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54,099 results for “Expression”
Supplementary materials for [BRAF-induced EHF expression affects TERT in aggressive papillary thyroid cancer]
<p>Supplementary figures and tables for [BRAF-induced EHF expression affects TERT in aggressive papillary thyroid cancer].</p>
Interborough Express GTFS
<p>A GTFS file describing a proposed schedule for the Interborough Express in New York City using the information provided from the current project proposal.</p>
Gene Expression, Metabolic Data, and Protein Expression in Angiotensin II-Stimulated Cardiomyocytes: A Comprehensive Dataset
Open the record for dataset details and reuse information.
miRNA expression in THP1 cell line
<p><span>This data was collected via a databank on human cellular microRNAome built by McCall MN et al when searching for the expression of different miRNAs in the THP1 cell line</span></p>
Humanoid facial expressions as a tool to study human behaviour
<p>Dataset and MATLAB codes relative to the kinematic study titled <em>Humanoid facial expressions as a tool to study human behaviour (Lombardi G., Sciutti A., Rea F., Vannucci F., Di Cesare G, Scientific Reports 2024, DOI: https://doi.org/10.1038/s41598-023-45825-6) </em></p> <p><strong>analysis.m</strong> is the main matlab code for data organization and peak values extraction</p> <p><strong>VelocityCurves.m</strong>, <strong>AccelerationCurves.m</strong> and <strong>HeightCurves.m</strong> are codes to extract and plot mean velocity, acceleration and trajectory curves respectively and visualize comparison between congruent and incongruent conditions.</p> <p><strong>order.mat</strong> contains the order of experimental conditions</p> <p><strong>subject_kinamatic_data</strong> contains the kinematic dataset. Each subject folder contains different runs saved in .csv and .excel format (these are loaded in code analysis.m) </p> <p><strong>For additional information contact Dr. Alessandra Sciutti, alessandra.sciutti@iit.it</strong></p> <p> </p>
Data and Code for "Detecting context-dependence in the expression of life history tradeoffs"
<p>This repository hosts the data, R scripts, and Stan models needed to reproduce results and figures from the article <em>Detecting context-dependence in the expression of life history tradeoffs.</em></p> <p>See the README file for a description of the different files contained in this repository.</p>
Multimodal contrastive learning for spatial gene expression prediction using histology images
<p>we employed two human breast cancer datasets and one human cutaneous squamous cell carcinoma (cSCC) dataset.</p>
Dataset for Improved differential expression analysis of miRNA-seq data by modeling competition to be counted
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RT PCR data for publication Transplantation of neural stem cells improves recovery of stroke affected mice and induces cell-specific changes in GSDMD and MLKL expression
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Raw data and metadata associated with the manuscript: "Organ and ontogeny-specific steroidal glycoside diversity is associated with differential expression of steroidal glycoside pathway genes in two Solanum dulcamara leaf chemotypes"
<p>Raw LC-MS and RT-qPCR data and metadata associated with the manuscript: "Ontogeny and organ-specific steroidal glycoside diversity is associated with differential expression of steroidal glycoside pathway genes in two <em>Solanum dulcamara</em> leaf chemotypes", accepted at Plant Biology.</p>
Full-length huntingtin Q23 expression and purification for SAXS experiments – 29th January 2018
<p>Huntingtin structure-function open lab notebook project</p>
Determining CD34 expression in the presence and absence of stroma
<p>Determining whether OCI-AML-20 cells require stroma for CD34 expression.</p>
Expression of NSD3short-3xFLAG in Multiple Cell Lines
<p><strong>SGC Open Notebook Project to Characterize the HMTase NSD3</strong></p> <p><strong>Exp018 Objective:</strong>To generate cell lines stably expressing NSD3-Short-3xFLAG in relevant cell backgrounds. These cell lines can be used to assay phenotypes associated with over-expression and to study NSD3-short protein-protein / protein-chromatin interactions. The lentiviral vectors used here have been modified by replacing an IRES bicistronic element with a T2A self-cleaving peptide sequence (cloning described in exp-016) for expression of NSD3short-3xFLAG and a puromycin selection marker.</p>
Mutagenesis to Replace IRES with T2A in NSD3-Short-3xFLAG Lentiviral Expression Vector
<p><strong>SGC Open Notebook Project to Characterize the HMTase NSD3</strong></p> <p><strong>Exp016 Objective: </strong>Bicistronic elements are common features in lentiviral expression systems that allow expression of two protein products from a single promoter. The two most common bicistronic elements are the internal ribosome entry site (IRES), which allows cap-independent translation of a second open reading frame within an mRNA, and the 2A system, which introduces a self-cleaving peptide between two desired protein products. There are several advantages to the the 2A system over an IRES, which include matched expression levels of your two protein products of interest as well as having a smaller footprint (~1/10 size in kb), which may improve viral titre. Therefore, I will use site-directed mutagenesis to alter the NSD3short lentiviral expression plasmid to replace the IRES sequence with a T2A sequence.</p>
Determining the plasticity of CD34 expression
<p>Determining if OCI-AML-20 cells can regain CD34 expression.</p>
PyShEx - Python implementation of Shape Expressions
<p>ShEx interpreter for ShEx 2.0</p>
Measuring E-cadherin Expression in NSD3short Overexpressing H1299 Cells
<p><strong>SGC Open Notebook Project to Characterize the HMTase NSD3</strong></p> <p><strong>Exp021 Objective:</strong> During epithelial to mesenchymal transitioning (EMT), transcription networks become activated and cytoskeletal rearrangements take place. These events promote migratory capacity and invasiveness. Cadherins are a family of cell adhesion molecules central in transitioning to a more mesenchymal state. E-cadherin, a marker for polarized epithelial cells, is downregulated during EMT. Here, I investigate the effect of NSD3short overexpression on E-cadherin expression in H1299 cells, which would support NSD3 as a EMT driver.</p>
Differential gene expression results from DESeq2
<p>Differential gene expression results from DESeq2</p>
NSD3-Short Represses E-cadherin Expression in A549 Lung Epithelial Cancer Cells
<p><strong>SGC Open Notebook Project to Characterize the HMTase NSD3</strong></p> <p><strong>Exp024 Objective: </strong>In a previous experiment (exp023), we show that siRNA-mediated knockdown of NSD3 increases expression of E-cadherin, a marker of epithelial cell identity. To determine which isoform of NSD3 is involved in promoting epithelial to mesenchymal transition, I have designed siRNA that targets either the long or short isoform and again use E-cadherin expression as a marker. Additionally, I have started using A549 lung epithelial cancer cells (https://www.atcc.org/Products/All/CCL-185) as my primary model. This cell line proliferates faster and is more amenable to <em>in vitro</em> experimentation than the H1299 cell line I was using previously.</p>
Quantification of E-cadherin Expression in H1299 NSD3 Knockdown Cells
<p><strong>SGC Open Notebook Project to Characterize the HMTase NSD3</strong></p> <p><strong>Exp023 Objective: </strong>Having observed downregulation of E-cadherin protein levels in response to NSD3 overexpression in H1299 cells (exp021), I was next interested in testing the consequences of NSD3 knockdown. To do so, I transfected H1299 cells with siRNA targeting NSD3, both short and long isoforms, and assayed E-cadherin expression by western blotting. </p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.