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FY2025 NIH awards · Principal investigators

Pathology at Washington University in St. Louis

St. Louis, MO

Funding
$37.3M
$37,342,545
Awards
76
FY2025 NIH awards in Pathology
Principal investigators
68
46 lead a grant here, 22 co-investigators
Department rank
#4
of 88 · Ranking
  • NIH names only the principal investigators on an award, so this page lists only them. The department is the award's: it is where ScienceDex counts the award, not a list of the department's members.
  • These are the awards in the Pathology row of the Washington University in St. Louis page.

Leads a grant in this department

46 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

  1. Marco Colonna

    Leads 6 awards · $3,655,070

    • 5R01AG081631-02Department: NIH department code
      Spontaneous and Induced B cell and T cell responses in Alzheimer's Disease
      $759,744
      award amount
    • 2R01AI134035-06Department: NIH department code
      Cis-Regulatory Circuits for ILC Function and Plasticity

      Principal investigators: Marco Colonna (contact PI), Eugene M Oltz

      $750,844
      award amount
    • 5R01DK132327-03Department: NIH department code
      Mucosal Immune Defense Mechanisms of the Urinary Bladder

      Principal investigators: Marco Colonna (contact PI), Scott J. Hultgren

      $619,518
      award amount
    • 5R01AI158579-04Department: NIH department code
      Ontogenetic niche of B cells at the CNS borders in homeostasis, aging and autoimmunity

      Principal investigators: Marco Colonna (contact PI), Alessandra B Pernis

      $561,061
      award amount
    • 5R01AG051485-04Department: NIH department code
      TREM2 IN MICROGLIA BIOLOGY AND ALZHEIMER'S DISEASE
      $522,816
      award amount
    • 5R01CA262684-05Department: NIH department code
      Targeting TREM2 to boost anti-cancer therapy
      $441,087
      award amount

  2. Kenneth M Murphy

    Leads 5 awards · $3,262,301

    • 4R01AI162643-04Department: NIH department code
      Molecular Basis of cDC1 Development
      $1,108,321
      award amount
    • 1R01AI191447-01Department: NIH department code
      Role of WDFY4 in Treg development

      Principal investigators: Kenneth M Murphy (contact PI), Chyi S Hsieh

      $737,502
      award amount
    • 2R37AI150297-06A1Department: NIH department code
      Function of Wdfy4 in cross-presentation and immunity
      $569,250
      award amount
    • 5R01CA248919-05Department: NIH department code
      Understanding the Mechanisms of DC Licensing in CD8 T Cell Priming
      $463,700
      award amount
    • 5T32AI007163-47Department: NIH department code
      Training Program in Basic Immunology

      Principal investigators: Kenneth M Murphy (contact PI), Kodi S Ravichandran

      $383,528
      award amount

  3. Gautam Dantas

    Leads 4 awards · $3,217,177

    • 5U01AT012998-02Department: NIH department code
      Functional characterization of viral-bacterial-human interactions during antimicrobial and inflammatory perturbations across different lifespans

      Principal investigators: Gautam Dantas (contact PI), Megan T Baldridge

      $1,040,503
      award amount
    • 5R01AI155893-05Department: NIH department code
      Impact of early-life perturbations on pediatric microbiome maturation
      $759,369
      award amount
    • 5R01AI184858-02Department: NIH department code
      High-resolution genomic interrogation of pathogen-microbiome interactions in Clostridioides difficile infection

      Principal investigators: Gautam Dantas (contact PI), Erik R Dubberke

      $745,133
      award amount
    • 5U01AI123394-10Department: NIH department code
      Structural, mechanistic, & evolutionary characterization of tetracycline destructases

      Principal investigators: Gautam Dantas (contact PI), Timothy Adam Wencewicz

      $672,172
      award amount

  4. Mark A. Watson

    Leads 1 award · $2,849,375

  5. Gwendalyn J Randolph

    Leads 5 awards · $2,707,391

    • 5DP1DK130660-05Department: NIH department code
      Defining the lymphatic basis of protein losing enteropathy after Fontan palliation or inflammatory gut disease
      $737,841
      award amount
    • 5R01DK119147-07Department: NIH department code
      Intestinally restricted LXR agonism in ameliorating liver failure in short gut syndrome

      Principal investigators: Gwendalyn J Randolph (contact PI), Ajay K. Jain, Bahaa Elgendy, Brad Wayne Warner

