The notices it replaced
- Reissues: PAR-21-167 Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed)
- 2 steps back: PAR-19-369 Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed)
- 3 steps back: PA-16-141 Development of Animal Models and Related Biological Materials for Research (R21)
- 4 steps back: PA-13-145 Development of Animal Models and Related Biological Materials for Research (R21)
- 5 steps back: PA-10-138 Development of Animal Models and Related Biological Materials For Research (R21)
- 6 steps back: PA-07-336 Development of Animal Models and Related Biological Materials For Research (R21)
Who won it before
135 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $30,362,311 in first-year total cost, median $228,000.
Most frequent study sections
- Therapeutic Approaches to Genetic Diseases Study Section[TAG]18
- Development - 2 Study Section[DEV2]15
- Development - 1 Study Section[DEV1]7
- Genomics, Computational Biology and Technology Study Section[GCAT]5
- Molecular Neurogenetics Study Section[MNG]5
Most frequent institutions
- JACKSON LABORATORY6
- BAYLOR COLLEGE OF MEDICINE5
- STANFORD UNIVERSITY5
- UNIVERSITY OF MICHIGAN AT ANN ARBOR5
- CINCINNATI CHILDRENS HOSP MED CTR4
| FY | Project | PIs | Institution | First-year cost | Study section |
|---|---|---|---|---|---|
| 2025 | Developing mouse models for functional studies of locus-specific DNA methylation1R21OD038402-01 · under PAR-21-167 | SHEN, LANLAN | BAYLOR COLLEGE OF MEDICINE, TX | $395,450 | MG |
| 2025 | The Mouse Model System for Targeted Trimming of Disease Susceptibility Loci1R21OD038406-01 · under PAR-21-167 | PETUKHOVA, GALINA | HENRY M. JACKSON FDN FOR THE ADV MIL/MED, MD | $261,017 | MG |
| 2025 | Development of a Rat Model to Investigate the Physiology of Telomerase Reverse Transcriptase alternative splicing isoforms1R21OD037663-01A1 · under PAR-21-167 | BEYER, ANDREAS MLUDLOW, ANDREW TODD | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $259,423 | CMAD |
| 2025 | Characterizing a novel mouse model linking sphingolipid metabolism to multi-organ fibrosis1R21OD037868-01 · under PAR-21-167 | SABA, JULIE D | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $246,000 | DBDT |
| 2025 | MOLECULAR AND GENETIC CHARACTERIZATION OF EMS-INDUCED LETHAL MUTATIONS IN DROSOPHILA ENRICHED FOR ORTHOLOGS OF HUMAN DISEASE-CAUSING GENES1R21OD038417-01 · under PAR-21-167 | YAMAMOTO, SHINYA | BAYLOR COLLEGE OF MEDICINE, TX | $240,750 | GCAT |
| 2025 | A Novel Mouse Model for the Detection of Genome Editing1R21OD037647-01A1 · under PAR-21-167 | WALKEY, CHRISTOPHER JOHN | BAYLOR COLLEGE OF MEDICINE, TX | $240,039 | TAG |
| 2025 | Generation and characterization of PET-reporter pigs for noninvasive imaging and cell therapy research1R21OD037856-01 · under PAR-21-167 | TELUGU, BHANU PRAKASH | UNIVERSITY OF MISSOURI-COLUMBIA, MO | $234,750 | TAG |
| 2025 | Development of Transgenic Mouse Model Resources for Red Fluorescence-Based Genetically Encoded Indicator Studies1R21OD037867-01A1 · under PAR-21-167 | BAGHER, POONEHGURUMURTHY, CHANNABASAVAIAH | UNIVERSITY OF NEBRASKA MEDICAL CENTER, NE | $230,250 | ZRG1 |
| 2025 | Defining the ciliary proteomes in vivo1R21OD038399-01 · under PAR-21-167 | YODER, BRADLEY K. | UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL | $222,750 | CSF1 |
| 2025 | A modular system for murine CRISPR genome and epigenome editing1R21OD037909-01A1 · under PAR-21-167 | PU, WILLIAM TSWENCHING | BOSTON CHILDREN'S HOSPITAL, MA | $222,500 | GCAT |
