Pathology at Washington University in St. Louis

Leads a grant in this department

38 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Amarasinghe, Gaya K.

   Leads 8 awards · $6,976,582

   • 2P01AI120943-06A1Department: NIH department code

     Molecular Mechanisms of Filoviral-host Interactions
     $3,354,992

     award amount
   • 1R01AI169850-01A1Department: NIH department code

     Characterizing the role of LDL related receptor 1 (Lrp1) as host entry factor for multiple bunyaviruses
     $783,556

     award amount
   • 5R01AI143292-05Department: NIH department code

     Novel VP30-host Interactions that Negatively Regulate Ebola Virus Infection
     $762,140

     award amount
   • 5R01AI161765-03Department: NIH department code

     Identification and Characterization of Entry Factors Critical for Rift Valley Fever Virus Infection and Pathogenesis
     $739,505

     award amount
   • 5R01AI161374-03Department: NIH department code

     Development and characterization of engineered therapeutic antibodies against SARS-CoV-2
     $638,713

     award amount
   • 3R01AI161374-03S1Department: NIH department code

     Development and characterization of engineered therapeutic antibodies against SARS-CoV-2
     $388,750

     award amount
   • 1R21AI176626-01A1Department: NIH department code

     HSP90 paralog selective small molecules as anti-old-world alpha-viral therapeutic leads.
     $247,725

     award amount
   • 3R01AI143292-05S1Department: NIH department code

     Novel VP30-host Interactions that Negatively Regulate Ebola Virus Infection
     $61,201

     award amount

2. Kipnis, Jonathan

   Leads 3 awards · $4,179,941

   • 5P01AG078106-02Department: NIH department code

     Neuroimmunology of AD and CAA with focus on innate immunity and lymphatics
     $3,063,305

     award amount
   • 5R01AG078667-02Department: NIH department code

     Aged T-cell-derived cytokines impact meningeal lymphatics and contribute to AD
     $579,380

     award amount
   • 5R37AG034113-14Department: NIH department code

     Immune system supports brain function
     $537,256

     award amount

3. Cicek, Mine

   Leads 1 award · $3,958,268

   • 5U24CA196171-09Department: NIH department code

     The Alliance NCTN Biorepository and Biospecimen Resource
     $3,958,268

     award amount

4. Randolph, Gwendalyn J

   Leads 6 awards · $3,135,659

   • 5DP1DK130660-03Department: NIH department code

     Defining the lymphatic basis of protein losing enteropathy after Fontan palliation or inflammatory gut disease
     $746,178

     award amount
   • 5R01AI168044-02Department: NIH department code

     Mechanisms that alter lymphatic transport in inflammatory bowel disease
     $564,050

     award amount
   • 5T32AI007163-45Department: NIH department code

     Training Program in Immunology
     $554,153

     award amount
   • 5U01AI163064-03Department: NIH department code

     Gut region-specific mechanisms that limit dissemination of microbial signals from the intestine
     $441,001

     award amount
   • 5R01DK119147-05Department: NIH department code

     Lymphatic remodeling and transport of dietary fats in short gut syndrome
     $436,527

     award amount
   • 5R37AI049653-23Department: NIH department code

     Differentiation and Function of Monocytes and Macrophages
     $393,750

     award amount

5. Colonna, Marco

   Leads 6 awards · $2,652,436

   • 1R01DK132327-01A1Department: NIH department code

     Mucosal Immune Defense Mechanisms of the Urinary Bladder
     $622,838

     award amount
   • 5R01AI158579-02Department: NIH department code

     Ontogenetic niche of B cells at the CNS borders in homeostasis, aging and autoimmunity
     $598,906

     award amount
   • 5R01CA262684-03Department: NIH department code

     Targeting TREM2 to boost anti-cancer therapy
     $432,265

     award amount
   • 5R01DK126969-03Department: NIH department code

     MICROBIOTA-DEPENDENT CONTROL OF CLOSTRIDIUM DIFFICILE: THE ROLE OF ACETATE AND IL-22 BINDING PROTEIN
     $410,302

     award amount
   • 5R01DK124699-04Department: NIH department code

     Plasticity of Innate Lymphoid Cells: Mechanisms and Biological Impact
     $354,375

     award amount
   • 5R21AI159210-02Department: NIH department code

     Impact of polyamines on ILC3 function at steady state and in preclinical model of colitis
     $233,750

     award amount

6. Corbo, Joseph

   Leads 4 awards · $2,464,604

   • 5R01HL149961-04Department: NIH department code

     High-throughput identification of causal variants underlying cardiac arrhythmia-related GWAS hits
     $720,789

     award amount
   • 5R01MH122451-04Department: NIH department code

     High-throughput identification of causal variants underlying neuropsychiatric disease-related GWAS hits
     $683,426

