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NIH funding notice PAR-24-152

Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)

Closed on January 7, 2025.

Posted
May 8, 2024
Close date
January 7, 2025
Activity codes
R15
Institutes taking part
NIGMS, NEI, NHLBI, NHGRI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIDA, NIEHS, NIMH, NINDS, NINR, NLM, NCCIH, NCI

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PAR-21-155 Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)
  2. 2 steps back: PAR-18-714 Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)

Replaced by PAR-25-134.

Who won it before

1,303 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $552,185,821 in first-year total cost, median $433,661.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 MDCN-R (86)]95
  2. Macromolecular Structure and Function A Study Section[MSFA]64
  3. Synthetic and Biological Chemistry A Study Section[SBCA]50
  4. Macromolecular Structure and Function B Study Section[MSFB]48
  5. Special Emphasis Panel[ZRG1 BST-F (80)]46

Most frequent institutions

  1. MICHIGAN TECHNOLOGICAL UNIVERSITY33
  2. BRIGHAM YOUNG UNIVERSITY32
  3. UNIVERSITY OF TOLEDO23
  4. UNIVERSITY OF NORTH CAROLINA CHARLOTTE22
  5. MIAMI UNIVERSITY OXFORD19
Competing awards under PAR-24-152 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025Biomechanical and biomolecular characterization of large extracellular vesicles1R15CA294070-01A1DAHL, JOANNA BECHTELUNIVERSITY OF MASSACHUSETTS BOSTON, MA$617,325DBTD
2025Linker histone H1 and variant histone H2A.Z interactions in gene silencing and chromosome segregation1R15GM160956-01HOLMES, SCOTT GWESLEYAN UNIVERSITY, CT$598,500ZRG1
2025How Does a Synaptonemal Complex Protein Promote Crossover Recombination and Synapsis?2R15GM116109-04MACQUEEN, AMY JOYWESLEYAN UNIVERSITY, CT$598,500ZRG1
2025Explainable Analogical Learning for Oncology Diagnosis and Prediction based on Deep Pathophysiology1R15CA297754-01A1BICHINDARITZ, ISABELLECOLLEGE AT OSWEGO, NY$591,468CDMA
2025Cardiac Sensory and Sympathetic Nerve Dysregulation in Hypertrophic Cardiomyopathy1R15HL177713-01A1LARSON, ROBERT ARNOLDMICHIGAN TECHNOLOGICAL UNIVERSITY, MI$589,998ZRG1
2025Fractionation of RBCs via label-free magnetophoresis using novel additive-manufactured devices1R15HL181720-01GOMEZ PASTORA, JENIFERTEXAS TECH UNIVERSITY, TX$587,878ZRG1
2025Pre-vascularization of an Integrated 3D Human Osteo-Mucosal Model1R15DE035277-01TAYEBI, LOBATOLD DOMINION UNIVERSITY, VA$583,826ZRG1
2025Computer-Aided Drug Design Targeting Protein Phosphorylation2R15CA224033-03WONG, CHUNG F.UNIVERSITY OF MISSOURI-ST. LOUIS, MO$581,564MSFA
2025The function of chromatin remodeling in the patterning of the salamander limb2R15HD092180-03A1MCCUSKER, CATHERINE DUNIVERSITY OF MASSACHUSETTS BOSTON, MA$580,781ZRG1
2025Elucidating the sequence code for amyloid peptide self-assembly through all-atom simulations, machine learning, and experiments2R15GM148982-02DIAS, CRISTIANO LUISNEW JERSEY INSTITUTE OF TECHNOLOGY, NJ$580,150MSFB
2025Mechanistic studies into regulation of the copper chaperone CCS by phosphorylation1R15GM160944-01GE, EVAUNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$577,500MSFA
2025A Novel Microneedle-Based, Sandwiched Structure for Effective Intraperitoneal Adhesion (IA) Prevention: Material Fabrication and Molecular Level Mechanism Exploration1R15EB037360-01WEI, MEIROWAN UNIVERSITY, NJ$577,488ZRG1
2025Ratiometric Near-Infrared Probes Utilizing BODIPY Dyes for Viscosity and Protein Aggregation Sensing in Live Cells1R15CA305552-01LIU, HAIYINGMICHIGAN TECHNOLOGICAL UNIVERSITY, MI$576,493ZRG1
2025Evolution of pleiotropic consequences via mucoid phage resistance in Escherichia coli populations1R15GM159330-01BURMEISTER, ALITAUNIVERSITY OF WISCONSIN MILWAUKEE, WI$572,553ZRG1
2025A Forward Genetic Screen to Identify Genes Involved in Amphetamine Action1R15DA062968-01CARVELLI, LUCIAFLORIDA ATLANTIC UNIVERSITY, FL$571,675MCNP
2025Episodic Future Thinking in Early Childhood: Neural and Behavioral Indices of Memory and Planning1R15HD118566-01BLANKENSHIP, TASHAUNAUNIVERSITY OF MASSACHUSETTS BOSTON, MA$571,311HCMF
2025Zonal-Specific Mineralized Scaffolds for Osteochondral Regeneration1R15AR086482-01YU, LEUNIVERSITY OF MISSOURI KANSAS CITY, MO$570,174ZRG1
2025The Role of Local Sleep Disturbance in Obesity Risk: A Sleep Neuroimaging Study1R15HL170174-01A1DURACCIO, KARA MCRAEKAY, DANIEL BBRIGHAM YOUNG UNIVERSITY, UT$568,125BMDM
2025Nr4a1 and the expansion of functional beta-cell mass1R15DK144832-01TESSEM, JEFFERY SIVERTBRIGHAM YOUNG UNIVERSITY, UT$568,075BMDM
