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819 results for “Gender;”
Estrogen-independent Epigenetic Mechanisms Regulate Gender Dimorphisms in Cardiac Reparative Functions of Bone Marrow Progenitor Cells
GEO Series GSE253058. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
ORCA. IT: a new web-based tool for assessing online reading search and comprehension abilities in students reveals effects of gender, school type and reading ability. Frontiers in psychology, 10, 2433.
<p>Dataset containing the raw scores of the participants described in the paper "ORCA. IT: a new web-based tool for assessing online reading search and comprehension abilities in students reveals effects of gender, school type and reading ability", published in <em>Frontiers in Psychology</em>, <em>10</em>, 2433.</p>
Data set from Ranucci M, de Vincentiis C, Menicanti L, La Rovere MT, Pistuddi V. A gender-based analysis of the obesity paradox in cardiac surgery: height for women, weight for men? Eur J Cardiothorac Surg. 2019 Jul 1;56(1):72-78. doi: 10.1093/ejcts/ezy454. PMID: 30657927.
<p>Data set from Ranucci M, de Vincentiis C, Menicanti L, La Rovere MT, Pistuddi V. A gender-based analysis of the obesity paradox in cardiac surgery: height for women, weight for men? Eur J Cardiothorac Surg. 2019 Jul 1;56(1):72-78. doi: 10.1093/ejcts/ezy454. PMID: 30657927.</p> <p> </p> <p>This is the abstract:</p> <p><strong>Objectives: </strong> In cardiac surgery, obesity is associated with a lower mortality risk. This study aims to investigate the association between body mass index (BMI) and operative mortality separately in female patients and male patients undergoing cardiac surgery and to separate the effects of weight and height in each gender-based cohort of patients.</p> <p><strong>Methods: </strong> A retrospective cohort study including 7939 consecutive patients who underwent cardiac surgery was conducted. The outcome measure was the operative mortality.</p> <p><strong>Results: </strong> In men, there was a U-shaped relationship between the BMI and the operative mortality, with the lower mortality rate at a BMI of 35 kg/m2. In women, the relationship is J-shaped, with the lower mortality at a BMI of 22 kg/m2. Female patients with obesity class II-III had a relative risk for operative mortality of 2.6 [95% confidence interval (CI) 1.37-4.81, P = 0.002]. The relationship between weight and mortality rate is a U-shaped bot in men and women, with the lower mortality rate at 100 kg for men and 70 kg for women. Height was linearly and inversely associated with the operative mortality in men and women. After correction for the potential confounders, height, but not weight, was independently associated with operative mortality in women (odds ratio 0.949, 95% CI 0.915-0.983; P = 0.004); conversely, in men, this association exists for weight (odds ratio 1.017, 95% CI 1.001-1.032; P = 0.034), but not height.</p> <p><strong>Conclusions: </strong> Contrary to men, in women obesity does not reduce the operative mortality in cardiac surgery, whereas the height seems to be associated with a lower mortality.</p>
Mortality in an Italian nursing home during COVID-19 pandemic: correlation with gender, age, ADL, vitamin D supplementation, and limitations of the diagnostic tests
<p><strong>Introduction: </strong> The COVID-19 pandemic caused an increased mortality in nursing homes due to its quick spread and the age-related high lethality.</p> <p><strong>Results: </strong> We observed a two-month mortality of 40%, compared to 6.4% in the previous year. This increase was seen in both COVID-19 positive (43%) and negative (24%) residents, but 8 patients among those testing negative on the swab, tested positive on serological tests. Increased mortality was associated with male gender, older age, no previous vitamin D supplementation and worse "activities of daily living (ADL)" scores, such as Barthel index, Tinetti scale and S.OS.I.A.</p> <p><strong>Conclusion: </strong> Our data confirms a higher geriatric mortality due to COVID-19. Negative residents also had higher mortality, which we suspect is secondary to preanalytical error and a low sensitivity of the swab test in poorly compliant subjects. Male gender, older age and low scores on ADL scales (probably due to immobility) are risk factors for COVID-19 related mortality. Finally, mortality was inversely associated with vitamin D supplementation.</p> <p><strong>Design: </strong> In this observational study, we described the two-month mortality among the 157 residents (age 60-100) of a nursing home after Sars-CoV-2 spreading, reporting the factors associated with the outcome. We also compared the diagnostic tests for Sars-CoV-2.</p> <p> </p><p>https://pubmed.ncbi.nlm.nih.gov/33353888/</p> <p></p>
HBSC Data: Exercise and Eating Behaviors in Transgender and Gender Diverse Adolescents
Open the record for dataset details and reuse information.
