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NIH funding notice PA-18-373

Mentored Clinical Scientist Research Career Development Award (Parent K08 - No Independent Clinical Trials)

Closed on January 7, 2019.

Posted
November 21, 2017
Close date
January 7, 2019
Activity codes
K08
Institutes taking part
NCI, NEI, NHLBI, NHGRI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIDA, NIEHS, NIGMS, NIMH, NIMHD, NCCIH, NINDS

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PA-16-191 Mentored Clinical Scientist Research Career Development Award (Parent K08)
  2. 2 steps back: PA-14-046 Mentored Clinical Scientist Research Career Development Award (Parent K08)
  3. 3 steps back: PA-11-193 Mentored Clinical Scientist Research Career Development Award (Parent K08)
  4. 4 steps back: PA-10-059 Mentored Clinical Scientist Research Career Development Award (Parent K08)
  5. 5 steps back: PA-09-042 Mentored Clinical Scientist Research Career Development Award (K08)
  6. 6 steps back: PA-06-512 Mentored Clinical Scientist Research Career Development Award (K08)
  7. 7 steps back: PA-00-003

Replaced by PA-19-117.

Who won it before

1,061 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $179,294,247 in first-year total cost, median $170,193.

Most frequent study sections

  1. Career Development Study Section (J)[NCI-J]145
  2. NHLBI Mentored Clinical and Basic Science Study Section[MCBS (MA)]93
  3. NST-1 Study Section[NST-1]87
  4. Digestive Diseases and Nutrition C Study Section[DDK-C]67
  5. NHLBI Mentored Clinical and Basic Science Study Section[MCBS (JA)]67

Most frequent institutions

  1. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO61
  2. MASSACHUSETTS GENERAL HOSPITAL52
  3. UNIVERSITY OF MICHIGAN AT ANN ARBOR51
  4. STANFORD UNIVERSITY44
  5. WASHINGTON UNIVERSITY44
Competing awards under PA-18-373 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2019Lineage identification and targeted therapeutics in acute leukemia1K08CA230172-01A1GLASS, JACOB LOWELLSLOAN-KETTERING INST CAN RESEARCH, NY$300,766NCI
2019Targeting cell cycle dysregulation in GIST1K08CA241085-01SCHAEFER, INGA-MARIEBRIGHAM AND WOMEN'S HOSPITAL, MA$285,490NCI
2019Mechanisms underlying tumor-infiltrating tissue resident memory T cell generation and maintenance1K08CA230164-01A1GANESAN, ANUSHA PREETHIUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$274,920NCI
2019Competition, Bundled Care Payment, and Low-Value Cancer Care1K08CA234431-01O'NEIL, BROCKUNIVERSITY OF UTAH, UT$261,328NCI
2019Prediction of interval breast cancer risk using genetic variants1K08CA237829-01SHIEH, YIWEYUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$260,330NCI
2019Understanding and addressing sub-optimal responses to CAR T cell therapy for Multiple Myeloma1K08CA241400-01SMITH, ERIC LSLOAN-KETTERING INST CAN RESEARCH, NY$260,099NCI
2019Development and Clinical Implementation of an Artificial Intelligence Tool to Predict Risk of Upgrade of Ductal Carcinoma In Situ1K08CA241365-01BAHL, MANISHAMASSACHUSETTS GENERAL HOSPITAL, MA$259,979NCI
2019Understanding the effects of the Oncology Care Model on cancer care for dual eligible patients1K08CA237638-01HERREL, LINDSEY ALLISONUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$256,480NCI
2019De Novo Nucleotide Synthesis as a Mediator of Radiation Resistance and a Therapeutic Target in Glioblastoma1K08CA234416-01WAHL, DANIEL RUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$256,400NCI
2019Understanding the Adoption and Impact of New Risk Assessment Technologies in Prostate Cancer Care1K08CA237872-01LEAPMAN, MICHAEL STUARTYALE UNIVERSITY, CT$254,417NCI
2019Prognostic value of quantitative HPV viral load in determining cervical cancer treatment response and recurrence1K08CA230170-01A1GROVER, SURBHIUNIVERSITY OF PENNSYLVANIA, PA$254,417NCI
2019Multimodal study of cognitive impairment following radiation therapy for locally advanced head and neck cancer1K08CA237881-01MCDONALD, ANDREW MUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$253,956NCI
2019A Phagocytosis Modulating Nanomedicine for Targeted Breast Cancer Immunotherapy1K08CA241070-01JIANG, WENUT SOUTHWESTERN MEDICAL CENTER, TX$253,377NCI
2019Mechanistic Determinants of Follicular-Helper T-cell Lymphomagenesis1K08CA241089-01NG, SAMUEL YAO-MINGDANA-FARBER CANCER INST, MA$250,577NCI
2019Genomic characterization of tumor heterogeneity in recurrent small cell lung cancer through research autopsy1K08CA241309-01CHEN, HUI-ZIOHIO STATE UNIVERSITY, OH$248,735NCI
