Internal Medicine at UT Health Science Center Houston

Leads a grant in this department

50 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Robert A Clark

   Leads 1 award · $5,584,747

   • 5UM1TR004538-02Department: NIH department code

     Institute for Integration of Medicine & Science: A Partnership to Improve Health

     Principal investigators: Robert A Clark (contact PI), Amelie G Ramirez, Jennifer Sharpe Potter, Kenneth M Hargreaves

     $5,584,747

     award amount

2. Faraz Bishehsari

   Leads 3 awards · $1,590,268

   • 7R01CA279487-03Department: NIH department code

     Development of a precision medicine platform for circadian based therapeutics in pancreatic cancer
     $798,207

     award amount
   • 1U01AG086145-01Department: NIH department code

     Impact of Circadian-Microbiome Interaction on the Gut-Pancreas Axis in Aging
     $671,922

     award amount
   • 7R21CA277110-03Department: NIH department code

     Personalized Organoid-Chip Model For Drug Testing in Pancreatic Cancer
     $120,139

     award amount

3. Eric J Thomas

   Leads 2 awards · $1,449,345

   • 5R18HS029362-03Department: NIH department code

     Safety II Together: Coupling teaming science with patient engagement and health information transparency to coproduce diagnostic excellence

     Principal investigators: Eric J Thomas (contact PI), Sigall Bell

     $999,346

     award amount
   • 5R18HS028779-03Department: NIH department code

     A New Combination of Evidence Based Interventions to Improve Primary Care Diagnostic Safety and Efficiency: a Stepped Wedge Cluster RCT
     $449,999

     award amount

4. Shangang Zhao

   Leads 3 awards · $1,306,458

   • 1R01AG084646-01A1Department: NIH department code

     Effects of leptin modulation on health span and lifespan
     $669,958

     award amount
   • 1R01DK138035-01Department: NIH department code

     Paracrine effects of leptin in regulating visceral fat expansion
     $387,500

     award amount
   • 5R00AG068239-04Department: NIH department code

     Impact of a Novel Secreted Enzyme J18 on Healthspan and Lifespan
     $249,000

     award amount

5. Ralph A Defronzo

   Leads 3 awards · $1,294,599

   • 5R01DK024092-39Department: NIH department code

     SGLT2 Inhibitors, Ketogenesis, and Ketoacidosis
     $647,274

     award amount
   • 5R01DK107680-08Department: NIH department code

     Ketones, Muscle Metabolism, and SGLT2 Inhibitors
     $621,441

     award amount
   • 3R01DK107680-08S1Department: NIH department code

     Ketones, Muscle Metabolism, and SGLT2 Inhibitors
     $25,884

     award amount

   Also a principal investigator on 5R01DK129676-03, led by Luke Norton.

6. Xianlin Han

   Leads 2 awards · $1,264,251

   • 4R01AG061729-02Department: NIH department code

     Sulfatide deficiency: A novel mechanism leading to reactive astrogliosis in aging and Alzheimer’s disease
     $635,549

     award amount
   • 1R01AG085545-01Department: NIH department code

     The role of sulfatide in the development of tauopathy in the context of ADRD

     Principal investigators: Xianlin Han (contact PI), Jeffrey L. Dupree, Lizhen Chen

     $628,702

     award amount

7. Madesh Muniswamy

   Leads 3 awards · $1,252,729

   • 5R01DK135179-02Department: NIH department code

     Mechanisms and therapeutic potential of blocking the mitochondrial Mg2+ channel Mrs2 in obesity and NAFLD

     Principal investigators: Madesh Muniswamy (contact PI), Joseph A. Baur

     $503,933

     award amount
   • 5R35GM145294-03Department: NIH department code

     Magnesium flux compendium: Discover ligands, channels, and metabolic signals
     $498,983

     award amount
   • 3R35GM145294-03S1Department: NIH department code

     Magnesium flux compendium: Discover ligands, channels, and metabolic signals
     $249,813

     award amount

8. Simon Andrew Gayther

   Leads 2 awards · $1,213,323

   • 7R01CA244569-05Department: NIH department code

     Characterizing non-coding somatic and germline variant interactions in ovarian cancer

     Principal investigators: Simon Andrew Gayther (contact PI), Alexander Gusev

     $614,121

     award amount
   • 7R01CA259058-03Department: NIH department code

     Common biology underlying pleiotropic breast, prostate and ovarian cancer risk loci

     Principal investigators: Simon Andrew Gayther (contact PI), Matthew L Freedman, Siddhartha Kar