| 2025 | Developing robust genome editing tools for generating floxed alleles and editing amino acid change in zebrafish1R21OD037634-01A1 · under PAR-21-167 | KANG, JUNSU | UNIVERSITY OF WISCONSIN-MADISON, WI | $194,375 | DEV2 |
| 2025 | Development of Mouse Models to Study the Role of Mechanotransduction in Disease Pathogenesis1R21OD037863-01A1 · under PAR-21-167 | RADICE, GLENN LAWRENCE | RHODE ISLAND HOSPITAL, RI | $95,196 | ZRG1 |
| 2024 | Establishing Acomys as a genetic platform for regeneration research1R21OD036471-01 · under PAR-21-167 | MILLEN, KATHLEEN JOYCE | SEATTLE CHILDREN'S HOSPITAL, WA | $293,550 | DEV2 |
| 2024 | Rapid Development of Mouse Resource Strains through the Application of Prime Editors1R21OD037653-01 · under PAR-21-167 | BERGSTROM, DAVID ERIC | JACKSON LABORATORY, ME | $265,500 | GCAT |
| 2024 | Rapid Generation of Transgenic Rhesus Macaques using a Safe-harbor Genomic Docking Site1R21OD037648-01 · under PAR-21-167 | BIMBER, BENJAMINBURWITZ, BENJAMIN J | OREGON HEALTH & SCIENCE UNIVERSITY, OR | $263,250 | TAG |
| 2024 | Identifying non-human primate models for specific human microbiome traits1R21OD033659-01A1 · under PAR-21-167 | AMATO, KATHERINE RYAN | NORTHWESTERN UNIVERSITY, IL | $246,020 | DHMI |
| 2024 | Genetically enabling Hydra oligactis for comparative studies in development, regeneration and aging.1R21OD037741-01 · under PAR-21-167 | JULIANO, CELINA | UNIVERSITY OF CALIFORNIA AT DAVIS, CA | $241,500 | ZRG1 |
| 2024 | A validated mouse model of brown fat targeting1R21OD034470-01A1 · under PAR-21-167 | SANCHEZ-GURMACHES, JUAN | CINCINNATI CHILDRENS HOSP MED CTR, OH | $240,750 | BMDM |
| 2024 | Identifying the radioprotective potential of radiation-resistant fungi using Drosophila1R21OD034471-01A1 · under PAR-21-167 | COX, RACHEL TAFEL | HENRY M. JACKSON FDN FOR THE ADV MIL/MED, MD | $239,363 | RTB |
| 2024 | Novel Knock-in mtDNA Mouse Model to Study Mitochondrial Dysfunction1R21OD037651-01 · under PAR-21-167 | COPPOTELLI, GIUSEPPEROSS, JAIME MARIE | UNIVERSITY OF RHODE ISLAND, RI | $236,250 | CMAD |
| 2024 | The Unilateral Mosaic (UMos): Novel tools to compartmentalize pathology and trace cellular interactions in mouse models of human disease1R21OD037879-01 · under PAR-21-167 | GLUDISH, DAVID W | CORNELL UNIVERSITY, NY | $235,500 | CMT |
| 2024 | Multicolor mouse models to resolve hematopoietic stem and progenitor cells in vivo1R21OD037861-01 · under PAR-21-167 | TAMPLIN, OWEN JAMES | UNIVERSITY OF WISCONSIN-MADISON, WI | $217,533 | BBHV |
| 2024 | Conditional Animal Models of mtDNA Disease1R21OD036173-01 · under PAR-21-167 | EKKER, STEPHEN CARL | UNIVERSITY OF TEXAS AT AUSTIN, TX | $198,750 | TAG |
| 2024 | Deciphering mechanobiology in human diseases by developing a TMEM63B channelopathy mouse model1R21OD037849-01 · under PAR-21-167 | YANG, HUANGHE | DUKE UNIVERSITY, NC | $193,101 | CSF1 |
| 2024 | Targeted ingression of SNPs into the zebrafish genome1R21OD036481-01A1 · under PAR-21-167 | ESSNER, JEFFREY J | IOWA STATE UNIVERSITY, IA | $181,754 | MG |
| 2023 | Novel humanized mouse model of mucosal immunity1R21OD032454-01A1 · under PAR-21-167 | PALUCKA, ANNA KAROLINA | JACKSON LABORATORY, ME | $291,555 | CMIB |
| 2023 | Novel hematopoietic humanized mouse model to study CAR-T therapy-associated cytokine release syndrome1R21OD034476-01 · under PAR-21-167 | FAN, YONG | ALLEGHENY-SINGER RESEARCH INSTITUTE, PA | $249,570 | CIC |
| 2023 | Development of foundational building blocks for stable genetic modification of sea urchin embryos1R21OD034075-01 · under PAR-21-167 | HAMDOUN, AMRO M | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $237,000 | DEV1 |
