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NIH funding notice PA-20-203

Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)

Closed on May 7, 2024.

Posted
May 12, 2020
Close date
May 7, 2024
Activity codes
K08
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PA-19-117 Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)
  2. 2 steps back: PA-18-373 Mentored Clinical Scientist Research Career Development Award (Parent K08 - No Independent Clinical Trials)
  3. 3 steps back: PA-16-191 Mentored Clinical Scientist Research Career Development Award (Parent K08)
  4. 4 steps back: PA-14-046 Mentored Clinical Scientist Research Career Development Award (Parent K08)
  5. 5 steps back: PA-11-193 Mentored Clinical Scientist Research Career Development Award (Parent K08)
  6. 6 steps back: PA-10-059 Mentored Clinical Scientist Research Career Development Award (Parent K08)
  7. 7 steps back: PA-09-042 Mentored Clinical Scientist Research Career Development Award (K08)
  8. 8 steps back: PA-06-512 Mentored Clinical Scientist Research Career Development Award (K08)
  9. 9 steps back: PA-00-003

Replaced by PA-24-182.

Who won it before

2,072 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $366,887,492 in first-year total cost, median $172,019.

Most frequent study sections

  1. Career Development Study Section (J)[NCI-J]335
  2. NST-1 Study Section[NST-1]167
  3. NHLBI Mentored Clinical and Basic Science Study Section[MCBS (MA)]154
  4. NHLBI Mentored Clinical and Basic Science Study Section[MCBS (OA)]134
  5. NHLBI Mentored Clinical and Basic Science Study Section[MCBS (JA)]130

Most frequent institutions

  1. MASSACHUSETTS GENERAL HOSPITAL110
  2. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO110
  3. WASHINGTON UNIVERSITY100
  4. STANFORD UNIVERSITY89
  5. UNIVERSITY OF MICHIGAN AT ANN ARBOR89
Competing awards under PA-20-203 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025Liver disease impact on myeloid cells driving immunotherapy resistance in hepatocellular carcinoma1K08CA290152-01A1KEENAN, BRIDGETUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$282,053NCI
2025Lens Capsule Based Extended Drug Delivery Device1K08EY036955-01DEBOER, CHARLES MENO THEODORESTANFORD UNIVERSITY, CA$257,785ZEY1
2025Role of Mertk in pathological neurodevelopment in mice with congenital Zika virus infection1K08NS136766-01A1AGNER, SHANNON CHRISTINEWASHINGTON UNIVERSITY, MO$234,359NST
2025Circuit Modulation in Spinocerebellar Ataxias: Mechanisms and Impact1K08NS134624-01A1SRINIVASAN, SHARAN RAMUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$233,280NST
2025Immune Regulation of the Blood-Brain Barrier1K08NS136723-01A1WILCOX, DOUGLAS ROBERTBRIGHAM AND WOMEN'S HOSPITAL, MA$230,580ZNS1
2025Hippocampal-cortical mechanisms of altered memory consolidation in epilepsy1K08NS140631-01CHIANG, SHARONUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$225,400NST
2025Host-pathogen interactions during Staphylococcus aureus spine infections1K08AI177741-01A1LE, KATHERINE YENKHANGNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$208,332MID
2025Identifying mechanisms of immune dysregulation via severe pediatric SARS-CoV-21K08AI187711-01BODANSKY, AARONUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$200,016MID
2025Autologous Non-viral CRISPR/Cas Homology-directed Repair for Artemis-deficient Severe Combined Immunodeficiency1K08AI187714-01KAN, MATTHEW JUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$200,016MID
2025Understanding the mechanism of tropism specific immune restriction in HIV infection1K08AI184158-01A1PAL, PRIYAWASHINGTON UNIVERSITY, MO$197,366AIDS
2025Dynamic FOXP3 Expression in the Development of Regulatory T cells from Induced Pluripotent Stem Cells1K08AI182485-01A1YIU, GLORIAUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$196,992AITC
2025Macrophage Expression Quantitative Trait Loci and Tuberculosis Pathogenesis1K08AI182475-01A1HONG, HYEJEONGUNIVERSITY OF PENNSYLVANIA, PA$194,940MID
2025The Establishment of Lung Resident Self-Antigen-Specific CD4+ Tregs Following Acute Tissue injury1K08AI187736-01SHIN, DANIEL SEONG-JOOBOSTON CHILDREN'S HOSPITAL, MA$194,740AITC
2025Global Breast and Cervical Cancer Control: Implementing a Bundled Screening Approach in a Resource Limited Setting1K08CA289935-01A1GUTNIK, LILYUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$192,780NCI
2025INVESTIGATING THE MOLECULAR MECHANISMS OF DIFFERENTIATION FAILURE IN NF2 MUTANT NEUROEPITHELIAL STEM CELLS1K08NS140551-01TAILOR, JIGNESHINDIANA UNIVERSITY INDIANAPOLIS, IN$190,485NST