     $599,202

     award amount

9. Joel Tsevat

   Leads 2 awards · $1,205,642

   • 5K12TR004529-02Department: NIH department code

     CTSA K12 Program at The University of Texas Health Science Center at San Antonio

     Principal investigators: Joel Tsevat (contact PI), Alison G Cahill

     $956,666

     award amount
   • 3K12TR004529-02S1Department: NIH department code

     CTSA K12 Program at The University of Texas Health Science Center at San Antonio

     Principal investigators: Joel Tsevat (contact PI), Alison G Cahill

     $248,976

     award amount

10. Sunil K Ahuja

    Leads 1 award · $1,183,478

    • 5U01AI158460-03Department: NIH department code

      Mechanistic clinical trial of blocking the IL-4/13 axis in asthmatics precision phenotyped in an aeroallergen challenge chamber before, during and after receipt of dupilumab
      $1,183,478

      award amount

11. Ali J Marian

    Leads 2 awards · $1,168,234

    • 5R01AG082751-02Department: NIH department code

      Cytosolic DNA is the Link Between Genomic Instability and Cardiovascular Aging
      $587,703

      award amount
    • 2R01HL132401-09Department: NIH department code

      Mechanisms and Therapeutic Targeting of DNA Damage in Dilated Cardiomyopathy Caused by LMNA Mutations
      $580,531

      award amount

12. Luke Norton

    Leads 2 awards · $1,124,691

    • 5R01DK129676-03Department: NIH department code

      Targeting hepatic mitochondrial function in humans with NAFLD using insulin sensitizers

      Principal investigators: Luke Norton (contact PI), Ralph A Defronzo

      $654,870

      award amount
    • 5R01DK128247-03Department: NIH department code

      The Regulation of Hepatic Metabolic Zonation by the Diabetes Gene TCF7L2
      $469,821

      award amount

13. Eva M. Sevick

    Leads 2 awards · $1,096,875

    • 5R01CA276513-02Department: NIH department code

      Personalized, antigen-directed immunotherapy delivered to lymph nodes

      Principal investigators: Eva M. Sevick (contact PI), Mona Mohsen, Zhongming Zhao

      $548,896

      award amount
    • 5R01NS126437-03Department: NIH department code

      Assessing CSF flow dynamics in pediatric hemorrhagic hydrocephalus

      Principal investigators: Eva M. Sevick (contact PI), Banghe Zhu, Manish Narendra Shah

      $547,979

      award amount

14. Callie S Kwartler

    Leads 2 awards · $1,000,282

    • 1R01HL175148-01Department: NIH department code

      A novel nuclear role for smooth muscle alpha-actin
      $563,128

      award amount
    • 1R01AR084437-01Department: NIH department code

      Nuclear skeletal muscle alpha-actin and intranuclear rod myopathy
      $437,154

      award amount

15. Long-Jun Wu

    Leads 1 award · $851,223

    • 7R35NS132326-02Department: NIH department code

      How microglia sense and regulate neuronal activity in the adult brain
      $851,223

      award amount

16. Patricia Leal Dahia

    Leads 3 awards · $805,017

    • 5R01CA264248-04Department: NIH department code

      Addressing biological and therapeutic gaps in rare neuroendocrine cancer with a novel organoid-based model

      Principal investigators: Patricia Leal Dahia (contact PI), Alice Soragni

      $468,662

      award amount
    • 3R01CA264248-04S2Department: NIH department code

      Evaluating the impact of genetic ancestry on the biology and drug response profile of pheochromocytoma and paraganglioma-derived organoid models

      Principal investigators: Patricia Leal Dahia (contact PI), Alice Soragni

      $265,946

      award amount
    • 3R01CA264248-04S1Department: NIH department code

      Addressing biological and therapeutic gaps in rare neuroendocrine cancer with a novel organoid-based model

      Principal investigators: Patricia Leal Dahia (contact PI), Alice Soragni

      $70,409

      award amount

17. Kumar Sharma

    Leads 1 award · $790,861

    • 5U01DK114920-08Department: NIH department code

      Spatial Multi-Omics to Profile Metabolic Pathways for Kidney Disease

      Principal investigators: Kumar Sharma (contact PI), Christopher R Anderton, Theodore Alexandrov

