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FY2025 NIH awards · Principal investigators

Pharmacology at University of Pittsburgh

Pittsburgh, PA

Funding
$32.2M
$32,214,127
Awards
70
FY2025 NIH awards in Pharmacology
Principal investigators
70
52 lead a grant here, 18 co-investigators
Department rank
#4
of 127 · Ranking
  • NIH names only the principal investigators on an award, so this page lists only them. The department is the award's: it is where ScienceDex counts the award, not a list of the department's members.
  • These are the awards in the Pharmacology row of the University of Pittsburgh page.

Leads a grant in this department

52 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

  1. Laura Ellen Pascal

    Leads 1 award · $2,482,346

    • 1R01DK139055-01A1Department: NIH department code
      ZC3H4 Driven Prostate Tissue Remodeling Triggered by Maladaptive Metabolic and Signaling Pathways
      $2,482,346
      award amount

  2. Song Li

    Leads 3 awards · $1,520,994

    • 1R01CA295774-01Department: NIH department code
      Targeting iRhom to Improve Colon Cancer Immunochemotherapy
      $546,625
      award amount
    • 5R01CA278608-03Department: NIH department code
      Nanoparticles-mediated combination therapy for breast cancer
      $501,746
      award amount
    • 5R01CA270623-03Department: NIH department code
      Combination Therapy for Pancreatic Cancer
      $472,623
      award amount

  3. Adam Carl Straub

    Leads 2 awards · $1,485,492

    • 5R35HL161177-04Department: NIH department code
      Basic and Translational Studies in Redox Regulation of Cardiovascular Physiology and Disease
      $948,100
      award amount
    • 5R01NS129613-03Department: NIH department code
      Cerebral Vascular Redox Regulation in Stroke

      Principal investigators: Adam Carl Straub (contact PI), Dandan Sun, Katherine C Wood

      $537,392
      award amount

  4. Michael John Palladino

    Leads 3 awards · $1,430,725

    • 5R01HD104346-05Department: NIH department code
      High-content screening for TPI Deficiency therapeutics

      Principal investigators: Michael John Palladino (contact PI), Andreas Vogt

      $548,111
      award amount
    • 5R01HD105311-05Department: NIH department code
      Developing the first TPI Df therapeutics

      Principal investigators: Michael John Palladino (contact PI), Andreas Vogt

      $524,864
      award amount
    • 5R01NS129659-02Department: NIH department code
      Mechanisms of Circadian Rhythm Modulation by Metabolic Disease and Dietary Therapy
      $357,750
      award amount

  5. Katherine Marie Aird

    Leads 3 awards · $1,396,106

    • 1R01CA298386-01Department: NIH department code
      Acylcarnitine Metabolism in Ovarian Cancer Chemoresistance

      Principal investigators: Katherine Marie Aird (contact PI), Nathaniel W. Snyder

      $686,654
      award amount
    • 1R01CA301573-01Department: NIH department code
      Cell intrinsic and extrinsic effects of zinc metabolism in therapy resistant melanoma

      Principal investigators: Katherine Marie Aird (contact PI), Nadine Hempel, Raquel Buj Gomez

      $400,461
      award amount
    • 5R01CA259111-05Department: NIH department code
      Metabolic and epigenetic reprogramming in cyclin E high ovarian cancer

      Principal investigators: Katherine Marie Aird (contact PI), Nathaniel W. Snyder

      $308,991
      award amount

  6. Patricia L Opresko

    Leads 2 awards · $1,396,040

    • 5R35ES030396-07Department: NIH department code
      Excision Repair of Environmental Telomere Damage
      $931,280
      award amount
    • 5R01CA207342-08Department: NIH department code
      Roles of Telomeric Oxidative DNA Lesions in Telomere Length Regulation

      Principal investigators: Patricia L Opresko (contact PI), Sua Myong

      $464,760
      award amount

  7. Wen Xie

    Leads 2 awards · $1,189,778

    • 5R35ES030429-07Department: NIH department code
      Xenobiotic Receptors in Mediating the Environmental Effects on Human Disease and Morbidity
      $814,679
      award amount
    • 5R01DK135538-03Department: NIH department code
      Cellular and Metabolic Basis of the Role of CYP1B1 in Liver Fibrosis
      $375,099
      award amount

