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NIH funding notice PAR-18-714

Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)

Closed on May 7, 2021.

Posted
March 14, 2018
Close date
May 7, 2021
Activity codes
R15
Institutes taking part
NCI, NEI, NHLBI, NHGRI, NIA, NIAAA, NIAID, NIBIB, NICHD, NCCIH, NIDCD, NIDCR, NIDDK, NIDA, NIEHS, NIGMS, NIMH, NINDS, NLM, NINR

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page names no earlier notice: it is new, or it does not say.

Replaced by PAR-21-155.

Who won it before

558 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $228,704,210 in first-year total cost, median $428,294.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 MDCN-R (86)]70
  2. Special Emphasis Panel[ZRG1 BST-F (80)]46
  3. Synthetic and Biological Chemistry A Study Section[SBCA]36
  4. Macromolecular Structure and Function A Study Section[MSFA]27
  5. Development - 2 Study Section[DEV2]24

Most frequent institutions

  1. BRIGHAM YOUNG UNIVERSITY13
  2. MICHIGAN TECHNOLOGICAL UNIVERSITY11
  3. UNIVERSITY OF ARKANSAS AT FAYETTEVILLE9
  4. STATE UNIVERSITY OF NY,BINGHAMTON8
  5. UNIVERSITY OF TOLEDO8
Competing awards under PAR-18-714 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2022Librational Mode Coupling Theory of Allosteric Signal Transmission1R15GM144870-01BEVERIDGE, DAVID LEWISWESLEYAN UNIVERSITY, CT$482,490MSFD
2022New Targets in C9orf72 FTD: Exploring Histone H3 S10 Phosphorylation1R15NS125394-01TORRENTE, MARIANA PLAZASBROOKLYN COLLEGE, NY$471,000ZRG1
2022Music as an autobiographical memory cue across the lifespan1R15AG075609-01BELFI, AMYMISSOURI UNIVERSITY OF SCIENCE & TECHNOLOGY, MO$462,163HCMF
2022Molecularly Targeted Probes for Photodynamic Therapy and Imaging of Breast Cancer1R15CA260420-01A1SCHMITTHENNER, HANS F.ROCHESTER INSTITUTE OF TECHNOLOGY, NY$457,717IPCA
2022The function of chromatin remodeling in the patterning of the salamander limb2R15HD092180-02MCCUSKER, CATHERINE DUNIVERSITY OF MASSACHUSETTS BOSTON, MA$457,500DEV2
2022Spermatogonial stem cell regulation and maintenance of male fertility1R15HD107594-01SIEGFRIED, KELLEE RUNIVERSITY OF MASSACHUSETTS BOSTON, MA$457,500CMIR
2022Role of semaphorin signaling in neuronal recovery from dendritic injury: a comparative case study in-vitro and in-vivo1R15NS125565-01HASPEL, GALTRAN, TRACY SNEW JERSEY INSTITUTE OF TECHNOLOGY, NJ$454,319ZRG1
2022Examining emotion regulation processes in social anxiety from an interpersonal and observational perspective1R15MH125289-01A1PETERS, BRETTZOCCOLA, PEGGY MYCEKOHIO UNIVERSITY ATHENS, OH$453,000SPIP
2022CofActor: Investigation of the Role of Cytoskeletal Dysregulation in Neurodegenerative Disease1R15NS125564-01HUGHES, ROBERT MEAST CAROLINA UNIVERSITY, NC$453,000ZRG1
2022Role of prolactin in adipocyte-breast cancer cell crosstalk1R15CA267923-01DIAKONOVA, MARIAUNIVERSITY OF TOLEDO, OH$451,500ZRG1
2022Association between workaholism and fasting glucose/insulin, insulin sensitivity, and lipids.1R15DK128608-01A1AZIZ, SHAHNAZEAST CAROLINA UNIVERSITY, NC$451,063KNOD
2022The Role of Hematopoietic Stem and Progenitor Cells in Solid Tumor Growth and Response to Radiation Therapy1R15CA254006-01A1MADLAMBAYAN, GERARD JAMESVILLA DIAZ, LUIS GERARDOOAKLAND UNIVERSITY, MI$449,795ZRG1
2022Identifying a proteomic signature for breast cancer detection in breast milk and serum1R15CA260126-01A1DARIE, COSTEL C.CLARKSON UNIVERSITY, NY$443,330ZRG1
2022Leisure as a Protective Factors against Everyday Risk for Cardiovascular Disease1R15HL161681-01ZAWADZKI, MATTHEW JASONUNIVERSITY OF CALIFORNIA, MERCED, CA$442,983SPIP
2022Nicotinamide nucleotide transhydrogenase and bioenergetic metabolism in complex I defective cardiac mitochondria1R15HL157838-01A1ROSCA, GEORGETA MARIANACENTRAL MICHIGAN UNIVERSITY, MI$439,500ZRG1
2022Evolved RNA Recognition Motifs for Therapeutic and Gene EditingApplications1R15GM141783-01MCNAUGHTON, BRIAN RICHARDDELAWARE STATE UNIVERSITY, DE$438,000MSFB
2022A Role for the Astrocytic Network in Spatial Navigation1R15AG075587-01BUHUSI, MONAUTAH STATE UNIVERSITY, UT$438,000ZRG1
2022Advanced Infrared Biology of Protein Structure & Dynamics1R15GM144898-01XIE, AIHUAOKLAHOMA STATE UNIVERSITY STILLWATER, OK$437,998MSFB