      $790,861

      award amount

18. Kai Xu

    Leads 2 awards · $787,064

    • 7U01AI173348-02Department: NIH department code

      Structure, function, and antigenicity of emerging henipavirus surface glycoproteins
      $592,064

      award amount
    • 7UH2AI171611-02Department: NIH department code

      Targeting glycoprotein (G) domain-III for pan-lyssavirus nanobody therapeutics
      $195,000

      award amount

19. Ricardo C Aguiar

    Leads 2 awards · $697,500

    • 5R01ES031522-05Department: NIH department code

      Oxidative stress and RNA methylation
      $387,500

      award amount
    • 5R01GM140456-04Department: NIH department code

      Mitochondrial 2-hydroxyglutarate dehydrogenases modulate the cellular epitranscriptome
      $310,000

      award amount

20. Marzieh Salehi

    Leads 1 award · $690,638

    • 1R01DK140144-01Department: NIH department code

      Glycemic and Weight Loss Effects of Semaglutide in Subjects After Spinal Cord Injury and Type 2 Diabetes
      $690,638

      award amount

21. Muhammad Abdul-Ghani

    Leads 1 award · $684,914

    • 2R01DK097554-11A1Department: NIH department code

      Comparative Effectiveness of Two Initial Combination Therapies in Patients with New Onset Diabetes
      $684,914

      award amount

22. Absalon Dennis Gutierrez

    Leads 1 award · $665,637

    • 5R01DK127084-04Department: NIH department code

      Pharmacogenetics of the Response to GLP-1 in Mexican-Americans with Prediabetes
      $665,637

      award amount

23. Jordan E Lake

    Leads 1 award · $640,903

    • 5R01DK126042-05Department: NIH department code

      Metabolic impact of FGF-21 in adipose tissue and liver of PLWH
      $640,903

      award amount

24. Richard A Cox

    Leads 2 awards · $621,335

    • 7R01DK136694-02Department: NIH department code

      Leptin regulation of delta cell function
      $454,811

      award amount
    • 7R03DK135458-02Department: NIH department code

      GABP is a novel regulator of beta cell metabolism and proliferation
      $166,524

      award amount

25. Zsuzsanna Hortobagyi McMahan

    Leads 1 award · $605,667

    • 5R01AR081382-02Department: NIH department code

      Interrogating the pathophysiological mechanisms of constipation in patients with systemic sclerosis

      Principal investigators: Zsuzsanna Hortobagyi McMahan (contact PI), Jiande Chen

      $605,667

      award amount

26. Angelo Nascimbene

    Leads 1 award · $594,080

    • 5R01HL163549-02Department: NIH department code

      Von Willebrand Factor Hyperactivity, Angiogenesis and LVAD-Induced Bleeding
      $594,080

      award amount

27. Lisa Kilpela

    Leads 1 award · $563,670

    • 1R01AG086777-01Department: NIH department code

      Prospective Health Impacts of Chronic Binge Eating Disorder in Hispanic Older Women Living with Food Insecurity (PROSPERA)

      Principal investigators: Lisa Kilpela (contact PI), Carolyn Black Becker

      $563,670

      award amount

28. Dianna M Milewicz

    Leads 1 award · $542,949

    • 5T32GM150524-02Department: NIH department code

      Medical Scientist Training Program
      $542,949

      award amount

29. Ashish Kapoor

    Leads 1 award · $534,335

    • 5R01HL158901-03Department: NIH department code

      Identifying Cis-Regulatory Variants, Genes, and Regulatory Networks Underlying QT Interval Variation
      $534,335

      award amount

30. William Brian Reeves

    Leads 2 awards · $496,056

    • 5R25DK078381-18Department: NIH department code

      Promoting diversity in research careers in diabetes, digestive and kidney diseases

      Principal investigators: William Brian Reeves (contact PI), Gail L. Matters

      $378,427

      award amount
    • 2R25DK121576-06Department: NIH department code

      San Antonio Program for Undergraduate Research in Renal Science (SPURRS)
      $117,629

      award amount

31. Kimi Y Kong

    Leads 1 award · $436,807

    • 1R01CA279971-01A1Department: NIH department code

      Biomarkers For BRCA1-Deficient Cancers
      $436,807

      award amount

32. Vihang A Narkar

    Leads 1 award · $435,702

    • 5R01HL152108-04Department: NIH department code

      New therapeutic strategies for Peripheral Arterial Disease
      $435,702

      award amount

33. Kyoji Tsuchikama

    Leads 1 award · $397,082

    • 5R01CA283876-02Department: NIH department code

      Antibody-dual drug conjugates for eradicating triple-negative breast cancer with heterogeneity
      $397,082

      award amount

34. Peter A Doris

    Leads 1 award · $391,969

    • 5R01HG011252-04Department: NIH department code

      Long-read assembly and annotation of rat genomes that are important models of complex genetic disease

      Principal investigators: Peter A Doris (contact PI), Melissa Laird Smith, Theodore Kalbfleisch

      $391,969

      award amount

35. Kristin Eckel Mahan

    Leads 1 award · $390,000

    • 5R01AI158694-04Department: NIH department code

      Complement and Circadian Interactions in Inflammation and Immunity

      Principal investigators: Kristin Eckel Mahan (contact PI), Pooja Shivshankar

      $390,000

      award amount

    Also a principal investigator on 5R01DK125922-04, led by Mikhail G Kolonin.

