Orthopedics at University of Pennsylvania

Leads a grant in this department

16 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Robert L Mauck

   Leads 3 awards · $1,641,732

   • 2R01AR075418-06Department: NIH department code

     Mechanical Regulation of Cell Fate and Multi-Scale Function in the Developing Meniscus

     Principal investigators: Robert L Mauck (contact PI), Lin Han, Nathaniel A. Dyment

     $643,499

     award amount
   • 5R01AR056624-15Department: NIH department code

     Dynamic Fibrous Scaffolds for Repairing Dense Connective Tissues

     Principal investigators: Robert L Mauck (contact PI), Jason A Burdick

     $516,327

     award amount
   • 5R01AR077362-13Department: NIH department code

     Engineered Developmental Microenvironments: Cartilage Formation and Maturation

     Principal investigators: Robert L Mauck (contact PI), Jason A Burdick

     $481,906

     award amount

   Also a principal investigator on 5R01AR077435-04, led by Lachlan James Smith; 5R01AR079875-02, led by Ling Qin; 5T32AR007132-48, led by Louis J Soslowsky.

2. Ling Qin

   Leads 3 awards · $1,365,716

   • 5R01AR079875-02Department: NIH department code

     Activation of endogenous progenitors via a nanoparticle-conjugated fibrous system to enhance meniscus repair

     Principal investigators: Ling Qin (contact PI), Robert L Mauck

     $466,547

     award amount
   • 5R01AG069401-04Department: NIH department code

     Control of bone physiology by a novel type of adipose cells
     $460,194

     award amount
   • 5R01AG067698-05Department: NIH department code

     EGFR signaling in osteoarthritis and treatment
     $438,975

     award amount

3. Nathaniel A. Dyment

   Leads 3 awards · $1,084,279

   • 1R01AR082810-01A1Department: NIH department code

     Localized small molecule delivery to improve tendon-to-bone integration following anterior cruciate ligament reconstruction

     Principal investigators: Nathaniel A. Dyment (contact PI), Andrew Frederic Kuntz

     $549,437

     award amount
   • 5R01AR076381-05Department: NIH department code

     Functional role and therapeutic potential of hedgehog signaling in tendon-to-bone repair
     $333,968

     award amount
   • 5R21AR081564-02Department: NIH department code

     Coordinated resident macrophage-tenocyte signaling in tendon formation
     $200,874

     award amount

   Also a principal investigator on 2R01AR075418-06, led by Robert L Mauck; 1R01HD113596-01A1, led by Joel D Boerckel; 5R01AR078790-04, led by Louis J Soslowsky.

4. Louis J Soslowsky

   Leads 4 awards · $1,079,607

   • 5T32AR007132-48Department: NIH department code

     Training Program in Musculoskeletal Research

     Principal investigators: Louis J Soslowsky (contact PI), Robert L Mauck

     $372,511

     award amount
   • 5R01AR078790-04Department: NIH department code

     Critical role of collagen XII in cell- and matrix-mediated mechanisms regulating acquisition of tendon structure and function in development and the injury response

     Principal investigators: Louis J Soslowsky (contact PI), Nathaniel A. Dyment

     $337,736

     award amount
   • 5R01AR080029-03Department: NIH department code

     Collagen III differential roles in temporal regulation of tendon healing across ages

     Principal investigators: Louis J Soslowsky (contact PI), Susan W Volk

     $337,434

     award amount
   • 3P50AR080581-02S1Department: NIH department code

     Achilles Tendinopathy Center of Research Translation
     $31,926

     award amount

5. Joel D Boerckel

   Leads 4 awards · $1,052,681

   • 1R01HD113596-01A1Department: NIH department code

     Effects of maternal exercise on fetal akinesia-impaired bone and joint development

     Principal investigators: Joel D Boerckel (contact PI), Nathaniel A. Dyment

     $523,064

     award amount
   • 5R01GM143400-03Department: NIH department code

     Single-component optogenetic tools to bidirectionally control RhoA in mechanotransduction
     $346,208

     award amount
   • 3R01GM143400-03S1Department: NIH department code

     Single-component optogenetic tools to bidirectionally control RhoA in mechanotransduction
     $137,556

     award amount
   • 3R01GM143400-02S1Department: NIH department code

     Single-component optogenetic tools to bidirectionally control RhoA in mechanotransduction
     $45,853

     award amount

6. Ernestina Schipani

   Leads 3 awards · $981,640

   • 5R01AR074079-06Department: NIH department code

     Mitochondria and TFAM in Osteoblast Biology
     $376,777

     award amount
   • 5R01HD112003-02Department: NIH department code

     Hypoxia and mitochondria in spine development and congenital scoliosis
     $345,881

     award amount
   • 5R01AR075770-04Department: NIH department code

     Regenerating Hyaline Cartilage Using Nanofibrous Hollow Microspheres and Synergizing TGF-beta and HIF

