Biochemistry at UT Health Science Center Houston

Leads a grant in this department

41 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Patrick Sung

   Leads 4 awards · $1,830,338

   • 5R35CA241801-06Department: NIH department code

     Mechanisms of DNA Homology-directed Genome Repair and Tumor Suppression
     $834,337

     award amount
   • 5R01ES007061-30Department: NIH department code

     Mechanisms of DNA Double-strand Break End Resection and Repair Pathway Choice
     $505,540

     award amount
   • 5R01CA168635-13Department: NIH department code

     Mechanistic Dissection of the BRCA1-SETX-dependent Pathway of R-loop Avoidance and Genome Maintenance

     Principal investigators: Patrick Sung (contact PI), Gary M Kupfer

     $470,303

     award amount
   • 3R01ES007061-30S1Department: NIH department code

     MECHANISMS OF DNA DOUBLE-STRAND BREAK END RESECTION AND REPAIR PATHWAY CHOICE..
     $20,158

     award amount

2. Wenbo Li

   Leads 3 awards · $1,721,146

   • 5R01AG082132-02Department: NIH department code

     Enhancer RNAs in brain gene regulation and Alzheimer's disease
     $739,201

     award amount
   • 5U01HL156059-05Department: NIH department code

     Beyond Gene Dosage: Understanding Down Syndrome via 4D Genome Organization
     $624,204

     award amount
   • 5R01GM136922-05Department: NIH department code

     Mechanisms Underlying Enhancer Rnp Mediated Gene Regulation And Genome Organization
     $357,741

     award amount

3. Shaun Olsen

   Leads 3 awards · $1,560,407

   • 1R01CA293655-01Department: NIH department code

     Structure and function of RAD51 paralog tumor suppressor complexes in genome maintenance

     Principal investigators: Shaun Olsen (contact PI), Eric C Greene, Yashpal Rawal

     $669,325

     award amount
   • 1S10OD036251-01Department: NIH department code

     A high performance computing cluster to support structural biology
     $571,780

     award amount
   • 5R01GM128731-07Department: NIH department code

     Structure and Function of the Essential Cell Cycle Regulator Cdc34
     $319,302

     award amount

4. Irina I Serysheva

   Leads 4 awards · $1,226,033

   • 1R35GM153178-01Department: NIH department code

     Mechanisms of inositol trisphosphate receptor-mediated calcium signaling
     $515,736

     award amount
   • 1R21NS138590-01Department: NIH department code

     Structural basis of ER-mitochondria membrane contacts and neuronal health
     $429,000

     award amount
   • 5R21AR082833-02Department: NIH department code

     Defining architecture of EC coupling machinery in situ
     $166,452

     award amount
   • 3R35GM153178-01S1Department: NIH department code

     Administrative Supplement: Mechanisms of inositol trisphosphate receptor-mediated calcium signaling
     $114,845

     award amount

5. Seung-Hee Yoo

   Leads 3 awards · $1,137,186

   • 1R01NS136677-01Department: NIH department code

     Regulation of headache pain responses by the Trigeminal ganglion clock

     Principal investigators: Seung-Hee Yoo (contact PI), Mark J Burish

     $499,303

     award amount
   • 5R35GM145232-03Department: NIH department code

     Mammalian circadian rhythms: from genes to mechanisms
     $387,883

     award amount
   • 3R35GM145232-03S1Department: NIH department code

     Mammalian circadian rhythms: from genes to mechanisms
     $250,000

     award amount

6. Julio Francisco Cordero-Morales

   Leads 2 awards · $857,041

   • 7R01NS131184-02Department: NIH department code

     The Role of Sensory Receptors in Angelman Syndrome

     Principal investigators: Julio Francisco Cordero-Morales (contact PI), Valeria Vasquez

     $467,041

     award amount
   • 5R35GM149218-03Department: NIH department code

     Sensory Ion Channel Modulation by Bioactive Lipids
     $390,000

     award amount

7. Philip T Loverde

   Leads 1 award · $810,158

   • 1R56AI180213-01A1Department: NIH department code

     Preclinical Testing of Potential Next-generation Antischistosomal Compounds

     Principal investigators: Philip T Loverde (contact PI), Michael Darin Cameron, Sevan Najm Alwan, Stanton Furst McHardy