2019Chromatin Modifier Gene Mutation and Enhancer Dysfunction in Bladder Cancer1K08CA237842-01LEE, BYRON HCLEVELAND CLINIC LERNER COM-CWRU, OH$243,205NCI
2019The Pro-Tumor Immunologic Niche of the Liver1K08CA236874-01ILYAS, SUMERA I.MAYO CLINIC ROCHESTER, MN$242,898NCI
2019Dissecting the role of ELOVL2 in Drusen Biogenesis and Age Related Macular Degeneration1K08EY030510-01CHAO, DANIEL LUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$241,085ZEY1
2019Exploiting principles of timing-dependent synaptic plasticity to treat amblyopia1K08EY030164-01GAIER, ERIC DEANBOSTON CHILDREN'S HOSPITAL, MA$239,256ZEY1
2019Impact of Oncologic Therapy on Clonal Hematopoiesis and Subsequent Risk of Therapy-Related Leukemia1K08CA241318-01BOLTON, KELLY LEIGHSLOAN-KETTERING INST CAN RESEARCH, NY$238,864NCI
2019Tumor suppressor roles of TFEB in the development and maintenance of myeloid leukemia1K08CA237627-01YUN, SEONGSEOKH. LEE MOFFITT CANCER CTR & RES INST, FL$238,752NCI
2019Integrin-Linked Kinase in Papillary Thyroid Cancer-Associated Fibroblasts and the Tumor Microenvironment1K08CA230196-01A1SHIRLEY, LAWRENCE ANDREWOHIO STATE UNIVERSITY, OH$234,909NCI
2019The Role of APOE Signaling in Microglia in Glaucoma1K08EY030160-01MARGETA, MILICAMASSACHUSETTS EYE AND EAR INFIRMARY, MA$234,328ZEY1
2019Role of tumor burden in limiting durable reinvigoration by PD-1 blockade1K08CA230157-01A1HUANG, ALEXANDERUNIVERSITY OF PENNSYLVANIA, PA$228,870NCI
2019Mechanisms of radiation-induced tumor cell death and survival in cervical cancer1K08CA237822-01MARKOVINA, STEPHANIEWASHINGTON UNIVERSITY, MO$228,774NCI
2019Mitochondrial Respiratory Chain Dysfunction in Primary Open Angle Glaucoma1K08EY029765-01A1CUI, QI NUNIVERSITY OF PENNSYLVANIA, PA$227,417ZEY1
2019The Development of Gene Therapy Using SIRT1 Signaling to Treat Chronic Glaucoma1K08EY030163-01ROSS, AHMARA G.UNIVERSITY OF PENNSYLVANIA, PA$227,125ZEY1
2019Mechanisms regulating chimeric antigen receptor T-cell activity in cancer1K08CA237740-01SINGH, NATHANWASHINGTON UNIVERSITY, MO$226,684NCI
2019Investigating the non-cell autonomous immune effects of mutant p53 in pancreatic cancer1K08CA241341-01SIOLAS, DESPINANEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$225,979NCI
2019Understanding programs of invasion and metastasis in head and neck cancer1K08CA237732-01PURAM, SIDHARTH VENKATAWASHINGTON UNIVERSITY, MO$218,796NCI
2019Cell-Free Nucleic Acids for Early Treatment Response Assessment of Hepatocellular Cancer1K08CA238711-01CHAUDHURI, AADELWASHINGTON UNIVERSITY, MO$216,467NCI
2019Adenosine Signaling and Macular Degeneration1K08EY029484-01A1MOHSENIN, AMIRUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$214,363ZEY1
2019Unraveling the Molecular Function of Mosaic, a gene mediating immune dysregulation1K08AI137301-01A1CHAN, ALICEUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$212,328AITC
2019Immune Evasion in Pancreatic Cancer1K08CA241084-01DIAMOND, MARK STEPHENUNIVERSITY OF PENNSYLVANIA, PA$208,413NCI
2019Deconvolution of pro- and anti-viral responses to Dengue virus and Zika Virus infections1K08AI130381-01A1CARLIN, AARON F.UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$203,796MID
2019Using data science to measure the impact of opioid agonist therapy in patients admitted with Staphylococcus aureus bloodstream infections1K08DA048163-01GOODMAN, DAVIDUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$203,040BGES
2019Spreading depolarizations and brain dysfunction following traumatic brain injury1K08NS110988-01NGWENYA, LAURA BENJAMINUNIVERSITY OF CINCINNATI, OH$201,014NST
2019Determinants of functional brain connectivity after subarachnoid hemorrhage1K08NS112601-01CHUNG, DAVID YOUNGMASSACHUSETTS GENERAL HOSPITAL, MA$200,880NST
2019Improving assessment of prostate cancer bone metastases using advanced diffusion imaging1K08EB026503-01A1SEIBERT, TYLER MICHAELUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$200,720ZEB1
2019Detection of disease-relevant CD8+ T cells in Multiple Sclerosis1K08NS107619-01A1SABATINO, JOSEPH JOHNUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$200,178NST
2019Intratumoral functional connectivity with implications on synaptogenesis and aphasia recovery in adult astrocytic WHO II-III glioma1K08NS110919-01HERVEY-JUMPER, SHAWN L.UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$200,054NST
2019Leveraging CTLs targeting highly networked epitopes to suppress the latent HIV-1 reservoir1K08AI140960-01A1GAIHA, GAURAV DASMASSACHUSETTS GENERAL HOSPITAL, MA$199,800AIDS