2022Molecular Structure of Chromium-DNA Adducts1R15ES033800-01VINCENT, JOHN BERTRAMWISE, JOHN PIERCEWOSKI, STEPHENUNIVERSITY OF ALABAMA IN TUSCALOOSA, AL$434,493MSFA
2022Autophagy mediated immune stimulation by reovirus in KRAS mutated colorectal cancer1R15CA267835-01MAITRA, RADHASHREEYESHIVA UNIVERSITY, NY$433,953ZRG1
2022Integrating population genomics and microbial metagenomics of the lone star tick, an expanding arthropod disease vector1R15AI159851-01A1MONZON, JAVIERPEPPERDINE UNIVERSITY, CA$428,341ZRG1
2022Investigation of Neuropeptide Signaling Mechanisms that Control Sleep2R15NS101692-02A1VECSEY, CHRISTOPHER GEORGE LORENZSKIDMORE COLLEGE, NY$427,433ZRG1
2022Telomere and telomerase evolution in S. cerevisiae1R15GM144954-01MEFFORD, MELISSA ANNEMOREHEAD STATE UNIVERSITY, KY$426,000ZRG1
2022DNA Base Detection Using 2D Materials Beyond Graphene1R15GM140445-01A1TAYO, BENJAMIN OBIUNIVERSITY OF CENTRAL OKLAHOMA, OK$425,928ZRG1
2022Mechanisms of Action of UmuD in Regulating DNA Damage-Induced Genes in a umuC-Deficient Bacterium2R15GM085722-04HARE, JANELLE MMOREHEAD STATE UNIVERSITY, KY$425,926ZRG1
2022Thyroid Hormone Receptor Mislocalization and Pathogenesis2R15DK058028-06ALLISON, LIZABETH ACOLLEGE OF WILLIAM AND MARY, VA$425,824ZRG1
2022Removing Barriers to Fluoride Varnish Application in Primary Care Settings1R15DE031428-01SCHERRER, CHRISTINAKENNESAW STATE UNIVERSITY, GA$423,574ODHS
2022GRip Assessment for Protocol Enhancements (GRAPE) in Older Adults1R15AG072348-01A1MCGRATH, RYANNORTH DAKOTA STATE UNIVERSITY, ND$416,481MFSR
2022A Causal Analysis of the Complex Mental Health Impacts of the Climate Crisis in Young People1R15ES033817-01RUNKLE, JENNIFER D.SUGG, MARGARET MAEAPPALACHIAN STATE UNIVERSITY, NC$413,598CIHB
2022DIVERSITY OF HUMAN MILK OLIGOSACCHARIDE METABOLIZING GENES IN TWO INFANT COHORTS1R15AI160139-01A1KLEPAC-CERAJ, VANJAWELLESLEY COLLEGE, MA$408,740KNOD
2022The role of metal ion homeostasis in regulating bacterial capsule production1R15AI149725-01A1MARTIN, JULIA E.IDAHO STATE UNIVERSITY, ID$408,497ZRG1
2022Targeted inhibition of stress associated pathways to promote resilience against maternal immune activation2R15MH114035-02KENTNER, AMANDAMCPHS UNIVERSITY, MA$383,006ZRG1
2022De Novo Mini-Metalloenyzmes with Hydrolase Activity1R15GM144906-01BUETTNER, KATHERINE MICHELLEREIG, AMANDAGETTYSBURG COLLEGE, PA$382,063MSFA
2022Biomarkers of Binge Drinking in Maltreated Adolescents1R15AA028911-01A1NOONER, KATE BRODYUNIVERSITY OF NORTH CAROLINA WILMINGTON, NC$379,503PDRP
2022Building Better Antioxidants: Virtual Screening, Synthesis, and Characterization of Multifunctional Small Molecules Combining Nrf2 Pathway Activation and Direct Antioxidant Activity2R15GM123463-02AKKARAJU, GIRIDHARCHUMLEY, MICHAEL JGREEN, KAYLA NJANESKO, BENJAMIN G.TEXAS CHRISTIAN UNIVERSITY, TX$379,063SBCA
2022Reducing Metal Artifacts in Clinical X-Ray CT via Image Reconstruction Techniques2R15EB024283-03ZENG, GENGSHENGUTAH VALLEY UNIVERSITY, UT$373,782ITD
2022Regulation of Hedgehog Signaling by new cilium proteins2R15CA235749-02GE, XUECAIUNIVERSITY OF CALIFORNIA, MERCED, CA$364,512DEV2
2022Tsc1 Regulation of Purkinje Neuron Firing and Cerebellar Function1R15NS125560-01RANSDELL, JOSEPH L.MIAMI UNIVERSITY OXFORD, OH$361,250ZRG1
2022Understanding the role of SPTBN1 in early steps of HIV-1 replication1R15AI157757-01HULME, AMY ELIZABETHMISSOURI STATE UNIVERSITY, MO$355,756HVCD
2022Chemoenzymatic synthesis of glycosylated and sulfated CCR5 N-terminal peptide library1R15GM144930-01ZHU, HAILIANG JOSHUADORDT COLLEGE, IA$350,916SBCA
2022Cellular effects of subway air particles in human lung cells1R15ES032588-01A1SHAKYA, KABINDRA MANVILLANOVA UNIVERSITY, PA$346,692SIEE
2022Signaling mechanisms underlying epilepsy and autism comorbidity2R15NS088776-03LUGO, JOAQUIN NBAYLOR UNIVERSITY, TX$343,235ZRG1
2022Prevention of alpha-synuclein deSUMOylation as a Parkinson's therapeutic target1R15NS121784-01A1KIM, YONGHWANDELAWARE STATE UNIVERSITY, DE$303,381ZRG1
2022Impact of Solute Carriers on Ruthenium Complex Sensitivity in Yeast1R15CA260456-01A1HANSON, PAMELAFURMAN UNIVERSITY, SC$299,191NCSD
