The notices it replaced
- Reissues: PAR-19-367 Maximizing Investigators' Research Award (R35 - Clinical Trial Optional)
- 2 steps back: PAR-17-094 Maximizing Investigators' Research Award (R35)
Replaced by PAR-26-121.
Who won it before
2,397 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $1,163,211,459 in first-year total cost, median $433,125.
Most frequent study sections
- Maximizing Investigators' Research Award C Study Section[MRAC]268
- Maximizing Investigators’ Research Award B Study Section[MRAB]200
- Special Emphasis Panel[ZRG1 CB-J (55)]200
- Maximizing Investigators? Research Award A Study Section[MRAA]186
- Maximizing Investigators' Research Award - E Study Section[MRAE]144
Most frequent institutions
- UNIVERSITY OF MICHIGAN AT ANN ARBOR74
- UNIV OF NORTH CAROLINA CHAPEL HILL63
- JOHNS HOPKINS UNIVERSITY59
- STANFORD UNIVERSITY56
- UNIVERSITY OF PENNSYLVANIA51
| FY | Project | PIs | Institution | First-year cost | Study section |
|---|---|---|---|---|---|
| 2025 | Decoding Positional Epigenetic Memory1R35GM158209-01 | MAZZONI, ESTEBAN ORLANDO | NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY | $3,125,817 | MRAA |
| 2025 | Unveiling Hidden Signatures in Life by Vibrational Photothermal Microscopy2R35GM136223-06 | CHENG, JI-XIN | BOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA | $2,811,668 | ZRG1 |
| 2025 | The role of the ribosome and translation factors in mediating stress signaling1R35GM158294-01 | ZAHER, HANI | WASHINGTON UNIVERSITY, MO | $2,777,852 | MRAF |
| 2025 | tRNA in codon usage2R35GM134931-06 | HOU, YA-MING | THOMAS JEFFERSON UNIVERSITY, PA | $2,730,000 | MRAF |
| 2025 | Sample Multiplexing as a Key Enabling Technology for Quantitative Proteomics1R35GM158136-01 | GYGI, STEVEN P | HARVARD MEDICAL SCHOOL, MA | $2,527,500 | ZRG1 |
| 2025 | An integrative structural biology approach to understanding metabolite recognition by cellular receptors2R35GM125034-07 | SGOURAKIS, NIKOLAOS | CHILDREN'S HOSP OF PHILADELPHIA, PA | $2,447,500 | MRAE |
| 2025 | Structure and Function of Protein Disorder in Membrane Trafficking and Organization2R35GM136686-06 | ELIEZER, DAVID | WEILL MEDICAL COLL OF CORNELL UNIV, NY | $2,427,082 | MRAB |
| 2025 | Multifunctional morphogens: patterning precision and mesoderm migration2R35GM138346-06 | HEEMSKERK, IDSE JOANNES | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $2,271,279 | ZRG1 |
| 2025 | Next-generation imaging to interrogate biological systems across time and space1R35GM158040-01 | LEGANT, WESLEY R. | UNIV OF NORTH CAROLINA CHAPEL HILL, NC | $2,257,345 | ZRG1 |
| 2025 | Molecular genetic dissection of tube morphogenesis in the Drosophila tracheal system1R35GM158364-01 | GHABRIAL, AMIN S | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $2,250,542 | MRAC |
| 2025 | Structural biology of DNA damage response in chromatin2R35GM136262-06 | MER, GEORGES | MAYO CLINIC ROCHESTER, MN | $2,219,250 | MRAE |
| 2025 | Molecular Basis of Centromere Specification and Inheritance2R35GM134920-06 | LI, FEI | NEW YORK UNIVERSITY, NY | $2,213,750 | MRAC |
| 2025 | Defining the Rules for Pioneer Factor Nucleosome Engagement1R35GM158384-01 | BUCK, MICHAEL JOSEPH | STATE UNIVERSITY OF NEW YORK AT BUFFALO, NY | $2,203,340 | MRAA |
| 2025 | Quantifying Physiologic and Pathologic Viscoelastic Phases of Biomolecular Condensates by Correlative Force and Fluorescence Microscopy2R35GM138186-06 | BANERJEE, PRIYA R. | STATE UNIVERSITY OF NEW YORK AT BUFFALO, NY | $2,161,607 | ZRG1 |
| 2025 | Molecular mechanisms of ribosome-mediated kinase signaling1R35GM156244-01 | GREEN, RACHEL | JOHNS HOPKINS UNIVERSITY, MD | $2,136,693 | MRAF |
| 2025 | Developmental regulation of oscillatory expression1R35GM158157-01 | AMACHER, SHARON L | OHIO STATE UNIVERSITY, OH | $2,130,924 | MRAC |
| 2025 | The genetic basis of complex traits: from yeast to humans1R35GM156526-01 | FRASER, HUNTER B | STANFORD UNIVERSITY, CA | $2,117,247 | MRAA |
| 2025 | The Architectures and Underpinnings of Adaptive Evolution and Reproductive Isolation2R35GM136306-06 | POOL, JOHN E | UNIVERSITY OF WISCONSIN-MADISON, WI | $2,088,435 | MRAA |
| 2025 | Small molecule signaling in regulation of gut microbiota structure and colonization resistance1R35GM158026-01 | HSIAO, ANSEL | UNIVERSITY OF CALIFORNIA RIVERSIDE, CA | $2,065,745 | MRAF |