| 2023 | Danionella cerebrum as a transparent vertebrate adult model for studying immune-related biological processes and diseases1R21OD033664-01A1 · under PAR-21-167 | LAM, PUI YING | MEDICAL COLLEGE OF WISCONSIN, WI | $234,000 | DEV1 |
| 2023 | Establishment of xenopus stem cell lines1R21OD033669-01A1 · under PAR-21-167 | GOUIGNARD, NADEGE | UNIVERSITY OF WISCONSIN MILWAUKEE, WI | $231,000 | DEV1 |
| 2023 | Dissecting out differential molecular phenotypes across Lysine(K) AcetylTransferase mutations in mouse development1R21OD035421-01 · under PAR-21-167 | ARBOLEDA, VALERIE A | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $230,494 | TAG |
| 2023 | CRISPR-Cas13d: Transgenic zebrafish lines toknockdown mRNA1R21OD034161-01 · under PAR-21-167 | BAZZINI, ARIEL | STOWERS INSTITUTE FOR MEDICAL RESEARCH, MO | $206,250 | GCAT |
| 2023 | Illuminating gene therapy1R21OD034078-01 · under PAR-21-167 | MCMANUS, MICHAEL T | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $201,875 | TAG |
| 2023 | A suite of conditional mouse models for secretome labeling1R21OD034455-01 · under PAR-21-167 | LONG, JONATHAN Z | STANFORD UNIVERSITY, CA | $198,226 | EBIT |
| 2023 | Increasing the efficiency and range of prime editing for disease modeling in zebrafish1R21OD033668-01A1 · under PAR-21-167 | SOLNICAKREZEL, LILIANNA | WASHINGTON UNIVERSITY, MO | $195,417 | TAG |
| 2023 | A Novel Large Animal Model for Studying the Developmental Potential and Function of LGR5 Stem Cells in Vivo and in Vitro1R21OD034080-01 · under PAR-21-167 | PIEDRAHITA, JORGE A | NORTH CAROLINA STATE UNIVERSITY RALEIGH, NC | $190,000 | RIBT |
| 2023 | Creation of Knockout Laboratory Opossums1R21OD034473-01 · under PAR-21-167 | VANDEBERG, JOHN L | UNIVERSITY OF TEXAS RIO GRANDE VALLEY, TX | $185,000 | DBD |
| 2022 | Systematic functional study of 21st chromosome ortholog overexpression in C. elegans1R21OD032463-01 · under PAR-21-167 | PIERCE, JONATHAN THOMAS | UNIVERSITY OF TEXAS AT AUSTIN, TX | $422,421 | TAG |
| 2022 | A new mouse model to study GBA1 mutation-associated diseases with multiple organs involvement1R21OD033660-01 · under PAR-21-167 | LIU, CHUANJUSUN, YING | CINCINNATI CHILDRENS HOSP MED CTR, OH | $258,500 | TAG |
| 2022 | Direct generation of complex genetically-modified mouse models via embryonic stem cells1R21OD031973-01 · under PAR-19-369 | WEN, DUANCHENG | WEILL MEDICAL COLL OF CORNELL UNIV, NY | $254,250 | DEV1 |
| 2022 | Development and validation of genetic cell ablation systems in axolotl1R21OD031971-01A1 · under PAR-21-167 | MURAWALA, PRAYAG | MOUNT DESERT ISLAND BIOLOGICAL LAB, ME | $249,000 | DEV1 |
| 2022 | Genetic and genomic tools for C. briggsae research1R21OD030067-01A1 · under PAR-19-369 | ANDERSEN, ERIK CHRISTIANCHAMBERLIN, HELEN M | OHIO STATE UNIVERSITY, OH | $242,593 | GVE |
| 2022 | A CRISPR-based modular transgenic system to advance in vivo investigations of angiogenesis and fibrosis1R21OD032144-01 · under PAR-21-167 | WOLF, MATTHEW J | UNIVERSITY OF VIRGINIA, VA | $242,250 | MPPA |
| 2022 | Development of a mouse model of brown fat dystrophia1R21OD031907-01A1 · under PAR-21-167 | SANCHEZ-GURMACHES, JUAN | CINCINNATI CHILDRENS HOSP MED CTR, OH | $238,500 | BMDM |
| 2022 | A novel mouse model to distinguish the specific physiological significance of RNAi and biophysical mechanisms of microRNA1R21OD031965-01 · under PAR-19-369 | FU, JIDONG | OHIO STATE UNIVERSITY, OH | $236,250 | MPPA |
| 2022 | Illuminating apical extracellular matrix structure and biogenesis1R21OD033663-01 · under PAR-21-167 | CHISHOLM, ANDREW DWARD, JORDAN DAVID | UNIVERSITY OF CALIFORNIA SANTA CRUZ, CA | $234,000 | ZRG1 |