2021Ensemble Networks for Allosteric Drug Design2R15GM128102-02THAYER, KELLY MARIEWESLEYAN UNIVERSITY, CT$492,900MSFD
2021Incorporation of newborn neurons in vocal learning1R15NS123921-01AARON, GLOSTERWESLEYAN UNIVERSITY, CT$489,336ZRG1
2021Elucidating Angular Protein Motion using Kinetic Ensemble Refinement1R15GM141974-01SMITH, COLIN ALEXANDERWESLEYAN UNIVERSITY, CT$483,702MSFD
2021Understanding how Connexin43 regulates joint formation in the regenerating zebrafish fin2R15HD080507-03IOVINE, MARY KATHRYNLEHIGH UNIVERSITY, PA$483,000ZRG1
2021Mechanisms and outcomes of the hyperglycemic shift to necroptosis in myeloid cells2R15HL135675-02LAROCCA, TIMOTHY JALBANY COLLEGE OF PHARMACY, NY$480,000ZRG1
2021Phenylboronic acid-based nanogels for onset-controllable glucose-regulated insulin delivery1R15DK127360-01A1ZHOU, SHUIQINCOLLEGE OF STATEN ISLAND, NY$476,249ZRG1
2021Undergraduate Research for Dose-Controllable Drug Delivery Implants1R15EY031500-01A1PARK, YOONJEEUNIVERSITY OF CINCINNATI, OH$474,519ZRG1
2021Biophysical Studies of Caveolin1R15GM141606-01GLOVER, KERNEY JEBRELLLEHIGH UNIVERSITY, PA$471,117BBM
2021SOCS domain-mediated fibronectin matrix degradation on fibrosis reversal1R15HL154051-01A1INGRAM, JANI CHERINORTHERN ARIZONA UNIVERSITY, AZ$469,034ZRG1
2021Mechanistic Investigation into Photoredox Catalysis1R15GM142103-01HIRSCHI, JENNIFERSTATE UNIVERSITY OF NY,BINGHAMTON, NY$465,870SBCB
2021Variant-specific dynamics of amyloid-b fibrils2R15GM111681-04VUGMEYSTER, LILIYAUNIVERSITY OF COLORADO DENVER, CO$463,077MSFB
2021Biomechanical factors affecting metatarsal fatigue and bone stress injury risk1R15HD104169-01A1TROY, KAREN LWORCESTER POLYTECHNIC INSTITUTE, MA$462,645ZRG1
2021Visualizing obesity-induced changes in dopamine reinforcement1R15DA052871-01A1BEELER, JEFF A.QUEENS COLLEGE, NY$462,000BRLE
2021Ethanolamine phospholipid synthesis in Leishmania1R15AI156746-01A1ZHANG, KAITEXAS TECH UNIVERSITY, TX$460,738ZRG1
2021Identifying and characterizing translation of circular RNAs using high-throughput sequencing data1R15GM140427-01PARK, JUW WONUNIVERSITY OF LOUISVILLE, KY$460,156MGA
2021Operation Mechanism of CLCF Fluoride/Proton Antiporter1R15GM141728-01LIN, HAIUNIVERSITY OF COLORADO DENVER, CO$459,584MSFD
2021Regulation of protein synthesis by metabolic signals and the circadian clock2R15GM129672-02VON ARNIM, ALBRECHT G.UNIVERSITY OF TENNESSEE KNOXVILLE, TN$459,000MIST
2021Application of autobioluminescence toward continuous and real-time in vitro/in vivo pre-clinical brain imaging for disease therapeutics1R15CA263826-01MILLET, LARRY J.UNIVERSITY OF TENNESSEE KNOXVILLE, TN$458,595ZRG1
2021Cell cycle regulation of polarity proteins in proliferating epithelia1R15GM141979-01RAGKOUSI, KATERINAAMHERST COLLEGE, MA$456,268NCSD
2021DO HEART FAILURE AND AGING POTENTIATE DIAPHRAGM VASCULAR DYSFUNCTION?1R15AG078060-01BEHNKE, BRAD JPOOLE, DAVID CKANSAS STATE UNIVERSITY, KS$456,000ZRG1
2021Are Minority Health Disparities in MRSA/MSSA Infections Related to Carriage and Social Relationships?1R15AI156771-01A1PEARSON, TALIMA ROSSNORTHERN ARIZONA UNIVERSITY, AZ$455,970ZRG1
2021Age-related changes in multi-behavioral reactive balance control1R15AG068935-01A1ALLEN, JESSICAWEST VIRGINIA UNIVERSITY, WV$455,956ZRG1
2021Targeting Dynamin-related protein 1-mediated mitochondrial fission to correct insulin resistance in obesity1R15DK131512-01ZOU, KAIUNIVERSITY OF MASSACHUSETTS BOSTON, MA$455,847CSME
2021Investigating functional development of neural circuits specified by the gs homeobox transcription factors in larval zebrafish1R15HD101974-01A1BERGERON, SADIE AWEST VIRGINIA UNIVERSITY, WV$455,337ZRG1
2021Prediction in Language Across the Lifespan1R15AG073948-01RYSKIN, RACHELUNIVERSITY OF CALIFORNIA, MERCED, CA$454,784LCOM
2021Development of Novel Metal-Based Supramolecular Therapeutics for Ovarian Cancer1R15CA249712-01A1ZHENG, YAORONGKENT STATE UNIVERSITY, OH$454,646SBCA
2021The Role of Macrophages in Immune Responses to Giardia2R15AI109591-03A1SINGER, STEVEN MGEORGETOWN UNIVERSITY, DC$453,551ZRG1
2021Novel Glycogen Synthase Kinase-3 (GSK-3) Inhibitors as Therapeutic Agents2R15GM110602-02GOETZ, DOUGLAS JOHIO UNIVERSITY ATHENS, OH$453,000MIST
