Pathology at Washington University in St. Louis

Leads a grant in this department

42 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Kipnis, Jonathan

   Leads 4 awards · $5,326,032

   • 1P01AG078106-01Department: NIH department code

     Neuroimmunology of AD and CAA with focus on innate immunity and lymphatics
     $3,095,865

     award amount
   • 5DP1AT010416-05Department: NIH department code

     Neural code of the immune responses
     $1,102,500

     award amount
   • 1R01AG078667-01Department: NIH department code

     Aged T-cell-derived cytokines impact meningeal lymphatics and contribute to AD
     $585,577

     award amount
   • 5R37AG034113-13Department: NIH department code

     Immune system supports brain function
     $542,090

     award amount

2. Cicek, Mine

   Leads 1 award · $3,718,673

   • 5U24CA196171-08Department: NIH department code

     The Alliance NCTN Biorepository and Biospecimen Resource
     $3,718,673

     award amount

3. Randolph, Gwendalyn J

   Leads 6 awards · $3,144,140

   • 5DP1DK130660-02Department: NIH department code

     Defining the lymphatic basis of protein losing enteropathy after Fontan palliation or inflammatory gut disease
     $771,525

     award amount
   • 1R01AI168044-01Department: NIH department code

     Mechanisms that alter lymphatic transport in inflammatory bowel disease
     $568,260

     award amount
   • 5T32AI007163-44Department: NIH department code

     Training Program in Immunology
     $533,077

     award amount
   • 5U01AI163064-02Department: NIH department code

     Gut region-specific mechanisms that limit dissemination of microbial signals from the intestine
     $441,001

     award amount
   • 5R01DK119147-04Department: NIH department code

     Lymphatic remodeling and transport of dietary fats in short gut syndrome
     $436,527

     award amount
   • 5R37AI049653-22Department: NIH department code

     Differentiation and Function of Monocytes and Macrophages
     $393,750

     award amount

4. Colonna, Marco

   Leads 7 awards · $3,092,785

   • 5R01AI134035-05Department: NIH department code

     CIS-REGULATORY CIRCUITS FOR ILC FUNCTION AND PLASTICITY
     $639,023

     award amount
   • 1R01AI158579-01A1Department: NIH department code

     Ontogenetic niche of B cells at the CNS borders in homeostasis, aging and autoimmunity
     $624,511

     award amount
   • 5R01CA262684-02Department: NIH department code

     Targeting TREM2 to boost anti-cancer therapy
     $432,265

     award amount
   • 1R21AG077244-01Department: NIH department code

     Soluble TREM2 regulation of microglial function in Alzheimer disease
     $430,625

     award amount
   • 5R01DK126969-02Department: NIH department code

     MICROBIOTA-DEPENDENT CONTROL OF CLOSTRIDIUM DIFFICILE: THE ROLE OF ACETATE AND IL-22 BINDING PROTEIN
     $415,111

     award amount
   • 5R01DK124699-03Department: NIH department code

     Plasticity of Innate Lymphoid Cells: Mechanisms and Biological Impact
     $354,375

     award amount
   • 1R21AI159210-01A1Department: NIH department code

     Impact of polyamines on ILC3 function at steady state and in preclinical model of colitis
     $196,875

     award amount

5. Amarasinghe, Gaya K.

   Leads 4 awards · $2,559,918

   • 5R01AI143292-04Department: NIH department code

     Novel VP30-host Interactions that Negatively Regulate Ebola Virus Infection
     $774,291

     award amount
   • 5R01AI161765-02Department: NIH department code

     Identification and Characterization of Entry Factors Critical for Rift Valley Fever Virus Infection and Pathogenesis
     $742,007

     award amount
   • 5R01AI161374-02Department: NIH department code

     Development and characterization of engineered therapeutic antibodies against SARS-CoV-2
     $649,870

     award amount
   • 3R01AI161374-02S1Department: NIH department code

     Development and characterization of engineered therapeutic antibodies against SARS-CoV-2
     $393,750

     award amount

6. Dantas, Gautam

   Leads 3 awards · $2,146,117

   • 5R01AI155893-02Department: NIH department code

     Impact of early-life perturbations on pediatric microbiome maturation
     $753,774

     award amount
   • 5U01AI123394-07Department: NIH department code

     Structural, mechanistic, & evolutionary characterization of tetracycline destructases
     $709,070

     award amount
   • 5R01AT009741-05Department: NIH department code

     Tunable therapeutic modulation of the gut microbiome by engineered probiotics
     $683,273

     award amount

7. Murphy, Kenneth M

   Leads 5 awards · $1,967,079

   • 1R01AI162643-01A1Department: NIH department code

     Molecular Basis of cDC1 Development
     $559,854

     award amount
   • 5R01AI150297-04Department: NIH department code

     Function of Wdfy4 in cross-presentation and immunity
     $507,323

     award amount
   • 5R01CA248919-02Department: NIH department code

     Understanding the Mechanisms of DC Licensing in CD8 T Cell Priming
     $466,777

     award amount
   • 5R21AI164142-02Department: NIH department code

     Mechanism of c-MYC repression by IRF8 in myeloid lineages
     $236,250

     award amount
   • 1R21AI163421-01A1Department: NIH department code

     Transcriptional basis of embryonic macrophage development
     $196,875

     award amount

8. Corbo, Joseph

   Leads 3 awards · $1,934,000

   • 5R01HL149961-03Department: NIH department code

     High-throughput identification of causal variants underlying cardiac arrhythmia-related GWAS hits
     $722,652

