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68 results for “Vernonia”
Fig. 3 in Phytoconstituents from Vernonia glaberrima Welw. Ex O. Hoffm. leaves and their cytotoxic activities on a panel of human cancer cell lines
Fig. 3. Effect of Vernonia glaberrima leaves crude methanolic extract on cancer cells viability as determined by MTS assay.
Fig. 10. Compounds 1–8 in Bisabolane-type sesquiterpenes from Vernonia amygdalina: Absolute configuration and anti-inflammatory activity
Fig. 10. Compounds 1–8 inhibited the activation of PI3K/AKT signaling pathways in LPS-induced RAW 264.7 cells. A: The expression of relative proteins related to the PI3K/AKT signaling pathways involved inflammation, including PI3K, NF-κB (p65), and AKT RAW 264.7 cells. B–D: The relative levels of p-PI3K/PI3K, p-AKT/ AKT, and p-p65/p65 were quantified (mean ± SD. ###p <0.001, compared with the group untreated with LPS; *p <0.05, **p <0.01 and ***p <0.001 compared with the group treated with LPS.).
Fig. 5. A in Bisabolane-type sesquiterpenes from Vernonia amygdalina: Absolute configuration and anti-inflammatory activity
Fig. 5. A: Analysis of modified Mosher's method for 1. Δδ values (in ppm) = δS MTPA esters (1a) and (R)-MTPA esters (1b) at H-12.
Fig. 9 in Bisabolane-type sesquiterpenes from Vernonia amygdalina: Absolute configuration and anti-inflammatory activity
Fig. 9. Effects of Compounds 1–8 on the NO production and the expression of iNOS and COX-2 proteins. RAW 264.7 cells were pretreated with Compounds 1–8 for 2 h and then stimulated with 1 μg/mL LPS for additional 24 h. A: The effect of Compounds 1–8 on the viability of RAW 264.7 cells. B: The inhibitory effect of Compounds 1–8 on LPS-induced NO production in RAW 264.7 cells. C: Western blot of the expression levels of iNOS and COX-2 proteins. D–E: Quantitative densitometry analysis of iNOS/β-actin and COX-2/β-actin (mean ± SD. ###p <0.001, compared with the group untreated with LPS; *p <0.05, **p <0.01 and ***p <0.001 compared with the group treated with LPS.).
Fig. 8. A in Bisabolane-type sesquiterpenes from Vernonia amygdalina: Absolute configuration and anti-inflammatory activity
Fig. 8. A: Regression analysis of experimental vs. calculated 13C NMR chemical shifts of (6R, 7S, 11R)-8; B: DP4 probability analysis for (6R*, R*, 11R*)-8 (6R*, + 7, 7R*, 11S*)-8, (6R*, 7S*, 11R*)-8 and (6R*, 7S*, 11S*)-8 at the PCM-mPW1PW91/6-31G (d, p) level.
Fig. 7. A in Bisabolane-type sesquiterpenes from Vernonia amygdalina: Absolute configuration and anti-inflammatory activity
Fig. 7. A: Experimental circular dichroism spectrum of the in situ formed Mo2(OAc)4-complex of Compound 7; B: Conformational analysis of the Mo complex of 7. The active Cotton effect of the complex at 301 nm suggests that the favoured conformation is the S-configuration at C-2′.
Vernonia gigantea (Asteraceae) - inflorescence - whole - unspecified
Image of Vernonia gigantea (Asteraceae) - inflorescence - whole - unspecified
Figure 2 from: Robinson H, Funk VA (2018) Vernonia subgenus Austrovernonia, a new subgenus from South America (Compositae, Vernonieae, Vernoniinae). PhytoKeys 110: 123-134. https://doi.org/10.3897/phytokeys.110.28890
Figure 2 Phylogeny with an indication of where Vernoniaincana Less. is placed (arrow). The phylogeny is modified from Keeley et al. 2017 and does not take into account all the taxa that were in the analysis performed by the authors using data from Keeley et al. (in prep.).
Figure 1 from: Robinson H, Funk VA (2018) Vernonia subgenus Austrovernonia, a new subgenus from South America (Compositae, Vernonieae, Vernoniinae). PhytoKeys 110: 123-134. https://doi.org/10.3897/phytokeys.110.28890
Figure 1 Habitat of Vernoniaincana and V.echioides taken with a drone at the Environmental Protection Area Rincon de Franquía, Cuareim River, Artigas, Uruguay: insert shows in red the areas where the semi-aquatic Vernonias of South America can be found. (photos by J.M. Bonifacino, MVFA).
Figure 4 from: Robinson H, Funk VA (2018) Vernonia subgenus Austrovernonia, a new subgenus from South America (Compositae, Vernonieae, Vernoniinae). PhytoKeys 110: 123-134. https://doi.org/10.3897/phytokeys.110.28890
Figure 4 Image of the selected lectotype for Vernoniaincana Less. There are now six isosyntypes in European herbaria: all the specimens are similar, but the LL specimen was selected as the lectotype because it had the most complete information, including the collecting number and the label indicates that it had been in the Berlin herbarium before it was sent to S.F. Blake. [photo courtesy of JSTOR-Plants, continuously updated].