| 2025 | Mechanisms of Left Right Organizer Development1R35GM158119-01 | HEHNLY, HEIDI | SYRACUSE UNIVERSITY, NY | $2,055,625 | MRAC |
| 2025 | Multiscale Simulation of Key Biomolecular Processes in the Cell1R35GM158238-01 | VOTH, GREGORY A. | UNIVERSITY OF CHICAGO, IL | $1,970,835 | MRAB |
| 2025 | Computational approaches for elucidating proteomes and interactomes1R35GM158278-01 | SINGH, MONA | PRINCETON UNIVERSITY, NJ | $1,968,575 | MRAA |
| 2025 | Unlocking Biologically-Relevant Opportunities Through Applications of Excited-State Aromaticity and Antiaromaticity2R35GM133548-06 | WU, JUDY I-CHIA | UNIVERSITY OF HOUSTON, TX | $1,962,500 | MRAE |
| 2025 | On differentiating selective and neutral evolutionary processes2R35GM139383-06 | JENSEN, JEFFREY D | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ | $1,768,213 | MRAA |
| 2025 | Chromosome organization and function in time and space: meiosis, mitosis and E. coli2R35GM136322-06 | KLECKNER, NANCY E | HARVARD UNIVERSITY, MA | $1,110,887 | MRAA |
| 2025 | Mechanisms controlling cellular actin dynamics and cytoskeletal crosstalk2R35GM134895-06 | GOODE, BRUCE L | BRANDEIS UNIVERSITY, MA | $1,076,381 | MRAD |
| 2025 | Mechanisms of Cell Regulation and Manipulation by the Ubiquitin System2R35GM136325-06 | HOCHSTRASSER, MARK W | YALE UNIVERSITY, CT | $988,057 | MRAC |
| 2025 | Photoredox Catalysis Applications in Organometallics and Chemical Biology2R35GM134897-06 | MACMILLAN, DAVID W | PRINCETON UNIVERSITY, NJ | $984,000 | MRAB |
| 2025 | Accurate Molecular Decision Making during Protein Biogenesis2R35GM136321-06 | SHAN, SHU-OU | CALIFORNIA INSTITUTE OF TECHNOLOGY, CA | $972,810 | MRAB |
| 2025 | Group II Intron and Related Reverse Transcriptases2R35GM136216-06 | LAMBOWITZ, ALAN M. | UNIVERSITY OF TEXAS AT AUSTIN, TX | $914,003 | MRAA |
| 2025 | Regulation of proliferation and differentiation in the male germ line adult stem cell lineage2R35GM136433-06 | FULLER, MARGARET T | STANFORD UNIVERSITY, CA | $904,601 | MRAC |
| 2025 | Dynamics of the Bacterial Ribosome and Proteome2R35GM136412-06 | WILLIAMSON, JAMES R | SCRIPPS RESEARCH INSTITUTE, THE, CA | $895,950 | MRAE |
| 2025 | Enantioselective and site-selective C-H activation reactions with Bifunctional ligands1R35GM158311-01 | YU, JIN-QUAN | SCRIPPS RESEARCH INSTITUTE, THE, CA | $874,000 | MRAE |
| 2025 | Catalytic and Regulatory Mechanisms of Heme-based Dioxygenases1R35GM156326-01 | YEH, SYUN-RU | ALBERT EINSTEIN COLLEGE OF MEDICINE, NY | $861,420 | ZRG1 |
| 2025 | Genetic control of developmental timing2R35GM131741-06 | AMBROS, VICTOR | UNIV OF MASSACHUSETTS MED SCH WORCESTER, MA | $844,267 | MRAC |
| 2025 | Mechanisms of Helicases, Translocases and SSB Proteins involved in Genome Maintenance2R35GM136632-06 | LOHMAN, TIMOTHY M | WASHINGTON UNIVERSITY, MO | $843,965 | MRAB |
| 2025 | Dissecting the Mechanisms of Regulation and Quality Control in Ribosome Assembly and the Consequences of their Failure2R35GM136323-08 | KARBSTEIN, KATRIN | VANDERBILT UNIVERSITY, TN | $804,521 | MRAA |
| 2025 | Mechanisms of Post-transcriptional Gene Regulation by RNA Binding Proteins2R35GM136426-06 | BLACK, DOUGLAS L | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $801,043 | MRAA |
| 2025 | Functional Characterization of LncRNAs Involved in Pluripotency or Differentiation2R35GM131833-06 | SPECTOR, DAVID L | COLD SPRING HARBOR LABORATORY, NY | $791,040 | MRAF |
| 2025 | Structure and function of phospholipids and inositol phosphates in the nucleus.1R35GM156389-01 | BLIND, RAYMOND DANIEL | VANDERBILT UNIVERSITY MEDICAL CENTER, TN | $778,444 | MRAB |
| 2025 | The Physiology of Oxidative Stress in Bacteria1R35GM158067-01 | IMLAY, JAMES A. | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL | $761,271 | MRAF |
| 2025 | Designer Molecular Probes for Biomedical Applications2R35GM131907-06 | DMOCHOWSKI, IVAN JULIAN | UNIVERSITY OF PENNSYLVANIA, PA | $741,257 | ZRG1 |
| 2025 | Molecular and Cellular Mechanisms of Bacterial Cell Wall Constriction and Chromosome Organization2R35GM136436-06 | XIAO, JIE | JOHNS HOPKINS UNIVERSITY, MD | $740,660 | MRAF |
| 2025 | Molecular Biophysics of Mitochondrial Membranes2R35GM136415-07 | KIRICHOK, YURIY | WASHINGTON UNIVERSITY, MO | $738,625 | MRAD |
| 2025 | Phosphoinositide Signaling in Cytosol and Nucleus2R35GM134955-06 | ANDERSON, RICHARD A. | UNIVERSITY OF WISCONSIN-MADISON, WI | $733,559 | MRAD |