2019Innate Immune Response to Aspergillus fumigatus Cell Wall Carbohydrates1K08AI141755-01REEDY, JENNIFER LYNNEMASSACHUSETTS GENERAL HOSPITAL, MA$199,763MID
2019Novel pathways in C9ORF72-associated ALS and dementia1K08NS104270-01A1MORDES, DANIEL ADAMMASSACHUSETTS GENERAL HOSPITAL, MA$199,684NST
2019Molecular Mechanisms of Diabetic Retinal Ganglion Cell Dysfunction and Neurovascular Crosstalk in Early Diabetic Retinopathy1K08EY029766-01SACHDEVA, MIRA MENONJOHNS HOPKINS UNIVERSITY, MD$199,413ZEY1
2019Memory T follicular helper cell kinetics and localization during recall immune responses to tetanus vaccination1K08AI141761-01A1FROSCH, ANNE ELIZABETH PARKERHENNEPIN HEALTHCARE RESEARCH INSTITUTE, MN$199,260AITC
2019Identification of circulating and tissue-specific autoimmune responses in checkpoint inhibitor-induced immune-related adverse events1K08AI139375-01A1OH, DAVID YOONSUKUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$199,098AITC
2019Deciphering the role of autophagy receptor phosphorylation and host kinases in the targeting of M. tuberculosis to autophagy1K08AI146267-01BUDZIK, JONATHAN MUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$199,098MID
2019The HIV Latent Reservoir, Suboptimal Immune Response on Antiretroviral Therapy, and Exogenous Cytokine Therapies1K08AI143391-01ANTAR, ANNUKKA AIDA ROSEJOHNS HOPKINS UNIVERSITY, MD$198,720AIDS
2019Protein palmitoylation in synuclein pathophysiology1K08NS110876-01HO, GARY P. H.BRIGHAM AND WOMEN'S HOSPITAL, MA$198,720NST
2019Novel Imaging and host-directed therapy in pediatric CNS TB1K08AI139371-01A1TUCKER, ELIZABETH WINANSJOHNS HOPKINS UNIVERSITY, MD$198,720MID
2019Defining maternal and neonatal antibody responses in congenital Zika virus infection1K08AI139341-01A1MOHR, EMMA LUNIVERSITY OF WISCONSIN-MADISON, WI$197,964MID
2019Neural dynamics underlying rule-based decision-making1K08MH120434-01LOVEJOY, LEE PHIPPSNEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NY$197,640CP
2019A longitudinal study of prenatal maternal obesity and the fetal origins of impulsivity in Puerto Rican children1K08MH117452-01A1LUGO-CANDELAS, CLAUDIA INEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NY$197,373ZRG1
2019Development of a novel platform for the discovery of antigen-specific TCRs1K08CA235525-01SEET, CHRISTOPHERUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$196,884NCI
2019Using Default Opioid Prescription Settings to Limit Excessive Opioid Prescribing to Adolescents and Young Adults1K08DA048110-01CHUA, KAO-PINGUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$196,560DIRH
2019Safety and tolerability of new and repurposed drugs for MDR-TB treatment1K08AI141740-01VELASQUEZ, GUSTAVO EDUARDOBRIGHAM AND WOMEN'S HOSPITAL, MA$196,478MID
2019Autoimmunity to Axoglial Apparatus Proteins in Multiple Sclerosis1K08NS112576-01PATTERSON, KRISTINA RAEUNIVERSITY OF PENNSYLVANIA, PA$196,020NST
2019Effects of Memory T Cells on the Response to Cecal Ligation and Puncture1K08GM132794-01TAYLOR, MATTHEW DAVIDFEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, NY$195,480SAT
2019Dissecting Mechanisms of Granuloma Macrophage Polarization and Granuloma Formation in Chronic Salmonella Infection1K08AI143796-01PHAM, TRUNG HOANG MINHSTANFORD UNIVERSITY, CA$194,292MID
2019Sepsis and the benefits of permissive hypoxia1K08GM134220-01SHAEFI, SHAHZADBETH ISRAEL DEACONESS MEDICAL CENTER, MA$193,860SAT
2019Biology of Influenza Virus Transmission1K08AI141759-01A1ORTIGOZA, MILA BRUMNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$193,652MID
2019Mechanisms of Volatile Anesthetic Modulation of Tandem Pore Potassium Channels1K08GM132781-01RIEGELHAUPT, PAUL MICHAELWEILL MEDICAL COLL OF CORNELL UNIV, NY$193,320BPNS
2019Perioperative Targeted Genotyping in Glioma1K08NS107634-01A1SHANKAR, GANESHMASSACHUSETTS GENERAL HOSPITAL, MA$193,298NST
2019Development of Accurate and Interpretable Machine Learning Algorithms for their application in Medicine1K08EB026500-01A1VALDES, GILMERUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$191,912ZEB1
2019Molecular Characterization and Personalized Approaches to Non-Hodgkin Lymphoma from Circulating Tumor DNA1K08CA241076-01KURTZ, DAVID MATTHEWSTANFORD UNIVERSITY, CA$191,304NCI
2019Macrophages and Resistance to Mycobacterium Tuberculosis Infection in Humans1K08AI143926-01SIMMONS, JASONUNIVERSITY OF WASHINGTON, WA$190,296MID
2019Parkinson's disease susceptibility in carriers of lysosomal storage disorder genes1K08NS112467-01ROBAK, LAURIE ABAYLOR COLLEGE OF MEDICINE, TX$190,210NST