| 2022 | A Comprehensive Endogenous Basement Membrane Toolkit to Elucidate how Basement Membranes Stretch on Mechanically Active Tissues and Decline during Aging1R21OD032430-01 · under PAR-21-167 | SHERWOOD, DAVID R | DUKE UNIVERSITY, NC | $233,871 | ICI |
| 2022 | Enhancement of Human Immune System Development in Mouse Models1R21OD034048-01 · under PAR-21-167 | GORANTLA, SANTHIGURUMURTHY, CHANNABASAVAIAHPOLUEKTOVA, LARISA Y | UNIVERSITY OF NEBRASKA MEDICAL CENTER, NE | $230,250 | HIVD |
| 2022 | Development of genome-modified Xiphophorus1R21OD031910-01A1 · under PAR-21-167 | SCHARTL, MANFRED | TEXAS STATE UNIVERSITY, TX | $223,927 | DEV2 |
| 2022 | mtDNA depleter mouse for decoding mitochondrial regulation of diverse organs1R21OD031970-01 · under PAR-19-369 | SINGH, KESHAV K | UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL | $222,750 | TAG |
| 2022 | Establishment of Somatic Cell Nuclear Transfer as a Universal Platform for Cloning Marmosets1R21OD033666-01 · under PAR-21-167 | PARK, JUNG EUN | UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA | $220,800 | DEV2 |
| 2022 | Deciphering the Pathogenesis of EHEC Infection and the Effects of Bacteria-Based Therapies Using Comparative Gut-on-a-Chip1R21OD031903-01A1 · under PAR-21-167 | AMBROSINI, YOKO MIYAMOTO | WASHINGTON STATE UNIVERSITY, WA | $189,331 | CMT |
| 2022 | Developing a new chordate model for stem cell biology and regeneration1R21OD030520-01A1 · under PAR-19-369 | DE TOMASO, ANTHONY W | UNIVERSITY OF CALIFORNIA SANTA BARBARA, CA | $183,927 | DEV2 |
| 2021 | Generating mtDNA mutant mice to model human mitochondrial diseases1R21OD030076-01 · under PAR-19-369 | FAN, WEIWEI | SALK INSTITUTE FOR BIOLOGICAL STUDIES, CA | $285,000 | TAG |
| 2021 | Building transgenic tools in Acomys cahirinus, an emerging model for mammalian regenerative biology and healthy aging1R21OD030107-01 · under PAR-19-369 | MILLEN, KATHLEEN JOYCE | SEATTLE CHILDREN'S HOSPITAL, WA | $282,750 | DEV2 |
| 2021 | Collagen XVII unmasking in Parkinson's disease and scratching1R21OD030057-01A1 · under PAR-19-369 | AMBER, KYLE T. | RUSH UNIVERSITY MEDICAL CENTER, IL | $249,750 | ACTS |
| 2021 | Establish a novel mouse model tracking multiple extracellular vesicles1R21OD031906-01 · under PAR-19-369 | NAKAMURA, TAKAHISA | CINCINNATI CHILDRENS HOSP MED CTR, OH | $238,500 | BMDM |
| 2021 | Frequent concatemeric insertions during AAV6/Cas9-mediated genome editing: Detection and Prevention1R21OD030529-01 · under PAR-19-369 | MAJETI, RAVINDRANAKAUCHI, HIROMITSU | STANFORD UNIVERSITY, CA | $236,936 | TAG |
| 2021 | Generate Zebrafish Conditional Knockout Model for Ciliopathy Research1R21OD030065-01A1 · under PAR-19-369 | PARANT, JOHN M | UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL | $222,750 | TAG |
| 2021 | Advanced Image Analysis Tools for Super-Resolved MRI in Small Animals1R21OD030163-01A1 · under PAR-19-369 | PHAM, DZUNG L | HENRY M. JACKSON FDN FOR THE ADV MIL/MED, MD | $218,013 | ITD |
| 2021 | Understanding SHRF, an RNA exosome-linked disease with multi-organ involvement1R21OD030077-01 · under PAR-19-369 | LU, BINGWEI | STANFORD UNIVERSITY, CA | $197,032 | MGB |
| 2021 | Pathogenesis of HIV and HBV Co-Infection in a Humanized Mouse Model1R21OD030204-01A1 · under PAR-19-369 | AMBROSE, ZANDREAGUO, HAITAO | UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA | $195,625 | HCAC |
| 2021 | Host genetic variation affecting the microbiome in rhesus macaques1R21OD030072-01A1 · under PAR-19-369 | VALLENDER, ERIC J. | UNIVERSITY OF MISSISSIPPI MED CTR, MS | $193,750 | GVE |
