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FY2024 NIH awards · Principal investigators

Pathology at Washington University in St. Louis

St. Louis, MO

Funding
$30.4M
$30,388,021
Awards
70
FY2024 NIH awards in Pathology
Principal investigators
60
42 lead a grant here, 18 co-investigators
Department rank
#5
of 94 · Ranking
  • NIH names only the principal investigators on an award, so this page lists only them. The department is the award's: it is where ScienceDex counts the award, not a list of the department's members.
  • These are the awards in the Pathology row of the Washington University in St. Louis page.

Leads a grant in this department

42 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

  1. Marco Colonna

    Leads 8 awards · $4,118,416

    • 1R01AG081631-01A1Department: NIH department code
      Spontaneous and Induced B cell and T cell responses in Alzheimer's Disease
      $775,250
      award amount
    • 5R01DK132327-02Department: NIH department code
      Mucosal Immune Defense Mechanisms of the Urinary Bladder

      Principal investigators: Marco Colonna (contact PI), Scott J. Hultgren

      $594,739
      award amount
    • 5R01AI158579-03Department: NIH department code
      Ontogenetic niche of B cells at the CNS borders in homeostasis, aging and autoimmunity

      Principal investigators: Marco Colonna (contact PI), Alessandra B Pernis

      $587,914
      award amount
    • 4R01AG051485-03Department: NIH department code
      TREM2 IN MICROGLIA BIOLOGY AND ALZHEIMER'S DISEASE
      $533,486
      award amount
    • 1R21AG085133-01A1Department: NIH department code
      Elucidating the mechanisms by which microgliopathy causes early-onset dementia
      $427,625
      award amount
    • 5R01CA262684-04Department: NIH department code
      Targeting TREM2 to boost anti-cancer therapy
      $419,032
      award amount
    • 1R21CA273885-01A1Department: NIH department code
      ILT3 (LILRB4) in anti-tumor immunity and immunotherapy
      $391,277
      award amount
    • 5R01DK126969-04Department: NIH department code
      MICROBIOTA-DEPENDENT CONTROL OF CLOSTRIDIUM DIFFICILE: THE ROLE OF ACETATE AND IL-22 BINDING PROTEIN
      $389,093
      award amount

  2. Gautam Dantas

    Leads 4 awards · $3,232,926

    • 1U01AT012998-01Department: NIH department code
      Functional characterization of viral-bacterial-human interactions during antimicrobial and inflammatory perturbations across different lifespans

      Principal investigators: Gautam Dantas (contact PI), Megan T Baldridge

      $1,035,406
      award amount
    • 5R01AI155893-04Department: NIH department code
      Impact of early-life perturbations on pediatric microbiome maturation
      $769,606
      award amount
    • 1R01AI184858-01Department: NIH department code
      High-resolution genomic interrogation of pathogen-microbiome interactions in Clostridioides difficile infection

      Principal investigators: Gautam Dantas (contact PI), Erik R Dubberke

      $746,205
      award amount
    • 5U01AI123394-09Department: NIH department code
      Structural, mechanistic, & evolutionary characterization of tetracycline destructases

      Principal investigators: Gautam Dantas (contact PI), Timothy Adam Wencewicz

      $681,709
      award amount

  3. Gwendalyn J Randolph

    Leads 5 awards · $2,716,587

    • 5DP1DK130660-04Department: NIH department code
      Defining the lymphatic basis of protein losing enteropathy after Fontan palliation or inflammatory gut disease
      $716,331
      award amount
    • 2R01DK119147-06Department: NIH department code
      Intestinally restricted LXR agonism in ameliorating liver failure in short gut syndrome

      Principal investigators: Gwendalyn J Randolph (contact PI), Ajay K. Jain, Bahaa Elgendy, Brad Wayne Warner

      $604,462
      award amount
    • 5R01AI168044-03Department: NIH department code
      Mechanisms that alter lymphatic transport in inflammatory bowel disease
      $561,044
      award amount
    • 5U01AI163064-04Department: NIH department code
      Gut region-specific mechanisms that limit dissemination of microbial signals from the intestine
      $441,000
      award amount
    • 5R37AI049653-24Department: NIH department code
      Differentiation and Function of Monocytes and Macrophages
      $393,750
      award amount