     award amount
   • 5R01EY030075-04Department: NIH department code

     Elucidating the cis-regulatory grammar of human photoreceptors
     $539,228

     award amount
   • 1R01EY033810-01A1Department: NIH department code

     Targeting Nr2e3 to prevent photoreceptor degeneration
     $521,161

     award amount

7. Choi, Kyunghee

   Leads 3 awards · $1,787,141

   • 5R01HL055337-26Department: NIH department code

     HEMANGIOBLAST DEVELOPMENT AND REGULATION
     $711,098

     award amount
   • 1R01CA271714-01A1Department: NIH department code

     Myct1 control of the angioimmune interface
     $559,360

     award amount
   • 5R01HL149954-04Department: NIH department code

     Epigenetic regulations of macrophage development
     $516,683

     award amount

8. Murphy, Kenneth M

   Leads 4 awards · $1,749,092

   • 5R01AI162643-02Department: NIH department code

     Molecular Basis of cDC1 Development
     $559,854

     award amount
   • 5R01AI150297-05Department: NIH department code

     Function of Wdfy4 in cross-presentation and immunity
     $489,211

     award amount
   • 5R01CA248919-03Department: NIH department code

     Understanding the Mechanisms of DC Licensing in CD8 T Cell Priming
     $466,777

     award amount
   • 5R21AI163421-02Department: NIH department code

     Transcriptional basis of embryonic macrophage development
     $233,250

     award amount

9. Dantas, Gautam

   Leads 2 awards · $1,469,535

   • 5R01AI155893-03Department: NIH department code

     Impact of early-life perturbations on pediatric microbiome maturation
     $776,694

     award amount
   • 5U01AI123394-08Department: NIH department code

     Structural, mechanistic, & evolutionary characterization of tetracycline destructases
     $692,841

     award amount

10. Liu, Ta-Chiang

    Leads 3 awards · $1,222,845

    • 1R01DK136829-01Department: NIH department code

      Dietary modulation of Paneth cells
      $506,884

      award amount
    • 5R01DK124274-04Department: NIH department code

      Paneth cell phenotype as a predictive biomarker for ulcerative colitis
      $361,586

      award amount
    • 5R01DK125296-04Department: NIH department code

      Cellular and molecular mechanisms of cigarette smoking-induced Paneth cell abnormality
      $354,375

      award amount

11. Wan, Xiaoxiao

    Leads 2 awards · $1,079,692

    • 1R01DK134437-01A1Department: NIH department code

      The role of beta-cell crinophagy in generating diabetogenic neoepitopes
      $611,651

      award amount
    • 5R01AI162591-02Department: NIH department code

      Autoimmune Diabetes: Macrophage Responses
      $468,041

      award amount

12. Gordon, Jeffrey I

    Leads 1 award · $1,037,721

    • 5R01DK131107-03Department: NIH department code

      The small intestinal microbiota in undernourished women and undernourished children in Bangladesh: identifying causal mechanisms and therapeutic targets
      $1,037,721

      award amount

13. Egawa, Takeshi

    Leads 4 awards · $1,022,323

    • 2R01AI130152-06A1Department: NIH department code

      The transcription factor c-MYC in lymphocyte expansion and restriction of stemness
      $565,821

      award amount
    • 1R56AI167361-01A1Department: NIH department code

      CD8 T cell fate decision instructed by IL-2
      $300,000

      award amount
    • 5R03AI166801-02Department: NIH department code

      Developing tools to study relationship between oxidative stress in T cell dysfunction
      $78,501

      award amount
    • 5R03AI166404-02Department: NIH department code

      Development of a novel mouse model with progesterone-independent susceptibility to genital HSV infection
      $78,001

      award amount

14. Edelson, Brian Todd

    Leads 2 awards · $826,726

    • 5R01AI162918-02Department: NIH department code

      Role of Intestinal Parasites on Regulating Immune Responses to Gut Antigens
      $631,726

      award amount
    • 5R21AI168706-02Department: NIH department code

      Selective induction of alloantigen-specific humoral tolerance by MHC-Fc fusion proteins
      $195,000

      award amount

15. Kim, Brian

    Leads 1 award · $824,258

    • 1R01AI176660-01Department: NIH department code

      Defining the role of IL-18 in atopic dermatitis
      $824,258

      award amount

16. Klechevsky, Eynav Yafit

    Leads 2 awards · $699,576

    • 5R01CA245277-04Department: NIH department code

      The Role of CD5 in Tumor Immunity
      $353,076

      award amount
    • 5R01AR075959-05Department: NIH department code

      Harnessing Human Dendritic Cell Subsets in Skin for the Design of Novel Immunotherapies
      $346,500