2019Placental malaria: The role of inflammation at the maternal-fetal interface1K08AI141728-01GAW, STEPHANIE LINAUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$189,986MID
2019Human Cellular Immune Programming Against Invasive Salmonella1K08AI143923-01RAPAKA, REKHA RUNIVERSITY OF MARYLAND BALTIMORE, MD$189,864MID
2019Enhanced NGR/p75/KAL9 Signaling and Impaired Dendritic Morphogenesis across Development1K08MH118513-01GRUBISHA, MELANIE JEANUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$189,540ZRG1
2019Hepatic Response in Advance Age after Burn Injury1K08GM134185-01IDROVO, JUAN PABLOUNIVERSITY OF COLORADO DENVER, CO$189,043SAT
2019The Role of the IL-1 Receptor in the AKI to CKD transition1K08GM132689-01PRIVRATSKY, JAMIE RDUKE UNIVERSITY, NC$187,908SAT
2019Social Epidemiology of Ebola Virus Disease1K08AI139361-01A1RICHARDSON, EUGENE THOMASHARVARD MEDICAL SCHOOL, MA$187,477MID
2019Natural killer cell repertoire in HIV infection outcomes1K08AI138640-01A1VENDRAME, ELENASTANFORD UNIVERSITY, CA$187,380AIDS
2019The Role of DEPDC5 in Epileptogenesis and Brain Malformations1K08NS107637-01A1YUSKAITIS, CHRISTOPHER JOSEPHBOSTON CHILDREN'S HOSPITAL, MA$187,272NST
2019Astrocyte-specific IL-1RI signaling effects following traumatic brain injury1K08NS110829-01NEWELL, ELIZABETHUNIVERSITY OF IOWA, IA$187,128NST
2019Obesity dysregulates immune and metabolic status in asthma and alters infection susceptibility.1K08AI135091-01A1HENRICKSON, SARAH ECHILDREN'S HOSP OF PHILADELPHIA, PA$186,948ZAI1
2019Ambulatory Assessment of Simultaneous Alcohol and Marijuana Use: Impact on Alcohol Use and Consequences1K08AA027551-01GUNN, RACHEL LYNBROWN UNIVERSITY, RI$186,922AA
2019Machine learning-based segmentation and risk modeling for real-time prediction of major arterial bleeding after pelvic fractures1K08EB027141-01A1DREIZIN, DAVIDUNIVERSITY OF MARYLAND BALTIMORE, MD$186,183ZEB1
2019Gender-specific effects of puberty on airway epithelial differentiation in asthma1K08AI141765-01A1CHIARELLA, SERGIO EMAYO CLINIC ROCHESTER, MN$185,760AITC
2019UNRAVELLING THE MECHANISMS OF EPILEPSY-DEPRESSION COMORBIDITY IN A GENETIC MOUSE MODEL OF TEMPORAL LOBE EPILEPSY1K08NS110924-01KRISHNAN, VAISHNAVBAYLOR COLLEGE OF MEDICINE, TX$185,486NST
2019Brain Health in Breast Cancer Survivors: Interaction of Menopause and Endocrine Therapy1K08CA241337-01VAN DYK, KATHLEENUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$184,965NCI
2019Mechanisms of AIRE SAND-Domain Variants in Autoimmunity1K08AI141734-01A1ABBOTT, JORDANNATIONAL JEWISH HEALTH, CO$184,788AITC
2019The roles of anti-apoptotic proteins BCL-XL and MCL1 in mediating survival of high-grade serous ovarian cancer following drug-induced DNA damage1K08CA237871-01STOVER, ELIZABETH HARMONDANA-FARBER CANCER INST, MA$184,711NCI
2019Role of Interferon-gamma in Clearance of Chlamydia trachomatis Infection in Women1K08AI146278-01JORDAN, STEPHEN J.INDIANA UNIVERSITY INDIANAPOLIS, IN$183,863MID
2019Tricytotoxic T cells protect against intracellular infection in human skin1K08AR074552-01BALIN, SAMUEL JACKSONUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$183,600AMS
2019Comparing Ovine Models of Congenital Heart Disease to Distinguish Pathobiological Mechanisms Underlying Pulmonary Vascular Disease: Toward Precision Medicine for CHD1K08HL146933-01KAMENY, REBECCA JOHNSONUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$180,142MCBS
2019The role of antigen binding strength in CAR T cell activity1K08CA237868-01RICHMAN, SARAH ANNCHILDREN'S HOSP OF PHILADELPHIA, PA$178,314NCI
2019Macrophage and monocyte TBK1 function in host defense against influenza1K08HL143271-01A1HAGAN, ROBERT STEWARTUNIV OF NORTH CAROLINA CHAPEL HILL, NC$178,217MCBS
2019The identification of endocardial regulatory elements in cardiac regeneration1K08HL148518-01WU, ROLAND SUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$177,987MCBS
2019Elucidating the role of type 2 immunity in skin homeostasis1K08AR075880-01RICARDO-GONZALEZ, ROBERTO RAFAELUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$177,660AMS
2019Hypoxia, HIF-1, and the progression of nonalcoholic fatty liver disease in obstructive sleep apnea1K08HL143140-01A1MESARWI, OMARUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$177,552MCBS
2019Interleukin-31 at the neuroimmune interface of pruritus and dermatitis1K08AR074556-01FASSETT, MARLYS SUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$177,498AMS
