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NIH funding notice PAR-21-155

Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)

Closed on May 7, 2024.

Posted
May 19, 2021
Close date
May 7, 2024
Activity codes
R15
Institutes taking part
NIGMS, NEI, NHGRI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIDA, NIEHS, NIMH, NINDS, NINR, NLM, NCCIH, NCI, NHLBI

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PAR-18-714 Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)

Replaced by PAR-24-152.

Who won it before

1,178 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $488,549,587 in first-year total cost, median $430,235.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 MDCN-R (86)]95
  2. Macromolecular Structure and Function A Study Section[MSFA]58
  3. Synthetic and Biological Chemistry A Study Section[SBCA]50
  4. Special Emphasis Panel[ZRG1 BST-F (80)]46
  5. Macromolecular Structure and Function B Study Section[MSFB]42

Most frequent institutions

  1. MICHIGAN TECHNOLOGICAL UNIVERSITY30
  2. BRIGHAM YOUNG UNIVERSITY27
  3. UNIVERSITY OF NORTH CAROLINA CHARLOTTE20
  4. UNIVERSITY OF TOLEDO19
  5. MIAMI UNIVERSITY OXFORD18
Competing awards under PAR-21-155 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025R15: Enhancement of Genome Editing in Hematopoietic Stem Cells by Nucleic Acids Nanoparticles Delivery of CRISPR/CAS System1R15HL177745-01FU, JINGLINRUTGERS THE STATE UNIV OF NJ CAMDEN, NJ$486,291ZRG1
2025Synthesis and Exploration of Highly Fluorescent Thiazolothiazole Molecular Sensors for Probing Membrane Potential Dynamics2R15GM140392-02WALTER, MICHAEL G.UNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$476,534CBP
2025Development of novel, daptomycin-inspired antimicrobial peptides using non-canonical amino acids1R15AI188560-01CAPUTO, GREGORY ALEXANDERROWAN UNIVERSITY, NJ$474,363DMPA
2025Coordinating cellular events during spore development2R15GM086805-05A1HUANG, LINDA S.UNIVERSITY OF MASSACHUSETTS BOSTON, MA$464,083ZRG1
2025cAMP signaling and three activity states of hippocampal neurons2R15MH125305-02CHEN, XUANMAOUNIVERSITY OF NEW HAMPSHIRE, NH$460,500NC
2025Investigating NEK10 as a myosin light chain kinase1R15GM157662-01CRAWLEY, WILLIAM SCOTTUNIVERSITY OF TOLEDO, OH$458,998ZRG1
2025Dissecting the mechanisms through which Wnt5 signaling influences hematopoiesis1R15HL177689-01GIRARD, JULIETUNIVERSITY OF MASSACHUSETTS BOSTON, MA$457,500ZRG1
2025Control of Polarized Basement Membrane Secretion in Epithelial Cells2R15GM137236-02DEVERGNE, OLIVIERNORTHERN ILLINOIS UNIVERSITY, IL$455,997ZRG1
2025Mechanisms of Peripheral Nerve Injury and Recovery in a Zebrafish Demyelination Model1R15NS141049-01PETERSEN, SARAHKENYON COLLEGE, OH$454,424CMBG
2025FGFR1 Signaling in AgRP Neurons for Regulating Metabolism1R15DK139539-01A1HUANG, HUEAST CAROLINA UNIVERSITY, NC$453,000BMDM
2025High-throughput Identification and Validation of Drugs to Target Migrating and Treatment-Resistant Glioblastoma Cells1R15CA290638-01A1KIM, YOUNG-TAEUNIVERSITY OF TEXAS ARLINGTON, TX$451,996ZRG1
2025VS-EDGE: Visual-Semantic Explanations for Diagnostic Guidance1R15CA297521-01RAICU, DANIELA STANDE PAUL UNIVERSITY, IL$449,595EITA
2025Calcium regulation and outer hair cell sensitivity to cochlear injury1R15DC022073-01SIMMONS, DWAYNE DBAYLOR UNIVERSITY, TX$448,687AUD
2025Structure, Function, and Dynamics of Non-Canonical Stress Granules1R15GM157697-01FARNY, NATALIE GILKSWORCESTER POLYTECHNIC INSTITUTE, MA$445,873ZRG1
2025ENHANCEMENT OF BBB CROSSING OF AR DEGRADERS IN GBM2R15NS116766-02SU, BINCLEVELAND STATE UNIVERSITY, OH$445,500ZRG1
2025Chemoenzymatic Semisynthesis of Proteoglycan and Its Cofactor Activities1R15HL177621-01SUN, XUE-LONGCLEVELAND STATE UNIVERSITY, OH$445,500CSB
2025Novel mitochondria-targeting peptides (MTPs) as therapeutic intervention in Barth syndrome1R15HL177692-01SANDLERS, YANA ICLEVELAND STATE UNIVERSITY, OH$445,500ZRG1
2025A Spatial and Temporal Analysis of MCH Signaling in the Developing Adipocyte1R15GM157665-01COOK, LAURIE BCOLLEGE AT BROCKPORT, NY$442,397ZRG1
2025Multiscale anisotropy analysis of breast tissue subtypes from mammography and pathology2R15CA246335-02KHALIL, ANDREUNIVERSITY OF MAINE ORONO, ME$440,561ZRG1
2025Signal-dependent regulation of cardiac progenitor proliferation1R15HL173851-01A1DAVIDSON, BRADLEY JSWARTHMORE COLLEGE, PA$439,065ZRG1