2021Neuronal primary cilia and cognitive disorders1R15MH126317-01CHEN, XUANMAOUNIVERSITY OF NEW HAMPSHIRE, NH$451,526ZRG1
2021The Erk1/2-c-Fos/Egr1 Pathway in Neutrophil versus Monocyte Lineage Specification1R15HL156109-01DONG, FANUNIVERSITY OF TOLEDO, OH$451,500MCH
2021Regulation of Ferroptosis by the p53/CDK/Rb Axis.1R15GM141712-01TAYLOR, WILLIAM R.UNIVERSITY OF TOLEDO, OH$451,500MIST
2021Identification and Characterization of a Endogenous EGFR Regulatory Locus in Xiphophorus Genome2R15CA223964-02A1LU, YUANTEXAS STATE UNIVERSITY, TX$451,447ZRG1
2021ABHD5 Enzymatic Function and Role in Lipolysis1R15DK131627-01CAVIGLIA, JORGE MATIASBROOKLYN COLLEGE, NY$451,236CSME
2021NFkB-dependent antiviral pathways in VSV-resistant cancer cells1R15CA246419-01A1FERRAN, MAUREEN CROCHESTER INSTITUTE OF TECHNOLOGY, NY$451,178ZRG1
2021Deep Learning Methods to Integrate Biological Information for Analysis of Single-cell RNAseq Data1R15HG012087-01WEI, ZHINEW JERSEY INSTITUTE OF TECHNOLOGY, NJ$450,849BMRD
2021The role of lysine acetylation of human threonyl-tRNA synthetase1R15GM140433-01FAN, CHENGUANGUNIVERSITY OF ARKANSAS AT FAYETTEVILLE, AR$450,000MGA
2021Regulating Microtubule Severing Physically and Chemically1R15GM141722-01ROSS, JENNIFER LSYRACUSE UNIVERSITY, NY$450,000MSFC
2021Mechanisms of RNA binding proteins rescuing FUS induced toxicity in yeast1R15NS109804-01A1JU, SHULINWRIGHT STATE UNIVERSITY, OH$450,000ZRG1
2021Wnt signaling pathway interactions in early anterior-posterior specification and patterning2R15HD088272-03RANGE, RYAN CHRISTOPHERAUBURN UNIVERSITY AT AUBURN, AL$449,523DEV2
2021CDHR5 tumor suppressor function in the intestine1R15CA264735-01CRAWLEY, WILLIAM SCOTTUNIVERSITY OF TOLEDO, OH$449,218ZRG1
2021Mechanism of protocadherin-mediated self-avoidance1R15NS120155-01A1PHILLIPS, GREG RCOLLEGE OF STATEN ISLAND, NY$448,765ZRG1
2021Enzymatic Synthesis of Sugar-Derived Biosurfactants Using Multifunctional Ionic Liquids1R15GM143682-01KIM, SUNG JOONHOWARD UNIVERSITY, DC$448,706SBCB
2021Mechanistic basis for the low O2-dependent activity of a nicotine-degrading enzyme1R15GM139069-01A1STULL, FREDERICKWESTERN MICHIGAN UNIVERSITY, MI$448,682MSFA
2021Selenide-based electrocatalytic sensors for sensitive peroxynitrite detection in biological media: a bottom-up approach for functional interface design1R15GM140405-01A1BAYACHOU, MEKKICLEVELAND STATE UNIVERSITY, OH$447,128ZRG1
2021CCR6 as a Regulatory Switch for Epidermal gamma delta T Cell Function in Wound Repair1R15DK127440-01A1JAMESON, JULIE MCALIFORNIA STATE UNIVERSITY SAN MARCOS, CA$447,000ZRG1
2021Employing Metagenomic and Chromatin Capture Techniques to Map the Evolution of Antibiotic Resistance in Coastal Microbiomes1R15ES033027-01BECKET, ELINNE CORALCALIFORNIA STATE UNIVERSITY SAN MARCOS, CA$446,809ZRG1
2021Molecular mechanisms of metal-mediated biological functions for NO, O2, and HNO2R15GM085774-05ZHANG, YONGTHE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY, NJ$446,664MSFA
2021Development of the next-generation GPU-based Monte Carlo simulation platform for radiation-induced DNA damage calculations1R15CA256668-01A1CHI, YUJIEUNIVERSITY OF TEXAS ARLINGTON, TX$446,582ZRG1
2021Synergistic DNA repair genes and sensitivity to radiation therapy in prostate cancer1R15CA263784-01TOMIDA, JUNYAUNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$446,505ZRG1
2021Sterol Probes of Hedgehog Protein Processing1R15GM143714-01GINER, JOSE LCOLLEGE OF ENVIRONMENTAL SCI & FORESTRY, NY$445,995SBCB
2021A longitudinal study of self-regulation development: Effects of early life stress and impact on school-readiness1R15HD105179-01LAWLER, JAMIE MEASTERN MICHIGAN UNIVERSITY, MI$445,500MESH
2021Targeting Androgen Receptor-HSP27 Signaling in Glioblastoma1R15NS116766-01A1SU, BINCLEVELAND STATE UNIVERSITY, OH$445,500ZRG1
2021Positive and negative regulation of REC-8 cohesin during meiosis1R15GM143731-01SEVERSON, AARON FCLEVELAND STATE UNIVERSITY, OH$445,500CMIR
2021Development of Location-specific Sialidase Inhibitors1R15GM144881-01SUN, XUE-LONGCLEVELAND STATE UNIVERSITY, OH$445,500SBCA
2021Role of CD36 and diet-derived fatty acids in breast cancer1R15CA256838-01KUROKAWA, MANABUKENT STATE UNIVERSITY, OH$445,431ZRG1