  8. Da Yang

    Leads 3 awards · $1,163,180

    • 5R01CA282704-03Department: NIH department code
      Enhancer RNAs Boost MYC-Chromatin Interaction to Regulate Gene Expression and Tumorigenesis
      $408,907
      award amount
    • 5R01CA272866-03Department: NIH department code
      LncRNA EPIC1 induces immunotherapy resistance by activating EZH2 in breast cancer
      $378,023
      award amount
    • 5R01CA255196-05Department: NIH department code
      A novel lncRNA-responsive and xenobiotic receptor-mediated regulation of drug metabolism and disposition
      $376,250
      award amount

  9. Francisco Jose Schopfer

    Leads 2 awards · $1,071,229

    • 1R01AR084311-01A1Department: NIH department code
      Impact of dietary lipid components on phototherapy used to treat inflammatory skin conditions

      Principal investigators: Francisco Jose Schopfer (contact PI), Alicia R Mathers

      $673,729
      award amount
    • 5R01GM125944-08Department: NIH department code
      Formation and metabolism of nitrated fatty acids
      $397,500
      award amount

    Also a principal investigator on 2T32GM133332-06, led by Tija C. Jacob.

  10. Bennett Van Houten

    Leads 1 award · $906,257

    • 5R35ES031638-06Department: NIH department code
      Watching cooperative interactions between base and nucleotide excision repair proteins
      $906,257
      award amount

  11. Mohamed Trebak

    Leads 1 award · $873,455

    • 5R35HL150778-06Department: NIH department code
      Ca2+ signaling Networks in Health and Disease
      $873,455
      award amount

  12. Mark T. Miedel

    Leads 2 awards · $837,263

    • 5R01DK135606-02Department: NIH department code
      Implementing A QSP Platform to Predict and Test Drugs for Metabolic Associated Fatty Liver Disease Genetic Variants in an iPSC-cell Based Human Biomimetic Liver Microphysiology System

      Principal investigators: Mark T. Miedel (contact PI), Alejandro Soto-Gutierrez

      $598,763
      award amount
    • 5UH3TR004124-04Department: NIH department code
      Re-engineering a human 3D liver tissue model for non-alcoholic fatty liver disease for drug screening
      $238,500
      award amount

  13. Roderick O'Sullivan

    Leads 2 awards · $831,719

    • 5R01CA262316-04Department: NIH department code
      Co-Regulation of Alternative Lengthening of Telomeres and Chromatin Dynamics in ATRX-DAXX deficient cancer cells
      $463,559
      award amount
    • 5R01CA207209-09Department: NIH department code
      Inhibition of the ALT pathway by interfering with Poly-ADP-Ribose metabolism
      $368,160
      award amount

  14. Cheng Zhang

    Leads 2 awards · $828,738

    • 5R35GM128641-07Department: NIH department code
      Structure, pharmacology and signaling of G protein-coupled receptors (GPCRs) in inflammation
      $419,909
      award amount
    • 1R21CA299543-01Department: NIH department code
      Develop positive allosteric modulators to enhance XCR1 signaling in cancer
      $408,829
      award amount

    Also a principal investigator on 5U01DA052329-05, led by Xiang-Qun Xie.

  15. Edwin S Levitan

    Leads 1 award · $796,375

    • 5R01NS032385-29Department: NIH department code
      Compartmental, rhythmic and plastic neuropeptide release
      $796,375
      award amount

  16. Satdarshan Singh Monga

    Leads 1 award · $763,804

    • 2R01DK062277-21A1Department: NIH department code
      Role of Wnt-Beta-catenin in liver development and metabolic zonation
      $763,804
      award amount

    Also a principal investigator on 5R01DK103775-09, led by Kari N Nejak-Bowen.

  17. Stacy Lynn Gelhaus

    Leads 1 award · $696,473

    • 1R01HL176502-01Department: NIH department code
      Microbial-derived metabolites potentiate airway hyperresponsiveness in obesity-associated asthma

      Principal investigators: Stacy Lynn Gelhaus (contact PI), Michelle Lynn Manni

      $696,473
      award amount

  18. Michael Oertel

    Leads 1 award · $683,339

    • 5R01DK140405-02Department: NIH department code
      Combating Chronic Liver Diseases via Understanding and Engineering Cell Competition and Fitness

      Principal investigators: Michael Oertel (contact PI), Mo Reza Ebrahimkhani

      $683,339
      award amount

  19. Paul A. Johnston

    Leads 1 award · $652,558

    • 1R01CA297848-01Department: NIH department code
      Cell-Based HTS Campaign to Identify Negative Allosteric Modulators of the Leukemia-associated Tyrosine Kinase, BTK”.

