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Figure 3 from: Suciati S, Laili ER, Haula H, Tumewu L, Nuengchamnong N, Suphrom N, Widyawaruyanti A (2024) Phytoconstituents, Antioxidant, and cholinesterase inhibitory activities of the leaves and stem extracts of Artocarpus sericicarpus. Pharmacia 71: 1-8. https://doi.org/10.3897/pharmacia.71.e112499

Figure 3 Base peak chromatograms (BPC) of the a. leaves and b. stem ethanolic extracts of A. sericicarpus.

Figure 1 from: Suciati S, Laili ER, Haula H, Tumewu L, Nuengchamnong N, Suphrom N, Widyawaruyanti A (2024) Phytoconstituents, Antioxidant, and cholinesterase inhibitory activities of the leaves and stem extracts of Artocarpus sericicarpus. Pharmacia 71: 1-8. https://doi.org/10.3897/pharmacia.71.e112499

Figure 1 Concentration-dependent response of A. sericicarpus extracts against AChE (a) and BChE (b); each value is expressed as means ± SEM (n = 3). LE : leaves ethanolic extract; LW: leaves water extract; SE: stem ethanolic extract; SW: stem water extract

Figure 4 from: Suciati S, Laili ER, Haula H, Tumewu L, Nuengchamnong N, Suphrom N, Widyawaruyanti A (2024) Phytoconstituents, Antioxidant, and cholinesterase inhibitory activities of the leaves and stem extracts of Artocarpus sericicarpus. Pharmacia 71: 1-8. https://doi.org/10.3897/pharmacia.71.e112499

Figure 4 Molecular networking of the compounds from the leaves and stem extracts of A. sericicarpus (a) with expansion of selected clusters (b).

Figure 2 from: Suciati S, Laili ER, Haula H, Tumewu L, Nuengchamnong N, Suphrom N, Widyawaruyanti A (2024) Phytoconstituents, Antioxidant, and cholinesterase inhibitory activities of the leaves and stem extracts of Artocarpus sericicarpus. Pharmacia 71: 1-8. https://doi.org/10.3897/pharmacia.71.e112499

Figure 2 Radical scavenging effect of A. sericicarpus extracts in DPPH (a) and ABTS (b) assays; each value is expressed as means ± SEM (n = 3). LE : leaves ethanolic extract; LW: leaves water extract; SE: stem ethanolic extract; SW: stem water extract.

Figure 2 from: Hartati FK, Nafisah W, Sutanto A, Saati EA, Khairoh M, Sjamsiah (2024) Aqueous black rice (Oryza sativa L. indica) extract enhanced the activation of CD4+ and CD8+ T cells in mouse breast cancer model. Pharmacia 71: 1-7. https://doi.org/10.3897/pharmacia.71.e113442

Figure 2 Aqueous black rice (ABR) extract reduced the relative number of CD4+IL17+, CD4+TNFα+, and CD4+IFNγ+ cytokine production. A, C, E. were flow cytometry diagram; B, D, F. were the graph of flow cytometry results. The bar in the graph shows the calculation results as the mean ± SD of the relative number of cytokine production. *P<0.05, indicate significant different. The group in this study were normal group; Cancer, DMBA 15 mg/kg BW; Cis, DMBA 15 mg/kg BW + Cisplatin 5 mg/kg BW; ABR1, DMBA 15 mg/kg BW + aqueous black rice extract 0.2 g/kg BW; ABR2, DMBA 15 mg/kg BW + aqueous black rice extract 0.3 g/kg BW; ABR3, DMBA 15 mg/kg BW + aqueous black rice extract 0.4 g/kg BW; ABR4, DMBA 15 mg/kg BW + aqueous black rice extract 0.5 g/kg BW.

Figure 1 from: Hartati FK, Nafisah W, Sutanto A, Saati EA, Khairoh M, Sjamsiah (2024) Aqueous black rice (Oryza sativa L. indica) extract enhanced the activation of CD4+ and CD8+ T cells in mouse breast cancer model. Pharmacia 71: 1-7. https://doi.org/10.3897/pharmacia.71.e113442

Figure 1 Aqueous black rice (ABR) extract increased the relative number of CD4+CD62L- cells and CD8+CD62L- cells. A, C. Show flow cytometry diagrams, and B, D. Show graphs of the flow cytometry results. The bars in the graphs show the calculated results as the mean ± SD of the relative number of CD4+ and CD8+ cell activations. *P<0.05 indicates a significant difference. The groups in this study included the following groups: Normal; Cancer, DMBA 15 mg/kg BW; Cis, DMBA 15 mg/kg BW + Cisplatin 5 mg/kg BW; ABR1, DMBA 15 mg/kg BW + ABR extract 0.2 g/kg BW; ABR2, DMBA 15 mg/kg BW + ABR extract 0.3 g/kg BW; ABR3, DMBA 15 mg/kg BW + ABR extract 0.4 g/kg BW; and ABR4, DMBA 15 mg/kg BW + ABR extract 0.5 g/kg BW.