2025PTEN and gut epithelial physiology1R15CA297583-01RHEE, SANG HOONOAKLAND UNIVERSITY, MI$439,049DNPD
2025Mechanophenotyping RBC subpopulations in ME/CFS1R15HL177762-01RAMASUBRAMANIAN, ANAND KSAN JOSE STATE UNIVERSITY, CA$432,431ZRG1
2025RTA-Induced Ubiquitination in KSHV: A CURE-Based Approach to Identify Novel Targets and Small Molecule Inhibitors1R15AI186824-01A1EHRLICH, ELANA STOWSON UNIVERSITY, MD$430,285HCAC
2025Dissecting inflammatory outcomes following eCigarette exposure2R15HL152257-02REYNOLDS, PAUL RBRIGHAM YOUNG UNIVERSITY, UT$428,639ZRG1
2025Accessing Carbon-based S(VI) compounds via Sulfur-Fluorine (SuFEx) Exchange Reactions2R15GM134457-02BALL, NICHOLAS DPOMONA COLLEGE, CA$428,004CSB
2025Role of the parasubthalamic nucleus (PSTN) in the central regulation of feeding behavior1R15DK142148-01CARTER, MATTHEW EWILLIAMS COLLEGE, MA$427,000NIC
2025Rational Design of Artificial Hydrogenases2R15GM131260-03CHAKRABORTY, SAUMENUNIVERSITY OF MISSISSIPPI, MS$426,202MSFA
2025Cannabis Nexus Initiative II: Cannabis and Heart Rate Variability Study in HBCU Students2R15DA052886-02KEEN, LARRY DVIRGINIA STATE UNIVERSITY, VA$420,388ARM
2025An investigation of hyperglycemia-induced region-specific changes in brain metabolism and behavior1R15MH139024-01VICHAYA, ELISABETH GOODBAYLOR UNIVERSITY, TX$420,000PMDA
2025Type 1 Diabetes: Dyadic Health Behaviors and Communal Coping as Predictors of Glycemic Control Among Emerging Adult Couples1R15DK142163-01YORGASON, JEREMY B.BRIGHAM YOUNG UNIVERSITY, UT$419,750CMGC
2025Detecting Fatigue and Assessing Cognitive Performance in Video-Based Meetings: Integration of Lab, Field, and Machine Learning Approaches1R15MH135412-01A1BARUAH, JONALIKALITA, JUGALTARLETON STATE UNIVERSITY, TX$419,534HCMF
2025Prepare Bioanalytical Aptamer Tools and Train Next-generation Scientists for SARS-CoV-31R15AI183190-01A1TAN, XIAOHONGBOWLING GREEN STATE UNIVERSITY, OH$419,466CBP
2025Enhancing the Force Validated Heart Valve Surgical Planning Tool1R15HL177711-01JENSEN, MORTEN OLGAARDUNIVERSITY OF ARKANSAS AT FAYETTEVILLE, AR$414,982ZRG1
2025Evaluating the effect of physical activity on sleep disruption and subclinical cardiovascular disease risk in peri- and early postmenopausal women.2R15HL145650-02A1WITKOWSKI, SARAHSMITH COLLEGE, MA$408,656ZRG1
2025Dual localization of angiopoietin like protein 4 in the extracellular milieu and nucleus regulates the hematogenous brain metastasis of triple negative breast cancer1R15CA287303-01A1BAILEY, TAMEKA ARNETTARKANSAS STATE UNIVERSITY, AR$408,259ZRG1
2025Examining the mediating and moderating factors in the relationships between social media engagement and ENDS use and dependence among young adults1R15CA290615-01A1YANG, QINGHUATEXAS CHRISTIAN UNIVERSITY, TX$407,581LHB
2025Investigation of the Properties of Liquids in the Porous Networks of Macromolecular Crystals2R15GM090248-03JUERS, DOUGLAS HENRYWHITMAN COLLEGE, WA$404,329MSFB
2025Expression of High-Activity and High-SpecificityMicrobial L-Asparaginases from Naturally Occurring Microorganisms in the Alabama Black Belt1R15GM154270-01A1OKEKE, BENEDICT CAUBURN UNIVERSITY AT MONTGOMERY, AL$403,640CSB
2025Genetic Regulation of Stress Responses at the Endoplasmic Reticulum1R15GM157704-01DAHLBERG, CAROLINE LUNDWESTERN WASHINGTON UNIVERSITY, WA$401,429ZRG1
2025Optimization of cannabidiol-based formulations in autism spectrum disorder1R15NS141197-01KAPLAN, JOSHWESTERN WASHINGTON UNIVERSITY, WA$396,988DBD
2025Cellular mechanisms of forgetting a long-term memory2R15MH107892-03CALIN-JAGEMAN, IRINA ELENACALIN-JAGEMAN, ROBERT JOSEPHDOMINICAN UNIVERSITY, IL$392,062LMDN
2025Identifying social computational phenotypes in mental health1R15MH138992-01STANLEY, DAMIAN ALEXANDERADELPHI UNIVERSITY, NY$388,026APDA
2025Synthesis and Pharmacological Evaluation of 5-Hydroxy-2-(2- phenylethyll)chromone Analogues1R15GM157720-01WILLIAMS, DWIGHT AKALAMAZOO COLLEGE, MI$384,609CBP
2025A mechanistic approach to understand the tissue-specific development of toxicity in response totransgenerational chronic arsenic exposures1R15ES037123-01ROY CHOWDHURY, PRIYANKAKEENE STATE COLLEGE, NH$379,504EDD
2025Redox Properties and Partners of the Yeast Thioredoxin Reductase Trr11R15GM151680-01A1WEST, JAMES DCOLLEGE OF WOOSTER, OH$316,797MSFA