| 2020 | The Burmese Python as a Model System for the Study of Metabolism and Organ Regeneration1R21OD029996-01 · under PAR-19-369 | SAEIDI, NIMASTYLOPOULOS, NICHOLAS | BOSTON CHILDREN'S HOSPITAL, MA | $279,368 | IPOD |
| 2020 | Mouse models for decoding microRNA regulation in diverse tissues and cell types1R21OD029999-01 · under PAR-19-369 | MACRAE, IAN JOHN | SCRIPPS RESEARCH INSTITUTE, THE, CA | $266,250 | MGB |
| 2020 | Anastasis biosensor for tracking reversal of apoptosis in vivo1R21OD028764-01 · under PA-16-141 | TANG, HO LAM | JOHNS HOPKINS UNIVERSITY, MD | $237,338 | CMT |
| 2020 | Bellymount: A platform for ultra-long term imaging of abdominal organs in live adult Drosophila1R21OD028273-01 · under PA-16-141 | O'BRIEN, LUCY ERIN | STANFORD UNIVERSITY, CA | $236,550 | DEV2 |
| 2020 | A comprehensive toolkit to visualize endogenously tagged fluorescent basement membrane components in a living animal1R21OD028766-01 · under PA-16-141 | SHERWOOD, DAVID R | DUKE UNIVERSITY, NC | $233,968 | ZRG1 |
| 2020 | Developing zebra finch transgenic lines with functional receptors for VSV-G-pseudotyped lentiviruses1R21OD028774-01 · under PA-16-141 | MELLO, CLAUDIO V | OREGON HEALTH & SCIENCE UNIVERSITY, OR | $231,000 | MNG |
| 2020 | Development of an exosome and cargo tracking mouse1R21OD028749-01 · under PA-16-141 | ZEMPLENI, JANOS | UNIVERSITY OF NEBRASKA LINCOLN, NE | $222,750 | ICI |
| 2020 | Optimization of homology-directed repair in zebrafish1R21OD030004-01 · under PAR-19-369 | LAWSON, NATHAN D | UNIV OF MASSACHUSETTS MED SCH WORCESTER, MA | $209,375 | DEV2 |
| 2020 | Selectable non-mosaic embryo editing1R21OD030009-01 · under PAR-19-369 | NAKAUCHI, HIROMITSU | STANFORD UNIVERSITY, CA | $202,122 | TAG |
| 2020 | Derivation of chimera competent pig embryonic stem cells under a novel condition1R21OD028763-01 · under PA-16-141 | WU, JUN | UT SOUTHWESTERN MEDICAL CENTER, TX | $163,416 | DEV2 |
| 2019 | Development and Validation of a Novel Cas13a and Nanoparticle Guide-RNA Delivery System that Allows Precise Ablation of Host Macrophage Populations in a Humanized Mouse Model1R21OD027052-01 · under PA-16-141 | WILES, MICHAEL VAN | JACKSON LABORATORY, ME | $269,900 | TAG |
| 2019 | Germ cell preservation of immunodeficient pigs utilizing embryo complementation approach1R21OD027062-01 · under PA-16-141 | LEE, KIHO | VIRGINIA POLYTECHNIC INST AND ST UNIV, VA | $241,500 | CMIR |
| 2019 | In situ imaging of collagen degradation activity in multiple myeloma and lung fibrosis mouse model1R21OD026618-01A1 · under PA-16-141 | YOON, DONGHOONYU, MICHAEL S | UNIVERSITY OF UTAH, UT | $240,000 | IPCA |
| 2019 | Tandem Genetically Encoded Voltage and Calcium Indicator Mice for Optical Physiology of Excitable Cells1R21OD025345-01A1 · under PA-16-141 | THOMPSON, CHRISTOPHER H | NORTHWESTERN UNIVERSITY AT CHICAGO, IL | $237,000 | NTRC |
| 2019 | A Single cell expression atlas of muscle and dermis during regeneration after wounding in Acomys cahirinus - an adult mammal model for de novo muscle regeneration1R21OD028209-01 · under PA-16-141 | BARBAZUK, WILLIAM B | UNIVERSITY OF FLORIDA, FL | $224,424 | ACTS |
| 2019 | Development of an in vitro mouse genetic reference platform to improve preclinical drug safety assessment1R21OD028216-01 · under PA-16-141 | MOSEDALE, MERRIE | UNIV OF NORTH CAROLINA CHAPEL HILL, NC | $223,571 | XNDA |
| 2019 | Hepatocyte-targeted somatic-cell genetic complementation in mice1R21OD026444-01A1 · under PA-16-141 | SCHMIDT, EDWARD E | MONTANA STATE UNIVERSITY - BOZEMAN, MT | $216,000 | HBPP |
