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146 results for “Ganoderma”
Tensile strength of Ganoderma pure mycelium - raw data
<p>The dataset consists of tensile strength values of pure mycelium of <em>Ganoderma lingzhi</em> and <em>Ganoderma sessile</em> produced using liquid state fermentation. The substrate for liquid state fermentation was supplemented with 0,5% of lignin and 2% of lignin (reference was 0% lignin). Raw data from universal testing machine are also provided. Another variant is a modification of obtained mycelium leather with glycerol treatment (immersion of samples in 20% glycerol solution for 24 hours).</p>
Development The Potentiality of β-1,3/1,6-D-Glucan (Polysaccharide Peptide) From Mycelia Extract of Indonesia's Ganoderma Lucidum as Adjuvant Therapy in Patients With Cardiometabolic Syndrome
ClinicalTrials.gov study NCT05079529. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
PsP Ganoderma Lucidum Supplementation and Biomarker Changes in Smokers
ClinicalTrials.gov study NCT07316400. IPD Sharing: NO. Countries: 1. Publications: 3.
Supplementary: Comparative mitogenomics provide new insights into phylogeny of Ganoderma
<p>FA files: Supplementary I.15core-genes.cds; Supplementary II.52samples.atp9 & nad4L;</p> <p>Excel files: Supplementary III.Mitogenomes_annotation tables; Supplementary IV.nucleic_acid.stat; Supplementary V. synteny.list</p>
Supplementary material for: Cytotoxic properties of free and nano-encapsulated methanolic extracts of Ganoderma mushrooms
<p>These are data and supplementary materials for the manuscript "<span>Cytotoxic properties of free and nano-encapsulated methanolic extracts of <em>Ganoderma</em> mushrooms"</span></p>
Fig. 5 in Lanostane-type triterpenoids from the mycelial mat of Ganoderma lucidum and their hepatoprotective activities
Fig. 5. Effects of compounds 1, 6, and 8–10 (15 μM) on ALT activity (A), AST activity (B), LDH activity (C) and GSH level (D) in HepG2 cells. Results are expressed as the mean SEM (n 3). NAC was used as positive control (15 μM). (#) P <0.05 and (##) P <0.01 with respect to the normal group; (*) P <0.05 and (**) P <0.01 ± = with respect to the model group.
Fig. 4 in Lanostane-type triterpenoids from the mycelial mat of Ganoderma lucidum and their hepatoprotective activities
Fig. 4. Hepatoprotective effects of the indicated compounds against H2O2-induced injury in HepG2 cells. Compounds were used at 15 μM. Results are expressed as the mean SEM (n 4). NAC was used as positive control (15 μM). (##) P <0.01 with respect to the normal (untreated) group; (*) P <0.05 and (**) P <0.01 with ± = respect to the model (H2O2-treated) group.
Fig. 6 in Lanostane triterpenoids from cultivated fruiting bodies of basidiomycete Ganoderma mbrekobenum
Fig. 6. Computed ECD spectra of 1 (blue curve) and ent-1 (red curve) and experimental ECD spectrum (black curve). The vertical axis represents the experimental ellipticity. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 3 in Metabolic fingerprinting of Ganoderma spp. using UHPLC-ESI-QTOF-MS and its chemometric analysis
Fig. 3. Structures of five isomeric compounds with the molecular formula C30H42O7 and molecular mass 514.2931 found in the G44 sample.
Fig. 2 in Metabolic fingerprinting of Ganoderma spp. using UHPLC-ESI-QTOF-MS and its chemometric analysis
Fig. 2. General chemical structure of a typical triterpene showing the position of various side chains and list of side chains typically found in Ganoderma.
Fig. 1 in Metabolic fingerprinting of Ganoderma spp. using UHPLC-ESI-QTOF-MS and its chemometric analysis
Fig. 1. (a) Total ion chromatogram of G44 mushroom extract in ESI negative mode (b) Extracted ion chromatogram (EIC) of G44 mushroom extract in ESI negative mode.
Fig. 4 in Meroterpenoids containing benzopyran or benzofuran motif from Ganoderma cochlear
Fig. 4. Comparison of the calculated ECD and experimental CD spectra in MeOH. A: The calculated ECD spectrum of (1R,2S,3R)-1 at CAM-B3LYP/ def2SVP level, σ = 0.20 eV; shift = 0 nm. B: The calculated ECD spectrum of (3S)-2 at CAM-B3LYP/def2SVP level, σ = 0.2 eV; shift = +23 nm.