2025Mechanisms and Consequences of Nucleic Acid Sensing in Erythroid Progenitors1R15AI188361-01CLEMENTS, REBECCA LYNNSWARTHMORE COLLEGE, PA$74,108BBHV
2024Phospholipid metabolism in Leishmania2R15AI156746-02ZHANG, KAITEXAS TECH UNIVERSITY, TX$498,722PTHE
2024Investigating the role of helix-1 in the fibrillization of SAA1-761R15GM155857-01DESAMERO, RUEL Z BYORK COLLEGE, NY$496,648MSFB
2024ELUCIDATING THE FUNCTION OF P53-MEDIATED IL17RB REPRESSION1R15CA287406-01ZHU, YANST. JOHN'S UNIVERSITY, NY$492,000ZRG1
2024Novel pseudo-differential methods to drastically increase computational speed and accuracy for biomedical ultrasound imaging and focusing1R15EB035359-01A1KHAJAH, TAHSINUNIVERSITY OF TEXAS TYLER, TX$481,440ITD
2024Repression of inflammasome by Francisella tularensis2R15AI107698-04MALIK, MEENAKSHIALBANY COLLEGE OF PHARMACY, NY$480,000ZRG1
2024Probiotic neuroimmune modulation of morphine tolerance1R15DA058187-01A1WHISTLER, CHERYL ALLYNEUNIVERSITY OF NEW HAMPSHIRE, NH$479,535ZRG1
2024Development of Tailored, Multilevel Cervical Cancer Interventions for Ethnically Diverse Black Women1R15CA294297-01AMUTA, ANN OYAREUNIVERSITY OF TEXAS ARLINGTON, TX$477,869HHD
2024The effects of biological sex, intolerance of uncertainty and anxious states on threat acquisition and extinction learning1R15MH134219-01A1JOHNSON, DAVID CHARLESYORK COLLEGE, NY$475,572APDA
2024Implicating the major G-quadruplex helicase, DHX36, as a novel pathogenic modifier of C9ORF72 frontal temporal dementia2R15AG067291-02SMALDINO, PHILIP JBALL STATE UNIVERSITY, IN$475,516CMND
2024Attention and memory contributions to the maintenance of binge eating1R15MH137623-01JOHNSON, JEFFREY SCOTTNORTH DAKOTA STATE UNIVERSITY, ND$470,808APDA
2024BITE (Bat Immunology Training and Education) - an undergraduate experiential program for developing the next generation of One Health scientists1R15AI180994-01THOMPSON, CODY WELFORDWHITE III, RICHARD ALLENUNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$470,518CMIA
2024The Role of HA Remodeling and Mesenchymal Transitions in Glioblastoma1R15CA274344-01A1CHEN, JOSEPHUNIVERSITY OF LOUISVILLE, KY$469,500ZRG1
2024Mitochondrial-targeting Exosomes for Neuroinflammation1R15EB035866-01BI, LANRONGMICHIGAN TECHNOLOGICAL UNIVERSITY, MI$469,500ZRG1
2024Modulation of host chromatin dynamics and gene expression by viral biomolecular condensates1R15AI183280-01MAY, JARED PAULUNIVERSITY OF MISSOURI KANSAS CITY, MO$469,500VDT
2024Cell-cell signaling and pattern formation in yeast1R15GM154311-01A1HONIGBERG, SAUL MUNIVERSITY OF MISSOURI KANSAS CITY, MO$469,500ZRG1
2024Investigation of Molybdenum Cofactor through Chemical, Biochemical and Biophysical Studies2R15GM139064-02BASU, PARTHAINDIANA UNIVERSITY INDIANAPOLIS, IN$469,170MSFA
2024Mechanoregulation of E-cadherin Adhesion2R15GM116082-03MARUTHAMUTHU, VENKATOLD DOMINION UNIVERSITY, VA$468,958ZRG1
2024Improving Artificial Intelligence Readiness of RNA Motif Data for Structure Analysis and Modeling1R15GM155891-01HOU, JIESAINT LOUIS UNIVERSITY, MO$467,334MSFB
2024Body heat activated, storable, near-infrared, self-illuminating nanoprobes for chemiluminescence imaging of cancer1R15DE034720-01A1LEE, JUNG-JAEUNIVERSITY OF COLORADO DENVER, CO$466,500IPCA
2024Understanding cell chirality and cell-cell interactions at neurovascular unit after brain injury1R15NS139138-01ZHANG, ZHIUNIVERSITY OF MICHIGAN AT DEARBORN, MI$465,752CMBG
2024Chaperoning Preassembly Modules for Mitochondrial Ribosome Assembly1R15GM155795-01HENRY, MICHAELROWAN UNIVERSITY, NJ$463,083ZRG1
2024Functional Hybrid Natural Product Synthases by Tracking Acyl Carrier Protein Binding and Conformational Dynamics2R15GM120704-03CHARKOUDIAN, LOUISE KARINEHAVERFORD COLLEGE, PA$462,351MSFA
2024Neuroprotection for chemotherapy induced peripheral neuropathy1R15CA290570-01YANG, IN HONGUNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$462,000NOMD
2024A Single-Sided Magnetic Particle Imaging Scanner for In Vivo Breast Cancer Imaging2R15EB028535-03TONYUSHKIN, ALEXEY AOAKLAND UNIVERSITY, MI$461,895ITD
2024Using Event Momentary Assessment and Actigraphy to Investigate Mediating and Moderating Processes of Discrimination's Negative Effect onSleep1R15HL172210-01A1KUNSTMAN, JONATHANAUBURN UNIVERSITY AT AUBURN, AL$460,920MESH
2024Determining the impact of cargo membrane fluidity on motor protein function2R15GM120682-03XU, JINGUNIVERSITY OF CALIFORNIA, MERCED, CA$460,552BBM