2019SLAMF7 Regulates Synovial Macrophages in Rheumatoid Arthritis1K08AR075850-01SIMMONS, DAIMON P.BRIGHAM AND WOMEN'S HOSPITAL, MA$177,120AMS
2019Tension-induced SGK-1 Signaling in AAA1K08HL143169-01A1RUDDY, JEAN MARIEMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$176,472MCBS
2019Role of the Novel MicroRNA-125b in Pulmonary Hypertension Associated with Pulmonary Fibrosis1K08HL141995-01A1UMAR, SOBANUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$175,824MCBS
2019Probing Notch regulation of alloimmunity to uncover novel strategies for graft-versus-host disease control1K08HL145116-01A1RADOJCIC, VEDRANUNIVERSITY OF UTAH, UT$174,960MCBS
2019Metabolic control of monocyte development and function by amino acids1K08AR074562-01LEE, PUI YUENBOSTON CHILDREN'S HOSPITAL, MA$173,587AMS
2019Genetic variation in the metal transporter ZIP8 and impact on the innate immune response in the gut1K08DK114478-01A1MELIA, JOANNA MILLER PELOQUINJOHNS HOPKINS UNIVERSITY, MD$173,220DDK
2019Computationally guided modulation of cortical-striatal activity: Toward brain stimulation-based treatments for impulsive and risky decision making1K08MH117347-01A1DOUCETTE, WILDER TDARTMOUTH-HITCHCOCK CLINIC, NH$173,016PMDA
2019Biomarkers of Immune Activation in African Americans with CKD1K08DK117068-01A1CHEN, TERESAJOHNS HOPKINS UNIVERSITY, MD$172,852DDK
2019The Role of Family with Sequence Similarity 3D (FAM3D) in Cardioprotection and Inflammation after Myocardial Infarction1K08HL140200-01A1RHEE, JAMESMASSACHUSETTS GENERAL HOSPITAL, MA$172,800MCBS
2019Signatures of dysfunctional mitochondrial fatty acid oxidation that predispose to early-onset preeclampsia1K08HL146963-01GRAY, KATHRYN JOHNSONMASSACHUSETTS GENERAL HOSPITAL, MA$172,800MCBS
2019Purinergic Modulation of NKT Cells Ameliorates Hyperoxic Lung Injury1K08HL141694-01A1HANIDZIAR, DUSANMASSACHUSETTS GENERAL HOSPITAL, MA$172,800MCBS
2019Specialized Pro-Resolving Mediator Regulation of NK Cells in Human RSV Bronchiolitis1K08HL145098-01A1DUVALL, MELODY G.BRIGHAM AND WOMEN'S HOSPITAL, MA$172,680ZHL1
2019Role of autophagy in epidermal differentiation and homeostasis1K08AR075846-01SIMPSON, CORY LUNIVERSITY OF PENNSYLVANIA, PA$172,260AMS
2019Neurophysiological Assessments of Network Dysfunction in Alzheimer's Disease1K08AG058749-01A1RANASINGHE, KAMALINI GAYATHREEUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$172,098NIA
2019Dissecting the Cellular and Molecular Mechanisms Contributing to Craniofacial Fibrous Dysplasia1K08DE028946-01WENTWORTH, KELLY LEEUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$172,098DSR
2019Role of Endo180 Regulation in Tissue Fibrosis1K08HL145015-01A1PODOLSKY, MICHAELUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$172,098MCBS
2019Identifying the Molecular Target of Two Novel Compounds Active Against Non-replicating Mycobacterium tuberculosis and Delineating the Role of the Putative Target, InhA, in Non-replicating States1K08AI139360-01A1SAITO, KOHTAWEILL MEDICAL COLL OF CORNELL UNIV, NY$172,006MID
2019The Therapeutic Role for LOLX2 in Pulmonary Hypertension1K08HL145132-01STEPPAN, JOCHENJOHNS HOPKINS UNIVERSITY, MD$171,720MCBS
2019Engineering a power switch to study the contribution of stem cell-derived cardiomyocytes on heart regeneration1K08HL145135-01A1TAMPAKAKIS, EMMANOUILJOHNS HOPKINS UNIVERSITY, MD$171,720MCBS
2019Microbiota mechanisms and biomarkers in GVHD1K08HL143189-01A1PELED, JONATHANSLOAN-KETTERING INST CAN RESEARCH, NY$171,612MCBS
2019Tumor-Mediated Hearing Loss in Neurofibromatosis Type II1K08DC017508-01DINH, CHRISTINE THUYVANUNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$171,198CDRC
2019Dissecting a novel prefrontal cortical pathway regulating feeding behavior1K08DK118201-01A1ROSS, RACHEL AMCLEAN HOSPITAL, MA$170,820DDK
2019Defining Immunology Frailty as a Predictor of Human Liver Allograft Recipient Futility1K08DK118187-01A1LUNSFORD, KERI ELIZABETHMETHODIST HOSPITAL RESEARCH INSTITUTE, TX$170,792DDK
2019Role of DPP4 in Kidney Inflammation and Injury1K08DK115886-01A1NISTALA, RAVIUNIVERSITY OF MISSOURI-COLUMBIA, MO$170,747DDK
2019Multi-Omics Analysis of the Association of Polyunsaturated Fatty Acids with Asthma and Allergy in Childhood1K08HL148178-01LEE-SARWAR, KATHLEEN ABRIGHAM AND WOMEN'S HOSPITAL, MA$170,640MCBS
2019Characterization of Early Response to Chronic Lung Injury using Chest CT1K08HL145118-01ASH, SAMUELBRIGHAM AND WOMEN'S HOSPITAL, MA$170,320MCBS
2019Mechanisms of Endothelial Cell Dysfunction in Critically Ill Children1K08HL136898-01A1PIERCE, RICHARD WYALE UNIVERSITY, CT$169,884MCBS