2025Novel Glycogen Synthase Kinase-3 (GSK-3) Inhibitors as Therapeutic Agents2R15GM110602-03GOETZ, DOUGLAS JOHIO UNIVERSITY ATHENS, OH$566,250CSB
2025Synthetic and Spectroscopic Investigations of Sulfur Oxidation Reactions by Nonheme Iron Enzymes2R15GM126522-02FIEDLER, ADAM TMARQUETTE UNIVERSITY, WI$564,204MSFA
2025Regulators of The Unfolded Protein Response Signaling1R15GM159328-01A1DEY, MADHUSUDANUNIVERSITY OF WISCONSIN MILWAUKEE, WI$563,880ZRG1
2025Probing the Role of Insulin-Like Growth Factor-Binding Protein 3 and Humanin in Regulating Hyaluronan Function2R15GM131222-03GUY EVANS, HEDEEL I.EASTERN MICHIGAN UNIVERSITY, MI$562,500CSF1
2025Studying lysine aminoacylation of human metabolic enzymes1R15GM159279-01FAN, CHENGUANGUNIVERSITY OF ARKANSAS AT FAYETTEVILLE, AR$562,500MSFB
2025The Characterization of RNA Binding Motif Protein 48 (RBM48) in U12 Intron Splicing, Cellular Differentiation, and Development1R15GM159272-01LAL, SHAILESHOAKLAND UNIVERSITY, MI$562,500CSF1
2025CTCF-mediated regulation of partial epithelial-mesenchymal transition states1R15GM159274-01TAUBE, JOSEPH H.BAYLOR UNIVERSITY, TX$562,499ZRG1
2025Bile acid-mediated OEA-PPARa signaling in food intake regulation1R15DK138480-01A1HIGUCHI, SEIST. JOHN'S UNIVERSITY, NY$562,499BMDM
2025The role of pseudouridine synthases in autophagy1R15GM159346-01DELORME-AXFORD, ELIZABETHOAKLAND UNIVERSITY, MI$562,320CSRS
2025Defining the roles of small KH-domain RNA binding proteins in mycobacteria1R15GM159259-01SHELL, SCARLET SARAWORCESTER POLYTECHNIC INSTITUTE, MA$562,123ZRG1
2025Nucleic Acid Nanoparticle-based Monoclonal Antibody Mimics2R15EB031388-02A1KHISAMUTDINOV, EMILBALL STATE UNIVERSITY, IN$560,460ZRG1
2025A Multi-skills Approach for Low Literate Adult Learners2R15HD067755-04A1BINDER, KATHY SUSANMOUNT HOLYOKE COLLEGE, MA$560,134LCOM
2025Decoding the role of naturally occurring variation in genetic and neural regulation of feeding and energy homeostasis.1R15DK144843-01DUBOUE, ERIK ROLANDOFLORIDA ATLANTIC UNIVERSITY, FL$559,918NIC
2025Olfactory Combinatorial Coding in C. elegans1R15DC022738-01BAMBER, BRUCE AUNIVERSITY OF TOLEDO, OH$559,782NIC
2025Investigation of overlap between mitotic and ferroptotic pathways using novel hybrid small molecule inhibitors.1R15GM160971-01TAYLOR, WILLIAM R.UNIVERSITY OF TOLEDO, OH$559,543ZRG1
2025Coagulations 'Drake Passage': The Bumpy Transition Between Fibrinogen and Fibrin1R15HL179651-01OFFENBACHER, ADAMEAST CAROLINA UNIVERSITY, NC$558,697HTBT
2025Mechanism of a hypothiocyanous acid reductase1R15GM159047-01STULL, FREDERICKWESTERN MICHIGAN UNIVERSITY, MI$558,493MSFA
2025Precision-guided gastrointestinal therapy: a cheek-tethered capsule approach for targeted IBD disease treatment1R15DK144844-01TERRY, BENJAMINBRIGHAM YOUNG UNIVERSITY, UT$556,876ZRG1
2025Transition metal photosensitizers with metal-metal bonds1R15GM160969-01KARUNANANDA, MALKANTHI KUMARIHAMYSAINT LOUIS UNIVERSITY, MO$556,651CSB
2025DNA Binding Dynamics and Oligomerization of Sensors of the PYHIN family in Pattern Recognition1R15AI192356-01DE ALBA BASTARRECHEA, EVAUNIVERSITY OF CALIFORNIA, MERCED, CA$556,427MSFB
2025Understanding the Thermodynamics and Structure of RNA Secondary Structure Motifs2R15GM085699-05ZNOSKO, BRENTSAINT LOUIS UNIVERSITY, MO$555,013MSFB
2025The endocytic requirements for mechanosensitive Notch activation in vivo1R15GM160954-01LANGRIDGE, PAULAUGUSTA UNIVERSITY, GA$555,000ZRG1
2025Project HOPE - Exploring the Role of Harm Reduction Vending Machines in Reducing the Risk of HIV Infection and Transmission1R15DA064537-01HERRERA, ASHLEIGH NICOLE SCINTACALIFORNIA STATE UNIVERSITY BAKERSFIELD AUXILIARY FOR SPONSORED PROGRAMS ADMINISTRATION, CA$554,922HIBI
2025Intestinal Microbial Communities and Metabolites Changes Associated with Long-term Stress Induced Inflammatory Bowel Disease1R15DK140841-01A1SINGH, PALLAVINORTHERN ILLINOIS UNIVERSITY, IL$554,874DHMI
2025J-Protein Regulation of Yeast Prion Propagation2R15GM110606-04HINES, JUSTIN KEITHLAFAYETTE COLLEGE, PA$553,785ZRG1
2025The role of cannabinoid 1 receptor in age-associated diseases1R15DK144838-01KIM, YOOOKLAHOMA STATE UNIVERSITY STILLWATER, OK$551,696ZRG1
2025Development of Gold Nanocarriers for the Treatment ofRheumatoid Arthritis1R15AR085909-01VASQUEZ, YOLANDAWEAVER, JIMMIE DEANOKLAHOMA STATE UNIVERSITY STILLWATER, OK$551,178INN
2025The MYC-SWI/SNF connection in cancers defined by SMARCA4 mutations1R15CA304777-01WEISSMILLER, APRIL M.MIDDLE TENNESSEE STATE UNIVERSITY, TN$549,836ZRG1