2025Role of Transposable Elements in Septic Immune Aging1K08GM157557-01PEREZ, ALEXENDAR REINALDOUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$190,278SAT
2025The Role of ADAM9 in the Innate Immune Response to SARS-CoV-2 Infection1K08AI180429-01A1BAZZONE, LINDSEY EUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$190,058AITC
2025Microbial Genomic Determinants of Antibiotic Treatment Failure in Staphylococcus aureus Bacteremia1K08AI187747-01PARSONS, JOSHUA BDUKE UNIVERSITY, NC$189,558MID
2025Apolipoprotein E governs lymph node stromal cell function and lipid metabolism during autoimmunity1K08AI187740-01POHOLEK, CATHERINEUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$189,540AITC
2025The role of cortico-striatal circuitry in model-based decision-making1K08MH136338-01A1GERAMITA, MATTHEW A.UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$189,540ZRG1
2025The role of extrachromosomal DNA in HER2-amplified breast cancer1K08CA296931-01WEISER, NATASHA ELISESTANFORD UNIVERSITY, CA$187,887NCI
2025Evaluating mRNA-lipid nanoparticle platforms and adjuvants to overcome maternal antibody interference1K08AI182476-01A1ENGLAND, ROSSCHILDREN'S HOSP OF PHILADELPHIA, PA$184,896AITC
2025Therapeutic Targeting of Apical Periodontal T-Cells in Chronic Oral Inflammation1K08DE034493-01HASIAKOS, SPYRIDON PETERUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$180,943DSR
2025Appraising the Fracture Risk Assessment Tool (FRAX) in persons with rheumatoid arthritis1K08AR083508-01A1ELAM, RACHEL ELIZABETHAUGUSTA UNIVERSITY, GA$177,120AMS
2025Defining the role of Pi16-expressing fibroblasts in mouse and human fibrosing skin disease1K08AR085193-01KINET, MAXIME JEREMIEUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$176,148AMS
2025A high-throughput, multimodal strategy to improve variant classification1K08HG014001-01LANCASTER, MEGANVANDERBILT UNIVERSITY MEDICAL CENTER, TN$172,584GNOM
2025Dysregulation of the unfolded protein response in the pathogenesis of non-alcoholic steatohepatitis1K08DK139370-01A1SHERMAN, MARC SMASSACHUSETTS GENERAL HOSPITAL, MA$172,060DDK
2025DISSECTING THE SPATIAL HETEROGENEITY OF SYNOVIAL INFLAMMATION IN RHEUMATOID ARTHRITIS1K08AR085165-01RESHEF, YAKIR ABRAHAMBRIGHAM AND WOMEN'S HOSPITAL, MA$170,101AMS
2025Elucidating the Role of NAD+ and PARylation in Nephron Endowment1K08DK138291-01A1CLARK, AMANDA JUT SOUTHWESTERN MEDICAL CENTER, TX$168,886DDK
2025Elucidating the neuronal mechanisms underlying cognitive resilience to Alzheimer's Disease1K08AG086586-01A1RAJU, RAVIKIRAN MBOSTON CHILDREN'S HOSPITAL, MA$167,940AGCD
2025Precision Prediction of Right Ventricular Size, Function, and Outcomes in Patients with Repaired Tetralogy of Fallot1K08HL173639-01A1DUONG, SON QUANGICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$167,588MCBS
2025Immuno-Metabolic Regulation of Vascular Dysfunction by CD701K08HL177156-01PANDEY, ARVIND KANTBRIGHAM AND WOMEN'S HOSPITAL, MA$167,400MCBS
2025Developing models of placenta-driven developmental lung injury in human preeclampsia1K08HL177161-01TAGLAUER, ELIZABETHBOSTON MEDICAL CENTER, MA$166,752MCBS
2025The Effect of Hyperoxia on Neonatal Respiratory Progenitor Cell Function1K08HL166967-01A1RAI, NOORALAMCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$166,395MCBS
2025Gene Regulatory Mechanisms of the Coronary Artery Disease Gene PRDM16 on Smooth Muscle Cell Phenotypic Modulation1K08HL177251-01PALMISANO, BRIAN T.STANFORD UNIVERSITY, CA$165,672MCBS
2025More heart transplants through informed donor selection1K08HL177427-01WAYDA, BRIANNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$165,672MCBS
2025Klf2/4 and mechanical signaling in cardiac fibroblasts1K08HL171841-01A1DOMINGUEZ, MARTIN HOELLERDREXEL UNIVERSITY, PA$165,366MCBS
2025The role of Axl signaling in intestinal fibrosis1K08DK138279-01A1STEINER, CALEN ANDREWUNIVERSITY OF COLORADO DENVER, CO$163,825DDK
2025Defining the cellular and molecular consequences in TET2 CHIP1K08HL171833-01A1HEIMLICH, JONATHAN BRETTVANDERBILT UNIVERSITY MEDICAL CENTER, TN$158,544MCBS
2025Metastatic Bone Disease and IL-6 as Drivers of Cachexia in Kidney Cancer1K08AR082457-01A1COLLIER, CHRISTOPHER DAVIDINDIANA UNIVERSITY INDIANAPOLIS, IN$156,210AMS
2025Deep Learning of Renal Scans and Kidney Ultrasounds in Children with Antenatal Hydronephrosis1K08DK137042-01A1WEAVER, JOHNCLEVELAND CLINIC LERNER COM-CWRU, OH$155,011DDK