2024Utilizing Bioprinted Human Stem Cells for Molecular Screening via Multi-Material Strategies1R15EB036822-01SUH, WON HYUKUNIVERSITY OF NEW HAMPSHIRE, NH$460,500ZRG1
2024Enhancing Vaccine Thermostability with Natural Deep Eutectic Solvents1R15GM153057-01MIRJAFARI, ARSALANCOLLEGE AT OSWEGO, NY$459,551ZRG1
2024Distributed approaches to train machine learning models in diabetic retinopathy1R15EY035804-01ALAM, MINHAJ NURUNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$459,516CDMA
2024Improving Image-Guided Surgery Precision and Reliability with Real-time Modification Tracking in Endoscopic Sinus and Skull Base Surgery1R15EB034519-01A1LEE, YANGMINGROCHESTER INSTITUTE OF TECHNOLOGY, NY$459,375IGIS
2024Discovery of Novel Cyanotoxins by Detection of Their Native Fluorescence and Unique MS/MS Fragments, and Determination of Their Toxicities1R15ES036709-01ISAILOVIC, DRAGANUNIVERSITY OF TOLEDO, OH$459,353ZRG1
2024Understanding the role of molecular chaperone systems in protein aggregate disassembly1R15GM155860-01MANOGARAN, ANITA L.MARQUETTE UNIVERSITY, WI$459,006ZRG1
2024Socioeconomic impacts of La Crosse encephalitis in western North Carolina1R15AI183269-01BYRD, BRIAN DAVIDRICHARDS, STEPHANIE LYNNEAST CAROLINA UNIVERSITY, NC$458,992PRID
2024Neural Mechanisms Underlying Central Induction of Skeletal Muscle Thermogenesis2R15DK121246-02A1NOVAK, COLLEEN MKENT STATE UNIVERSITY, OH$458,899BMDM
2024Halogenase Inspired Chemical Catalysis and Methods2R15GM139156-02LI, WEIUNIVERSITY OF TOLEDO, OH$458,584CSB
2024Regulation of epithelial junctions stability and turnover by the RhoG exchange factor SGEF1R15GM155874-01GARCIA-MATA, RAFAELUNIVERSITY OF TOLEDO, OH$458,500ZRG1
2024Temperature-sensitive germline structures and temperature thresholds of fertility in Caenorhabditis nematodes1R15GM154234-01PETRELLA, LISA NICOLEMARQUETTE UNIVERSITY, WI$458,050ZRG1
2024Green Synthesis of Building Blocks and APIs by High Hydrostatic Pressure-initiated Synthesis1R15GM157702-01TOROK, BELAUNIVERSITY OF MASSACHUSETTS BOSTON, MA$457,500CSB
2024Discovery of germline genes and regulatory networks in planarians2R15HD082754-04ROUHANA, LABIBUNIVERSITY OF MASSACHUSETTS BOSTON, MA$457,500ZRG1
2024The development of the trade-off between sampling and remembering the visual world1R15HD115244-01BLASER, ERIKKALDY, ZSUZSANNAUNIVERSITY OF MASSACHUSETTS BOSTON, MA$457,294HCMF
2024Aging Effects on Mechanoregulation of Osteocytes using Multiscale Multiphysics1R15AG080524-01A1GANESH, THIAGARAJANUNIVERSITY OF MISSOURI KANSAS CITY, MO$456,085ZRG1
2024Molecular insights into acute and chronic hypoxia tolerance: Investigating mechanisms of short-term plasticity and long-term genetic adaptation1R15GM152940-01LAMICHHANEY, SANGEETKENT STATE UNIVERSITY, OH$456,000ZRG1
2024The hemoglobin beta subunit regulates chromatin and transcription to adapt to metabolic demands1R15NS133909-01A1MCDONOUGH, JENNIFERKENT STATE UNIVERSITY, OH$456,000NOMD
2024Understanding and Designing pH-Responsive Peptides in Confined Nanoscale Environments1R15GM155859-01ROSS, MICHAEL BUNIVERSITY OF MASSACHUSETTS LOWELL, MA$455,940MSFB
2024Molecular and cellular mechanisms underlying Fgf8-dosage mediated defects in jaw size and symmetry1R15DE033850-01FISH, JENNIFER LESLIEUNIVERSITY OF MASSACHUSETTS LOWELL, MA$455,939ZRG1
2024Regulation of SWI/SNF chromatin remodeler composition and function.1R15GM151701-01DUTTA, ARNOBUNIVERSITY OF RHODE ISLAND, RI$455,630ZRG1
2024Molecular probes for targeting facilitative fructose transporters (GLUTs) in biochemical and biomedical applications2R15CA242401-02A1TANASOVA, MARINAMICHIGAN TECHNOLOGICAL UNIVERSITY, MI$455,433CBP
2024Persistent Effects of Dietary Protein Restriction on Protein Motivation and Underlying Physiology1R15DK139555-01SOTO, PAULLOUISIANA STATE UNIV A&M COL BATON ROUGE, LA$455,398BRLE
2024How do early stages of fibrin fiber assembly affect clot structure and lysis2R15HL148842-02HUDSON, NATHANEAST CAROLINA UNIVERSITY, NC$455,082HTBT
2024Determining how redox changes affect optic tectum circuitry development and behavior.1R15NS131998-01A1SULI, ARMINDABRIGHAM YOUNG UNIVERSITY, UT$454,500NOMD
2024Ventral Tegmental Area GABA Neurons: Plasticity & Opiate Receptors at InhibitoryInputs2R15DA049260-02A1EDWARDS, JEFFREY GBRIGHAM YOUNG UNIVERSITY, UT$454,500MCNP