| 2025 | Reconstitution and biophysical study of chromosome segregation machinery2R35GM134842-06 | ASBURY, CHARLES L | UNIVERSITY OF WASHINGTON, WA | $727,855 | MRAC |
| 2025 | Mechanisms of Human DNA Double-Strand Break Repair via Quantitative Single-Molecule Imaging2R35GM134947-06 | ROTHENBERG, ELI | NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY | $726,555 | MRAF |
| 2025 | Role of histone PTMs in epigenetic control of metazoan transcription and RNA processing2R35GM136435-06 | MATERA, A. GREGORY | UNIV OF NORTH CAROLINA CHAPEL HILL, NC | $725,271 | MRAF |
| 2025 | Building and shaping the apical extracellular matrix2R35GM136315-06 | SUNDARAM, MEERA | UNIVERSITY OF PENNSYLVANIA, PA | $714,094 | MRAC |
| 2025 | Molecular Mechanisms of Cell Cycle Control2R35GM136280-06 | BENANTI, JENNIFER A | UNIV OF MASSACHUSETTS MED SCH WORCESTER, MA | $703,540 | MRAC |
| 2025 | Defining Genome Stability Mechanisms and their Regulation by SUMO and Ubiquitin2R35GM136273-06 | BODDY, MICHAEL N | SCRIPPS RESEARCH INSTITUTE, THE, CA | $699,200 | MRAF |
| 2025 | The Mechanism and Regulation of the Dynein Transport Machinery2R35GM136414-06 | YILDIZ, AHMET | UNIVERSITY OF CALIFORNIA BERKELEY, CA | $698,450 | MRAB |
| 2025 | Addressing the complexity and plasticity of heterotrimeric G protein signaling1R35GM156286-01 | GARCIA-MARCOS, MIKEL | BOSTON UNIVERSITY MEDICAL CAMPUS, MA | $694,875 | MRAC |
| 2025 | Fluorescence tools that illuminate biology and inspire translation2R35GM134963-06 | SCHEPARTZ, ALANNA | UNIVERSITY OF CALIFORNIA BERKELEY, CA | $691,843 | ZRG1 |
| 2025 | Assembly Mechanisms of RNA-Protein Complexes for Genetic Control2R35GM136351-06 | WOODSON, SARAH A. | JOHNS HOPKINS UNIVERSITY, MD | $684,837 | ZRG1 |
| 2025 | Structure and Function of Pentameric Ligand-gated Ion Channels2R35GM134896-06 | CHAKRAPANI, SUDHA | CASE WESTERN RESERVE UNIVERSITY, OH | $684,250 | MRAE |
| 2025 | Regulation and function of multicellular calcium signaling in organ growth and regeneration1R35GM156615-01 | ZARTMAN, JEREMIAH JAMES | UNIVERSITY OF NOTRE DAME, IN | $681,393 | ZRG1 |
| 2025 | Mechanisms of eukaryotic translation and ribosome-associated mRNA surveillance and protein quality control2R35GM122602-06 | PESTOVA, TATYANA V | SUNY DOWNSTATE MEDICAL CENTER, NY | $681,240 | MRAF |
| 2025 | Linking gene and function through comparative genomic and experimental approaches1R35GM156215-01 | DE CRECY-LAGARD, VALERIE A | UNIVERSITY OF FLORIDA, FL | $680,790 | MRAA |
| 2025 | Mechanisms of ribosome assembly1R35GM156426-01 | KLINGE, SEBASTIAN | ROCKEFELLER UNIVERSITY, NY | $678,000 | ZRG1 |
| 2025 | The effects of synaptically released zinc on neuronal processing and brain function2R35GM138023-06 | ANDERSON, CHARLES | WEST VIRGINIA UNIVERSITY, WV | $675,064 | ZRG1 |
| 2025 | Structural mechanisms of multimeric ATPases1R35GM156361-01 | KELCH, BRIAN ANTHONY | UNIV OF MASSACHUSETTS MED SCH WORCESTER, MA | $669,281 | MRAB |
| 2025 | Structural and Functional Studies of Chromatin1R35GM158165-01 | HALIC, MARIO | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN | $667,480 | MRAE |
| 2025 | Emergent mechanics of mammalian chromosome segregation2R35GM136420-06 | DUMONT, SOPHIE | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $667,215 | MRAC |
| 2025 | Epigenetic regulations of DNA and histone methylation and deMethylation: Structures and Mechanisms2R35GM134744-06 | CHENG, XIAODONG | UNIVERSITY OF TX MD ANDERSON CAN CTR, TX | $660,050 | MRAF |
| 2025 | Phages as Lenses to Study Virus Assembly and Virus: Host Interactions1R35GM156358-01 | TESCHKE, CAROLYN M | UNIVERSITY OF CONNECTICUT STORRS, CT | $659,949 | MRAE |
| 2025 | Dissection of the TORC1 Signaling Network in Yeast1R35GM158300-01 | CAPALDI, ANDREW PAUL | UNIVERSITY OF ARIZONA, AZ | $659,591 | MRAC |
| 2025 | Control of actin filament networks by Arp2/3 complex and its regulators2R35GM136319-06 | NOLEN, BRADLEY J | UNIVERSITY OF OREGON, OR | $659,275 | MRAD |
| 2025 | Effects of ions on mRNA elements, ribosomes and antibiotic-RNA interactions1R35GM156585-01 | SANBONMATSU, KARISSA Y | TRIAD NATIONAL SECURITY, LLC, NM | $658,165 | MRAE |
| 2025 | Characterizing the molecular mechanisms of centriole duplication and elongation2R35GM136265-06 | ROGERS, GREGORY CHARLES | UNIVERSITY OF ARIZONA, AZ | $657,994 | MRAC |