2025Calcium-mediated paracrine signaling in beta cell cilia1K08DK142012-01DIGRUCCIO, SAMANTHA ADAMSONWASHINGTON UNIVERSITY, MO$153,266DDK
2025Nocturnal hypoxemia dysregulates skeletal muscle protein homeostasis in COPD1K08HL168348-01A1ATTAWAY, AMYCLEVELAND CLINIC LERNER COM-CWRU, OH$151,578MCBS
2025Using novel RNA therapy to understand the role of fibrinogen in thromboinflammation in acute and chronic venous thrombosis1K08HL177422-01DYER, MITCHELL RMEDICAL COLLEGE OF WISCONSIN, WI$151,523MCBS
2025Modeling and prediction of allergic trajectories in children1K08AI182477-01A1GABRYSZEWSKI, STANISLAW JCHILDREN'S HOSP OF PHILADELPHIA, PA$151,444AITC
2025Identifying optimal electrophysiological markers for predicting developmental outcomes in infants1K08HD114880-01A1GREEN, HEATHER LEECHILDREN'S HOSP OF PHILADELPHIA, PA$147,037CHHD
2025Discovery of heart-derived myokines mediating the response to exercise stress via PGC-1a1K08HL177169-01KHETARPAL, SUMEETMASSACHUSETTS GENERAL HOSPITAL, MA$142,776MCBS
2025Harnessing ecDNA Detection in Antigen-Presenting Cells for Anti-Tumor Immunity1K08CA296776-01SCHRANK, BENJAMIN RUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$139,247NCI
2025Interactions between the Gut Microbiome, Intestinal Development and Metabolic Health after Fetal Growth Restriction1K08DK139411-01A1GILLEY, STEPHANIE PRITCHARDUNIVERSITY OF COLORADO DENVER, CO$129,619DDK
2025Impact of Interhospital Disparities in Cardiac Arrest Hospital Care1K08MD018413-01A1HUEBINGER, RYANUNIVERSITY OF NEW MEXICO HEALTH SCIS CTR, NM$117,720ZMD1
2025Characterizing the Impact of Uterine Fibroids on the In-Utero Environment Offspring Consequences1K08HD114850-01A1CAMERON, KATHERINE ELIZABETHJOHNS HOPKINS UNIVERSITY, MD$100,170CHHD
2025Small LIVER Cancer: Development of a Multi-Level Intervention to Improve Access to CURE (LIVER:CURE)1K08CA286847-01A1CHARALEL, RESMIWEILL MEDICAL COLL OF CORNELL UNIV, NY$51,079NCI
2025Insulin receptor condensates in health and disease1K08DK138287-01A1PLATT, JESSE MICHAELMASSACHUSETTS GENERAL HOSPITAL, MA$11,970DDK
2025Building an atlas of B cell mediated protective immunity to alphaviruses1K08AI187716-01RAJU, SARAVANANWASHINGTON UNIVERSITY, MO$1MID
2024Dissecting intrinsic variability in engineered T Cell immunotherapies1K08CA286740-01A1ROTH, THEODORE LEESTANFORD UNIVERSITY, CA$330,942NCI
2024Understanding mechanisms of impaired immunity in the AML bone marrow1K08CA293271-01DEWOLF, SUSAN ESLOAN-KETTERING INST CAN RESEARCH, NY$303,621NCI
2024Molecular Dynamics of Glioma Formation and DNA Damage Response by Mutant IDH11K08CA283279-01A1SHI, DIANADANA-FARBER CANCER INST, MA$299,403NCI
2024Targeted delivery of a VEGF‐blocking scFv by CD70 CAR‐T cells to enhance anti‐tumor activity in renal cell carcinoma1K08CA289948-01LEICK, MARKMASSACHUSETTS GENERAL HOSPITAL, MA$297,728NCI
2024Investigating personalized approaches to de-intensify therapy for nodular lymphocyte-predominant Hodgkin lymphoma1K08CA266824-01A1BINKLEY, MICHAEL SSTANFORD UNIVERSITY, CA$284,784NCI
2024Harnessing human gut-derived Bacteroides to drive systemic anti-tumor immunity1K08CA283272-01A1UPADHYAY, RABINEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$281,606NCI
2024Biomarker-Driven Strategies to Overcome Immunotherapy Resistance in STK11-Deficient NSCLC1K08CA279925-01A1KAUFMAN, JACOB MARCUSOHIO STATE UNIVERSITY, OH$281,370NCI
2024Mechanisms of proinflammatory glial activation in retinal degeneration1K08EY033013-01A1DISTASIO, MARCELLO MICHAELYALE UNIVERSITY, CT$280,704ZEY1
2024Tumor Microenvironment Determinants of TKI Response in Oncogene-Driven Lung Cancer1K08CA282966-01A1SCHENK, ERIN LUNIVERSITY OF COLORADO DENVER, CO$279,465NCI
2024Preference-Based Treatment Valuation in Low-Risk Thyroid Cancer1K08CA293167-01HU, YININUNIVERSITY OF MARYLAND BALTIMORE, MD$279,039NCI
2024Local nano-immune modulation for the systemic treatment of lymphoma1K08CA283285-01A1LIN, ADAM YUHNORTHWESTERN UNIVERSITY AT CHICAGO, IL$275,837NCI
2024Dissecting the cooperation of FOXR2 and ETS transcription factors in FOXR2-expressing diffuse midline gliomas1K08CA279908-01A1TSAI, JESSICA WHEICHILDREN'S HOSPITAL OF LOS ANGELES, CA$262,863NCI
2024Automatic integrated biomarkers to improve prediction of lung cancer outcomes1K08CA286842-01A1JEE, JUSTINSLOAN-KETTERING INST CAN RESEARCH, NY$256,487NCI
2024Development of a novel survey to screen for chemotherapy-induced peripheral neuropathy in young children1K08CA286835-01A1RODWIN, ROZALYNYALE UNIVERSITY, CT$255,769NCI
