Pharmacology at University of Pittsburgh

Leads a grant in this department

46 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Defranco, Donald B

   Leads 3 awards · $1,311,758

   • 1R01HD104215-01A1Department: NIH department code

     A Safer Glucocorticoid to Treat Neonatal Lung Injury with Limited Adverse Neurologic Effects
     $606,797

     award amount
   • 5R01HD087288-05Department: NIH department code

     Selective Glucocorticoid Action in the Developing Brain
     $509,336

     award amount
   • 5R21HD097694-02Department: NIH department code

     A Novel Glucocorticoid with Limited Adverse Effects in Neonatal Brain
     $195,625

     award amount

2. Palladino, Michael John

   Leads 3 awards · $1,279,756

   • 1R01HD104346-01A1Department: NIH department code

     High-content screening for TPI Deficiency therapeutics
     $578,477

     award amount
   • 1R01HD105311-01Department: NIH department code

     Developing the first TPI Df therapeutics
     $543,529

     award amount
   • 1R03NS119664-01A1Department: NIH department code

     Developing a murine TPI Df model
     $157,750

     award amount

3. Xie, Wen

   Leads 2 awards · $1,227,764

   • 5R35ES030429-03Department: NIH department code

     Xenobiotic Receptors in Mediating the Environmental Effects on Human Disease and Morbidity
     $875,639

     award amount
   • 5R01DK117370-03Department: NIH department code

     PXR-Mediated Xenobiotic Response in the Pathog enesis Hemorrhagic Shock
     $352,125

     award amount

4. Lee, Adrian V

   Leads 2 awards · $1,159,948

   • 1R01CA256161-01A1Department: NIH department code

     Estrogen receptor fusions genes as drivers of endocrine resistance in breast cancer
     $586,301

     award amount
   • 1S10OD028483-01A1Department: NIH department code

     High-Throughput Computing for Genomics and Bioinformatics Research
     $573,647

     award amount

5. Singh, Shivendra

   Leads 3 awards · $1,057,672

   • 5R01CA225716-03Department: NIH department code

     Biomarkers of Sulforaphane/Broccoli Sprout Extract in Prostate Cancer
     $480,187

     award amount
   • 5R01CA219180-03Department: NIH department code

     The Role of FoxQ1 in Breast Cancer Chemoprevention by Allium Constituents - R01CA219180
     $357,994

     award amount
   • 3R01CA225716-03S1Department: NIH department code

     Biomarkers of Sulforaphane/Broccoli Sprout Extract in Prostate Cancer
     $219,491

     award amount

6. Ma, Xiaochao

   Leads 3 awards · $948,192

   • 5R01AI131983-05Department: NIH department code

     Pharmacoenhancers for antiretroviral therapy: safety and future development
     $382,103

     award amount
   • 1R01DK126875-01A1Department: NIH department code

     The ABCG2 transporter in protoporphyrin IX disposition: from toxicity to therapy
     $335,995

     award amount
   • 5R21AT011088-02Department: NIH department code

     Preclinical screening and validation for PXR-mediated herb-drug interactions associated with anti-HIV therapy
     $230,094

     award amount

7. Aird, Katherine Marie

   Leads 2 awards · $926,583

   • 1R01CA259111-01Department: NIH department code

     Metabolic and epigenetic reprogramming in cyclin E high ovarian cancer
     $574,305

     award amount
   • 7R37CA240625-02Department: NIH department code

     Investigating p16 Loss in Pro-tumorigenic Metabolism
     $352,278

     award amount

8. Van Houten, Bennett

   Leads 1 award · $906,257

   • 5R35ES031638-02Department: NIH department code

     Watching cooperative interactions between base and nucleotide excision repair proteins
     $906,257

     award amount

9. Zhang, Lin

   Leads 2 awards · $826,747

   • 5R01CA236271-03Department: NIH department code

     Role of necroptosis in colorectal cancer therapy
     $445,723

     award amount
   • 1R01CA248112-01A1Department: NIH department code

     BET degraders for improving colorectal cancer therapy
     $381,024

     award amount

10. Li, Song

    Leads 2 awards · $811,593

    • 5R01CA219399-05Department: NIH department code

      Immunostimulatory Nanocarrier for Breast Cancer Immunochemotherapy
      $454,633

      award amount
    • 5R01CA223788-04Department: NIH department code

      Nanotherapeutics for Synergistic Targeting of Myc in Prostate Cancer
      $356,960

      award amount

11. Oesterreich, Steffi

    Leads 2 awards · $748,397

    • 5R01CA221303-04Department: NIH department code

      Mechanism-based strategies to target ER-mutant endocrine resistant breast cancer
      $393,861