2025Distinguishing features of C. albicans pseudouridylation and their roles in pathogenesis2R15AI130950-03A1BERNSTEIN, DOUGLAS A.BALL STATE UNIVERSITY, IN$549,460PTHE
2025Enantioselective desymmetrizing hydroamination to synthesize complex all-carbon quaternary stereocenter containing saturated heterocyclic structures1R15GM160943-01MALACHOWSKI, WILLIAM PBRYN MAWR COLLEGE, PA$548,701CSB
2025Utilization of a novel dissimilarity approach to identify a novel mechanism of Merkel cell polyomavirus small tumor antigen nuclear import responsible for the development of Merkel cell carcinoma1R15CA305115-01DYE, KRISTINE NICOLESTETSON UNIVERSITY, FL$547,875ZRG1
2025Foot biomechanics and metatarsal structure in runners with minimal and cushioned shoes1R15AR085912-01TROY, KAREN LWORCESTER POLYTECHNIC INSTITUTE, MA$546,159ZRG1
2025Genetics of Thrombopoiesis2R15DK117384-02JAGADEESWARAN, PUDURUNIVERSITY OF NORTH TEXAS, TX$545,282HTBT
2025A C. Elegans Model of Fanconi Anemia Neurological Syndrome1R15NS142899-01HOWLETT, NIALL GEORGEUNIVERSITY OF RHODE ISLAND, RI$544,854MNG
2025Defining novel roles of the DNA repair factor REV7 in p53 signaling and regulation1R15CA305114-01TOMIDA, JUNYAUNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$544,712ZRG1
2025Sigma-regulator recognition and activation of regulated intramembrane proteolysis by a site-1 protease during iron import cell surface signaling in Gram-negative bacteria.1R15GM160942-01COLBERT, CHRISTOPHER LNORTH DAKOTA STATE UNIVERSITY, ND$543,750BBM
2025Fluorescent Probes that Span the Spectrum for Multi-Color Imaging of Peroxynitrite in Living Cells1R15GM159260-01DOMAILLE, DYLAN WCOLORADO SCHOOL OF MINES, CO$540,053CSB
2025The role of homeobox transcription factor Nkx2.1 in nervous system development1R15NS141048-01A1HUDSON, MARTIN LYNKENNESAW STATE UNIVERSITY, GA$539,999NCF
2025A single biosensors for the simultaneous molecular detection of HIV and Hepatitis B and C viruses at resource-limited settings1R15AI189259-01A1CHUMBIMUNI-TORRES, KARINUNIVERSITY OF CENTRAL FLORIDA, FL$537,619HVCD
2025Functionalized Receptors for Efficient Epitope Recognition1R15GM160963-01URBACH, ADAM ROBERTTRINITY UNIVERSITY, TX$535,867CBP
2025Assessing the Strength of Weak Ties2R15GM134502-02CHAKRAVARTY, SUVOBRATASOUTH DAKOTA STATE UNIVERSITY, SD$533,726MSFA
2025Function and evolution of strains in the gut microbiota1R15GM160989-01LOPEZ, CHRISTOPHERREAMS, ANDREW B.CALIFORNIA STATE UNIVERSITY SACRAMENTO, CA$532,500ZRG1
2025Mechanisms of Telomere Maintenance and Protection1R15GM160955-01STEWART, JASON AARONWESTERN KENTUCKY UNIVERSITY, KY$531,584ZRG1
2025Discovering targets for neuroblastoma differentiation therapy from the human druggable genome1R15CA305329-01DU, LIQINTEXAS STATE UNIVERSITY, TX$531,550ZRG1
2025Developing Next Generation Eutectic Solvents for Biomedical Applications1R15GM159257-01HALIM, MOHAMMADKENNESAW STATE UNIVERSITY, GA$529,359MSFB
2025Rational design of an adhesin-based pneumococcal vaccine targeting colonization2R15AI142537-02THORNTON, JUSTIN AMISSISSIPPI STATE UNIVERSITY, MS$528,735ZRG1
2025Approaches to heterocyclic rich anti-microbial natural products1R15GM159253-01LOVELY, CARLMISSISSIPPI STATE UNIVERSITY, MS$528,595CSB
2025New Mechanisms of Mitochondrial Toxicity: Focus on Antibacterial Agent Cetylpyridinium Chloride Effects on Immune and Barrier Cells1R15ES037871-01GOSSE, JULIE ANNUNIVERSITY OF MAINE ORONO, ME$526,441EDD
2025Integrating Generative AI with Biomechanics Modeling to Advance Ventricular Disease Diagnosis and Personalized Treatment1R15HL181637-01SHI, LEIKENNESAW STATE UNIVERSITY, GA$522,695ZRG1
2025Differentially expressed genes in male and female DRG during pain and pain-relief; isoform specific cellular expression of RNAs1R15NS140947-01A1POLLOCK, JOHN ARCHIEDUQUESNE UNIVERSITY, PA$517,494NPI
2025The growth of the germline ring canals during Drosophila melanogaster oogenesis2R15HD084243-03A1LEWELLYN, LINDSAY KYLEBUTLER UNIVERSITY, IN$516,934CMIR
2025Investigation of the role of the G protein-coupled receptor FSHR-1 in multi-tissue control of neuromuscular signaling in normal and oxidative stress conditions2R15NS112918-02KOWALSKI, JENNIFERBUTLER UNIVERSITY, IN$516,307NOMD
2025Investigating the role of pH in presynaptic homeostatic potentiation at the vertebrate neuromuscular junction1R15NS139201-01A1LINDGREN, CLARK AGRINNELL COLLEGE, IA$515,078NC
2025Development of a novel exosome-based nano-scavenger for targeted Amyloid-beta removal1R15AG092927-01LU, BIAOSANTA CLARA UNIVERSITY, CA$513,740INN