2021Delivery of anti-fungal dsRNA into yeast and filamentous fungi using Laser-Activated Nanoparticles1R15GM144897-01AVILA FLORES, LUZ ADRIANAAUBURN UNIVERSITY AT AUBURN, AL$445,098ZRG1
2021Predicting tremor: Developing a validated, subject-specific model of tremor2R15NS087447-02CHARLES, STEVEN KNIGHTBRIGHAM YOUNG UNIVERSITY, UT$444,507MFSR
2021Conformational Flexibility of Lipoxygenases and its Role in Regulation and Substrate Acquisition.1R15GM143724-01GILBERT, NATHANIELLOUISIANA STATE UNIV A&M COL BATON ROUGE, LA$444,015MSFA
2021Using Established Leptin Signaling Mutants to Study Cell Physiology and Bone Development in Zebrafish1R15DK124790-01A1LIU, QINLONDRAVILLE, RICHARD LYLEUNIVERSITY OF AKRON, OH$443,905MCE
2021Redox-regulation in Gram-negative Bacteria1R15AI164585-01DAHL, JAN-ULRIKILLINOIS STATE UNIVERSITY, IL$443,840PCMB
2021Identifying an Atherogenic Role for Vascular Smooth Muscle Cell miR-33a Expression1R15HL152261-01A1STAMATIKOS, ALEXISCLEMSON UNIVERSITY, SC$443,688AICS
2021Isolation, identification and characterization of potentially novel antibiotics from rhizospheric bacteria without detectable in vitro resistance1R15GM144862-01HUDSON, ANDRE OROCHESTER INSTITUTE OF TECHNOLOGY, NY$443,583SBCB
2021Targeting oxidative stress-induced epigenetic reprogramming in fibrotic disease1R15DK121362-01A1SINGH, KAMALESHWAR PTEXAS TECH UNIVERSITY, TX$443,433PBKD
2021RNA-coupled Coenzymes1R15GM144859-01FRICK, DAVID NUNIVERSITY OF WISCONSIN MILWAUKEE, WI$442,896MSFA
2021J-Protein Regulation of Yeast Prion Propagation2R15GM110606-03HINES, JUSTIN KEITHLAFAYETTE COLLEGE, PA$442,683NCSD
2021Synergistic Upregulation of EpoR /RopE NPs for Enhancing Effective Angiogenesis to treat PAD1R15HL156076-01NGUYEN, KYTAI TRUONGUNIVERSITY OF TEXAS ARLINGTON, TX$442,549VCMB
2021Single-molecule approaches to study epiblast stem cell fate decision1R15GM140448-01A1CHOWDHURY, FARHAN HSOUTHERN ILLINOIS UNIVERSITY CARBONDALE, IL$442,500DEV2
2021Myelination Deficits Underlying Auditory Issues in Fragile X Syndrome1R15HD105231-01MCCULLAGH, ELIZABETH ANNEOKLAHOMA STATE UNIVERSITY STILLWATER, OK$442,099ZRG1
2021Calcium signaling controls Pseudomonas aeruginosa invasion and adaptation to the host intracellular environment2R15GM124670-02PATRAUCHAN, MARIANNA M. A.OKLAHOMA STATE UNIVERSITY STILLWATER, OK$441,822PCMB
2021Arsenic's effects on the intestinal stem cell niche1R15ES031766-01A1BAIN, LISA JCLEMSON UNIVERSITY, SC$441,662SIEE
2021Sex dependent function of the orphan nuclear receptor Nr4a1 in the pancreatic beta cell during Type 2 Diabetes disease progression1R15DK124835-01A1TESSEM, JEFFERY SIVERTBRIGHAM YOUNG UNIVERSITY, UT$441,165MCE
2021Strategy for Safe Colon-targeted Local Therapy of Inflammatory Bowel Disease1R15DK125940-01A1TUMMALA, HEMACHANDSOUTH DAKOTA STATE UNIVERSITY, SD$441,111XNDA
2021The Architecture of Missing and Archaic Variation in Human Population Genomic Data1R15GM143700-01AYERS, KIMBERLYCALIFORNIA STATE UNIVERSITY SAN MARCOS, CA$440,986GVE
2021Post translational modifications tune cardiac myosin1R15HL159585-01NESMELOV, YURIUNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$440,010MSFC
2021Genetic basis of metabolite production against clinically-derived pathogens2R15GM124585-02WILDSCHUTTE, HANSBOWLING GREEN STATE UNIVERSITY, OH$439,600ZRG1
2021Development of PDE5 Inhibitors for Localized Delivery to Prevent Colorectal Cancer1R15CA264555-01MIAO, SHAOBINAUGUSTA UNIVERSITY, GA$439,332ZRG1
2021Identifying the mechanism by which postpartum estrogen withdrawal impacts mesolimbic brain circuitry and motivated behaviors1R15MH125282-01A1BEEN, LAURA ELIZABETHHAVERFORD COLLEGE, PA$439,072ZRG1
2021Mechanisms of Delta-like 4 Endocytosis and Notch Activation During Blood Vessel Development1R15HL156106-01A1KUSHNER, ERICH JUNIVERSITY OF DENVER (COLORADO SEMINARY), CO$439,024ZRG1
2021Osiris Genes as Novel Coordinators of Protein Trafficking in Drosophila Trachea1R15GM140376-01A1JIANG, LANOAKLAND UNIVERSITY, MI$438,957DEV2
2021Identification of neuronal ensembles mediating fear generalization in the infralimbic cortex1R15MH127534-01BERGSTROM, HADLEY CREIGHTONVASSAR COLLEGE, NY$438,107ZRG1