     $810,158

     award amount

8. Yogesh K Gupta

   Leads 2 awards · $757,310

   • 4R01AI161363-04Department: NIH department code

     Mechanism-based Targeting of the RNA Processing Machinery of SARS-CoV-2
     $584,674

     award amount
   • 3R01AI161363-03S1Department: NIH department code

     Mechanism-based targeting of the RNA processing machinery of SARS-CoV-2-
     $172,636

     award amount

9. Vasanthi Jayaraman

   Leads 1 award · $677,822

   • 5R35GM122528-08Department: NIH department code

     Dynamics Of Ligand Gated Ion Channels
     $677,822

     award amount

10. John Lee Spudich

    Leads 1 award · $627,370

    • 5R35GM140838-04Department: NIH department code

      Structure/Function of Channelrhodopsins and Related Retinylidene Proteins
      $627,370

      award amount

11. Kevin B Koronowski

    Leads 2 awards · $607,103

    • 5R35GM150618-02Department: NIH department code

      Fundamental Mechanisms of Higher-Order Circadian Rhythms
      $387,500

      award amount
    • 3R35GM150618-01S1Department: NIH department code

      Fundamental Mechanisms of Higher-Order Circadian Rhythms
      $219,603

      award amount

12. Harry Karmouty-Quintana

    Leads 2 awards · $594,411

    • 5R01HL157100-04Department: NIH department code

      Sineoculis Homeobox Homolog 1 (Six1) in Pulmonary Fibrosis
      $505,741

      award amount
    • 3R01HL157100-04S1Department: NIH department code

      Sineoculis Homeobox Homolog 1 (Six1) in Pulmonary Fibrosis
      $88,670

      award amount

13. Dmitri N Ivanov

    Leads 1 award · $570,845

    • 2R37AI136697-05Department: NIH department code

      Biochemistry of SAMHD1-mediated innate immunity responses
      $570,845

      award amount

14. Tingting Weng Mills

    Leads 1 award · $548,532

    • 1R01HL168128-01A1Department: NIH department code

      Macrophage NUDT21-mediated alternative polyadenylation in lung injury
      $548,532

      award amount

15. Zheng Chen

    Leads 1 award · $507,325

    • 1R01AG089967-01Department: NIH department code

      Circadian regulation of mitochondrial function by muscle RORs to promote healthy aging
      $507,325

      award amount

16. Peng Zhao

    Leads 1 award · $501,032

    • 5R01DK133304-03Department: NIH department code

      A novel pathway controls liver injury in NASH
      $501,032

      award amount

17. Reuben S Harris

    Leads 1 award · $460,050

    • 5R37AI064046-20Department: NIH department code

      APOBEC3 Proteins in HIV Restriction
      $460,050

      award amount

18. Anna L Malkova

    Leads 1 award · $458,325

    • 7R35GM127006-07Department: NIH department code

      Double strand break repair maelstrom: causes, mechanisms and genome destabilizing consequences
      $458,325

      award amount

19. William Dowhan

    Leads 1 award · $455,548

    • 5R01GM121493-07Department: NIH department code

      Dynamic Lipid and Protein Organization in Cell Membranes

      Principal investigators: William Dowhan (contact PI), Mikhail V. Bogdanov

      $455,548

      award amount

20. Xiaotian Zhang

    Leads 1 award · $446,729

    • 5R01HL170115-02Department: NIH department code

      The dissection of non-canonical cis-regulatory elements downstream of beta-globin locus in the fetal hemoglobin gene regulation
      $446,729

      award amount

21. Jean X Jiang

    Leads 1 award · $433,022

    • 5R01EY012085-26Department: NIH department code

      Intercellular Communication in the Eye Lens
      $433,022

      award amount

22. Bruce J Nicholson

    Leads 1 award · $429,046

    • 5R01HD109027-04Department: NIH department code

      Molecular mechanisms of gap junction promotion of lesion formation in Endometriosis
      $429,046

      award amount

23. Kyoji Tsuchikama

    Leads 1 award · $390,000

    • 5R35GM138264-05Department: NIH department code

      Chemical approaches for generating blood-brain barrier-permeable antibody conjugates
      $390,000

      award amount

24. Valeria Vasquez

    Leads 1 award · $386,961

    • 1R35GM153208-01Department: NIH department code

      Mechanosensitive Ion Channels Modulation by Membrane Composition
      $386,961

      award amount

    Also a principal investigator on 7R01NS131184-02, led by Julio Francisco Cordero-Morales.

25. Nami McCarty

    Leads 1 award · $351,975

    • 5R01CA181319-09Department: NIH department code

      Analyzing protein homeostasis pathways in multiple myeloma stem-like cells
      $351,975

      award amount

26. Weixing Wilson Zhao

    Leads 2 awards · $347,616

    • 5R01GM141091-04Department: NIH department code

      Genome Maintenance via the BRCA-RAD54 Axis
      $325,500

      award amount
    • 3R01GM141091-04S1Department: NIH department code

      Genome Maintenance via the BRCA-RAD54 Axis
      $22,116

      award amount

27. Kuang-Lei Tsai

    Leads 1 award · $337,116

    • 5R01GM143587-04Department: NIH department code

      Structural insights into the Argonaute-containing CDK8 complex
      $337,116

      award amount

28. Elizabeth Victorina Wasmuth

    Leads 3 awards · $336,936

    • 5R00GM140264-05Department: NIH department code

      Biochemical, structural and molecular dissection of androgen receptor transcriptional activity
      $248,999