2025Examining Glycine Receptor's Intracellular Domain by Crosslinking-Mass Spectrometry1R15GM159232-01CASCIO, MICHAELDUQUESNE UNIVERSITY, PA$512,397BBM
2025Activity-based protein profiling of the vaginal microbiome1R15AI194161-01WHIDBEY, CHRISTOPHERSEATTLE UNIVERSITY, WA$511,763IMII
2025Discovery and Characterization of Novel Halogenases from the Human Microbiome and from Archaea2R15GM144877-02BELLIZZI, JOHN J.UNIVERSITY OF TOLEDO, OH$510,554CSB
2025Defining the Biochemical Function and Therapeutic Utility of Unique PARP14 and PARP15 ADP-Ribosylation Sites2R15GM139150-02CARTER-O'CONNELL, IAN O'BRIENSANTA CLARA UNIVERSITY, CA$507,796MSFA
2025Nuclear-Mitochondrial Mismatch in Mitochondrial Function and Disease1R15GM159332-01GIBSON, JOSHUA DANIELGEORGIA SOUTHERN UNIVERSITY, GA$507,544CSRS
2025RNA homodimerization strand displacement pathways to extended duplexes: Atomistic details for a mechanistic paradigm to identify unique antiviral targets for current and emerging viral pandemics1R15AI191143-01A1EVANSECK, JEFFREY DDUQUESNE UNIVERSITY, PA$507,121HVCD
2025Molecular and cellular mechanisms of spinocerebellar ataxia type 52R15NS116511-02AVERY, ADAMOAKLAND UNIVERSITY, MI$505,394NC
2025Examining Estrogenic Regulation of Orexin Neurons to Reveal Subpopulations1R15DK140842-01A1STINCIC, TODD LYNNAPPALACHIAN STATE UNIVERSITY, NC$504,705BNRS
2025Developing Novel Protein-based GABA Sensor Modules Using PLP-dependent GabR Regulators1R15GM160979-01LIU, DALILOYOLA UNIVERSITY OF CHICAGO, IL$503,535MSFB
2025High-throughput characterization and engineering of brighter luciferases2R15GM135860-02LECONTE, AARON MORGANSCRIPPS COLLEGE, CA$503,298CSB
2025Advancing Insight into Maternal Social Support (AIMSS): Group Prenatal Care and Postpartum Mood2R15MH126403-02NORCROSS, PAMELAPREVATT, BETTY-SHANNONMEREDITH COLLEGE, NC$498,747CMGC
2025Tissue Engineering Plant-based Vascular Grafts II2R15EB033168-02MERNA, NICHOLAS J.HOFSTRA UNIVERSITY, NY$492,270AVI
2025Social experience dependent cellular plasticity of brain circuits1R15MH141535-01ISSA, FADI AEAST CAROLINA UNIVERSITY, NC$489,192NMB
2025R15: Enhancement of Genome Editing in Hematopoietic Stem Cells by Nucleic Acids Nanoparticles Delivery of CRISPR/CAS System1R15HL177745-01 · under PAR-21-155FU, JINGLINRUTGERS THE STATE UNIV OF NJ CAMDEN, NJ$486,291ZRG1
2025Aptamers as Novel Inhibitors of the Neurotoxin Beta-methylamino-L-alanine (BMAA)1R15ES037888-01PAWLUS, MATTHEW RYANBLACK HILLS STATE UNIVERSITY, SD$484,122NAL
2025Developing Strategies to Decrease Facial Masking in Parkinson's Disease1R15NS141094-01A1FICHTENHOLTZ, HARLAN M.GUNNERY, SARAHNEW ENGLAND COLLEGE, NH$483,620MESH
2025Activation of type I interferon production in human immune cells by cell-to-cell transmission of HIV-11R15AI192135-01SHI, BINSHANALBANY COLLEGE OF PHARMACY, NY$479,925HIVD
2025Unraveling the Aggregation of TDP43 Fragments Associated with ALS and FTD: Insights into Protein Quality Control Mechanisms and Cellular Vulnerability2R15NS095317-03BROWER, CHRISTOPHER SCOTTTEXAS WOMAN'S UNIVERSITY, TX$476,973CMND
2025Genome-wide chromatin structure and function in Kaposi Sarcoma tissue1R15CA306651-01MIRANDA, JJBARNARD COLLEGE, NY$476,754HCAC
2025Synthesis and Exploration of Highly Fluorescent Thiazolothiazole Molecular Sensors for Probing Membrane Potential Dynamics2R15GM140392-02 · under PAR-21-155WALTER, MICHAEL G.UNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$476,534CBP
2025Cortical actions of opioids on reward-guided decision making1R15DA062121-01A1LAUBACH, MARKAMERICAN UNIVERSITY, DC$476,496NMB
2025Development of novel, daptomycin-inspired antimicrobial peptides using non-canonical amino acids1R15AI188560-01 · under PAR-21-155CAPUTO, GREGORY ALEXANDERROWAN UNIVERSITY, NJ$474,363DMPA
2025IL-17 receptor signaling in megakaryocytes and the implications for oral mucosal immune responses during oropharyngeal candidiasis1R15DE034954-01CONTI, HEATHER RAQUELUNIVERSITY OF TOLEDO, OH$473,632ZRG1
2025Decoupling reproductive and somatic aging using novel C. elegans technology1R15AG089221-01A1SOHRABI, SALMANUNIVERSITY OF TEXAS ARLINGTON, TX$472,793ZRG1
2025Regulation and localization of flp pili: an under-investigated system (Year 4)2R15GM139127-02A1CURTIS, PATRICK DAVIDUNIVERSITY OF MISSISSIPPI, MS$471,486ZRG1
2025Internal water dynamics in hydration shells of amyloid-beta species1R15GM157635-01A1VUGMEYSTER, LILIYAUNIVERSITY OF COLORADO DENVER, CO$466,972BBM
2025Creating an Interactive Computer Model of Left Atrium Electrophysiology to Study the Underlying Mechanisms Leading to Atrial Fibrillation1R15HL179671-01WYATT, BRYANTTARLETON STATE UNIVERSITY, TX$464,502ZRG1