| 2025 | The Logic of Aptamer Isolation1R35GM158246-01 | STOJANOVIC, MILAN N | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $654,950 | MRAB |
| 2025 | Catalytic Redox Reactions for Pharmaceutical Synthesis2R35GM134929-06 | STAHL, SHANNON S | UNIVERSITY OF WISCONSIN-MADISON, WI | $653,553 | MRAB |
| 2025 | Molecular mechanisms that regulate vesicle formation and transport2R35GM134865-06 | AUDHYA, ANJON | UNIVERSITY OF WISCONSIN-MADISON, WI | $651,492 | MRAD |
| 2025 | Structural and Biochemical Mechanisms of Microtubule Dynamics and Regulation1R35GM156385-01 | RICE, LUKE W | UT SOUTHWESTERN MEDICAL CENTER, TX | $651,001 | ZRG1 |
| 2025 | GTPase Regulation of the Golgi Complex2R35GM136258-06 | FROMME, J CHRISTOPHER | CORNELL UNIVERSITY, NY | $649,673 | MRAB |
| 2025 | Chemical Approaches to Understanding the Mechanisms of Iron-Sulfur Enzymes1R35GM156872-01 | SUESS, DANIEL LEIF MIGDOW | MASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA | $647,301 | ZRG1 |
| 2025 | Variation in chemotactic strategies within and across bacterial species1R35GM158058-01 | EMONET, THIERRY | YALE UNIVERSITY, CT | $645,905 | MRAA |
| 2025 | Diverse Nucleic Acids Chemistry: FundamentalStudies and Applications.2R35GM131736-06 | GREENBERG, MARC M | JOHNS HOPKINS UNIVERSITY, MD | $645,870 | MRAB |
| 2025 | Chemical Strategies to Reveal Cellular Glycation and Ubiquitination1R35GM158376-01 | SCHECK, REBECCA | TUFTS UNIVERSITY MEDFORD, MA | $645,712 | ZRG1 |
| 2025 | PAS proteins: Study and application of signaling mechanisms1R35GM156296-01 | GARDNER, KEVIN H | ADVANCED SCIENCE RESEARCH CENTER, NY | $644,900 | MRAB |
| 2025 | Mapping transient interactions with and on genomic DNA2R35GM134918-06 | SMITH, DUNCAN J | NEW YORK UNIVERSITY, NY | $642,390 | MRAF |
| 2025 | Multiplex Imaging of Signaling Pathways in Cell Motility2R35GM136226-06 | HODGSON, LOUIS | ALBERT EINSTEIN COLLEGE OF MEDICINE, NY | $640,705 | MRAC |
| 2025 | Molecular and Cellular Dynamics in Mammalian Signal Transduction2R35GM136392-06 | AHN, NATALIE G. | UNIVERSITY OF COLORADO, CO | $638,017 | MRAC |
| 2025 | Centromere identity, strength, and regulation2R35GM130302-06 | BLACK, BEN E. | UNIVERSITY OF PENNSYLVANIA, PA | $632,821 | MRAA |
| 2025 | Mitochondrial respiratory chain disease mechanistic and therapeutic modeling2R35GM134863-06 | FALK, MARNI J | CHILDREN'S HOSP OF PHILADELPHIA, PA | $628,340 | MRAD |
| 2025 | Genetic and Molecular Dissection of Wnt Pathway Activation2R35GM136233-06 | AHMED, YASMATH | DARTMOUTH COLLEGE, NH | $627,840 | MRAC |
| 2025 | Molecular mechanisms connecting endocytic and junctional complexes with epithelial pathology in C. elegans1R35GM156633-01 | HOLLOPETER, GUNTHER | CORNELL UNIVERSITY, NY | $627,797 | MRAC |
| 2025 | Elucidating calcineurin signaling mechanisms at membranes2R35GM136243-06 | CYERT, MARTHA S. | STANFORD UNIVERSITY, CA | $621,686 | MRAD |
| 2025 | Structure/Function of Potential Human Cytochrome P450 Drug Targets1R35GM158062-01 | SCOTT, EMILY E | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $620,934 | MRAE |
| 2025 | Data Analysis Tools for Emerging High-throughput Technologies2R35GM131802-06 | IRIZARRY, RAFAEL ANGEL | DANA-FARBER CANCER INST, MA | $620,001 | ZRG1 |
| 2025 | Catalytic Radical Processes for Stereoselective Chemical Synthesis1R35GM156311-01 | ZHANG, X. PETER | BOSTON COLLEGE, MA | $620,000 | ZRG1 |
| 2025 | Uncovering physiological and genomic mechanisms that enable dehydration tolerance in rodents2R35GM128843-06 | MACMANES, MATTHEW DAVID | UNIVERSITY OF NEW HAMPSHIRE, NH | $619,897 | ZRG1 |
| 2025 | Mechanisms of Error-Prone DNA Repair1R35GM158214-01 | LOPARO, JOSEPH J. | HARVARD MEDICAL SCHOOL, MA | $617,007 | MRAB |
| 2025 | Human evolution and the genetic architecture of complex traits1R35GM158240-01 | HERNANDEZ, RYAN D. | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $616,786 | MRAF |
| 2025 | Mechanisms of energy storage in lipid droplets1R35GM158244-01 | FARESE, ROBERT V | SLOAN-KETTERING INST CAN RESEARCH, NY | $609,493 | MRAD |
| 2025 | New Synthetic Methods Enabled by Excited-State Redox Chemistry2R35GM134893-06 | KNOWLES, ROBERT R | PRINCETON UNIVERSITY, NJ | $606,800 | ZRG1 |
| 2025 | Determining how cell growth triggers cell division2R35GM134858-06 | SKOTHEIM, JAN M | STANFORD UNIVERSITY, CA | $606,722 | MRAC |