      award amount
    • 5R01CA224909-04Department: NIH department code

      FGFR4: A druggable mediator of endocrine resistance in breast cancer
      $354,536

      award amount

12. Schopfer, Francisco Jose

    Leads 2 awards · $746,298

    • 5R01DK112854-04Department: NIH department code

      Predominant protective role in hepatic steatosis and obesity by fish oil-derived furans
      $396,123

      award amount
    • 5R01GM125944-04Department: NIH department code

      Formation, absorption, distribution, storage and protein targets to define activity of pleiotropic endogenous nitrated fatty acids
      $350,175

      award amount

13. Yang, Da

    Leads 2 awards · $715,988

    • 1R01CA255196-01Department: NIH department code

      A novel lncRNA-responsive and xenobiotic receptor-mediated regulation of drug metabolism and disposition
      $357,994

      award amount
    • 5R01CA222274-04Department: NIH department code

      The oncogenic role of EPIC1MYC axis in breast cancer
      $357,994

      award amount

14. Xie, Xiang-Qun

    Leads 1 award · $623,964

    • 1R01DA052329-01A1Department: NIH department code

      Cannabinoid CB2 Receptor Structure and Allosteric Modulators
      $623,964

      award amount

15. Pagano, Patrick J

    Leads 1 award · $577,109

    • 5R01HL142248-03Department: NIH department code

      Progressive degenerative role of Nox and thrombospondin-1 in the aging vasculature
      $577,109

      award amount

16. Lee, Adrian V

    Leads 1 award · $573,041

    • 1R01CA252378-01A1Department: NIH department code

      Credentialing Models of Invasive Lobular Breast Cancer for Translational Research
      $573,041

      award amount

17. Bihorac, Azra

    Leads 1 award · $562,198

    • 1R01DK121730-01A1Department: NIH department code

      (MEnD-AKI) Multicenter Implementation of an Electronic Decision Support System for Drug-associated AKI
      $562,198

      award amount

18. Zhang, Cheng

    Leads 2 awards · $547,750

    • 5R35GM128641-04Department: NIH department code

      Structure, pharmacology and signaling of G protein-coupled receptors (GPCRs) in inflammation
      $391,250

      award amount
    • 1R03TR003306-01A1Department: NIH department code

      Structure and pharmacology of GPR32 in the resolution of inflammation
      $156,500

      award amount

19. Levitan, Edwin S

    Leads 1 award · $540,865

    • 5R01NS032385-25Department: NIH department code

      Dense-Core Vesicle Circulation, Capture and Synaptic Neuropeptide Release
      $540,865

      award amount

20. Beumer, Jan Hendrik

    Leads 1 award · $522,551

    • 5U24CA247643-02Department: NIH department code

      PITT-CAL ETCTN PK Resource Laboratory
      $522,551

      award amount

21. Johnston, Paul A.

    Leads 1 award · $512,558

    • 5R01CA229836-03Department: NIH department code

      qHTS of Patient Derived HCC Models to Identify Novel Probes/Therapeutic Agents
      $512,558

      award amount

22. Jackson, Edwin Kerry

    Leads 1 award · $501,758

    • 5R01HL109002-10Department: NIH department code

      The 8-Aminopurine Hypothesis
      $501,758

      award amount

23. Yu, Jian

    Leads 1 award · $443,378

    • 5R01CA247231-02Department: NIH department code

      Targeting defective necroptosis in colorectal cancer
      $443,378

      award amount

24. Sant, Shilpa

    Leads 1 award · $434,007

    • 5R37CA232209-04Department: NIH department code

      Three-dimensional organoid models to study breast cancer progression
      $434,007

      award amount

25. Vilardaga, Jean-Pierre

    Leads 1 award · $429,297

    • 5R01DK116780-04Department: NIH department code

      Structural Basis of PTH Receptor Function
      $429,297

      award amount

26. Frahm, Krystle Anne

    Leads 3 awards · $396,850

    • 5R21DK121266-03Department: NIH department code

      The Role of a Novel Obesity-Risk Variant on Hypothalamic Regulation of Energy Homeostasis
      $195,625

      award amount
    • 5K01DK115543-05Department: NIH department code

      Impact of CREBRF and its obesity-risk variant on hypothalamic glucocorticoid and neuroendocrine output using molecular, cellular, and physiological approaches.
      $148,403

      award amount
    • 3K01DK115543-04S1Department: NIH department code

      Impact of CREBRF and its obesity-risk variant on hypothalamic glucocorticoid and neuroendocrine output using molecular, cellular, and physiological approaches.
      $52,822