2019Protection of kidney from autoimmunity by modulating co-stimlatory signaling1K08DK120868-01MURAKAMI, NAOKABRIGHAM AND WOMEN'S HOSPITAL, MA$169,860DDK
2019Understanding Real-World Outcomes of Endovascular Treatment of Claudication1K08HL144924-01A1OSBORNE, NICHOLAS HAROLDUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$169,560MCBS
2019Fibro-adipogenic remodeling of the diaphragm in obesity-associated respiratory dysfunction1K08HL147377-01BURAS, ERIC DUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$169,464MCBS
2019Evaluation of multiple medication exposures concurrently using a novel algorithm1K08DK119475-01VAJRAVELU, RAVY KUPPALAPALLEUNIVERSITY OF PENNSYLVANIA, PA$169,440DDK
2019Molecular genetic bases of polycystic and tubulointerstitial kidney diseases1K08DK119642-01BESSE, WHITNEY ELISEYALE UNIVERSITY, CT$169,440DDK
2019Alveolar macrophage-derived extracellular vesicles inhibit influenza infection in epithelial cells1K08HL149051-01A1SCHNEIDER, DANIEL JUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$169,019MCBS
2019Mechanisms of extrahepatic biliary proliferation and regeneration1K08DK122114-01RAZUMILAVA, NATALIYAUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$168,900DDK
2019Evaluating T cell Exhaustion in Systemic Lupus Erythematosus1K08AR075056-01TILSTRA, JEREMY SCOTTUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$167,940AMS
2019Identification of a mesenchymal progenitor cell hierarchy in adipose tissue1K08DK122099-01MERRICK, DAVID MICHAELUNIVERSITY OF PENNSYLVANIA, PA$167,940DDK
2019Using Participatory Systems Modeling to Understand Community Influences on Cardiovascular Health1K08HL143133-01A1ROY, BRITAYALE UNIVERSITY, CT$167,881MCBS
2019Modifiers of Tissue Factor Procoagulant Activity1K08HL146797-01SCHULMAN, SOLBETH ISRAEL DEACONESS MEDICAL CENTER, MA$167,832MCBS
2019Defining the Role of lnc-TECRL in Maladaptive Cardiac Remodeling1K08HL146964-01TOPKARA, VELI KEMALCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$167,724MCBS
2019Mechanisms of Pulmonary Microbiota-Induced Inflammation and Vascular Dysfunction in Neonatal Lung Injury1K08HL141652-01A1LAL, CHARITHARTH VIVEKUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$167,616MCBS
2019CYP1 Inhibition as a New Therapeutic Strategy for Doxorubicin Cardiomyopathy1K08HL145019-01ASNANI, AARTIBETH ISRAEL DEACONESS MEDICAL CENTER, MA$167,400MCBS
2019Astrocyte Reaction in Alzheimer's Disease1K08AG064039-01SERRANO-POZO, ALBERTOMASSACHUSETTS GENERAL HOSPITAL, MA$167,400ZAG1
2019The Urinary Microbiota and Host Inflammation in Lower Urinary Tract Symptoms1K08DK118176-01A1ACKERMAN, A. LENORECEDARS-SINAI MEDICAL CENTER, CA$167,237DDK
2019The Role of PPM1G in Apolipoprotein E Biology and Atherosclerotic Cardiovascular Disease1K08HL145095-01BENSON, MARK DANIELBETH ISRAEL DEACONESS MEDICAL CENTER, MA$167,048MCBS
2019Single Cell Analysis of Kidney Transplant Antibody Mediated Rejection1K08DK120953-01MALONE, ANDREW FRANCISWASHINGTON UNIVERSITY, MO$165,758DDK
2019Personal Surgical Planning to Avoid Hip Dislocation after Total Hip Arthroplasty: Concept of Functional Safe Zone1K08AR073933-01A1ESLAM POUR, AIDINUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$165,499AMS
2019The Next Step: Regadenoson mitigates ischemia reperfusion injury and is renal protective in a 48 hour porcine model of resuscitative ECMO1K08HL146995-01ROESER, MARKUNIVERSITY OF VIRGINIA, VA$165,456MCBS
2019Tissue Resident Immune Cells in Human Pancreas.1K08DK122130-01WEISBERG, STUART PCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$165,456DDK
2019The role of ARF6 in the progression of diabetic kidney disease1K08DK119466-01A1LIN, JAMIEUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$165,240DDK
2019Utility of virtual crossmatch in deceased donor kidney transplantation1K08DK119576-01A1PUTTARAJAPPA, CHETHANUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$164,260DDK
2019Ubiquitin signaling in epigenetic regulation of neuronal development1K08HD099314-01FERGUSON, COLE JOHNWASHINGTON UNIVERSITY, MO$164,015CHHD
2019Personalized Model Systems to Predict and Investigate CFTR Drug Response in CF1K08HL144825-01A1BREWINGTON, JOHN JOSEPHCINCINNATI CHILDRENS HOSP MED CTR, OH$163,620MCBS
2019Circadian Clock Dysregulation in a Model of Obstructive Sleep Apnea1K08HL148551-01SMITH, DAVID FCINCINNATI CHILDRENS HOSP MED CTR, OH$163,579MCBS