36. Xin Ge

    Leads 1 award · $390,000

    • 5R35GM141089-04Department: NIH department code

      Therapeutic Monoclonal Antibodies Inhibiting Proteases of Biomedical Importance
      $390,000

      award amount

37. Kai Sun

    Leads 1 award · $374,400

    • 5R01DK129815-03Department: NIH department code

      Discovering the new function of DRP1 on lipid metabolism
      $374,400

      award amount

38. Mikhail G Kolonin

    Leads 1 award · $374,400

    • 5R01DK125922-04Department: NIH department code

      Metabolic consequences of adipocyte progenitor replicative senescence: mechanism and intervention

      Principal investigators: Mikhail G Kolonin (contact PI), Kristin Eckel Mahan

      $374,400

      award amount

39. Robert A Hromas

    Leads 1 award · $368,125

    • 5R01CA205224-07Department: NIH department code

      EEPD1 Repair of Stressed Replication Forks
      $368,125

      award amount

40. Wenliang Li

    Leads 1 award · $339,008

    • 5R01CA270096-03Department: NIH department code

      Dissecting and targeting a novel vulnerability in aggressive Rb1 and p53 doubly deficient prostate cancer
      $339,008

      award amount

41. Mansour M Zadeh

    Leads 1 award · $334,801

    • 5R01DK109560-10Department: NIH department code

      Bacteria-associated VB12 regulates neonatal ileal epithelium homeostasis
      $334,801

      award amount

42. Jennifer Lynne Huberty

    Leads 1 award · $324,702

    • 5R01CA262041-04Department: NIH department code

      Consumer-based meditation app, Calm, for treatment of sleep disturbance in hematological cancer patients

      Principal investigators: Jennifer Lynne Huberty (contact PI), Ruben A. Mesa

      $324,702

      award amount

43. Shervin Assassi

    Leads 1 award · $321,060

    • 5R01AR081280-02Department: NIH department code

      Interferon Regulatory Factor 7 Links Interferon Pathway Activation to the Exaggerates Fibrotic Response in Systemic Sclerosis

      Principal investigators: Shervin Assassi (contact PI), Minghua Wu

      $321,060

      award amount

44. Dana Elena Giza

    Leads 1 award · $312,000

    • 1R03AG089057-01Department: NIH department code

      Patient Priorities Survivorship Care for Older Women with Breast Cancer
      $312,000

      award amount

45. Chukwuemeka Nkemakonam Okafor

    Leads 1 award · $264,091

    • 1R34DA060078-01A1Department: NIH department code

      Development of a behavioral economic Intervention to improve HIV-related behaviors among sexual minority men.

      Principal investigators: Chukwuemeka Nkemakonam Okafor (contact PI), Jin Ho Yoon

      $264,091

      award amount

46. Alexes Daquinag

    Leads 1 award · $195,000

    • 1R21DK138411-01Department: NIH department code

      Energizing good fat by neurovascular development
      $195,000

      award amount

47. Jessica Lan Lee

    Leads 1 award · $191,079

    • 5K23AG072042-04Department: NIH department code

      A Meal Delivery and Exercise Intervention to Increase Resilience in Homebound Older Adults
      $191,079

      award amount

48. Kendra S. Carmon

    Leads 1 award · $178,843

    • 1R21CA282378-01A1Department: NIH department code

      Bispecific drug-conjugates for treating colorectal cancer
      $178,843

      award amount

49. Brian Skaug

    Leads 1 award · $164,160

    • 5K08AR081402-03Department: NIH department code

      Pathogenic effects of the DNASE1L3 R206C variant in systemic sclerosis
      $164,160

      award amount

50. Mark Chiawei Hwang

    Leads 1 award · $162,540

    • 1K23AR083506-01Department: NIH department code

      Molecular Profiling of Spinal Disease Progression in Ankylosing Spondylitis
      $162,540

      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.