      $590,587
      award amount
    • 5R01AI168044-04Department: NIH department code
      Mechanisms that alter lymphatic transport in inflammatory bowel disease
      $544,213
      award amount
    • 5U01AI163064-05Department: NIH department code
      Gut region-specific mechanisms that limit dissemination of microbial signals from the intestine
      $441,000
      award amount
    • 5R37AI049653-25Department: NIH department code
      Differentiation and Function of Monocytes and Macrophages
      $393,750
      award amount

  6. Jonathan Kipnis

    Leads 3 awards · $1,810,619

    • 1R61AG090394-01Department: NIH department code
      Engineered T cell approaches for Alzheimer's disease

      Principal investigators: Jonathan Kipnis (contact PI), Ido Amit, Robbie G. Majzner

      $728,370
      award amount
    • 5R01AG078667-04Department: NIH department code
      Aged T-cell-derived cytokines impact meningeal lymphatics and contribute to AD
      $566,578
      award amount
    • 4R37AG034113-16Department: NIH department code
      Immune system supports brain function
      $515,671
      award amount

  7. Ta-Chiang Liu

    Leads 3 awards · $1,799,935

    • 1R01DK140932-01Department: NIH department code
      Defining the molecular mechanism of gut inflammation and barrier dysfunction in people with HIV (PWH)

      Principal investigators: Ta-Chiang Liu (contact PI), Priya Pal

      $777,336
      award amount
    • 5R01DK136829-03Department: NIH department code
      Dietary modulation of Paneth cells
      $569,241
      award amount
    • 5R01DK138465-02Department: NIH department code
      Macrophage LRRK2 activity regulates gut epithelial homeostasis
      $453,358
      award amount

  8. Gaya K. Amarasinghe

    Leads 2 awards · $1,498,427

    • 5R01AI169850-03Department: NIH department code
      Characterizing the role of LDL related receptor 1 (Lrp1) as host entry factor for multiple bunyaviruses

      Principal investigators: Gaya K. Amarasinghe (contact PI), Amy L Hartman

      $767,375
      award amount
    • 5R01AI161765-05Department: NIH department code
      Identification and Characterization of Entry Factors Critical for Rift Valley Fever Virus Infection and Pathogenesis

      Principal investigators: Gaya K. Amarasinghe (contact PI), Amy L Hartman

      $731,052
      award amount

  9. Nima Mosammaparast

    Leads 2 awards · $1,344,463

    • 1R01GM160854-01Department: NIH department code
      RNA damage induced DNA breaks: A new mechanism of genome instability
      $854,927
      award amount
    • 5R01CA282733-02Department: NIH department code
      An RNA-Dependent Innate Immune Response Pathway to Base-Damaging Chemotherapeutics
      $489,536
      award amount

  10. Jonathan R Brestoff

    Leads 2 awards · $1,300,584

    • 1R01DK140330-01A1Department: NIH department code
      Neutrophil regulation of brown adipose tissue homeostasis
      $709,931
      award amount
    • 5R01NS134932-02Department: NIH department code
      Harnessing mitochondria transfer pathways to ameliorate Leigh Syndrome-like disease
      $590,653
      award amount

  11. Brian Todd Edelson

    Leads 1 award · $1,262,100

    • 4R01AI162918-04Department: NIH department code
      Role of Intestinal Parasites on Regulating Immune Responses to Gut Antigens

      Principal investigators: Brian Todd Edelson (contact PI), Chyi S Hsieh

      $1,262,100
      award amount

  12. Eric J Huang

    Leads 2 awards · $1,185,245

    • 7R01AG081452-03Department: NIH department code
      Endolysosomal trafficking and lipid metabolism defects in FTLD
      $669,477
      award amount
    • 7R01NS132595-03Department: NIH department code
      Neuroinflammation and vascular development in GMH
      $515,768
      award amount

  13. Takeshi Egawa

    Leads 2 awards · $1,131,931

    • 5R01AI176664-02Department: NIH department code
      Molecular mechanisms of CD8 T cell fate decision instructed by cytokine signaling
      $566,110
      award amount
    • 5R01AI130152-08Department: NIH department code
      The transcription factor c-MYC in lymphocyte expansion and restriction of stemness
      $565,821
      award amount

  14. Xiaoxiao Wan

    Leads 2 awards · $1,063,231

    • 5R01DK134437-03Department: NIH department code
      The role of beta-cell crinophagy in generating diabetogenic neoepitopes
      $611,650
      award amount
    • 5R01AI162591-04Department: NIH department code
      Autoimmune Diabetes: Macrophage Responses
      $451,581
      award amount

  15. Kodi S Ravichandran

    Leads 2 awards · $986,655

    • 5R01AI159551-06Department: NIH department code
      Solute carrier proteins in efferocytosis and inflammation
      $559,030
      award amount
    • 1R21EY037063-01A1Department: NIH department code
      Hyperoxia and enhancing efferocytosis in the eye
      $427,625
      award amount

    Also a principal investigator on 5T32AI007163-47, led by Kenneth M Murphy.