2024Membrane cholesterol homeostasis in human brain cells derived from iPSCs1R15AG085620-01A1ZHANG, QIFLORIDA ATLANTIC UNIVERSITY, FL$454,271CMND
2024Understanding transcriptional silencing & anti-silencing mechanisms in Shigella2R15AI090573-05WING, HELEN JUNIVERSITY OF NEVADA LAS VEGAS, NV$453,709ZRG1
2024Mechanisms required to compartmentalize the stem cell niche during organogenesis.1R15GM154246-01ANLLO, LAUREN M.EAST CAROLINA UNIVERSITY, NC$453,000ZRG1
2024Effect of Sensorineural Hearing Loss on the Neural Coding of Spatial Hearing2R15DC017616-02A1DAY, MITCHELL LEEOHIO UNIVERSITY ATHENS, OH$453,000AUD
2024Transfer of function across equivalence classes: Implications for substance use1R15DA058909-01A1BRUCE, KATHERINE ELYGALIZIO, JOSEPH MARKUNIVERSITY OF NORTH CAROLINA WILMINGTON, NC$451,750BRLE
2024Speech Localization and Enhancement for Next-Generation Hearing Devices1R15DC021563-01GAI, YANSAINT LOUIS UNIVERSITY, MO$451,688ZRG1
2024Deep Learning Methods to Integrate Biological Information for Analysis of Single-cell RNAseq Data2R15HG012087-02WEI, ZHINEW JERSEY INSTITUTE OF TECHNOLOGY, NJ$450,034ASPA
2024FBXL16 as a novel factor in promoting endocrine therapy resistance and metastasis of ER+ breast cancer1R15CA280818-01A1LONG, WEIWENWRIGHT STATE UNIVERSITY, OH$450,000ZRG1
2024Investigating the functional roles of Arl6ip5 in suppressing thrombosis1R15HL172202-01WESTRICK, RANDAL JOAKLAND UNIVERSITY, MI$450,000HTBT
2024High dimensional motor coding and motor dysfunction in Rett syndrome1R15NS135396-01A1SHEW, WOODROW L.UNIVERSITY OF ARKANSAS AT FAYETTEVILLE, AR$450,000SMN
2024Developing a CRISPR-based forward-genetic screening method in embryonic zebrafish2R15HD098969-02A1HILL, JONATHON TBRIGHAM YOUNG UNIVERSITY, UT$449,350ZRG1
2024Catalytic Reductive C-H and C-C Silylation with Silyl Acetals2R15GM116031-03JEON, JUNHAUNIVERSITY OF TEXAS ARLINGTON, TX$449,248CSB
2024Candida albicans phenotypic switching: Transcriptional regulation and virulence attributes1R15AI185747-01HERNDAY, AARON DUNIVERSITY OF CALIFORNIA, MERCED, CA$449,048PTHE
2024Mutlifunctional Nanocomposite Bioadhesive for Diabetic Wound Repair2R15GM135875-02LEE, BRUCE PMICHIGAN TECHNOLOGICAL UNIVERSITY, MI$448,936DBTD
2024Engineering Enzymes for Improved Stability and Retained Function via Rapid Design-Build-Test-Learn Cycles integrating AI/Physics based predictions with Cell-free Protein Synthesis Experimental Testing1R15GM155803-01DELLA CORTE, DENNISBRIGHAM YOUNG UNIVERSITY, UT$448,723MSFA
2024Understanding and improving novel oncolytic viruses for pancreatic cancer1R15CA280729-01A1GRDZELISHVILI, VALERY ZURABOVICHUNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$448,536ZRG1
2024Investigating common luminophore in protein-metal nano-complexes1R15GM154313-01EGUSA, SHUNJIUNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$448,536ZRG1
2024The impact of maternal cyanotoxin ingestion on the development and function of the stress axis in offspring1R15ES036710-01CHUNG, WILSONKENT STATE UNIVERSITY, OH$448,383DBD
2024Maturation Strategies for Engineered Human Cardiac Microtissues1R15HL172207-01ZHANG, GEUNIVERSITY OF AKRON, OH$448,200ZRG1
2024Molecular Mechanism of Folding of Nsp12 and Assembly of the SARS-CoV-2 RNA Polymerase Complex by the Cytosolic Chaperonin CCT1R15GM157661-01WILLARDSON, BARRY MBRIGHAM YOUNG UNIVERSITY, UT$447,548MSFC
2024Convolutional Neural Network for Disease Prediction, Biomarker Discovery, and Validation in Alzheimer's Disease1R15AG083618-01A1CHEN, JINGCHUNUNIVERSITY OF NEVADA LAS VEGAS, NV$447,509ASPA
2024MitoNEET is a Regulator of the Cellular Thiol State in Health and Disease1R15GM154239-01KONKLE, MARYBALL STATE UNIVERSITY, IN$447,337MSFA
2024A Search for Safer Plastics: Synthesis and Reproductive Toxicity Evaluation of Novel Bisphenols1R15ES034520-01A1KUZMANOV, ALEKSANDRATIMMONS, SHANNONLAWRENCE TECHNOLOGICAL UNIVERSITY, MI$446,867EDD
2024Evidence of neurogenesis in an adult mammalian retina initiated by an alpha7 nAChR agonist1R15EY035803-01LINN, CINDY LWESTERN MICHIGAN UNIVERSITY, MI$446,433ZRG1
2024Investigations of drug encapsulation in polymer nanoparticles: Training undergraduate students in multidisciplinary research1R15GM155853-01VAN KEUREN, EDWARDGEORGETOWN UNIVERSITY, DC$446,239INN