dataset relate to article "Adults with spinal muscular atrophy a large-scale natural history study shows gender effect on disease"
<p>Dataset contains clinical anonymized data of patients involved in study mentioned at title</p>
Data set related to the article: "Gender Differences Associated with the Prognostic Value of BPIFB4 in COVID-19 Patients: A Single-Center Preliminary Study."
<p><strong>Abstract:</strong> In the ongoing global COVID-19 pandemic, male sex is a risk factor for severe disease and death, and the reasons for these clinical discrepancies are largely unknown. The aim of this work is to study the influence of sex on the course of infection and the differences in prognostic markers between genders in COVID-19 patients. Our cohort consisted of 64 adult patients (n = 34 men and n = 30 women) with PCR-proven SARS-CoV-2 infection. Further, a group of patients was characterized by a different severity degree (n = 8 high- and n = 8 low-grade individuals for both male and female patients). As expected, the serum concentrations of LDH, fibrinogen, CRP, and leucocyte count in men were significantly higher than in females. When serum concentrations of the inflammatory cytokines, including IL-6, IL-2, IP-10 and IL-4 and chemokines like MCP-1, were measured with multiplex ELISA, no significant differences between male and female patients were found. In COVID-19 patients, we recently attributed a new prognostic value to BPIFB4, a natural defensin against dysregulation of the immune responses. Here, we clarify that BPIFB4 is inversely related to the disease degree in men but not in women. Indeed, higher levels of BPIFB4 characterized low-grade male patients compared to high-grade ones. On the contrary, no significant difference was reported between low-grade female patients and high-grade ones. In conclusion, the identification of BPIFB4 as a biomarker of mild/moderate disease and its sex-specific activity would open an interesting field for research to underpin gender-related susceptibility to the disease.</p>
Dataset related to: "Gender and Age as Determinants of Success of Pulmonary Rehabilitation in Individuals With Chronic Obstructive Pulmonary Disease"
<p>We provide the raw data used for the following scientific letter:</p> <p>Maestri R, Vitacca M, Paneroni M, Zampogna E, Ambrosino N. <strong>Gender and Age as Determinants of Success of Pulmonary Rehabilitation in Individuals With Chronic Obstructive Pulmonary Disease.</strong> Arch Bronconeumol. 2023 Mar;59(3):174-177. English, Spanish. doi: 10.1016/j.arbres.2022.09.008.</p> <p><em>No abstract available</em></p>
Characteristics, medical management, and outcomes of survivors of gender-based violence in Neno, Malawi
<p>This dataset is for gender-based violence (GBV) records; collected from GBV registers across health facilities in Neno, Malawi.</p>
gene expression in monkey aorta with aging and gender
GEO Series GSE6599. Homo sapiens; Macaca fascicularis. 24 samples. Type: Expression profiling by array.
Estrogen-independent Epigenetic Mechanisms Regulate Gender Dimorphisms in Cardiac Reparative Functions of Bone Marrow Progenitor Cells [Cut & Tag]
GEO Series GSE253057. Mus musculus. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Data set from Ranucci M, Aloisio T, Di Dedda U, Menicanti L, de Vincentiis C, Baryshnikova E; Surgical and Clinical Outcome REsearch (SCORE) group. Gender-based differences in platelet function and platelet reactivity to P2Y12 inhibitors. PLoS One. 2019 Nov 27;14(11):e0225771. doi: 10.1371/journal.pone.0225771. PMID: 31774869; PMCID: PMC6881030.
