Pharmacology at University of Pittsburgh

Leads a grant in this department

49 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Adam Carl Straub

   Leads 3 awards · $2,051,740

   • 5R35HL161177-03Department: NIH department code

     Basic and Translational Studies in Redox Regulation of Cardiovascular Physiology and Disease
     $929,138

     award amount
   • 5R01NS129613-02Department: NIH department code

     Cerebral Vascular Redox Regulation in Stroke

     Principal investigators: Adam Carl Straub (contact PI), Dandan Sun, Katherine C Wood

     $597,103

     award amount
   • 5R01HL153532-04Department: NIH department code

     Role of Xanthine Oxidase in Heme-induced Vascular Dysfunction

     Principal investigators: Adam Carl Straub (contact PI), Eric Eugene Kelley

     $525,499

     award amount

2. Michael John Palladino

   Leads 3 awards · $1,474,188

   • 5R01HD104346-04Department: NIH department code

     High-content screening for TPI Deficiency therapeutics

     Principal investigators: Michael John Palladino (contact PI), Andreas Vogt

     $550,305

     award amount
   • 5R01HD105311-04Department: NIH department code

     Developing the first TPI Df therapeutics

     Principal investigators: Michael John Palladino (contact PI), Andreas Vogt

     $526,383

     award amount
   • 1R01NS129659-01A1Department: NIH department code

     Mechanisms of Circadian Rhythm Modulation by Metabolic Disease and Dietary Therapy
     $397,500

     award amount

3. Patricia L Opresko

   Leads 4 awards · $1,471,179

   • 5R35ES030396-06Department: NIH department code

     Excision Repair of Environmental Telomere Damage
     $931,280

     award amount
   • 5R01CA207342-07Department: NIH department code

     Roles of Telomeric Oxidative DNA Lesions in Telomere Length Regulation

     Principal investigators: Patricia L Opresko (contact PI), Sua Myong

     $441,523

     award amount
   • 3R35ES030396-06S1Department: NIH department code

     Excision Repair of Environmental Telomere Damage
     $78,701

     award amount
   • 3R35ES030396-05S1Department: NIH department code

     Supplement to Promote Diversity
     $19,675

     award amount

4. Michael Oertel

   Leads 2 awards · $1,278,907

   • 1R01DK140405-01Department: NIH department code

     Combating Chronic Liver Diseases via Understanding and Engineering Cell Competition and Fitness

     Principal investigators: Michael Oertel (contact PI), Mo Reza Ebrahimkhani

     $683,339

     award amount
   • 5R01DK130949-04Department: NIH department code

     Blocking hepatocyte senescence as a novel therapeutic strategy for chronic liver diseases

     Principal investigators: Michael Oertel (contact PI), Reben Raeman

     $595,568

     award amount

5. Wen Xie

   Leads 2 awards · $1,227,306

   • 5R35ES030429-06Department: NIH department code

     Xenobiotic Receptors in Mediating the Environmental Effects on Human Disease and Morbidity
     $827,199

     award amount
   • 5R01DK135538-02Department: NIH department code

     Cellular and Metabolic Basis of the Role of CYP1B1 in Liver Fibrosis
     $400,107

     award amount

6. Da Yang

   Leads 3 awards · $1,122,192

   • 5R01CA282704-02Department: NIH department code

     Enhancer RNAs Boost MYC-Chromatin Interaction to Regulate Gene Expression and Tumorigenesis
     $399,745

     award amount
   • 5R01CA272866-02Department: NIH department code

     LncRNA EPIC1 induces immunotherapy resistance by activating EZH2 in breast cancer
     $365,009

     award amount
   • 5R01CA255196-04Department: NIH department code

     A novel lncRNA-responsive and xenobiotic receptor-mediated regulation of drug metabolism and disposition
     $357,438