Figure 3 from: Hartati FK, Nafisah W, Sutanto A, Saati EA, Khairoh M, Sjamsiah (2024) Aqueous black rice (Oryza sativa L. indica) extract enhanced the activation of CD4+ and CD8+ T cells in mouse breast cancer model. Pharmacia 71: 1-7. https://doi.org/10.3897/pharmacia.71.e113442

Figure 3 Aqueous black rice (ABR) extract effect on mammary mice histology based on Hematoxylin & Eosin staining (M: 400x). D, ductal; AT, adipose tissue; arrow, cancer cell. The group in this study were normal group; Cancer, DMBA 15 mg/kg BW; Cis, DMBA 15 mg/kg BW + Cisplatin 5 mg/kg BW; ABR1, DMBA 15 mg/kg BW + aqueous black rice extract 0.2 g/kg BW; ABR2, DMBA 15 mg/kg BW + aqueous black rice extract 0.3 g/kg BW; ABR3, DMBA 15 mg/kg BW + aqueous black rice extract 0.4 g/kg BW; ABR4, DMBA 15 mg/kg BW + aqueous black rice extract 0.5 g/kg BW.

The extraction results of high-rise building areas in 32 typical cities in China.

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Direct Intraocular Lens Extraction Using a Newly Developed Lens-Grabbing Forceps

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Figure 1 from: Satria D, Sitorus P, Dalimunthe A, Waruwu SB, Asfianti V (2024) Oral acute toxicity study of ethanol extract of Mobe leaves (Artocarpus lacucha Buch-Ham) in Wistar rats. Pharmacia 71: 1-8. https://doi.org/10.3897/pharmacia.71.e117500

Figure 1 Organ histopathology (Staining: Hematoxylin and eosin). (C: Normal control group treated with CMC Sodium 0.5%, TI: Treatment group treated with 2000 mg, TII: Treatment group treated with 5000 mg).

DataFrame for SPSS - Music Therapy and Anxiety in Cuban Adult Patients Undergoing Tooth Extractions

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MySQL dump for finding optimal parameters for data augmentation techniques in publication "Leveraging Data Augmentation for Process Information Extraction"

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Supplementary material 1 from: Sadaqa E, Utami RA, Mudhakir D (2024) In vitro cytotoxic and genotoxic effects of Phyllanthus niruri extract loaded chitosan nanoparticles in TM4 cells and their influence on spermatogenesis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e112138

Supplementary information

Figure 7 from: Sadaqa E, Utami RA, Mudhakir D (2024) In vitro cytotoxic and genotoxic effects of Phyllanthus niruri extract loaded chitosan nanoparticles in TM4 cells and their influence on spermatogenesis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e112138

Figure 7 Imaging of cellular morphological change in the presence of ChNP and PNNP. TM4 cells were incubated in the absence of nanoparticles (a) and in the presence of ChNP at 50 µg/mL (b), PNNP at 125 µg/mL (c), and ChNP at 200 µg/mL (d). Images were captured 2 h after transfection using a 20× lens on a CLSM (Olympus FV-1200) and the nucleus was stained with Hoechst 33342 (blue). The bar indicates 50 µm.

Figure 9 from: Sadaqa E, Utami RA, Mudhakir D (2024) In vitro cytotoxic and genotoxic effects of Phyllanthus niruri extract loaded chitosan nanoparticles in TM4 cells and their influence on spermatogenesis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e112138

Figure 9 Claudin 11 expression in the presence of ChNP and PNNP. TM4 cells were incubated with ChNP 50 µg/mL, PNNP 125 µg/mL and ChNP 200 µg/mL for 24 h. a. Confocal images of claudin 11 expression after cells were incubated with a secondary antibody goat anti-rabbit IgG Alexa Fluor 488 (green) and the nucleus was stained with Hoechst 33342 (blue). The bars indicate 50 µm; b. Histogram of downregulation claudin 11 expression. The results are shown as mean ± SE of two separate studies (n = 50). ns (not significant) p > 0.05. Stars (***) indicate significance when compared with the control group (untreated cells) (p < 0.001). Pound signs (###) demonstrate significance compared with ChNP 50 µg/mL.