2024Chemoenzymatic synthesis of trehalose analogues as tools for investigating mycobacteria2R15AI117670-03SWARTS, BENJAMIN MICHAELWOODRUFF, PETER JCENTRAL MICHIGAN UNIVERSITY, MI$445,611CSB
2024The Role of Mouse Zinc Transporter ZIP12 in Brain Development1R15HD112892-01A1CHOWANADISAI, WINYOOOKLAHOMA STATE UNIVERSITY STILLWATER, OK$445,552DBD
2024Maternal Interleukin-4 and allergic asthma in mouse offspring behavioral deficits2R15MH119500-02SCHWARTZER, JAREDMOUNT HOLYOKE COLLEGE, MA$443,738ZRG1
2024Examining how visual experience modulates the thalamus and visuomotor responses.1R15EY036226-01HORSTICK, ERIC JAMESWEST VIRGINIA UNIVERSITY, WV$443,599NBVP
2024Mechanistic insight into tumor-associated MUC1 glycopeptides binding to macrophage galactose-type lectin2R15CA242351-02CUDIC, MAREFLORIDA ATLANTIC UNIVERSITY, FL$443,151CSB
2024Immunometabolic Regulation of Adipose Tissue by CTRP61R15DK136102-01A1LEI, XIAOKLAHOMA STATE UNIVERSITY STILLWATER, OK$442,844BMDM
2024Synthesis of Natural Products by Oxidative Dearomatization and Discovery of BRAT1 Degraders1R15GM154274-01YUAN, YUUNIVERSITY OF CENTRAL FLORIDA, FL$441,469CSB
2024Phase behavior of proteins in crowded environments1R15GM154243-01XU, AMYLOUISIANA STATE UNIV A&M COL BATON ROUGE, LA$441,108MSFB
2024The Developmental Effects of Environmental Enrichment on the Minor Cannabinoid Drug Reward and Cannabinoid Receptor Levels1R15DA058811-01STAIRS, DUSTIN JEFFREYCREIGHTON UNIVERSITY, NE$440,924BRLE
2024New Methods for Synthesizing Bioactive Peptides2R15GM114789-03CASTLE, STEVEN LBRIGHAM YOUNG UNIVERSITY, UT$440,904CSB
2024Skin Lesion Archive and Annotation for Fusion and Earlier Skin Cancer Detection1R15CA287304-01BECEVIC, MIRNAGRICHNIK, JAMES MSTANLEY, RONALD JSTOECKER, WILLIAM VMISSOURI UNIVERSITY OF SCIENCE & TECHNOLOGY, MO$440,011EITA
2024PROVIDE NEW INSIGHTS IN ALPHA-SYNUCLEIN INDUCED CELL MEMBRANE DISRUPTION USING SCANNING ION CONDUCTANCE MICROSCOPY AND SURFACE PLASMON RESONANCE MICROSCOPY2R15NS120157-02WANG, YIXIANCALIFORNIA STATE UNIVERSITY LOS ANGELES, CA$438,000BBM
2024Functional Analysis of Locus-Specific Pericentric Satellite Expression2R15GM134495-02A1CARONE, DAWN M.SWARTHMORE COLLEGE, PA$437,442ZRG1
2024Metabolic regulation of the stem cell niche1R15AG085260-01A1DEMARCO, RAFAEL SUNIVERSITY OF LOUISVILLE, KY$437,366ZRG1
2024Mechanisms of Antifungal Activity of Dendritic Cell Lysosomal Proteins1R15AI183184-01WOZNIAK, KAREN LYNNOKLAHOMA STATE UNIVERSITY STILLWATER, OK$437,263AIRT
2024Interaction of β-Hairpin Peptides with Membranes1R15GM146166-01A1ALMEIDA, PAULO FUNIVERSITY OF NORTH CAROLINA WILMINGTON, NC$436,429BBM
2024Hyperstable FGF1-FGF2 based therapeutic formulation for wound care1R15GM154267-01THALLAPURANAM, SURESH KUMAR KRISHNASWAMYUNIVERSITY OF ARKANSAS AT FAYETTEVILLE, AR$435,226ZRG1
2024Context and multiple meanings: Homophone learning in early childhood1R15HD115135-01CONWELL, ERINNORTH DAKOTA STATE UNIVERSITY, ND$434,929LCOM
2024Molecular Consequences of Myotonic Dystrophy Type 2-causing CCTG DNA Repeats1R15GM155842-01KIM, JANE CCALIFORNIA STATE UNIVERSITY SAN MARCOS, CA$434,750ZRG1
2024TLT-1 intracellular function1R15HL175494-01WASHINGTON, A. VALANCEOAKLAND UNIVERSITY, MI$434,658HTBT
2024Enantioselective Catalytic Chlorosilane Reactions2R15GM139087-02TAKENAKA, NORITOFLORIDA INSTITUTE OF TECHNOLOGY, FL$434,607CSB
2024Customizable 3D Matrix to Investigate Glycan Function1R15GM157707-01BRICHACEK, MATTHEW PAULUNIVERSITY OF MAINE ORONO, ME$434,385ZRG1
2024Genetic predisposition and misdiagnosis of cancer in All of Us participants1R15CA293800-01BAILEY, MATTHEW HBRIGHAM YOUNG UNIVERSITY, UT$434,379CHD
2024Light-Controlled Supramolecular Platinum Complexes for Biomedical Applications1R15GM152919-01ZHENG, YAORONGKENT STATE UNIVERSITY, OH$434,148CSB
2024Early GABAergic signaling influences axon morphology and cortical cell polarity2R15NS124008-02HINES, ROCHELLE MARIEUNIVERSITY OF NEVADA LAS VEGAS, NV$433,661NDPR
2024Attention Regulation Strategies Used by Deaf and Hearing Parents of Autistic Children1R15DC021828-01A1SHIELD, AARON M.MIAMI UNIVERSITY OXFORD, OH$433,438CPDD
2024Regulation of the Vibrio cholerae MSHA Pilus Drives Host Colonization and Pathogenesis1R15AI185921-01FLOYD, KYLE AILLINOIS STATE UNIVERSITY, IL$432,741ZRG1
2024Spatiotemporal control of RGS signaling1R15GM155864-01KELLEY, JOSHUA BRIANUNIVERSITY OF MAINE ORONO, ME$432,422ZRG1