| 2025 | Structure and Mechanism of G-proteins and cell adhesion proteins in regulation of cell growth and motility2R35GM134962-06 | CAMPBELL, SHARON L | UNIV OF NORTH CAROLINA CHAPEL HILL, NC | $602,153 | MRAE |
| 2025 | The DNA replication-repair interface: mechanisms and regulation2R35GM136401-06 | EICHMAN, BRANDT F | VANDERBILT UNIVERSITY, TN | $600,985 | MRAE |
| 2025 | Helicase Mechanism and G-Quadruplex Signaling1R35GM156702-01 | RANEY, KEVIN DOUGLAS | UNIV OF ARKANSAS FOR MED SCIS, AR | $598,543 | MRAE |
| 2025 | Structural and dynamic studies of protein and protein-nucleic acid assemblies in health and disease1R35GM156238-01 | JARONIEC, CHRISTOPHER P | OHIO STATE UNIVERSITY, OH | $597,573 | MRAB |
| 2025 | A genetically encoded toolset to decipher the biology of post-translational modifications in the mammalian proteome2R35GM136437-06 | CHATTERJEE, ABHISHEK | BOSTON COLLEGE, MA | $596,750 | ZRG1 |
| 2025 | From protein structures to effective drugs via machine learning and molecular simulation1R35GM158122-01 | DROR, RON | STANFORD UNIVERSITY, CA | $590,806 | MRAB |
| 2025 | Control of cell growth and size2R35GM131826-06 | KELLOGG, DOUGLAS R. | UNIVERSITY OF CALIFORNIA SANTA CRUZ, CA | $590,254 | MRAD |
| 2025 | Chemoenzymatic Strategies for Molecular Discovery and Asymmetric Synthesis1R35GM158365-01 | FASAN, RUDI | UNIVERSITY OF TEXAS DALLAS, TX | $585,000 | MRAE |
| 2025 | Spatiotemporal mapping and engineering in the dark proteome1R35GM156806-01 | COWBURN, DAVID | ALBERT EINSTEIN COLLEGE OF MEDICINE, NY | $584,420 | MRAE |
| 2025 | Decoding the rules that govern the coordination of the bacterial cell cycle1R35GM158016-01 | MERA, PAOLA E | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL | $583,698 | MRAA |
| 2025 | Decoding the role of entropy in protein structural stability, dynamics, and function in health and disease1R35GM158127-01 | WAND, A. JOSHUA | TEXAS A&M AGRILIFE RESEARCH, TX | $583,420 | MRAB |
| 2025 | Accelerating Discovery by Merging Kinetics with Data Science Methods in Catalytic Organic Reactions1R35GM158320-01 | BLACKMOND, DONNA G | SCRIPPS RESEARCH INSTITUTE, THE, CA | $582,422 | MRAB |
| 2025 | ATP-driven detection of foreign proteins triggers diverse mechanisms of cellular defense and phage-mediated counter defense2R35GM134867-06 | WIEDENHEFT, BLAKE A | MONTANA STATE UNIVERSITY - BOZEMAN, MT | $582,105 | MRAA |
| 2025 | Signaling and Metabolic Regulation of Nucleotide Metabolism and Cell Growth1R35GM158171-01 | BEN-SAHRA, ISSAM | NORTHWESTERN UNIVERSITY, IL | $577,280 | MRAC |
| 2025 | Molecular Basis for Transmembrane Conduction & Signaling1R35GM156263-01 | STROUD, ROBERT M | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $576,104 | ZRG1 |
| 2025 | The functional organization of mammalian membranes2R35GM134949-07 | LEVENTAL, ILYA | UNIVERSITY OF VIRGINIA, VA | $576,030 | ZRG1 |
| 2025 | Unraveling the molecular interconnections between circadian rhythms and lipid metabolism1R35GM156366-01 | WANG, XUEMIN | UNIVERSITY OF MISSOURI-ST. LOUIS, MO | $574,021 | MRAD |
| 2025 | Understanding general principles in receptor tyrosine kinase signaling through structural and functional studies1R35GM156386-01 | BAI, XIAOCHEN | UT SOUTHWESTERN MEDICAL CENTER, TX | $574,000 | MRAE |
| 2025 | In vivo regulation of cell trafficking and the extracellular matrix2R35GM136236-06 | FAY, DAVID S | UNIVERSITY OF WYOMING, WY | $570,775 | MRAD |
| 2025 | Variant Chromatin Structures-Targeting and Functions1R35GM156364-01 | LUK, EDWARD E | STATE UNIVERSITY NEW YORK STONY BROOK, NY | $568,113 | MRAF |
| 2025 | Nutritional Control of Nematode Development1R35GM156356-01 | BAUGH, LARRY RYAN | DUKE UNIVERSITY, NC | $565,826 | MRAC |
| 2025 | Discovering catalytic activities for pseudoenzymes1R35GM158265-01 | TAGLIABRACCI, VINCENT SCOTT | UT SOUTHWESTERN MEDICAL CENTER, TX | $562,800 | MRAE |
| 2025 | Auxin Response Factors as a model of transcriptional control2R35GM136338-06 | STRADER, LUCIA | SALK INSTITUTE FOR BIOLOGICAL STUDIES, CA | $562,500 | MRAC |
| 2025 | The Role of Dynamics in Regulating Multi-Activity Protein Complexes and Chromatin2R35GM133751-06 | D'ARCY, SHEENA | UNIVERSITY OF TEXAS DALLAS, TX | $562,420 | MRAE |
| 2025 | Discovery and Engineering of RiPP Natural Products1R35GM158411-01 | MITCHELL, DOUGLAS ALAN | VANDERBILT UNIVERSITY, TN | $558,651 | MRAE |