     award amount

7. Katherine Marie Aird

   Leads 3 awards · $1,037,324

   • 5R01CA259111-04Department: NIH department code

     Metabolic and epigenetic reprogramming in cyclin E high ovarian cancer

     Principal investigators: Katherine Marie Aird (contact PI), Nathaniel W. Snyder

     $504,676

     award amount
   • 5R37CA240625-05Department: NIH department code

     Investigating p16 Loss in Pro-tumorigenic Metabolism
     $333,898

     award amount
   • 3R01CA259111-04S1Department: NIH department code

     Metabolic and epigenetic reprogramming in cyclin E high ovarian cancer

     Principal investigators: Katherine Marie Aird (contact PI), Nathaniel W. Snyder

     $198,750

     award amount

8. Kari N Nejak-Bowen

   Leads 2 awards · $1,035,938

   • 5R01DK103775-08Department: NIH department code

     Role and regulation of beta-catenin in cholestatic liver disease

     Principal investigators: Kari N Nejak-Bowen (contact PI), Satdarshan Singh Monga

     $615,393

     award amount
   • 5R01DK124412-05Department: NIH department code

     Beta-catenin inhibition as a novel therapeutic strategy for porphyria
     $420,545

     award amount

9. Song Li

   Leads 2 awards · $925,609

   • 5R01CA278608-02Department: NIH department code

     Nanoparticles-mediated combination therapy for breast cancer
     $476,617

     award amount
   • 5R01CA270623-02Department: NIH department code

     Combination Therapy for Pancreatic Cancer
     $448,992

     award amount

10. Bennett Van Houten

    Leads 1 award · $906,257

    • 5R35ES031638-05Department: NIH department code

      Watching cooperative interactions between base and nucleotide excision repair proteins
      $906,257

      award amount

11. Mohamed Trebak

    Leads 1 award · $871,274

    • 5R35HL150778-05Department: NIH department code

      Ca2+ signaling Networks in Health and Disease
      $871,274

      award amount

12. Satdarshan Singh Monga

    Leads 2 awards · $805,785

    • 5R01CA251155-05Department: NIH department code

      Targeting tumor metabolism and immune environment via beta-catenin: Towards precision medicine in HCC

      Principal investigators: Satdarshan Singh Monga (contact PI), Amaia Lujambio

      $589,164

      award amount
    • 5T32EB001026-20Department: NIH department code

      Cellular Approaches to Tissue Engineering and Regeneration

      Principal investigators: Satdarshan Singh Monga (contact PI), Andrew W Duncan

      $216,621

      award amount

    Also a principal investigator on 5R01DK103775-08, led by Kari N Nejak-Bowen.

13. Roderick O'Sullivan

    Leads 2 awards · $790,133

    • 5R01CA262316-03Department: NIH department code

      Co-Regulation of Alternative Lengthening of Telomeres and Chromatin Dynamics in ATRX-DAXX deficient cancer cells
      $440,381

      award amount
    • 5R01CA207209-08Department: NIH department code

      Inhibition of the ALT pathway by interfering with Poly-ADP-Ribose metabolism
      $349,752

      award amount

14. Edwin S Levitan

    Leads 1 award · $772,484

    • 5R01NS032385-28Department: NIH department code

      Compartmental, rhythmic and plastic neuropeptide release
      $772,484

      award amount

15. Cheng Zhang

    Leads 2 awards · $665,864

    • 2R35GM128641-06Department: NIH department code

      Structure, pharmacology and signaling of G protein-coupled receptors (GPCRs) in inflammation
      $434,659

      award amount
    • 3R35GM128641-06S1Department: NIH department code

      Structure, pharmacology and signaling of G protein-coupled receptors (GPCRs) in inflammation
      $231,205

      award amount

    Also a principal investigator on 5R01DA052329-04, led by Xiang-Qun Xie.