2019Urothelial IL-6 Signaling in the Host Defense Against Urinary Tract Infections1K08DK122119-01CHING, CHRISTINA BRESEARCH INST NATIONWIDE CHILDREN'S HOSP, OH$163,495DDK
2019Mitochondrial metabolic regulation of lung epithelium: alveolar generation and regeneration1K08HL143138-01A1HAN, SEUNGHYENORTHWESTERN UNIVERSITY AT CHICAGO, IL$163,296MCBS
2019The Structural Basis of Antiarrhythmic Drug Binding in Voltage-gated Ion Channels1K08HL145630-01LENAEUS, MICHAEL JUNIVERSITY OF WASHINGTON, WA$163,148MCBS
2019Targeted non-genotoxic hematopoietic stem cell transplant conditioning approach1K08HL141635-01A1CHANDRAKASAN, SHANMUGANATHANEMORY UNIVERSITY, GA$163,080MCBS
2019A genetic and molecular approach to understanding allelic and phenotypic heterogeneity in Acrofacial dysostosis, Cincinnati-type1K08HL143177-01A1WEAVER, KATHRYN NICOLECINCINNATI CHILDRENS HOSP MED CTR, OH$162,980MCBS
2019Tailored Adaptation of the AHRQ VTE QI Guide to Local Hospital Context.1K08HL145139-01YANG, ANTHONY D.NORTHWESTERN UNIVERSITY AT CHICAGO, IL$162,756MCBS
2019Cholesterol regulation by the cargo receptor SURF41K08HL148552-01EMMER, BRIAN TUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$162,650MCBS
2019A Molecular Imaging Approach to Immuno-Metabolic Characterization of Vessel Wall Macrophages1K08HL144911-01A1TAVAKOLI, SINAUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$162,540MCBS
2019Degradation of Toll-Like Receptor 8 by RNF216 in response to plasma MicroRNA’s – A Novel Mechanism Regulating Inflammation in Acute Lung Injury1K08HL144820-01EVANKOVICH, JOHN WUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$162,539MCBS
2019Bridging the gap between mutation & cellular effects: Defining the mechanisms of hypertrophic cardiomyopathy1K08HL145020-01A1KAWANA, MASATAKASTANFORD UNIVERSITY, CA$162,015MCBS
2019Phosphorylation Control of Fibroproliferative ARDS1K08HL135279-01A1ASCHNER, YAELUNIVERSITY OF COLORADO DENVER, CO$161,803MCBS
2019C3 Mitigates Epithelial Injury in Pneumonia1K08HL148510-01KULKARNI, HRISHIKESH SATISHWASHINGTON UNIVERSITY, MO$161,377MCBS
2019Personalizing Preoperative Stress Testing Using Machine Learning1K08HL141598-01A1PAPPAS, MATTHEWCLEVELAND CLINIC LERNER COM-CWRU, OH$161,047MCBS
2019Impact of Maternal Obesity on Offspring Non-alcoholic Fatty Liver Disease: Role of Bile Acid Homeostasis and Microbiome1K08DK122018-01THOMPSON, MICHAEL DWASHINGTON UNIVERSITY, MO$160,820DDK
2019The role of energy sensor signaling in mitochondrial cardiomyopathy1K08HL145138-01DAI, DAO-FUUNIVERSITY OF IOWA, IA$160,628MCBS
2019Aging and Clostridium difficile infection: interplay of microbiota and host response1K08AG064151-01SHIN, JAE HYUNUNIVERSITY OF VIRGINIA, VA$160,066NIA
2019Sex Differences in Renal Ammonia Metabolism1K08DK120873-01HARRIS, AUTUMN NUNIVERSITY OF FLORIDA, FL$159,966DDK
2019Therapeutic Applications of Factor VIIIa Inactivation in Hemophilia A1K08HL146991-01GEORGE, LINDSEY ALLISONCHILDREN'S HOSP OF PHILADELPHIA, PA$159,948MCBS
2019Aging-associated changes in gut microbiome drive sepsis severity1K08AG061144-01COLBERT, JAMES FUNIVERSITY OF COLORADO DENVER, CO$159,840NIA
2019Establishing roles for the type I interferon/double-stranded RNA response and Helicobacter pylori-specific transcripts in the progression to metaplasia in gastric epithelium1K08DK122116-01SAENZ, JOSE BERNARDOWASHINGTON UNIVERSITY, MO$159,558DDK
2019Pathophysiological Regulation of Metabolism and Energy Use during Heart Failure1K08HL145136-01A1AUBERT, GREGORYLOYOLA UNIVERSITY CHICAGO, IL$159,408MCBS
2019Targeted Treatment of Metastatic Gastroenteropancreatic Neuroendocrine Tumors1K08CA234209-01A1ROSE, JOHN BUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$158,814NCI
2019Impact of Dysfunctional HDL on Platelet Function and in vivo Thrombosis1K08HL145075-01SONG, WENLIANGVANDERBILT UNIVERSITY MEDICAL CENTER, TN$158,760MCBS
2019Mannose binding lectin-dependent complement activation in emphysema1K08HL141770-01A1SERBAN, KARINANATIONAL JEWISH HEALTH, CO$158,652MCBS
2019Integration of early genetic alterations and inflammation in gastroesophageal premalignancy1K08DK120930-01SETHI, NILAYDANA-FARBER CANCER INST, MA$158,040DDK
2019Defining the role of CRH-expressing neurons in Barrington's Nucleus (BN) and Characterizing the other neuronal subpopulations in BN1K08DK120934-01VAN BATAVIA, JASON PHILIPCHILDREN'S HOSP OF PHILADELPHIA, PA$157,223DDK
2019Improving Strategies to Determine Pathogenicity of Variants of Uncertain Significance1K08HG010154-01A1BALDRIDGE, DUSTIN MWASHINGTON UNIVERSITY, MO$156,159GNOM