  4. Gaya K. Amarasinghe

    Leads 3 awards · $1,697,673

    • 5R01AI169850-02Department: NIH department code
      Characterizing the role of LDL related receptor 1 (Lrp1) as host entry factor for multiple bunyaviruses

      Principal investigators: Gaya K. Amarasinghe (contact PI), Amy L Hartman

      $767,375
      award amount
    • 5R01AI161765-04Department: NIH department code
      Identification and Characterization of Entry Factors Critical for Rift Valley Fever Virus Infection and Pathogenesis

      Principal investigators: Gaya K. Amarasinghe (contact PI), Amy L Hartman

      $735,323
      award amount
    • 5R21AI176626-02Department: NIH department code
      HSP90 paralog selective small molecules as anti-old-world alpha-viral therapeutic leads.

      Principal investigators: Gaya K. Amarasinghe (contact PI), Brian S J Blagg

      $194,975
      award amount

  5. Kenneth M Murphy

    Leads 3 awards · $1,380,210

    • 5R01AI162643-03Department: NIH department code
      Molecular Basis of cDC1 Development
      $559,854
      award amount
    • 5R01CA248919-04Department: NIH department code
      Understanding the Mechanisms of DC Licensing in CD8 T Cell Priming
      $452,486
      award amount
    • 2T32AI007163-46Department: NIH department code
      Training Program in Basic Immunology

      Principal investigators: Kenneth M Murphy (contact PI), Kodi S Ravichandran

      $367,870
      award amount

  6. Kyunghee Choi

    Leads 2 awards · $1,215,075

    • 5R01HL055337-27Department: NIH department code
      HEMANGIOBLAST DEVELOPMENT AND REGULATION
      $696,876
      award amount
    • 5R01CA271714-02Department: NIH department code
      Myct1 control of the angioimmune interface

      Principal investigators: Kyunghee Choi (contact PI), Changwon Park

      $518,199
      award amount

  7. Joseph Corbo

    Leads 2 awards · $1,184,149

    • 5R01MH122451-05Department: NIH department code
      High-throughput identification of causal variants underlying neuropsychiatric disease-related GWAS hits
      $680,135
      award amount
    • 5R01EY033810-02Department: NIH department code
      Targeting Nr2e3 to prevent photoreceptor degeneration

      Principal investigators: Joseph Corbo (contact PI), Vladimir Jivkov Kefalov

      $504,014
      award amount

  8. Mark A. Watson

    Leads 1 award · $1,167,765

  9. Takeshi Egawa

    Leads 2 awards · $1,149,440

    • 1R01AI176664-01A1Department: NIH department code
      Molecular mechanisms of CD8 T cell fate decision instructed by cytokine signaling
      $583,619
      award amount
    • 5R01AI130152-07Department: NIH department code
      The transcription factor c-MYC in lymphocyte expansion and restriction of stemness
      $565,821
      award amount

  10. Jonathan Kipnis

    Leads 2 awards · $1,110,300

    • 5R01AG078667-03Department: NIH department code
      Aged T-cell-derived cytokines impact meningeal lymphatics and contribute to AD
      $578,141
      award amount
    • 5R37AG034113-15Department: NIH department code
      Immune system supports brain function
      $532,159
      award amount

  11. Xiaoxiao Wan

    Leads 2 awards · $1,052,731

    • 5R01DK134437-02Department: NIH department code
      The role of beta-cell crinophagy in generating diabetogenic neoepitopes
      $587,184
      award amount
    • 5R01AI162591-03Department: NIH department code
      Autoimmune Diabetes: Macrophage Responses
      $465,547
      award amount

  12. Steven Van Dyken

    Leads 2 awards · $1,042,260

    • 5R01AI176660-02Department: NIH department code
      Defining the role of IL-18 in atopic dermatitis

      Principal investigators: Steven Van Dyken (contact PI), Brian Kim

      $809,010
      award amount
    • 5R21AI163640-02Department: NIH department code
      Chitin and chitinases in SARS-CoV-2 infection
      $233,250
      award amount