16. Junmei Wang

    Leads 2 awards · $646,914

    • 5R01GM147673-03Department: NIH department code

      New Generation of General AMBER Force Field for Biomedical Research

      Principal investigators: Junmei Wang (contact PI), Wei Yang

      $328,914

      award amount
    • 5R01GM149705-02Department: NIH department code

      AI-Powered Biased Ligand Design
      $318,000

      award amount

17. Xiang-Qun Xie

    Leads 1 award · $633,135

    • 5R01DA052329-04Department: NIH department code

      Cannabinoid CB2 Receptor Structure and Allosteric Modulators

      Principal investigators: Xiang-Qun Xie (contact PI), Cheng Zhang

      $633,135

      award amount

18. Jean-Pierre Vilardaga

    Leads 1 award · $612,966

    • 5R01DK116780-06Department: NIH department code

      Structure and function of PTH class B GPCR

      Principal investigators: Jean-Pierre Vilardaga (contact PI), Ivet Bahar

      $612,966

      award amount

19. Marco Fazzari

    Leads 1 award · $589,019

    • 5R01HL162787-02Department: NIH department code

      Nitro-nitrate fatty acid derivatives as novel cGMP-dependent and cGMP-independent signaling mediators
      $589,019

      award amount

20. Daniel L Altschuler

    Leads 2 awards · $588,594

    • 5R01GM148449-02Department: NIH department code

      Novel mechanisms in the control of cAMP dynamics
      $389,550

      award amount
    • 3R01GM148449-01A1S1Department: NIH department code

      Novel mechanisms in the control of cAMP dynamics
      $199,044

      award amount

21. Donald B Defranco

    Leads 1 award · $579,211

    • 5R01HD104215-04Department: NIH department code

      A Safer Glucocorticoid to Treat Neonatal Lung Injury with Limited Adverse Neurologic Effects

      Principal investigators: Donald B Defranco (contact PI), A Paula Monaghan-Nichols, Venkatesh Sampath

      $579,211

      award amount

22. Sandra L Kane-Gill

    Leads 1 award · $561,234

    • 5R01DK121730-04Department: NIH department code

      (MEnD-AKI) Multicenter Implementation of an Electronic Decision Support System for Drug-associated AKI

      Principal investigators: Sandra L Kane-Gill (contact PI), Azra Bihorac

      $561,234

      award amount

23. Adrian V Lee

    Leads 1 award · $550,223

    • 5R01CA256161-04Department: NIH department code

      Estrogen receptor fusions genes as drivers of endocrine resistance in breast cancer

      Principal investigators: Adrian V Lee (contact PI), Steffi Oesterreich

      $550,223

      award amount

    Also a principal investigator on 5R01CA252378-04, led by Steffi Oesterreich.

24. Aaron Sriram Devanathan

    Leads 1 award · $538,800

    • 1DP1HL174180-01Department: NIH department code

      Multiomics and Antiretroviral Drug Exposure for assessing Metabolic Effects (MADE-FOR-ME)
      $538,800

      award amount

25. Francisco Jose Schopfer

    Leads 2 awards · $510,503

    • 5R01GM125944-07Department: NIH department code

      Formation and metabolism of nitrated fatty acids
      $397,500

      award amount
    • 3R01GM125944-07S1Department: NIH department code

      Formation and metabolism of nitrated fatty acids
      $113,003

      award amount

26. Jan Hendrik Beumer

    Leads 1 award · $483,938

    • 5U24CA247643-05Department: NIH department code

      PITT-CAL ETCTN PK Resource Laboratory

      Principal investigators: Jan Hendrik Beumer (contact PI), Timothy W Synold

      $483,938

      award amount

27. Michelle Lynn Manni

    Leads 1 award · $409,176

    • 5R01HL146445-05Department: NIH department code

      Immune Mediators of IL-22 Signaling Alter Allergic Airway Disease
      $409,176

      award amount

28. Reben Raeman

    Leads 1 award · $406,609

    • 5R01DK124351-04Department: NIH department code

      Mechanisms underlying hepatic immune cell recruitment in nonalcoholic fatty liver disease
      $406,609

      award amount

    Also a principal investigator on 5R01DK130949-04, led by Michael Oertel.