Fig. 6. NRK-52 E in Meroterpenoids containing benzopyran or benzofuran motif from Ganoderma cochlear
Fig. 6. NRK-52 E cells were incubated with TGF-β1 (10 ng/mL) for 48 h in the absence or presence of substances (20 μM). Antibodies are fibronecitn, collagen I, α-SMA. GW was used as a positive control. GW: GW788388.
Fig. 5 in Meroterpenoids containing benzopyran or benzofuran motif from Ganoderma cochlear
Fig. 5. Meroterpenoids attenuate PA-induced IR in myotubes. (A) C2C12 cell proliferation in response to substances at 20 μM by CCK-8 assay. (B) Substances improved insulin-stimulated glucose uptake in IR model. (C–D) C2C12 were treated with substances at 20 μM for 24 h in IR model, and the expression of p-AKT was determined by using Western blot analysis. Substances ()-1, (+)-2 and (+)-9 improved insulin-stimulated glucose uptake in a dose-dependent manner. Metformin (Met) was used as a positive control. ##P <0.01 compared with no-PA treatment control; *P <0.05 and **P <0.01 compared with insulin treatment alone.
Fig. 6 in Spiroganodermaines A G from Ganoderma species and their activities against insulin resistance and renal fibrosis
Fig. 6. Compounds inhibit renal fibrosis in vitro. (A) NRK-52E cells were treated with 20 μM for 48 h, and cell viability was determined by using the CCK-8 assay. (B, E and F) Compounds at 20 μM affect renal fibrosis-related protein expression. GW788388 was used as a positive control. (C) NRK-52E cells were treated with 5, 10 and 20 μM of ()-7 for 48 h, and cell viability was determined by using the CCK-8 assay. (D, G and H) Compound ()-7 dose-dependently inhibits fibronectin and α-SMA expression. GW788388 was used as a positive control. The results were represented Mean ± SEM. *P <0.05, **P <0.01, ***P <0.001, ****P <0.0001 compared with TGF-β1 alone. #P <0.05 ##P <0.01, ###P <0.001, and ####P <0.0001 compared with DMSO alone.
Fig. 5 in Spiroganodermaines A G from Ganoderma species and their activities against insulin resistance and renal fibrosis
Fig. 5. Attenuation of insulin-induced IR in myotubes. (A) C2C12 cell proliferation in response to compounds at 40 μM by CCK-8 assay. (B) C2C12 were treated with 40 μM for 24 h, and glucose uptake was determined. Metformin (Met) was used as a positive control. (C) Compound (+)-7 improves insulin-stimulated glucose uptake in IR model. (D–F) Expression of p-AKT and p-IRS1 were determined by Western blot. Compound (+)-7 improves attenuated insulin signal pathway disruption in dose-dependent manner. #P <0.05 and ###P <0.001 compared with no-insulin treatment control; *P <0.05 and **P <0.01 compared with insulin treatment alone; $$$P <0.001 and $$$$P <0.0001 compared with insulin treatment control.
Fig. 4 in Structures of ganorbifates C-I, seven previously undescribed lanostanoids from the mushroom Ganoderma orbiforme, and insights of computed biosynthesis with DFT
Fig. 4. NOE correlations and comparison between experimental and calculated ECD spectra for compound 1.
Fig. 5 in Twelve undescribed derivatives of ganoderic acid isolated from Ganoderma luteomarginatum and their cytotoxicity against three human cancer cell lines
Fig. 5. The apoptosis rate of compound 1 in HGC-27 cells. (A) The pro-apoptotic effect of compound 1 in HGC-27 cells was analyzed by flow cytometry. (B) Apoptosis rates of the control group and drug groups. Compound 1 treatment at 3.13, 6.25, 12.5, and 25 μM resulted in a significant increase in apoptosis rates in HGC-27 cells. Data are shown as mean ± SD of three independent experiments. *P <0.05 vs. untreated control.
Fig. 4 in Twelve undescribed derivatives of ganoderic acid isolated from Ganoderma luteomarginatum and their cytotoxicity against three human cancer cell lines
Fig. 4. The pro-apoptotic effect of compound 1 on HGC-27 cells. The cells were treated with different concentrations of 1 for 48 h and visualized for apoptotic bodies under fluorescent microscopy after staining with Hoechst 33,258.
Fig. 4 in Lanostane-type triterpenoids from Ganoderma applanatum and their inhibitory activities on NO production in LPS-induced BV-2 cells
Fig. 4. Experimental (black line) and calculated (red line) ECD spectra of 1–5 (A–E) and their enantiomers in MeOH. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.