2021Longitudinal Cognitive and Behavioral Testing and Immunohistochemical Assessment of Alzheimer's Disease Markers, Immune Response, Neurogenesis, and Cell Loss in a Natural Aging Primate Model2R15AG051940-02NEIWORTH, JULIE JCARLETON COLLEGE, MN$438,067CP
2021Speech Sound Perception and Production in Spanish/English Bilingual Preschoolers1R15DC019493-01MONTANARI, SIMONACALIFORNIA STATE UNIVERSITY LOS ANGELES, CA$438,000LCOM
2021Engineering of PPR base editors to repair pathogenic SNPs at the level of RNA1R15GM144905-01HAYES, MICHAEL LLOYDCALIFORNIA STATE UNIVERSITY LOS ANGELES, CA$438,000MSFB
2021Defining the molecular and cellular bases of tissue compartmentalization1R15GM143729-01PARE, ADAM CHRISTOPHERUNIVERSITY OF ARKANSAS AT FAYETTEVILLE, AR$437,147DEV2
2021THE ROLE OF HYDROGEN GAS IN HEALTH AND DISEASE1R15AG067470-01A1RADYUK, SVETLANA NIKOLAEVNASOUTHERN METHODIST UNIVERSITY, TX$437,142ZRG1
2021Nickel Catalyzed Electrochemical C-C Cross-Coupling Reactions1R15GM143721-01BAKER, MICHELLE A.UTAH STATE UNIVERSITY, UT$436,964SBCA
2021Regulation of choroid plexus epithelial function by klotho1R15AG073947-01KING, GWENDALYN DIANNCREIGHTON UNIVERSITY, NE$436,500ZRG1
2021Mechanisms of non-apoptotic programmed cell death and corpse clearance1R15GM143727-01WEHMAN, ANN MUNIVERSITY OF DENVER (COLORADO SEMINARY), CO$436,101NCSD
2021Investigation of ssDNA binding proteins and protein-ssDNA interactions1R15GM132846-01A1GUO, JUN-TAOUNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$435,894ZRG1
2021Insomnia phenotypes and their impact on maternal and infant health1R15HD102904-01A1OKUN, MICHELE LUNIVERSITY OF COLORADO, CO$434,654IRAP
2021Distinguishing features of C. albicans pseudouridylation and their roles in pathogenesis2R15AI130950-02A1BERNSTEIN, DOUGLAS A.BALL STATE UNIVERSITY, IN$433,183ZRG1
2021Fast Freezing Processes in Tissues1R15GM141653-01DEVIREDDY, RAMLOUISIANA STATE UNIV A&M COL BATON ROUGE, LA$432,803ZRG1
2021Adaptive evolutionary inference frameworks for understudied populations using generative neural networks1R15HG011528-01MATHIESON, SARAHAVERFORD COLLEGE, PA$432,494GVE
2021Early mechanisms mediating the organization of the axon initial segment impact the formation of axo-axonic synapses1R15NS124008-01HINES, ROCHELLE MARIEUNIVERSITY OF NEVADA LAS VEGAS, NV$431,046ZRG1
2021Studying the Gut-Brain inflammatory interaction1R15DK125941-01A1RHEE, SANG HOONOAKLAND UNIVERSITY, MI$430,646ZRG1
2021Chemical Tools for Delivery of Carbon Monoxide2R15GM124596-02BERREAU, LISA MUTAH STATE UNIVERSITY, UT$430,310SBCA
2021Socioecological approach to school start times and sleep health disparities in underrepresented youth1R15HD105153-01GUNN, HEATHER ELIZABETHUNIVERSITY OF ALABAMA IN TUSCALOOSA, AL$430,184CIHB
2021Cannabis Nexus Initiative: Cannabis and Heart Rate Variability Study in HBCU Students1R15DA052886-01A1KEEN, LARRY DVIRGINIA STATE UNIVERSITY, VA$430,014ARM
2021Bioengineering in vitro test beds to study fibrotic scar after spinal cord injury1R15NS121884-01SONG, YOUNGHYEUNIVERSITY OF ARKANSAS AT FAYETTEVILLE, AR$429,784ZRG1
2021Sympathetic regulation of inflammation from sleep fragmentation2R15GM117534-02ASHLEY, NOAH TODDWESTERN KENTUCKY UNIVERSITY, KY$429,768ZRG1
2021Autoantibody modulation of cartilage turnover in rheumatoid arthritis1R15AI154248-01A1FIELDS, GREGG BFLORIDA ATLANTIC UNIVERSITY, FL$429,189ZRG1
2021The Role of Anillins in Gradient Tracking1R15GM140409-01KELLEY, JOSHUA BRIANUNIVERSITY OF MAINE ORONO, ME$429,084NCSD
2021Virtual screening for the identification of ligands of GPR101, an orphan GPCR involved in X-linked acrogigantism (X-LAG)1R15GM141731-01COSTANZI, STEFANOAMERICAN UNIVERSITY, DC$429,000MIST
2021Investigating the Roles of APJ, Hypoxia, and SOX17 in the Development of Coronary Vessels1R15HL159660-01SHARMA, BIKRAMBALL STATE UNIVERSITY, IN$428,961BBHV
2021Myopalladin’s Role in Cardiac Muscle Function and Disease1R15GM140422-01A1BECK, MORIAH RWICHITA STATE UNIVERSITY, KS$428,473MSFC
2021Minimal Protein Affinity Tags1R15GM141708-01URBACH, ADAM ROBERTTRINITY UNIVERSITY, TX$428,303SBCA