  13. Jeffrey I Gordon

    Leads 1 award · $994,651

    • 5R01DK131107-04Department: NIH department code
      The small intestinal microbiota in undernourished women and undernourished children in Bangladesh: identifying causal mechanisms and therapeutic targets
      $994,651
      award amount

  14. Ta-Chiang Liu

    Leads 2 awards · $971,636

    • 5R01DK136829-02Department: NIH department code
      Dietary modulation of Paneth cells
      $542,456
      award amount
    • 1R01DK138465-01A1Department: NIH department code
      Macrophage LRRK2 activity regulates gut epithelial homeostasis
      $429,180
      award amount

  15. Nima Mosammaparast

    Leads 2 awards · $844,895

    • 1R01CA282733-01A1Department: NIH department code
      An RNA-Dependent Innate Immune Response Pathway to Base-Damaging Chemotherapeutics
      $489,536
      award amount
    • 5R01CA193318-10Department: NIH department code
      Damaged RNA as a mediator of alkylation responses
      $355,359
      award amount

  16. Brian Todd Edelson

    Leads 1 award · $631,050

    • 5R01AI162918-03Department: NIH department code
      Role of Intestinal Parasites on Regulating Immune Responses to Gut Antigens

      Principal investigators: Brian Todd Edelson (contact PI), Chyi S Hsieh

      $631,050
      award amount

  17. Jonathan R Brestoff

    Leads 2 awards · $619,783

    • 1R01NS134932-01A1Department: NIH department code
      Harnessing mitochondria transfer pathways to ameliorate Leigh Syndrome-like disease
      $596,783
      award amount
    • 1R13HL176131-01Department: NIH department code
      2024 Kern Lipid Conference: "Lipids and Mitochondria in Cardiometabolic Diseases"
      $23,000
      award amount

  18. Ali Hassan Ellebedy

    Leads 1 award · $593,729

    • 2U01AI141990-06Department: NIH department code
      Programming Durable Immune Responses To Vaccination
      $593,729
      award amount

  19. Kodi S Ravichandran

    Leads 1 award · $576,319

    • 5R01AI159551-05Department: NIH department code
      Solute carrier proteins in efferocytosis and inflammation
      $576,319
      award amount

    Also a principal investigator on 2T32AI007163-46, led by Kenneth M Murphy.

  20. Steven L Teitelbaum

    Leads 1 award · $492,873

    • 5R01CA258325-03Department: NIH department code
      Hepatic steatosis promotes liver metastasis
      $492,873
      award amount

  21. Robert David Schreiber

    Leads 1 award · $416,112

    • 5T32CA009547-38Department: NIH department code
      TRAINING IN THE IMMUNOBIOLOGY AND MOLECULAR CELL BIOLOGY OF CANCER
      $416,112
      award amount

  22. Gary E. Grajales-Reyes

    Leads 1 award · $388,750

    • 5DP5OD033428-03Department: NIH department code
      CAR-based approaches for the treatment of Alzheimer's Disease
      $388,750
      award amount

  23. Eric J Duncavage

    Leads 1 award · $367,837

    • 5R33CA278510-02Department: NIH department code
      A Rapid and Comprehensive Approach for Clinical Genomic Profiling in Lung Cancer

      Principal investigators: Eric J Duncavage (contact PI), David H Spencer

      $367,837
      award amount

  24. Eynav Yafit Klechevsky

    Leads 1 award · $342,268

    • 5R01CA245277-05Department: NIH department code
      The Role of CD5 in Tumor Immunity
      $342,268
      award amount

  25. Sarah D Ackerman

    Leads 2 awards · $333,410

    • 5R00NS121137-04Department: NIH department code
      The role of astrocyte-neuron signaling in closing a critical period required for motor circuit structure function and behavior
      $224,100
      award amount
    • 3R00NS121137-04S1Department: NIH department code
      The role of astrocyte-neuron signaling in closing a critical period required for motor circuit structure function and behavior
      $109,310
      award amount