| 2025 | Drivers of adaptation and colonization within individual human microbiomes1R35GM156282-01 | LIEBERMAN, TAMI D | MASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA | $557,900 | MRAF |
| 2025 | Understanding how structural mutations and individual RNA isoforms are involved in human health and disease2R35GM138636-07 | EBBERT, MARK T W | UNIVERSITY OF KENTUCKY, KY | $556,531 | MRAA |
| 2025 | Molecular Mechanisms and Evolution of the Rhoptry Secretion System1R35GM156396-01 | CHANG, YI-WEI | UNIVERSITY OF PENNSYLVANIA, PA | $556,510 | MRAE |
| 2025 | Actin filament mechanics and branched network turnover2R35GM136656-06 | DE LA CRUZ, ENRIQUE M | YALE UNIVERSITY, CT | $555,820 | MRAB |
| 2025 | Selective Transformations of Common Feedstocks to Functionalized Amines and Heterocycles1R35GM158111-01 | ROVIS, TOMISLAV | COLUMBIA UNIV NEW YORK MORNINGSIDE, NY | $552,403 | MRAB |
| 2025 | Genetic regulation of inter- and intra-species microbial community formation1R35GM156045-01 | NOBILE, CLARISSA JANE | UNIVERSITY OF CALIFORNIA, MERCED, CA | $550,108 | ZRG1 |
| 2025 | Structure, Accessibility and Extension of Telomeric Overhangs1R35GM156183-01 | BALCI, HAMZA | KENT STATE UNIVERSITY, OH | $546,146 | MRAB |
| 2025 | Mining Cryptic Biosynthetic Gene Clusters for Novel Bioactive Compounds and Biocatalysts2R35GM138002-06 | PARKINSON, ELIZABETH IVY | PURDUE UNIVERSITY, IN | $544,123 | MRAE |
| 2025 | Mechanical Information Processing from Sub-cellular to Tissue Scales1R35GM156484-01 | GARDEL, MARGARET LISE | UNIVERSITY OF CHICAGO, IL | $541,967 | MRAD |
| 2025 | Probing transcriptional activation at the molecular level2R35GM136356-06 | MAPP, ANNA K. | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $541,353 | MRAE |
| 2025 | Characterizing the Effects of Sequence Variability in Molecular Function, Evolution and Design2R35GM133631-06 | MORCOS, ALONSO FARUCK | UNIVERSITY OF TEXAS DALLAS, TX | $541,096 | ZRG1 |
| 2025 | Macrophage Phenotypes and Tissue Repair2R35GM136228-06 | KOH, TIMOTHY J | UNIVERSITY OF ILLINOIS AT CHICAGO, IL | $540,179 | MRAD |
| 2025 | High-throughput discovery and modeling of protein stability and dynamics1R35GM158118-01 | ROCKLIN, GABRIEL JACOB | NORTHWESTERN UNIVERSITY, IL | $540,000 | MRAE |
| 2025 | Advanced machine learning models to integrate multi-modal biomedical datasets for gene regulation and precision medicine2R35GM133657-07 | BOZDAG, SERDAR | UNIVERSITY OF NORTH TEXAS, TX | $539,986 | ZRG1 |
| 2025 | Protein-based Self-assembly and Disassembly of Nanostructures2R35GM136395-06 | THAYUMANAVAN, SANKARAN | UNIVERSITY OF MASSACHUSETTS AMHERST, MA | $538,897 | ZRG1 |
| 2025 | Harnessing protein clustering to understand, identify, and manipulate cellular systems2R35GM138211-06 | BUGAJ, LUKASZ | UNIVERSITY OF PENNSYLVANIA, PA | $536,106 | ZRG1 |
| 2025 | Structural regulation of Class-I and Class-II cytochrome P450 enzymes2R35GM133375-06 | ESTRADA, DAVID FERNANDO | STATE UNIVERSITY OF NEW YORK AT BUFFALO, NY | $535,979 | MRAE |
| 2025 | The Biology and Biochemistry of Lipid Transfer Protein-Regulated Phosphoinositide Signaling2R35GM131804-06 | BANKAITIS, VYTAS A | TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR, TX | $535,709 | MRAE |
| 2025 | Molecular mechanisms of protein function1R35GM156616-01 | HITE, RICHARD KEVIN | SLOAN-KETTERING INST CAN RESEARCH, NY | $534,160 | MRAE |
| 2025 | UBIQUITIN-PROTEASOME PATHWAY in HUMAN DISEASE1R35GM156397-01 | BEZSONOVA, IRINA | UNIVERSITY OF CONNECTICUT SCH OF MED/DNT, CT | $528,129 | MRAE |
| 2025 | Computational analysis of complex genetic interactions2R35GM133613-06 | MCCANDLISH, DAVID MARTIN | COLD SPRING HARBOR LABORATORY, NY | $528,000 | MRAF |
| 2025 | Spatial control of membrane traffic by septin GTPases2R35GM136337-07 | SPILIOTIS, ELIAS T | UNIVERSITY OF VIRGINIA, VA | $527,873 | MRAD |
| 2025 | Modeling mechanisms in cytokinesis, cell polarization and motility2R35GM136372-06 | VAVYLONIS, DIMITRIOS | LEHIGH UNIVERSITY, PA | $526,805 | ZRG1 |
| 2025 | Structure and mechanism of how cells read and repair the genome1R35GM158347-01 | HE, YUAN | JOHNS HOPKINS UNIVERSITY, MD | $525,416 | MRAB |
| 2025 | Controlled Catalytic Functionalization of Alkenes and Alkynes1R35GM156483-01 | ENGLE, KEARY MARK | SCRIPPS RESEARCH INSTITUTE, THE, CA | $524,400 | MRAE |
| 2025 | Data Science Guided Organic Reaction Development2R35GM136271-06 | SIGMAN, MATTHEW S | UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, UT | $523,685 | MRAE |