      Principal investigators: Paul A. Johnston (contact PI), Thomas E. Smithgall

      $652,558
      award amount

  20. Junmei Wang

    Leads 2 awards · $645,200

    • 5R01GM147673-04Department: NIH department code
      New Generation of General AMBER Force Field for Biomedical Research

      Principal investigators: Junmei Wang (contact PI), Wei Yang

      $327,200
      award amount
    • 5R01GM149705-03Department: NIH department code
      AI-Powered Biased Ligand Design
      $318,000
      award amount

  21. Xiang-Qun Xie

    Leads 1 award · $633,135

    • 5U01DA052329-05Department: NIH department code
      Cannabinoid CB2 Receptor Structure and Allosteric Modulators

      Principal investigators: Xiang-Qun Xie (contact PI), Cheng Zhang

      $633,135
      award amount

  22. Jean-Pierre Vilardaga

    Leads 1 award · $606,024

    • 5R01DK116780-07Department: NIH department code
      Structure and function of PTH class B GPCR

      Principal investigators: Jean-Pierre Vilardaga (contact PI), Ivet Bahar

      $606,024
      award amount

  23. Marco Fazzari

    Leads 1 award · $601,041

    • 5R01HL162787-03Department: NIH department code
      Nitro-nitrate fatty acid derivatives as novel cGMP-dependent and cGMP-independent signaling mediators
      $601,041
      award amount

  24. Kari N Nejak-Bowen

    Leads 1 award · $596,342

    • 5R01DK103775-09Department: NIH department code
      Role and regulation of beta-catenin in cholestatic liver disease

      Principal investigators: Kari N Nejak-Bowen (contact PI), Satdarshan Singh Monga

      $596,342
      award amount

  25. Adrian V Lee

    Leads 1 award · $579,181

    • 5R01CA256161-05Department: NIH department code
      Estrogen receptor fusions genes as drivers of endocrine resistance in breast cancer

      Principal investigators: Adrian V Lee (contact PI), Steffi Oesterreich

      $579,181
      award amount

    Also a principal investigator on 5R01CA252378-05, led by Steffi Oesterreich.

  26. Sandra L Kane-Gill

    Leads 1 award · $560,084

    • 5R01DK121730-05Department: NIH department code
      (MEnD-AKI) Multicenter Implementation of an Electronic Decision Support System for Drug-associated AKI

      Principal investigators: Sandra L Kane-Gill (contact PI), Azra Bihorac

      $560,084
      award amount

  27. Donald B Defranco

    Leads 1 award · $550,615

  28. Steffi Oesterreich

    Leads 1 award · $527,799

    • 5R01CA252378-05Department: NIH department code
      Credentialing Models of Invasive Lobular Breast Cancer for Translational Research

      Principal investigators: Steffi Oesterreich (contact PI), Adrian V Lee

      $527,799
      award amount

    Also a principal investigator on 5R01CA256161-05, led by Adrian V Lee.

  29. Aaron Sriram Devanathan

    Leads 1 award · $522,167

    • 5DP1HL174180-02Department: NIH department code
      Multiomics and Antiretroviral Drug Exposure for assessing Metabolic Effects (MADE-FOR-ME)
      $522,167
      award amount

  30. Yael Nechemia-Arbely

    Leads 2 awards · $440,031

    • 5R35GM142717-05Department: NIH department code
      Mechanisms of epigenetic assembly, maintenance and propagation of human centromeres
      $397,500
      award amount
    • 3R35GM142717-04S1Department: NIH department code
      Supplement to Promote Diversity: Mechanisms of epigenetic assembly, maintenance and propagation of human centromeres
      $42,531
      award amount

  31. Shuchang Silvia Liu

    Leads 1 award · $437,250

    • 1R35GM159862-01Department: NIH department code
      Advanced computational approaches for single-cell multi-omics integration
      $437,250
      award amount

  32. Reben Raeman

    Leads 1 award · $423,551

    • 5R01DK124351-05Department: NIH department code
      Mechanisms underlying hepatic immune cell recruitment in nonalcoholic fatty liver disease
      $423,551
      award amount

  33. Elise Fouquerel

    Leads 1 award · $397,500

    • 5R35GM142982-06Department: NIH department code
      Mechanistic insight into oxidative stress-mediated genome instability
      $397,500
      award amount

  34. Jonathan M Beckel

    Leads 1 award · $397,500

    • 5R01DK136505-03Department: NIH department code
      Characterization of Hypogastric Afferent Pathway Involved in Urinary Bladder Function and Dysfunction
      $397,500
      award amount