2024Neural Circuitry Mechanisms Underlying Maladaptive Reward Memories in Drosophila1R15AA031562-01SCAPLEN, KRISTIN MARIEBRYANT UNIVERSITY, RI$431,918NMB
2024Aim32, a multi-faceted redox protein, in mitochondrial biogenesis2R15GM134451-02DABIR, DEEPA VINAYLOYOLA MARYMOUNT UNIVERSITY, CA$431,700ZRG1
2024Rational Design of Nickel Catalysts for Directing Group-Assisted Alkyne Hydrofunctionalization1R15GM155845-01YAN, CHANGHUIZHAO, PINJINGNORTH DAKOTA STATE UNIVERSITY, ND$431,400CSB
2024The Role of Phosphoinositides in Influenza Virus Assembly1R15GM155811-01HESS, SAMUEL TUNIVERSITY OF MAINE ORONO, ME$430,613MSFC
2024Control of cell polarity and migration by non-centrosomal microtubules2R15GM139063-03MYERS, KENNETH ALBERTSAINT JOSEPH'S UNIVERSITY, PA$429,352ZRG1
2024Integrative analysis of electrical and mechanical dyssynchrony to improve cardiac resynchronization therapy1R15HL173852-01SHA, QIUYINGMICHIGAN TECHNOLOGICAL UNIVERSITY, MI$429,153CDMA
2024Reverse engineering cancer cachexia: muscle ribosome biogenesis in the etiology of cachexia1R15AR083675-01FIGUEIREDO, VANDRE CASAGRANDEOAKLAND UNIVERSITY, MI$429,048ZRG1
2024Functional diversity of large ribosomal protein 27 and small ribosomal protein 19 paralogs1R15GM157708-01REID, KE ZHANGWAKE FOREST UNIVERSITY, NC$428,973ZRG1
2024Pharmacologically tuning membrane permeability to drug-sized organic cations through activation of KCa3.1 channels1R15GM155885-01SAMWAYS, DAMIENCLARKSON UNIVERSITY, NY$428,924BBM
2024Causes and consequences of virulence factor attenuation in Mycoplasma pneumoniae biofilms1R15AI183099-01BALISH, MITCHELL FMIAMI UNIVERSITY OXFORD, OH$427,996BHI
2024Grape Seed Extract Modulation of Peripheral and Central Nervous System Neuron-Glia Interactions1R15AT012501-01A1DURHAM, PAUL LMISSOURI STATE UNIVERSITY, MO$427,500ZAT1
2024Multi-modality Image Fusion to Improve Coronary Revascularization in Patients with Stable Coronary Artery Disease1R15HL172198-01ZHOU, WEIHUAMICHIGAN TECHNOLOGICAL UNIVERSITY, MI$427,307ITD
2024Impact of endogenous retroviruses in the domestic dog1R15GM154237-01HALO, JULIA VERABOWLING GREEN STATE UNIVERSITY, OH$426,000ZRG1
2024Role of Vesicular Trafficking Proteins in Regulating Centrosomes1R15GM152965-01A1IYER, JYOTIUNIVERSITY OF TULSA, OK$426,000ZRG1
2024Regulation of HSP70 function during heat stress tolerance1R15GM157698-01QIU, YONGJIANUNIVERSITY OF MISSISSIPPI, MS$425,803ZRG1
2024The Role of Mechanical Stress in Mitigating Side Effects of Chemotherapy1R15CA293993-01ZAVALA, ANAMARIA GABRIELLABOISE STATE UNIVERSITY, ID$424,500ZRG1
2024Integrating data from a wideband acoustic immittance database to develop machine-learning models that characterize pathology in auditory measurements2R15DC014129-03A1VOSS, SUSAN ESMITH COLLEGE, MA$423,986AUD
2024Use of Vibrational Reporters to Measure Dynamics and Distances in RNA and Proteins2R15GM093330-04BREWER, SCOTT HFENLON, EDWARD EMMETTFRANKLIN AND MARSHALL COLLEGE, PA$423,133MSFB
2024The direct transcriptional regulation of cell cycle genes by cell identity factors during myeloid differentiation1R15HL172092-01A1MANU, MANUUNIVERSITY OF NORTH DAKOTA, ND$423,000HTBT
2024Establishing Drosophila melanogaster as a model for developmental neurotoxicity assessment of air pollutants using diesel exhaust1R15ES036345-01MILLER-SCHULZE, JUSTIN P.MULLIGAN, KIMBERLY ANNECALIFORNIA STATE UNIVERSITY SACRAMENTO, CA$421,705NAL
2024Identifying biomarkers for the early detection of Alzheimer's disease using phage display2R15AG066122-02GUTTMANN, RODNEY PUNIVERSITY OF WEST FLORIDA, FL$421,500CDIN
2024Opioid Use Disorder Pharmaceutical Treatments: Investigating a Model and Measure of Intervention Stigma toward Medication (OPTIMISM)1R15DA059765-01A1WINOGRAD, RACHELUNIVERSITY OF MISSOURI-ST. LOUIS, MO$421,499ZRG1
2024Characterization of SAM gene mutation impacts on cellular processes and genome instability2R15GM132818-02STROME, ERIN DNORTHERN KENTUCKY UNIVERSITY, KY$420,000ZRG1
2024Molecular control of translesion synthesis fidelity beyond the lesion1R15GM155805-01TRAKSELIS, MICHAEL ABAYLOR UNIVERSITY, TX$420,000MSFC
2024Design and Development of an Evidence-based Cognitive Aid for Out-of-Hospital Treatment of Pediatric Patients1R15LM014556-01ZHANG, ZHANPACE UNIVERSITY NEW YORK, NY$419,294CIDH
2024Systematic Functional Genomics Analysis of the Oral Pathogen Streptococcus Mutans1R15DE034550-01ALAM, MOHAMMAD ABRARARKANSAS STATE UNIVERSITY, AR$419,161ZRG1