<p>Data set from Ranucci M, Aloisio T, Di Dedda U, Menicanti L, de Vincentiis C, Baryshnikova E; Surgical and Clinical Outcome REsearch (SCORE) group. Gender-based differences in platelet function and platelet reactivity to P2Y12 inhibitors. PLoS One. 2019 Nov 27;14(11):e0225771. doi: 10.1371/journal.pone.0225771. PMID: 31774869; PMCID: PMC6881030.</p> <p>This is the article:</p> <p><strong>Background: </strong> Gender influences platelet biology. Women have a larger platelet count, but gender-based differences in platelet function remain debated. We performed a study addressing gender-based differences in platelet function using point-of-care platelet function tests (PFT).</p> <p><strong>Methods: </strong> The patient population consisted of 760 cardiac surgery patients where preoperative PFT (multiple-electrode aggregometry [MEA]) were available. Platelet count and function at the ADPtest and TRAPtest were compared in the overall population and separately in patients with or without residual effects of P2Y12 inhibitors.</p> <p><strong>Results: </strong> Women had a significantly (P = 0.001) higher platelet count but a non-significantly higher platelet reactivity to ADP. In clopidogrel-treated patients, the platelets ADP reactivity was significantly (P = 0.031) higher in women, and platelet count was the main determinant of platelet hyper-reactivity. Within patients under full clopidogrel effects, women with a platelet count ≥ 200,000 cells/μL had a significantly (P = 0.023) higher rate of high-on-treatment platelet reactivity (HTPR, 45.5%) with respect to males with a platelet count < 200,000 cells/μL (11.9%), with a relative risk of 6.2 (95% confidence interval 1.4-29).</p> <p><strong>Conclusions: </strong> Our findings confirm that women have a larger platelet count than men, and that this is associated to a trend towards a higher platelet reactivity. HTPR is largely represented in women with a high platelet count. This generates the hypothesis that women requiring P2Y12 inhibitors could potentially benefit from larger doses of drug or should be treated with anti-platelet agents with a low rate of HTPR.</p>
Gender and age normalization and ventilation efficiency during exercise in heart failure with reduced ejection fraction.
<p>Raw data of the manuscript "Gender and age normalization and ventilation efficiency during exercise in heart failure with reduced ejection fraction."</p> <p> </p> <p><strong>Aims: </strong>Ventilation vs. carbon dioxide production (VE/VCO<sub>2</sub> ) is among the strongest cardiopulmonary exercise testing prognostic parameters in heart failure (HF). It is usually reported as an absolute value. The current definition of normal VE/VCO<sub>2</sub> slope values is inadequate, since it was built from small groups of subjects with a particularly limited number of women and elderly. We aimed to define VE/VCO<sub>2</sub> slope prediction formulas in a sizable population and to test whether the prognostic power of VE/VCO<sub>2</sub> slope in HF was different if expressed as a percentage of the predicted value or as an absolute value.</p> <p><strong>Methods and results: </strong>We calculated the linear regressions between age and VE/VCO<sub>2</sub> slope in 1136 healthy subjects (68% male, age 44.9 ± 14.5, range 13-83 years). We then applied age-adjusted and sex-adjusted formulas to predict VE/VCO<sub>2</sub> slope to HF patients included in the metabolic exercise test data combined with cardiac and kidney indexes score database, which counts 6112 patients (82% male, age 61.4 ± 12.8, left ventricular ejection fraction 33.2 ± 10.5%, peakVO<sub>2</sub> 14.8 ± 4.9, mL/min/kg, VE/VCO<sub>2</sub> slope 32.7 ± 7.7) from 24 HF centres. Finally, we evaluated whether the use of absolute values vs. percentages of predicted VE/VCO<sub>2</sub> affected HF prognosis prediction (composite of cardiovascular mortality + urgent transplant or left ventricular assist device). We did so in the entire cardiac and kidney indexes score population and separately in HF patients with severe (peakVO<sub>2</sub> < 14 mL/min/kg, n = 2919, 61.1 events/1000 pts/year) or moderate (peakVO<sub>2</sub> ≥ 14 mL/min/kg, n = 3183, 19.9 events/1000 pts/year) HF. In the healthy population, we obtained the following equations: female, VE/VCO<sub>2</sub> = 0.052 × Age + 23.808 (r = 0.192); male, VE/VCO<sub>2</sub> = 0.095 × Age + 20.227 (r = 0.371) (P = 0.007). We applied these formulas to calculate the percentages of predicted VE/VCO<sub>2</sub> values. The 2-year survival prognostic power of VE/VCO<sub>2</sub> slope was strong, and it was similar if expressed as absolute value or as a percentage of predicted value (AUCs 0.686 and 0.690, respectively). In contrast, in severe HF patients, AUCs significantly differed between absolute values (0.637) and percentages of predicted values (0.650, P = 0.0026). Moreover, VE/VCO<sub>2</sub> slope expressed as a percentage of predicted value allowed to reclassify 6.6% of peakVO<sub>2</sub> < 14 mL/min/kg patients (net reclassification improvement = 0.066, P = 0.0015).</p> <p><strong>Conclusions: </strong>The percentage of predicted VE/VCO<sub>2</sub> slope value strengthens the prognostic power of VE/VCO<sub>2</sub> in severe HF patients, and it should be preferred over the absolute value for HF prognostication. Furthermore, the widespread use of VE/VCO<sub>2</sub> slope expressed as percentage of predicted value can improve our ability to identify HF patients at high risk, which is a goal of utmost clinical relevance.</p>
Narratives of Girls and Boys with Autism Spectrum Disorders: Gender Differences in Narrative Competence and Internal State Language
<p>Data set of Kauschke, C., van der Beek, B., & Kamp-Becker, I. (2016). Narratives of girls and boys with autism spectrum disorders: Gender differences in narrative competence and Internal State Language.<em> Journal of Autism and Developmental Disorders</em>, 46(3), 840-853. doi: 10.1007/s10803-015-2620-5.</p> <p>Data on request.</p>
Perception biases of gender in political talk shows? A Twitter analysis of user engagement in Germany
<p><strong>Perception biases of gender in political talk shows?</strong></p> <p>This dataset contains the raw and processed data analysed in the CSS lecture at TUM. </p> <p> </p> <p><strong>Explanation</strong></p> <ul> <li>raw.zip: Contains the raw data structured by year it was created</li> <li>annotated_data.json: data as it was used for the analysis after filtering and combining with participant data</li> <li>participant_encoding.csv: encoded information about participants of talk shows</li> </ul>
How do table shape, group size, and gender affect on-task actions in computer education open-ended tasks_data
<p>The data set includes the coding scheme, results of intercoder reliability tests and results of statistical tests supporting the paper " How do table shape, group size, and gender affect on-task actions in computer education open-ended tasks "</p>
DIAPASON Project: Therapeutic alliance and gender: an analysis of DIAPASON data
<p>Dataset of the paper entitled <em>Therapeutic alliance and gender: an analysis of DIAPASON data.</em> of the project "DAILY TIME USE, PHYSICAL ACTIVITY, QUALITY OF CARE AND INTERPERSONAL RELATIONSHIPS IN PSYCHIATRIC RESIDENTIAL FACILITIES: AN ITALIAN MULTICENTRE STUDY" Italian Ministry of Health, Italy, Ricerca Finalizzata (Grant RF-<a>2018-12365514</a>) (https://www.diapason-study.eu/)</p>
Effects of Interpersonal Sensorimotor Synchronization on Dyadic Creativity: Gender Matters
<p>Effects of Interpersonal Sensorimotor Synchronization on Dyadic Creativity: Gender Matters</p>
Gender-Affirming Care and Mental Health
ClinicalTrials.gov study NCT07171645. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.