| #1 | Johns Hopkins University | Baltimore | School Of Medicine | $470.7M | 763 | 822 |
| #2 | University of Maryland Baltimore | Baltimore | School Of Medicine | $113.3M | 209 | 234 |
| #3 | University of Maryland, College Park | College Park | University | $42.3M | 92 | 106 |
| #4 | Westat, Inc. | Bethesda | Other | $30.6M | 6 | 17 |
| #5 | Kennedy Krieger Institute | Baltimore | Research Institute | $12.5M | 22 | 28 |
| #6 | Lieber Institute, Inc. | Baltimore | Research Institute | $10M | 11 | 13 |
| #7 | Henry M. Jackson Fdn for the Adv Mil/Med | Bethesda | Other | $8.1M | 20 | 24 |
| #8 | University of Maryland Baltimore County | Baltimore | University | $5.7M | 13 | 12 |
| #9 | Pacific Institute for Res and Evaluation | Beltsville | Research Institute | $4.2M | 5 | 8 |
| #10 | Foundation for the Nih | North Bethesda | Research Institute | $3M | 1 | 1 |
| #11 | Akyso Therapeutics, Llc | Salisbury | Other | $2.7M | 1 | 2 |
| #12 | Friends Research Institute, Inc. | Baltimore | Research Institute | $2.1M | 3 | 5 |
| #13 | Medstar Health Research Institute | Hyattsville | Research Institute | $1.9M | 4 | 6 |
| #14 | Biomedical Research Institute | Rockville | Research Institute | $1.8M | 1 | 1 |
| #15 | Scanogen, Inc. | Baltimore | Other | $1.8M | 2 | 1 |
| #16 | Fisher Bioservices, Inc. | Rockville | Other | $1.8M | 5 | 5 |
| #17 | Abvacc, Inc. | Rockville | Other | $1.7M | 2 | 2 |
| #18 | Information Management Services, Inc. | Calverton | Other | $1.6M | 1 | 0 |
| #19 | Autonomous Therapeutics, Inc. | Silver Spring | Other | $1.5M | 1 | 1 |
| #20 | Potomac Affinity Proteins, Llc | North Potomac | Other | $1.5M | 2 | 1 |
| #21 | Amplo Biotechnology, Inc. | Towson | Other | $1.4M | 1 | 2 |
| #22 | Insilica, Llc | Bethesda | Other | $1M | 1 | 1 |
| #23 | Pearl Diagnostics, Inc. | Baltimore | Other | $977.1K | 1 | 2 |
| #24 | Spirit Fit & Health Inc | Kensington | Other | $918.1K | 1 | 1 |
| #25 | Lasarrus Clinic and Research Center, Inc. | Baltimore | Other | $887.6K | 1 | 1 |
| #26 | American Gastroenterological Assn/Inst | Bethesda | Other | $813.9K | 2 | 5 |
| #27 | Accelevir Diagnostics, Llc | Baltimore | Other | $764.9K | 1 | 2 |
| #28 | Center for Construction Res and Training | Silver Spring | Other | $647.8K | 1 | 1 |
| #29 | The Emmes Company, Llc | Rockville | Other | $634K | 1 | 1 |
| #30 | Towson University | Towson | University | $528.8K | 1 | 1 |
| #31 | Morgan State University | Baltimore | University | $523.9K | 2 | 2 |
| #32 | Association /Public Health Laboratories | Bethesda | Other | $500K | 1 | 1 |
| #33 | American Assn On Health and Disability | Rockville | Other | $500K | 1 | 1 |
| #34 | Iq Solutions, Inc. | Rockville | Other | $462K | 1 | 1 |
| #35 | University of Maryland Eastern Shore | Princess Anne | University | $364K | 1 | 1 |
| #36 | Biological Mimetics, Inc. | Frederick | Other | $278K | 1 | 1 |
| #37 | Biotarget Dx Llc | Hanover | Other | $239.2K | 1 | 1 |
| #38 | Federation of Amer Soc for Exper Biology | Rockville | Other | $218.4K | 9 | 9 |
| #39 | Whitman-Walker Institute, Inc. | Washington | Research Institute | $167.5K | 1 | 1 |
| #40 | United States Association for the Study of Pain, Inc. | Annapolis | Other | $60K | 1 | 2 |
| #41 | American Speech-Language-Hearing Assn | Rockville | Other | $60K | 2 | 1 |
| #42 | Hearing Loss Association of America | Rockville | Other | $59.6K | 1 | 1 |
| #43 | Emocha Mobile Health, Inc. | Owings Mills | Other | $50K | 1 | 1 |
| #44 | North American Vascular Biology Org | Germantown | Other | $40K | 1 | 1 |
| #45 | Maryland State Department of Agriculture | Annapolis | Other | $30.8K | 1 | 1 |
| #46 | American Society/Investigative Pathology | Rockville | Other | $10K | 1 | 1 |