  35. Christian Antonio Fernandez

    Leads 1 award · $396,750

    • 5R01DK140079-02Department: NIH department code
      Mechanistic Study of PEG-asparaginase-Induced Liver Injury
      $396,750
      award amount

  36. Daniel L Altschuler

    Leads 1 award · $389,550

    • 5R01GM148449-03Department: NIH department code
      Novel mechanisms in the control of cAMP dynamics
      $389,550
      award amount

  37. Simone Brixius-Anderko

    Leads 1 award · $376,787

    • 5R35GM155319-02Department: NIH department code
      STUDIES ON FATTY ACID METABOLIZING CYTOCHROME P450 ENZYMES
      $376,787
      award amount

  38. Xiaochao Ma

    Leads 1 award · $340,040

    • 5R01DK126875-05Department: NIH department code
      The ABCG2 transporter in protoporphyrin IX disposition: from toxicity to therapy
      $340,040
      award amount

  39. Wei Zhang

    Leads 1 award · $249,000

    • 5R00GM141269-04Department: NIH department code
      Light triggered materials for on-demand local anesthesia and tissue adhesive dissolution
      $249,000
      award amount

  40. Patrick J Pagano

    Leads 1 award · $238,500

    • 5R21AG089718-02Department: NIH department code
      NOX2 Small Molecule Inhibitors as a Therapeutic Strategy in the Treatment of Alzheimer’s Disease

      Principal investigators: Patrick J Pagano (contact PI), Alberto L Vazquez

      $238,500
      award amount

  41. Michelle M Williams

    Leads 1 award · $232,955

    • 5R00CA266748-04Department: NIH department code
      Targeting heme metabolism to initiate an immune response against breast cancer liver metastasis
      $232,955
      award amount

  42. Tija C. Jacob

    Leads 1 award · $213,180

    • 2T32GM133332-06Department: NIH department code
      Predoctoral Training in Pharmacological Sciences

      Principal investigators: Tija C. Jacob (contact PI), Francisco Jose Schopfer

      $213,180
      award amount

  43. Matthew Allen Schaich

    Leads 2 awards · $186,823

    • 1K99ES036599-01A1Department: NIH department code
      Dynamics of oxidative DNA demethylation from duplex DNA to chromatin
      $127,384
      award amount
    • 5F32ES034982-02Department: NIH department code
      DNA repair pathway coordination during damage processing
      $59,439
      award amount

  44. Robert Parise

    Leads 1 award · $168,777

    • 5R50CA211241-10Department: NIH department code
      Cancer Pharmacokinetics Research Specialist
      $168,777
      award amount

  45. Viet Hoang Man

    Leads 1 award · $147,285

    • 5K25AG070277-05Department: NIH department code
      Development of novel computational protocols to study amyloid oligomerization
      $147,285
      award amount

  46. Yue Wang

    Leads 1 award · $121,857

    • 1K99CA297120-01A1Department: NIH department code
      Systematically Investigate Anti-Cancer Drug’s Modulation on T Cells in Tumor Microenvironment
      $121,857
      award amount

  47. Jie Bin Liu

    Leads 1 award · $54,538

    • 5F30CA278319-03Department: NIH department code
      Characterizing and Targeting ERBB2 Mutations in Invasive Lobular Carcinoma
      $54,538
      award amount

  48. Sofya Savransky

    Leads 1 award · $49,538

    • 5F31DK136222-02Department: NIH department code
      The role of cell surface glycosaminoglycans (GAGs) in PTHrP bias signaling
      $49,538
      award amount

  49. Yin Zhu

    Leads 1 award · $49,538

    • 1F31DK141128-01A1Department: NIH department code
      Mechanistic studies of amino acid deprivation-induced hepatic fibrosis
      $49,538
      award amount

  50. Nicole Colussi

    Leads 1 award · $40,100

    • 5F31HL172595-02Department: NIH department code
      Bridging the gap of endogenous nitro-conjugated linoleic acid formation and signaling
      $40,100
      award amount

  51. Christian J Goossen

    Leads 1 award · $32,618

    • 5F31HL167563-02Department: NIH department code
      Endothelial NOX1-Mediated AMPKa1 Propagates Hypoxia-Induced Pulmonary Hypertension via the CIP/KIP family of CDK inhibitors
      $32,618
      award amount

  52. Anne Wondisford

    Leads 1 award · $3,000

    • 3F30CA278287-02S1Department: NIH department code
      Understanding the impact of DNA ADP-ribosylation on telomere function in cancer cells
      $3,000
      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.