2024Role of Bruch Membrane Heparan Sulfate in Drusenogenesis in Age-Related Macular Degeneration1K08EY035322-01A1TOOMEY, CHRISTOPHER BUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$254,808ZEY1
2024BCOR/PRC1.1 Inactivation In Splicing Factor Mutant MDS Progression1K08CA282965-01A1VEDULA, RAHULDANA-FARBER CANCER INST, MA$250,507NCI
2024Evaluating, Preparing, and Responding to Care Disruptions and Health Outcomes Among Patients with Breast Cancer Following Severe Storms1K08CA283268-01A1BATES, BENJAMINRUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ$249,218NCI
2024Calming the Cytokine Storm: Unraveling the Biology of CRS and ICANS1K08CA286762-01DIORIO, CAROLINECHILDREN'S HOSP OF PHILADELPHIA, PA$248,509NCI
2024Identification of splice variant derived neo-antigens in head and neck squamous cell carcinoma as targets for tumor vaccine therapy1K08CA276999-01A1GUO, THERESAUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$235,417NCI
2024Understanding the Role of EIF4A2 in Neurodevelopment1K08NS138691-01DUNCAN, ANNA RUTHMASSACHUSETTS GENERAL HOSPITAL, MA$234,630ZNS1
2024Defining Tumor Microenvironmental Interactions that drive THY1-Mediated Treatment Resistance in Glioblastoma1K08NS128271-01A1AL-HOLOU, WAJDUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$233,280NST
2024Optimization and mechanisms of electrical neurostimulation in mouse models of epilepsy1K08NS126730-01A1FOUTZ, THOMASWASHINGTON UNIVERSITY, MO$232,981NST
2024Lung fibrosis impairs tumor immunity and limits immune checkpoint efficacy1K08CA282968-01A1HERZOG, BRETT HOWARDWASHINGTON UNIVERSITY, MO$231,870NCI
2024Mitochondrial mechanisms underlying neural stem and progenitor cell proliferation deficits in 22q11.2 deletion syndrome1K08NS135125-01CAMPBELL, PHILIPUNIVERSITY OF PENNSYLVANIA, PA$231,255NST
2024Determining the Origin and Pathogenicity of Plasma-Derived Alpha-SynucleinStrains1K08NS133286-01A1KANNARKAT, GEORGE TUNIVERSITY OF PENNSYLVANIA, PA$231,255NST
2024Causes and Consequences of Leptomeningeal Bleeding in Cerebral Amyloid Angiopathy1K08NS131530-01A1KOZBERG, MARIEL GAILEYMASSACHUSETTS GENERAL HOSPITAL, MA$230,071ZNS1
2024The Role of Pain-Facilitating Circuits in Chronic Pain after Traumatic Brain Injury1K08NS135185-01A1CHEN, QILIANGSTANFORD UNIVERSITY, CA$228,420NST
2024Mitochondrial Metabolic Regulation of GABAergic Interneurons1K08NS135186-01A1MITHAL, DIVAKAR SINGHLURIE CHILDREN'S HOSPITAL OF CHICAGO, IL$225,180NST
2024Aging-associated changes in the brain's response after a cardiac arrest1K08NS135129-01A1BASAK, JACOBUNIVERSITY OF COLORADO DENVER, CO$224,424NST
2024Understanding the role of BORCS5 in neuronal lysosomal function and neurodegeneration1K08NS131581-01A1MENCACCI, NICCOLO ENORTHWESTERN UNIVERSITY AT CHICAGO, IL$216,963NST
2024Epigenetic regulators define a dynamic chromatin landscape in NUP98-rearranged leukemia1K08CA279891-01A1HEIKAMP, EMILYDANA-FARBER CANCER INST, MA$215,179NCI
2024Discovering the cell type basis of the IT projection system and its dysregulation after perinatal HIE1K08NS133292-01A1RUSS, JEFFREY BDUKE UNIVERSITY, NC$212,895NST
2024Tumor-Immune Interactions and Cisplatin Resistance in Bladder Cancer1K08CA282969-01A1DE CARVALHO, FILIPEBRIGHAM AND WOMEN'S HOSPITAL, MA$210,973NCI
2024Getting Excited about Cortical Malformations: Discovering the Mechanisms Leading to Seizure-prone Neurons in Malformations of Cortical Development1K08NS131572-01A1ALEXANDER, ALLYSON LAURAUNIVERSITY OF COLORADO DENVER, CO$204,884NST
2024Genetic and Transcriptomic Resilience in Chronic Obstructive Pulmonary Disease1K08HL168205-01A1GHOSH, AUYONUPSTATE MEDICAL UNIVERSITY, NY$203,764MCBS
2024Revealing the mechanisms of increased intestinal epithelial cell barrier permeability in peanut allergy1K08AI175655-01A1STEINBACH, ERIN C.UNIV OF NORTH CAROLINA CHAPEL HILL, NC$202,314AITC
2024Mechanisms of a therapeutic DNA vaccine targeting Mycobacterium tuberculosis persisters1K08AI174959-01A1KARANIKA, STYLIANIJOHNS HOPKINS UNIVERSITY, MD$200,880AIDS
2024Engineering Immunity for Broad Protection Against Betacoronaviruses1K08AI180364-01A1MILLER, EMILY HAPPYALBERT EINSTEIN COLLEGE OF MEDICINE, NY$199,584MID
2024Cellular reprogramming of cochlear glial cells to regenerate auditory neurons1K08DC021750-01SHIBATA, SEIJI BUNIVERSITY OF SOUTHERN CALIFORNIA, CA$199,044CDRC
2024Discrete Functions of Basal Forebrain Cholinergic Signaling to Amygdala and Orbitofrontal Cortex in Reversal Learning1K08MH135164-01A1VILLARIN, JOSEPH MANUELNEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NY$197,235NMB
