Pharmacology at University of Pittsburgh

Leads a grant in this department

47 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Xie, Wen

   Leads 3 awards · $1,630,081

   • 1R35ES030429-01Department: NIH department code

     Xenobiotic Receptors in Mediating the Environmental Effects on Human Disease and Morbidity
     $925,831

     award amount
   • 1R01DK117370-01A1Department: NIH department code

     PXR-Mediated Xenobiotic Response in the Pathogenesis Hemorrhagic Shock
     $352,125

     award amount
   • 5R01DK083952-09Department: NIH department code

     The AHR-FGF221 Axis in Hepatic Steatosis and Metobolic Syndrome
     $352,125

     award amount

2. Singh, Shivendra

   Leads 4 awards · $1,524,342

   • 1R01CA225716-01A1Department: NIH department code

     Biomarkers of Sulforaphane/Broccoli Sprout Extract in Prostate Cancer
     $494,138

     award amount
   • 1R01CA219180-01A1Department: NIH department code

     The Role of FoxQ1 in Breast Cancer Chemoprevention by Allium Constituents - R01CA219180
     $357,994

     award amount
   • 5R01CA101753-15Department: NIH department code

     Anticarcinogenic Effect of ITCs Against Prostate Cancer
     $336,105

     award amount
   • 5R01CA142604-10Department: NIH department code

     Breast Cancer Prevention by Ayurvedic Medicine Constituents
     $336,105

     award amount

3. Friedman, Peter A

   Leads 2 awards · $1,191,169

   • 5R01DK105811-04Department: NIH department code

     Hormonal Regulation of NHERF1 in Bone
     $603,220

     award amount
   • 5R01DK111427-03Department: NIH department code

     Functional Polarity of PTH Receptor Signaling: Cellular and Molecular Mechanisms
     $587,949

     award amount

4. Jackson, Edwin Kerry

   Leads 3 awards · $1,128,375

   • 5R01HL069846-17Department: NIH department code

     Role of Cardiac and Renal DPP4
     $391,250

     award amount
   • 5R01HL109002-08Department: NIH department code

     The Guanosine-Adenosine Mechanism
     $385,000

     award amount
   • 5R01DK091190-09Department: NIH department code

     Adenosine in Renal Sympathetic Neurotransmission
     $352,125

     award amount

5. Straub, Adam Carl

   Leads 2 awards · $1,001,022

   • 5R01HL133864-04Department: NIH department code

     Novel role of smooth muscle B5 reductase in Sickle Cell Disease
     $610,045

     award amount
   • 5R01HL128304-04Department: NIH department code

     Vascular Smooth Muscle and Blood Pressure Regulation By Cyb5R3²
     $390,977

     award amount

6. Levitan, Edwin S

   Leads 3 awards · $983,326

   • 5R01NS032385-23Department: NIH department code

     Dense-Core Vesicle Circulation, Capture and Synaptic Neuropeptide Release
     $540,865

     award amount
   • 1R21NS115023-01Department: NIH department code

     A New Method for Imaging Neuropeptide Release in the Brain
     $246,836

     award amount
   • 5R21NS106823-02Department: NIH department code

     Endoplasmic Reticulum NAD(P)H Dynamics in Dopamine Neurons
     $195,625

     award amount

7. Li, Song

   Leads 2 awards · $786,739

   • 5R01CA219399-03Department: NIH department code

     Immunostimulatory Nanocarrier for Breast Cancer Immunochemotherapy
     $440,990

     award amount
   • 5R01CA223788-02Department: NIH department code

     Nanotherapeutics for Synergistic Targeting of Myc in Prostate Cancer
     $345,749

     award amount

8. Zhang, Lin

   Leads 2 awards · $780,055

   • 1R01CA236271-01A1Department: NIH department code

     Role of necroptosis in colorectal cancer therapy
     $445,723

     award amount
   • 5R01CA203028-04Department: NIH department code

     Role of Mcl-1 degradation in colorecal cancer therapy
     $334,332

     award amount

9. Pagano, Patrick J

   Leads 2 awards · $766,611

   • 1R01HL142248-01A1Department: NIH department code

     Progressive degenerative role of Nox and thrombospondin-1 in the aging vasculature
     $581,804

     award amount
   • 5T32GM008424-25Department: NIH department code

     Predoctoral Training in Pharmacological Sciences
     $184,807

     award amount

10. Van Houten, Bennett

    Leads 2 awards · $753,686

    • 5R01ES019566-09Department: NIH department code

      DNA damage recognition by nucleotide excision repair proteins
      $389,377

      award amount
    • 5R01ES028686-02Department: NIH department code

      Damage Sensor role of UV-DDB during base excision repair
      $364,309

      award amount

11. Freeman, Bruce Alan

    Leads 1 award · $743,388

    • 5R01HL132550-04Department: NIH department code

      Anti-Inflammatory Lipid Mediators in Asthma
      $743,388

      award amount

12. Schopfer, Francisco Jose

    Leads 2 awards · $741,570

    • 5R01DK112854-02Department: NIH department code

      Predominant protective role in hepatic steatosis and obesity by fish oil-derived furans
      $396,123