| 2019 | Enhancing CRISPR-Cas for disease modeling in Xenopus1R21OD023810-01A1 · under PA-16-141 | HORB, MARKO E | MARINE BIOLOGICAL LABORATORY, MA | $207,500 | DEV1 |
| 2019 | Rapid production and dissemination of intersectional genetic alleles for the study of nervous system circuit development and function in the mouse.1R21OD025327-01A1 · under PA-16-141 | RAY, RUSSELL S | BAYLOR COLLEGE OF MEDICINE, TX | $198,125 | MNG |
| 2019 | Rapid Fluorescent Tagging of Endogenous Proteins in Mouse Models1R21OD027053-01 · under PA-16-141 | HE, LIN | UNIVERSITY OF CALIFORNIA BERKELEY, CA | $196,250 | TAG |
| 2019 | Genetic Modification to Harness the Regenerative Power of the African Spiny Mouse1R21OD028211-01 · under PA-16-141 | TERADA, NAOHIRO | UNIVERSITY OF FLORIDA, FL | $190,625 | ACTS |
| 2019 | Image-guided robot for high-throughput microinjection of Drosophila embryos1R21OD028214-01 · under PA-16-141 | GOHL, DARYLKODANDARAMAIAH, SUHASA B | UNIVERSITY OF MINNESOTA, MN | $184,118 | ISD |
| 2018 | Rapid In Vivo Modeling of Developmental Disorders1R21OD024941-01 · under PA-16-141 | MURRAY, STEPHEN A | JACKSON LABORATORY, ME | $262,500 | GHD |
| 2018 | Improved Mouse Modeling of 25 to 300-Kilobase-Scale Human Genomic Structural Variation by CRISPR/Cas9-Stimulated Homologous Recombination of BacterialArtificial Chromosome Vectors (CRISPR/BAC/HR)1R21OD023803-01A1 · under PA-16-141 | BERGSTROM, DAVID ERIC | JACKSON LABORATORY, ME | $254,375 | GHD |
| 2018 | Sry transgenic rats for investigation of XX vs. XY differences in phenotypes1R21OD026560-01 · under PA-16-141 | ARNOLD, ARTHUR PDWINELL, MELINDA RGEURTS, ARON M | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $246,045 | CMIR |
| 2018 | Generation and characterization of a novel cell subpopulation ablation model1R21OD024931-01A1 · under PA-16-141 | QIN, XUEBIN | TEMPLE UNIV OF THE COMMONWEALTH, PA | $237,750 | HAI |
| 2018 | Engraftment of human hematopoietic stem cells to immunodeficient rabbits1R21OD024789-01A1 · under PA-16-141 | BILITY, MOSES TURKLEXU, JIE | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $207,999 | TTT |
| 2018 | Establish a zebrafish genetic mosaic system for disease modeling and developmental biology1R21OD026524-01 · under PA-16-141 | ZONG, HUI | UNIVERSITY OF VIRGINIA, VA | $201,875 | NCF |
| 2018 | A New Method for Mosaic Analysis of Clonal Mutations in Mice1R21OD023822-01A1 · under PA-16-141 | ZHUANG, YUAN | DUKE UNIVERSITY, NC | $199,479 | CMIA |
| 2018 | Animal Models for SCN2A Neurodevelopmental Disorders1R21OD025330-01 · under PA-16-141 | KEARNEY, JENNIFER A | NORTHWESTERN UNIVERSITY AT CHICAGO, IL | $197,500 | NDPR |
| 2018 | Characterization of split-GAL4 driver expression in the Drosophila intestine at the Bloomington Drosophila Stock Center1R21OD026525-01 · under PA-16-141 | COOK, KEVIN RSOKOL, NICHOLAS | TRUSTEES OF INDIANA UNIVERSITY, IN | $196,875 | DEV2 |
| 2018 | Using cortico-striatal evolutionary innovations for modeling Huntington's disease1R21OD025320-01 · under PA-16-141 | MEHLER, MARK F | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC, NY | $105,902 | MNG |
| 2018 | Generation of novel Fn1-fluorescent fusion proteins in vivo for the investigation of cell-ECM dynamics in real time1R21OD025323-01 · under PA-16-141 | ASTROF, SOPHIE | THOMAS JEFFERSON UNIVERSITY, PA | $45,845 | ICI |
| 2017 | New transgenic tools for mammalian fibrosis and regenerative repair research1R21OD023838-01 · under PA-16-141 | MILLEN, KATHLEEN JOYCENELSON, BRANDEN R | SEATTLE CHILDREN'S HOSPITAL, WA | $274,883 | ACTS |