2024The Impact of Anesthetics on Lymphatic Vessel Contractility and Extracellular Fluid Uptake1K08GM155886-01RUSCIC, KATARINA JMASSACHUSETTS GENERAL HOSPITAL, MA$197,080SAT
2024Influence of the Cervicovaginal Phageome on Health and Disease in Women Living with HIV.1K08AI181643-01MONACO, CYNTHIA L.UNIVERSITY OF ROCHESTER, NY$196,452AIDS
2024Using Big Data to Optimize Treatment of Opioid Use Disorder in Pregnancy1K08DA061258-01XU, KEVIN YOUNGWASHINGTON UNIVERSITY, MO$196,236ZRG1
2024Harnessing machine learning to develop new antibiotics for Neisseria gonorrhoeae1K08AI182474-01ANAHTAR, MELIS N.MASSACHUSETTS GENERAL HOSPITAL, MA$196,190MID
2024Understanding developmental neurogenomic mechanisms in externalizing disorders1K08MH135343-01MALLARD, TRAVIS TMASSACHUSETTS GENERAL HOSPITAL, MA$196,083GHD
2024The Role of Propionate Metabolism in Non-Small Cell Lung Cancer1K08CA279653-01A1PARANG, BOBAKWEILL MEDICAL COLL OF CORNELL UNIV, NY$196,020NCI
2024Mechanisms Contributing to T Cell Immune Dysregulation in STAT3 Gain-of-Function1K08AI182483-01SCHMITT, ERICA GWASHINGTON UNIVERSITY, MO$195,894AITC
2024ADAM10 as a molecular specifier of sepsis1K08AI182478-01ALFANO, DANIELLE NICOLEWASHINGTON UNIVERSITY, MO$195,607AITC
2024Unraveling the role of the molecular co-chaperone DNAJC7 in protein homeostasis and neurodegeneration1K08NS133300-01A1RAMANI, BISWARATHANUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$195,570NST
2024Systems Antibody Immunology of the Malaria Sporozoite Vaccine1K08AI180370-01HERMAN, JONATHAN DAVIDBRIGHAM AND WOMEN'S HOSPITAL, MA$195,480MID
2024Enhancing the TCR-induced Response of HLA-E-restricted Regulatory CD8 T Cells to Promote Allograft Tolerance1K08AI182491-01CHOI, JOHN YONGJOONBRIGHAM AND WOMEN'S HOSPITAL, MA$195,126AITC
2024Targetable pathways driving sub-optimal early-life CD8 T cell responses1K08AI177743-01A1BRODSKY, NINAYALE UNIVERSITY, CT$195,068AITC
2024Cannabinoid Receptor Type 2 Agonist as Potential Therapy for Neuroinflammation in HIV-1 Associated Neurocognitive Disorders1K08DA060084-01MIN, ALICE KYUNGSUNICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$194,940HCCS
2024Somatic mutations in autism spectrum disorder1K08MH136407-01MO, ALISABOSTON CHILDREN'S HOSPITAL, MA$194,940GHD
2024Effects of general anesthetics on mitochondrial cellular distribution1K08GM149981-01A1BEDELL, VICTORIA MARIEUNIVERSITY OF PENNSYLVANIA, PA$194,940SAT
2024Assessing Anxiety in Adolescents with Autism Spectrum Disorder: The Role of Autonomic Activity as a Biomarker1K08MH133879-01A1YARGER, HEATHERUNIV OF MARYLAND, COLLEGE PARK, MD$194,797CPDD
2024Plasticity of auditory cortex microglia and perineuronal nets after hearing loss1K08DC022004-01KEMPFLE, JUDITHMASSACHUSETTS EYE AND EAR INFIRMARY, MA$194,400CDRC
2024In vivo enrichment of cell-free DNA to boost sensitivity of circulating nucleic-acid based diagnostics1K08EB036081-01TABRIZI, SHERVINMASSACHUSETTS GENERAL HOSPITAL, MA$193,901ZEB1
2024Elucidating the impact of immune imprinting on SARS-CoV-2 variant vaccination strategies using a humanized mouse model1K08AI180347-01BOWEN, ANTHONYCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$193,644AITC
2024Maternal B cells enforce fetal tolerance1K08AI180350-01ERICKSON, JOHN J.CINCINNATI CHILDRENS HOSP MED CTR, OH$193,212AITC
2024Synaptic protein composition and localization in individuals with schizophrenia1K08MH132042-01A1KALINOWSKI, AGNIESZKASTANFORD UNIVERSITY, CA$192,996ZRG1
2024SARS-CoV-2 immune responses in patients with lymphoma1K08AI178093-01A1CHANG, ANDRESEMORY UNIVERSITY, GA$192,888AITC
2024Cost-Effectiveness of HIV Testing in U.S. Emergency Departments1K08AI181642-01A1BENNETT, CHRISTOPHER LSTANFORD UNIVERSITY, CA$192,672AIDS
2024Piloting an Implementation Strategy for Mainstream Genetic Testing in Colorectal Cancer1K08CA293312-01HOLLIS, ROBERT HUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$192,433NCI
2024Localizing Health Disparities and Predicting Morbidity and Mortality for HIV-Related Opportunistic Infections1K08AI181606-01A1BIELICK, CATHERINEBETH ISRAEL DEACONESS MEDICAL CENTER, MA$191,484AIDS
2024Rapid Anatomic and Quantitative MR Imaging of the Skull Base and Face1K08EB034299-01A1GUENETTE, JEFFREY PBRIGHAM AND WOMEN'S HOSPITAL, MA$191,365ZEB1
2024The impact of obesity on neutrophil swarming in septic surgical patients1K08GM157658-01JALILVAND, ANAHITAOHIO STATE UNIVERSITY, OH$190,620SAT
2024Altered CD4+ T cell responses and resultant asthma following neonatal human metapneumovirus infection1K08AI182486-01EDDENS, TAYLOR JOHNUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$189,756AITC