     award amount
   • 5R01MH122451-03Department: NIH department code

     High-throughput identification of causal variants underlying neuropsychiatric disease-related GWAS hits
     $684,962

     award amount
   • 5R01EY030075-03Department: NIH department code

     Elucidating the cis-regulatory grammar of human photoreceptors
     $526,386

     award amount

9. Choi, Kyunghee

   Leads 2 awards · $1,227,781

   • 5R01HL055337-25Department: NIH department code

     HEMANGIOBLAST DEVELOPMENT AND REGULATION
     $711,098

     award amount
   • 5R01HL149954-03Department: NIH department code

     Epigenetic regulations of macrophage development
     $516,683

     award amount

10. Gordon, Jeffrey I

    Leads 1 award · $1,006,591

    • 5R01DK131107-02Department: NIH department code

      The small intestinal microbiota in undernourished women and undernourished children in Bangladesh: identifying causal mechanisms and therapeutic targets
      $1,006,591

      award amount

11. Edelson, Brian Todd

    Leads 2 awards · $875,417

    • 1R01AI162918-01A1Department: NIH department code

      Role of Intestinal Parasites on Regulating Immune Responses to Gut Antigens
      $639,167

      award amount
    • 1R21AI168706-01Department: NIH department code

      Selective induction of alloantigen-specific humoral tolerance by MHC-Fc fusion proteins
      $236,250

      award amount

12. Mosammaparast, Nima

    Leads 2 awards · $719,657

    • 5R01CA193318-08Department: NIH department code

      Damaged RNA as a mediator of alkylation responses
      $366,581

      award amount
    • 5R01CA227001-05Department: NIH department code

      A SIGNALING PATHWAY SPECIFIC FOR ALKYLATION DAMAGE
      $353,076

      award amount

13. Liu, Ta-Chiang

    Leads 2 awards · $715,943

    • 5R01DK124274-03Department: NIH department code

      Paneth cell phenotype as a predictive biomarker for ulcerative colitis
      $361,568

      award amount
    • 5R01DK125296-03Department: NIH department code

      Cellular and molecular mechanisms of cigarette smoking-induced Paneth cell abnormality
      $354,375

      award amount

14. Klechevsky, Eynav Yafit

    Leads 2 awards · $696,111

    • 5R01CA245277-03Department: NIH department code

      The Role of CD5 in Tumor Immunity
      $353,076

      award amount
    • 5R01AR075959-04Department: NIH department code

      Harnessing Human Dendritic Cell Subsets in Skin for the Design of Novel Immunotherapies
      $343,035

      award amount

15. Ellebedy, Ali Hassan

    Leads 1 award · $667,595

    • 5U01AI141990-04Department: NIH department code

      Programming Durable Immune Responses To Vaccination
      $667,595

      award amount

16. Ravichandran, Kodi S

    Leads 1 award · $583,731

    • 7R01AI159551-03Department: NIH department code

      Solute carrier proteins in efferocytosis and inflammation
      $583,731

      award amount

17. Wan, Xiaoxiao

    Leads 1 award · $471,535

    • 1R01AI162591-01A1Department: NIH department code

      Autoimmune Diabetes: Macrophage Responses
      $471,535

      award amount

18. Teitelbaum, Steven L

    Leads 1 award · $457,219

    • 1R01CA258325-01A1Department: NIH department code

      Hepatic steatosis promotes liver metastasis
      $457,219

      award amount

19. Van Dyken, Steven

    Leads 1 award · $421,780

    • 5R01HL148033-03Department: NIH department code

      Targeting chitin in fibrotic lung disease
      $421,780

      award amount

20. Hanrieder, Jorg

    Leads 1 award · $410,984

    • 1R21AG078538-01Department: NIH department code

      Human in vivo stable isotope labeling kinetics (iSILK) to quantify brain amyloid plaque kinetics
      $410,984

      award amount

21. Schreiber, Robert David

    Leads 1 award · $394,366

    • 2T32CA009547-36A1Department: NIH department code

      TRAINING IN THE IMMUNOBIOLOGY AND MOLECULAR CELL BIOLOGY OF CANCER
      $394,366

      award amount

22. Brestoff, Jonathan R

    Leads 1 award · $393,750

    • 5DP5OD028125-04Department: NIH department code

      Regulation of innate immune cell responses through cell-to-cell transfer of mitochondria
      $393,750