Figure 3 from: Robinson H, Funk VA (2018) Vernonia subgenus Austrovernonia, a new subgenus from South America (Compositae, Vernonieae, Vernoniinae). PhytoKeys 110: 123-134. https://doi.org/10.3897/phytokeys.110.28890
Figure 3 Image of US herbarium sheet of Vernoniaincana Less. which shows the two types of roots: fleshy and fibrous. [photo courtesy of I. Lin, US].
FIGURE 2 in A new species of Vernonia (Asteraceae, Vernonieae) from the state of Oaxaca, Mexico
FIGURE 2. Holotype of Vernonia confusa, specimen housed at Herbario Nacional de Mexico (MEXU).
FIGURE 4 in A new species of Vernonia (Asteraceae, Vernonieae) from the state of Oaxaca, Mexico
FIGURE 4. Distribution map of Vernonia confusa in the state of Oaxaca, México.
Table 1 in Phytoconstituents from Vernonia glaberrima Welw. Ex O. Hoffm. leaves and their cytotoxic activities on a panel of human cancer cell lines
<p><b>Table 1</b> The IC 50 values for the cytotoxic activity of <i>Vernonia glaberrima</i> leaves crude methanolic extract on cancer cell lines for 72-h treatment.</p><table><tbody><tr><th>Cancer cell lines</th><th>IC50 (μg/mL)</th></tr></tbody><tbody><tr><th>A375</th><td>26.23 (1.14)</td></tr><tr><th>HT-29</th><td>101.92 (7.86)</td></tr><tr><th>MCF7</th><td>206.60 (12.72)</td></tr></tbody></table><p>The values are means with SD in parenthesis for three replicates.</p>
Table 2 in Phytoconstituents from Vernonia glaberrima Welw. Ex O. Hoffm. leaves and their cytotoxic activities on a panel of human cancer cell lines
<p><b>Table 2</b> IC 50 values for 72-h treatment with <i>V. glaberrima</i> compounds on different cell lines.</p><table><tbody><tr><th>Treatment</th><th>IC50 (μg/mL)</th></tr></tbody><tbody><tr><th></th><td>A375</td><td>HT-29</td><td>MCF7</td></tr><tr><th>Nonacosanoic acid (1)</th><td>ND</td><td>ND</td><td>ND</td></tr><tr><th>Lupeol (2)</th><td>59.18 (2.70)</td><td>15.24 (1.15)</td><td>34.15 (2.32)</td></tr><tr><th>5-Methylcoumarin-4-β- glucoside (3)</th><td>91.84 (6.78)</td><td>20.00 (1.60)</td><td>ND</td></tr><tr><th>4-Hydroxy-5-methylcoumarin (4)</th><td>139.53 (10.79)</td><td>4.22 (0.13)</td><td>ND</td></tr><tr><th>5-Fluorouracil</th><td>3.91 (0.25)</td><td>8.00 (0.78)</td><td>4.33 (0.11)</td></tr></tbody></table><p>The values represent means obtained results of triplicate experiments with SD in parenthesis, ND depicts no detected activity.</p>
Figure 1 from: Robinson H, Yankowski S (2016) The Taxonomic Significance of ducts in the corolla lobes of Vernonia (Vernonieae: Asteraceae). PhytoKeys 58: 1-7. https://doi.org/10.3897/phytokeys.58.7009
Figure 1 - A–D: A, B, Vernonia noveboracensis cross-sections of corolla lobes, outer surface upward C longitudinal section of corolla lobe showing multiple ducts D corolla lobe from specimen in preservative showing only poorly defined partitions between ducts E Vernonia angustifolia, corolla lobe from freshly collected specimen showing fresh resin in ducts F Vernonanthura brasiliana, corolla lobe from dried herbarium specimen showing solidified contents of ducts with walls over-lying cell layer G Vernonia echioides, part of corolla lobe from dried herbarium specimen showing some short-stalked capitate glands H Vernonia incana, part of corolla lobe from dried herbarium specimen.
Fig. 6 in Bisabolane-type sesquiterpenes from Vernonia amygdalina: Absolute configuration and anti-inflammatory activity
Fig. 6. Experimental and calculated ECD spectra of (A) 7′ and (B) 8.
Fig. 2. Key 2D in Bisabolane-type sesquiterpenes from Vernonia amygdalina: Absolute configuration and anti-inflammatory activity
Fig. 2. Key 2D NMR correlations of 1, 3, 5 and 7.
Fig. 3 in Bisabolane-type sesquiterpenes from Vernonia amygdalina: Absolute configuration and anti-inflammatory activity
Fig. 3. Key NOESY correlations of 1, 3, 5 and 7.
Fig. 4 in Bisabolane-type sesquiterpenes from Vernonia amygdalina: Absolute configuration and anti-inflammatory activity
Fig. 4. Relative configuration analysis of the C6–C7 segment in 1, 3, 5 and 7 by Newman projection.
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