2021Uncovering Synthetic Potential of Distonic Radical Cations1R15GM144874-01ZHENG, NANUNIVERSITY OF ARKANSAS AT FAYETTEVILLE, AR$427,507SBCA
2021The effects of depleted uranium shrapnel on mitochondrial cellular function.1R15ES032923-01SALANGA, MATTHEWNORTHERN ARIZONA UNIVERSITY, AZ$427,265SIEE
2021Sex Differences in the Neurobiological Significance of Orexin Stress Signaling1R15MH125306-01A1SUMMERS, CLIFF HUNIVERSITY OF SOUTH DAKOTA, SD$427,255ZRG1
2021Structural Flexibility Mediates Circadian Adaptation in Diverse Organisms2R15GM109282-03ZOLTOWSKI, BRIAN DAVIDSOUTHERN METHODIST UNIVERSITY, TX$425,609MSFD
2021Discovery and Characterization of Novel Halogenases from the Human Microbiome1R15GM144877-01BELLIZZI, JOHN J.UNIVERSITY OF TOLEDO, OH$424,735MSFA
2021Renewal: Terahertz Polarization Imaging for Detecting Breast Tumor Margins2R15CA208798-02A1EL-SHENAWEE, MAGDAUNIVERSITY OF ARKANSAS AT FAYETTEVILLE, AR$424,545ZRG1
2021The role of copines in the regulation of the actin cytoskeleton and membrane trafficking2R15GM078089-03DAMER, CYNTHIA KCENTRAL MICHIGAN UNIVERSITY, MI$424,082NCSD
2021Determining the role of DNA methylation in the tissue-specific expression of the Na,K-ATPase-Na/H exchanger pH regulatory system genes.1R15HD101985-01A1JAMES, PAUL FMIAMI UNIVERSITY OXFORD, OH$423,293CMIR
2021Exploring the role of mitochondria in dysregulated calcium handling in diseased hearts1R15HL154073-01A1LIU, BINMISSISSIPPI STATE UNIVERSITY, MS$422,652ZRG1
2021Patient Genetic Determinants of Chronic Wound Microbiome Composition1R15GM141973-01PHILLIPS, CALEB DAKOTAHTEXAS TECH UNIVERSITY, TX$421,373IRAP
2021Development of a new computational method for predicting drug - target interactions using a TSR-based representation of 3-D structures1R15GM144944-01XU, WUUNIVERSITY OF LOUISIANA AT LAFAYETTE, LA$420,456MSFD
2021Calcium Binding Proteins Regulate Susceptibility to Damage in the Inner Ear1R15DC018935-01A1SIMMONS, DWAYNE DBAYLOR UNIVERSITY, TX$420,000ZRG1
2021Decoding the Role of Bacterial Outer Membrane Vesicle and Small RNAs in Host Inflammation1R15AI156742-01A1GREATHOUSE, LEIGHBAYLOR UNIVERSITY, TX$420,000ZRG1
2021De novo designed metalloproteins as a new generation of artificial hydrogenases2R15GM131260-02CHAKRABORTY, SAUMENUNIVERSITY OF MISSISSIPPI, MS$419,483MSFA
2021A Chemical Strategy of Developing Resistance-Proof, Immune-Friendly Drugs1R15CA253069-01A1BANERJEE, PROBALCOLLEGE OF STATEN ISLAND, NY$418,748ZRG1
2021Biomimetic models of manganese- and iron-histidine coordination sites in metalloproteins for chelation, antibiotic activity, and oxidative reactivity1R15GM143702-01CREUTZ, SIDNEY EMISSISSIPPI STATE UNIVERSITY, MS$418,017MSFA
2021Nucleic Acid Nanoparticle-based Monoclonal Antibody Mimics1R15EB031388-01KHISAMUTDINOV, EMILBALL STATE UNIVERSITY, IN$417,416ZRG1
2021CONSTRUCTING A HIGH-RESOLUTION GENE REGULATORY NETWORK OF EMT1R15GM139113-01A1WARNER, JACOB FUNIVERSITY OF NORTH CAROLINA WILMINGTON, NC$415,850DEV2
2021Nickel-Catalyzed Alkyne Hydroamination for Efficient Amine Synthesis1R15GM143712-01ZHAO, PINJINGNORTH DAKOTA STATE UNIVERSITY, ND$414,750SBCA
2021Biochemical characterization of a novel Fragile X Mental Retardation Protein nuclease function2R15GM127307-05MIHAILESCU, MIHAELA RDUQUESNE UNIVERSITY, PA$414,000ZRG1
2021Androgen signaling and sterol metabolism in metastatic prostate cancer: Functional and therapeutic implication1R15CA252997-01A1SHUKLA, GIRISH CCLEVELAND STATE UNIVERSITY, OH$412,416ZRG1
2021An Experimental Approach to Emotion Regulation: Investigating Rumination, Cognitive Control, and Maladaptive Behaviors.1R15MH122937-01A1DESHONG, HILARY LEAMISSISSIPPI STATE UNIVERSITY, MS$412,355APDA
2021Metabolic control of porphyrin biosynthesis by mTOR signaling1R15DK127370-01PELLETTIERI, JASONKEENE STATE COLLEGE, NH$412,148XNDA
2021Investigating the regulation of PI(3,4)P2 in migrating cells1R15GM143733-01EDWARDS, MARCAMHERST COLLEGE, MA$411,565NCSD
2021Mechanisms of cardiomyocyte-extracellular matrix interactions in cardiogenesis1R15HD106256-01SCHUMACHER, JENNIFERMIAMI UNIVERSITY OXFORD, OH$411,542ZRG1
2021Target-specific inhibition and activation of protein tyrosine phosphatases2R15GM071388-05A1BISHOP, ANTHONY CAMHERST COLLEGE, MA$411,330SBCB