2025Coordinating cellular events during spore development2R15GM086805-05A1 · under PAR-21-155HUANG, LINDA S.UNIVERSITY OF MASSACHUSETTS BOSTON, MA$464,083ZRG1
2025Illuminating the subcellular localization and regulation of D-2-hydroxyglutarate using a novel genetically encoded fluorescent biosensor1R15CA297694-01A1JENNINGS, MATTHEW JAMESPRATT, EVAN PATRICK SAUVIENORTHERN MICHIGAN UNIVERSITY, MI$462,153ZRG1
2025cAMP signaling and three activity states of hippocampal neurons2R15MH125305-02 · under PAR-21-155CHEN, XUANMAOUNIVERSITY OF NEW HAMPSHIRE, NH$460,500NC
2025Synthetic Biology Approaches to Engineer Lactococcus lactis for Targeted Delivery of Therapeutic Lasso Peptides1R15GM152962-01A1HAN, YONGOHIO UNIVERSITY ATHENS, OH$460,166DBTD
2025Investigating NEK10 as a myosin light chain kinase1R15GM157662-01 · under PAR-21-155CRAWLEY, WILLIAM SCOTTUNIVERSITY OF TOLEDO, OH$458,998ZRG1
2025Extracellular Vesicles from Enterocytes are Mediators of Inflammation in IBD1R15DK142149-01A1MIKLAVCIC, JOHNCHAPMAN UNIVERSITY, CA$458,047DHMI
2025Dissecting the mechanisms through which Wnt5 signaling influences hematopoiesis1R15HL177689-01 · under PAR-21-155GIRARD, JULIETUNIVERSITY OF MASSACHUSETTS BOSTON, MA$457,500ZRG1
2025Developing imaging tools to improve endolysin activity1R15GM160937-01WILLIAMS, SIERRASCRIPPS COLLEGE, CA$457,088ZRG1
2025Control of Polarized Basement Membrane Secretion in Epithelial Cells2R15GM137236-02 · under PAR-21-155DEVERGNE, OLIVIERNORTHERN ILLINOIS UNIVERSITY, IL$455,997ZRG1
2025Mechanisms of Peripheral Nerve Injury and Recovery in a Zebrafish Demyelination Model1R15NS141049-01 · under PAR-21-155PETERSEN, SARAHKENYON COLLEGE, OH$454,424CMBG
2025FGFR1 Signaling in AgRP Neurons for Regulating Metabolism1R15DK139539-01A1 · under PAR-21-155HUANG, HUEAST CAROLINA UNIVERSITY, NC$453,000BMDM
2025High-throughput Identification and Validation of Drugs to Target Migrating and Treatment-Resistant Glioblastoma Cells1R15CA290638-01A1 · under PAR-21-155KIM, YOUNG-TAEUNIVERSITY OF TEXAS ARLINGTON, TX$451,996ZRG1
2025Exploiting a new endoplasmic reticulum targeting BODIPY-Scaffold for detection of organelle stress and exploration of chemotherapeutic transport1R15CA290578-01A1KRUPA, KRISTEN ASWAVEY, SHAWN MICHAELUNIVERSITY OF DAYTON, OH$451,131IPCA
2025VS-EDGE: Visual-Semantic Explanations for Diagnostic Guidance1R15CA297521-01 · under PAR-21-155RAICU, DANIELA STANDE PAUL UNIVERSITY, IL$449,595EITA
2025Calcium regulation and outer hair cell sensitivity to cochlear injury1R15DC022073-01 · under PAR-21-155SIMMONS, DWAYNE DBAYLOR UNIVERSITY, TX$448,687AUD
2025Structure, Function, and Dynamics of Non-Canonical Stress Granules1R15GM157697-01 · under PAR-21-155FARNY, NATALIE GILKSWORCESTER POLYTECHNIC INSTITUTE, MA$445,873ZRG1
2025ENHANCEMENT OF BBB CROSSING OF AR DEGRADERS IN GBM2R15NS116766-02 · under PAR-21-155SU, BINCLEVELAND STATE UNIVERSITY, OH$445,500ZRG1
2025Chemoenzymatic Semisynthesis of Proteoglycan and Its Cofactor Activities1R15HL177621-01 · under PAR-21-155SUN, XUE-LONGCLEVELAND STATE UNIVERSITY, OH$445,500CSB
2025Novel mitochondria-targeting peptides (MTPs) as therapeutic intervention in Barth syndrome1R15HL177692-01 · under PAR-21-155SANDLERS, YANA ICLEVELAND STATE UNIVERSITY, OH$445,500ZRG1
2025Myelination Deficits Underlying Auditory Issues in Fragile X Syndrome2R15HD105231-02A1MCCULLAGH, ELIZABETH ANNEOKLAHOMA STATE UNIVERSITY STILLWATER, OK$444,238ZRG1
2025Unveiling Marine Lanthipeptides: From Biosynthesis to Antibiotic Potential Against Antimicrobial Resistant Pathogens1R15GM159310-01WHALEN, KRISTEN ELIZABETHHAVERFORD COLLEGE, PA$442,710CSB
2025A Spatial and Temporal Analysis of MCH Signaling in the Developing Adipocyte1R15GM157665-01 · under PAR-21-155COOK, LAURIE BCOLLEGE AT BROCKPORT, NY$442,397ZRG1
2025Multiscale anisotropy analysis of breast tissue subtypes from mammography and pathology2R15CA246335-02 · under PAR-21-155KHALIL, ANDREUNIVERSITY OF MAINE ORONO, ME$440,561ZRG1
2025Characterization of a novel chimeric autoantigen receptor (CAAR) treatment for Graves' disease1R15AI183096-01A1WEBER, K. SCOTTBRIGHAM YOUNG UNIVERSITY, UT$440,333MAI
2025Using catalyst speciation to control reactivity and address longstanding challenges in cross coupling reactions1R15GM159334-01MICHAELIS, DAVID JOHNBRIGHAM YOUNG UNIVERSITY, UT$439,203CSB
2025Signal-dependent regulation of cardiac progenitor proliferation1R15HL173851-01A1 · under PAR-21-155DAVIDSON, BRADLEY JSWARTHMORE COLLEGE, PA$439,065ZRG1