      award amount

17. Ellebedy, Ali Hassan

    Leads 1 award · $654,858

    • 5U01AI141990-05Department: NIH department code

      Programming Durable Immune Responses To Vaccination
      $654,858

      award amount

18. Van Dyken, Steven

    Leads 2 awards · $616,364

    • 5R01HL148033-04Department: NIH department code

      Targeting chitin in fibrotic lung disease
      $421,780

      award amount
    • 1R21AI163640-01A1Department: NIH department code

      Chitin and chitinases in SARS-CoV-2 infection
      $194,584

      award amount

19. Ravichandran, Kodi S

    Leads 1 award · $580,025

    • 5R01AI159551-04Department: NIH department code

      Solute carrier proteins in efferocytosis and inflammation
      $580,025

      award amount

20. Teitelbaum, Steven L

    Leads 1 award · $470,750

    • 5R01CA258325-02Department: NIH department code

      Hepatic steatosis promotes liver metastasis
      $470,750

      award amount

21. Brestoff, Jonathan R

    Leads 1 award · $393,750

    • 5DP5OD028125-05Department: NIH department code

      Regulation of innate immune cell responses through cell-to-cell transfer of mitochondria
      $393,750

      award amount

22. Grajales-Reyes, Gary E.

    Leads 1 award · $388,750

    • 5DP5OD033428-02Department: NIH department code

      CAR-based approaches for the treatment of Alzheimer's Disease
      $388,750

      award amount

23. Duncavage, Eric J

    Leads 1 award · $388,026

    • 1R33CA278510-01Department: NIH department code

      A Rapid and Comprehensive Approach for Clinical Genomic Profiling in Lung Cancer
      $388,026

      award amount

24. Schreiber, Robert David

    Leads 1 award · $379,475

    • 5T32CA009547-37Department: NIH department code

      TRAINING IN THE IMMUNOBIOLOGY AND MOLECULAR CELL BIOLOGY OF CANCER
      $379,475

      award amount

25. Miller, Grover P

    Leads 1 award · $369,432

    • 5R01GM140635-04Department: NIH department code

      Systematic Discovery of Bioactivation-Associated Structural Alerts
      $369,432

      award amount

26. Mosammaparast, Nima

    Leads 1 award · $366,581

    • 5R01CA193318-09Department: NIH department code

      Damaged RNA as a mediator of alkylation responses
      $366,581

      award amount

27. Ackerman, Sarah D

    Leads 1 award · $249,000

    • 4R00NS121137-03Department: NIH department code

      The role of astrocyte-neuron signaling in closing a critical period required for motor circuit structure function and behavior
      $249,000

      award amount

28. Wang, Yi

    Leads 1 award · $143,929

    • 1K01DK134840-01Department: NIH department code

      Key gut microbes shape intestinal epithelial lineage development, differentiation and metabolic function
      $143,929

      award amount

29. Han, Jichang

    Leads 1 award · $92,123

    • 5K00CA264434-03Department: NIH department code

      Deciphering the role of tumor-macrophage crosstalk during metastatic dissemination to the peritoneum
      $92,123

      award amount

30. Diorio-Toth, Luke Evan

    Leads 1 award · $52,694

    • 5F30AI157161-03Department: NIH department code

      Mapping the evolutionary landscape of a novel family of tetracycline resistance enzymes
      $52,694

      award amount

31. Mintz, Rachel

    Leads 1 award · $52,694

    • 1F30CA281124-01Department: NIH department code

      Mechanisms Underlying the Omental Support of Ovarian Cancer Peritoneal Metastasis
      $52,694

      award amount

32. Wu, Renee Paula

    Leads 1 award · $52,694

    • 5F30CA247262-03Department: NIH department code

      The role of type 1 dendritic cells in CD4 and CD8 T cell anti-tumor immunity
      $52,694

      award amount

33. Kao, Clara

    Leads 1 award · $51,630

    • 5F30DK132805-02Department: NIH department code

      CHARACTERIZATION OF THE ROLE OF THE SMALL INTESTINAL MICROBIOTA IN THE PATHOGENESIS OF ENVIRONMENTAL ENTERIC DYSFUNCTION IN UNDERNOURISHED CHILDREN AND MOTHERS
      $51,630

      award amount

34. Zhou, Cyrus

    Leads 1 award · $51,630

    • 5F30DK131866-02Department: NIH department code

      Mechanism of action of a microbiota-directed complementary food that promotes ponderal growth in Bangladeshi children with moderate acute malnutrition
      $51,630

      award amount

35. Kelley, Shannon

    Leads 1 award · $36,450

    • 5F31HL160134-04Department: NIH department code

      Testing the tyrosine phosphatase SHP-2 as a novel brake on efferocytosis
      $36,450

      award amount

36. Chen, Jing

    Leads 1 award · $33,646

    • 1F30HL167565-01Department: NIH department code

      The role of EMT transcription factor Zeb2 in fetal hematopoiesis
      $33,646

      award amount

37. Murphy, Maegan

    Leads 1 award · $33,646

    • 1F31AI174696-01Department: NIH department code

      Defining the regulation and regulatory mechanisms of TCF-1 in CD8+ T cell differentiation
      $33,646

      award amount

38. Mazzitelli Perez, Jose Alejandro

    Leads 1 award · $33,343

    • 1F30HD112122-01A1Department: NIH department code

      The role of skull bone marrow-derived CNS macrophages in Rett syndrome.
      $33,343

      award amount