2024Terminal type-specific cannabinoid CB1 receptor alterations in schizophrenia and cannabis use1K08MH136415-01A1CHOU, SHINN-YIUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$189,540MCNP
2024Intelligent wearable system for preventing medication errors in anesthesiology1K08GM153069-01MICHAELSEN, KELLYUNIVERSITY OF WASHINGTON, WA$188,028SAT
2024Local and systemic immune responses during syphilis infection1K08AI180375-01REID, TARA BRINCKUNIVERSITY OF WASHINGTON, WA$188,024MID
2024ENHANCEMENT OF CD4CAR T-CELL PERSISTENCE IN VIVO1K08AI183990-01BUI, JOHN KUNIVERSITY OF WASHINGTON, WA$186,408AIDS
2024Interactions and mechanisms of bacteriophages and antibiotics in phage cocktails1K08AI173452-01A1NICHOLLS, PAULBAYLOR COLLEGE OF MEDICINE, TX$185,580MID
2024Understanding the role of arginine metabolism in antibiotic treatment failure during Staphylococcus aureus infections1K08AI185310-01FREIBERG, JEFFREY ALEXANDERVANDERBILT UNIVERSITY MEDICAL CENTER, TN$185,544MID
2024Mechanisms of regulatory T cell adaptation to inflammation1K08AI182489-01SKARTSIS, NIKOLAOSMAYO CLINIC ROCHESTER, MN$182,520AITC
2024Induction of Broad Sarbecovirus Immunity Via A Vaccine Engineered From SARS-CoV-2 Heptad Repeat 11K08AI180431-01A1STAMPFER, SAMUEL DAVIDEMORY UNIVERSITY, GA$181,764AITC
2024Resting and Dynamic Brain Glutamate by MRS In Vivo: Relation to Suicidal Behavior1K08MH138753-01HERZOG, SARAHCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$179,680NPAS
2024Defining the Extrinsic and Intrinsic Mechanisms of Vision Loss in Optic Glioma1K08NS133966-01A1TANG, YUNSHUO CAROLINEWASHINGTON UNIVERSITY, MO$178,918NST
2024Elucidating the role of IRF4 in reprogramming the tumor microenvironment in follicular lymphoma1K08CA279652-01A1MONDELLO, PATRIZIAMAYO CLINIC ROCHESTER, MN$178,069NCI
2024Perivascular adipose tissue in the pathogenesis of lupus vasculopathy1K08AR082453-01A1SHI, HONGAUGUSTA UNIVERSITY, GA$177,120AMS
2024Activation of Synovial Lining Fibroblasts in Rheumatoid Arthritis1K08AR082929-01A1SMITH, MELANIE HENNEBRYHOSPITAL FOR SPECIAL SURGERY, NY$175,960AMS
2024Modulating the Microbiome to Enhance Right Ventricular Function in Pulmonary Arterial Hypertension1K08HL168166-01A1PRISCO, SASHA ZHENGUNIVERSITY OF MINNESOTA, MN$175,068MCBS
2024Regulation of signaling pathways mediating epithelial cell injury in the neonatal intestine1K08DK140604-01FRAZER, LAUREN CAROLEUNIV OF NORTH CAROLINA CHAPEL HILL, NC$174,114DDK
2024Eicosanoid Pathways Underlying Disease Risk in Pulmonary Arterial Hypertension1K08HL166950-01A1ALOTAIBI, MONA AUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$174,096MCBS
2024Understanding mitochondrial mutations that drive human tissue aging1K08AG086582-01VANDIVER, AMY R.UNIVERSITY OF CALIFORNIA LOS ANGELES, CA$173,788AGCD
2024Understanding diet-microbiota interactions in small intestine eosinophil tissue residency during homeostasis and eosinophilic granulomatosis with polyangiitis (EGPA)1K08AR084069-01KORN, LISA LENOREYALE UNIVERSITY, CT$173,556AMS
2024Wnt signaling as a driver of pathogenic stromal inflammation in rheumatoid arthritis1K08AR083513-01MUELLER, ALISA ANNEBRIGHAM AND WOMEN'S HOSPITAL, MA$173,247AMS
2024The Physiology and Biochemistry of Sepsis-induced Vasoplegia1K08HL171885-01A1WISE, ERIC STEPHENUNIVERSITY OF MINNESOTA, MN$172,937MCBS
2024Determining the Role of Brain-Derived CCN3 in Bone and Marrow Fat Metabolism1K08DK133674-01A1BABEY, MURIELUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$172,248DDK
2024Intestinal mitochondrial dysfunction and the gut-brain-immune axis in models of Parkinson's Disease1K08DK134872-01A1VIDELOCK, ELIZABETH JANEUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$172,032DDK
2024Contributions of gastrointestinal Staphylococcus aureus and other gut microbiota to pediatric atopic dermatitis1K08AR084045-01KARAGOUNIS, THEODORA KATERINANEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$172,005AMS
2024Diversity generation in the gastrointestinal microbiome1K08DK138316-01MACADANGDANG, BENJAMINUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$171,992DDK
2024Multi-scale Analysis of the Role of Skeletal Muscle Actin Mutations in Dilated Cardiomyopathy1K08HL173569-01GARG, ANKITJOHNS HOPKINS UNIVERSITY, MD$171,811MCBS
2024Individualization of Fetal Growth Assessment using Maternal Genetics and Explainable AI1K08HD113835-01BLUE, NATHAN RICHARDUNIVERSITY OF UTAH, UT$171,720CHHD