2025PTEN and gut epithelial physiology1R15CA297583-01 · under PAR-21-155RHEE, SANG HOONOAKLAND UNIVERSITY, MI$439,049DNPD
2025Mechanophenotyping RBC subpopulations in ME/CFS1R15HL177762-01 · under PAR-21-155RAMASUBRAMANIAN, ANAND KSAN JOSE STATE UNIVERSITY, CA$432,431ZRG1
2025RTA-Induced Ubiquitination in KSHV: A CURE-Based Approach to Identify Novel Targets and Small Molecule Inhibitors1R15AI186824-01A1 · under PAR-21-155EHRLICH, ELANA STOWSON UNIVERSITY, MD$430,285HCAC
2025A Stand-alone Simulation Platform for Designing Tissue Engineering Scaffolds to Serve as Bone Graft Substitutes1R15AR084501-01A1YOUSEFI, AMYMIAMI UNIVERSITY OXFORD, OH$430,152ZRG1
2025Dissecting inflammatory outcomes following eCigarette exposure2R15HL152257-02 · under PAR-21-155REYNOLDS, PAUL RBRIGHAM YOUNG UNIVERSITY, UT$428,639ZRG1
2025Accessing Carbon-based S(VI) compounds via Sulfur-Fluorine (SuFEx) Exchange Reactions2R15GM134457-02 · under PAR-21-155BALL, NICHOLAS DPOMONA COLLEGE, CA$428,004CSB
2025Synthesis and Biochemical Evaluation of Ruthenium Compounds1R15GM159331-01ANDERSON, CRAIGBARD COLLEGE, NY$427,016CSB
2025Role of the parasubthalamic nucleus (PSTN) in the central regulation of feeding behavior1R15DK142148-01 · under PAR-21-155CARTER, MATTHEW EWILLIAMS COLLEGE, MA$427,000NIC
2025Rational Design of Artificial Hydrogenases2R15GM131260-03 · under PAR-21-155CHAKRABORTY, SAUMENUNIVERSITY OF MISSISSIPPI, MS$426,202MSFA
2025Cannabis Nexus Initiative II: Cannabis and Heart Rate Variability Study in HBCU Students2R15DA052886-02 · under PAR-21-155KEEN, LARRY DVIRGINIA STATE UNIVERSITY, VA$420,388ARM
2025An investigation of hyperglycemia-induced region-specific changes in brain metabolism and behavior1R15MH139024-01 · under PAR-21-155VICHAYA, ELISABETH GOODBAYLOR UNIVERSITY, TX$420,000PMDA
2025Type 1 Diabetes: Dyadic Health Behaviors and Communal Coping as Predictors of Glycemic Control Among Emerging Adult Couples1R15DK142163-01 · under PAR-21-155YORGASON, JEREMY B.BRIGHAM YOUNG UNIVERSITY, UT$419,750CMGC
2025Detecting Fatigue and Assessing Cognitive Performance in Video-Based Meetings: Integration of Lab, Field, and Machine Learning Approaches1R15MH135412-01A1 · under PAR-21-155BARUAH, JONALIKALITA, JUGALTARLETON STATE UNIVERSITY, TX$419,534HCMF
2025Prepare Bioanalytical Aptamer Tools and Train Next-generation Scientists for SARS-CoV-31R15AI183190-01A1 · under PAR-21-155TAN, XIAOHONGBOWLING GREEN STATE UNIVERSITY, OH$419,466CBP
2025Therapeutic Mechanisms of Farnesol in Modulating Gut Dysbiosis and Neuroinflammation in Multiple Sclerosis1R15AI191202-01OCHOA-REPARAZ, JAVIERBOISE STATE UNIVERSITY, ID$418,493DNPD
2025Enhancing the Force Validated Heart Valve Surgical Planning Tool1R15HL177711-01 · under PAR-21-155JENSEN, MORTEN OLGAARDUNIVERSITY OF ARKANSAS AT FAYETTEVILLE, AR$414,982ZRG1
2025Inteins: Expanding Biological Roles and Biotechnological Applications2R15GM143662-02LENNON, CHRISTOPHER WILLIAMMURRAY STATE UNIVERSITY, KY$411,683ZRG1
2025Stratifying thrombosis risk in Kawasaki Disease using hemodynamic analysis beyond the z-score1R15HL181586-01HATOUM, HODAMICHIGAN TECHNOLOGICAL UNIVERSITY, MI$410,956HTBT
2025Evaluating the effect of physical activity on sleep disruption and subclinical cardiovascular disease risk in peri- and early postmenopausal women.2R15HL145650-02A1 · under PAR-21-155WITKOWSKI, SARAHSMITH COLLEGE, MA$408,656ZRG1
2025Dual localization of angiopoietin like protein 4 in the extracellular milieu and nucleus regulates the hematogenous brain metastasis of triple negative breast cancer1R15CA287303-01A1 · under PAR-21-155BAILEY, TAMEKA ARNETTARKANSAS STATE UNIVERSITY, AR$408,259ZRG1
2025Examining the mediating and moderating factors in the relationships between social media engagement and ENDS use and dependence among young adults1R15CA290615-01A1 · under PAR-21-155YANG, QINGHUATEXAS CHRISTIAN UNIVERSITY, TX$407,581LHB
2025Expanding the Facets of Multi-Functional Antioxidant Molecules Through Computational Design and Biological Tools2R15GM123463-03AKKARAJU, GIRIDHARCHUMLEY, MICHAEL JGREEN, KAYLA NJANESKO, BENJAMIN G.TEXAS CHRISTIAN UNIVERSITY, TX$406,882CSB
2025A Novel, Low-Cost, Machine Learning based and Wearable Technology for Monitoring Heart Failure Parameters1R15HL175648-01A1KAYA, MEHMETTHIBBOTUWAWA GAMAGE, PESHALAFLORIDA INSTITUTE OF TECHNOLOGY, FL$406,221CIDH
2025Hormonal Contraceptives and Mental Health: Synthetic Hormone Influences on Fear Behavior, Neurocircuitry, and the Gut Microbiome1R15MH140275-01MAENG, LISAUNIVERSITY OF MASSACHUSETTS BOSTON, MA$406,073BNRS