2021Cell-type and projection-specific dissection of the bed nucleus of the stria terminalis in the mediation of social behavioral deficits induced by early life adversity1R15MH127514-01HALLADAY, LINDSAY RENEESANTA CLARA UNIVERSITY, CA$411,000ZRG1
2021Biocompatible Graphene Quantum Dots for Noninvasive Near-infrared Bioimaging1R15EB031528-01NAUMOV, ANTONWORMLEY, FLOYD L.TEXAS CHRISTIAN UNIVERSITY, TX$410,136ZRG1
2021The role of PAM-1 in the regulation of the cell cycle and polarity establishment in C. elegans2R15GM110614-03LYCZAK, REBECCA LYNNURSINUS COLLEGE, PA$407,883DEV2
2021Identification and functional analysis of A-tubule MIPs1R15GM143703-01BAYLESS, BRIAN ANTHONYSANTA CLARA UNIVERSITY, CA$407,661NCSD
2021Bystander Intervention for Problematic Alcohol Use Measure (BIPAUM) to Reduce Risky Drinking among Diverse College Students1R15AA028910-01MENNICKE, ANNELISEMONTANARO, ERIKA ANNUNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$407,249SPIP
2021Impacts of parental benzo[a]pyrene exposure on offspring’s bone development1R15ES032936-01SEEMANN, FRAUKETEXAS A&M UNIVERSITY-CORPUS CHRISTI, TX$405,202SIEE
2021Understanding the role of the conserved KIN-20 protein in regulating gene expression and development in C. elegans1R15HD104101-01VAN WYNSBERGHE, PRISCILLACOLGATE UNIVERSITY, NY$404,572DEV2
2021Mechanism-Based Design of Iron-Mediated Carbonyl-Olefin Metathesis Protocols2R15GM128126-02DEVERY, JAMES JOHNLOYOLA UNIVERSITY OF CHICAGO, IL$403,593MSFA
2021Regulation of Collagen Type I Expression by Chaperone-Mediated mRNA Remodeling1R15GM141770-01BAGGS, ERICBOISE STATE UNIVERSITY, ID$402,174MSFC
2021Regulation of Substrate Binding in the bc1 Complex1R15GM141975-01KOKHAN, OLEKSANDRJAMES MADISON UNIVERSITY, VA$402,105MSFA
2021Deciphering Helicobacter pylori's glycocode: uncovering and harnessing drug targets2R15GM109397-03DUBE, DANIELLE H.BOWDOIN COLLEGE, ME$400,669SBCA
2021Carboxylic Acid Receptors in Mosquitoes1R15AI156684-01PITTS, RONALD JASONBAYLOR UNIVERSITY, TX$400,583ZRG1
2021Inteins: Expanding Biological Roles and Biotechnological Applications1R15GM143662-01LENNON, CHRISTOPHER WILLIAMMURRAY STATE UNIVERSITY, KY$399,185MSFB
2021Exploring the Dynamics of Prolyl-tRNA Synthetases: Towards Developing a Screening Method for Species-Specific Inhibitors2R15GM117510-02BHATTACHARYAY, SUDEEPHATI, SANCHITAUNIVERSITY OF WISCONSIN EAU CLAIRE, WI$397,331MSFB
2021Brain-Computer Interface in dynamic tasks with deep learning and functional connectivity analysis1R15NS118581-01A1CECOTTI, HUBERT CHARLESCALIFORNIA STATE UNIVERSITY FRESNO, CA$396,731HCMF
2021Assessing Ligand vs Ligandless Catalysis to Simplify Chemical Transformations and Drug Discovery1R15GM141726-01BUGARIN, ALEJANDROFLORIDA GULF COAST UNIVERSITY, FL$396,626SBCB
2021Stereoselective Synthesis of Biologically Relevant Heterocycles via Brønsted Acid Catalysis1R15GM141981-01PETERSEN, KIMBERLY SUEUNIVERSITY OF NORTH CAROLINA GREENSBORO, NC$396,040SBCA
2021Neurobiology of female sexual health1R15HD104100-01A1MEERTS, SARAHCARLETON COLLEGE, MN$395,861ZRG1
2021Engineering novel designer biologics in plant cells for oral treatment of ulcerative colitis1R15DK128757-01XU, JIANFENGARKANSAS STATE UNIVERSITY, AR$395,242ZRG1
2021Biomimetic cytoskeleton and advanced microscopy to reveal intracellular DNA dynamics and distributions2R15GM123420-02MCGORTY, RYANROBERTSON-ANDERSON, RAE MARIEUNIVERSITY OF SAN DIEGO, CA$395,086ZRG1
2021A data analytics framework for the application of pedestrian dynamics to public health1R15LM013382-01A1NAMILAE, SIRISHEMBRY-RIDDLE AERONAUTICAL UNIVERSITY, FL$394,525BMRD
2021Metallopeptide Based Mimics of Mononuclear Nonheme Iron Enzymes: Understanding Enzymatic Reactivity Using Designed Metallopeptides1R15GM141650-01SHEARER, JASON MTRINITY UNIVERSITY, TX$394,366MSFA
2021Design and construct modular transcriptional repressors to facilitate the development of living diagnostics1R15GM135813-01CHAN, TSZ YAN CLEMENTUNIVERSITY OF NORTH TEXAS, TX$391,722ZRG1
2021Uncovering the Mechanistic Role of DNA Pol Theta in UV-Damage Repair1R15GM144903-01TOWLE-WEICKSEL, JAMIE B.RHODE ISLAND COLLEGE, RI$391,569ZRG1

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