 award · $65,081

    • 7R03AG080356-02Department: NIH department code

      Post-translational regulation of aromatase in aging
      $65,081

      award amount

59. Allen, Caitlin Gloeckner

    Leads 1 award · $42,000

    • 2R13CA261073-02Department: NIH department code

      Transdisciplinary Conference for Future Leaders in Precision Public Health
      $42,000

      award amount

60. Murvin, McKenzie

    Leads 1 award · $40,954

    • 1F31HD111292-01Department: NIH department code

      Dissecting mechanisms of gene silencing by the lncRNA Kcnq1ot1 in mouse trophoblast stem cells
      $40,954

      award amount

61. Bedard, Madigan

    Leads 1 award · $39,238

    • 1F31DA056211-01A1Department: NIH department code

      GABAergic alterations in the BNST to VTA circuit following morphine withdrawal
      $39,238

      award amount

62. Zarmer, Sandra

    Leads 1 award · $36,112

    • 5F31CA257224-03Department: NIH department code

      Identifying targets for combination therapy with FOLFIRINOX and investigating cell polarity loss as a potential driver of invasion in basal-like PDAC
      $36,112

      award amount

63. Zhu, Manhua

    Leads 1 award · $20,538

    • 5F31DA053064-03Department: NIH department code

      Impact of electronic nicotine vapor on mouse mesolimbic CRFR1 circuitry and motivated behavior
      $20,538

      award amount