| 2025 | New methods for computational modeling of RNA structures2R35GM134919-06 | CHEN, SHI-JIE | UNIVERSITY OF MISSOURI-COLUMBIA, MO | $520,040 | MRAE |
| 2025 | Intracellular Remodeling during Early Development2R35GM131810-06 | YANG, JING | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL | $519,685 | MRAC |
| 2025 | Repetitive sequences drive genome variation and plasticity2R35GM133600-06 | BECK, CHRISTINE R | UNIVERSITY OF CONNECTICUT SCH OF MED/DNT, CT | $516,778 | ZRG1 |
| 2025 | Mechanism and Regulation of DNA Recombination1R35GM158251-01 | IRA, GRZEGORZ A | BAYLOR COLLEGE OF MEDICINE, TX | $516,608 | MRAF |
| 2025 | Regulation of cellular plasticity and regeneration in Drosophila spermatogenesis2R35GM136665-06 | MATUNIS, ERIKA L | JOHNS HOPKINS UNIVERSITY, MD | $515,852 | ZRG1 |
| 2025 | Using naturally evolved phenotypic variation to decipher the positional regulatory code of mammalian skin2R35GM133758-06 | MALLARINO, RICARDO | PRINCETON UNIVERSITY, NJ | $513,550 | ZRG1 |
| 2025 | Mechanisms of Homeodomain Transcription Factor Specificity1R35GM158075-01 | GEBELEIN, BRIAN | CINCINNATI CHILDRENS HOSP MED CTR, OH | $510,390 | MRAF |
| 2025 | Mechanisms of Cell Communication in Animal Development1R35GM156377-01 | ROY, SOUGATA | UNIV OF MARYLAND, COLLEGE PARK, MD | $509,982 | ZRG1 |
| 2025 | A multi-scale systems biology framework for understanding and engineering the human gut microbiome2R35GM124774-06 | VENTURELLI, OPHELIA | DUKE UNIVERSITY, NC | $509,125 | ZRG1 |
| 2025 | Epigenetic gene regulation for stem cell fates1R35GM158393-01 | PENG, JAMY C. | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN | $508,750 | ZRG1 |
| 2025 | Gene regulatory mechanisms driving development during transcriptional silence from oocyte to embryo in mammals1R35GM157073-01 | COOK-ANDERSEN, HEIDI | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $508,315 | MRAC |
| 2025 | Evolutionary and functional genomics of genetic novelties and expression adaptation in Drosophila1R35GM156525-01 | BEGUN, DAVID J | UNIVERSITY OF CALIFORNIA AT DAVIS, CA | $507,000 | MRAA |
| 2025 | Population genomics in laboratory and outbred mouse populations2R35GM133415-06 | DUMONT, BETHANY L | JACKSON LABORATORY, ME | $506,220 | ZRG1 |
| 2025 | Cellular Systems Genetic Approaches to Understanding Regulatory Variation2R35GM133724-06 | BAKER, CHRISTOPHER LEE | JACKSON LABORATORY, ME | $506,220 | MRAA |
| 2025 | Functional dynamics of essential bacterial proteins and EPR technology development1R35GM158260-01 | KLUG, CANDICE S | MEDICAL COLLEGE OF WISCONSIN, WI | $506,105 | MRAE |
| 2025 | Non-coding RNA in stem cell biology1R35GM158281-01 | VAN WOLFSWINKEL, JOSEPHINA C | YALE UNIVERSITY, CT | $504,175 | ZRG1 |
| 2025 | Dissecting the roles of ubiquitin in translation control2R35GM137954-06 | SILVA, GUSTAVO M | DUKE UNIVERSITY, NC | $502,733 | MRAC |
| 2025 | Genomic reprogramming in the early embryo2R35GM136298-06 | HARRISON, MELISSA | UNIVERSITY OF WISCONSIN-MADISON, WI | $502,161 | MRAF |
| 2025 | From humans and eukaryotes to viruses and pathogens; how transition metals shape catalysis and allostery1R35GM156452-01 | PANDELIA, MARIA-EIRINI | BRANDEIS UNIVERSITY, MA | $502,043 | ZRG1 |
| 2025 | Molecular basis for CRISPR-associated transposons and RNA-guided transcriptional regulation1R35GM158248-01 | CHANG, LEIFU | PURDUE UNIVERSITY, IN | $501,917 | MRAB |
| 2025 | Precision Pharmacology and Pharmacovigilance: Leveraging AI to address drug safety knowledge gaps2R35GM131905-07 | TATONETTI, NICHOLAS P | CEDARS-SINAI MEDICAL CENTER, CA | $501,000 | ZRG1 |
| 2025 | Bridging the Gap Between Prediction and Reality in Structural Biology1R35GM158447-01 | HOLTON, JAMES M | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $501,000 | MRAB |
| 2025 | Dynamic modulation of HCN4 and ASICs2R35GM137912-06 | BANKSTON, JOHN | UNIVERSITY OF COLORADO DENVER, CO | $500,940 | MRAB |
| 2025 | Organization of Syncytial Cells1R35GM156800-01 | GLADFELTER, AMY S | DUKE UNIVERSITY, NC | $499,145 | MRAC |
| 2025 | Mechanistic studies of ABC importers in pathogenic bacteria1R35GM158705-01 | PINKETT, HEATHER WENDY | NORTHWESTERN UNIVERSITY, IL | $498,778 | MRAB |
| 2025 | Accessing the hidden biosynthetic capabilities of fungi1R35GM156119-01 | KELLER, NANCY P | UNIVERSITY OF WISCONSIN-MADISON, WI | $495,117 | MRAB |