| 2017 | Identifying the genetic changes which induce tissue and organ regeneration in a novel mammalian model system.1R21OD023210-01 · under PA-13-145 | MADEN, MALCOLM | UNIVERSITY OF FLORIDA, FL | $253,531 | GCAT |
| 2017 | Optimization of Targeted Nuclease Mediated HDR Events in Inbred Mouse Zygotes1R21OD023800-01 · under PA-16-141 | WILES, MICHAEL VAN | JACKSON LABORATORY, ME | $249,375 | TAG |
| 2017 | Proximity- and complementation-based analysis of signaling complexes1R21OD023204-01 · under PA-13-145 | SOKOL, SERGEI | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY | $201,281 | ICI |
| 2017 | Resource for marking clones on the fly 4th chromosome1R21OD024794-01 · under PA-16-141 | NEWFELD, STUART J | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ | $196,805 | DEV2 |
| 2017 | A light-inducible protein trapping system for studying cellular dynamics in Drosophila1R21OD023824-01A1 · under PA-16-141 | HAN, CHUN | CORNELL UNIVERSITY, NY | $187,338 | MNG |
| 2017 | Development of conditional and inducible gene targeting tools in rabbits1R21OD023194-01A1 · under PA-16-141 | XU, JIE | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $184,063 | TAG |
| 2017 | Development of Mas Receptor Knockout Rat Resource1R21OD024781-01 · under PA-16-141 | LOMBARD, JULIAN H | MEDICAL COLLEGE OF WISCONSIN, WI | $182,875 | HM |
| 2016 | Developing techniques to generate the first transgenic opossums1R21OD022988-01 · under PA-13-145 | SEARS, KAREN E | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL | $237,900 | DEV1 |
| 2016 | RESOLVING COMPLEX SYSTEMIC ENDOGENOUS EXPRESSION PATTERNS INTO SUBCELLULAR HIGH-RESOLUTION LOCALIZATION1R21OD022981-01 · under PA-13-145 | VENKEN, KOEN JOZEF THEO | BAYLOR COLLEGE OF MEDICINE, TX | $237,750 | MGA |
| 2016 | Development of mouse models for autoinflammatory rare diseases1R21OD019928-01A1 · under PA-13-145 | KIM, DO-HYUNG | UNIVERSITY OF MINNESOTA, MN | $228,000 | HAI |
| 2016 | Investigating the Effects of Reducing Nonsense-Mediated mRNA Decay Efficiency1R21OD019922-01A1 · under PA-13-145 | KEELING, KIM MARIE | UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL | $220,500 | MGA |
| 2016 | Novel Mouse Resources for Diabetic Nephropathy1R21OD021437-01 · under PA-13-145 | KOBAYASHI, AKIO | UNIVERSITY OF WASHINGTON, WA | $217,500 | KMBD |
| 2016 | T cell-tissue interaction models1R21OD020185-01A1 · under PA-13-145 | BROWN, BRIAN D | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY | $211,875 | CMIB |
| 2016 | A novel rabbit model of cystic fibrosis1R21OD020187-01A1 · under PA-13-145 | XU, JIE | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $193,750 | LCMI |
| 2015 | Identification of autophagy mediators through screening transgenic animal library1R21OD018265-01A1 · under PA-13-145 | LEE, JUN HEE | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $266,040 | CSRS |
| 2015 | Characterization of a Temporally Controlled Dominant-Negative RB1 Mouse Model1R21OD019745-01A1 · under PA-13-145 | ROCHA-SANCHEZ, SONIA M | CREIGHTON UNIVERSITY, NE | $226,960 | AUD |
| 2015 | Targeting non-HIF-mediated regulators of hypoxic responses1R21OD019932-01 · under PA-13-145 | BAKER, KEITH D | VIRGINIA COMMONWEALTH UNIVERSITY, VA | $219,030 | CSRS |
| 2015 | Dissecting Distinct and Redundant Roles of ThPOK and LRF, Key Regulators of Hematopoiesis1R21OD017958-01A1 · under PA-13-145 | KAPPES, DIETMAR J | RESEARCH INST OF FOX CHASE CAN CTR, PA | $218,663 | ZRG1 |
| 2015 | Exome screening and directed breeding of rhesus for human genetic disease models1R21OD019930-01A1 · under PA-13-145 | JOHNSON, R. PAULNORGREN, ROBERT B. | UNIVERSITY OF NEBRASKA MEDICAL CENTER, NE | $216,028 | GHD |
