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2,937 results for “Multiple Myeloma”
Super-enhancer-driven PPP1R15B/CReP, regulated by C/EBPβ and YY1, is oncogenic in multiple myeloma
GEO Series GSE267004. Homo sapiens. 16 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other.
Amiloride, an old diuretic drug, is a potential therapeutic agent for multiple myeloma
GEO Series GSE95077. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Che-1/miR-590-3p/TAZ axis sustains multiple myeloma disease
GEO Series GSE234642. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
A Phase II Study of Pomalidomide, Daily Low Dose Oral Cyclophosphamide, and Dexamethasone in Relapsed/Refractory Multiple Myeloma
GEO Series GSE138717. Homo sapiens. 17 samples. Type: Expression profiling by high throughput sequencing.
scCNVseq Datasets Supporting Tumor Intrinsic Mechanisms of Antigen Escape to Anti-BCMA and Anti-GPRC5D Targeted Immunotherapies in Multiple Myeloma
GEO Series GSE226327. Homo sapiens. 37 samples. Type: Other.
Identification of aberrant miRNA expression in multiple myeloma
GEO Series GSE73048. Homo sapiens. 30 samples. Type: Non-coding RNA profiling by array.
Identification of heterogeneous networks and plasma-monocytes crosstalks in multiple myeloma stratified by R-ISS system through single-cell sequencing
GEO Series GSE176131. Homo sapiens. 11 samples. Type: Expression profiling by high throughput sequencing.
p300 catalytic inhibition selectively targets IRF4 oncogenic activity in multiple myeloma (RPMI8226_KB528_timeseries)
GEO Series GSE274845. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
p300 catalytic inhibition selectively targets IRF4 oncogenic activity in multiple myeloma (PBMC_KB528_timeseries)
GEO Series GSE274843. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Supplementary material from: A 59-year-old woman with multiple myeloma and lower extremity weakness and numbness
<p>Supplementary Table 1. Upper motor neuron (UMN) vs. lower motor neuron (LMN) syndromes.</p>
Hallmarks of T-cell exhaustion and antigen experience are absent in multiple myeloma from diagnosis to maintenance therapy
<p>Code and data associated with Shasha et al., "Hallmarks of T-cell exhaustion and antigen experience are absent in multiple myeloma from diagnosis to maintenance therapy" (<a href="https://doi.org/10.1182/blood.2024025655" target="_blank" rel="noopener">https://doi.org/10.1182/blood.2024025655</a>). Description of files below:</p> <p>scRNA-seq_code.tar: Python notebooks for analysis of scRNA-seq data, including import and figure generation</p> <p>adata-rev.h5ad: processed CD8 T cell scRNA-seq data from all patients and samples combined. Includes condensed TCR info (refer to columns 'cdr3' for example; 'chain_id' was determined per batch and can be ignored)</p> <p>ics_tsv_repeat_dat.csv: ICS metadata</p> <p>cytof_ics_repeat_data.tar: normalized ICS tsv and fcs files from all patients and samples</p> <p>ics_repeat_analysis.R: R code for analysis of ICS data</p> <p>cytof_data.tar: CyTOF fcs and txt files (bead normalized and compensated, gated to CD8 T cells)</p> <p> </p>
A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma
<p>This repository contains R Seurat objects associated with our study titled "<strong>A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma</strong>". </p> <p>This repository contains two Seurat objects stored in .rds files containing processed single-cell RNA sequencing data from the original ‘Discovery’ cohort of the MMRF Immune Atlas study, along with an additional ‘Discovery + Validation’ cohort, as described in the original publication. These .rds files contain Seurat v4 objects with basic cell type annotation and qc metadata. Specific file contents will be detailed below.</p> <div> <p>A copy of the ‘Cell Annotation Dictionary’ is also included, which contains additional details on the individual annotated clusters in the Immune Atlas dataset.</p> <p>Information on how to request additional metadata about these samples and accessing the original fastq files will be detailed at the end of this description</p> </div>
Stem Cell Translpantation in Multiple Myeloma
ClinicalTrials.gov study NCT05082675. IPD Sharing: Not stated. Countries: 11. Publications: 0.
BB-10901 in Treating Patients With Relapsed and/or Refractory Multiple Myeloma
ClinicalTrials.gov study NCT00346255. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Novel Drugs After Allo-HSCT in Patients With Multiple Myeloma
ClinicalTrials.gov study NCT04506320. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study of DeepTag-GPRC5D Targeted CAR-T Cells Therapy for Refractory/Relapsed Multiple Myeloma
ClinicalTrials.gov study NCT06084962. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Combination of Zarnestra With Velcade for Patients With Relapsed Multiple Myeloma
ClinicalTrials.gov study NCT00361088. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Safety and Efficacy of BCMA-Targeted CAR-T Therapy for Relapsed/Refractory Multiple Myeloma
ClinicalTrials.gov study NCT04272151. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Non-invasive MRD Assessment in Multiple Myeloma
ClinicalTrials.gov study NCT05625971. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Aponermin-Based Bridging Therapy Prior to CAR-T Infusion in Relapsed/Refractory Multiple Myeloma Patients With Extramedullary Disease
ClinicalTrials.gov study NCT06793475. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.