29. Yael Nechemia-Arbely

    Leads 1 award · $397,500

    • 5R35GM142717-04Department: NIH department code

      Mechanisms of epigenetic assembly, maintenance and propagation of human centromeres
      $397,500

      award amount

30. Christian Antonio Fernandez

    Leads 1 award · $396,750

    • 1R01DK140079-01Department: NIH department code

      Mechanistic Study of PEG-asparaginase-Induced Liver Injury
      $396,750

      award amount

31. Jonathan M Beckel

    Leads 1 award · $381,600

    • 5R01DK136505-02Department: NIH department code

      Characterization of Hypogastric Afferent Pathway Involved in Urinary Bladder Function and Dysfunction
      $381,600

      award amount

32. Simone Brixius-Anderko

    Leads 1 award · $376,787

    • 1R35GM155319-01Department: NIH department code

      STUDIES ON FATTY ACID METABOLIZING CYTOCHROME P450 ENZYMES
      $376,787

      award amount

33. Elise Fouquerel

    Leads 1 award · $374,355

    • 5R35GM142982-05Department: NIH department code

      Mechanistic insight into oxidative stress-mediated genome instability
      $374,355

      award amount

34. Steffi Oesterreich

    Leads 1 award · $355,698

    • 5R01CA252378-04Department: NIH department code

      Credentialing Models of Invasive Lobular Breast Cancer for Translational Research

      Principal investigators: Steffi Oesterreich (contact PI), Adrian V Lee

      $355,698

      award amount

    Also a principal investigator on 5R01CA256161-04, led by Adrian V Lee.

35. Xiaochao Ma

    Leads 1 award · $326,710

    • 5R01DK126875-04Department: NIH department code

      The ABCG2 transporter in protoporphyrin IX disposition: from toxicity to therapy
      $326,710

      award amount

36. In-Kwon Kim

    Leads 1 award · $324,811

    • 7R01GM141226-05Department: NIH department code

      Reversal of residue-specicific ADP-ribosylations by ADP-ribosyl-acceptor hydrolases
      $324,811

      award amount

37. Tija C. Jacob

    Leads 1 award · $297,503

    • 5T32GM133332-05Department: NIH department code

      Predoctoral Training in Pharmacological Sciences (Resubmission)
      $297,503

      award amount

38. Michelle M Williams

    Leads 1 award · $249,000

    • 4R00CA266748-03Department: NIH department code

      Targeting heme metabolism to initiate an immune response against breast cancer liver metastasis
      $249,000

      award amount

39. Wei Zhang

    Leads 1 award · $249,000

    • 4R00GM141269-03Department: NIH department code

      Light triggered materials for on-demand local anesthesia and tissue adhesive dissolution
      $249,000

      award amount

40. Patrick J Pagano

    Leads 1 award · $198,750

    • 1R21AG089718-01Department: NIH department code

      NOX2 Small Molecule Inhibitors as a Therapeutic Strategy in the Treatment of Alzheimer’s Disease

      Principal investigators: Patrick J Pagano (contact PI), Alberto L Vazquez

      $198,750

      award amount

41. Robert Parise

    Leads 1 award · $184,933

    • 5R50CA211241-09Department: NIH department code

      Cancer Pharmacokinetics Research Specialist
      $184,933

      award amount

42. Kerry McGarr Empey

    Leads 1 award · $177,591

    • 5R21AI171241-02Department: NIH department code

      Optimization of a Self-Adjuvanting Particle System for Delivering Respiratory Syncytial Virus Prefusion Protein

      Principal investigators: Kerry McGarr Empey (contact PI), Wilson S Meng

      $177,591

      award amount

43. Viet Hoang Man

    Leads 1 award · $147,285

    • 5K25AG070277-04Department: NIH department code

      Development of novel computational protocols to study amyloid oligomerization
      $147,285

      award amount

44. Anne Wondisford

    Leads 1 award · $53,974

    • 5F30CA278287-02Department: NIH department code

      Understanding the impact of DNA ADP-ribosylation on telomere function in cancer cells
      $53,974

      award amount

45. Jie Bin Liu

    Leads 1 award · $53,974

    • 5F30CA278319-02Department: NIH department code

      Characterizing and Targeting ERBB2 Mutations in Invasive Lobular Carcinoma
      $53,974