2025Investigation of the Properties of Liquids in the Porous Networks of Macromolecular Crystals2R15GM090248-03 · under PAR-21-155JUERS, DOUGLAS HENRYWHITMAN COLLEGE, WA$404,329MSFB
2025Expression of High-Activity and High-SpecificityMicrobial L-Asparaginases from Naturally Occurring Microorganisms in the Alabama Black Belt1R15GM154270-01A1 · under PAR-21-155OKEKE, BENEDICT CAUBURN UNIVERSITY AT MONTGOMERY, AL$403,640CSB
2025Genetic Regulation of Stress Responses at the Endoplasmic Reticulum1R15GM157704-01 · under PAR-21-155DAHLBERG, CAROLINE LUNDWESTERN WASHINGTON UNIVERSITY, WA$401,429ZRG1
2025Sex Difference in Cocaine-Induced Impulsivity: Contribution of the Mesocorticolimbic Dopamine System and Estradiol1R15DA060396-01A1PAINE, TRACIE ANNOBERLIN COLLEGE, OH$400,836BRLE
2025Optimization of cannabidiol-based formulations in autism spectrum disorder1R15NS141197-01 · under PAR-21-155KAPLAN, JOSHWESTERN WASHINGTON UNIVERSITY, WA$396,988DBD
2025Cellular mechanisms of forgetting a long-term memory2R15MH107892-03 · under PAR-21-155CALIN-JAGEMAN, IRINA ELENACALIN-JAGEMAN, ROBERT JOSEPHDOMINICAN UNIVERSITY, IL$392,062LMDN
2025Identifying social computational phenotypes in mental health1R15MH138992-01 · under PAR-21-155STANLEY, DAMIAN ALEXANDERADELPHI UNIVERSITY, NY$388,026APDA
2025Cannabinoid Tolerance Across Neurodevelopment: Disruption of Value-Driven Behavior and Prevention Through Physical Activity1R15DA063975-01OLESON, ERIK BENJAMINUNIVERSITY OF COLORADO DENVER, CO$385,638BRLE
2025The effect of circadian-disrupting environments on sleep and binge-like eating behavior.1R15HL178082-01A1BOUTRIN, MARIE-CLAIRESIMMONDS RICHARDSON, MELISSAOAKWOOD COLLEGE, AL$385,033BNRS
2025Characterizing the functions of a putative DNA N6-adenine methylation demethylase AtALKBH4 in plants1R15GM159255-01XIAO, WENYANSAINT LOUIS UNIVERSITY, MO$385,000ZRG1
2025Synthesis and Pharmacological Evaluation of 5-Hydroxy-2-(2- phenylethyll)chromone Analogues1R15GM157720-01 · under PAR-21-155WILLIAMS, DWIGHT AKALAMAZOO COLLEGE, MI$384,609CBP
2025Promoting resilience and mechanisms underlying emotion and cardiovascular health as a function of adolescent social stress1R15HL179691-01GRIPPO, ANGELA JNORTHERN ILLINOIS UNIVERSITY, IL$380,000MESH
2025A mechanistic approach to understand the tissue-specific development of toxicity in response totransgenerational chronic arsenic exposures1R15ES037123-01 · under PAR-21-155ROY CHOWDHURY, PRIYANKAKEENE STATE COLLEGE, NH$379,504EDD
2025Ionizable Triazine Lipids for RNA Delivery1R15GM159302-01FUNK, TIMOTHY WILLIAMGETTYSBURG COLLEGE, PA$365,616ZRG1
2025Bioconjugations Employing Unnatural Amino Acids2R15GM113203-03A1YOUNG, DOUGLASCOLLEGE OF WILLIAM AND MARY, VA$358,279CSB
2025Morphological and molecular identification of Hyalomma tick vectors of Crimean-Congo Hemorrhagic Fever virus1R15AI188251-01A1APANASKEVICH, DMITRY AGEORGIA SOUTHERN UNIVERSITY, GA$355,000TVZ
2025Activity-based protein profiling of the human rhomboid proteases for inhibitor discovery and enzyme characterization2R15GM146210-02PARSONS, WILLIAM HAZENOBERLIN COLLEGE, OH$353,705CBP
2025Metabolic Adaptations to Acute and Chronic Exercise1R15HL177624-01A1KOLWICZ, STEPHEN CURSINUS COLLEGE, PA$349,728ZRG1
2025Redox Properties and Partners of the Yeast Thioredoxin Reductase Trr11R15GM151680-01A1 · under PAR-21-155WEST, JAMES DCOLLEGE OF WOOSTER, OH$316,797MSFA
2025Genome topology in the filamentous fungus Neurospora crassa: organizing factors and impact on genome function2R15GM140396-02KLOCKO, ANDREW DAVIDUNIVERSITY OF COLORADO, CO$186,250ZRG1
2025Mechanisms and Consequences of Nucleic Acid Sensing in Erythroid Progenitors1R15AI188361-01 · under PAR-21-155CLEMENTS, REBECCA LYNNSWARTHMORE COLLEGE, PA$74,108BBHV
2024Phospholipid metabolism in Leishmania2R15AI156746-02 · under PAR-21-155ZHANG, KAITEXAS TECH UNIVERSITY, TX$498,722PTHE
2024Investigating the role of helix-1 in the fibrillization of SAA1-761R15GM155857-01 · under PAR-21-155DESAMERO, RUEL Z BYORK COLLEGE, NY$496,648MSFB
2024ELUCIDATING THE FUNCTION OF P53-MEDIATED IL17RB REPRESSION1R15CA287406-01 · under PAR-21-155ZHU, YANST. JOHN'S UNIVERSITY, NY$492,000ZRG1
2024Novel pseudo-differential methods to drastically increase computational speed and accuracy for biomedical ultrasound imaging and focusing1R15EB035359-01A1 · under PAR-21-155KHAJAH, TAHSINUNIVERSITY OF TEXAS TYLER, TX$481,440ITD
2024Repression of inflammasome by Francisella tularensis2R15AI107698-04 · under PAR-21-155MALIK, MEENAKSHIALBANY COLLEGE OF PHARMACY, NY$480,000ZRG1