  16. Jeffrey I Gordon

    Leads 1 award · $863,192

    • 2R01DK030292-39A1Department: NIH department code
      Genomic and metabolomic foundations of human-microbial symbiosis in the gut

      Principal investigators: Jeffrey I Gordon (contact PI), Andrei L Osterman

      $863,192
      award amount

  17. Steven Van Dyken

    Leads 1 award · $809,010

    • 5R01AI176660-03Department: NIH department code
      Defining the role of IL-18 in atopic dermatitis

      Principal investigators: Steven Van Dyken (contact PI), Brian Kim

      $809,010
      award amount

  18. Eric J Duncavage

    Leads 2 awards · $775,945

    • 4UH3CA272904-02Department: NIH department code
      Whole Genome Sequencing for Genomic Evaluation and Risk Stratification of Patients with Myelodysplastic Syndromes

      Principal investigators: Eric J Duncavage (contact PI), David H Spencer

      $388,750
      award amount
    • 5R33CA278510-03Department: NIH department code
      A Rapid and Comprehensive Approach for Clinical Genomic Profiling in Lung Cancer

      Principal investigators: Eric J Duncavage (contact PI), David H Spencer

      $387,195
      award amount

  19. Sarah D Ackerman

    Leads 2 awards · $712,332

    • 1R01NS144659-01Department: NIH department code
      Exploring activity-dependent regulation of intra and intercellular mitochondrial transport in astrocytes
      $488,232
      award amount
    • 5R00NS121137-05Department: NIH department code
      The role of astrocyte-neuron signaling in closing a critical period required for motor circuit structure function and behavior
      $224,100
      award amount

  20. Ali Hassan Ellebedy

    Leads 1 award · $659,699

    • 5U01AI141990-07Department: NIH department code
      Programming Durable Immune Responses To Vaccination
      $659,699
      award amount

  21. Kyunghee Choi

    Leads 1 award · $545,472

    • 5R01CA271714-03Department: NIH department code
      Myct1 control of the angioimmune interface

      Principal investigators: Kyunghee Choi (contact PI), Changwon Park

      $545,472
      award amount

  22. Joseph Corbo

    Leads 1 award · $502,086

    • 5R01EY033810-03Department: NIH department code
      Targeting Nr2e3 to prevent photoreceptor degeneration

      Principal investigators: Joseph Corbo (contact PI), Vladimir Jivkov Kefalov

      $502,086
      award amount

  23. Umang Jain

    Leads 1 award · $465,444

    • 1R01DK142751-01Department: NIH department code
      Commensal fungi promote wound repair by modulating host metabolites
      $465,444
      award amount

  24. Nidhi Rohatgi

    Leads 1 award · $436,171

    • 5R01CA258325-04Department: NIH department code
      Hepatic steatosis promotes liver metastasis
      $436,171
      award amount

  25. Robert David Schreiber

    Leads 1 award · $343,165

    • 5T32CA009547-39Department: NIH department code
      TRAINING IN THE IMMUNOBIOLOGY AND MOLECULAR CELL BIOLOGY OF CANCER
      $343,165
      award amount

  26. Jichang Han

    Leads 2 awards · $270,376

    • 1K99CA300889-01Department: NIH department code
      Dynamics and function of peritoneal myeloid cells during colorectal cancer peritoneal dissemination and implications for immunotherapy
      $166,752
      award amount
    • 5K00CA264434-05Department: NIH department code
      Deciphering the role of tumor-macrophage crosstalk during metastatic dissemination to the peritoneum
      $103,624
      award amount

  27. Lijuan Feng

    Leads 1 award · $248,994

    • 4R00HD107908-03Department: NIH department code
      Mechanisms of de novo Germline Histone Mutations Underlying Developmental Disorders
      $248,994
      award amount