  26. Aayushi Uberoi

    Leads 1 award · $249,000

    • 4R00AR081404-03Department: NIH department code
      Decoding microbial-Aryl Hydrocarbon Receptor interactions at the skin barrier interface
      $249,000
      award amount

  27. Claudia Z Han

    Leads 1 award · $224,100

    • 4R00MH129983-03Department: NIH department code
      Gene regulatory networks influencing neuron-microglia interactions in fetal brain development.
      $224,100
      award amount

  28. Ulrike Lorenz

    Leads 1 award · $172,654

    • 5R21CA267955-03Department: NIH department code
      A New Approach to Modulating CAR T Cell Activity
      $172,654
      award amount

  29. Stephen Phillip Persaud

    Leads 1 award · $169,156

    • 1K08HL168155-01A1Department: NIH department code
      Optimizing hematopoietic stem cell transplantation to treat non-malignant disease
      $169,156
      award amount

  30. Yi Wang

    Leads 1 award · $142,429

    • 5K01DK134840-02Department: NIH department code
      Key gut microbes shape intestinal epithelial lineage development, differentiation and metabolic function
      $142,429
      award amount

  31. Skye Rebecca Fishbein

    Leads 1 award · $126,333

    • 1K99AI175674-01A1Department: NIH department code
      Identifying sources of variation in microbiome-pathogen dynamics during Clostridioides difficile colonization
      $126,333
      award amount

  32. Miranda Wallace

    Leads 1 award · $120,866

    • 1K99AT012651-01Department: NIH department code
      Expanding the therapeutic capacity of Saccharomyces cerevisiae var. boulardii for the treatment of gastrointestinal infections
      $120,866
      award amount

  33. Jichang Han

    Leads 1 award · $103,352

    • 5K00CA264434-04Department: NIH department code
      Deciphering the role of tumor-macrophage crosstalk during metastatic dissemination to the peritoneum
      $103,352
      award amount

  34. Maggie Postolache

    Leads 1 award · $83,328

    • 1F32MH139159-01Department: NIH department code
      Long-term neural consequences of altered critical period timing.
      $83,328
      award amount

  35. Clara Kao

    Leads 1 award · $53,974

    • 5F30DK132805-03Department: NIH department code
      CHARACTERIZATION OF THE ROLE OF THE SMALL INTESTINAL MICROBIOTA IN THE PATHOGENESIS OF ENVIRONMENTAL ENTERIC DYSFUNCTION IN UNDERNOURISHED CHILDREN AND MOTHERS
      $53,974
      award amount

  36. Cyrus Zhou

    Leads 1 award · $53,974

    • 5F30DK131866-03Department: NIH department code
      Mechanism of action of a microbiota-directed complementary food that promotes ponderal growth in Bangladeshi children with moderate acute malnutrition
      $53,974
      award amount

  37. Rachel Mintz

    Leads 1 award · $53,974

    • 5F30CA281124-02Department: NIH department code
      Mechanisms Underlying the Omental Support of Ovarian Cancer Peritoneal Metastasis
      $53,974
      award amount

  38. Jing Chen

    Leads 1 award · $53,463

    • 5F30HL167565-02Department: NIH department code
      The role of EMT transcription factor Zeb2 in fetal hematopoiesis
      $53,463
      award amount

  39. Reyan Coskun

    Leads 1 award · $35,542

    • 1F30HD115307-01Department: NIH department code
      Modeling the effects of the gut microbiota of undernourished mothers with environmental enteric dysfunction on vascular remodeling at the fetal-placental interface
      $35,542
      award amount

  40. Jasmine Wright

    Leads 1 award · $35,482

    • 1F31AI183832-01Department: NIH department code
      Immunometabolic regulation of enteric viral infection
      $35,482
      award amount

  41. Maegan Murphy

    Leads 1 award · $34,926

    • 5F31AI174696-02Department: NIH department code
      Defining the regulation and regulatory mechanisms of TCF-1 in CD8+ T cell differentiation
      $34,926
      award amount

  42. Grace Uwase

    Leads 1 award · $34,623

    • 1F30AI181462-01Department: NIH department code
      Defining how ubiquitination of Ebola viral proteins affect host-viral dynamics
      $34,623
      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.