Figure 8 from: Sadaqa E, Utami RA, Mudhakir D (2024) In vitro cytotoxic and genotoxic effects of Phyllanthus niruri extract loaded chitosan nanoparticles in TM4 cells and their influence on spermatogenesis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e112138

Figure 8 Connexin 43 expression in the presence of ChNP and PNNP. TM4 cells were incubated with ChNP 50 µg/mL, PNNP 125 µg/mL and with ChNP 200 µg/mL for 24 h. a. Confocal images of connexin 43 expression after cells were incubated with a secondary antibody goat anti-rabbit IgG Alexa Fluor 488 (green) and the nucleus was stained with Hoechst 33342 (blue). The bars indicate 50 µm. b. Histogram of downregulation of connexin 43 expression. The results are shown as mean ± SEM of two separate studies (n=50). ns (not significant) p > 0.05. Stars (***) indicate significance when compared with the control group (untreated cells) (p < 0.001). Pound signs (###) demonstrate significance compared with ChNP 50 µg/mL.

Figure 6 from: Sadaqa E, Utami RA, Mudhakir D (2024) In vitro cytotoxic and genotoxic effects of Phyllanthus niruri extract loaded chitosan nanoparticles in TM4 cells and their influence on spermatogenesis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e112138

Figure 6 DNA breakage caused by ChNP and PNNP using FHA. TM4 cells were incubated with various concentration of ChNP (25, 50, 200 µg/mL) and PNNP (62.5, 125, 500 µg/mL) for 2 h. Positive control 100 µm H2O2 was used and incubated for 15 min. Photomicrograph obtained by Inverted Microscope Olympus IX73. Single stranded DNA was stained with ethidium bromide of a. NEgative control (untreated cells); b. H2O2; c.ChNP 25 µg/mL; d.ChNP 50 µg/mL; e.ChNP 200 µg/mL; f.PNNP 62.5 µg/mL; g.PNNP 125 µg/mL; h.PNNP 500 µg/mL. The bar indicates 5 µm. i. Histogram showing DNA damage level using NDF from several randomly selected microscope images. The results are shown as mean ± SEM of three independent experiments (n=150). ns (not significant) p > 0.05. ***p < 0.001 when compared to the corresponding control group.

Figure 4 from: Sadaqa E, Utami RA, Mudhakir D (2024) In vitro cytotoxic and genotoxic effects of Phyllanthus niruri extract loaded chitosan nanoparticles in TM4 cells and their influence on spermatogenesis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e112138

Figure 4 Cell viability percentage after 24 hours of exposure to various concentrations of ChNP and PNNP assessed by CCK8 test. The values are presented as mean ± standard deviation (SD) (n = 3). All data were analyzed using One-way ANOVA. The stars indicate significant difference between control negative (untreated cells) and various treatment groups (P < 0.05 significantly different, p-value ≥ 0.05 was determined as non-significant (ns). A p-value score of between 0.01 and 0.05 was considered significant (*), between 0.01 and 0.001 as very significant (**), and < 0.001 as extremely significant (***).

Figure 3 from: Sadaqa E, Utami RA, Mudhakir D (2024) In vitro cytotoxic and genotoxic effects of Phyllanthus niruri extract loaded chitosan nanoparticles in TM4 cells and their influence on spermatogenesis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e112138

Figure 3 Illustration of the TGA, DTG, and DTA curves for A.ChNP and B.PNNP. DTA curves are represented in green, DTG curves in red, and TGA curves in blue.

Figure 5 from: Sadaqa E, Utami RA, Mudhakir D (2024) In vitro cytotoxic and genotoxic effects of Phyllanthus niruri extract loaded chitosan nanoparticles in TM4 cells and their influence on spermatogenesis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e112138

Figure 5 DNA damage caused by ChNP and PNNP using comet assay. TM4 cells were incubated with various concentrations of ChNP and PNNP for 2 h. Positive control 100 µm H2O2 was used and incubated for 15 min. Comet images demonstrating the degree of DNA damage on TM4 cells were captured using Inverted Microscope Olympus IX73. Single stranded DNA was stained with ethidium bromide. Comet images displayed untreated cells as control (a), H2O2-treated cells (b), and ChNP-treated cells at concentrations of 25 µg/mL (c), 50 µg/mL (d), and 200 µg/mL (e), as well as PNNP-treated cells at concentrations of 62.5 µg/mL (f), 125 µg/mL (g), and 500 µg/mL (h). The bar indicates 5 µm. Quantitative assessment of DNA damage was performed by measuring olive tail moment (i) and % tail DNA (j). The data are presented as the mean ± SEM of three independent trials (n=200), ns (not significant) (***p < 0.001, **p < 0.01, *p < 0.05 when compared to the corresponding control group).