  28. Sadaf Amin

    Leads 1 award · $244,020

    • 4R00AG078493-03Department: NIH department code
      Investigating the role of cGAS signaling and microglial senscence in tauopathy
      $244,020
      award amount

  29. Claudia Z Han

    Leads 1 award · $204,282

    • 5R00MH129983-04Department: NIH department code
      Gene regulatory networks influencing neuron-microglia interactions in fetal brain development.
      $204,282
      award amount

  30. Aayushi Uberoi

    Leads 1 award · $188,171

    • 5R00AR081404-04Department: NIH department code
      Decoding microbial-Aryl Hydrocarbon Receptor interactions at the skin barrier interface
      $188,171
      award amount

  31. Stephen Phillip Persaud

    Leads 1 award · $169,156

    • 5K08HL168155-02Department: NIH department code
      Optimizing hematopoietic stem cell transplantation to treat non-malignant disease
      $169,156
      award amount

  32. Yi Wang

    Leads 1 award · $142,429

    • 5K01DK134840-03Department: NIH department code
      Key gut microbes shape intestinal epithelial lineage development, differentiation and metabolic function
      $142,429
      award amount

  33. Miranda Wallace

    Leads 1 award · $120,866

    • 5K99AT012651-02Department: NIH department code
      Expanding the therapeutic capacity of Saccharomyces cerevisiae var. boulardii for the treatment of gastrointestinal infections
      $120,866
      award amount

  34. Michael Ray Strickland

    Leads 1 award · $82,552

    • 1F32DK145123-01Department: NIH department code
      Mechanisms of HDL-Mediated LPS Neutralization and Transport in the Portal Vein
      $82,552
      award amount

  35. Jing Chen

    Leads 1 award · $54,538

    • 5F30HL167565-03Department: NIH department code
      The role of EMT transcription factor Zeb2 in fetal hematopoiesis
      $54,538
      award amount

  36. Jose Alejandro Mazzitelli Perez

    Leads 1 award · $54,538

    • 5F30HD112122-02Department: NIH department code
      The role of skull bone marrow-derived CNS macrophages in Rett syndrome.
      $54,538
      award amount

  37. Rachel Mintz

    Leads 1 award · $54,538

    • 5F30CA281124-03Department: NIH department code
      Mechanisms Underlying the Omental Support of Ovarian Cancer Peritoneal Metastasis
      $54,538
      award amount

  38. Reyan Coskun

    Leads 1 award · $54,538

    • 5F30HD115307-02Department: NIH department code
      Modeling the effects of the gut microbiota of undernourished mothers with environmental enteric dysfunction on vascular remodeling at the fetal-placental interface
      $54,538
      award amount

  39. Siling Du

    Leads 1 award · $51,038

    • 1F99AG095046-01Department: NIH department code
      Investigating the role of brain-engrafted monocyte-derived macrophages in Alzheimer's disease
      $51,038
      award amount

  40. Birk Evavold

    Leads 1 award · $36,673

    • 1F30AI188815-01A1Department: NIH department code
      Antibody feedback on B cell response to vaccination
      $36,673
      award amount

  41. Evan Matthew Lee

    Leads 1 award · $36,046

    • 1F30DK142304-01A1Department: NIH department code
      Identifying Prevotella copri-mediated effects of dietary glycan supplementation on microbial community and host metabolism
      $36,046
      award amount

  42. Jasmine Wright

    Leads 1 award · $36,046

    • 5F31AI183832-02Department: NIH department code
      Immunometabolic regulation of enteric viral infection
      $36,046
      award amount

  43. Rochelle Marie Ellison

    Leads 1 award · $36,046

    • 1F30CA298743-01Department: NIH department code
      Deciphering the immunomodulatory functions of phosphatidylserine in the tumor microenvironment
      $36,046
      award amount

  44. Maegan Murphy

    Leads 1 award · $35,490

    • 5F31AI174696-03Department: NIH department code
      Defining the regulation and regulatory mechanisms of TCF-1 in CD8+ T cell differentiation
      $35,490
      award amount

  45. Grace Uwase

    Leads 1 award · $35,187

    • 5F30AI181462-02Department: NIH department code
      Defining how ubiquitination of Ebola viral proteins affect host-viral dynamics
      $35,187
      award amount

  46. Saravanan Raju

    Leads 1 award · $1

    • 1K08AI187716-01Department: NIH department code
      Building an atlas of B cell mediated protective immunity to alphaviruses
      $1
      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.