      award amount
    • 5R01GM125944-02Department: NIH department code

      Formation, absorption, distribution, storage and protein targets to define activity of pleiotropic endogenous nitrated fatty acids
      $345,447

      award amount

13. Oesterreich, Steffi

    Leads 2 awards · $726,022

    • 5R01CA221303-02Department: NIH department code

      Mechanism-based strategies to target ER-mutant endocrine resistant breast cancer
      $382,045

      award amount
    • 5R01CA224909-02Department: NIH department code

      FGFR4: A druggable mediator of endocrine resistance in breast cancer
      $343,977

      award amount

14. Beckel, Jonathan M

    Leads 2 awards · $704,250

    • 5R01DK111382-03Department: NIH department code

      Parasympathetic and sympathetic mechanisms underlying bladder nociception
      $352,125

      award amount
    • 5R01DK117884-02Department: NIH department code

      Underlying mechanisms controlling urothelial ATP release and their contributions to urinary bladder physiology and pathophysiology
      $352,125

      award amount

15. Birder, Lori A

    Leads 1 award · $691,229

    • 1R56AG063753-01Department: NIH department code

      Role of Purine Dysregulation in the Underactive Bladder
      $691,229

      award amount

16. Opresko, Patricia L

    Leads 1 award · $523,668

    • 5R33ES025606-05Department: NIH department code

      ROS driven mitochondrial-telomere dysfunction during environmental stress
      $523,668

      award amount

17. Defranco, Donald B

    Leads 1 award · $449,936

    • 5R01HD087288-03Department: NIH department code

      Selective Glucocorticoid Action in the Developing Brain
      $449,936

      award amount

18. Zhang, Cheng

    Leads 2 awards · $439,950

    • 5R35GM128641-02Department: NIH department code

      Structure, pharmacology and signaling of G protein-coupled receptors (GPCRs) in inflammation
      $391,250

      award amount
    • 3R35GM128641-01S1Department: NIH department code

      Structure, pharmacology and signaling of G protein-coupled receptors (GPCRs) in inflammation
      $48,700

      award amount

19. Sant, Shilpa

    Leads 1 award · $431,871

    • 5R37CA232209-02Department: NIH department code

      Three-dimensional organoid models to study breast cancer progression
      $431,871

      award amount

20. Di Maio, Roberto

    Leads 1 award · $430,375

    • 1R21NS112787-01Department: NIH department code

      Protective actions of the anti-inflammatory drug candidate 10-nitro-oleic acid in Parkinson’s disease
      $430,375

      award amount

21. Vilardaga, Jean-Pierre

    Leads 1 award · $429,297

    • 5R01DK116780-02Department: NIH department code

      Structural Basis of PTH Receptor Function
      $429,297

      award amount

22. Johnston, Paul A.

    Leads 1 award · $400,283

    • 1R01CA229836-01A1Department: NIH department code

      qHTS of Patient Derived HCC Models to Identify Novel Probes/Therapeutic Agents
      $400,283

      award amount

23. Palladino, Michael John

    Leads 2 awards · $397,332

    • 5R21AG059385-02Department: NIH department code

      Regulators of cytosolic protein quality control in aging and disease
      $201,707

      award amount
    • 5R21AG059386-02Department: NIH department code

      Genetic modulation of mitochondrial function
      $195,625

      award amount

24. Altschuler, Daniel L

    Leads 1 award · $391,250

    • 1R01GM130612-01A1Department: NIH department code

      Role of soluble adenylyl cyclase in TSH biology
      $391,250

      award amount

25. Jacob, Tija C.

    Leads 1 award · $391,250

    • 1R01MH114908-01A1Department: NIH department code

      Benzodiazepine treatment induced neuroplasticity
      $391,250

      award amount

26. Shiva, Sruti

    Leads 1 award · $391,250

    • 5R01HL133003-03Department: NIH department code

      Heme-induced platelet mtROS drives TSP1 release to accelerate PH pathogenesis
      $391,250

      award amount

27. Ma, Xiaochao

    Leads 1 award · $382,628

    • 5R01AI131983-03Department: NIH department code

      Pharmacoenhancers for antiretroviral therapy: safety and future development
      $382,628