2024Probiotic neuroimmune modulation of morphine tolerance1R15DA058187-01A1 · under PAR-21-155WHISTLER, CHERYL ALLYNEUNIVERSITY OF NEW HAMPSHIRE, NH$479,535ZRG1
2024Development of Tailored, Multilevel Cervical Cancer Interventions for Ethnically Diverse Black Women1R15CA294297-01 · under PAR-21-155AMUTA, ANN OYAREUNIVERSITY OF TEXAS ARLINGTON, TX$477,869HHD
2024The effects of biological sex, intolerance of uncertainty and anxious states on threat acquisition and extinction learning1R15MH134219-01A1 · under PAR-21-155JOHNSON, DAVID CHARLESYORK COLLEGE, NY$475,572APDA
2024Implicating the major G-quadruplex helicase, DHX36, as a novel pathogenic modifier of C9ORF72 frontal temporal dementia2R15AG067291-02 · under PAR-21-155SMALDINO, PHILIP JBALL STATE UNIVERSITY, IN$475,516CMND
2024Attention and memory contributions to the maintenance of binge eating1R15MH137623-01 · under PAR-21-155JOHNSON, JEFFREY SCOTTNORTH DAKOTA STATE UNIVERSITY, ND$470,808APDA
2024BITE (Bat Immunology Training and Education) - an undergraduate experiential program for developing the next generation of One Health scientists1R15AI180994-01 · under PAR-21-155THOMPSON, CODY WELFORDWHITE III, RICHARD ALLENUNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$470,518CMIA
2024The Role of HA Remodeling and Mesenchymal Transitions in Glioblastoma1R15CA274344-01A1 · under PAR-21-155CHEN, JOSEPHUNIVERSITY OF LOUISVILLE, KY$469,500ZRG1
2024Mitochondrial-targeting Exosomes for Neuroinflammation1R15EB035866-01 · under PAR-21-155BI, LANRONGMICHIGAN TECHNOLOGICAL UNIVERSITY, MI$469,500ZRG1
2024Modulation of host chromatin dynamics and gene expression by viral biomolecular condensates1R15AI183280-01 · under PAR-21-155MAY, JARED PAULUNIVERSITY OF MISSOURI KANSAS CITY, MO$469,500VDT
2024Cell-cell signaling and pattern formation in yeast1R15GM154311-01A1 · under PAR-21-155HONIGBERG, SAUL MUNIVERSITY OF MISSOURI KANSAS CITY, MO$469,500ZRG1
2024Investigation of Molybdenum Cofactor through Chemical, Biochemical and Biophysical Studies2R15GM139064-02 · under PAR-21-155BASU, PARTHAINDIANA UNIVERSITY INDIANAPOLIS, IN$469,170MSFA
2024Mechanoregulation of E-cadherin Adhesion2R15GM116082-03 · under PAR-21-155MARUTHAMUTHU, VENKATOLD DOMINION UNIVERSITY, VA$468,958ZRG1
2024Improving Artificial Intelligence Readiness of RNA Motif Data for Structure Analysis and Modeling1R15GM155891-01 · under PAR-21-155HOU, JIESAINT LOUIS UNIVERSITY, MO$467,334MSFB
2024Body heat activated, storable, near-infrared, self-illuminating nanoprobes for chemiluminescence imaging of cancer1R15DE034720-01A1 · under PAR-21-155LEE, JUNG-JAEUNIVERSITY OF COLORADO DENVER, CO$466,500IPCA
2024Understanding cell chirality and cell-cell interactions at neurovascular unit after brain injury1R15NS139138-01 · under PAR-21-155ZHANG, ZHIUNIVERSITY OF MICHIGAN AT DEARBORN, MI$465,752CMBG
2024Chaperoning Preassembly Modules for Mitochondrial Ribosome Assembly1R15GM155795-01 · under PAR-21-155HENRY, MICHAELROWAN UNIVERSITY, NJ$463,083ZRG1
2024Functional Hybrid Natural Product Synthases by Tracking Acyl Carrier Protein Binding and Conformational Dynamics2R15GM120704-03 · under PAR-21-155CHARKOUDIAN, LOUISE KARINEHAVERFORD COLLEGE, PA$462,351MSFA
2024Neuroprotection for chemotherapy induced peripheral neuropathy1R15CA290570-01 · under PAR-21-155YANG, IN HONGUNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$462,000NOMD
2024A Single-Sided Magnetic Particle Imaging Scanner for In Vivo Breast Cancer Imaging2R15EB028535-03 · under PAR-21-155TONYUSHKIN, ALEXEY AOAKLAND UNIVERSITY, MI$461,895ITD
2024Using Event Momentary Assessment and Actigraphy to Investigate Mediating and Moderating Processes of Discrimination's Negative Effect onSleep1R15HL172210-01A1 · under PAR-21-155KUNSTMAN, JONATHANAUBURN UNIVERSITY AT AUBURN, AL$460,920MESH
2024Determining the impact of cargo membrane fluidity on motor protein function2R15GM120682-03 · under PAR-21-155XU, JINGUNIVERSITY OF CALIFORNIA, MERCED, CA$460,552BBM
2024Utilizing Bioprinted Human Stem Cells for Molecular Screening via Multi-Material Strategies1R15EB036822-01 · under PAR-21-155SUH, WON HYUKUNIVERSITY OF NEW HAMPSHIRE, NH$460,500ZRG1
2024Enhancing Vaccine Thermostability with Natural Deep Eutectic Solvents1R15GM153057-01 · under PAR-21-155MIRJAFARI, ARSALANCOLLEGE AT OSWEGO, NY$459,551ZRG1
2024Distributed approaches to train machine learning models in diabetic retinopathy1R15EY035804-01 · under PAR-21-155ALAM, MINHAJ NURUNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$459,516CDMA

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