      award amount
    • 3R00GM140264-05S1Department: NIH department code

      Biochemical, structural and molecular dissection of androgen receptor transcriptional activity
      $75,375

      award amount
    • 3R00GM140264-04S1Department: NIH department code

      Biochemical, structural and molecular dissection of androgen receptor transcriptional activity.
      $12,562

      award amount

29. Yuzuru Shiio

    Leads 1 award · $336,835

    • 5U01CA283414-02Department: NIH department code

      The role of the receptor complex and the cofactors in IGSF10 signaling
      $336,835

      award amount

30. David Steven Libich

    Leads 1 award · $325,500

    • 5R01GM140127-04Department: NIH department code

      An Integrated Biochemical and Structural Approach to Delineating the Biology of EWSR1
      $325,500

      award amount

31. Lei Zheng

    Leads 1 award · $319,800

    • 5R01GM143418-04Department: NIH department code

      Structure and function of a metabolic pacemaker in bacterial cell membrane
      $319,800

      award amount

32. Lu Wang

    Leads 1 award · $248,853

    • 5R00AG065500-04Department: NIH department code

      Mechanisms of enhancer regulation in aging and age-related diseases
      $248,853

      award amount

33. Eloise Dray

    Leads 1 award · $232,500

    • 1R21ES035997-01Department: NIH department code

      Understanding post translational modifiers in DNA damage repair
      $232,500

      award amount

34. Bernard Fongang

    Leads 1 award · $220,142

    • 5K01NS126489-02Department: NIH department code

      Delineating the role of the gut microbiota and its derived metabolites in the development of dementia in multi-ethnic populations
      $220,142

      award amount

35. Dongwen Lyu

    Leads 1 award · $192,844

    • 1R21CA286307-01Department: NIH department code

      Development of Caspase Cleavage Targeting Chimeras (CACTACs) for Targeted Protein Cleavage
      $192,844

      award amount

36. Youngho Kwon

    Leads 1 award · $164,435

    • 5R50CA265315-03Department: NIH department code

      BRCA-dependent Mechanisms of Genome Maintenance and Repair
      $164,435

      award amount

37. Francisca Maria Acosta

    Leads 1 award · $79,456

    • 5F32DK134051-02Department: NIH department code

      Osteocytic Connexin 43 Hemichannel Regulation of Adiposity
      $79,456

      award amount

38. Francisco Neal

    Leads 1 award · $45,318

    • 5F30CA260908-04Department: NIH department code

      Investigating contributions of BRCA2 DNA-binding domains toward maintaining genome integrity
      $45,318

      award amount

39. Erich Sohn

    Leads 1 award · $38,363

    • 1F31CA295030-01Department: NIH department code

      Structural and mechanistic investigation into EWS::FLI1 disruption of EWS function in transcription and DNA repair
      $38,363

      award amount

40. Cuauhtemoc Ulises Gonzalez

    Leads 1 award · $37,961

    • 5F99NS130928-02Department: NIH department code

      Synaptic Organization and Modulation of Kainate Receptors: Investigating the Structure, Dynamics, and Function in the Context of Trans-Synaptic Junctions
      $37,961

      award amount

41. Ashley A Auerbach

    Leads 1 award · $33,790

    • 1F31AI181573-01Department: NIH department code

      Identifying a Critical Gatekeeper for DNA Virus Restriction
      $33,790

      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.

• Michael Darin Cameron

  Co-investigator on 1R56AI180213-01A1, led by Philip T Loverde

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Sevan Najm Alwan

  Co-investigator on 1R56AI180213-01A1, led by Philip T Loverde

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Stanton Furst McHardy

  Co-investigator on 1R56AI180213-01A1, led by Philip T Loverde

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Eric C Greene

  Co-investigator on 1R01CA293655-01, led by Shaun Olsen

  From the FY2024 awards this person leads

  • Columbia University · Biochemistry (NIH department code, 3 awards)

• Yashpal Rawal

  Co-investigator on 1R01CA293655-01, led by Shaun Olsen

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Mark J Burish

  Co-investigator on 1R01NS136677-01, led by Seung-Hee Yoo

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Gary M Kupfer

  Co-investigator on 5R01CA168635-13, led by Patrick Sung

  From the FY2024 awards this person leads

  • Georgetown University (no department on record, 1 award)

• Mikhail V. Bogdanov

  Co-investigator on 5R01GM121493-07, led by William Dowhan

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.