      award amount

28. Wang, Lirong

    Leads 1 award · $377,443

    • 1R56AG062493-01Department: NIH department code

      Personalized Combination Therapy for AD with Common Comorbidities
      $377,443

      award amount

29. McDermott, Lee A

    Leads 1 award · $375,111

    • 5R21NS107785-02Department: NIH department code

      20-HETE Formation Inhibitors in Cardiac Arrest
      $375,111

      award amount

30. Wang, Qiming Jane

    Leads 1 award · $368,279

    • 1R01CA229431-01A1Department: NIH department code

      A novel mitotic regulatory axis in neuroendocrine prostate cancer
      $368,279

      award amount

31. Yang, Da

    Leads 1 award · $347,253

    • 5R01CA222274-02Department: NIH department code

      The oncogenic role of EPIC1MYC axis in breast cancer
      $347,253

      award amount

32. Frahm, Krystle Anne

    Leads 2 awards · $344,028

    • 1R21DK121266-01A1Department: NIH department code

      The Role of a Novel Obesity-Risk Variant on Hypothalamic Regulation of Energy Homeostasis
      $195,625

      award amount
    • 5K01DK115543-03Department: NIH department code

      Impact of CREBRF and its obesity-risk variant on hypothalamic glucocorticoid and neuroendocrine output using molecular, cellular, and physiological approaches.
      $148,403

      award amount

33. Bisello, Alessandro

    Leads 1 award · $343,391

    • 5R01HL136382-03Department: NIH department code

      Regulation of oxidative stress and vascular remodeling by EBP50
      $343,391

      award amount

34. Neumann, Carola Anke

    Leads 1 award · $341,974

    • 1R56CA233817-01A1Department: NIH department code

      Inhibition of DNA double strand break repair in TNBC by nitro-fatty acids
      $341,974

      award amount

35. O'Sullivan, Roderick

    Leads 1 award · $338,612

    • 5R01CA207209-04Department: NIH department code

      Inhibition of the ALT pathway by interfering with Poly-ADP-Ribose metabolism
      $338,612

      award amount

36. Jiang, Yu

    Leads 1 award · $313,000

    • 1R01GM132127-01Department: NIH department code

      Mechanisms of Signaling Protein Retention in the Primary Cilium
      $313,000

      award amount

37. Fernandez, Christian Antonio

    Leads 1 award · $312,527

    • 5R01CA216815-03Department: NIH department code

      Improving the disposition of antileukemic asparaginase after drug-induced immunotoxicity
      $312,527

      award amount

38. Galbiati, Ferruccio

    Leads 1 award · $303,610

    • 5R01CA205165-03Department: NIH department code

      Mechanisms that control the progression from premalignant lesions to adenocarcinomas in the lung
      $303,610

      award amount

39. Furey, William F

    Leads 1 award · $301,263

    • 5R01GM121469-03Department: NIH department code

      Pyruvate Dehydrogenase Assembly, Structure & Function
      $301,263

      award amount

40. Volonte, Daniela

    Leads 1 award · $234,750

    • 1R21AG061614-01Department: NIH department code

      PTRF, a novel regulator of oncogene-induced senescence
      $234,750

      award amount

41. Parise, Robert

    Leads 1 award · $181,103

    • 5R50CA211241-04Department: NIH department code

      Cancer Pharmacokinetics Research Specialist
      $181,103

      award amount

42. Vitturi, Dario A

    Leads 1 award · $160,756

    • 5K01HL133331-04Department: NIH department code

      Protection against sickle cell disease nephropathy by nitrated fatty acids
      $160,756

      award amount

43. Hernandez, Inmaculada

    Leads 1 award · $159,504

    • 5K01HL142847-02Department: NIH department code

      Patient and System-Level Determinants of Oral Anticoagulation Use in Atrial Fibrillation
      $159,504

      award amount

44. Tasdemir, Nilgun

    Leads 1 award · $128,012

    • 1K99CA237736-01Department: NIH department code

      Non-canonical FADD signaling as a genetic driver of invasive lobular carcinoma
      $128,012

      award amount

45. Clark, Lisa Jean

    Leads 1 award · $45,016

    • 1F31AR074843-01Department: NIH department code

      Structural Mechanisms of parathyroid hormone receptor signaling through Gs
      $45,016

      award amount

46. Buchan, Greg

    Leads 1 award · $23,064

    • 5F31HL142171-02Department: NIH department code

      Evaluating the therapeutic potential of electrophilic fatty acid derivatives for influenza-induced lung injury
      $23,064

      award amount

47. Lorenz-Guertin, Joshua

    Leads 1 award · $18,670

    • 5F31MH117839-02Department: NIH department code

      Diazepam induces synaptic GABA type A receptor plasticity via multiple trafficking mechanisms
      $18,670

      award amount