Startle Amplitude
Peak whole-body startle response magnitude to the pulse stimulus
ConductVision · Behavioral Analysis
Prepulse Inhibition (PPI)
Quantify sensorimotor gating by measuring startle response modulation.
RodentSensorimotor GatingAuto Export
ConductVision / Prepulse Inhibition (PPI)
Recording / Trial 3subject tracked
Startle Amplitudelive
% PPIauto
Startle Latency7.2s
Key Parameters
Metrics automatically extracted by ConductVision.
% PPI
Percentage reduction in startle when preceded by a prepulse
Startle Latency
Time from pulse onset to peak startle response
Prepulse Intensity Curve
PPI across multiple prepulse dB levels (e.g., 74, 78, 82, 86 dB)
Habituation Index
Startle amplitude decline across repeated pulse-alone trials
No-Stimulus Baseline
Background movement during null trials for noise floor calibration
What is Prepulse Inhibition?
Prepulse inhibition is a neurological phenomenon in which a weak sensory stimulus (prepulse) attenuates the startle response to a subsequent strong stimulus (pulse). PPI deficits are a translational biomarker for schizophrenia, autism spectrum disorder, and other neuropsychiatric conditions involving impaired sensorimotor gating.
ConductVision integrates with startle response hardware to capture high-resolution force-plate or accelerometer data. The software automates trial randomization, calculates percent PPI across prepulse intensities, tracks habituation curves, and exports publication-ready dose-response plots.
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