| 2025 | New Bond Disconnections in the Streamlined Synthesis of Complex Bioactive Molecules1R35GM156482-01 | MAIMONE, THOMAS JOHN | UNIVERSITY OF CALIFORNIA BERKELEY, CA | $493,243 | MRAE |
| 2025 | Structural mechanisms of Scap/SREBP signaling in membrane homeostasis2R35GM136387-06 | ROSENBAUM, DANIEL | UT SOUTHWESTERN MEDICAL CENTER, TX | $492,000 | MRAE |
| 2025 | Molecular Mechanisms Underlying Yeast Transcription Circuit Evolution1R35GM156460-01 | JOHNSON, ALEXANDER D | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $491,739 | MRAA |
| 2025 | Mechanical coordination and mechano-biochemical feedback in epithelial folding1R35GM156319-01 | HE, BING | DARTMOUTH COLLEGE, NH | $490,841 | MRAC |
| 2025 | Cell Fate Decisions in Epithelial Stem Cell Lineages2R35GM136348-06 | NYSTUL, TODD | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $490,192 | MRAC |
| 2025 | Empowering NMR Utilization in Mechanistic Biology: Extending Size Limits and Catalyzing Automation1R35GM158220-01 | ARTHANARI, HARIBABU | DANA-FARBER CANCER INST, MA | $489,500 | MRAB |
| 2025 | Decoding cell surface chemistry and function in Staphylococcus aureus1R35GM156332-01 | CEGELSKI, LYNETTE S | STANFORD UNIVERSITY, CA | $488,783 | MRAB |
| 2025 | Design principles and dynamic gene control in embryonic development2R35GM133425-06 | LIM, BOMYI | UNIVERSITY OF PENNSYLVANIA, PA | $486,806 | ZRG1 |
| 2025 | Defining the genetic architecture of multiple stress response2R35GM133588-06 | SUTPHIN, GEORGE LEWIS | UNIVERSITY OF ARIZONA, AZ | $486,436 | MRAC |
| 2025 | Dynamics of the cellular interactome2R35GM136255-06 | BRUCE, JAMES EDWARD | UNIVERSITY OF WASHINGTON, WA | $485,375 | ZRG1 |
| 2025 | Molecular Mechanisms Underlying E-cadherin Mechanotransduction2R35GM136291-06 | DEMALI, KRIS A | UNIVERSITY OF IOWA, IA | $484,990 | MRAD |
| 2025 | Spatiotemporal Regulation of Organelle Interactions and Metabolism1R35GM158363-01 | KAST, DAVID J | WASHINGTON UNIVERSITY, MO | $484,625 | MRAD |
| 2025 | New Catalytic Methods for the Synthesis of Complex Molecules2R35GM136330-06 | NICEWICZ, DAVID A | UNIV OF NORTH CAROLINA CHAPEL HILL, NC | $484,335 | MRAE |
| 2025 | Evolutionary Tradeoffs in Antibiotic Resistance1R35GM156320-01 | BAYM, MICHAEL | HARVARD MEDICAL SCHOOL, MA | $483,990 | MRAF |
| 2025 | Determining the roles of autophagy in gametogenesis in S. cerevisiae1R35GM156387-01 | WANG, FEI | UT SOUTHWESTERN MEDICAL CENTER, TX | $483,640 | MRAC |
| 2025 | Biochemical Mechanisms of Eukaryotic RNA Processing2R35GM136261-06 | HOSKINS, AARON ANDREW | UNIVERSITY OF WISCONSIN-MADISON, WI | $483,497 | MRAF |
| 2025 | Circadian regulation of cell outputs2R35GM136363-06 | BLAU, JUSTIN | NEW YORK UNIVERSITY, NY | $481,927 | ZRG1 |
| 2025 | The interplay of extracellular fluid viscosity, stiffness and confinement in regulating cell responses1R35GM156305-01 | KONSTANTOPOULOS, KONSTANTINOS | JOHNS HOPKINS UNIVERSITY, MD | $479,487 | ZRG1 |
| 2025 | Patterning acentrosomal microtubule arrays2R35GM133573-06 | YOGEV, SHAUL | YALE UNIVERSITY, CT | $479,050 | ZRG1 |
| 2025 | Tracking transcriptome diversity in real-time2R35GM133762-06 | PAI, ATHMA A | UNIV OF MASSACHUSETTS MED SCH WORCESTER, MA | $479,050 | ZRG1 |
| 2025 | Single Cell Analysis of MAPK Signaling Dynamics in Multicellularity2R35GM133499-06 | REGOT, SERGI | JOHNS HOPKINS UNIVERSITY, MD | $479,038 | ZRG1 |
| 2025 | Mechanisms of cell-autonomous plasma membrane stabilization and repair in plants1R35GM158354-01 | XIAO, SHUNYUAN | UNIV OF MARYLAND, COLLEGE PARK, MD | $478,269 | ZRG1 |
| 2025 | Uncovering new approaches to manipulate and probe biochemical processes with spatial and temporal precision2R35GM136367-06 | TUCKER, CHANDRA L | UNIVERSITY OF COLORADO DENVER, CO | $478,084 | ZRG1 |
| 2025 | Understanding the Mechanisms of Respiratory Supercomplexes and mitochondrial Complex I2R35GM137929-06 | LETTS, JAMES ANTHONY | UNIVERSITY OF CALIFORNIA AT DAVIS, CA | $477,345 | MRAE |
| 2025 | Coordination of chaperone interactions that dictate protein folding and trafficking2R35GM133552-06 | PLATE, LARS | VANDERBILT UNIVERSITY, TN | $475,254 | MRAD |
| 2025 | Mechanisms of Primary Cilium Assembly and Disassembly2R35GM137956-06 | BRESLOW, DAVID KING | YALE UNIVERSITY, CT | $474,444 | MRAC |
Showing the 200 most recent of 2,397 awards.
Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.