2024Donor DNMT3a-mediated regulation of Graft-vs-Host-Disease and the Graft-vs-Tumor effect in allogeneic hematopoietic cell transplantation1K08HL168154-01A1KTENA, YIOULIJOHNS HOPKINS UNIVERSITY, MD$171,720MCBS
2024IL17 mediates chorioamnionitis induced lung damage1K08HL171892-01A1JAIN, VIRAL GUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$171,095MCBS
2024Genetic and phenotypic adaptations of vancomycin-resistant Enterococcus faecium during recurrent bloodstream infection1K08AI185312-01STELLFOX, MADISON ELAINEUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$171,089MID
2024Myelofibrosis impacts the hematopoietic niche through TNF-a1K08HL166969-01A1OETJEN, KAROLYN ANNWASHINGTON UNIVERSITY, MO$170,948MCBS
2024The Impact of Soluble ST2 on Lung Injury Onset and Resolution1K08HL173572-01ALLADINA, JEHANMASSACHUSETTS GENERAL HOSPITAL, MA$170,640MCBS
2024Role of a Novel Methyltransferase in Liver Lipid Metabolism1K08DK136706-01A1NGUYEN, ALEXANDERUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$170,532DDK
2024Role of GM-CSF and impaired lipid metabolism in the pathogenesis of PAP1K08HL166970-01A1LEE, ELINORUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$170,532MCBS
2024Lac operon-dependent metabolism in Enterobacteriaceae and its role in liver disease-associated infections1K08DK138319-01A1HECHT, AARON LUNIVERSITY OF PENNSYLVANIA, PA$170,520DDK
2024Optimizing decision-making to improve maternal outcomes in high-risk pregnant patients with hypertensive disorders - Resubmission - 11K08HD111687-01A1PENFIELD, CHRISTINANEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$170,420CHHD
2024Advancing the clinical actionability of polygenic scores for coronary artery disease1K08HL168238-01A1PATEL, ANIRUDDHMASSACHUSETTS GENERAL HOSPITAL, MA$170,323MCBS
2024WNT Signaling in the Pathogenesis of Atrial Fibrillation1K08HL171874-01A1BAPAT, ANEESHMASSACHUSETTS GENERAL HOSPITAL, MA$169,974MCBS
2024Centralized Pain Management In Older Adult Cancer Survivors1K08AG081505-01A1SMITH, MICHAEL AUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$169,560AGCD
2024Mapping and modeling inhibitory interneurons in Alzheimer's disease and related dementias: novel strategies to reverse neural network dysfunction1K08AG084902-01A1CHEN, KEVIN SHOWENUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$169,560AGCD
2024Therapeutic Targeting of Transcription-Driven Epigenetic Defects in SF3B1 Mutant Myelodysplastic syndromes (MDS)1K08DK140636-01BODDU, PRAJWALYALE UNIVERSITY, CT$169,548DDK
2024DECIPHERING MECHANISMS OF IL-37 MEDIATED CONTROL OF PERIODONTAL INFLAMMATION1K08DE033494-01LIETZAN, ADAMUNIV OF NORTH CAROLINA CHAPEL HILL, NC$169,242DSR
2024Optimizing hematopoietic stem cell transplantation to treat non-malignant disease1K08HL168155-01A1PERSAUD, STEPHEN PHILLIPWASHINGTON UNIVERSITY, MO$169,156MCBS
2024Protective role of Endothelial Receptor Interacting Protein Kinase 3 (RIPK3) in acute lung injury1K08HL166958-01A1PRICE, DAVID REGANWEILL MEDICAL COLL OF CORNELL UNIV, NY$169,020MCBS
2024Practices of Foster Caregivers and the Developmental Outcomes of Youth in Foster Care: A Multi-Method Investigation1K08HD112700-01A1WRIGHT, ANNA WATERSVIRGINIA COMMONWEALTH UNIVERSITY, VA$168,818CHHD
2024Defining the role of NLRP3 inflammasome in clonal hematopoiesis1K08HL171879-01WONG, WAIHAY JBRIGHAM AND WOMEN'S HOSPITAL, MA$168,480MCBS
2024Etiology of naturally-occurring anti-ABO antibodies1K08HL171877-01JAJOSKY, RYAN PBRIGHAM AND WOMEN'S HOSPITAL, MA$168,480MCBS
2024Reducing Disparities in Mental and Metabolic Health among Predominantly Low-Income, Black and Hispanic Women with and without HIV1K08MD019998-01PEREZ, NICOLE BEAULIEUNEW YORK UNIVERSITY, NY$168,480ZMD1
2024Endoplasmic Reticulum Stress Controls Innate Lymphoid Cells in Intestinal Inflammation1K08DK140612-01CAO, SIYANWASHINGTON UNIVERSITY, MO$168,084DDK
2024Endothelial cell-based therapy for pulmonary vascular disease using induced pluripotent stem cells1K08HL173561-01HOLTZ, ALEXANDER MATTHEWBOSTON CHILDREN'S HOSPITAL, MA$167,940MCBS
2024Mural cells contribution to vascular remodeling in flow induced pulmonary hypertension1K08HL171843-01A1KLOUDA, TIMOTHYBOSTON CHILDREN'S HOSPITAL, MA$167,940MCBS
2024Risk-stratification and prediction of adverse outcomes in interstitial lung abnormalities1K08HL173562-01ROSE, JONATHANBRIGHAM AND WOMEN'S HOSPITAL, MA$167,410MCBS
2024Addressing Disparities in Out-of-Hospital Cardiac Arrest: Utilization of Health-Related Social Needs and Predictive Analytics to Improve Clinical Outcomes1K08HL169980-01A1ABBOTT, ETHANICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$167,383MCBS