2024Miniature Selective Plane Illumination Fluorescence Microscope for High-resolution Volumetric Imaging in Freely Behaving Mice1R15NS135507-01A1LIANG, BOUNIVERSITY OF NORTH DAKOTA, ND$419,038ZRG1
2024Investigation of blood fitness genes in the tsetse fly symbiont Sodalis glossinidius1R15AI178416-01A1RUNYEN-JANECKY, LAURA JANEUNIVERSITY OF RICHMOND, VA$416,165TVZ
2024Development and Validation of Remaining Measures to Assess the Bystander Intervention for Problematic Alcohol Use Model (BIPAUM)1R15AA031833-01MENNICKE, ANNELISEMONTANARO, ERIKA ANNUNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$415,769ASPB
2024Investigation of the serine protease Masp1 as a novel regulator of Bmp signaling during early embryonic development.1R15HD112869-01A1RAY, HEATHER JOYIDAHO STATE UNIVERSITY, ID$415,376ZRG1
2024Engineering and Characterization of pH dependent Antibodies1R15GM155846-01HORN, JAMES R.NORTHERN ILLINOIS UNIVERSITY, IL$415,329MSFB
2024Genetic Identification of Bacterial RNA Chaperone Proteins and their Mechanisms of Action2R15GM135878-02BERRY, KATHERINE EMOUNT HOLYOKE COLLEGE, MA$414,047ZRG1
2024Investigating the role of lipid metabolism in the biogenesis of lysosome-related organelles1R15GM154211-01HERMANN, GREG JLEWIS AND CLARK COLLEGE, OR$414,000ZRG1
2024Developing new biophysical models of choroid fissure closure in zebrafish and foveal pit formation across species1R15EY035473-01A1ENGSTROM, TYLERJAMES, ANDREA EUNIVERSITY OF NORTHERN COLORADO, CO$413,920MABS
2024Deciphering the Thalamic Reticular Functions of Phospholamban1R15MH136640-01PITYCHOUTIS, POTHITOSUNIVERSITY OF DAYTON, OH$413,681SMN
2024Cell Death Programs as Fundamental Drivers of Inflammation and Multi-Organ Injury1R15AI185729-01MANDAL, PRATYUSHAHERBERT H. LEHMAN COLLEGE, NY$412,746III
2024Influence of early life physical inactivity during a key period of postnatal development on adult muscle quality – from matrix to mortality1R15AR084182-01REIDY, PAUL TIMOTHYMIAMI UNIVERSITY OXFORD, OH$410,071ZRG1
2024Photocatalyzed and Enantioselective Umpolung C-C Bond Forming Reactions of Carbonyls2R15GM137238-02A1CANNON, JEFFREYOCCIDENTAL COLLEGE, CA$409,456CSB
2024Elucidating the neural oscillations of the sensory-discriminative and affective-motivational dimensions of pain.1R15NS137286-01A1HARRIS BOZER, AMBERTARLETON STATE UNIVERSITY, TX$408,000NPI
2024Leveraging symbiosis and desert biogeography for discovery of host-selected natural products1R15GM147873-01A1VAN ARNAM, ETHAN BUGGIESCRIPPS COLLEGE, CA$407,608CSB
2024Efficient red-to-NIR photo-uncaging and applications in therapy1R15EB034477-01A1ZHANG, YUANWEINEW JERSEY INSTITUTE OF TECHNOLOGY, NJ$406,832ZRG1
2024Investigating the mechanism of action of antibacterial synthetic unsaturated fatty acids in methicillin-resistant Staphylococcus aureus1R15GM143681-01A1SANABRIA, DAVIDINTER AMERICAN UNIVERSITY/PUERTO RICO, PR$405,015BBM
2024The Identification of Clinically Relevant Metabolic Inhibitors to Treat Gammaherpesvirus Infections1R15AI185858-01DELGADO, TRACIESEATTLE PACIFIC UNIVERSITY, WA$404,724AIRT
2024Investigating Cross-regulation of Staphylococcal Metabolism In The Agr Quorum Sensing System1R15AI180723-01A1JAMES, KIMBERLY LASHUNFLORIDA GULF COAST UNIVERSITY, FL$404,055BV
2024Understanding Catalytic Mechanisms of Human Non-Heme Fe(II) and 2-Oxoglutarate-Dependent Histone Demethylases2R15GM139118-02CHRISTOV, CHRISTO ZHIVKOVMICHIGAN TECHNOLOGICAL UNIVERSITY, MI$403,453MSFA
2024Understanding Mechanisms of Antibiotic Inhibition of Ribosomal Subunit Joining1R15GM151696-01A1GIRODAT, DYLAN JOSEPHUNIVERSITY OF ARKANSAS AT FAYETTEVILLE, AR$403,423MSFC
2024Structure and Function of DcrB, an Enterobacterial Copper Resistance Protein1R15GM152892-01MAY, JOHNUNIVERSITY OF WISCONSIN LA CROSSE, WI$401,680MSFA
2024OLD family nuclease function across diverse anti-phage defense systems1R15GM157664-01THURTLE-SCHMIDT, BRYAN HDAVIDSON COLLEGE, NC$400,790ZRG1
2024Developmental and Serotonin 5-HT2A Receptor Effects on Fentanyl Reinforcer Value1R15DA059721-01A1GARCIA, ERIK JOSEPHUNIVERSITY OF NEBRASKA OMAHA, NE$400,294PMDA
2024Macrophage Second-line Responses to Group A Streptoccocus Infection1R15AI176429-01A1OKUMURA, CHERYL YMOCCIDENTAL COLLEGE, CA$397,931BHI

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