2019Precision Medicine for Heart Failure: The Role of Genomics in the Efficacy and Racial Disparity of Cornerstone Pharmacotherapy1K08HL146990-01LUZUM, JASMINE AUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$155,639MCBS
2019Dysbiosis of the Sinus Microbiota in Chronic Rhinosinusitis1K08AI146220-01CHO, DO-YEONUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$154,044MID
2019Responses of the Macula to Toxicant Injury: The Role(s) of PGC1α Isoforms in Photoreceptor Neuroprotection.1K08EY028628-01A1MOWAT, FREYANORTH CAROLINA STATE UNIVERSITY RALEIGH, NC$153,825ZEY1
2019The role of GLP-1 in cardiac recovery after bariatric surgery in obesity-induced heart failure1K08HL140000-01A1KINDEL, TAMMY LYNMEDICAL COLLEGE OF WISCONSIN, WI$150,874MCBS
2019Phenotype, dynamics and activation of myocardial B lymphocytes in response to ischemia/reperfusion injury1K08HL145108-01A1ADAMO, LUIGIWASHINGTON UNIVERSITY, MO$150,593MCBS
2019NOVEL ROLE OF SPHINGOLIPIDS IN MAINTAINING VASCULAR HOMEOSTASIS1K08HL141562-01A1FREED, JULIE KMEDICAL COLLEGE OF WISCONSIN, WI$149,794MCBS
2019Interferon-mediated control of neuropathogenic Flaviviruses1K08AI132751-01A1HANNERS, NATASHA WYNDHAMUT SOUTHWESTERN MEDICAL CENTER, TX$148,770MID
2019Wnt Signaling in Bronchopulmonary Dysplasia1K08HL143051-01A1SUCRE, JENNIFER MALCOLMSRYGLEYVANDERBILT UNIVERSITY MEDICAL CENTER, TN$148,705MCBS
2019The presence and significance of hyperopic defocus across the retina in young myopic eyes1K08EY028611-01A1XU, RENFENGTRUSTEES OF INDIANA UNIVERSITY, IN$146,961ZEY1
2019The Role of RBM20 Sequence and Expression in Dilated Cardiomyopathies1K08HL143185-01A1PARIKH, VICTORIASTANFORD UNIVERSITY, CA$144,994MCBS
2019Population Management for Hereditary Cancer Prevention: Implementation, Effectiveness, and Acceptability within a Learning Health System.1K08HG010488-01KNERR, SARAHUNIVERSITY OF WASHINGTON, WA$143,032GNOM
2019Mechanism of disease in TBCK-related intellectual disability syndrome, a novel neurodegenerative disorder with mTOR dysfunction1K08NS109281-01BHOJ, ELIZABETH JOYCECHILDREN'S HOSP OF PHILADELPHIA, PA$142,015NST
2019Comparative Animal Models of Viral Hepatitis1K08AI141767-01A1TOMLINSON, JOY ECORNELL UNIVERSITY, NY$139,701MID
2019The Role of DNAJB6 in Muscle and the Impact of LGMD1D Mutations1K08AR075894-01FINDLAY, ANDREWWASHINGTON UNIVERSITY, MO$139,134AMS
2019Novel Biofilm Inhibitors of Oral Streptococci1K08DE028009-01A1PESAVENTO, RUSSELL PUNIVERSITY OF ILLINOIS AT CHICAGO, IL$138,254DSR
2019Altered postnatal microglial function following fetal inflammation and its effect on long-term neurodevelopment of neonatal mice1K08HD099246-01GISSLEN, TATE A.UNIVERSITY OF MINNESOTA, MN$135,702CHHD
2019Targeting glutamine metabolism during the development and resolution of acute lung injury1K08HL148529-01VIGELAND, CHRISTINE LEEUNIV OF NORTH CAROLINA CHAPEL HILL, NC$134,754MCBS
2019Patient-Specific Induced Pluripotent Stem Cells for Modeling Single Ventricle Congenital Heart Disease1K08HL148553-01PAIGE, SHARON LYNNSTANFORD UNIVERSITY, CA$131,652MCBS
2019The role of LILRB4 in AML progression and immune suppression1K08CA234544-01A1KIM, JAEHYUPUT SOUTHWESTERN MEDICAL CENTER, TX$131,374NCI
2019Utilization of molecular targeted radionuclides to prime immune responses at local and distant metastatic tumor sites1K08CA241319-01PATEL, RAVI BHASKERUNIVERSITY OF WISCONSIN-MADISON, WI$125,895NCI
2019Enteroendocrine cell plasticity during intestinal injury1K08DK122101-01MUEGGE, BRIAN DAVIDWASHINGTON UNIVERSITY, MO$121,799DDK
2019Clinical and viral genomic approaches to evaluate the emergence of Powassan virus1K08AI139348-01A1PIANTADOSI, ANNE LMASSACHUSETTS GENERAL HOSPITAL, MA$111,522MID
2019Profiling Translational Control of Gene Expression and Nascent Proteomic Responses in Erythropoietic Progression and Ribosomopathies1K08DK119561-01FORESTER, CRAIG M.UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$51,120DDK
2019Combined brain and gene network approaches to the developmental hypothesis of schizophrenia1K08MH120564-01ALEXANDER-BLOCH, AARON FELIXYALE UNIVERSITY, CT$27,032NPAS
2018Noninvasive Risk Stratification of Prostate Cancer Using Cell-Free Nucleic Acids1K08CA230156-01 · under PA-16-191GU, WEIUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$284,633NCI
2018The role of catecholamines in immunotoxicity and tumor response of adoptive T cell therapy in cancer1K08CA230179-01 · under PA-16-191STAEDTKE, VERENAJOHNS HOPKINS UNIVERSITY, MD$270,192NCI

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