      award amount

27. Huryn, Donna M

    Leads 1 award · $395,006

    • 4R33NS107785-03Department: NIH department code

      20-HETE Formation Inhibitors in Cardiac Arrest
      $395,006

      award amount

28. Altschuler, Daniel L

    Leads 1 award · $391,250

    • 5R01GM130612-03Department: NIH department code

      Role of soluble adenylyl cyclase in TSH biology
      $391,250

      award amount

29. Jacob, Tija C.

    Leads 1 award · $391,250

    • 5R01MH114908-03Department: NIH department code

      Benzodiazepine treatment induced neuroplasticity
      $391,250

      award amount

30. Nechemia-Arbely, Yael

    Leads 1 award · $391,250

    • 1R35GM142717-01Department: NIH department code

      Mechanisms of epigenetic assembly, maintenance and propagation of human centromeres
      $391,250

      award amount

31. Bernstein, Kara A

    Leads 2 awards · $390,102

    • 5R01ES030335-03Department: NIH department code

      Replication fork dynamics and repair by Rad51 paralogs after DNA alkylation
      $372,608

      award amount
    • 3R01ES030335-02S1Department: NIH department code

      Replication fork dynamics and repair by Rad51 paralogs after DNA alkylation
      $17,494

      award amount

32. Wang, Qiming Jane

    Leads 1 award · $358,483

    • 5R01CA229431-03Department: NIH department code

      A novel mitotic regulatory axis in neuroendocrine prostate cancer
      $358,483

      award amount

33. Hu, Jing

    Leads 1 award · $357,994

    • 5R01CA236965-02Department: NIH department code

      Targeting PYK2 for the treatment of PDAC
      $357,994

      award amount

34. Huang, Yi

    Leads 1 award · $357,994

    • 1R01CA260357-01A1Department: NIH department code

      Role of LSD1 in Triple Negative Breast Cancer Development and Therapeutic Response
      $357,994

      award amount

35. Beckel, Jonathan M

    Leads 1 award · $352,125

    • 5R01DK117884-04Department: NIH department code

      Underlying mechanisms controlling urothelial ATP release and their contributions to urinary bladder physiology and pathophysiology
      $352,125

      award amount

36. Kelley, Eric Eugene

    Leads 1 award · $337,544

    • 5R01DK124510-02Department: NIH department code

      Targeting Uric Acid as a Therapeutic for NASH
      $337,544

      award amount

37. Fernandez, Christian Antonio

    Leads 1 award · $322,194

    • 5R01CA216815-05Department: NIH department code

      Improving the disposition of antileukemic asparaginase after drug-induced immunotoxicity
      $322,194

      award amount

38. Galbiati, Ferruccio

    Leads 1 award · $313,000

    • 5R01CA205165-05Department: NIH department code

      Mechanisms that control the progression from premalignant lesions to adenocarcinomas in the lung
      $313,000

      award amount

39. Jiang, Yu

    Leads 1 award · $313,000

    • 5R01GM132127-03Department: NIH department code

      Mechanisms of Signaling Protein Retention in the Primary Cilium
      $313,000

      award amount

40. Jacob, Tija C.

    Leads 1 award · $292,577

    • 5T32GM133332-02Department: NIH department code

      Predoctoral Training in Pharmacological Sciences (Resubmission)
      $292,577

      award amount

41. Fouquerel, Elise

    Leads 1 award · $261,773

    • 7R35GM142982-02Department: NIH department code

      Mechanistic insight into oxidative stress-mediated genome instability
      $261,773

      award amount

42. Sun, Jingjing

    Leads 1 award · $218,699

    • 1R21CA249649-01A1Department: NIH department code

      Tumor-permeable nanoparticles for enhanced pancreatic cancer immunochemotherapy
      $218,699

      award amount

43. Parise, Robert

    Leads 1 award · $182,510

    • 2R50CA211241-06Department: NIH department code

      Cancer Pharmacokinetics Research Specialist
      $182,510

      award amount

44. Man, Viet Hoang

    Leads 1 award · $147,268

    • 1K25AG070277-01A1Department: NIH department code

      Development of novel computational protocols to study amyloid oligomerization
      $147,268

      award amount

45. Vitturi, Dario A

    Leads 2 awards · $122,652

    • 1R03HL157878-01Department: NIH department code

      Anti-inflammatory actions of a novel hemin-induced electrophile in Sickle Cell Disease
      $78,250

      award amount
    • 3K01HL133331-05S1Department: NIH department code

      Protection against sickle cell disease nephropathy by nitrated fatty acids
      $44,402

      award amount

46. Kaminski, Nicole

    Leads 1 award · $46,036

    • 1F31CA264885-01Department: NIH department code

      A novel role for RAD51AP1 in regulation of TERRA lincRNA during ALT-mediated telomere extension
      $46,036

      award amount