| 2015 | CRISPR/Cas9 guided production of genetically engineered pigs lacking CD8+ T-cells1R21OD019934-01A1 · under PA-13-145 | LEE, KIHOYUAN, LIJUAN | VIRGINIA POLYTECHNIC INST AND ST UNIV, VA | $197,225 | CMIA |
| 2015 | Development of mouse strains with human-like telomerase regulation1R21OD021432-01 · under PA-13-145 | ZHU, JIYUE | WASHINGTON STATE UNIVERSITY, WA | $184,975 | CMAD |
| 2015 | Novel Transgenic Mouse Models for L1 Retrotransposons in Development and Disease1R21OD017965-01A1 · under PA-13-145 | AN, WENFENG | SOUTH DAKOTA STATE UNIVERSITY, SD | $178,850 | CMIR |
| 2014 | CHD5 dosage in epigenetic control of Cancer, Infertility, and Autism1R21OD018332-01 · under PA-13-145 | MILLS, ALEA A. | COLD SPRING HARBOR LABORATORY, NY | $283,500 | GHD |
| 2014 | Non-Human Primate Model for Systems Biology Studies of Stress Response1R21OD017959-01 · under PA-10-138 | JASINSKA, ANNA JOANNA | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $269,500 | BRLE |
| 2014 | Light-inducible Cre Transgenic Mouse Models1R21OD019764-01 · under PA-13-145 | BEHRINGER, RICHARD R | UNIVERSITY OF TX MD ANDERSON CAN CTR, TX | $240,000 | DEV2 |
| 2014 | Experimental Strategies for Light-Induced Elimination of Protein Function in vivo1R21OD017964-01 · under PA-10-138 | STEIN, DAVID S. | UNIVERSITY OF TEXAS AT AUSTIN, TX | $231,750 | DEV2 |
| 2014 | Development of humanized TLR4 SNP mouse models1R21OD017233-01A1 · under PA-13-145 | HAJJAR, ADELINE M | UNIVERSITY OF WASHINGTON, WA | $231,750 | IHD |
| 2014 | Developing models for identification of therapeutic cell populations1R21OD017244-01A1 · under PA-13-145 | ZIOUZENKOVA, OULIANA ZIOUZENKOVA | OHIO STATE UNIVERSITY, OH | $230,250 | ZRG1 |
| 2014 | Model for evaluation of FCGR variants in disease and response to therapeutics1R21OD012234-01A1 · under PA-10-138 | KOLLER, BEVERLY H | UNIV OF NORTH CAROLINA CHAPEL HILL, NC | $228,000 | CII |
| 2014 | Assembly of disease-relevant pathways in the mouse1R21OD016565-01A1 · under PA-10-138 | KOLLER, BEVERLY H | UNIV OF NORTH CAROLINA CHAPEL HILL, NC | $228,000 | MNG |
| 2014 | Seq-ing the etiology of birth defects in a new frog model, Lepidobatrachus laevis1R21OD017963-01A1 · under PA-13-145 | NASCONE-YODER, NANETTE M | NORTH CAROLINA STATE UNIVERSITY RALEIGH, NC | $227,250 | DEV2 |
| 2014 | Generation of a Transgenic Mouse Model to Study Human TLR9 Role in Disease1R21OD018317-01 · under PA-13-145 | GUIDUCCI, CRISTIANA | DYNAVAX TECHNOLOGIES CORPORATION, CA | $227,161 | III |
| 2014 | Gene targeting in zebrafish: building models to assay disease genes1R21OD018323-01 · under PA-13-145 | GRUNWALD, DAVID J. | UNIVERSITY OF UTAH, UT | $223,500 | DEV2 |
| 2014 | Humanized mice to study mast cell function1R21OD017843-01A1 · under PA-10-138 | ALI, HYDAR | UNIVERSITY OF PENNSYLVANIA, PA | $200,000 | LCMI |
| 2014 | Development of RhoA Optical Sensor Mice for Novel Vascular Smooth Muscle Studies1R21OD018315-01 · under PA-13-145 | RIZZO, MEGAN AWIER, WITHROW GIL | UNIVERSITY OF MARYLAND BALTIMORE, MD | $191,875 | MEDI |
| 2014 | Oxidant Stress in the Nrf2 Knockout Rat1R21OD018309-01 · under PA-13-145 | LOMBARD, JULIAN H | MEDICAL COLLEGE OF WISCONSIN, WI | $191,250 | HM |
| 2014 | Differentiation of mitochondrial vs. nuclear function of telomerase1R21OD018306-01 · under PA-13-145 | BEYER, ANDREAS M | MEDICAL COLLEGE OF WISCONSIN, WI | $191,250 | VCMB |
| 2014 | Mechanisms of PGRMC2 action in female reproduction1R21OD016564-01A1 · under PA-13-145 | PRU, JAMES K | WASHINGTON STATE UNIVERSITY, WA | $166,349 | ICER |
Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.