     Principal investigators: Ernestina Schipani (contact PI), Peter X Ma

     $258,982

     award amount

7. Josh Baxter

   Leads 4 awards · $906,054

   • 5R01AR078898-03Department: NIH department code

     Tendon loading profiles that promote healing in Achilles tendinopathy
     $435,674

     award amount
   • 5R01AR081062-03Department: NIH department code

     Defining neuromechanical mechanisms of Achilles tendinopathy

     Principal investigators: Josh Baxter (contact PI), Flavia Vitale

     $341,894

     award amount
   • 5K01AR075877-05Department: NIH department code

     Modifying muscle remodeling following Achilles tendon ruptures
     $103,814

     award amount
   • 3R01AR078898-03S1Department: NIH department code

     Tendon loading profiles that promote healing in Achilles tendinopathy
     $24,672

     award amount

8. Xiaowei Sherry Liu

   Leads 2 awards · $640,079

   • 5R01AR077598-04Department: NIH department code

     Leveraging modeling-based bone formation for osteoporosis treatment
     $411,954

     award amount
   • 2R56AR071718-06A1Department: NIH department code

     Osteocyte peri-lacunar/canalicular remodeling in maternal bone adaptation

     Principal investigators: Xiaowei Sherry Liu (contact PI), Liyun Wang

     $228,125

     award amount

9. Sarah E Gullbrand

   Leads 1 award · $605,253

   • 1R01AR083007-01A1Department: NIH department code

     Disc-Facet Crosstalk During Spinal Degeneration and Repair
     $605,253

     award amount

10. Lachlan James Smith

    Leads 2 awards · $558,519

    • 5R01AR077435-04Department: NIH department code

      Neutralizing the degenerate disc microenvironment to enhance the efficacy of therapeutic stem cells

      Principal investigators: Lachlan James Smith (contact PI), Neil Malhotra, Robert L Mauck

      $546,109

      award amount
    • 5R13AR082272-02Department: NIH department code

      ORS Spine Section Symposia: Enhancing Spine Research throughMentoring, Diversity and Collaboration
      $12,410

      award amount

11. Foteini Mourkioti

    Leads 2 awards · $411,775

    • 5R01AR075914-05Department: NIH department code

      Molecular mechanisms of telomere function in muscle stem cells
      $346,775

      award amount
    • 3R01AR075914-05S1Department: NIH department code

      Molecular mechanisms of telomere function in muscle stem cells
      $65,000

      award amount

12. Kyu Sang Joeng

    Leads 1 award · $346,775

    • 5R01AR079486-03Department: NIH department code

      The function of mTORC1/Stat3 signaling in the regulation of fibrovascular scar formation during tendon healing
      $346,775

      award amount

13. Su Chin Heo

    Leads 1 award · $126,495

    • 5K01AR077087-05Department: NIH department code

      Biophysical regulation of genome architecture in meniscus cells
      $126,495

      award amount

14. Jonathon Blank

    Leads 1 award · $74,828

    • 1F32AR082671-01A1Department: NIH department code

      Glycosaminoglycan-mediated fibril sliding and its role in fatigue-induced microdamage and rupture in aged and healing Achilles tendons
      $74,828

      award amount

15. Meghan Elizabeth Kupratis

    Leads 1 award · $73,828

    • 1F32AR084906-01Department: NIH department code

      Multiscale mechano-metabolic regulation of fibrous tissue homeostasis
      $73,828

      award amount

16. Michael William Hast

    Leads 1 award · $15,984

    • 5K25AR078383-04Department: NIH department code

      Modifying fragility fracture healing using a gradient-based mechanotransduction fixation approach
      $15,984

      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.

• Jason A Burdick

  Co-investigator on 5R01AR056624-15, led by Robert L Mauck; 5R01AR077362-13, led by Robert L Mauck

  From the FY2024 awards this person leads

  • University of Colorado · Miscellaneous (NIH department code, 2 awards)

• Lin Han

  Co-investigator on 2R01AR075418-06, led by Robert L Mauck

  From the FY2024 awards this person leads

  • Drexel University · Engineering (NIH department code, 1 award)
  • Drexel University (no department on record, 1 award)

• Andrew Frederic Kuntz

  Co-investigator on 1R01AR082810-01A1, led by Nathaniel A. Dyment

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Neil Malhotra

  Co-investigator on 5R01AR077435-04, led by Lachlan James Smith

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Flavia Vitale

  Co-investigator on 5R01AR081062-03, led by Josh Baxter

  From the FY2024 awards this person leads

  • University of Pennsylvania · Neurology (NIH department code, 1 award)

• Susan W Volk

  Co-investigator on 5R01AR080029-03, led by Louis J Soslowsky

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Peter X Ma

  Co-investigator on 5R01AR075770-04, led by Ernestina Schipani

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Liyun Wang

  Co-investigator on 2R56AR071718-06A1, led by Xiaowei Sherry Liu

  From the FY2024 awards this person leads

  • University of Delaware (no department on record, 1 award)