2024Epithelial-immune interactions in neonates with Spontaneous Intestinal Perforation1K08DK133687-01A1OLALOYE, OLUWABUNMIYALE UNIVERSITY, CT$167,327DDK
2024Modulatory effects of a retinoid-related protein on intestinal endocrine cells1K08DK140637-01CALDERON, ROSSANA MCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$166,644DDK
2024Mechanisms of Complement Activation in Traumatic Injury1K08HL171936-01A1BARRETT, CHRISTOPHER DAVIDUNIVERSITY OF NEBRASKA MEDICAL CENTER, NE$166,644ZHL1
2024Digital Tools for Precision Nephrology1K08DK138280-01A1NESTOR, JORDAN GABRIELACOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$166,643DDK
2024Longitudinal Associations of Posttraumatic Stress Disorder with Incident Type 2 Diabetes and Poor Glycemic Control in a Large National Cohort1K08DK138296-01SERIER, KELSEY NICOLEBOSTON UNIVERSITY MEDICAL CAMPUS, MA$166,565DDK
2024Liquid biopsy cell-free DNA analysis to monitor sepsis1K08GM150038-01A1SEMENKOVICH, NICHOLAS PMEDICAL COLLEGE OF WISCONSIN, WI$166,204SAT
2024Exploiting neointimal and vascular smooth muscle cell heterogeneity to reveal mechanisms driving venous neointimal growth and vascular remodeling in pediatric pulmonary hypertension1K08HL173632-01STEFFES, LEASTANFORD UNIVERSITY, CA$165,996MCBS
2024Optimizing diabetes treatment strategies in complex comorbidity1K08DK137022-01A1LEITER, AMANDA CANDICEICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$165,714DDK
2024Moonlighting in Mitochondria: A Non-Canonical Role for Cardiac Troponin I in Inherited Cardiomyopathies1K08HL171896-01A1ELEZABY, ALYSTANFORD UNIVERSITY, CA$165,672MCBS
2024Multi-omic profiling of IPF endotypes1K08HL169926-01A1ZHANG, DACOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$165,405MCBS
2024Identifying metabolic regulation of T cells during early childhood development1K08HD109453-01A1ROWE, JARED H.DANA-FARBER CANCER INST, MA$165,240CHHD
2024Inflammatory Disease Associations in Clonal Hematopoiesis1K08HL171883-01A1WEEKS, LACHELLE DAWNDANA-FARBER CANCER INST, MA$165,080MCBS
2024The Role of E3 Ligase MARCH10 in Influenza Virus Infection1K08HL171895-01TSAI, MUCHUNOHIO STATE UNIVERSITY, OH$165,024MCBS
2024Using Bioinformatics Methodologies to Explore the Role of Short Interspersed Elements in the Pathogenesis of Idiopathic Inflammatory Myopathies1K08AR082939-01A1NAJJAR, RAYANUNIVERSITY OF WASHINGTON, WA$164,808AMS
2024Role of mTOR Hyperactivation in Pulmonary Vascular Remodeling1K08HL173620-01LIN, SUSAN MUNIVERSITY OF PENNSYLVANIA, PA$164,700MCBS
2024Determining the role of the creatine pathway regulation of intestinal goblet cell development in colitis1K08DK139375-01HALL, CAROLINE HUNIVERSITY OF COLORADO DENVER, CO$164,645DDK
2024The Unfolded Protein Response in Murine and Pediatric Cholestatic Liver Diseases1K08DK132456-01A1KRIEGERMEIER, ALYSSALURIE CHILDREN'S HOSPITAL OF CHICAGO, IL$164,452DDK
2024Endoplasmic Reticulum Protein Homeostasis in Renal Physiology and Acute Kidney Injury1K08DK136914-01A1PORTER, AIDANUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$164,040DDK
2024Modulation of Ventricular-Vascular Coupling in Veno-Arterial Extracorporeal Membrane Oxygenation1K08HL173696-01EVERETT, KAY D.TUFTS MEDICAL CENTER, MA$163,760MCBS
2024Transfer RNAs as novel mediators in acute lung injury1K08HL169725-01A1BEDNASH, JOSEPH STANLEYOHIO STATE UNIVERSITY, OH$163,620MCBS
2024Nanotransfection-based Cell Reprogramming to Drive Bone Revascularization in a Novel Mouse Model of Autogenous Cranioplasty1K08DE033142-01A1MITCHELL, KERRY-ANN STEWARTOHIO STATE UNIVERSITY, OH$163,620ZDE1
2024Biochemical Determinants of Chemokine Receptor Signaling1K08AR084617-01SMITH, JEFFREY SCOTTBRIGHAM AND WOMEN'S HOSPITAL, MA$163,514AMS
2024CD40 Immunotherapy Effect on the Cardiac Immune Landscape and Response to Myocardial Disease1K08HL163518-01A1JIMENEZ, JESUSWASHINGTON UNIVERSITY, MO$163,255MCBS
2024Multidimensional analysis of the regulatory T cell response in children with severe viral pneumonia1K08HL176208-01PRIGGE, ANDREWLURIE CHILDREN'S HOSPITAL OF CHICAGO, IL$163,080ZHL1
2024A comprehensive approach to understanding the genetic causes of urinary stone disease: combining monogenic and polygenic analyses1K08DK135933-01A1WU, CHEN-HAN WILFREDCASE WESTERN RESERVE UNIVERSITY, OH$163,036DDK
2024SREBP1 as a Novel Mammalian Oxygen Sensor1K08HL169915-01A1BAIK, ALAN HYUNUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$162,972MCBS

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