      award amount

46. Christian J Goossen

    Leads 1 award · $48,974

    • 1F31HL167563-01A1Department: NIH department code

      Endothelial NOX1-Mediated AMPKa1 Propagates Hypoxia-Induced Pulmonary Hypertension via the CIP/KIP family of CDK inhibitors
      $48,974

      award amount

47. Nicole Colussi

    Leads 1 award · $48,974

    • 1F31HL172595-01Department: NIH department code

      Bridging the gap of endogenous nitro-conjugated linoleic acid formation and signaling
      $48,974

      award amount

48. Robert Hall

    Leads 1 award · $48,974

    • 1F31HL172522-01Department: NIH department code

      Discerning the mechanisms of CYB5R1 regulation of ferroptosis in endothelial cells
      $48,974

      award amount

49. Sofya Savransky

    Leads 1 award · $48,974

    • 1F31DK136222-01A1Department: NIH department code

      The role of cell surface glycosaminoglycans (GAGs) in PTHrP bias signaling
      $48,974

      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.

• Andreas Vogt

  Co-investigator on 5R01HD104346-04, led by Michael John Palladino; 5R01HD105311-04, led by Michael John Palladino

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Nathaniel W. Snyder

  Co-investigator on 5R01CA259111-04, led by Katherine Marie Aird; 3R01CA259111-04S1, led by Katherine Marie Aird

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Mo Reza Ebrahimkhani

  Co-investigator on 1R01DK140405-01, led by Michael Oertel

  From the FY2024 awards this person leads

  • University of Pittsburgh · Pathology (NIH department code, 1 award)

• Ivet Bahar

  Co-investigator on 5R01DK116780-06, led by Jean-Pierre Vilardaga

  From the FY2024 awards this person leads

  • Stony Brook University · Biochemistry (NIH department code, 1 award)

• Dandan Sun

  Co-investigator on 5R01NS129613-02, led by Adam Carl Straub

  From the FY2024 awards this person leads

  • University of Pittsburgh · Neurology (NIH department code, 2 awards)

• Katherine C Wood

  Co-investigator on 5R01NS129613-02, led by Adam Carl Straub

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Amaia Lujambio

  Co-investigator on 5R01CA251155-05, led by Satdarshan Singh Monga

  From the FY2024 awards this person leads

  • Icahn School of Medicine at Mount Sinai · Internal Medicine (NIH department code, 1 award)

• A Paula Monaghan-Nichols

  Co-investigator on 5R01HD104215-04, led by Donald B Defranco

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Venkatesh Sampath

  Co-investigator on 5R01HD104215-04, led by Donald B Defranco

  From the FY2024 awards this person leads

  • Children'S Mercy Hosp (Kansas City, Mo) (no department on record, 2 awards)

• Azra Bihorac

  Co-investigator on 5R01DK121730-04, led by Sandra L Kane-Gill

  From the FY2024 awards this person leads

  • University of Florida · Internal Medicine (NIH department code, 3 awards)

• Eric Eugene Kelley

  Co-investigator on 5R01HL153532-04, led by Adam Carl Straub

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Timothy W Synold

  Co-investigator on 5U24CA247643-05, led by Jan Hendrik Beumer

  From the FY2024 awards this person leads

  • Beckman Research Institute/City of Hope (no department on record, 2 awards)

• Sua Myong

  Co-investigator on 5R01CA207342-07, led by Patricia L Opresko

  From the FY2024 awards this person leads

  • Boston Children's Hospital · Neurosciences (topic-inferred, 1 award)
  • Boston Children's Hospital · Genetics (topic-inferred, 1 award)
  • Boston Children's Hospital (no department on record, 1 award)

• Wei Yang

  Co-investigator on 5R01GM147673-03, led by Junmei Wang

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Andrew W Duncan

  Co-investigator on 5T32EB001026-20, led by Satdarshan Singh Monga

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Alberto L Vazquez

  Co-investigator on 1R21AG089718-01, led by Patrick J Pagano

  From the FY2024 awards this person leads

  • University of Pittsburgh · Radiology (NIH department code, 1 award)

• Wilson S Meng

  Co-investigator on 5R21AI171241-02, led by Kerry McGarr Empey

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.