      award amount

23. Grajales-Reyes, Gary E.

    Leads 1 award · $392,916

    • 1DP5OD033428-01Department: NIH department code

      CAR-based approaches for the treatment of Alzheimer's Disease
      $392,916

      award amount

24. Miller, Grover P

    Leads 1 award · $374,783

    • 5R01GM140635-03Department: NIH department code

      Systematic Discovery of Bioactivation-Associated Structural Alerts
      $374,783

      award amount

25. Egawa, Takeshi

    Leads 3 awards · $354,375

    • 5R21AI161040-02Department: NIH department code

      Identification of progenitor CD4 T cells that support response to chronic antigen
      $196,875

      award amount
    • 1R03AI166404-01Department: NIH department code

      Development of a novel mouse model with progesterone-independent susceptibility to genital HSV infection
      $78,750

      award amount
    • 1R03AI166801-01Department: NIH department code

      Developing tools to study relationship between oxidative stress in T cell dysfunction
      $78,750

      award amount

26. Duncavage, Eric J

    Leads 1 award · $261,450

    • 1UH2CA272904-01Department: NIH department code

      Whole Genome Sequencing for Genomic Evaluation and Risk Stratification of Patients with Myelodysplastic Syndromes
      $261,450

      award amount

27. Lorenz, Ulrike

    Leads 1 award · $186,104

    • 7R21CA267955-02Department: NIH department code

      A New Approach to Modulating CAR T Cell Activity
      $186,104

      award amount

28. Artomov, Maksym

    Leads 1 award · $173,067

    • 1R21AR080233-01A1Department: NIH department code

      The Malate-Aspartate shuttle links dietary fatty acids to inflammatory responses in dendritic cells
      $173,067

      award amount

29. Wilson, Parker C.

    Leads 1 award · $167,826

    • 1K08DK126847-01A1Department: NIH department code

      The Single Cell Landscape of Early Human Diabetic Nephropathy
      $167,826

      award amount

30. Wesener, Darryl A

    Leads 1 award · $108,275

    • 5K99AT011374-02Department: NIH department code

      Human gut bacterial cell surface polysaccharides as a microbial nutrient source and target of immunoregulatory proteins shape gut microbiota structure and function
      $108,275

      award amount

31. Han, Jichang

    Leads 1 award · $89,021

    • 4K00CA264434-02Department: NIH department code

      Deciphering the role of tumor-macrophage crosstalk during metastatic dissemination to the peritoneum
      $89,021

      award amount

32. Qavi, Abraham Jaleel

    Leads 1 award · $73,072

    • 1K08EB033409-01Department: NIH department code

      Development of Optofluidic Resonators for Filoviral Detection
      $73,072

      award amount

33. Chen, Robert Yuzen

    Leads 1 award · $51,752

    • 5F30DK124967-03Department: NIH department code

      Unraveling the biological state of children with Environmental enteric dysfunction
      $51,752

      award amount

34. Beller, Zachary Walter

    Leads 1 award · $45,164

    • 5F30DK123838-03Department: NIH department code

      Impact of Gut Bacterial Interactions on the Response to Fiber-Based Prebiotics
      $45,164

      award amount

35. Peng, Vincent

    Leads 1 award · $42,968

    • 5F30DK127540-03Department: NIH department code

      Determining the contribution of polyamine biosynthesis to the function of group 3 innate lymphoid cells in the gastrointestinal system
      $42,968

      award amount

36. Kelley, Shannon

    Leads 1 award · $35,508

    • 5F31HL160134-03Department: NIH department code

      Testing the tyrosine phosphatase SHP-2 as a novel brake on efferocytosis
      $35,508

      award amount

37. Barron, Brady

    Leads 1 award · $33,122

    • 7F31DK125005-03Department: NIH department code

      Understanding Phagocytosis Within the Adipose Tissue
      $33,122

      award amount

38. Diorio-Toth, Luke Evan

    Leads 1 award · $32,686

    • 5F30AI157161-02Department: NIH department code

      Mapping the evolutionary landscape of a novel family of tetracycline resistance enzymes
      $32,686

      award amount

39. Kao, Clara

    Leads 1 award · $32,686

    • 1F30DK132805-01Department: NIH department code

      CHARACTERIZATION OF THE ROLE OF THE SMALL INTESTINAL MICROBIOTA IN THE PATHOGENESIS OF ENVIRONMENTAL ENTERIC DYSFUNCTION IN UNDERNOURISHED CHILDREN AND MOTHERS
      $32,686

      award amount

40. Wu, Renee Paula

    Leads 1 award · $32,686

    • 5F30CA247262-02Department: NIH department code

      The role of type 1 dendritic cells in CD4 and CD8 T cell anti-tumor immunity
      $32,686

      award amount

41. Zhou, Cyrus

    Leads 1 award · $32,686

    • 1F30DK131866-01A1Department: NIH department code

      Mechanism of action of a microbiota-directed complementary food that promotes ponderal growth in Bangladeshi children with moderate acute malnutrition
      $32,686

      award amount

42. Townley, Brittany A

    Leads 1 award · $8,526

    • 5F31CA254143-03Department: NIH department code

      Regulation of RNA processing by the novel spliceosomal protein, TTDN1, in development and cancer
      $8,526

      award amount