• Amelie G Ramirez

  Co-investigator on 5UM1TR004538-02, led by Robert A Clark

  From the FY2024 awards this person leads

  • UT Health Science Center Houston · Public Health (NIH department code, 1 award)
  • UT Health Science Center Houston (no department on record, 1 award)

• Jennifer Sharpe Potter

  Co-investigator on 5UM1TR004538-02, led by Robert A Clark

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Kenneth M Hargreaves

  Co-investigator on 5UM1TR004538-02, led by Robert A Clark

  From the FY2024 awards this person leads

  • UT Health Science Center Houston · Dentistry (NIH department code, 1 award)

• Alison G Cahill

  Co-investigator on 5K12TR004529-02, led by Joel Tsevat; 3K12TR004529-02S1, led by Joel Tsevat

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Sigall Bell

  Co-investigator on 5R18HS029362-03, led by Eric J Thomas

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Alice Soragni

  Co-investigator on 5R01CA264248-04, led by Patricia Leal Dahia; 3R01CA264248-04S2, led by Patricia Leal Dahia; 3R01CA264248-04S1, led by Patricia Leal Dahia

  From the FY2024 awards this person leads

  • University of California, Los Angeles · Orthopedics (NIH department code, 2 awards)

• Christopher R Anderton

  Co-investigator on 5U01DK114920-08, led by Kumar Sharma

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Theodore Alexandrov

  Co-investigator on 5U01DK114920-08, led by Kumar Sharma

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Jeffrey L. Dupree

  Co-investigator on 1R01AG085545-01, led by Xianlin Han

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Lizhen Chen

  Co-investigator on 1R01AG085545-01, led by Xianlin Han

  From the FY2024 awards this person leads

  • UT Health Science Center Houston · Anatomy & Cell Biology (NIH department code, 1 award)

• Alexander Gusev

  Co-investigator on 7R01CA244569-05, led by Simon Andrew Gayther

  From the FY2024 awards this person leads

  • Dana-Farber Cancer Institute (no department on record, 1 award)

• Jiande Chen

  Co-investigator on 5R01AR081382-02, led by Zsuzsanna Hortobagyi McMahan

  From the FY2024 awards this person leads

  • University of Michigan · Internal Medicine (NIH department code, 2 awards)

• Matthew L Freedman

  Co-investigator on 7R01CA259058-03, led by Simon Andrew Gayther

  From the FY2024 awards this person leads

  • Dana-Farber Cancer Institute (no department on record, 3 awards)

• Siddhartha Kar

  Co-investigator on 7R01CA259058-03, led by Simon Andrew Gayther

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Carolyn Black Becker

  Co-investigator on 1R01AG086777-01, led by Lisa Kilpela

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Mona Mohsen

  Co-investigator on 5R01CA276513-02, led by Eva M. Sevick

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Zhongming Zhao

  Co-investigator on 5R01CA276513-02, led by Eva M. Sevick

  From the FY2024 awards this person leads

  • UT Health Science Center Houston · Other Basic Sciences (NIH department code, 1 award)
  • UT Health Science Center Houston (no department on record, 2 awards)

• Banghe Zhu

  Co-investigator on 5R01NS126437-03, led by Eva M. Sevick

  From the FY2024 awards this person leads

  • UT Health Science Center Houston · Miscellaneous (NIH department code, 1 award)

• Manish Narendra Shah

  Co-investigator on 5R01NS126437-03, led by Eva M. Sevick

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Joseph A. Baur

  Co-investigator on 5R01DK135179-02, led by Madesh Muniswamy

  From the FY2024 awards this person leads

  • University of Pennsylvania · Physiology (NIH department code, 1 award)

• Melissa Laird Smith

  Co-investigator on 5R01HG011252-04, led by Peter A Doris

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Theodore Kalbfleisch

  Co-investigator on 5R01HG011252-04, led by Peter A Doris

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Pooja Shivshankar

  Co-investigator on 5R01AI158694-04, led by Kristin Eckel Mahan

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Gail L. Matters

  Co-investigator on 5R25DK078381-18, led by William Brian Reeves

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Ruben A. Mesa

  Co-investigator on 5R01CA262041-04, led by Jennifer Lynne Huberty

  From the FY2024 awards this person leads

  • Wake Forest University Health Sciences · Internal Medicine (NIH department code, 4 awards)
  • UT Health Science Center Houston (no department on record, 1 award)
  • Wake Forest University Health Sciences (no department on record, 1 award)

• Minghua Wu

  Co-investigator on 5R01AR081280-02, led by Shervin Assassi

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Jin Ho Yoon

  Co-investigator on 1R34DA060078-01A1, led by Chukwuemeka Nkemakonam Okafor

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.